CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 CHEMBL559612 Log Ki -0.19 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(CO)C[C@H]21 CHEMBL41721 Log Ki -0.14 nM
O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1cc(Cl)ccc1-2 CHEMBL376700 Ki 0.00035 nM
Cc1c(C(=O)N[C@@H]2CCCC[C@@H]2O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4062749 pKi 0.01 nM
O=C(NC12CC3CC(CC1C3)C2)c1nn(-c2cnccn2)c2c1CC1CCC2O1 CHEMBL4873473 EC50 0.02 nM
O=C(NC12CCC(CC1)CC2)c1nn(-c2c[n+]([O-])ccn2)c2c1CC1CCC2O1 CHEMBL4847866 EC50 0.02 nM
CC(C)C(=O)N[C@@H]1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063237 Ki 0.03 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NC1CC1 CHEMBL4169198 EC50 0.03 nM
CC(C)C(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063236 Ki 0.04 nM
O=C(NC1(C(F)(F)F)CCC1)c1nn(-c2cnccn2)c2c1CC1CCC2O1 CHEMBL4862304 EC50 0.04 nM
CCC(C)(C)c1noc(-c2nn(-c3cnccn3)c3c2CC2CCC3O2)n1 CHEMBL4875720 EC50 0.04 nM
O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)C1CCCCC1 CHEMBL2063239 Ki 0.05 nM
O=C(NC12CC(C1)C2)c1nn(-c2c[n+]([O-])ccn2)c2c1CC1CCC2O1 CHEMBL4846759 EC50 0.05 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL307696 Ki 0.06 nM
CC(C)(C)c1nnc(-c2nn(-c3c[n+]([O-])ccn3)c3c2CC2CCC3O2)s1 CHEMBL4865162 EC50 0.06 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCCC(F)(F)F)cc1 CHEMBL4095223 Ki 0.062 nM
O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)C1CCOCC1 CHEMBL2063240 Ki 0.07 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NC(C)CO CHEMBL4177060 EC50 0.07 nM
N#CC1(C(=O)NC2CCCOc3c2nn(-c2ccccc2Cl)c3-c2ccc(Cl)cc2)CC1 CHEMBL2063246 Ki 0.08 nM
O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)c1cnon1 CHEMBL2063249 Ki 0.08 nM
O=C(NC12CC3CC(CC1C3)C2)c1nn(-c2ccc(F)cc2F)c2c1CC1CCC2O1 CHEMBL4872695 EC50 0.08 nM
CC(C)(CCCCCCC#N)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL5091754 EC50 0.088 nM
CC(C)(C)[C@@H](CO)NC(=O)c1nn(-c2cnccn2)c2c1C[C@H]1CC[C@@H]2O1 CHEMBL4871491 EC50 0.09 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL220360 IC50 0.094 nM
CC(C)(CCCCCCN=[N+]=[N-])c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL5081770 EC50 0.098 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL111724 Ki 0.1 nM
CC(F)(F)Cn1cnc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c1=O CHEMBL425047 Ki 0.1 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2ncn1CC(F)(F)F CHEMBL204188 Ki 0.1 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(C3CC3)cc(C(F)(F)F)c2)CC1 CHEMBL489438 IC50 0.1 nM
Cc1c(-c2cn(C(C)(C)c3ccccc3)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL584889 Ki 0.1 nM
Cc1c(-c2cn(C(C)(C)c3ccccc3)cn2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL578969 Ki 0.1 nM
NC(=O)Cc1c(C(=O)N2CCC(O)(c3ccc(F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL604904 IC50 0.1 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCCCF)cc1 CHEMBL4078689 pKi 0.1 nM
Cc1c(C(=O)N[C@H]2CCC[C@H](O)C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4100882 pKi 0.1 nM
Cc1c(C(=O)Nc2ccc(F)nc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4094098 pKi 0.1 nM
O=C(CC1CCCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4244751 Ke 0.1 nM
CCCCCn1/c(=N\C(=O)C23CC4CC(CC(C4)C2)C3)sc2ccccc21 CHEMBL4437741 Ki 0.1 nM
N#CC1(c2ccccc2)CCN(C(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC(N)=O)CC1 CHEMBL594526 IC50 0.11 nM
NC(=O)Cc1c(C(=O)N2CCC(O)(c3ccccc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL605109 IC50 0.11 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL111 EC50 0.11 nM
CCC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063235 Ki 0.11 nM
CCNC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063245 Ki 0.11 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4087520 Ki 0.11 nM
CCCCCn1/c(=N/C(=O)c2cccc3ccccc23)sc2ccccc21 CHEMBL4559193 Ki 0.11 nM
CCNC1(C(N)=O)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL562668 Ki 0.12 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncc(Br)c2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801350 Ki 0.12 nM
CC(C)OC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063244 Ki 0.12 nM
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL412262 pA2 0.1259 nM
CCCCS(=O)(=O)Oc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc(C(=O)NN3CCCCC3)c2C)cc1 CHEMBL4067800 pKi 0.1259 nM
Cc1ccc(NC(=O)c2nc(-c3ccc(Cl)cc3Cl)n(-c3ccc(OS(=O)(=O)CCC(F)(F)F)cc3)c2C)nc1 CHEMBL4089821 pKi 0.1259 nM
Cc1c(C(=O)Nc2ccc(C(F)(F)F)cn2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4068708 pKi 0.1259 nM
CC(C)(C)CC(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4248778 Ke 0.14 nM
Cc1ccc(C(c2ccc(Cl)cc2Cl)N2CCN(C(=O)NC3CCCCC3)CC2)cc1 CHEMBL1093735 Ki 0.15 nM
Cc1c(C(=O)NN2CC3CCCC3C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL418721 pA2 0.1585 nM
CCc1c(C(=O)NN2CCCCC2)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 CHEMBL583855 pA2 0.1585 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncnc2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801352 Ki 0.18 nM
C[C@@H](N[C@@H]1C[C@H](c2cccc(OCF)c2)N(c2ccc(C(F)(F)F)cc2)C1=O)c1ccccc1 CHEMBL494889 Kb 0.187 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NCCCO CHEMBL4172580 EC50 0.19 nM
CS/C(=N\S(=O)(=O)c1ccc(C(F)(F)F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL350924 pA2 0.1995 nM
CCCCNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)cc1)c1ccccc1S2 CHEMBL484952 pKi 0.1995 nM
CCCCNC(=O)c1ccc2c(c1)N=C(c1ccc(F)c(Cl)c1)c1ccccc1S2 CHEMBL520349 pKi 0.1995 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCCCC(F)(F)F)cc1 CHEMBL4086535 pKi 0.1995 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(C)C)cc1 CHEMBL4089947 pKi 0.1995 nM
Cc1c(C(=O)N[C@@H]2CCCC[C@H]2O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4090706 pKi 0.1995 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCCC#N)cc1OC2(C)C CHEMBL138917 Ki 0.2 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-c3nnc[nH]3)cc(C(F)(F)F)c2)CC1 CHEMBL529213 IC50 0.2 nM
S=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1093377 Ki 0.2 nM
Cc1c[nH]nc1C(=O)N[C@@H]1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1095158 IC50 0.2 nM
CC1(C)C[C@@H](NC(=O)c2cn[nH]c2)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1097841 IC50 0.2 nM
Cc1n[nH]c(C)c1C(=O)N[C@@H]1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1095151 IC50 0.2 nM
C[C@@H](O)C(=O)NC1CC2(CCCCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1083619 IC50 0.2 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncc(Cl)c2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801349 Ki 0.2 nM
Cc1ccc([C@@H](c2ccc(Cl)cc2Cl)N2CCN(C(=O)NC3CCCCC3)CC2)cc1 CHEMBL1910035 Ki 0.2 nM
CC(C)(C)CC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4469545 Ki 0.2 nM
CCCCCCC(C)(C)c1ccc([C@H]2C[C@@H](O)CC[C@@H]2CCCO)c(O)c1 CHEMBL2062131 EC50 0.2 nM
COc1cccc([C@H]2C[C@@H](N[C@H](C)c3ccc(F)cc3)C(=O)N2c2ccc(C(F)(F)F)cc2)c1 CHEMBL524047 Kb 0.216 nM
N#CCc1c(C(=O)N2Cc3ccc(Br)cc3C2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589162 IC50 0.22 nM
Cc1c(C(=O)Nc2ccc(OC(F)(F)F)cc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4093165 Ki 0.22 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL529436 Ki 0.23 nM
O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)c1ccno1 CHEMBL2063248 Ki 0.23 nM
CC(C)C(=O)NC1CCN(c2cnc(-c3ccc(C(F)(F)F)cc3)c(-c3ccncc3Cl)n2)CC1 CHEMBL497557 Ki 0.24 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL600602 Ki 0.24 nM
COC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063243 Ki 0.25 nM
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL1080545 pA2 0.2512 nM
CCCS(=O)(=O)Oc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc(C(=O)NN3CCCCC3)c2C)cc1 CHEMBL4065097 pKi 0.2512 nM
Cc1c(C(=O)NN2CCCC(O)C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4082908 pKi 0.2512 nM
O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)c1ccon1 CHEMBL2063247 Ki 0.26 nM
COCCN(C)C(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4463013 Ki 0.26 nM
Cc1c(C(=O)c2cccc3ccccc23)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL188 Log Ki 0.28 nM
NC(=O)C1(c2ccccc2)CCC(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL3957577 Ki 0.28 nM
COc1ncc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)s1 CHEMBL1801087 Ki 0.29 nM
CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12 CHEMBL1553629 IC50 0.29 nM
CCCCn1nc(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 CHEMBL5169682 Ki 0.299 nM
C[C@H](NC(=O)C(C)(C)Oc1cncc(C(F)(F)F)c1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL231636 IC50 0.3 nM
N/C(=N\S(=O)(=O)c1ccc(I)cc1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL460796 Ki 0.3 nM
CC(C(=O)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1)c1ccccc1 CHEMBL490024 EC50 0.3 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-c3ccn[nH]3)cc(C(F)(F)F)c2)CC1 CHEMBL487708 IC50 0.3 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-c3ncon3)cc(C(F)(F)F)c2)CC1 CHEMBL487500 IC50 0.3 nM
CC(C)Oc1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)[C@@H]3C[C@H]3c3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL523300 IC50 0.3 nM
NC(=O)Cc1c(C(=O)N2CCC(c3ncccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL593849 IC50 0.3 nM
Cc1cc(Cl)ccc1-c1nc2c(cc1-c1ccc(Cl)cc1)C(NC(=O)C(O)C(F)(F)F)CC(C)(C)O2 CHEMBL1169572 IC50 0.3 nM
Cc1n[nH]cc1C(=O)N[C@@H]1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1095150 IC50 0.3 nM
O=C(CO)NC1CC2(CCCCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1086494 IC50 0.3 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncc(O)c2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801346 Ki 0.3 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL2180214 Ke 0.3 nM
CC(C)(NC(=O)c1nn(Cc2ccc(F)cc2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354941 EC50 0.3 nM
O=C(NN1CCCCC1)c1cn(-c2ccc(Cl)cc2Cl)c(-c2ccc(C#Cc3ccc(C(F)(F)F)cc3)s2)c1CNS(=O)(=O)N1CCCC1 CHEMBL4644088 Ki 0.3 nM
CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL590799 AC50 0.3 nM
NC(=O)Cc1c(C(=O)N2CCC(Oc3cccc(F)c3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5394642 IC50 0.3 nM
N#Cc1ccc(CNC(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC(N)=O)cc1 CHEMBL5438290 IC50 0.3 nM
CC(NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL468313 pIC50 0.302 nM
Cc1c(C(=O)Nc2ccc(C(F)(F)F)nc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4066563 Ki 0.31 nM
CC1(C)Oc2cc(C3(CCCCCCC#N)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5071417 EC50 0.31 nM
N=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL160767 pA2 0.3162 nM
O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(N1CCCCC1)c1ccccc1S2 CHEMBL482566 pKi 0.3162 nM
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)[C@@H](c2ccccc2)C1 CHEMBL1080156 pA2 0.3162 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCCF)cc1 CHEMBL4105382 pKi 0.3162 nM
Cc1c(C(=O)N[C@H]2CCCC[C@H]2N)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4085407 pKi 0.3162 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)SCCS1 CHEMBL476325 Ki 0.32 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(I)cc1 CHEMBL285932 IC50 0.32 nM
COc1ccc(C(=O)c2c3n(c4ccccc24)C(CN2CCOCC2)CC3)cc1 CHEMBL28045 IC50 0.32 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C3CCCC3)cc1OC2(C)C CHEMBL252947 Ki 0.34 nM
N#CN1CCC(CNC(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC(N)=O)CC1 CHEMBL595462 IC50 0.34 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL5183968 Ki 0.35 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCC#N)cc1OC2(C)C CHEMBL336670 Ki 0.36 nM
Cc1c(-c2ccccc2)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4782654 EC50 0.36 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncc(F)c2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801348 Ki 0.37 nM
Cc1c(C(=O)NC2CCC(O)CC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4063825 Ki 0.37 nM
C[C@@H](NC(=O)C1(NC(=O)c2cn[nH]c2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801341 Ki 0.38 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1F CHEMBL4520650 Ki 0.38 nM
CN(C)C(=O)Nc1c(C(=O)C(C)(C)C)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL1090403 IC50 0.39 nM
Cc1cc(C)c(S(=O)(=O)NC(=N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)c(C)c1 CHEMBL156556 pA2 0.3981 nM
C/N=C(\NS(=O)(=O)c1c(C)cc(C)cc1C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL348174 pA2 0.3981 nM
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1 CHEMBL1081992 pA2 0.3981 nM
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL1081213 pA2 0.3981 nM
COc1ccc(OC(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760646 pKi 0.3981 nM
N=C(N)Cc1c(C(=O)NN2CCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL596164 IC50 0.4 nM
CC(C)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CO CHEMBL1091832 IC50 0.4 nM
C[C@H](O)C(=O)NC1CC2(CCCCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1084820 IC50 0.4 nM
Cc1c(C(=O)N2CCC(C(N)=O)(c3ccccc3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2030738 Ke 0.4 nM
CCCNC(=O)NC1(c2ccccc2)CCN(C(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)CC1 CHEMBL2030751 Ke 0.4 nM
CCCCNC(=O)NC1(c2ccccc2)CCN(C(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)CC1 CHEMBL2030753 Ke 0.4 nM
Cc1ccc(Cn2nc(C(=O)NC3C4(C)CCC(C4)C3(C)C)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL381689 Ki 0.4 nM
O=C(N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)C(F)(F)F CHEMBL4250064 Ke 0.4 nM
CC1(NC(=O)NC2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)CCC(F)(F)CC1 CHEMBL4454168 Ke 0.4 nM
C[C@@H]1C[C@](O)(c2cccc(F)c2)CCN1C(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC(N)=O CHEMBL5436186 IC50 0.4 nM
C[C@@H](NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC(N)=O)c1ccc(C(F)(F)F)nc1 CHEMBL5408564 IC50 0.4 nM
N#Cc1cccc(C2(O)CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)c1 CHEMBL5419851 IC50 0.4 nM
N#CCc1c(C(=O)NC2CCc3ccccc32)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589398 IC50 0.41 nM
C[C@@H](N[C@@H]1C[C@H](c2cccc(OCCF)c2)N(c2ccc(C(F)(F)F)cc2)C1=O)c1ccccc1 CHEMBL495092 Kb 0.424 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCBr)cc1OC2(C)C CHEMBL199561 Ki 0.43 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NCCO CHEMBL4161934 EC50 0.43 nM
CC1(C)Oc2cc(C3(CCCCCCCN=C=S)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5074603 EC50 0.43 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL5187099 Ki 0.43 nM
CC(C)(NC(=O)c1nn(CCCCCF)c2ccccc12)c1ccccc1 CHEMBL5219235 EC50 0.43 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CC1 CHEMBL19847 Log Ki 0.4365 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CCCC1 CHEMBL108868 Log Ki 0.4467 nM
O=S(=O)(CCCC(F)(F)F)Oc1cccc(Oc2cccc3c2C[C@H](CO)C3)c1 CHEMBL1668508 Ki 0.46 nM
Cc1ccnc(OC(C)(C)C(=O)N[C@@H](C)[C@@H](Cc2ccc(OCCF)cc2)c2cccc(C#N)c2)c1 CHEMBL226590 IC50 0.47 nM
Cc1cncc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)c1 CHEMBL1801345 Ki 0.47 nM
COc1cccc([C@H]2C[C@@H](N[C@H](C)c3ccccc3)C(=O)N2c2ccc(C(F)(F)F)cc2)c1 CHEMBL493873 Kb 0.472 nM
N#CCc1c(C(=O)NC2CCCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589884 IC50 0.49 nM
C[C@@H](NC(=O)C1(NC(=O)c2ccc(Br)nc2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801344 Ki 0.49 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL373626 IC50 0.5 nM
N#Cc1ccc(S(=O)(=O)/N=C(\N)N2C[C@H](c3ccccc3)C(c3ccc(Cl)cc3)=N2)cc1 CHEMBL459730 Ki 0.5 nM
O=C(CCc1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL489031 EC50 0.5 nM
O=C(Cc1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL514068 EC50 0.5 nM
N#Cc1ccc(CC(=O)N2CCN(S(=O)(=O)c3cc(Cl)cc(Cl)c3)CC2)cc1 CHEMBL515641 EC50 0.5 nM
O=C(C1CCCCC1)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL489429 EC50 0.5 nM
COc1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)[C@@H]3C[C@H]3c3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL490859 IC50 0.5 nM
O=C(Cc1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(C3CC3)cc(C(F)(F)F)c2)CC1 CHEMBL516900 IC50 0.5 nM
Cc1[nH]nc(C(=O)N[C@@H]2CC(C)(C)Oc3nc(-c4ccc(Cl)cc4Cl)c(-c4ccc(Cl)cc4)cc32)c1C CHEMBL1095476 IC50 0.5 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)OCCO1 CHEMBL108085 Ki 0.5 nM
CCCCCCNC(=O)NC1(c2ccccc2)CCN(C(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)CC1 CHEMBL2030748 Ke 0.5 nM
CC(C)[C@H](N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O CHEMBL2153670 IC50 0.5 nM
CC(C)(C)c1cc(NC(=O)[C@]2(C)CCCN2c2ccc(C(F)(F)F)cn2)no1 CHEMBL3400946 EC50 0.5 nM
CC(c1ccncc1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4229155 Ke 0.5 nM
CC(C)CS(=O)(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4238314 Ke 0.5 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(C(F)(F)F)nc2)CC1)c1ccccc1F CHEMBL4466325 Ke(app) 0.5 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccc(F)c(F)c1 CHEMBL4590762 Ke(app) 0.5 nM
NC(=O)Cc1c(C(=O)N2CCC(O)(c3cccc(F)c3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5437163 IC50 0.5 nM
NC(=O)Cc1c(C(=O)N2CCC(O)(c3ccccc3F)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5434468 IC50 0.5 nM
C/N=C(\NS(=O)(=O)c1ccc(C(F)(F)F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL345466 pA2 0.5012 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(C)(C)C)cc1 CHEMBL4068853 pKi 0.5012 nM
N#CCc1c(C(=O)NCc2ccc(Br)cc2F)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL607031 IC50 0.51 nM
NC(=O)Cc1c(C(=O)N2CCC(c3ccccc3F)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL596570 IC50 0.51 nM
Cc1ccc(C(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760652 pIC50 0.5129 nM
N#CCc1c(C(=O)NN2CCCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL606242 IC50 0.52 nM
COc1cncc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)c1 CHEMBL1801347 Ki 0.52 nM
CC1(C)Oc2cc(C3(CCCCCCN=C=S)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5092703 EC50 0.52 nM
N=C(Cc1c(C(=O)N2CCC(c3ccccc3F)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1)NO CHEMBL596376 IC50 0.54 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncs2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801086 Ki 0.54 nM
CS(=O)(=O)CC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063250 Ki 0.54 nM
Cc1ccncc1NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC(N)=O CHEMBL595234 IC50 0.55 nM
CCOCC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063242 Ki 0.56 nM
CC(C)(C)[C@@H](CO)NC(=O)c1nn(-c2cnccn2)c2c1C[C@@H]1CC[C@H]2O1 CHEMBL4871528 EC50 0.56 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C3CCCCC3)cc1OC2(C)C CHEMBL325389 Ki 0.57 nM
Cc1ccc(Cl)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760653 pIC50 0.5754 nM
CC(=O)Nc1c(C(=O)C(C)(C)C)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL1090402 IC50 0.58 nM
O=C(NNC(=S)Nc1ccc(Cl)c(Cl)c1)c1ccccc1O CHEMBL4476621 IC50 0.58 nM
N=C(N)Cc1c(C(=O)N2CCC(c3ncccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL605721 IC50 0.59 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(Br)c1 CHEMBL1209596 IC50 0.59 nM
Cc1nc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c(=O)n1CC(F)(F)F CHEMBL201602 Ki 0.6 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2ncn1CC(F)F CHEMBL201565 Ki 0.6 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@H]1CC=C(CO)C[C@H]21 CHEMBL334533 EC50 0.6 nM
CC1(C)CN(S(=O)(=O)c2cccc3ccccc23)CCN1C(=O)C1CCCCC1 CHEMBL525204 EC50 0.6 nM
O=C(C1CCCCC1)N1CCN(S(=O)(=O)c2cccc3ccccc23)CC1 CHEMBL523100 EC50 0.6 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-n3nccn3)cc(C(F)(F)F)c2)CC1 CHEMBL487091 IC50 0.6 nM
CC1(C)CC(NC(=O)C(F)(F)CO)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1095159 IC50 0.6 nM
CC1(C)C[C@@H](NC(=O)c2n[nH]c3ccccc23)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1095553 IC50 0.6 nM
CC1(C)C[C@@H](NC(=O)c2ccc3[nH]ncc3c2)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1095554 IC50 0.6 nM
O=S(=O)(CC1CCCCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4244624 Ke 0.6 nM
CCCCC(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4242001 Ke 0.6 nM
CCCCS(=O)(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4242477 Ki 0.6 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1F CHEMBL4567814 Ke(app) 0.6 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)OC1CCC1 CHEMBL4580498 Ki 0.6 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2cccnc2n(CCCCF)c1=O CHEMBL5198892 Ki 0.6 nM
CCCCNc1ccc(C(=O)OCCN(C)C)cc1 CHEMBL698 AC50 0.6 nM
Cn1c(=O)c2c(ncn2C)n(C)c1=O CHEMBL113 AC50 0.6 nM
O=C1CN=C(c2ccccc2)c2cc(Cl)ccc2N1 CHEMBL523 AC50 0.6 nM
CC(C)c1noc(C2(O)CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)n1 CHEMBL5400150 IC50 0.6 nM
CC(C)(C)c1nc(-c2ccc(F)cc2)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 CHEMBL512422 IC50 0.63 nM
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL578421 pA2 0.631 nM
CCCCCC1=NN(C(=O)N[C@H]2C[C@H]3CC[C@]2(C)C3(C)C)CC1c1ccccc1 CHEMBL1223588 pEC50 0.631 nM
Cc1ccc(C)c(Cn2c(C(=O)NCC(C)(C)CO)cc3cc(C#N)ccc32)c1 CHEMBL1760654 pIC50 0.631 nM
C[C@@H](NC(=O)C1(NC(=O)c2ccnnc2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801351 Ki 0.65 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(Cl)cc3)c(-c3ccnc(Cl)c3)n2)CC1 CHEMBL496507 Ki 0.67 nM
COc1cc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)on1 CHEMBL1801085 Ki 0.67 nM
Cc1c(C(=O)NC2CCN(C(=O)C(F)(F)F)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL3758534 Ke 0.67 nM
Cc1ccc(OC(C)(C)C(=O)N[C@@H](C)[C@@H](Cc2ccc(OCCF)cc2)c2cccc(C#N)c2)nc1 CHEMBL226591 IC50 0.7 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-n3cccn3)cc(C(F)(F)F)c2)CC1 CHEMBL487090 IC50 0.7 nM
CC(F)(F)CN1CCc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL483543 Ki 0.7 nM
CCC(F)(F)CN1CCOc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL520345 Ki 0.7 nM
N#CCc1c(C(=O)NCc2ccc(F)c(Br)c2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL590387 IC50 0.7 nM
CC1(C)CC(NC(=O)C(C)(O)C(F)(F)F)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1097455 IC50 0.7 nM
CC1(C)CC(NC(=O)CC(O)C(F)(F)F)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1097456 IC50 0.7 nM
CC(C)(O)C(=O)NC1CC2(CCCCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1085566 IC50 0.7 nM
Cc1c(C(=O)N2CCC(NC(=O)NC(C)C)(c3ccccc3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2030749 Ke 0.7 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL2180213 Ke 0.7 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccc(F)c(F)c1 CHEMBL4532772 Ke(app) 0.7 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(OC(F)F)nc2)CC1)c1ccccc1F CHEMBL4440527 Ke(app) 0.7 nM
CS/C(N)=N/C(=N/S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5070349 Ki 0.7 nM
N#Cc1ccc(C2(O)CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)cc1 CHEMBL5416610 IC50 0.7 nM
C[C@@H]1CC(O)(c2ccccc2F)C[C@H](C)N1C(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC(N)=O CHEMBL5412598 IC50 0.7 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CC1(Br)Br CHEMBL118631 Log Ki 0.7079 nM
Cc1nnsc1C(=O)NC1(C(=O)N[C@H](C)c2ccc(-n3nc(Cl)c4ccccc43)cc2F)CC1 CHEMBL1801340 Ki 0.71 nM
CCCCCCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL338484 Ki 0.73 nM
Cc1ccc(OC(C)(C)C(=O)N[C@@H](C)[C@@H](Cc2ccc(OCC[18F])cc2)c2cccc(C#N)c2)nc1 CHEMBL226642 IC50 0.73 nM
CC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063122 Ki 0.75 nM
COc1ccc(C)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760651 pIC50 0.7586 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCC(C)C(=O)NCCF CHEMBL309042 Log Ki 0.76 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL159611 Kd 0.77 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL411626 Ki 0.77 nM
CC1=CCC2C(C1)c1c(O)cc(C/C=C/CCCC#N)cc1OC2(C)C CHEMBL162079 Kd 0.77 nM
CCCCCCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL124194 Ki 0.77 nM
C[C@H](NC(=O)C(C)(C)Oc1cc(C(F)(F)F)ccn1)[C@@H](Cc1ccc(OCCF)cc1)c1cccc(C#N)c1 CHEMBL376794 IC50 0.77 nM
COc1ccc(Br)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760650 pIC50 0.7762 nM
N=C(N)Cc1c(C(=O)NCc2ccc(F)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL595946 IC50 0.79 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL5194443 Ki 0.79 nM
Cc1c(Br)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4753891 Ki 0.79 nM
C/N=C(\NS(=O)(=O)c1cccc(C(F)(F)F)c1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL157591 pA2 0.7943 nM
Cc1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL175650 pA2 0.7943 nM
Cc1c(C(=O)NC2CCCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL176022 pA2 0.7943 nM
Cc1c(C(=O)NC2CC3CCC2C3)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL177393 pA2 0.7943 nM
Cc1ccc(C(=O)Oc2cccc3cccnc23)cc1S(=O)(=O)N1CCCCC1 CHEMBL245876 Log IC50 0.7943 nM
O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(N1CCC(F)(F)CC1)c1ccccc1S2 CHEMBL482567 pKi 0.7943 nM
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1 CHEMBL1081993 pA2 0.7943 nM
CC(C)(CO)CNC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1 CHEMBL1760645 pKi 0.7943 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCCC(F)(F)F)cc1 CHEMBL4076020 pKi 0.7943 nM
CCCC(C)(C)c1ccc2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL371214 Ki 0.797 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(Cl)cn1)[C@@H](Cc1ccc(OCCF)cc1)c1cccc(C#N)c1 CHEMBL226589 IC50 0.8 nM
CCC(=O)NC1CCN(c2cnc(-c3ccc(C(F)(F)F)cc3)c(-c3ccncc3Cl)n2)CC1 CHEMBL524804 Ki 0.8 nM
CC(C)CN(C)C(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4466640 Ki 0.8 nM
CCN(CC)S(=O)(=O)/N=C(/N=C(/C)N)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5085017 IC50 0.8 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL5200844 Ki 0.8 nM
COc1cc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(Br)c5ccccc54)cc3F)CC2)on1 CHEMBL1801076 Ki 0.81 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(CO)C[C@@H]21 CHEMBL70625 Ki 0.82 nM
CC(F)(F)CN1CCOc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL484929 Ki 0.82 nM
NC(=O)Cc1c(C(=O)NN2CCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL605108 IC50 0.82 nM
O=S1(=O)CCN(c2cnc(-c3ccc(C(F)(F)F)cc3)c(-c3ccncc3Cl)n2)CC1 CHEMBL496091 Ki 0.83 nM
COc1ccc(NC(=O)c2ccc(Cn3ccnn3)c3ccccc23)c(C(=O)NCC2CCCCC2)n1 CHEMBL2316376 IC50 0.85 nM
CCc1ccc(/C=C2\C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 CHEMBL4483714 Ki 0.859 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCC(=O)N(C)C)cc1OC2(C)C CHEMBL344455 Ki 0.86 nM
CCCCC/C=C/c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL161874 Kd 0.86 nM
CCCCC/C=C/c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL395230 Activity 0.86 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(C(F)(F)F)cc3)c(-c3ccnc(Cl)c3)n2)CC1 CHEMBL496508 Ki 0.87 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)C1CCCC1 CHEMBL2436760 Ke 0.89 nM
CCc1c(C(=O)N[C@H]2CCCC[C@@H]2O)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 CHEMBL230800 Kb 0.9 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(OCCF)cc1)c1cccc(C#N)c1 CHEMBL226534 IC50 0.9 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(OCCF)cc1)c1cc(F)cc(C#N)c1 CHEMBL376767 IC50 0.9 nM
COc1ccc(C[C@@H](c2cc(F)cc(C#N)c2)[C@H](C)NC(=O)C(C)(C)Oc2ccc(C(F)(F)F)cn2)cc1 CHEMBL226684 IC50 0.9 nM
CCOc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(=O)(=O)C(F)(F)F)cc2)c(S(=O)(=O)c2ccccc2F)c1 CHEMBL245782 Ki 0.9 nM
O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1cnc2ccc(Cl)cc2c1 CHEMBL526345 EC50 0.9 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cc(C(C)(C)C)no1 CHEMBL481508 Ki 0.9 nM
C[C@H](NC(=O)C(C)(C)Nc1cc(C(F)(F)F)ccn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL567679 EC50 0.9 nM
Fc1ccccc1CN1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4225409 Ke 0.9 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(Cc5cccc(Cl)c5)CC4)ncnc32)cc1 CHEMBL4225147 Ki 0.9 nM
CCCN(C)C(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4524602 Ki 0.9 nM
O=C(NCC1CCCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4567690 Ki 0.9 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1cc(F)cc(F)c1 CHEMBL246930 IC50 0.91 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)n2)CC1 CHEMBL496293 Ki 0.91 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCF CHEMBL74909 Log Ki 0.93 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C3CCCCCC3)cc1OC2(C)C CHEMBL252949 Ki 0.94 nM
COc1ccc(NC(=O)c2ccc(Cn3ccnn3)c3ccccc23)c(C(=O)NCC2CCC2)n1 CHEMBL2316377 IC50 0.97 nM
CCCCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL306529 Log Ki 0.98 nM
N=C(NS(=O)(=O)c1ccc(F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL158502 pA2 1.0 nM
C/N=C(\NS(=O)(=O)c1ccc(C(F)(F)F)cc1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL156264 pA2 1.0 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL109393 Ki 1.0 nM
CCc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL426585 pA2 1.0 nM
O=C1C2N=C(c3ccccc3Cl)N(c3ccc(Cl)cc3)C2N=CN1CC(F)(F)F CHEMBL201520 Ki 1.0 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2ccn1CC(F)(F)F CHEMBL379246 Ki 1.0 nM
CCc1nc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c(=O)n1CC(F)(F)F CHEMBL425762 Ki 1.0 nM
O=C(NN1CCCCC1)c1cnc(-c2ccc(Br)cc2)c(-c2ccc(Br)cc2)n1 CHEMBL226222 IC50 1.0 nM
O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1F)(c1ccc(F)cc1F)O2)N1CCCCC1 CHEMBL410339 Ki 1.0 nM
COC(=O)c1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)Cc3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL478696 EC50 1.0 nM
O=C(Cc1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(Br)cc(C(F)(F)F)c2)CC1 CHEMBL476254 EC50 1.0 nM
O=C(Cc1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 CHEMBL476253 EC50 1.0 nM
O=C(C1CCCCC1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 CHEMBL489425 EC50 1.0 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1nc(C(C)(C)C)cs1 CHEMBL511790 Ki 1.0 nM
CCC(CC)(CC)c1cc(/N=C2\OCC3(CCCCC3)CN2C(=S)SC)on1 CHEMBL519288 Ki 1.0 nM
CC(C)(C)c1nc2nc(-c3ccc(C#N)cc3Cl)c(-c3ccc(Cl)cc3)cc2c2n[nH]c(=O)n12 CHEMBL467329 IC50 1.0 nM
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CCC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL577384 pA2 1.0 nM
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1CCC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL574172 pA2 1.0 nM
CC(C)(O)CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL569547 pA2 1.0 nM
N#CCc1c(C(=O)N2CCC(c3ccc(F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL590380 IC50 1.0 nM
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1 CHEMBL1081305 pA2 1.0 nM
CN/C(=N\S(=O)(=O)N1CCC(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL1076636 pA2 1.0 nM
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL1080916 pA2 1.0 nM
CSc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1088245 pA2 1.0 nM
CSc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL1088221 pA2 1.0 nM
Cc1cc(C(=O)N[C@@H]2CC(C)(C)Oc3nc(-c4ccc(Cl)cc4Cl)c(-c4ccc(Cl)cc4)cc32)n[nH]1 CHEMBL1096182 IC50 1.0 nM
O=C1CCCN1C1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063252 Ki 1.0 nM
CCCCn1c2c(cc(C(=O)NC(C)(C)c3ccccc3)c1=O)CCCCCC2 CHEMBL2387185 Ki 1.0 nM
Cc1c(C(=O)NN2CCS(=O)(=O)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CCCC#N)cc1 CHEMBL3341898 Ki 1.0 nM
Fc1ccc(CN2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cc1 CHEMBL4225999 Ke 1.0 nM
Clc1ccc(CN2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cc1 CHEMBL4225421 Ki 1.0 nM
CC(C)S(=O)(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4244992 Ke 1.0 nM
CCCCCn1/c(=N/C(=O)c2cccc(C(F)(F)F)c2)sc2ccccc21 CHEMBL4592199 Ki 1.0 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(C(F)(F)F)nc2)CC1)c1ccc(F)c(F)c1 CHEMBL4553438 Ke(app) 1.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)cc2)cc1)c1cc2ccccc2[nH]1 CHEMBL4522563 IC50 1.0 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)C(F)(F)F CHEMBL2436766 Ke 1.05 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccs3)cc1OC2(C)C CHEMBL519575 Ki 1.08 nM
C[C@H](NC(=O)C(C)(C)Oc1cc(F)cc(F)c1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL219480 IC50 1.1 nM
Cc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(=O)(=O)C(F)(F)F)cc2)c(S(=O)(=O)c2ccccc2F)c1 CHEMBL245981 Ki 1.1 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCCCC4)ncnc32)cc1 CHEMBL522235 Ki 1.1 nM
Cc1cc(C)cc(S(=O)(=O)N2CCN(C(=O)C3CCCCC3)CC2)c1 CHEMBL522930 EC50 1.1 nM
CC(C)c1nc(OCc2ncon2)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 CHEMBL466110 IC50 1.1 nM
CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(C(F)(F)F)cc3)cc2c2n[nH]c(=O)n12 CHEMBL467914 IC50 1.1 nM
N=C(Cc1c(C(=O)Nc2ccc(F)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1)NO CHEMBL595232 IC50 1.1 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccc(Oc3ccccc3)cc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1091814 Ki 1.1 nM
CC1(C)C[C@@H](NC(=O)CC(O)(C(F)(F)F)C(F)(F)F)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1095211 IC50 1.1 nM
Cc1ccc([C@H](c2ccc(Cl)cc2Cl)N2CCN(C(=O)NC3CCCCC3)CC2)cc1 CHEMBL1910034 Ki 1.1 nM
CC(c1ccccc1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4227354 Ki 1.1 nM
CCCN(CC(F)(F)F)C(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4578966 Ki 1.1 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL4472410 Ke(app) 1.1 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL4445915 Ke(app) 1.1 nM
CCCCCCC(C)(C)c1cc(OC)cc(OCCCCCCCC(=O)NC2CC2)c1 CHEMBL4647981 Ki 1.1 nM
CC(C)(C)/C(N)=N/C(=N/S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5076792 Ki 1.1 nM
Cc1c(Cl)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4781952 EC50 1.12 nM
CC(NC(=O)C(C)(C)Oc1cc(F)cc(F)c1)C(Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL511245 pIC50 1.122 nM
CCCCn1nc(C(=O)N[C@H](C(N)=O)C(C)C)c2ccccc21 CHEMBL5180182 pKi 1.175 nM
CCCc1ccc(/C=C2\C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 CHEMBL4443660 Ki 1.18 nM
CC1=CCC2C(C1)c1c(O)cc(CC#CCCCBr)cc1OC2(C)C CHEMBL163430 Kd 1.2 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCC(=O)NN3CCCCC3)cc1OC2(C)C CHEMBL138772 Ki 1.2 nM
O=C(c1cc2c(cc1F)OC(c1ccccc1)(c1ccccc1)O2)N1CCCCC1 CHEMBL260625 EC50 1.2 nM
CCNC1(C(N)=O)CN(c2cnc(-c3ccc(C(F)(F)F)cc3)c(-c3ccnc(Cl)c3)n2)C1 CHEMBL498783 Ki 1.2 nM
CCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL462070 IC50 1.2 nM
CCCC#Cc1ccc(-c2c(CC)c(C(=O)NN3CCCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL460987 IC50 1.2 nM
CCCC#Cc1ccc(-c2c(CC)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL460986 IC50 1.2 nM
Cc1c(C(=O)NN2CCCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CCC(C)C)s1 CHEMBL462686 IC50 1.2 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CCC(C)C)s1 CHEMBL460343 IC50 1.2 nM
CCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CCCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL460132 IC50 1.2 nM
COC(=O)C(Cc1ccccc1)NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC#N CHEMBL590132 IC50 1.2 nM
N#CCc1c(C(=O)NCc2ccc(Cl)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL590136 IC50 1.2 nM
N#CCc1c(C(=O)NCc2ccc(Br)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589651 IC50 1.2 nM
N#Cc1ccc(N2CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)nc1 CHEMBL605522 IC50 1.2 nM
NC(=O)Cc1c(C(=O)NC2CCN(C(=O)C3CC3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL594280 IC50 1.2 nM
O=C(NN1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1093078 Ki 1.2 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccc(C(F)(F)F)cc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1084429 Ki 1.2 nM
CNCC(=O)Nc1c(C(=O)C(C)(C)C)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL1090404 IC50 1.2 nM
CC(C)(C)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CO CHEMBL1089032 IC50 1.2 nM
CC(=O)N[C@@H]1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1095990 IC50 1.2 nM
CCCCCCC(C)(C)c1ccc2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL1277685 Ki 1.2 nM
C[C@@H](NC(=O)C1(NC(=O)c2cncc(Cl)n2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801354 Ki 1.2 nM
CCCCCn1cc(C(=O)c2ccc(Br)c3ccccc23)c2ccccc21 CHEMBL2206834 Ki 1.2 nM
O=c1cc(NC2CCN(S(=O)(=O)C(F)(F)F)CC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3945880 EC50 1.2 nM
CCCS(=O)(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4248795 Ki 1.2 nM
O=S(=O)(CCC(F)(F)F)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4238756 Ki 1.2 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)N1CCCCC1 CHEMBL4450173 Ki 1.2 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccc(F)cc1F CHEMBL4441517 Ke(app) 1.2 nM
CN(C)c1ccc(CCNC(=O)c2[nH]c3ccc(Cl)cc3c2CN=[N+]=[N-])cc1 CHEMBL4797581 EC50 1.2 nM
CC(C)(C)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CC1CCC2O1 CHEMBL4845707 EC50 1.2 nM
CCCCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL5171161 Ki 1.2 nM
Nc1c(Br)cc(Br)cc1CN[C@H]1CC[C@H](O)CC1 CHEMBL153479 AC50 1.2 nM
CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 CHEMBL191 AC50 1.2 nM
CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 CHEMBL1014 AC50 1.2 nM
Cc1c(C(=O)NC2CCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL368547 pA2 1.259 nM
Cc1c(C(=O)NCc2ccc(C(F)(F)F)cc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL178799 pA2 1.259 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)c1CF CHEMBL177990 pA2 1.259 nM
C/N=C(\NS(=O)(=O)N1CCCCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL197040 pA2 1.259 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CC1(Cl)Cl CHEMBL120669 Log Ki 1.259 nM
Cc1ccc(C(=O)Oc2cccc3cccnc23)cc1S(=O)(=O)N1CCOCC1 CHEMBL245878 Log IC50 1.259 nM
CC(C)CNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)s1)c1ccccc1S2 CHEMBL485181 pKi 1.259 nM
CSc1c(C(=O)NN2CCCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL1088507 pA2 1.259 nM
COc1cccc2c(C(=O)N3C[C@@H](C)N(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 CHEMBL1209708 pKi 1.259 nM
CCCCCn1cc(C(=O)Nc2cccc3ccccc23)c2ccccc21 CHEMBL1828805 pKi 1.259 nM
COc1cccc2c(C(=O)N3C[C@@H](C)N(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 CHEMBL3347370 pKi 1.259 nM
COc1cccc2c(C(=O)N3CCN(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 CHEMBL3347369 pKi 1.259 nM
CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL2348462 EC50 1.29 nM
CC1=CCC2C(C1)c1c(O)cc(CCCCC(F)(F)F)cc1OC2(C)C CHEMBL74662 Log Ki 1.3 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL367819 IC50 1.3 nM
COC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL179901 IC50 1.3 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(Cl)cn1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL387027 IC50 1.3 nM
C[C@H](NC(=O)C(C)(C)Oc1ccccn1)[C@@H](Cc1ccc(OCCF)cc1)c1cccc(C#N)c1 CHEMBL227329 IC50 1.3 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL382728 Ki 1.3 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(O)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL245961 Ki 1.3 nM
CCCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CC4CCCC4C3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL461429 IC50 1.3 nM
O=C(c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(C3CC3)cc(C(F)(F)F)c2)CC1 CHEMBL522114 EC50 1.3 nM
CC(C)N1CCOc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL482741 Ki 1.3 nM
N=C(Cc1c(C(=O)NN2CCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1)NO CHEMBL595017 IC50 1.3 nM
CC1(C)C[C@@H](NC(=O)c2ccccc2N)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1094840 IC50 1.3 nM
CC1(C)C[C@@H](NC(=O)c2cccc3[nH]ncc23)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1097795 IC50 1.3 nM
CC(=O)NC1CC2(CCCCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1086493 IC50 1.3 nM
CCCCCn1c(C)c(C(=O)c2ccc(CCC)c3ccccc23)c2ccccc21 CHEMBL564901 Ki 1.3 nM
COc1cc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(C)c5ccccc54)cc3F)CC2)on1 CHEMBL1801072 Ki 1.3 nM
CCN1C(=O)OC2(CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)C1=O CHEMBL5418694 IC50 1.3 nM
CC(NC(=O)C(C)(C)Oc1ccc(Cl)cn1)C(Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL513814 pIC50 1.318 nM
COc1ccc(C(F)(F)F)cc1Cn1c(C(=O)NCC2(CO)CC2)cc2cc(C#N)ccc21 CHEMBL1760657 pIC50 1.318 nM
CCCCn1cc(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 CHEMBL5202843 Ki 1.34 nM
CCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccccc1 CHEMBL360763 IC50 1.4 nM
CCCc1c(C(=O)N[C@H]2CCCC[C@@H]2O)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 CHEMBL230801 Kb 1.4 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(C3CC3)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL245983 Ki 1.4 nM
CCCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL461428 IC50 1.4 nM
CC1(C)C[C@@H](NC(=O)c2n[nH]c3c2CCC3)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1097840 IC50 1.4 nM
CS(=O)(=O)NCCCn1c(C(=O)N2CCC(C(N)=O)(N3CCC(F)(F)CC3)CC2)cc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1210782 IC50 1.4 nM
Cc1ccc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)cn1 CHEMBL1801343 Ki 1.4 nM
COCC(=O)NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063241 Ki 1.4 nM
O=C(NCC1CCC1)c1ncccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12 CHEMBL2316387 EC50 1.4 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccc(C#N)cc3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260745 Ki 1.4 nM
Cc1c(Br)cn(Cc2ccc(F)cc2)c(=O)c1C(=O)NC1CCCCCC1 CHEMBL4164954 EC50 1.4 nM
O=C(NC1CCCCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4246283 Ki 1.4 nM
O=C(NC1CCCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4533562 Ki 1.4 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCC(Nc5ccccc5)CC4)ncnc32)cc1 CHEMBL4475060 Ke(app) 1.4 nM
O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2ccc[nH]2)c1 CHEMBL4450500 Kd 1.4 nM
CC1(C)Oc2cc(C3(CCCCCC#N)CCC3)cc(O)c2[C@@H]2CC(=O)CC[C@H]21 CHEMBL5203712 EC50 1.4 nM
CCCCCn1cc(C(=O)c2cccc3c2CC(C)(C)C3)c2ccccc21 CHEMBL4860950 Ki 1.46 nM
O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1 CHEMBL3341861 IC50 1.47 nM
COc1ccc(C(F)(F)F)cc1Cn1c(C(=O)NCCC2(O)CCC2)cc2cc(C#N)ccc21 CHEMBL1760668 pIC50 1.479 nM
COc1ccc(C(C)(C)C)cc1Cn1c(C(=O)NCC2(CO)CC2)cc2cc(C#N)ccc21 CHEMBL1760658 pIC50 1.479 nM
O=C(NCCF)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL362192 IC50 1.5 nM
C[C@H](NC(=O)C(C)(C)Oc1cccc(Cl)c1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL385033 IC50 1.5 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCOc3ccc(C#N)cc3)cc1OC2(C)C CHEMBL136120 Ki 1.5 nM
Clc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc3c(NC4CCCCC4)ncnc32)cc1 CHEMBL524087 Ki 1.5 nM
CN1CCN(c2ncnc3c2nc(-c2ccc(Cl)cc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL498411 Ki 1.5 nM
CC(C(=O)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1)c1ccc(C(F)(F)F)cc1 CHEMBL489437 EC50 1.5 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(C(O)C(F)(F)F)cc(C(F)(F)F)c2)CC1 CHEMBL520543 IC50 1.5 nM
O=C1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2OCCN1CC(F)(F)F CHEMBL482742 Ki 1.5 nM
N=C(N)Cc1c(C(=O)Nc2ccc(F)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL605313 IC50 1.5 nM
C[C@@H](NC(=O)C1(NC(=O)c2cccnc2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F CHEMBL1801342 Ki 1.5 nM
COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1 CHEMBL413775 Ki 1.5 nM
CN(Cc1ccccc1)C(=O)N1CC(O[C@H](c2ccc(Cl)cc2)c2cccnc2Cl)C1 CHEMBL1952279 Ki 1.5 nM
CC(C)(C)OC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2180205 Ki 1.5 nM
CC(C(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL4249388 Ke 1.5 nM
CCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL2387541 Ki 1.5 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2cccnc2n(Cc2ccc(F)cc2)c1=O CHEMBL5186632 Ki 1.5 nM
CC(NC(=O)C(C)(C)Oc1cccc(Cl)c1)C(Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL466244 pIC50 1.514 nM
CCCOc1cccc(Cn2c(C(=O)NCC(C)(C)CO)cc3cc(C#N)ccc32)c1 CHEMBL1760655 pIC50 1.549 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc([Si](C)(C)CCCCCC)cc1O CHEMBL5204553 Ki 1.56 nM
C/N=C(\NS(=O)(=O)N1CCSCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL383580 pA2 1.585 nM
CC(C)CCNC(=O)c1ccc2c(c1)N=C(c1ccccn1)c1ccccc1S2 CHEMBL520509 pKi 1.585 nM
CN/C(=N\S(=O)(=O)N1CCC(F)(F)CC1)C1=NN(c2ccc(Cl)cc2)[C@@H](c2ccccc2)C1 CHEMBL1082018 pA2 1.585 nM
CSc1c(C(=O)NN2CCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1088244 pA2 1.585 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)c1I CHEMBL1088220 pA2 1.585 nM
O=C(c1cn2c3c(cccc13)OC[C@H]2C1CCCCC1)N1CCN2CCCC[C@H]2C1 CHEMBL1287847 pKi 1.585 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(Br)c3)cc1OC2(C)C CHEMBL487464 Ki 1.59 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL465 Log Ki 1.6 nM
C[C@H](NC(=O)C(C)(C)Oc1cccc(F)c1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL385767 IC50 1.6 nM
CN1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL496555 Ki 1.6 nM
C[C@H]1CC[C@H](NC(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC#N)CC1 CHEMBL599964 IC50 1.6 nM
N#CCc1c(C(=O)NCc2ccc(Cl)cc2Cl)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589893 IC50 1.6 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1088728 Ki 1.6 nM
CCc1nc(C(F)(F)F)ccc1Cn1c(=O)c(-c2ccc(C#N)cc2)c(-c2ccc(Cl)cc2)c2nn(CC)c(=O)n21 CHEMBL3260747 Ki 1.6 nM
CC1(NC(=O)Nc2ccccc2F)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4535004 Ke 1.6 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(OC(F)F)nc2)CC1)c1ccc(F)c(F)c1 CHEMBL4475337 Ke(app) 1.6 nM
CCCCCn1nc(C(=O)N[C@@H](C(=O)OC)C(C)C)cc1C(C)(C)C CHEMBL4791449 EC50 1.6 nM
C/C(N)=N\C(=N\S(=O)(=O)N1CCCCC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5093228 Ki 1.6 nM
CC1=CCC2C(C1)c1c(O)cc(C/C=C/CCCBr)cc1OC2(C)C CHEMBL162746 Kd 1.66 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)n2)CC1 CHEMBL522720 Ki 1.66 nM
CCCCCn1cc(C(=O)N[C@H](C(=O)OC)C(C)(C)C)c2cccnc21 CHEMBL4474071 pEC50 1.698 nM
CCCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL425163 IC50 1.7 nM
CCCCCCC(C)(C)c1ccc(-c2ccccc2OC)c(O)c1 CHEMBL234678 Ki 1.7 nM
CCCCCCC(C)(C)c1ccc(-c2c(C)cccc2C)c(O)c1 CHEMBL232410 Ki 1.7 nM
Clc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc3c(NN4CCCCC4)ncnc32)cc1 CHEMBL496770 Ki 1.7 nM
Clc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc3c(N4CCCCC4)ncnc32)cc1 CHEMBL496352 Ki 1.7 nM
CCCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CCCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL522522 IC50 1.7 nM
O=C1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CCN1CC(F)(F)F CHEMBL485538 Ki 1.7 nM
N#CCc1c(C(=O)N[C@H]2c3ccccc3C[C@H]2O)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL592526 IC50 1.7 nM
NC(=O)Cc1c(C(=O)NN2CCOCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL594756 IC50 1.7 nM
CC(C)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1N CHEMBL1091692 IC50 1.7 nM
CC1(C)CC(NC(=O)C(C)(C)O)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1094847 IC50 1.7 nM
O=C1CC(c2cccc(F)c2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1084555 IC50 1.7 nM
CC1(C)CC(NC(=O)CO)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1083014 IC50 1.7 nM
CC1(C)CC(NC(=O)CCO)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1083025 IC50 1.7 nM
COC(=O)C(C)(C)NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2018655 Ki 1.7 nM
CCCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccc(C#N)cc3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3259829 Ki 1.7 nM
O=[N+]([O-])CC(c1ccccc1F)c1c(-c2cccc(F)c2)[nH]c2c(F)cccc12 CHEMBL4519310 EC50 1.7 nM
CC(C)(C)OCCC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4468164 Ke(app) 1.7 nM
CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353439 Ki 1.7 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(F)cc3)c(-c3ccc(Cl)cc3Cl)n2)CC1 CHEMBL496919 Ki 1.75 nM
CC1=CCC2C(C1)c1c(O)cc(CCCCCF)cc1OC2(C)C CHEMBL75330 Log Ki 1.76 nM
CCCc1ccc(C(C)(C)c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)cc1 CHEMBL471122 Ki 1.77 nM
NC(=O)C1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2180215 Ki 1.79 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1cc(F)cc(F)c1 CHEMBL180360 IC50 1.8 nM
CC(C)NC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL361020 IC50 1.8 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2ncn1CCC(F)(F)F CHEMBL204339 Ki 1.8 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL15874 Ki 1.8 nM
C[C@H](NC(=O)C(C)(C)Oc1ccccn1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL374791 IC50 1.8 nM
C[C@H](NC(=O)C(C)(C)Oc1cc(C(F)(F)F)ncn1)[C@@H](Cc1ccc(OCCF)cc1)c1cccc(C#N)c1 CHEMBL226640 IC50 1.8 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C#N)cn1)[C@@H](Cc1ccc(OCCF)cc1)c1cccc(C#N)c1 CHEMBL387526 IC50 1.8 nM
CCCCCCC1(c2ccc(-c3cc(C)cc(C)c3)c(O)c2)CCCCC1 CHEMBL233636 Ki 1.8 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)SCCCS1 CHEMBL108392 Ki 1.8 nM
N#CCc1c(C(=O)NN2CCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL596163 IC50 1.8 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Br)cc2F)CC1 CHEMBL1087251 Ki 1.8 nM
C[C@@H](O)NC(=O)C1CC(C)(C)N(C)c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1082650 IC50 1.8 nM
NC(=O)Cc1c(C(=O)N2CCC(O)(c3ccc(F)cn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL596167 IC50 1.8 nM
C=C1CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCCC)cc1OC2(C)C CHEMBL57802 Ki 1.82 nM
CCc1ccc(C(C)(C)c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)cc1 CHEMBL471297 Ki 1.85 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C3(C4CCCCC4)SCCS3)cc1OC2(C)C CHEMBL117033 Ki 1.86 nM
CCCCOc1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)cc1C(=O)OC CHEMBL425870 IC50 1.9 nM
CCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL360104 IC50 1.9 nM
Cc1ccc(-n2cc(C(=O)NC3CCCCC3)nc2-c2ccc(Cl)cc2Cl)cc1 CHEMBL390543 Ki 1.9 nM
CC(C)(C)c1nc(N2CCNCC2)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 CHEMBL466685 IC50 1.9 nM
CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c2n[nH]c(=O)n12 CHEMBL466711 IC50 1.9 nM
C[C@H](NC(=O)C(C)(C)Nc1cc2ccccc2cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL572097 EC50 1.9 nM
N#CCc1c(C(=O)NC2CCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL602506 IC50 1.9 nM
N=C(N)Cc1c(C(=O)N2CCC(O)(c3ccc(F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL605106 IC50 1.9 nM
NC(=O)Cc1c(C(=O)N2CCC(O)(c3ccccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL596166 IC50 1.9 nM
CC(C)C(=O)c1oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2c1N CHEMBL1089338 IC50 1.9 nM
CC(C)(C)C1CC(=O)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2O1 CHEMBL1086013 IC50 1.9 nM
CCN(CC(=O)NC1CC1)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1 CHEMBL2029727 EC50 1.9 nM
Cc1nc(C(F)(F)F)ccc1Cn1c(=O)c(-c2ccc(C#N)cc2)c(-c2ccc(Cl)cc2)c2nn(C(C)C)c(=O)n21 CHEMBL3260748 Ki 1.9 nM
CCN(CC)S(=O)(=O)/N=C(/N=C(/C)N)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5090020 IC50 1.9 nM
CC(C)S(=O)(=O)N1CCC(NC(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC(N)=O)CC1 CHEMBL5404907 IC50 1.9 nM
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL158784 pIC50 1.905 nM
O=C(CC1CCCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2436758 Ki 1.93 nM
CCCCCn1ccc(C(=O)c2cccc3ccccc23)c1 CHEMBL71810 Log Ki 1.94 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO CHEMBL15848 Log Ki 1.95 nM
CC(=O)NC1CCN(c2cnc(-c3ccc(C(F)(F)F)cc3)c(-c3ccncc3Cl)n2)CC1 CHEMBL497556 Ki 1.97 nM
C/N=C(\NC(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL158700 pA2 1.995 nM
COc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc(C(=O)NN3CCCCC3)c2C)cc1 CHEMBL175369 pA2 1.995 nM
Cc1c(C(=O)NN2CCCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL175478 pA2 1.995 nM
CCN(CC)S(=O)(=O)N/C(=N\C(C)C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL194566 pA2 1.995 nM
CN/C(=N\S(=O)(=O)N1CCCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL195958 pA2 1.995 nM
CN/C(=N\S(=O)(=O)N1CCCCC1)N1C[C@H](c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL1081285 pA2 1.995 nM
CN/C(=N\S(=O)(=O)N1CCCCC1)N1CCC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL575680 pA2 1.995 nM
C[C@H]1CN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)CCN1C CHEMBL1209710 pKi 1.995 nM
CCc1sc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)nc1CN(CC)CCO CHEMBL1762814 pEC50 1.995 nM
COc1ccc(Cl)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760649 pIC50 1.995 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL561013 pKi 1.995 nM
CCCCCCC(C)(C)c1ccc2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL331838 Ki 2.0 nM
CCCn1cnc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c1=O CHEMBL203925 Ki 2.0 nM
C[C@H](NC(=O)C(C)(C)Oc1ccccc1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL217862 IC50 2.0 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(OCF)cc1)c1cc(F)cc(C#N)c1 CHEMBL226685 IC50 2.0 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL245742 Ki 2.0 nM
COc1ccc(C2(c3ccc(Cl)cc3Cl)Oc3cc(F)c(C(=O)N4CCCCC4)cc3O2)cc1 CHEMBL263391 Ki 2.0 nM
O=C(c1cc2c(cc1F)OC(c1ccccc1F)(c1ccc(Cl)cc1Cl)O2)N1CCOCC1 CHEMBL408427 EC50 2.0 nM
O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1F)(c1ccc(F)cc1F)O2)N1CCC(F)(F)CC1 CHEMBL259654 EC50 2.0 nM
COc1ccc(-c2c(C#N)c(C(=O)NN3CCCC3)nn2-c2ccc(Cl)cc2Cl)cc1 CHEMBL476404 Ki 2.0 nM
O=C(Cc1ccccc1)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL490023 EC50 2.0 nM
CN(C)C(=O)Oc1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)[C@@H]3C[C@H]3c3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL485860 IC50 2.0 nM
Cc1nc(C(=O)N[C@@H]2CC(C)(C)Oc3nc(-c4ccc(Cl)cc4Cl)c(-c4ccc(Cl)cc4)cc32)n[nH]1 CHEMBL1098876 IC50 2.0 nM
CC(C)[C@H](N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O CHEMBL2153669 IC50 2.0 nM
CC(C)(C)[C@H](N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O CHEMBL2153672 IC50 2.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCC/C2=C\c1ccc(Cl)s1)c1ccccn1 CHEMBL3964744 EC50 2.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(C5CCCCC5)CC4)ncnc32)cc1 CHEMBL4225049 Ki 2.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(c5ccccc5)CC4)ncnc32)cc1 CHEMBL4228096 Ki 2.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(c5ccccn5)CC4)ncnc32)cc1 CHEMBL4229172 Ki 2.0 nM
N#Cc1ccccc1N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4225213 Ki 2.0 nM
COc1ccccc1N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4226066 Ki 2.0 nM
Fc1ccc(N2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cc1 CHEMBL4224946 Ki 2.0 nM
N#Cc1ccc(N2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cc1 CHEMBL4228748 Ki 2.0 nM
FC(F)(F)Oc1ccccc1CN1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4227442 Ki 2.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(CCc5ccccc5)CC4)ncnc32)cc1 CHEMBL4226777 Ki 2.0 nM
O=C(C1CCSCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4249233 Ke 2.0 nM
O=C(Nc1ccccc1F)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4249329 Ke 2.0 nM
O=C(Nc1ccc(F)cc1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4248870 Ke 2.0 nM
CC1(NC(=O)NC2CCC(F)(F)CC2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4452900 Ke 2.0 nM
Cc1ccc(Cn2nc(C(=O)N[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL381791 Ki 2.0 nM
CC(C(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL4446721 Ke(app) 2.0 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccc(F)cc1F CHEMBL4476077 Ke(app) 2.0 nM
COc1ccc(-c2ccc(CNS(=O)(=O)c3cc4ccccc4[nH]3)cc2)cc1 CHEMBL4580709 IC50 2.0 nM
O=S(=O)(NCc1ccc(-c2ccccc2)cc1)c1cc2ccccc2[nH]1 CHEMBL4474264 IC50 2.0 nM
O=C(CC1CCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2436762 Ki 2.02 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2ccc(-c3ccccc3)cc21 CHEMBL2087110 Ki 2.03 nM
CCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(N=C=S)cc12 CHEMBL3758877 EC50 2.09 nM
CCCCC#Cc1ccc(-c2c(C)c(C(=O)NC3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL494300 IC50 2.1 nM
N#CCc1c(C(=O)N2CCc3ccc(C(F)(F)F)cc3C2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589649 IC50 2.1 nM
N#CCc1c(C(=O)NCc2ccc(F)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL594655 IC50 2.1 nM
CCc1cc(C(=O)N[C@@H]2CC(C)(C)Oc3nc(-c4ccc(Cl)cc4Cl)c(-c4ccc(Cl)cc4)cc32)n[nH]1 CHEMBL1095789 IC50 2.1 nM
CC1(C)CC(NC(=O)C(C)(C)CO)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1083016 IC50 2.1 nM
Cc1c(C(=O)N2CCC(NC(=O)NCc3ccccc3)(c3ccccc3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2030744 Ke 2.1 nM
CC(C)(NC(=O)c1nn(CC2CCOCC2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354938 EC50 2.1 nM
CC(C)[C@H](NC(=O)c1nn(CCCCCF)c2ccccc12)C(N)=O CHEMBL4077214 EC50 2.1 nM
CCCCCn1nc(C(=O)N[C@H](C(N)=O)C(C)C)c2ccccc21 CHEMBL4101222 EC50 2.1 nM
CC(C)[C@H](NC(=O)c1nn(Cc2ccc(F)cc2)c2ccccc12)C(N)=O CHEMBL4083220 EC50 2.1 nM
CC(C)[C@H](NC(=O)c1nn(CC2CCCCC2)c2ccccc12)C(N)=O CHEMBL4097041 EC50 2.1 nM
CCCCCCc1c(C(=O)NCCc2ccc(N=[N+]=[N-])cc2)[nH]c2ccc(Cl)cc12 CHEMBL4776235 EC50 2.1 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC(C)CO CHEMBL55802 Log Ki 2.14 nM
C=C(CCCCCC)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL239840 Ki 2.17 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(=O)C[C@@H]21 CHEMBL947 Ki 2.19 nM
Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1ccc(Cl)cc1)CCN(N1CCCCC1)C2=O CHEMBL230356 Ki 2.2 nM
O=C(NC1CCCCC1)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 CHEMBL389175 Ki 2.2 nM
O=C(N[C@H]1c2ccccc2C[C@H]1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 CHEMBL229967 Kb 2.2 nM
O=C(Cc1ccccc1C(F)(F)F)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL514697 EC50 2.2 nM
CCN(CC)c1nc(C(C)(C)C)nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL466686 IC50 2.2 nM
N#CCc1c(C(=O)N[C@@H]2C[C@H]3CC[C@@H]2C3)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589885 IC50 2.2 nM
COC(=O)c1ccccc1C1CCN(C(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC#N)CC1 CHEMBL606249 IC50 2.2 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2c(Cl)cccc2Cl)CC1 CHEMBL1087250 Ki 2.2 nM
O=[N+]([O-])CC(c1ccccc1F)c1c(-c2cccc(F)c2)[nH]c2cc(F)ccc12 CHEMBL4467516 EC50 2.2 nM
C[C@@H]1CC(O)(c2cccc(F)c2)C[C@H](C)N1C(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC(N)=O CHEMBL5399041 IC50 2.2 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C=O)C[C@@H]21 CHEMBL59540 Ki 2.24 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL5178491 Ki 2.28 nM
CC(=O)Nc1c(C(C)=O)c(=O)n(CC(C)C)c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL201388 IC50 2.3 nM
CC(=O)Nc1c(C(C)=O)c(=O)n(Cc2ccccc2)c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL202169 IC50 2.3 nM
O=S(=O)(NC[C@@H]1CC[C@@H](c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1)c1cccc2ccccc12 CHEMBL591541 Ki 2.3 nM
O=C(NC1CCCCC1)N1CCN(C(c2cccc(Cl)c2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1093378 Ki 2.3 nM
Cc1c(C(=O)NCCCCCCCCCCCNCCCCCCCCCCCN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269774 Ki 2.3 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1cc2c(c1)CCCC2 CHEMBL1909848 Ki 2.3 nM
CCCCCn1cc(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc21 CHEMBL2206859 Ki 2.3 nM
CCOC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2436754 Ke 2.3 nM
CC(C)(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 CHEMBL3959623 Ki 2.33 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL5189892 Ki 2.33 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccc(F)cc21 CHEMBL4435655 Ki 2.35 nM
COCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=S)NC1CCC(F)(F)CC1 CHEMBL605526 IC50 2.4 nM
COc1cc(C(=O)NC2(C(=O)N[C@H](C)c3ccc(-n4nc(C#N)c5ccccc54)cc3F)CC2)on1 CHEMBL1801079 Ki 2.4 nM
Cc1c(C(=O)N2CCC(NC(=O)NC(C)(C)C)(c3ccccc3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2030743 Ke 2.4 nM
COc1ccc(NC(=O)c2ccc(Cn3ccnn3)c3ccccc23)c(C(=O)NCC2CCOCC2)n1 CHEMBL2316378 IC50 2.4 nM
O=C(NCc1ccccc1F)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4534007 Ki 2.4 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCC(Nc5ccccn5)CC4)ncnc32)cc1 CHEMBL4437469 Ki 2.4 nM
CS/C(N)=N/C(=N/S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5080268 Ki 2.4 nM
COc1ccc(/C=C2\C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 CHEMBL123515 Ki 2.43 nM
CCCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152813 Ki 2.45 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL74415 Log Ki 2.49 nM
CC(NC(=O)C(C)(C)Oc1ccc(Cl)cc1)C(Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL219188 IC50 2.5 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(C(F)(F)F)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL245784 Ki 2.5 nM
COCCOc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(=O)(=O)C(F)(F)F)cc2)c(S(=O)(=O)c2ccccc2F)c1 CHEMBL396169 Ki 2.5 nM
O=C(C1CCCCC1)N1CCN(S(=O)(=O)c2cccc3ccccc23)CC1C(F)(F)F CHEMBL489852 EC50 2.5 nM
CC(C)N1CCc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL485013 Ki 2.5 nM
CC(C)CN1CCc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL482985 Ki 2.5 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccc(F)cc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1084695 Ki 2.5 nM
CCCCCn1cc(C(=O)c2ccc(I)c3ccccc23)c2ccccc21 CHEMBL2206838 Ki 2.5 nM
CCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(CO)=C[C@@H]21 CHEMBL4747195 Ki 2.5 nM
N/C(=N\C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(Cl)cc1 CHEMBL5083073 IC50 2.5 nM
Cc1cc(Br)ccc1CNC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 CHEMBL598769 IC50 2.51 nM
C/N=C(\NS(=O)(=O)c1ccc(C)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL349771 pA2 2.512 nM
C/N=C(\NS(=O)(=O)c1cccc(Cl)c1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL158537 pA2 2.512 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(C(F)(F)F)cc1 CHEMBL174163 pA2 2.512 nM
Cc1c(C(=O)OC(C)(C)C)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL178428 pA2 2.512 nM
N#Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL369072 pA2 2.512 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL368749 pA2 2.512 nM
CCN(CC)S(=O)(=O)N/C(=N\C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL195050 pA2 2.512 nM
CC(C)CNC(=O)c1ccc2c(c1)N=C(c1cccc(Cl)c1)c1ccccc1S2 CHEMBL520455 pIC50 2.512 nM
O=C(NN1CCCCC1)c1ccc2c(c1)N=C(C1CCCCC1)c1ccccc1S2 CHEMBL483749 pKi 2.512 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL558598 pA2 2.512 nM
O=S1(=O)CCN(/C(=N\S(=O)(=O)c2ccc(Cl)cc2)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)CC1 CHEMBL585736 pA2 2.512 nM
CN/C(=N\S(=O)(=O)c1ccc(C(F)(F)F)cc1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1 CHEMBL1081306 pA2 2.512 nM
CCSc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL1088349 pA2 2.512 nM
CSc1c(C(=O)NN2CCCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1088376 pA2 2.512 nM
COc1cccc2c(C(=O)N3CCN4CCCC[C@H]4C3)cn(CC3CCCCC3)c12 CHEMBL1287846 pKi 2.512 nM
CCc1sc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)nc1CN(CCO)C(C)C CHEMBL1762815 pEC50 2.512 nM
Cc1c(C(=O)N[C@@H]2CCCC[C@@H]2N(C)C)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 CHEMBL4072418 pKi 2.512 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(C)c3)cc1OC2(C)C CHEMBL471295 Ki 2.53 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)Oc1ccccc1 CHEMBL2436755 Ki 2.55 nM
CCCc1ccc(C(=O)c2cn(CCCCCF)c3cccc(F)c23)c2ccccc12 CHEMBL4444832 Ki 2.55 nM
COc1ccc(Cl)cc1Cn1c(C(=O)NCC2(CO)CCC2)cc2cc(C#N)ccc21 CHEMBL1760659 pIC50 2.57 nM
CCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL306764 Log Ki 2.58 nM
CCCCC#Cc1ccc(-c2c(C)c(C(=O)NCCCCCC)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL494299 IC50 2.6 nM
N#CCc1c(C(=O)NCc2cccc(Cl)c2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL602705 IC50 2.6 nM
COc1ccc(C(c2ccc(Cl)cc2Cl)N2CCN(C(=O)NC3CCCCC3)CC2)cc1 CHEMBL1091813 Ki 2.6 nM
O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(F)cc2)CC1)c1ccccc1F CHEMBL4452479 Ki 2.6 nM
O=C(O)Cc1c(C(=O)N2CCC(c3cccc(F)c3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5421042 IC50 2.6 nM
N#Cc1ccc2c(c1)cc(C(=O)NCCC1(O)CCC1)n2Cc1cccc(OC(F)(F)F)c1 CHEMBL1760669 pIC50 2.63 nM
CC(C)CCC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2436761 Ki 2.67 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)cc1F CHEMBL362219 IC50 2.7 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(O)c1 CHEMBL56799 Ki 2.7 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(C(=O)OC)c1 CHEMBL233180 Ki 2.7 nM
CCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL252742 Ki 2.7 nM
CC(C)(C)Nc1nc(C(C)(C)C)nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL513648 IC50 2.7 nM
CCc1c(C(=O)NCCc2ccc(C(=O)c3ccccc3)cc2)[nH]c2ccc(Cl)cc12 CHEMBL4744733 EC50 2.7 nM
C1=C(CCN2CCOCC2)c2ccccc2/C1=C/c1cccc2ccccc12 CHEMBL127644 Ki 2.72 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(C#N)c3)cc1OC2(C)C CHEMBL471366 Ki 2.72 nM
C[C@H](CO)NC(=O)CCC/C=C\C/C=C\CCOc1cccc(C(C)(C)CCCCN=[N+]=[N-])c1 CHEMBL240315 Ki 2.74 nM
N/C(=N\C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(F)cc1 CHEMBL5088686 IC50 2.77 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL5192756 Ki 2.79 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(Cl)cc1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(F)c1 CHEMBL2113250 IC50 2.8 nM
Cc1c2c(n(-c3ccccc3Cl)c1-c1ccc(Cl)cc1)CCN(C1CCCCC1)C2=O CHEMBL230992 Ki 2.8 nM
C[C@H](NS(=O)(=O)c1cccc(-c2ccccc2)c1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL230717 IC50 2.8 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(Cl)c3)cc1OC2(C)C CHEMBL521366 Ki 2.8 nM
CC(C)(C(=O)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1)c1ccccc1 CHEMBL522602 EC50 2.8 nM
CCCCCn1cc(C(=O)N[C@H]2C(C)(C)[C@H]3CC[C@]2(C)C3)c(=O)c2cc(Br)ccc21 CHEMBL1215991 Ki 2.8 nM
CCN(CCCC(=O)NC1CC1)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1 CHEMBL2029719 Ki 2.8 nM
CC(C)(NC(=O)c1cn(CCCCCF)c2ccccc12)c1ccccc1 CHEMBL5220222 EC50 2.8 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(OCC)cc3)c(-c3ccc(OCC)cc3)n2)CC1 CHEMBL495892 Ki 2.84 nM
CC1=C(CCN2CCOCC2)c2ccccc2/C1=C/c1cccc2ccccc12 CHEMBL123916 Ki 2.84 nM
COC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCC1CCCCC1 CHEMBL360783 IC50 2.9 nM
CCCCCCC1(c2ccc(-c3cc(C)cc(C)c3)c(O)c2)CCCC1 CHEMBL233634 Ki 2.9 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccn2)cc1 CHEMBL245777 Ki 2.9 nM
COCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)NC1CCC(F)(F)CC1 CHEMBL595690 IC50 2.9 nM
CN(CCO)C(=O)C(C)(C)NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2018657 Ki 2.9 nM
Cc1c(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2030754 Ki 2.9 nM
CS(=O)(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2180218 Ke 2.9 nM
CCn1nc2c(-c3ccc(C)cc3)c(-c3ccc(C#N)cc3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260750 Ki 2.9 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cc(-c4ccco4)cnc3n(Cc3cccc(F)c3)c2=O)CC1 CHEMBL5173419 Ki 2.9 nM
O=C(O)Cc1c(C(=O)N2CCC(c3ccccc3F)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5435192 IC50 2.9 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2ncn1CCF CHEMBL202583 Ki 3.0 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(Cl)cc1)[C@@H](Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL218649 IC50 3.0 nM
O=S(=O)(c1cc2c(cc1F)OC(c1ccc(F)cc1F)(c1ccc(F)cc1F)O2)N1CCC(F)(F)CC1 CHEMBL409471 Ki 3.0 nM
O=S(=O)(c1cc2c(cc1F)OC(c1ccc(F)cc1)(c1ccc(Cl)cc1Cl)O2)N1CCOCC1 CHEMBL262857 EC50 3.0 nM
CCCCC#Cc1ccc(-c2c(C)c(C(=O)NCCCC)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL462069 IC50 3.0 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-c3cn[nH]n3)cc(C(F)(F)F)c2)CC1 CHEMBL528997 IC50 3.0 nM
COc1ccc(-c2cc3c(nc2-c2ccccc2Cl)nc(C(C)(C)C)n2c(=O)[nH]nc32)cc1 CHEMBL467701 IC50 3.0 nM
N#CCc1c(C(=O)N2CCC(O)(c3ccc(F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL596377 IC50 3.0 nM
Cc1ccc(C(c2ccc(Cl)cc2Cl)N2CCN(C(=O)NN3CCCCC3)CC2)cc1 CHEMBL1091812 Ki 3.0 nM
C[C@H](O)C(=O)NC1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1094521 IC50 3.0 nM
C[C@@H](O)C(=O)NC1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1083646 IC50 3.0 nM
CC(C)(O)CC(=O)Nc1ccc2ccn(Cc3cccc(-c4cccc5c4OCO5)n3)c2c1 CHEMBL1224536 IC50 3.0 nM
CCc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1cccc1 CHEMBL1909850 Ki 3.0 nM
CCOc1ccc(Cc2nc3cc(N(C)S(=O)(=O)c4cccs4)ccc3n2CC2CCCCC2)nc1 CHEMBL1950329 Ki 3.0 nM
CCOC(=O)N1CCC(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)CC1 CHEMBL2030765 Ke 3.0 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccc(C#N)c(C)c3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260746 Ki 3.0 nM
CCc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#Cc2ccc(C(F)(F)F)cc2)s1 CHEMBL3341897 Ki 3.0 nM
O=c1cc(NC2CCN(CC(F)(F)F)CC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3986695 EC50 3.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(Cc5ccncc5Cl)CC4)ncnc32)cc1 CHEMBL4229032 Ke 3.0 nM
COc1ccc(N2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cc1 CHEMBL4225525 Ki 3.0 nM
N#Cc1ccccc1CN1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4226710 Ki 3.0 nM
CS(=O)(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4241237 Ke 3.0 nM
O=C(Nc1ccccc1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4245522 Ke 3.0 nM
CCS(=O)(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4245455 Ki 3.0 nM
O=S(=O)(CC1CCOCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4245443 Ki 3.0 nM
O=C(OC1CCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4237943 Ki 3.0 nM
O=C(OCC1CCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4237503 Ki 3.0 nM
O=C(NC1CCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4449377 Ki 3.0 nM
O=C(NCc1ccc(F)cc1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4555599 Ki 3.0 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)OCc1ccccc1 CHEMBL4555424 Ke(app) 3.0 nM
CCCCC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(C(F)(F)F)nc2)CC1 CHEMBL4475996 Ki 3.0 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)C1CCSCC1 CHEMBL4445108 Ki 3.0 nM
Cc1ccc(-c2ccc(CNS(=O)(=O)c3cc4ccccc4[nH]3)cc2)cc1 CHEMBL4554003 IC50 3.0 nM
CN(C)c1ccc(-c2ccc(CNS(=O)(=O)c3cc4ccccc4[nH]3)cc2)cc1 CHEMBL4436256 IC50 3.0 nM
COc1ccc2[nH]c(S(=O)(=O)NCc3ccc(-c4ccc(F)nc4)cc3)cc2c1 CHEMBL4457926 IC50 3.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)cc2F)cn1)c1cc2cc(Cl)ccc2[nH]1 CHEMBL4438146 IC50 3.0 nM
Cc1ccccc1C(C[N+](=O)[O-])c1c(-c2ccccc2)[nH]c2ccccc12 CHEMBL4787492 EC50 3.0 nM
C/C(N)=N\C(=N\S(=O)(=O)N1CCCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5087110 Ki 3.0 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N1CCOCC1 CHEMBL73987 Log Ki 3.06 nM
CNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL181875 IC50 3.1 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)cc1 CHEMBL425527 IC50 3.1 nM
CN(C)CCCN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL567228 Ki 3.1 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2F)CC1 CHEMBL1088161 Ki 3.1 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(C)cc3)cc1OC2(C)C CHEMBL512511 Ki 3.13 nM
C/N=C(\NS(=O)(=O)c1ccc(F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL347454 pA2 3.162 nM
C/N=C(\NS(=O)(=O)c1ccc2ccccc2c1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL351123 pA2 3.162 nM
CN(C)/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL160214 pA2 3.162 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)c1Cl CHEMBL436471 pA2 3.162 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1 CHEMBL175292 pA2 3.162 nM
CC/N=C(\NS(=O)(=O)N(CC)CC)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL372697 pA2 3.162 nM
CSc1c(C(=O)NN2CCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL1088506 pA2 3.162 nM
CS(=O)(=O)c1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL1088222 pA2 3.162 nM
CCCCC/C=C/Cc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL159361 Kd 3.19 nM
C[C@H](NS(=O)(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL230715 IC50 3.2 nM
CC(C)(C)c1nc2nc(-c3ccccc3C#N)c(-c3ccc(Cl)cc3)cc2c2n[nH]c(=O)n12 CHEMBL467529 IC50 3.2 nM
C[C@H](NC(=O)C(C)(C)Nc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL582806 EC50 3.2 nM
CC(C)C1CC(=O)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2O1 CHEMBL1086012 IC50 3.2 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)C(F)(F)F CHEMBL2180212 Ke 3.2 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccncc3F)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260754 Ki 3.2 nM
CC(C)(C)/C(N)=N/C(=N/S(=O)(=O)N1CCC(F)(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5078566 IC50 3.2 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCOC CHEMBL75591 Log Ki 3.26 nM
CCCCCC1=NN(C(=O)NC(C)(C)c2ccccc2)CC1c1ccccc1 CHEMBL1224691 Ki 3.26 nM
O=C(c1cc2c(cc1F)O[C@](c1ccc(F)cc1)(c1ccc(Cl)cc1Cl)O2)N1CCOCC1 CHEMBL258539 Ki 3.3 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)C1CCCCC1 CHEMBL2436756 Ke 3.3 nM
N/C(=N\C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(F)cc1 CHEMBL5092394 Ki 3.3 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cc(-c4ccco4)cnc3n(CCCCF)c2=O)CC1 CHEMBL5199801 Ki 3.3 nM
C[C@@H](NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1Cc1nn[nH]n1)c1ccc(C(F)(F)F)cc1 CHEMBL5396920 IC50 3.3 nM
CCCC/C=C/CCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL423422 Kd 3.36 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(C(F)(F)F)cc1 CHEMBL361519 IC50 3.4 nM
CNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCC1CCCCC1 CHEMBL360723 IC50 3.4 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(Cl)cc1)[C@@H](Cc1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL2113253 IC50 3.4 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(Cl)c2ccccc12 CHEMBL482356 Ki 3.4 nM
Cc1c(C(=O)N[C@@H](C)C2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL573546 Ki 3.4 nM
N#CCc1c(C(=O)N2CCC(O)(Cc3ccccc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL592051 IC50 3.4 nM
O=S(=O)(NCCC1CCC(c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1)C1CC1 CHEMBL589985 Ki 3.4 nM
COc1ccc(-c2c(C#N)c(C(=O)NN3CCCCC3)nn2-c2ccccc2[125I])cc1 CHEMBL1079079 Ki 3.4 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCCOCCO CHEMBL2018660 Ki 3.4 nM
CCCCCCC(C)(C)c1ccc(C2CC(O)CCC2CCCO)c(O)c1 CHEMBL77520 Ki 3.4 nM
C/C(N)=N\C(=N\S(=O)(=O)N1CCC(F)(F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5087041 Ki 3.4 nM
COC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccccc1 CHEMBL359865 IC50 3.5 nM
CCc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Br)cc1 CHEMBL189676 Ki 3.5 nM
Cc1c2c(n(-c3ccccc3Cl)c1-c1ccc(Cl)cc1)CCN(N1CCCCC1)C2=O CHEMBL231201 Ki 3.5 nM
CC(C)NC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1ccc(F)c(F)c1 CHEMBL247307 IC50 3.5 nM
C[C@H](NC(=O)C(C)(C)Nc1cc(C(C)(C)C)on1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL582820 EC50 3.5 nM
Nc1c(C(=O)c2ccccc2)oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL1089018 IC50 3.5 nM
Cc1c(C(=O)N2CCC(NS(C)(=O)=O)(c3ccccc3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2029362 Ke 3.5 nM
CCCCCc1cc(OC)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL4644215 Ki 3.5 nM
CC1=CCC2C(C1)c1c(O)cc(C/C=C/CCCC[N+](=O)[O-])cc1OC2(C)C CHEMBL439647 Kd 3.56 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCC(C(=O)NCCO)C(C)C CHEMBL77801 Log Ki 3.6 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccn2)cc1 CHEMBL246351 Ki 3.6 nM
Cc1c(C(=O)NC2CCN(C(=O)C3CCCC3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL3759255 Ke 3.6 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2cccc(F)c21 CHEMBL4516360 Ki 3.62 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O CHEMBL190461 Log Ki 3.64 nM
CCCCCCC#CCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL159309 Kd 3.7 nM
COCCn1c(=O)c(C(C)=O)c(NC(C)=O)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc21 CHEMBL371252 IC50 3.7 nM
CCc1c(C(=O)N[C@H]2CCCC[C@@H]2O)nc(-c2ccccc2Cl)n1-c1ccc(Br)cc1 CHEMBL231118 Ki 3.7 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1ccc(F)c(F)c1 CHEMBL246723 IC50 3.7 nM
C[C@H](NC(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL396368 Ki 3.7 nM
CN1c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2C(C(=O)NCO)CC1(C)C CHEMBL1082330 IC50 3.7 nM
Cc1cccc(-c2c(O)cc(C(C)(C)c3cccs3)cc2O)c1 CHEMBL3923170 Ki 3.7 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)nc1N1CCN(S(=O)(=O)c2cc(F)cc(F)c2)CC1 CHEMBL394055 IC50 3.8 nM
Cc1c(-c2cn(-c3ccccc3)cn2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL568221 Ki 3.8 nM
N#CCc1c(C(=O)N2CCN(c3ncccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL590382 IC50 3.8 nM
N#CCc1c(C(=O)N2CCC(c3ncccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL594982 IC50 3.8 nM
O=S(=O)(NCC[C@@H]1CC[C@@H](c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1)C1CC1 CHEMBL591352 Ki 3.8 nM
O=C(NC1CCCCC1)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1 CHEMBL276312 Ki 3.9 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1cc(Cl)cc(Cl)c1 CHEMBL392626 IC50 3.9 nM
CCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL398905 Ki 3.9 nM
CC(C)(C)OC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2180216 Ke 3.9 nM
O=C(N[C@@H]1CCCC[C@H]1O)c1cnc(OCC2CC2)c(-c2ccc(Cl)cc2)c1 CHEMBL3109771 EC50 3.9 nM
C/C(N)=N/C(=N/S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5073465 Ki 3.9 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2cccnc2n(CCOCCF)c1=O CHEMBL5183565 Ki 3.9 nM
CCCCCn1cc(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2cccnc21 CHEMBL4476642 Ki 3.94 nM
[3H]c1cc(-c2cnn3c(=O)n(Cc4ccc(C(F)(F)F)nc4[3H])nc3c2-c2ccncc2)ccc1Cl CHEMBL1911375 Kd 3.95 nM
Cc1ccc(S(=O)(=O)NC(=N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)cc1 CHEMBL158935 pA2 3.981 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cn1 CHEMBL368660 pA2 3.981 nM
Cc1c(C(=O)N2CCc3ccccc3C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL175291 pA2 3.981 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)c1Br CHEMBL427497 pA2 3.981 nM
C/N=C(\NS(=O)(=O)N1CCCCCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL197099 pA2 3.981 nM
CN/C(=N\S(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1 CHEMBL1081286 pA2 3.981 nM
CN/C(=N\S(=O)(=O)N1CCC(F)CC1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1 CHEMBL1081832 pA2 3.981 nM
C[S+]([O-])c1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1098696 pA2 3.981 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)c1CO CHEMBL1087721 pA2 3.981 nM
CCN1[C@H](C)CN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)C[C@@H]1C CHEMBL1209644 pEC50 3.981 nM
CCCCC1=NN(C(=O)NC(C)(C)c2ccccc2)CC1c1ccccc1 CHEMBL1223589 pEC50 3.981 nM
CCCCCN1N=C(C(=O)NC(C)(C)c2ccc(F)cc2)CC1c1ccccc1 CHEMBL1223777 pEC50 3.981 nM
CCCCCN1N=C(C(=O)N[C@H]2C[C@H]3CC[C@]2(C)C3(C)C)CC1c1ccccc1F CHEMBL1223835 pEC50 3.981 nM
CN(CC(N)=O)Cc1nc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)no1 CHEMBL1682272 pKi 3.981 nM
CCc1cccc2c(-c3nsc(CN4CCCC4)n3)cn(CC3CCCCC3)c12 CHEMBL1762797 pEC50 3.981 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CCC(=O)CC21 CHEMBL2218896 pKi 3.981 nM
O=C(NCCO)C1CCN(Cc2nc(-c3cn(CC4CCOCC4)c4c(Cl)cccc34)no2)CC1 CHEMBL1682275 pKi 3.981 nM
Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL179473 IC50 4.0 nM
CCn1cnc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c1=O CHEMBL202419 Ki 4.0 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2cnn1CC(F)(F)F CHEMBL381858 Ki 4.0 nM
O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2ncn1Cc1ccccc1 CHEMBL379667 Ki 4.0 nM
O=C(NN1CCCCC1)c1cnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1 CHEMBL390146 IC50 4.0 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1cccc(Cl)c1 CHEMBL246721 IC50 4.0 nM
O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1)(c1ccc(Cl)cc1Cl)O2)N1CCOCC1 CHEMBL259656 Ki 4.0 nM
O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1)(c1ccc(Cl)cc1Cl)O2)N1CCCCC1 CHEMBL258753 Ki 4.0 nM
O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1F)(c1ccc(F)cc1F)O2)N1CCOCC1 CHEMBL409217 EC50 4.0 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(CCO)cc(C(F)(F)F)c2)CC1 CHEMBL490026 IC50 4.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccccc23)C1(C)C CHEMBL271158 EC50 4.0 nM
CC1(C)C[C@@H](NC(=O)c2ccccc2O)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1094839 IC50 4.0 nM
CCCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152803 Ki 4.0 nM
COc1cccc(S(=O)(=O)/N=C(\N[C@H](C(N)=O)C(C)C)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)c1 CHEMBL2153763 IC50 4.0 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(OC(=O)CCCN3CCOCC3)cc(C(C)(C)CCCCC#N)cc1OC2(C)C CHEMBL3233403 Ki 4.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCC/C2=C\c1ccc(F)cc1)c1ccccn1 CHEMBL3958380 EC50 4.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCC/C2=C\c1ccc(Cl)cn1)c1ccccn1 CHEMBL3914883 EC50 4.0 nM
COc1ccc(/C=C2\CN(C(=O)Cn3ccnn3)Cc3c(C(=O)N[C@H](C)c4ccccc4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 CHEMBL3950659 EC50 4.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(Cc5ccccc5)CC4)ncnc32)cc1 CHEMBL4225260 Ki 4.0 nM
Cc1ccccc1CN1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4227013 Ki 4.0 nM
CC(C)(C)OC(=O)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4249237 Ke 4.0 nM
O=C(Nc1ccc(OC(F)F)nc1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4242565 Ki 4.0 nM
O=C(Nc1ccc(F)cc1F)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4473591 Ke 4.0 nM
O=C(Nc1ccccc1F)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4519913 Ki 4.0 nM
O=S(=O)(CCC(F)(F)F)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4544209 Ki 4.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)cc2F)cc1)c1cc2cc(Cl)ccc2[nH]1 CHEMBL4462538 IC50 4.0 nM
O=S(=O)(NCc1ccc(-c2ccccc2)cc1)c1cc2ccc(Cl)cc2[nH]1 CHEMBL4571226 IC50 4.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)nc2F)cc1)c1cc2cc(Cl)ccc2[nH]1 CHEMBL4449492 IC50 4.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)cc2F)cn1)c1cc2cc(Br)ccc2[nH]1 CHEMBL4550424 IC50 4.0 nM
CCCCCn1nc(C(=O)NC23CC4CC(CC(O)(C4)C2)C3)cc1C(C)(C)C CHEMBL4778743 EC50 4.0 nM
N/C(=N/C(=N/S(=O)(=O)N1CCCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(F)cc1 CHEMBL5084492 IC50 4.0 nM
CC(C)CC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2436759 Ki 4.01 nM
CC(C)(C)NC(=O)C1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL3922339 Ki 4.08 nM
CCn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL179507 IC50 4.1 nM
Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1ccc(C(F)(F)F)cc1)CCN(C1CCCCC1)C2=O CHEMBL230571 Ki 4.1 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2c(N)cccc2F)cc1 CHEMBL245350 Ki 4.1 nM
CC(C)Nc1nc(C(C)(C)C)nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL511774 IC50 4.1 nM
N#CCc1c(C(=O)NCc2ccccc2F)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL589652 IC50 4.1 nM
Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3nccc(/C=C/c4ccccc4)c3c2)cc1 CHEMBL3972458 EC50 4.1 nM
N#CCc1c(C(=O)NCc2ccc(C#N)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL602106 IC50 4.2 nM
N#Cc1ccc(S(=O)(=O)NCC[C@@H]2CC[C@@H](c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)cc1 CHEMBL591994 Ki 4.2 nM
N#Cc1ccc(Cn2nc3c(-c4ccncc4)c(-c4ccc(Cl)cc4)c(=O)n(Cc4ccc(C#N)cc4)n3c2=O)cc1 CHEMBL3260737 Ki 4.2 nM
Cc1c(C(=O)NCCCCCCCN(C)CCCCCCCNC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269770 pA2 4.266 nM
CC(C)(C)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1N CHEMBL1089352 IC50 4.3 nM
CC(C)(O)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CO CHEMBL1092169 IC50 4.3 nM
CC(C)(O)C(=O)c1oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CO CHEMBL1084038 IC50 4.3 nM
CC(C)C(=O)N(C)C1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063251 Ki 4.3 nM
O=C(NCC1CCC1)c1nccnc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12 CHEMBL2316380 IC50 4.3 nM
Cc1c(C(=O)NC2CCN(S(=O)(=O)CCC(F)(F)F)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL3759254 Ke 4.3 nM
CCCCCn1nc(C(=O)N[C@@H](C(=O)OC)C(C)(C)C)cc1C(C)(C)C CHEMBL4786220 EC50 4.3 nM
Cc1ccc(C(F)(F)F)cc1Cn1c(C(=O)NCCC(C)(C)O)cc2cc(C#N)ccc21 CHEMBL1760664 pKi 4.365 nM
O=C(c1cccc2ccccc12)c1cn(CCCCCF)c2cccc(F)c12 CHEMBL4474739 Ki 4.38 nM
O=C(NC1CCCCC1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1 CHEMBL389198 Kb 4.4 nM
CC(C)(NC(=O)c1nn(CCC2CCOCC2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354939 EC50 4.4 nM
O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1cccc2[nH]cnc12 CHEMBL3798331 EC50 4.4 nM
O=c1cc(NC2CCN(S(=O)(=O)C(F)(F)F)CC2)c2cc(C(c3ccc(Cl)cc3)c3nccs3)ccc2[nH]1 CHEMBL3921520 EC50 4.4 nM
Cc1c(C(=O)NCCCCCCCNCCCCCCCNC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269766 Ki 4.41 nM
FC1(F)CCC(NC(=S)c2cnc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)n2)CC1 CHEMBL593606 IC50 4.5 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccncc3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260743 Ki 4.5 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1cnn(CC)c1-2 CHEMBL4441538 Ki 4.5 nM
Cc1c(C(=O)NCCCCCCCCCN(C)CCCCCCCCCN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269775 pA2 4.571 nM
Cc1ccc(-n2cc(C(=O)NC3CCCCC3)nc2-c2ccccc2Cl)cc1 CHEMBL229749 Ki 4.6 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)ccc2C)c(O)c1 CHEMBL232411 Ki 4.6 nM
O=C(Cc1cccc(C(F)(F)F)c1)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL477267 EC50 4.6 nM
O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)cnn12 CHEMBL1911374 Kd 4.6 nM
Cc1c(C(=O)Nc2ccc(O)cc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2022405 Ki 4.6 nM
O=S(=O)(N1CCC(Nc2ncnc3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)CC1)C(F)(F)F CHEMBL4747411 EC50 4.6 nM
C#CCCCC#CCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL159862 Kd 4.7 nM
COc1ccc(-c2c(C#N)c(C(=O)NN3CCCCC3)nn2-c2ccccc2Br)cc1 CHEMBL514361 Ki 4.7 nM
CCN1CCc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL484163 Ki 4.7 nM
CC(C)(C)N1CCc2c(nn(-c3ccccc3Cl)c2-c2ccc(Cl)cc2)C1=O CHEMBL518982 Ki 4.7 nM
Cc1c(-c2cn(C3CCCCC3)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL585095 Ki 4.7 nM
CCCCCN1N=C(C(=O)N[C@H]2C[C@H]3CC[C@]2(C)C3(C)C)CC1c1ccccc1 CHEMBL1223778 Ki 4.7 nM
CC(=O)NCCNC(=O)C(C)(C)NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2018662 Ki 4.7 nM
CCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152812 Ki 4.7 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3cnc(C)nc3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260753 Ki 4.7 nM
CC(C)(NC(=O)c1cn(CCCCCF)c2ncccc12)c1ccccc1 CHEMBL5218844 EC50 4.7 nM
CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(CCCCF)c2=O)CC1 CHEMBL5195027 Ki 4.8 nM
C[C@@H](NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1Cc1nn[nH]n1)c1ccc(OC(F)(F)F)cc1 CHEMBL5419437 IC50 4.8 nM
Cc1ccc(F)cc1Cn1c(C(=O)NCC2(CO)CCC2)cc2cc(C#N)ccc21 CHEMBL1760660 pIC50 4.898 nM
CCCCCC#CCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL161247 Kd 4.9 nM
COc1ccc(-n2cc(C(=O)NC3CCCCC3)nc2-c2ccc(Cl)cc2Cl)cc1 CHEMBL229583 Ki 4.9 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(NC3CC3)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL246552 Ki 4.9 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(F)c2ccccc12 CHEMBL482355 Ki 4.9 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(N(C)C)c2ccccc12 CHEMBL481716 Ki 4.9 nM
O=C1CC2(CCSCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1084558 IC50 4.9 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(C(N)=O)CC1 CHEMBL2018666 Ki 4.9 nM
CCCCC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL2436757 Ke 4.9 nM
Cc1c(F)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4760014 Ki 4.9 nM
CC(=O)Nc1c(C(C)=O)c(=O)n(C)c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL204232 EC50 4.9 nM
Cc1c(C(=O)NN2CC3CCCC3C2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL15528 Ki 5.0 nM
Cn1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL369097 EC50 5.0 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL247978 Ki 5.0 nM
Cc1ccc(-c2ncc(C(=O)NC(C)CCc3ccccc3)nc2-c2ccc(C)cc2)cc1 CHEMBL247515 Ki 5.0 nM
Cc1c(C(=O)NC2CCCc3ccccc32)oc2ccc(S(=O)(=O)N3CC(C)CC(C)C3)cc12 CHEMBL272139 Ki 5.0 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)CO)c2)CC1 CHEMBL519389 IC50 5.0 nM
O=C(C1CC1)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL445204 EC50 5.0 nM
Cc1c(-c2cn(C3CCC3)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL579196 Ki 5.0 nM
N#Cc1ccc(C(=O)NC[C@@H]2CC[C@@H](c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)cc1 CHEMBL591542 Ki 5.0 nM
Cn1cc(Cc2cccc(-c3cccc4c3OCO4)n2)c2cc(NC(=O)CC(C)(C)O)ccc21 CHEMBL1224615 IC50 5.0 nM
C=CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCSC1)CC2 CHEMBL1950334 EC50 5.0 nM
O=C(NCC1CCOCC1)c1ncccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12 CHEMBL2316379 IC50 5.0 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccc(C#N)cc3)c(=O)n(Cc3ccc(C#N)cc3)n2c1=O CHEMBL3260751 Ki 5.0 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccc(CO)nc3)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260752 Ki 5.0 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)C1=C2C[C@@H](C)CC1 CHEMBL3329945 Ki 5.0 nM
COc1ccc(/C=C2\CN(C(=O)Cn3ccnc3)Cc3c(C(=O)N[C@H](C)c4ccccc4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 CHEMBL3893586 EC50 5.0 nM
CC(C)(C)OC(=O)CN1CCC(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)CC1 CHEMBL3966822 EC50 5.0 nM
FC(F)(F)c1ccccc1CN1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4225928 Ke 5.0 nM
Cc1ccc(CN2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cc1 CHEMBL4227115 Ke 5.0 nM
O=C(Nc1ccc(F)c(F)c1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4238830 Ke 5.0 nM
O=S(=O)(C1CC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4249248 Ki 5.0 nM
O=C(C1COc2ccccc2O1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4237291 Ki 5.0 nM
O=C(NC1CCCC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4245429 Ki 5.0 nM
O=C(Nc1ccc(F)cc1F)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4245076 Ki 5.0 nM
O=c1cc(NC2CCN(S(=O)(=O)C(F)(F)F)CC2)c2cc(C(c3ccc(Cl)cc3)n3ccnc3)ccc2[nH]1 CHEMBL4284299 EC50 5.0 nM
O/N=C(\c1ccc(F)cc1)C1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4519332 Ki 5.0 nM
O=S(=O)(NC1CCCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4476491 Ki 5.0 nM
O=S(=O)(NCc1ccc(-c2ccccc2)cc1)c1cc2ccc(F)cc2[nH]1 CHEMBL4447746 IC50 5.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)nc2)cc1)c1cc2ccc(Cl)cc2[nH]1 CHEMBL4569725 IC50 5.0 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cc(-c4ccco4)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353450 Ki 5.0 nM
C/N=C(\NS(=O)(=O)c1ccccc1Cl)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL348550 pA2 5.012 nM
COc1ccc(S(=O)(=O)NC(=N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)cc1 CHEMBL158610 pA2 5.012 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)n1 CHEMBL558785 pA2 5.012 nM
C/N=C(\NS(=O)(=O)N(C)C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL372650 pA2 5.012 nM
C/N=C(\NS(=O)(=O)N(C)C(C)C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL371829 pA2 5.012 nM
CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCC(=O)NC2CC2)c1 CHEMBL490648 pKi 5.012 nM
CN/C(=N\S(=O)(=O)c1cccc(Cl)c1)C1=NN(c2ccc(Cl)cc2Cl)C(c2ccccc2)C1 CHEMBL1081304 pA2 5.012 nM
COCCN1[C@H](C)CN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)C[C@@H]1C CHEMBL1209807 pEC50 5.012 nM
CCc1cccc2c(-c3nsc(CN4CCCC4)n3)cn(CC3CCOCC3)c12 CHEMBL1762798 pEC50 5.012 nM
CC(C)(O)CCNC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1 CHEMBL1760663 pKi 5.012 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(Br)cc3)cc1OC2(C)C CHEMBL487463 Ki 5.03 nM
C[C@H](NS(=O)(=O)c1cc(F)cc(F)c1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL230716 IC50 5.1 nM
CCc1c(C2=NC(=S)C(C)(C)N2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL498746 EC50 5.1 nM
CCc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CCC(C)C)s1 CHEMBL517116 IC50 5.1 nM
N#Cc1ccc(C(=O)NCC[C@@H]2CC[C@@H](c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)cc1 CHEMBL591067 Ki 5.1 nM
CC(C)C(=O)N[C@H]1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1 CHEMBL2063238 Ki 5.1 nM
C[S+]([O-])Cc1ccc(C(=O)Nc2ccc(OCCOCCO)nc2C(=O)NCC2CCC2)c2ccccc12 CHEMBL2316386 EC50 5.1 nM
COCCOc1ncc(C(=O)N[C@@H]2CCCC[C@H]2O)cc1-c1ccc(Cl)cc1 CHEMBL3109772 Ki 5.1 nM
Cc1cc(S(=O)(=O)N2CCc3c(nc(C(C)(C)C)n3CC3CC3)C2)no1 CHEMBL4640987 EC50 5.1 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CCCO[N+](=O)[O-])cc1 CHEMBL5267903 K 5.1 nM
CC(O)C1(CNC(=O)c2cc3cc(C#N)ccc3n2Cc2cccc(OC(F)(F)F)c2)CCCC1 CHEMBL1760644 pIC50 5.129 nM
COc1ccc(OC(F)(F)F)cc1Cn1c(C(=O)NCC2(CO)CC2)cc2cc(C#N)ccc21 CHEMBL1760656 pIC50 5.129 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL5188087 Ki 5.15 nM
Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1Cl CHEMBL361557 IC50 5.2 nM
CCCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCC1CCCCC1 CHEMBL180394 IC50 5.2 nM
CC(=O)Nc1c(C(C)=O)c(=O)n(CC2CCCO2)c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL202064 IC50 5.2 nM
CCCCCc1cc(O)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL225506 Ki 5.2 nM
CCCCCc1ccc(OCCCCCCCCCCC(=O)NC2CC2)cc1O CHEMBL229872 Ki 5.2 nM
CCCCCCC(C)(C)c1ccc(-c2ccccc2N)c(O)c1 CHEMBL234897 Ki 5.2 nM
Cc1c(-c2ncc(C(C)C)[nH]2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL568230 Ki 5.2 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1cnn(-c3ccc(Cl)cc3Cl)c1-2 CHEMBL4527391 Ki 5.2 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(F)c3)cc1OC2(C)C CHEMBL512531 Ki 5.26 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCCl CHEMBL151167 Ki 5.3 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL498527 Ki 5.3 nM
O=C(NC1CCC(F)(F)CC1)c1cnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1 CHEMBL606757 IC50 5.3 nM
CC1=CCC2C(C1)c1c(O)cc(CC#CCCC[N+](=O)[O-])cc1OC2(C)C CHEMBL160099 Kd 5.34 nM
CC(C)(CO)CNC(=O)c1cc2cc(C#N)ccc2n1Cc1cc(Cl)cc(Cl)c1 CHEMBL1760648 pIC50 5.37 nM
CC(=O)Nc1c(C(=O)C(C)(C)O)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL1092168 IC50 5.4 nM
N/C(=N\C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(Cl)cc1 CHEMBL5071344 IC50 5.4 nM
Cc1c(C(=O)NCCCCCCCCCNCCCCCCCCCN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269773 Ki 5.44 nM
CN1CCCCC1Cn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL571330 pKi 5.495 nM
COc1ccc(OC(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)O)cc2cc(C#N)ccc21 CHEMBL1760661 pKi 5.495 nM
COc1ccc(-c2c(C)c3c(n2-c2ccc(Cl)cc2Cl)CCN(C2CCCCC2)C3=O)cc1OC CHEMBL230782 Ki 5.5 nM
CC(C)(C)C(=O)c1oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2c1N CHEMBL1089351 IC50 5.5 nM
CCN(CC)S(=O)(=O)/N=C(/N=C(\N)c1ccc(F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5075684 Ki 5.5 nM
C[C@H](CO)NC(=O)CCC/C=C\C/C=C\CCOc1cccc(C(C)(C)CCCC#N)c1 CHEMBL393344 Ki 5.51 nM
Cc1c(C(=O)NCCCCCCCCCCCN(C)CCCCCCCCCCCN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269776 Ki 5.51 nM
CN(C)NC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1ccc(F)c(F)c1 CHEMBL247308 IC50 5.6 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL272203 Ki 5.6 nM
Cc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C CHEMBL575382 Ki 5.6 nM
Cc1c(C(=O)NC2CCCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL576549 Ki 5.6 nM
CN(Cc1ccc(F)cc1)C(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC#N CHEMBL592770 IC50 5.6 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(Cl)ccc1Cl CHEMBL1909858 Ki 5.6 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1-n1nnc2ccccc21 CHEMBL394736 IC50 5.7 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCCNC(=O)C1CCC1 CHEMBL247910 IC50 5.7 nM
N#CCc1c(C(=O)N2CCc3ccccc3C2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL602507 IC50 5.7 nM
N#CCc1c(C(=O)N2Cc3ccc(F)cc3C2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL592767 IC50 5.7 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C(=O)O)C[C@@H]21 CHEMBL456341 Ki 5.7 nM
CCCCCn1cc(C(=O)c2ccc(C(=O)CC)c3ccccc23)c2ccccc21 CHEMBL4549096 Ki 5.71 nM
Cc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)nn(CCCCSC#N)c1-c1ccccc1 CHEMBL5268104 K 5.76 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1cccc(Cl)c1 CHEMBL2113009 IC50 5.8 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2c(F)cccc2F)cc1 CHEMBL246350 Ki 5.8 nM
O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(-c3cccnc3)cc2)c1CO CHEMBL412071 Ki 5.8 nM
CCC(CC)NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC#N CHEMBL589643 IC50 5.8 nM
S=C(NC1CCCCC1)c1cnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1 CHEMBL611057 IC50 5.8 nM
O=S(=O)(NCC[C@@H]1CC[C@@H](c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1)c1cccnc1 CHEMBL603529 Ki 5.8 nM
O=C(C1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL1087644 Ki 5.8 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCCCCCO CHEMBL2018659 Ki 5.8 nM
CNC(=O)C(C)(C)NC(=O)c1ccc(N2CCC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3971011 EC50 5.8 nM
CC(C)(CCCCCCN=C=S)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL5085420 EC50 5.8 nM
Cc1cc(Cl)ccc1-c1c(C)c(C(=O)NN2CCCCC2)nn1-c1ccc(Cl)cc1Cl CHEMBL484505 Ki 5.83 nM
CC(C)(C)C#Cc1nc(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)cc1C#N CHEMBL246899 IC50 5.9 nM
CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(C#N)cc3)cc2c2n[nH]c(=O)n12 CHEMBL512436 IC50 5.9 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2cc(Cl)ccc2Cl)CC1 CHEMBL1087874 Ki 5.9 nM
O=C(N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1)C12CC3CC(CC(C3)C1)C2 CHEMBL1095690 Ki 5.9 nM
C[S+]([O-])Cc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCC2)c2ccccc12 CHEMBL2316109 EC50 5.9 nM
COCc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCC2)c2ccccc12 CHEMBL2316406 EC50 5.9 nM
CCCCCc1cccc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL4646867 Ki 5.9 nM
CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2c2cccc(O)c2)c(O)c1 CHEMBL5429198 EC50 5.9 nM
Cc1c(C(=O)NCC23CC4CC(CC(C4)C2)C3)nn(CCCCCCl)c1-c1ccccc1 CHEMBL2296777 pKi 5.984 nM
O=C(NC1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1CO CHEMBL2296781 pKi 5.998 nM
CCCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccccc1 CHEMBL426601 IC50 6.0 nM
CC(C)c1nc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c(=O)n1CC(F)(F)F CHEMBL201582 Ki 6.0 nM
Cc1ccc(-c2ncc(C(=O)NN3CCCCC3)nc2-c2ccc(C)cc2)cc1 CHEMBL226223 IC50 6.0 nM
Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1ccc(F)cc1)CCN(C1CCCCC1)C2=O CHEMBL396799 Ki 6.0 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(O)cc(C(F)(F)F)c2)CC1 CHEMBL522115 IC50 6.0 nM
O=C(C1CCCCC1)N1CCN(S(=O)(=O)c2cccc(-c3ccccc3)c2)CC1 CHEMBL490043 EC50 6.0 nM
CC(C)(C)c1nc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2c(=O)[nH]1 CHEMBL512957 IC50 6.0 nM
O=S(=O)(NC[C@@H]1CC[C@@H](c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1)c1cccnc1 CHEMBL591540 Ki 6.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCC/C2=C\c1ccc(F)cc1)c1ccccc1 CHEMBL3956678 EC50 6.0 nM
COc1ccc(/C=C2\CN(C(=O)CCS(N)(=O)=O)Cc3c(C(=O)N[C@H](C)c4ccccn4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 CHEMBL3924597 EC50 6.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)c(Cl)c2)c2c1CN(C(=O)Cn1cncn1)C/C2=C\c1ccc(Cl)cc1)c1ccccn1 CHEMBL3915613 EC50 6.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CN(C(=O)Cn1cnnn1)C/C2=C\c1ccc(F)cc1)c1ccccn1 CHEMBL3947225 EC50 6.0 nM
COc1ccc(/C=C2\CN(C(=O)Cn3cnnn3)Cc3c(C(=O)N[C@H](C)c4ccccc4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 CHEMBL3939540 EC50 6.0 nM
CC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL3913776 Ki 6.0 nM
O=c1cc(NC2CCN(c3ccccc3)CC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3936997 EC50 6.0 nM
O=c1cc(NC2CCN(c3ccccn3)CC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3894420 EC50 6.0 nM
COCCNc1cc(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc2c(NC3CCN(S(=O)(=O)C(F)(F)F)CC3)cc(=O)[nH]c12 CHEMBL3920667 EC50 6.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(Cc5ccncc5)CC4)ncnc32)cc1 CHEMBL4225661 Ke 6.0 nM
O=C(Nc1ccccn1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4241316 Ki 6.0 nM
CC1(NC(=O)Nc2ccc(F)cc2F)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4453295 Ki 6.0 nM
COCCOC(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4575677 Ke(app) 6.0 nM
O=S(=O)(NCc1ccc(-c2ccccc2)cc1)c1cc2cc(Br)ccc2[nH]1 CHEMBL4476181 IC50 6.0 nM
N/C(=N/C(=N/S(=O)(=O)N1CCCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(Cl)cc1 CHEMBL5089095 IC50 6.0 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cccnc3n(CCCCF)c2=O)CC1 CHEMBL5173890 Ki 6.0 nM
O=C(O)Cc1c(C(=O)N2CCC(Oc3ccc(F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5402791 IC50 6.0 nM
N#Cc1ccc2c(c1)cc(C(=O)NCCC(O)(C(F)(F)F)C(F)(F)F)n2Cc1cccc(OC(F)(F)F)c1 CHEMBL1760667 pIC50 6.026 nM
CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12 CHEMBL244403 EC50 6.1 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc(S(=O)(=O)c3ccccc3)cc21 CHEMBL507019 Ki 6.1 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CCCc2ccccc2)s1 CHEMBL522824 IC50 6.1 nM
O=C(NCC1CCC1)c1ncccc1NC(=O)c1cccc2ccccc12 CHEMBL2316397 IC50 6.1 nM
CC(C)(C)c1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL511907 pIC50 6.166 nM
CCN(CC(=O)NC1CC1)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1 CHEMBL2029722 EC50 6.2 nM
CS(=O)(=O)NC1(c2ccccc2)CCC(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL3971453 Ki 6.21 nM
Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1 CHEMBL4102969 Ki 6.28 nM
Cc1ccc(-c2cc(C#N)c(OCc3ccc(F)c(F)c3)nc2-c2ccc(Cl)cc2Cl)cc1 CHEMBL181629 IC50 6.3 nM
Cc1c(C2=NC(=S)C(C)(C)N2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL524634 IC50 6.3 nM
CC(C)CNS(=O)(=O)[C@@H]1CC[C@@H](c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1 CHEMBL600064 Ki 6.3 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCCCO CHEMBL2018658 Ki 6.3 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)NC1(C(F)(F)F)CCCC1 CHEMBL4590515 Ki 6.3 nM
Cc1c(C(=O)NN2CCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL369205 pA2 6.31 nM
Cc1c(C(=O)NOC(C)(C)C)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL360138 pA2 6.31 nM
O=C(NN1CCCCC1)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1 CHEMBL15399 pA2 6.31 nM
CCN(C)S(=O)(=O)N/C(=N\C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL364300 pA2 6.31 nM
CCCCNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)c(Cl)c1)c1ccccc1S2 CHEMBL485177 pIC50 6.31 nM
CCc1c(C(=O)NCCCCCCCNc2c3c(nc4ccccc24)CCCC3)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 CHEMBL567532 pA2 6.31 nM
CN/C(=N\S(=O)(=O)N1CCC(C(F)(F)F)CC1)C1=NN(c2ccc(Cl)cc2)[C@H](c2ccccc2)C1 CHEMBL1080157 pA2 6.31 nM
C[S+]([O-])c1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL1088223 pA2 6.31 nM
C[C@@H]1CN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)C[C@H](C)N1C CHEMBL1209645 pEC50 6.31 nM
C[C@@H]1CN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)C[C@H](C)N1CCO CHEMBL1209806 pEC50 6.31 nM
COCCN(C)Cc1csc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)n1 CHEMBL1762805 pEC50 6.31 nM
CCc1sc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)nc1CN(C)CCO CHEMBL1762813 pEC50 6.31 nM
CCCCCn1cc(C(=O)c2ccccc2-c2ccccc2)c2ccccc21 CHEMBL1828801 pKi 6.31 nM
COc1cccc2c(-c3nsc(CN4CCN(CC(N)=O)CC4)n3)cn(CC3CCOCC3)c12 CHEMBL2017678 pKi 6.31 nM
Cc1c(C(=O)NCCCCCN(C)CCCCCNC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1269769 Ki 6.35 nM
CCCCCC1=NN(C(=O)NC2C3CC4CC(C3)CC2C4)CC1c1ccccc1 CHEMBL1224630 Ki 6.4 nM
Cc1c(C(=O)NC2CCN(C(=O)OC(C)C)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL3759785 Ki 6.4 nM
C=CCc1ccc(O)c(-c2ccc(O)c(CC=C)c2)c1 CHEMBL16901 Ki 6.46 nM
Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1ccc(Cl)cc1)CCN(C1CCCCC1)C2=O CHEMBL396798 Kb 6.5 nM
CC1(C)CC(NC(=O)C2(O)CC2)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 CHEMBL1095499 IC50 6.5 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2c(F)cccc21 CHEMBL4438072 Ki 6.5 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCC1CCOC1 CHEMBL397119 IC50 6.6 nM
CCc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(C)ccc1C CHEMBL1909852 Ki 6.7 nM
COc1cccc(-c2c(C)c3c(n2-c2ccc(Cl)cc2Cl)CCN(C2CCCCC2)C3=O)c1 CHEMBL230678 IC50 6.8 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C34CC5CC(CC(C5)C3)C4)cc1OC2(C)C CHEMBL434351 Ki 6.8 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nn(CCN2CCOCC2)c2ccccc12 CHEMBL2338173 Ki 6.8 nM
O=C(Nc1ccc(Cl)cc1)Nc1ccc(-c2ccccc2)s1 CHEMBL4527602 IC50 6.8 nM
Cc1c(C(=O)N[C@H]2CCCC[C@@H]2O)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 CHEMBL395026 Ki 6.9 nM
CNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccccc1 CHEMBL426241 IC50 7.0 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1ccc(Cl)cc1 CHEMBL391556 IC50 7.0 nM
C[C@H](NCC(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL245957 Ki 7.0 nM
O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1)(c1ccc(F)cc1)O2)N1CCCCC1 CHEMBL409472 Ki 7.0 nM
CC1CN(S(=O)(=O)c2cccc3ccccc23)CCN1C(=O)C1CCCCC1 CHEMBL522262 EC50 7.0 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-n3cncn3)cc(C(F)(F)F)c2)CC1 CHEMBL487294 IC50 7.0 nM
N#CCc1c(C(=O)NCc2c(Cl)cccc2Cl)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL590137 IC50 7.0 nM
CC(C)(CO)C(=O)Nc1ccc2ccn(Cc3cccc(-c4cccc5c4OCO5)n3)c2c1 CHEMBL1224534 IC50 7.0 nM
Cn1cc(Cc2cccc(-c3cccc4c3OCO4)n2)c2cc(NC(=O)C(C)(C)CO)ccc21 CHEMBL1224613 IC50 7.0 nM
O=C(N1CCCCC1)N1CC(O[C@H](c2ccc(Cl)cc2)c2cccnc2Cl)C1 CHEMBL558709 Ki 7.0 nM
Cc1c(C(=O)N[C@@H]2CCCN(S(C)(=O)=O)C2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL2030933 Ke 7.0 nM
C[C@@H](O)[C@H](N/C(=N/S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O CHEMBL2153674 IC50 7.0 nM
C[C@@H](O)[C@H](N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(=O)N[C@@H](CO)C(N)=O CHEMBL2153772 IC50 7.0 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2c2ncc(C(F)(F)F)cc2Cl)no1 CHEMBL3400943 EC50 7.0 nM
Cc1c(C(=O)NC2CCN(C(=O)c3ccccc3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL3758884 Ke 7.0 nM
O=C(NC1(c2ccccn2)CC1)c1nn(-c2ccc(Cl)cc2)c2c1CCC/C2=C\c1ccc(Cl)cc1 CHEMBL3930886 EC50 7.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCC/C2=C\c1ccc(Cl)cc1)c1ccccn1 CHEMBL3904447 EC50 7.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)c(Cl)c2)c2c1CN(C(=O)Cn1cnnn1)C/C2=C\c1ccc(F)cc1)c1ccccn1 CHEMBL3976516 EC50 7.0 nM
O=c1cc(Nc2ccc(C(F)(F)F)cc2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3909066 EC50 7.0 nM
O=c1cc(NCc2cccc(C(F)(F)F)c2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3900016 EC50 7.0 nM
O=c1cc(NCc2ccc(C(F)(F)F)nc2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3931509 EC50 7.0 nM
O=c1cc(NC2CCCCC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 CHEMBL3894586 EC50 7.0 nM
N#CC(c1ccccc1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4225446 Ki 7.0 nM
CC1(NC(=O)NC2CCCCC2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4532150 Ke 7.0 nM
CC1(NC(=O)NS(=O)(=O)c2ccccc2F)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4464256 Ke 7.0 nM
O=C(Nc1ccccc1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4462028 Ki 7.0 nM
O=S(=O)(NCc1ccc(-c2cccnc2)cc1)c1cc2ccccc2[nH]1 CHEMBL4521762 IC50 7.0 nM
Cc1cc(S(=O)(=O)N2CCc3c(nc(CC(C)(C)C)n3CC3CC3)C2)no1 CHEMBL4647333 EC50 7.0 nM
O=C(O)Cc1c(C(=O)N2CCC(Oc3ccc(C(F)(F)F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5429508 IC50 7.0 nM
C[C@H](NS(=O)(=O)c1ccc(Cl)cc1Cl)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL230923 IC50 7.1 nM
O=C(N[C@H]1CCCC[C@@H]1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 CHEMBL229914 Kb 7.1 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CC2CCCC2)s1 CHEMBL493302 IC50 7.1 nM
CN(CCCC(=O)NC1CC1)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1 CHEMBL2029718 Ki 7.1 nM
N#Cc1cc(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL180409 IC50 7.2 nM
Cc1ccc(-c2nc(C(=O)NC3CCCCC3)cn2-c2ccc(Cl)cc2)c(C)c1 CHEMBL229698 Ki 7.2 nM
CCCCCn1cc(C(=O)c2ccc(F)c3ccccc23)c2ccccc21 CHEMBL2206855 Ki 7.2 nM
CCCCCn1nc(C(=O)NC(C)(C)C)cc1C(C)(C)C CHEMBL4787118 EC50 7.2 nM
C=CCNC(=O)CCCCCCCOc1cc(O)cc(C(C)(C)CCCCCC)c1 CHEMBL3323682 Ki 7.22 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCC CHEMBL429055 Ki 7.3 nM
Cc1ccccc1-c1nc(C(=O)NC2CCCCC2)cn1-c1ccc(Cl)cc1 CHEMBL439375 Kb 7.3 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CC2CCCCC2)s1 CHEMBL494728 IC50 7.3 nM
COC(=O)C(NC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1CC#N)C(C)C CHEMBL589161 IC50 7.3 nM
C[C@H](NS(=O)(=O)c1cc(Cl)ccc1Cl)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL389114 IC50 7.4 nM
CC(C)(C)c1nc(O)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 CHEMBL466470 IC50 7.4 nM
CCCCCC1=NN(C(=O)Nc2cccc3ccccc23)CC1c1ccccc1 CHEMBL1224690 Ki 7.4 nM
CC(C)(C)Cn1nc(C(=O)NC(C)(C)c2ccccc2)c2c1[C@@H]1C[C@@H]1C2 CHEMBL3354937 EC50 7.4 nM
C/C(N)=N/C(=N/S(=O)(=O)N1CCCC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL5081757 Ki 7.4 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CC[C@@H](C)C(=O)N[C@H](C)CO CHEMBL121174 Ki 7.42 nM
COc1ccc(-c2c(C)c3c(n2-c2ccccc2Cl)CCN(C2CCCCC2)C3=O)cc1 CHEMBL231096 Ki 7.5 nM
COc1nc(C(C)(C)C)nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL513121 IC50 7.5 nM
COc1ccc(C(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)O)cc2cc(C#N)ccc21 CHEMBL1760662 pKi 7.586 nM
Cc1c(-c2cn(C(C)C)cn2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL584261 Ki 7.6 nM
C=CCNC(=O)CCCCCCCOc1cc(OC)cc(C(C)(C)CCCCCC)c1 CHEMBL4639040 Ki 7.6 nM
Cc1cc(C(=O)N[C@H]2CC(C)(C)Oc3nc(-c4ccc(Cl)cc4Cl)c(-c4ccc(Cl)cc4)cc32)n[nH]1 CHEMBL1095806 IC50 7.65 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1cccc1Cl CHEMBL1909844 Ki 7.7 nM
O=C(NN1CCCCC1)c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1 CHEMBL160963 Ki 7.8 nM
Cc1c(C(=O)NN2CC3CCCC3C2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C#CC2CCCCC2)s1 CHEMBL524158 IC50 7.8 nM
N#CCc1c(C(=O)N[C@@H]2c3ccccc3C[C@@H]2O)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL592525 IC50 7.8 nM
O=C(NC(CO)(CO)CO)c1ccc(S(=O)(=O)N2CCC(Nc3ncnc4ccc(C(c5ccc(Cl)cc5)c5ccc(Cl)cc5)cc34)CC2)cc1 CHEMBL4741756 EC50 7.8 nM
COc1ccc(-c2c(C)c3c(n2-c2ccc(Cl)cc2Cl)CCN(C2CCCCC2)C3=O)cc1 CHEMBL230572 Ki 7.9 nM
CCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CC4CCCC4C3)nn2-c2ccc(Cl)cc2Cl)s1 CHEMBL460131 IC50 7.9 nM
Cc1c(-c2cn(C3CC3)cn2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL583229 Ki 7.9 nM
CCCCCc1c(C(=O)NCCc2ccc(C(=O)c3ccccc3)cc2)[nH]c2ccc(Cl)cc12 CHEMBL4781722 EC50 7.9 nM
O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)s1 CHEMBL177403 pA2 7.943 nM
C/N=C(\NS(=O)(=O)N1CCS(=O)(=O)CC1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 CHEMBL425912 pA2 7.943 nM
O=S(=O)(/N=C(\NCCCCNc1c2c(nc3ccccc13)CCCC2)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(Cl)cc1 CHEMBL571730 pA2 7.943 nM
CCCCC1=NN(C(=O)NC(C)(C)c2ccccc2)C(C)(C)C1c1ccccc1 CHEMBL1223716 pEC50 7.943 nM
CCCCCN1N=C(C(=O)NC2C3CC4CC(C3)CC2C4)CC1c1ccccc1 CHEMBL1223776 pEC50 7.943 nM
CCCCCn1cc(C(=O)c2cccc(-c3ccccc3)c2)c2ccccc21 CHEMBL1828800 pKi 7.943 nM
CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2-c2cc(CO)ccc21 CHEMBL2348473 EC50 7.97 nM
COc1cccc2c(C(=O)NC3C(C)(C)[C@@H]4CC[C@@]3(C)C4)c(C)n(CCN3CCOCC3)c12 CHEMBL431363 Ki 8.0 nM
Cn1c(C(=O)NC2CCCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL181096 IC50 8.0 nM
N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)nc1OCc1ccc(F)c(F)c1 CHEMBL179787 IC50 8.0 nM
COc1ccc(-c2ncc(C(=O)NC3CCCCC3)nc2-c2ccc(OC)cc2)cc1 CHEMBL227840 IC50 8.0 nM
CC(C)(O)c1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)[C@@H]3C[C@H]3c3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL490027 IC50 8.0 nM
C[C@@H]1CN(S(=O)(=O)c2cccc3ccccc23)C[C@H](C)N1C(=O)C1CCCCC1 CHEMBL504182 EC50 8.0 nM
CCC(=O)Oc1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)[C@@H]3C[C@H]3c3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL488932 IC50 8.0 nM
CC(C)(C)C(=O)Oc1cc(C(F)(F)F)cc(S(=O)(=O)N2CCN(C(=O)[C@@H]3C[C@H]3c3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL488731 IC50 8.0 nM
CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c2nncn12 CHEMBL467924 IC50 8.0 nM
CC(C)(C)OC(=O)N1CCN(C[C@@H]2CC[C@@H](c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)CC1 CHEMBL601936 Ki 8.0 nM
Cc1c(C(=O)NC[C@H]2CC[C@@H](CNS(C)(=O)=O)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL1834021 Ki 8.0 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(O)CC1 CHEMBL2018664 Ki 8.0 nM
C[C@H](N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(=O)N[C@@H](CO)C(N)=O CHEMBL2153767 IC50 8.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(C(F)(F)F)cc2Cl)c2c1CCCC/C2=C\c1ccc(Cl)s1)c1ccccn1 CHEMBL3938215 EC50 8.0 nM
O=C(NC1(c2ccccn2)CC1)c1nn(-c2ccc(C(F)(F)F)cc2Cl)c2c1CCCC/C2=C\c1ccc(Cl)s1 CHEMBL3941829 EC50 8.0 nM
COc1ccc(/C=C2\CN(C(=O)CS(N)(=O)=O)Cc3c(C(=O)N[C@H](C)c4ccccn4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 CHEMBL3896570 EC50 8.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CN(C(=O)Cn1cnnn1)C/C2=C\c1ccc(F)cc1)c1ccccc1 CHEMBL3920504 EC50 8.0 nM
COc1ccc(C(c2ccc(Cl)cc2)c2ccc3[nH]c(=O)cc(NC4CCN(S(=O)(=O)C(F)(F)F)CC4)c3c2)cc1 CHEMBL3910177 EC50 8.0 nM
Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(N4CCN(Cc5ccccc5Cl)CC4)ncnc32)cc1 CHEMBL4225349 Ki 8.0 nM
Cc1c(CN2CCN(c3ncnc4c3nc(-c3ccccc3Cl)n4-c3ccc(Cl)cc3)CC2)cnn1C CHEMBL4225343 Ki 8.0 nM
O=C(CC1CCOC1)N1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4240555 Ki 8.0 nM
O=C(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(C(F)(F)F)nc2)CC1)c1ccccc1 CHEMBL4520766 Ki 8.0 nM
COc1ccc2[nH]c(S(=O)(=O)NCc3ccc(-c4ccc(C#N)cc4)cc3)cc2c1 CHEMBL4516158 IC50 8.0 nM
Cc1c(S(=O)(=O)NCc2ccc(-c3ccccc3)cc2)[nH]c2ccccc12 CHEMBL4589557 IC50 8.0 nM
O=C(O)Cc1c(C(=O)N2CCC(Oc3ccc(Cl)cc3F)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5399473 IC50 8.0 nM
O=C(O)Cc1c(C(=O)N2CCC(Oc3cc(F)cc(F)c3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL5404036 IC50 8.0 nM
O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(F)cc2Cl)CC1 CHEMBL1086605 Ki 8.1 nM
O=[N+]([O-])CC(c1ccccc1)c1c(-c2ccccc2)[nH]c2ccccc12 CHEMBL4450922 EC50 8.1 nM
N#Cc1ccc2c(c1)cc(C(=O)NCCC(O)C(F)(F)F)n2Cc1cccc(OC(F)(F)F)c1 CHEMBL1760666 pIC50 8.128 nM
O=C(NC1CCCCC1)c1cn(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2Cl)n1 CHEMBL229584 Ki 8.2 nM
O=C1CC2(CCCCC2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21 CHEMBL1084557 IC50 8.2 nM
Cc1ncsc1C(=O)NC1(C(=O)N[C@H](C)c2ccc(-n3nc(Cl)c4ccccc43)cc2F)CC1 CHEMBL1801339 Ki 8.2 nM
CCOC(=O)c1ccc(CNC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)cc1 CHEMBL4568756 Ki 8.2 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C3(C#N)CCCCC3)cc1OC2(C)C CHEMBL205888 Ki 8.26 nM
NC(=O)[C@@H](N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C1CCC1 CHEMBL2153673 IC50 8.3 nM
CCOc1ccc(OC(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)CO)cc2cc(C#N)ccc21 CHEMBL1760647 pIC50 8.318 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(OC(=O)CCCN3CCOCC3)cc(C(C)(C)CCCCC#N)cc1OC2(C)C CHEMBL1668516 Ki 8.4 nM
CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccncc3C)c(=O)n(Cc3ccc(C(F)(F)F)nc3C)n2c1=O CHEMBL3260744 Ki 8.4 nM
CN(C)c1nc(C(C)(C)C)nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 CHEMBL466294 IC50 8.5 nM
CC(C)(N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O CHEMBL2153666 IC50 8.5 nM
CCCCCCC(C)(C)c1cccc(OCC/C=C\C/C=C\CCCC(=O)N[C@H](C)CO)c1 CHEMBL391858 Ki 8.55 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1Cl CHEMBL1909856 Ki 8.6 nM
CCCCCn1c2c(c(O)c(C(=O)NC34CC5CC(CC(C5)C3)C4)c1=O)CCCC2 CHEMBL3780075 Kieq 8.7 nM
O=C(NC1CCCCCC1)c1cc(Br)cn(Cc2ccc(F)cc2)c1=O CHEMBL3114178 Ki 8.8 nM
CCCOC(=O)N1CCC(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)CC1 CHEMBL3759222 Ki 8.82 nM
C[C@H](CO)NC(=O)CCC/C=C\C/C=C\CCOc1cccc(C(C)(C)CCCCBr)c1 CHEMBL240314 Ki 8.87 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)C2CCCCC2)cc1 CHEMBL245975 Ki 8.9 nM
CCCCCn1c(C)c(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc21 CHEMBL2206860 Ki 8.9 nM
CC(O)CCNC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1 CHEMBL1760665 pIC50 8.913 nM
CCCCC#CCCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL161073 Kd 9.0 nM
N#Cc1c(C(=O)NN2CC3CCCC3C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 CHEMBL416718 Ki 9.0 nM
COc1ccc(-n2cc(C(=O)NC3CCCCC3)nc2-c2ccccc2Cl)cc1 CHEMBL229750 Ki 9.0 nM
O=C([C@@H]1C[C@H]1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(-c3cn[nH]c3)cc(C(F)(F)F)c2)CC1 CHEMBL519252 IC50 9.0 nM
Cc1c(-c2ncn(C(C)C)c2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL577040 Ki 9.0 nM
Cc1c(-c2cn(C(C)C)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL578576 Ki 9.0 nM
C=CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)CC2 CHEMBL1950333 Ki 9.0 nM
CC(C)CCn1c2c(cc(C(=O)NCc3ccccc3)c1=O)CCCCCC2 CHEMBL2387178 Ki 9.0 nM
C/C=C/C=C/C=C/CC/C=C/C(=O)NCC(C)(C)O CHEMBL2335715 IC50 9.0 nM
Cc1nc(C(F)(F)F)ccc1Cn1c(=O)c(-c2ccncc2)c(-c2ccc(Cl)cc2)c2nn(C)c(=O)n21 CHEMBL3260741 Ki 9.0 nM
CC1(C)C(=O)N(c2ccc(F)c(C(F)(F)F)c2)C(=O)C1Cc1ccc(F)cc1NC(=O)Nc1ccc(S(N)(=O)=O)cc1 CHEMBL3341900 Ki 9.0 nM
C[C@@H](NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CN(C(=O)CC(N)=O)C/C2=C\c1ccc(F)cc1)c1ccccn1 CHEMBL3905508 EC50 9.0 nM
CC1(NS(=O)(=O)NC2CCCCC2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4438188 Ki 9.0 nM
CCCCCS(=O)(=O)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4447876 Ki 9.0 nM
O=S(=O)(CC1CCCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 CHEMBL4520830 Ki 9.0 nM
O=S(=O)(NCc1ccc(-c2ccc(F)cc2)cn1)c1cc2cc(Br)ccc2[nH]1 CHEMBL4454441 IC50 9.0 nM
CC(C)CCNS(=O)(=O)[C@@H]1CC[C@@H](c2ccc(Cl)cc2Cl)N(c2ccc(Cl)cc2)C1 CHEMBL598125 Ki 9.1 nM
CCCCC(=O)N1CCC(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)CC1 CHEMBL3759440 Ke 9.1 nM
Cc1ccccc1N1CCN(CCCNC(=O)Oc2cccc3ccccc23)CC1 CHEMBL3798943 EC50 9.1 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCC(C#N)c3ccccc3)cc1OC2(C)C CHEMBL337536 Ki 9.2 nM
O=C(N[C@@H]1c2ccccc2C[C@@H]1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 CHEMBL395321 Kb 9.2 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(C#N)c2ccccc12 CHEMBL482357 Ki 9.2 nM
N#CCc1c(C(=O)N2CCC(c3ccc(F)cc3)C2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 CHEMBL590616 IC50 9.2 nM
Cc1c(C(=O)c2cccc3ccccc23)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL1222317 Ki 9.2 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(C#N)cc3)cc1OC2(C)C CHEMBL472115 Ki 9.25 nM
Cc1ccccc1-n1c2c(c(C)c1-c1ccc(C(F)(F)F)cc1)C(=O)N(C1CCCCC1)CC2 CHEMBL387609 IC50 9.3 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cccc2ccccc12 CHEMBL516406 Ki 9.3 nM
COc1ccc(Br)cc1Cn1c(C(=O)NCCCO)cc2cc(C#N)ccc21 CHEMBL1760670 pIC50 9.333 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(Cl)ccc1Cl CHEMBL1909846 Ki 9.4 nM
CC(C)(C)c1nc(NCC(F)(F)CO)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 CHEMBL513812 IC50 9.5 nM
Cc1c(-c2cnc(C(C)C)[nH]2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL565742 Ki 9.5 nM
Cc1c(C(=O)N[C@@H]2CCCC[C@H]2O)cc(-c2cc(C(F)(F)F)ccc2Cl)n1CC1CCCCC1 CHEMBL3109763 IC50 9.5 nM
CS(=O)(=O)N1CCC(NC(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CC(N)=O)CC1 CHEMBL5422722 IC50 9.5 nM
O=C(NC1CCCCCC1)c1cc2cccnc2n(Cc2ccc(F)cc2)c1=O CHEMBL467896 Ki 9.6 nM
CN(C)CCN1CCN(/C(=N\S(=O)(=O)c2ccc(Cl)cc2)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)CC1 CHEMBL570623 Ki 9.6 nM
C[C@H](NS(=O)(=O)c1ccccc1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL397243 IC50 9.7 nM
O=C(N[C@H]1CCC[C@@H]1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 CHEMBL229965 Kb 9.7 nM
C=Cc1ccc(-c2c(C)c3c(n2-c2ccc(Cl)cc2Cl)CCN(C2CCCCC2)C3=O)cc1 CHEMBL387782 Ki 9.8 nM
CCc1c(C2=NC(=O)C(C)(C)N2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL500689 EC50 9.8 nM
CCN(CC(=O)NCCF)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1 CHEMBL2029731 EC50 9.8 nM
COc1ccc(-c2cc(C(=O)NC3CCCCCC3)c(=O)n(Cc3ccc(F)cc3)c2C)cc1 CHEMBL4781965 Ki 9.8 nM
CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(Cl)cc3)c(-c3ccncc3)n2)CC1 CHEMBL522395 Ki 9.81 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2cc(F)ccc21 CHEMBL4519883 Ki 9.85 nM
Cc1c(C(=O)NC2CCN(S(=O)(=O)CC(C)C)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL3758491 Ke 9.9 nM