CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4592765 Ki 0.22 nM
CCCCC(CC(=O)O)n1c(=O)c2ncccc2n(Cc2cn(C)c3cc(C)cc(C)c23)c1=O CHEMBL3640120 IC50 0.3 nM
CC[C@H](CC(=O)O)n1c(=O)c2ncccc2n(Cc2cn(C)c3cc(C)cc(C)c23)c1=O CHEMBL3640116 IC50 0.4 nM
C[C@@H](NC(=O)N1C(=O)[C@@H](Cc2ccccc2)[C@H]1Oc1ccc(N2CCN(C)CC2)cc1)c1ccccc1 CHEMBL1631751 IC50 0.46 nM
Cc1cc(C)c2c(Cn3c(=O)n(C(CC(=O)O)C4CC4)c(=O)c4ncccc43)cn(C)c2c1 CHEMBL3640115 IC50 0.7 nM
CC[C@H](CC(=O)O)n1c(=O)c2cnccc2n(Cc2cn(C)c3cc(C)cc(C)c23)c1=O CHEMBL3640118 IC50 0.7 nM
O=C1N(Cc2ccc3c(c2)OCO3)C(=O)N1Cc1ccc2c(c1)OCO2 CHEMBL44950 IC50 0.85 nM
CCCC[C@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640105 IC50 0.9 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(OC)c4)ncc(N)c3=O)nc2c1 CHEMBL26285 Ki 1.12 nM
CC(C)[C@H](NC(=O)CCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL353816 Ki 1.3 nM
CCCC(CC(=O)O)n1c(=O)c2ncccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640121 IC50 1.3 nM
CC[C@H](CC(=O)O)n1c(=O)c2ncccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640110 IC50 1.4 nM
CCCCC(CC(=O)O)n1c(=O)c2ncccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640119 IC50 1.4 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 CHEMBL4450993 Ki 1.7 nM
N=C(N)NCCC[C@@H]1NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N2 CHEMBL4560112 Ki 1.8 nM
COc1ccc(CN2C(=O)N(Cc3ccc(OC)cc3)C2=O)cc1 CHEMBL48083 IC50 2.0 nM
CCC[C@@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640102 IC50 2.1 nM
CC[C@H](CC(=O)O)n1c(=O)c2ncccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640111 IC50 2.2 nM
Cc1ccc(C[C@@H]2NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]3CSSC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]4CCCN4C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC2=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N3)cc1 CHEMBL4465306 Ki 2.2 nM
COc1cccc(CN2C(=O)N(Cc3cccc(OC)c3)C2=O)c1 CHEMBL45780 IC50 2.3 nM
CN(C(=O)c1cc2ccccc2cc1C(=O)C(c1cccc2ccccc12)P(=O)(O)O)C1CCN(C(=O)c2ccc3ccccc3c2)CC1 CHEMBL374027 Ki 2.3 nM
O=C(c1ccc2ccccc2c1)C(c1cccc2ccccc12)P(=O)(O)O CHEMBL424224 Ki 2.3 nM
CC[C@H](CC(=O)O)n1c(=O)c2cnccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3639389 IC50 2.5 nM
CCCC[C@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640100 IC50 2.6 nM
CC[C@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640114 IC50 2.6 nM
Nc1cnc(-c2cccc(Cl)c2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1=O CHEMBL24734 Ki 2.62 nM
CC[C@@H](C(=O)O)n1c(=O)c2ncccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640117 IC50 2.7 nM
CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)OC CHEMBL355430 Ki 3.0 nM
CC[C@@H](CC(=O)O)n1c(=O)c2ncccc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640107 IC50 3.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2cc(F)cc(F)c2)CN(C(=O)N[C@H](C)c2ccc(CC(=O)O)cc2)C1=O CHEMBL3657195 IC50 3.0 nM
CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL170200 Ki 3.1 nM
CCOc1ccccc1C[C@@H]1C(=O)N(C(=O)NC(c2ccccc2)c2ccccc2)[C@@H]1Oc1ccc(C(=O)O)cc1 CHEMBL1631756 IC50 3.1 nM
Cc1cccc2c1c(Cn1c(=O)n([C@H](C(=O)O)c3ccccc3)c(=O)c3cnccc31)cn2C CHEMBL3640095 IC50 3.1 nM
CP(=O)(O)C(C(=O)N/C=C/c1cccc(Cl)c1)c1csc2ccc(Cl)cc12 CHEMBL373916 IC50 3.5 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCC(=O)N2CCCCCC2)c1 CHEMBL26448 Ki 3.56 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL281124 Ki 3.68 nM
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL436061 Ki 3.9 nM
O=C1N(Cc2ccccc2)C(=O)N1Cc1ccccc1 CHEMBL47394 IC50 4.0 nM
CCC[C@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640103 IC50 4.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2cc(F)cc(F)c2)CN(C(=O)N[C@H](C)c2ccc(C(=O)O)c(N)c2)C1=O CHEMBL3653523 IC50 4.0 nM
COC(=O)c1ccc2oc(C(=O)[C@H](Cc3ccccc3)NC(=O)Cn3c(-c4cccc(OC)c4)ncc(N)c3=O)nc2c1 CHEMBL402185 Ki 4.8 nM
CCC[C@@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640104 IC50 4.8 nM
CCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCC)NC(=O)c1ccccc1 CHEMBL335675 IC50 5.0 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccccc4)ncc(N)c3=O)nc2c1 CHEMBL26297 Ki 5.57 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(N)c4)ncc(N)c3=O)nc2c1 CHEMBL26127 Ki 5.6 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL287318 Ki 5.6 nM
CCCC(=O)NC(CCc1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCc1ccccc1)NC(=O)CCC CHEMBL436591 IC50 5.6 nM
CC(C)C(NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL169707 Ki 5.6 nM
COC(=O)c1ccc2oc(C(=O)[C@H](Cc3ccccc3)NC(=O)Cn3c(-c4ccccc4)ncc(N)c3=O)nc2c1 CHEMBL256270 Ki 5.6 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4586444 Ki 5.7 nM
COc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OCc3cccc(C)c3)=C(CSc3nncn3CC(=O)O)CO[C@@H]21 CHEMBL76522 IC50 6.0 nM
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cc(C(=O)O)cs1 CHEMBL355132 Ki 6.0 nM
COc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OCc3cccc(C)c3)=C(CSc3nnnn3CC(=O)O)CO[C@@H]21 CHEMBL82346 IC50 6.0 nM
Cc1cccc2c1c(Cn1c(=O)n(CC(=O)O)c(=O)c3ncccc31)cn2C CHEMBL3640094 IC50 6.1 nM
CC[C@H](CC(=O)O)n1c(=O)c2ccncc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640106 IC50 6.1 nM
CC(C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL170878 Ki 6.3 nM
COC(=O)CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C CHEMBL170718 Ki 6.5 nM
N=C(N)NCCC[C@@H]1NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N2 CHEMBL4457132 Ki 6.6 nM
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(CC(=O)O)c1 CHEMBL170697 Ki 6.7 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1ccc(C(=O)O)cc1 CHEMBL170879 Ki 6.8 nM
CC[C@@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640099 IC50 7.0 nM
CCCC[C@@H](C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640101 IC50 7.0 nM
CCC[C@@H](NC(=O)N1CC2=NOCC(=O)N2CC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3657206 IC50 7.0 nM
Cc1cccc2c1c(Cc1nn(C(C(=O)O)c3ccccc3)c(=O)c3ccccc13)cn2C CHEMBL3691804 IC50 7.0 nM
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1)C(C)C CHEMBL170838 Ki 7.1 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCc1ccccc1 CHEMBL170074 Ki 7.4 nM
CC[C@@H](CC(=O)O)n1c(=O)c2ccncc2n(Cc2cn(C)c3cccc(C)c23)c1=O CHEMBL3640113 IC50 7.4 nM
C[C@@H](O)[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CCCN3C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4590739 Ki 7.5 nM
CCNC(=O)CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O CHEMBL25199 Ki 7.71 nM
CC[C@@H](CC(=O)O)n1c(=O)c2ncccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640097 IC50 8.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL4206099 IC50 8.9 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3657204 IC50 9.0 nM
CCCC(C(=O)O)n1nc(Cc2cn(C)c3cccc(C)c23)c2ccccc2c1=O CHEMBL3691803 IC50 9.0 nM
CCN(CC)C(=O)CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O CHEMBL25884 Ki 9.32 nM
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)N[C@@H](Cc1ccccc1)C(=O)O)C1CCNC(=N)N1)C(=O)N[C@H](C=O)Cc1ccccc1 CHEMBL247767 IC50 9.36 nM
Cc1cccc2c1c(Cn1c(=O)n(CC(=O)O)c(=O)c3cnccc31)cn2C CHEMBL3640093 IC50 9.6 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)Nc2cccc(C(=O)O)c2)c1 CHEMBL284702 Ki 9.7 nM
CC[C@H](CC(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640109 IC50 9.9 nM
Cn1cc(C(C(=O)Nc2ccc3ccccc3c2)P(C)(=O)O)c2cc(Cl)ccc21 CHEMBL374087 IC50 10.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2ccc(F)cc2)CN(C(=O)N[C@H](C)c2ccc(C(=O)O)c(N)c2)C1=O CHEMBL3653522 IC50 10.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2ccccn2)CN(C(=O)N[C@H](C)c2ccc(C(=O)O)c(N)c2)C1=O CHEMBL3653524 IC50 10.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2ccc(F)cc2)CN(C(=O)N[C@H](C)c2ccc(CC(=O)O)cc2)C1=O CHEMBL3657194 IC50 10.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 CHEMBL4442550 Ki 10.0 nM
COC(=O)CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O CHEMBL26182 Ki 10.2 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCC(=O)N2CCCCC2)c1 CHEMBL24707 Ki 10.2 nM
O=C(N/C=C/c1ccc(F)c(F)c1)C(c1csc2ccc(Cl)cc12)P(=O)(O)O CHEMBL373898 IC50 11.0 nM
CP(=O)(O)C(C(=O)N/C=C/c1cc(F)cc(Cl)c1)c1csc2ccc(Cl)cc12 CHEMBL374504 Ki 11.0 nM
CCCCC(Cn1c(=O)c2cnccc2n(Cc2cn(C)c3cccc(C)c23)c1=O)C(=O)O CHEMBL3640096 IC50 11.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4561218 Ki 11.0 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCC(N)=O)c1 CHEMBL25169 Ki 12.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCC(=O)OCc1ccccc1 CHEMBL172873 Ki 12.5 nM
CCCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCCC)NC(=O)c1ccccc1 CHEMBL424453 IC50 13.0 nM
Cn1cc(C(C(=O)Nc2ccc3ccccc3c2)P(=O)(O)O)c2cc(Cl)ccc21 CHEMBL223530 IC50 13.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCC(=O)O CHEMBL171676 Ki 13.1 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(N)=O)c1 CHEMBL26494 Ki 13.3 nM
COc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1 CHEMBL283786 Ki 13.8 nM
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cc(C(=O)O)c2ccccc2c1 CHEMBL170152 Ki 14.2 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(F)c4)ncc(N)c3=O)nc2c1 CHEMBL287133 Ki 14.3 nM
Nc1cnc(-c2cccc(F)c2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1=O CHEMBL284005 Ki 15.7 nM
Cn1cc(C(C(=O)N/C=C/c2ccc(F)cc2)P(=O)(O)O)c2cc(Cl)ccc21 CHEMBL373899 IC50 16.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1ccccc1 CHEMBL352917 Ki 16.3 nM
CC(C)[C@H](NS(C)(=O)=O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL171801 Ki 16.5 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)Nc2ccc(C(=O)O)cc2)c1 CHEMBL284138 Ki 16.6 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCC(=O)O)c1 CHEMBL442146 Ki 16.9 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1 CHEMBL25833 Ki 16.9 nM
CC[C@@H](CC(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640098 IC50 17.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(Cl)c(Cl)c1 CHEMBL304729 IC50 18.0 nM
O=c1[nH]c2cc(Cl)ccc2c(=O)n1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL245539 IC50 18.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCCc1ccccc1 CHEMBL171119 Ki 18.3 nM
CCCCCNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O CHEMBL24697 Ki 18.5 nM
COc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OCc3ccc(C(=O)O)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL80234 IC50 19.0 nM
COc1cc(Cl)c(F)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL3651441 IC50 19.0 nM
COC(=O)C[C@@H]1C(=O)NC[C@H](Cc2cc(F)ccc2OC)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL3651443 IC50 19.0 nM
N=C(N)NCCC[C@@H]1NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N2 CHEMBL4554739 Ki 19.0 nM
Cc1ccc(N2CC(=O)N(S(=O)(=O)c3ccc(Cl)c(Cl)c3)C2=O)cc1C CHEMBL442366 IC50 20.0 nM
CC(C)(C(=O)OC(=O)C(C)(C)C(CCc1ccccc1)NC(=O)c1ccccc1)C(CCc1ccccc1)NC(=O)c1ccccc1 CHEMBL134821 IC50 20.0 nM
CC[C@H](CC(=O)O)n1c(=O)c2ccncc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640108 IC50 20.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OCC)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653514 IC50 20.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OCCO)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653517 IC50 20.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2cc(F)cc(F)c2)CN(C(=O)N[C@H](C)c2ccc(C(=O)O)cc2)C1=O CHEMBL3653521 IC50 20.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2ccccn2)CN(C(=O)N[C@H](C)c2ccc(CC(=O)O)cc2)C1=O CHEMBL3657196 IC50 20.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2cc(F)cc(F)c2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(O)c1 CHEMBL3657197 IC50 20.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1nnn[nH]1 CHEMBL3657200 IC50 20.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(-c3ccccc3)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 CHEMBL4469390 Ki 20.0 nM
Cn1cc(C(C(=O)N/C=C/c2ccc(F)c(F)c2)P(C)(=O)O)c2cc(Cl)ccc21 CHEMBL376054 IC50 21.0 nM
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(N)=O)c1 CHEMBL366721 Ki 21.1 nM
COc1ccc(S(=O)(=O)N2C(=O)CN(c3ccc(C)c(C)c3)C2=O)cc1OC CHEMBL68915 IC50 22.0 nM
Cc1cccc2scc(Cn3c(SCCCC(=O)O)nc4ccccc43)c12 CHEMBL1807642 IC50 22.0 nM
CCCCNS(=O)(=O)c1cccc(NC(=O)C(F)(F)C(=O)C(Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)C(CCC(=O)O)NC(=O)OC(C)(C)C)c1 CHEMBL433799 Ki 22.8 nM
O=C1CN(c2ccc(Cl)c(Cl)c2)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL305800 IC50 23.0 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCCC(=O)O)c1 CHEMBL24071 Ki 23.0 nM
COc1cc(Cl)c(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL428927 IC50 23.0 nM
COC(=O)c1ccc2oc(C(=O)[C@H](Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL256258 Ki 23.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCCCC(=O)O CHEMBL173989 Ki 24.0 nM
CCCOc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OCc3ccc(C(=O)O)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL312329 IC50 24.0 nM
COC(=O)COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL3651445 IC50 24.0 nM
Cc1c(C)n(C)c2c(Cn3c(=O)n(CCC(=O)O)c4ccccc43)cc(Cl)cc12 CHEMBL1807640 IC50 25.0 nM
CCC(C)Oc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OCc3ccc(C(=O)O)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL80420 IC50 26.0 nM
COc1ccc(F)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL246965 IC50 26.0 nM
CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1 CHEMBL231813 IC50 26.0 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(Cl)c4)ncc(N)c3=O)nc2c1 CHEMBL25830 Ki 26.1 nM
CCOc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OCc3ccc(C(=O)O)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL295221 IC50 27.0 nM
COc1ccc(Cl)cc1C[C@H]1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL247185 IC50 27.0 nM
COc1ccc(C#N)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL247168 IC50 27.0 nM
CC[C@@H](CC(=O)O)n1c(=O)c2ccncc2n(Cc2nsc3cc(C)cc(C)c23)c1=O CHEMBL3640112 IC50 27.0 nM
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(S(N)(=O)=O)c1 CHEMBL171769 Ki 27.5 nM
CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C CHEMBL170683 Ki 28.7 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2cccnc2)c1 CHEMBL284495 Ki 28.9 nM
COC(=O)c1ccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)cc1 CHEMBL69677 IC50 29.0 nM
O=C(Nc1ccc2ccccc2c1)C(c1csc2ccc(Cl)cc12)P(=O)(O)O CHEMBL387130 IC50 29.0 nM
Cc1ccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)cc1C CHEMBL308215 IC50 30.0 nM
CCOC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL290574 Ki 30.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccn2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 CHEMBL3653513 IC50 30.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653515 IC50 30.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OC(C)C)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653516 IC50 30.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OCC(F)(F)F)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653518 IC50 30.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OC)N(C)CC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653525 IC50 30.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1cncc(C(=O)O)c1 CHEMBL3657198 IC50 30.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(CC(=O)O)cc1 CHEMBL3657201 IC50 30.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1cccc(C(=O)O)c1 CHEMBL3657203 IC50 30.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OCC)NCC(Cc2cc(F)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3657207 IC50 30.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NC(Cc1ccccc1)C(=O)O CHEMBL369796 Ki 30.1 nM
CCCCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCCCC)NC(=O)c1ccccc1 CHEMBL135080 IC50 32.0 nM
CC(C)(C)NC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C)C(C)(C)C CHEMBL218394 IC50 32.0 nM
Nc1cnc(-c2ccccc2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1=O CHEMBL284017 Ki 32.5 nM
CCN(CC)C(=O)CCNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O CHEMBL26333 Ki 33.7 nM
COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL391608 IC50 34.0 nM
COc1cc(Cl)ccc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL391543 IC50 34.0 nM
Cc1ccc(N2CC(=O)N(S(=O)(=O)c3ccc(Cl)cc3)C2=O)cc1C CHEMBL443008 IC50 35.0 nM
Cc1cccc2c1c(Cn1c(=O)n(CC(=O)O)c(=O)c3ccncc31)cn2C CHEMBL3640092 IC50 36.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCCC(=O)O CHEMBL170402 Ki 36.4 nM
CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL367094 Ki 36.6 nM
CCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CC)NC(=O)c1ccccc1 CHEMBL134068 IC50 37.0 nM
CO[C@@]1(NC(=O)c2ccccc2OC(C)C)C(=O)N2C(C(=O)OCc3ccc(C(=O)O)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL309488 IC50 37.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 CHEMBL4441622 Ki 37.0 nM
O=C(O)COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL246964 IC50 39.0 nM
N#Cc1ccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)cc1 CHEMBL68946 IC50 40.0 nM
CCCC(CC(=O)O)n1c(=O)n(Cc2cc(Br)cc3c2CC(=O)N3)c2ccccc21 CHEMBL2381483 IC50 40.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/N(C)C)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3653519 IC50 40.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2cc(F)cc(F)c2)CN(C(=O)NCc2ccc(C(=O)O)c(N)c2)C1=O CHEMBL3657199 IC50 40.0 nM
CCC[C@@H](NC(=O)N1C/C(=N/OCC)NCC(Cc2cc(Cl)ccc2F)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3657208 IC50 40.0 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc([N+](=O)[O-])c4)ncc(N)c3=O)nc2c1 CHEMBL284350 Ki 41.8 nM
CNC(=O)COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL396067 IC50 42.0 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccncc4)ncc(N)c3=O)nc2c1 CHEMBL23999 Ki 43.5 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(C)c4)ncc(N)c3=O)nc2c1 CHEMBL26286 Ki 44.2 nM
O=C1N(c2ccc3c(c2)OCO3)C(=O)N1c1ccc2c(c1)OCO2 CHEMBL45126 IC50 48.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3cccc(C(F)(F)F)c3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL78842 IC50 50.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3cccc(C)c3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL76624 IC50 50.0 nM
CP(=O)(O)C(C(=O)N/C=C/c1ccccc1)c1csc2ccc(Cl)cc12 CHEMBL222204 IC50 50.0 nM
CCCC(Cn1c(=O)n(Cc2cc(Br)cc3[nH]c(=O)sc23)c2ccccc21)C(=O)O CHEMBL2381480 IC50 50.0 nM
COc1ccc(Cl)cc1CC1CN/C(=N\Oc2ccc(F)cc2)CN(C(=O)N[C@H](C)c2ccc(C(=O)O)cc2)C1=O CHEMBL3653520 IC50 50.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)s1 CHEMBL3653526 IC50 50.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1nc(C(=O)O)cs1 CHEMBL3657202 IC50 50.0 nM
Cc1cccc2c1c(Cc1nn(CC(=O)O)c(=O)c3ccccc13)cn2C CHEMBL3691797 IC50 50.0 nM
CC[C@@H](NC(=O)N1C/C(=N/Oc2ccccc2)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 CHEMBL4210939 IC50 50.0 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)F)c1 CHEMBL280377 Ki 50.6 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N2 CHEMBL4464900 Ki 54.0 nM
N=C(N)NCCC[C@@H]1NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N2 CHEMBL4556207 Ki 54.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F CHEMBL147013 Ki 55.8 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(S(C)(=O)=O)c1 CHEMBL129901 IC50 56.0 nM
COC(=O)c1ccc2nc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)oc2c1 CHEMBL285306 Ki 56.3 nM
CO[C@@]1(NC(=O)c2ccccc2Oc2ccccc2)C(=O)N2C(C(=O)OCc3ccc(C(=O)O)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL79042 IC50 57.0 nM
CCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCC)NC(=O)c1ccccc1 CHEMBL131704 IC50 58.0 nM
CP(=O)(O)C(C(=O)N/C=C/c1ccc(F)c(F)c1)c1csc2ccc(Cl)cc12 CHEMBL222832 IC50 58.0 nM
CCN(CC)C(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL284545 Ki 59.5 nM
Cc1ccc(N2CC(=O)N(S(=O)(=O)c3ccc(C)c(C)c3)C2=O)cc1C CHEMBL69714 IC50 60.0 nM
O=C(N/C=C/c1ccccc1)C(c1csc2ccc(Cl)cc12)P(=O)(O)O CHEMBL223303 IC50 60.0 nM
CCCC(Cn1c(=O)n(Cc2cc(Br)cc3c2CC(=O)N3)c2ccccc21)C(=O)O CHEMBL2381482 IC50 60.0 nM
CC[C@@H](NC(=O)N1Cc2nnc(O)n2CC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL3657205 IC50 60.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nc3ncccc3o2)c1=O CHEMBL283146 Ki 60.6 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4449838 Ki 64.0 nM
Cc1cc(Cn2c(=O)n(CCC(=O)O)c3ccccc32)c2c(c1)c(C)c(C)n2C CHEMBL1807638 IC50 65.0 nM
CC(NC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)C(=O)O CHEMBL171805 Ki 65.6 nM
O=C1CN(c2cccc(Cl)c2)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL69969 IC50 66.0 nM
O=C(N/C=C/c1ccc(F)cc1)C(c1csc2ccc(Cl)cc12)P(=O)(O)O CHEMBL222952 IC50 66.0 nM
N#Cc1cccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)c1 CHEMBL431187 IC50 68.0 nM
CCNC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL25776 Ki 68.6 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3cccc(C)c3)=C(CSc3nnnn3CC(=O)O)CO[C@@H]21 CHEMBL78373 IC50 70.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3cccc(Br)c3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL80474 IC50 70.0 nM
Cc1cccc2scc(Cn3c(=O)n(CCC(=O)O)c4ccccc43)c12 CHEMBL1807526 IC50 70.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)N(C)Cc1ccccc1 CHEMBL171492 Ki 70.1 nM
COc1ccc2oc(C(=O)[C@H](Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL255328 Ki 73.0 nM
COc1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL24281 Ki 73.3 nM
Nc1cnc(-c2cccnc2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1=O CHEMBL23910 Ki 74.3 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nc3cc(C(=O)O)ccc3o2)c1=O CHEMBL22979 Ki 76.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3cccc(C)c3)=C(CSc3nnc(C)s3)CO[C@@H]21 CHEMBL307172 IC50 77.0 nM
COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccnc4)ncc(N)c3=O)nc2c1 CHEMBL24647 Ki 77.4 nM
CCO/N=C1/CN(C(=O)N[C@H](CC)c2ccc(C(=O)O)c(N)c2)C(=O)[C@H](Cc2cc(Cl)ccc2OC)CN1 CHEMBL4202858 IC50 78.0 nM
CP(=O)(O)C(C(=O)Nc1ccc2ccccc2c1)c1csc2ccc(Cl)cc12 CHEMBL373846 IC50 80.0 nM
O=C1S/C(=C\c2ccsc2)C(=O)N1C(=O)c1ccc2ccccc2c1 CHEMBL99764 Inhibitory activity 81.0 nM
COC(=O)c1cccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)c1 CHEMBL304838 IC50 82.0 nM
CC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(S(C)(=O)=O)c1 CHEMBL335613 IC50 82.0 nM
CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(F)(F)F CHEMBL2372355 Ki 82.1 nM
CCOc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL246762 IC50 83.0 nM
Nc1cnc(-c2ccncc2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1=O CHEMBL275228 Ki 84.7 nM
CCCC(C(=O)O)n1nc(Cc2cccc3ccccc23)c2ccccc2c1=O CHEMBL3691801 IC50 86.0 nM
Cn1cc(C(C(=O)Nc2ccc3ccccc3c2)P(=O)(O)O)c2ccccc21 CHEMBL373439 IC50 90.0 nM
CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O CHEMBL26496 Ki 90.7 nM
COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)c(N)c2)C1=O CHEMBL3651442 IC50 93.0 nM
CCCC(C(=O)O)n1nc(Cc2cn(C)c3ccccc23)c2ccccc2c1=O CHEMBL3691805 IC50 93.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nc3cc(F)ccc3o2)c1=O CHEMBL26171 Ki 93.1 nM
NC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL26011 Ki 94.0 nM
Cc1ccc(/C=C2\SC(=O)N(C(=O)c3ccc4ccccc4c3)C2=O)o1 CHEMBL420264 Inhibitory activity 97.0 nM
Cc1cccc2scc(Cn3c(=O)n(CCCC(=O)O)c4ccccc43)c12 CHEMBL1807643 IC50 97.0 nM
COc1ccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)cc1OC CHEMBL303431 IC50 110.0 nM
O=C1CN(S(=O)(=O)c2ccc(Cl)cc2)C(=O)C(Cc2ccccc2Cl)CN1 CHEMBL246961 IC50 110.0 nM
O=C(Nc1ccc2ccccc2c1)C(c1csc2ccccc12)P(=O)(O)O CHEMBL223582 IC50 120.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)N[C@@H](Cc2ccccc2)C(=O)c2nc3ccccc3o2)c1=O CHEMBL403531 Ki 120.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nc3ccccc3o2)c1=O CHEMBL285101 Ki 125.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1cccc(Cl)c1 CHEMBL303871 IC50 130.0 nM
CC(C)(C(=O)OC(=O)C(C)(C)C(NC(=O)c1ccc(C#N)cc1)C1CC=CCC1)C(NC(=O)c1ccc(C#N)cc1)C1CC=CCC1 CHEMBL134024 IC50 130.0 nM
Cc1ccc(N2C(=O)N(c3ccc(C)cc3)C2=O)cc1 CHEMBL296771 IC50 140.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3ccccc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL312002 IC50 140.0 nM
COc1ccccc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL246962 IC50 140.0 nM
Cc1c(C)n(C)c2c(Cn3c(=O)n(CCC(=O)O)c4ccccc43)cccc12 CHEMBL1807637 IC50 140.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL246560 IC50 140.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3cccc(C)c3)=C(CCl)CO[C@@H]21 CHEMBL77501 IC50 150.0 nM
CCCCCCC(NC(=O)c1ccc(C#N)cc1)C(C)(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)C CHEMBL111705 IC50 150.0 nM
O=C1CN(S(=O)(=O)c2ccc(Cl)cc2)C(=O)C(Cc2ccccc2F)CN1 CHEMBL395684 IC50 150.0 nM
O=C(O)Cn1nc(Cc2cccc3ccccc23)c2ccccc2c1=O CHEMBL3691798 IC50 150.0 nM
Cc1c(S(=O)(=O)Nc2ccc(C(=O)NCC(=O)O)cc2S(C)(=O)=O)sc2ccc(F)cc12 CHEMBL130156 IC50 154.0 nM
Cc1c(S(=O)(=O)Nc2ccc(C(=O)NC(CO)C(=O)O)cc2S(C)(=O)=O)sc2ccc(F)cc12 CHEMBL131605 IC50 159.0 nM
CCP(=O)(O)C(C(=O)Nc1ccc2ccccc2c1)c1csc2ccc(Cl)cc12 CHEMBL374944 IC50 160.0 nM
COc1ccc(Cl)cc1/C=C1\CNC(=O)CN(S(=O)(=O)c2cc(F)c(Cl)cc2OC)C1=O CHEMBL3651438 IC50 160.0 nM
Cc1cccc2c1c(Cc1nn(CCC(=O)O)c(=O)c3ccccc13)cn2C CHEMBL3691799 IC50 160.0 nM
CCP(=O)(O)C(C(=O)N/C=C/c1ccc(F)c(F)c1)c1csc2ccc(Cl)cc12 CHEMBL223183 IC50 165.0 nM
O=C1CN(c2ccc(Cl)c(Cl)c2)C(=O)N1S(=O)(=O)c1ccc(Cl)c(Cl)c1 CHEMBL439755 IC50 170.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(Br)cc1 CHEMBL305066 IC50 170.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3ccc(C)cc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL312461 IC50 170.0 nM
Cc1cccc2c1c(Cn1c(=O)n(CCC(=O)O)c3ccccc31)cn2C CHEMBL1807531 IC50 170.0 nM
O=C(O)C(c1ccccc1)n1nc(Cc2cccc3ccccc23)c2ccccc2c1=O CHEMBL3691800 IC50 170.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nc3cc(-c4ccccc4)ccc3o2)c1=O CHEMBL286319 Ki 174.0 nM
CCOc1ccccc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL246760 IC50 180.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)N[C@@H](Cc2ccccc2)C(=O)c2nc3ccccc3s2)c1=O CHEMBL258367 Ki 180.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nc3ccccc3s2)c1=O CHEMBL26342 Ki 182.0 nM
Nc1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)nc2c1 CHEMBL23870 Ki 183.0 nM
O=C(Nc1ccc2ccccc2c1)C(c1cccc2ccccc12)P(=O)(O)O CHEMBL376079 IC50 190.0 nM
COCc1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(S(C)(=O)=O)c1 CHEMBL132617 IC50 192.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1cccc(C(=O)O)c1 CHEMBL245532 IC50 200.0 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)c(S(C)(=O)=O)c1 CHEMBL129879 IC50 203.0 nM
CP(=O)(O)C(C(=O)Nc1ccc2ccccc2c1)c1cccc2ccccc12 CHEMBL223624 IC50 210.0 nM
O=C1CN(c2ccccc2Cl)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL69611 IC50 220.0 nM
CCCCCCC(NC(=O)c1ccc(C#N)cc1)C(C)(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCC CHEMBL108294 IC50 220.0 nM
CCCOc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL246963 IC50 220.0 nM
COc1cc(Cn2c(=O)n(CCC(=O)O)c3ccccc32)c2c(c1)c(C)c(C)n2C CHEMBL1807639 IC50 220.0 nM
O=C(Nc1ccc2ccccc2c1)C(c1csc2ccc(Cl)cc12)P(=O)(O)CCc1ccccc1 CHEMBL373820 IC50 240.0 nM
CCCC(CC(=O)O)n1c(=O)n(Cc2cc(Cl)cc3c2CC(=O)N3)c2ccccc21 CHEMBL2381484 IC50 240.0 nM
CCO/N=C1/CN(C(=O)N[C@H](CC)c2ccc(C(=O)O)cc2)C(=O)[C@H](Cc2cc(Cl)ccc2OC)CN1 CHEMBL4216202 IC50 240.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL310959 IC50 250.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1nnn[nH]1 CHEMBL2397003 IC50 260.0 nM
COc1ccc(Cl)cc1C[C@H]1CNC(=O)[C@@H](C)N(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL3651440 IC50 260.0 nM
CC(C)(C(=O)OC(=O)C(C)(C)C(CCc1ccccc1)NC(=O)c1ccc(C#N)cc1)C(CCc1ccccc1)NC(=O)c1ccc(C#N)cc1 CHEMBL108540 IC50 270.0 nM
COc1ccc(/C=C/NC(=O)C(c2csc3ccc(Cl)cc23)P(=O)(O)O)cc1 CHEMBL223014 IC50 280.0 nM
CCCCOc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O CHEMBL395822 IC50 280.0 nM
Cc1cc(C)c2c(Cn3c(=O)n(CCC(=O)O)c4ccccc43)nsc2c1 CHEMBL1807535 IC50 280.0 nM
O=C1CN(c2ccc(Cl)cc2)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL305175 IC50 300.0 nM
COc1ccc(CC(=O)N[C@]2(OC)C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(CSc4nnnn4C)CO[C@@H]32)cc1 CHEMBL263304 IC50 300.0 nM
CO[C@@]1(NC(=O)Cc2ccccc2)C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL263015 IC50 300.0 nM
Cc1ccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)cc1 CHEMBL60715 IC50 300.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL245930 IC50 300.0 nM
Cn1cc(Cc2nn(CC(=O)O)c(=O)c3ccccc23)c2ccccc21 CHEMBL3691796 IC50 300.0 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccccc3c2C)c(S(C)(=O)=O)c1 CHEMBL133635 IC50 305.0 nM
O=C(Nc1nnc(Sc2nc3ccccc3s2)s1)c1ccc(Cl)cc1 CHEMBL98042 Inhibitory activity 308.0 nM
O=C1CN(S(=O)(=O)c2ccc(Cl)cc2)C(=O)C(Cc2cccc(Cl)c2)CN1 CHEMBL395683 IC50 310.0 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(C)cc3c2C)c(S(C)(=O)=O)c1 CHEMBL131795 IC50 325.0 nM
Cc1c(S(=O)(=O)Nc2ccc(CO)cc2S(C)(=O)=O)sc2ccc(F)cc12 CHEMBL339348 IC50 337.0 nM
CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 CHEMBL394641 IC50 340.0 nM
O=C(CCc1ccccc1F)N[C@@H](Cc1ccccc1)C(=O)CCl CHEMBL62160 IC50 360.0 nM
Cn1cc(Cc2nn(C(C(=O)O)c3ccccc3)c(=O)c3ccccc23)c2ccccc21 CHEMBL3691802 IC50 360.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(F)cc1 CHEMBL71362 IC50 370.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL69991 IC50 380.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1cc(N)cc(C(=O)O)c1 CHEMBL2397001 IC50 380.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1cc(C(=O)O)co1 CHEMBL2397008 IC50 380.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1cncc(C(=O)O)c1 CHEMBL2397007 IC50 380.0 nM
Cc1cccc(CC2CNC(=O)CN(S(=O)(=O)c3ccc(Cl)cc3)C2=O)c1 CHEMBL3651439 IC50 390.0 nM
O=C(CCc1cccc(Cl)c1Cl)N[C@@H](Cc1ccccc1)C(=O)CCl CHEMBL62222 IC50 400.0 nM
O=C(N[C@@H](Cc1ccccc1)C(=O)CCl)OCc1ccccc1 CHEMBL303579 IC50 400.0 nM
CO[C@@]1(NC(=O)Cc2ccc(N(C)C)cc2)C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL79076 IC50 410.0 nM
CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(O)c(C(=O)O)c1 CHEMBL396333 IC50 410.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1nc(C(=O)O)co1 CHEMBL2397009 IC50 410.0 nM
O=C1CN(S(=O)(=O)c2ccc(Cl)cc2)C(=O)C(Cc2ccccc2)CN1 CHEMBL245541 IC50 420.0 nM
CO[C@@]1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3ccccc3C)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL76430 IC50 430.0 nM
Cc1cccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)c1 CHEMBL291397 IC50 430.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)NCc2ccccc2)c1=O CHEMBL24670 Ki 440.0 nM
O=C1CN(S(=O)(=O)c2ccc(Cl)cc2)C(=O)C(Cc2ccc(Cl)cc2)CN1 CHEMBL246960 IC50 460.0 nM
CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(O)c1 CHEMBL247975 IC50 460.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1ccc(C)c(C(=O)O)c1 CHEMBL3651444 IC50 460.0 nM
CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 CHEMBL247779 IC50 470.0 nM
Cc1cccc(-c2ncc(N)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)C(F)(F)C(=O)N(C)C)c1 CHEMBL24211 Ki 489.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N2 CHEMBL4074776 Ki 490.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)N1CCCC1C(=O)O CHEMBL368262 Ki 493.0 nM
COC(=O)Cc1cccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)c1 CHEMBL304338 IC50 500.0 nM
CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)N[C@@H](Cc1ccccc1)C(=O)O CHEMBL171354 Ki 513.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)o1 CHEMBL2397011 IC50 520.0 nM
CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1cccc(C(=O)O)c1 CHEMBL248180 IC50 540.0 nM
COc1ccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)cc1 CHEMBL70068 IC50 550.0 nM
COc1ccccc1C(=O)N[C@]1(OC)C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CSc3nnnn3C)CO[C@@H]21 CHEMBL309201 IC50 550.0 nM
Cc1cc2cccc(Cn3c(=O)n(CCC(=O)O)c4ccccc43)c2n1C CHEMBL1807537 IC50 570.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1ccc(O)c(C(=O)O)c1 CHEMBL2397000 IC50 570.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL2396929 IC50 570.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 CHEMBL4216645 IC50 570.0 nM
COc1cccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)c1 CHEMBL65936 IC50 580.0 nM
CC[C@@H](NC(=O)N1C/C(=N/OC(C)C)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 CHEMBL4214910 IC50 580.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)C2=NCCO2)c1=O CHEMBL281524 Ki 589.0 nM
Nc1cnc(-c2ccc(F)cc2)n(CC(=O)N[C@@H](Cc2ccccc2)C(=O)C2=NCCO2)c1=O CHEMBL255329 Ki 590.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N2 CHEMBL4083086 Ki 590.0 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)c(S(C)(=O)=O)c1C CHEMBL130716 IC50 594.0 nM
O=C(CCc1ccccc1Cl)N[C@@H](Cc1ccccc1)C(=O)CCl CHEMBL64202 IC50 600.0 nM
O=C(O)CCn1c(=O)n(Cc2cccc3ccccc23)c2ccccc21 CHEMBL1807530 IC50 600.0 nM
COC(=O)c1ccc(C(=O)n2cnc3cc4ccccc4cc3c2=O)cc1 CHEMBL419156 Inhibitory activity 610.0 nM
Cn1ccc2cccc(Cn3c(=O)n(CCC(=O)O)c4ccccc43)c21 CHEMBL1807536 IC50 620.0 nM
CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(N)c(C(=O)O)c1 CHEMBL245360 IC50 630.0 nM
Cc1cccc2c(C#N)cc(Cn3c(=O)n(CCC(=O)O)c4ccccc43)n12 CHEMBL1807534 IC50 640.0 nM
Cc1cn(C)c2c(Cn3c(=O)n(CCC(=O)O)c4ccccc43)cccc12 CHEMBL1807538 IC50 640.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1cccc(N)c1 CHEMBL2396997 IC50 660.0 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)c(OC)c1 CHEMBL337691 IC50 663.0 nM
Cc1ccc(/C=C2\SC(=O)N(C(=O)c3cccc(-c4ccccc4)c3)C2=O)o1 CHEMBL317161 Inhibitory activity 683.0 nM
O=C1S/C(=C/c2ccc(O)cc2)C(=O)N1S(=O)(=O)c1ccc2ccccc2c1 CHEMBL319157 Inhibitory activity 691.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 CHEMBL273334 IC50 700.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc([N+](=O)[O-])cc1 CHEMBL69009 IC50 700.0 nM
O=C(CCc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)CCl CHEMBL64495 IC50 710.0 nM
COc1cccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)c1 CHEMBL59988 IC50 730.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1ccc(N)c(C(=O)O)c1 CHEMBL2396999 IC50 730.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4462421 Ki 740.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1ccc(C(=O)O)cc1 CHEMBL2396996 IC50 770.0 nM
Cc1ccccc1CCC(=O)N[C@@H](Cc1ccccc1)C(=O)CCl CHEMBL60495 IC50 780.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1ccc(N)cc1 CHEMBL2396998 IC50 790.0 nM
O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1cccc(Oc2ccccc2)c1 CHEMBL69564 IC50 800.0 nM
CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1c[nH]c(C(=O)O)c1 CHEMBL2397002 IC50 850.0 nM
O=C(O)c1cccc(S(=O)(=O)N2C(=O)CN(c3ccccc3)C2=O)c1 CHEMBL66504 IC50 860.0 nM
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)c([N+](=O)[O-])c1 CHEMBL335761 IC50 880.0 nM
O=C(CCc1cccc(Cl)c1)N[C@@H](Cc1ccccc1)C(=O)CCl CHEMBL59660 IC50 890.0 nM
COc1cccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)c1OC CHEMBL61059 IC50 890.0 nM
CN1CCN(C(=O)c2cccc(S(=O)(=O)N3C(=O)CN(c4ccccc4)C3=O)c2)CC1 CHEMBL68428 IC50 900.0 nM
CCCS(=O)(=O)c1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1 CHEMBL328395 IC50 909.0 nM
O=C(Nc1ccc2ccccc2c1)C(c1c[nH]c2ccccc12)P(=O)(O)O CHEMBL222314 IC50 920.0 nM
CC[C@@H](NC(=O)N1CC(=O)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cn1 CHEMBL2397006 IC50 1000.0 nM