CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(CO)C[C@H]21 CHEMBL41721 Log Ki -0.66 nM
CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 CHEMBL559612 Log Ki -0.007 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccncc3)c(=O)[nH]c12 CHEMBL1822945 Ki 0.01 nM
CCCCCc1cc2cc(C(=O)OC)c(=O)[nH]c2c(O)c1OC CHEMBL1822939 Ki 0.014 nM
Fc1ccc(-c2noc(CCCNc3ccc4ncc(OC(F)(F)F)cc4c3)n2)c(Cl)c1 CHEMBL499066 EC50 0.015 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c12 CHEMBL600647 Ki 0.019 nM
CCOc1c(OC)ccc2cc(C(=O)NCCc3ccncc3)c(=O)[nH]c12 CHEMBL1822944 Ki 0.02 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)n(C)c12 CHEMBL3410832 pKi 0.02099 nM
CCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c12 CHEMBL1822940 Ki 0.021 nM
CCCC(C)(C)c1ccc2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL371214 Ki 0.023 nM
CCCCCOc1ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c2c1OCCCCC CHEMBL3410813 Ki 0.026 nM
CC(C)(C)CCCCCc1ccc2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL2112647 Ki 0.032 nM
CCCCCCC(C)(C)c1ccc2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL1277685 Ki 0.032 nM
CCCCOc1c(OC)ccc2cc(C(=O)O)c(=O)[nH]c12 CHEMBL1822946 Ki 0.032 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(OO)C[C@@H]21 CHEMBL3233404 Ki 0.032 nM
CCCCCc1cc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c2c(O)c1OC CHEMBL1822941 Ki 0.036 nM
Cc1ccc2c(c1)Cc1c(C(=O)NN3CCCCC3)nn(-c3ccc(Cl)cc3Cl)c1-2 CHEMBL216276 Ki 0.037 nM
CC(C)CCS(=O)(=O)C(C)(C)C(=O)Nc1cc(C(C)(C)C)no1 CHEMBL3234701 EC50 0.04 nM
CC(C)(C)c1cc(NC(=O)[C@]2(C)CCCN2c2ccc(C(F)(F)F)cn2)no1 CHEMBL3400946 EC50 0.04 nM
CCCCCc1cc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)n(C)c2c(O)c1OC CHEMBL1822942 Ki 0.043 nM
CCOc1c(OC)ccc2cc(C(=O)NCc3ccc4c(c3)OCO4)c(=O)[nH]c12 CHEMBL3410818 pKi 0.05297 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2c2ccc(C(F)(F)F)cn2)no1 CHEMBL3234706 EC50 0.067 nM
Cc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)nn(CCCCCO)c1-c1ccccc1 CHEMBL5266788 Ki 0.075 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)CC21 CHEMBL432107 EC50 0.078 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2c2ncc(C(F)(F)F)cc2Cl)no1 CHEMBL3400943 EC50 0.08 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NC(C)CO CHEMBL4177060 EC50 0.08 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCN3CCOCC3)c(=O)n(C)c12 CHEMBL1822943 pKi 0.08492 nM
CC1(C)C(C(=O)c2cn(CCCC(F)(F)F)c3ccccc23)C1(C)C CHEMBL569082 pKi 0.08511 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4c(c3)OCO4)c(=O)oc12 CHEMBL3410729 pKi 0.0869 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4c(c3)OCO4)c(=O)[nH]c12 CHEMBL178372 Ki 0.087 nM
CCCCCNc1c(OC)ccc2c1CN(CCc1ccc(O)cc1)C2=O CHEMBL3410826 pKi 0.0879 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4C)no3)ccc21 CHEMBL501472 EC50 0.089 nM
CCCOc1c(OC)ccc2cc(C(=O)NCCc3ccccc3)c(=O)[nH]c12 CHEMBL3410817 pKi 0.08995 nM
CCCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152813 Ki 0.09 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2c2ccc(C(F)(F)F)cn2)no1 CHEMBL3235059 EC50 0.09 nM
COc1cccc2c(C(=O)C3C(C)(C)C3(C)C)cn(CC3CCOCC3)c12 CHEMBL411631 Ki 0.1 nM
CCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152812 Ki 0.1 nM
CCCCn1c2c(cc(C(=O)NC(C)(C)c3ccccc3)c1=O)CCCCCC2 CHEMBL2387185 Ki 0.1 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(=O)OC CHEMBL3914627 EC50 0.1 nM
CCCCCOc1ccc2c(c1OCCCCC)CN(CCc1ccc(N)cc1)C2=O CHEMBL3410827 pKi 0.1099 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cc(Br)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353441 Ki 0.12 nM
CC1(C)C(C(=O)c2cn(CC3CCOC3)c3ccccc23)C1(C)C CHEMBL569994 Ki 0.14 nM
O=C(c1ccc(Cl)cc1)N1CC[C@](O)(c2ccccc2)[C@H]2CCCC[C@H]21 CHEMBL1765160 IC50 0.14 nM
Cc1ccc2c(C(=O)C3C(C)(C)C3(C)C)cn(CC3CCOCC3)c2c1 CHEMBL271839 Log Ki 0.1479 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@H]1CC=C(CO)C[C@H]21 CHEMBL334533 Ki 0.15 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL307696 Ki 0.15 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nn(CCN2CCOCC2)c2ccccc12 CHEMBL2338173 Ki 0.15 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C3(C(N)=O)CC3)ccc2n1CC1CC1 CHEMBL3234674 EC50 0.15 nM
CC1CCC(NC(=O)c2cc3cc(-c4cccs4)cnc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL3353452 Ki 0.17 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccccc3F)c(=O)[nH]c12 CHEMBL3410831 pKi 0.1799 nM
CC1(C)C(C(=O)c2cn(CCN3CCOC3=O)c3ccccc23)C1(C)C CHEMBL584742 Ki 0.18 nM
CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353439 Ki 0.18 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(O)c2nn(C)cc21 CHEMBL4649122 Ki 0.18 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCC(=O)N2c2ccc(C(F)(F)F)cn2)on1 CHEMBL3353885 EC50 0.19 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2c2ccc(Cl)cc2)no1 CHEMBL3353863 EC50 0.19 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=CC21 CHEMBL111148 Ki 0.199 nM
Cc1nc(C(=O)NCc2ccccc2C(F)(F)F)c(C)n1-c1ccccc1 CHEMBL598463 pEC50 0.1995 nM
O=C(c1c(NC(=O)C23CC4CC(CC2C4)C3)sc2c1CCOC2)N1CC(F)(F)C1 CHEMBL2010900 pIC50 0.1995 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL111724 Ki 0.2 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc2c1CCCC2 CHEMBL232116 Ki 0.2 nM
CC(C)(C)c1cc(NC(=O)CCc2nc(-c3ccc(F)cc3Cl)no2)no1 CHEMBL499060 EC50 0.2 nM
CCC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC1 CHEMBL596388 Ki 0.2 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL600602 Ki 0.2 nM
O=S(=O)(c1cc2ccccc2n1S(=O)(=O)c1ccccc1F)N1CCC(O)(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL1271092 Ki 0.2 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)OCCO1 CHEMBL108085 Ki 0.2 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)cc2ccccc21 CHEMBL1814468 Ki 0.2 nM
CCCCn1c2c(cc(C(=O)NC3CCCCC3)c1=O)CCCCCC2 CHEMBL2387183 Ki 0.2 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCCCC2)no1 CHEMBL3353864 EC50 0.2 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2CC2CCOCC2)no1 CHEMBL3354535 EC50 0.2 nM
CC(C)(NC(=O)c1nn(Cc2ccc(F)cc2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354941 EC50 0.2 nM
NC(=O)[C@H](CC1CC1)NC(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1 CHEMBL3942960 EC50 0.2 nM
NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1 CHEMBL3966532 EC50 0.2 nM
CCCCOC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](O)C[C@@H]21 CHEMBL4465566 Ki 0.2 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccccc23)C1(C)C CHEMBL271158 Ki 0.21 nM
CC(C)(C)c1cc(NC(=O)[C@]2(C)CCCN2c2ccc(Cl)cc2)no1 CHEMBL3400945 EC50 0.21 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4c(c3)OCO4)c(=O)n(C)c12 CHEMBL3410819 pKi 0.2198 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C3CCCCCC3)cc1OC2(C)C CHEMBL252949 Ki 0.22 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2c2ccc(C(F)(F)F)cc2)no1 CHEMBL3353862 EC50 0.23 nM
O=C(NC1CCCCCC1)c1cc2ccccc2n(Cc2ccc(F)cc2)c1=O CHEMBL2022363 Ki 0.25 nM
Cc1nc(C(C)(NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CC3)cn2)C2CC2)no1 CHEMBL3910524 EC50 0.25 nM
Cc1nc(C(C)(NC(=O)c2cc(O[C@H](C)C(F)(F)F)c(C3CC3)cn2)C2CC2)no1 CHEMBL4114424 EC50 0.25 nM
CCc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)nc(C)n1-c1ccccc1 CHEMBL600683 pEC50 0.2512 nM
CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C CHEMBL2170545 Ki 0.26 nM
CCC(C)Cn1c(C(C)(C)C)nc2cc(S(=O)(=O)c3ccnc(F)c3)ccc21 CHEMBL3234676 EC50 0.26 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)cc2cc(C(C)C)ccc21 CHEMBL3780550 Kieq 0.26 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccs3)cc1OC2(C)C CHEMBL519575 Ki 0.27 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cc(-c4ccco4)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353450 Ki 0.27 nM
COc1cc(C(O)c2cccs2)cc(OC)c1-c1cc(Cl)cc(Cl)c1 CHEMBL1076685 Ki 0.27 nM
Cc1c(C(=O)c2cccc3ccccc23)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL188 Ki 0.28 nM
Cc1cc(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)cn1CCCC(F)(F)F CHEMBL2170532 Ki 0.28 nM
Cc1ccc(Cn2nc(C(=O)NC3C4(C)CCC(C4)C3(C)C)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL381689 Ki 0.28 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CC1(Cl)Cl CHEMBL120669 Log Ki 0.2884 nM
CC(C)(C)c1cc(NC(=O)[C@]2(C)CCCN2c2ccc(C(F)(F)F)cc2)no1 CHEMBL3400944 EC50 0.29 nM
C=CCN1Cc2c(n(S(=O)(=O)CC)c3ccc(C(=O)N4CCC(C)CC4)cc23)C1 CHEMBL250608 EC50 0.3 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2cccc(Br)c2)n1CC1CC1 CHEMBL247996 EC50 0.3 nM
CCOc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL411504 EC50 0.3 nM
O=C(c1cccc(Cl)c1Cl)c1nc(CN2CCC(F)(F)CC2)c2ccccn12 CHEMBL1760932 IC50 0.3 nM
COC(=O)C(C)(C)NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2018655 Ki 0.3 nM
CCCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152803 Ki 0.3 nM
CC(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686329 Ki 0.3 nM
CC(CF)Oc1cc(C(=O)NC2(CC(N)=O)CS(=O)(=O)C2)ncc1C1CC1 CHEMBL3945954 EC50 0.3 nM
CCCCOC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL4470925 EC50 0.3 nM
CC1(C)Oc2cc(C3(CCCCCCCC#N)CCCC3)cc(O)c2[C@@H]2C[C@H](CN=[N+]=[N-])CC[C@H]21 CHEMBL5084325 Ki 0.3 nM
Cc1ccc(Cn2nc(C(=O)N[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL381791 Ki 0.31 nM
Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cccc(C(F)(F)F)c2F)n1CC1CCC1 CHEMBL264154 EC50 0.32 nM
CCCC1COc2cccc3c(=O)c(C(=O)NC4CCCCC4)cn1c23 CHEMBL2163935 Ki 0.32 nM
CCCCn1nc(C(C)(C)C)s/c1=N/C(=O)c1cc(C(F)(F)F)ccc1ONC(=O)OC(C)(C)C CHEMBL3650081 Ki 0.32 nM
CCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccccc3)c(=O)[nH]c12 CHEMBL3410815 pKi 0.3296 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4C#N)no3)ccc21 CHEMBL499324 EC50 0.33 nM
CC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1271193 Ki 0.35 nM
CC1CCC(NC(=O)c2cc3cc(-c4ccco4)cnc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL3353454 Ki 0.35 nM
CCCCCn1cc(C(=O)C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccco3)ccc21 CHEMBL2087099 Ki 0.37 nM
CCCCCn1c2c(c(O)c(C(=O)NC34CC5CC(CC(C5)C3)C4)c1=O)CCCC2 CHEMBL3780075 Kieq 0.37 nM
O=S(=O)(c1cc2ccccc2n1S(=O)(=O)c1ccccc1F)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL1270885 Ki 0.38 nM
CC(C)(CCCCCCC#N)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL5091754 EC50 0.38 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C3CCCC3)cc1OC2(C)C CHEMBL252947 Ki 0.39 nM
CC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC1 CHEMBL596387 Ki 0.39 nM
CCCCCn1cc2c(=O)n(CC34CC5CC(CC(C5)C3)C4)nc-2c2ccccc21 CHEMBL3421699 Ki 0.39 nM
CC1(C)Oc2cc(C3(CCCCCCCN=C=S)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5074603 EC50 0.39 nM
CSCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL569301 pKi 0.3981 nM
C[C@H]1CN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)CCN1C CHEMBL1209710 pKi 0.3981 nM
O=C(c1cn2c3c(cccc13)OC[C@H]2C1CCCCC1)N1CCN2CCCC[C@H]2C1 CHEMBL1287847 pKi 0.3981 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(F)C4)n3)cc2)C1=O CHEMBL1835215 pEC50 0.3981 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3cccc(CN4CCCC(F)C4)n3)cc2)C1=O CHEMBL1835214 pEC50 0.3981 nM
COc1ccc(S(=O)(=O)c2cc(OC)ccc2S(=O)(=O)c2ccc([C@H](C)NS(C)(=O)=O)cc2)cc1 CHEMBL180465 Ki 0.4 nM
C[C@H](NS(C)(=O)=O)c1ccc(Cc2ccc(OC(F)(F)F)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL381669 Ki 0.4 nM
CC(C)c1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCCC1 CHEMBL404539 EC50 0.4 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccco3)ccc2n1CC1CCOCC1 CHEMBL260666 EC50 0.4 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3c(Cl)cccc3Cl)ccc2n1CC1CCOCC1 CHEMBL265449 EC50 0.4 nM
CCC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2cc3cc(F)ccc3n2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1271093 Ki 0.4 nM
O=S(=O)(c1cc2ccccc2n1S(=O)(=O)c1ccccn1)N1CCC2(CC1)C[C@@H]2NS(=O)(=O)C(F)(F)F CHEMBL1270987 Ki 0.4 nM
CC(NS(=O)(=O)C(F)(F)F)C1CCN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1270886 Ki 0.4 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(-c4ccccc4)ccc23)C1(C)C CHEMBL411244 Ki 0.4 nM
CCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152811 Ki 0.4 nM
CC(C)(CN1CCOCC1)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354960 EC50 0.4 nM
CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)cc1C(=O)/N=c1/sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686304 Ki 0.4 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)C(C)(C)C CHEMBL3650130 Ki 0.4 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2NNC(=O)C(C)(C)C)cc(C(C)(C)C)n1C CHEMBL3650134 Ki 0.4 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(Cl)c(C(C)(C)O)c2)n1 CHEMBL3099056 IC50 0.4 nM
CCC(CC)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CCOCC2)n1)C(=O)OC CHEMBL3929309 EC50 0.4 nM
COC(=O)[C@H](CC(C)C)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3934832 EC50 0.4 nM
CNC(=O)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(C)(C)C CHEMBL3908466 EC50 0.4 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N\OCCCC#N)cc1OC2(C)C CHEMBL4239190 Ki 0.4 nM
CCCCCn1cc(-c2nc(C34CC5CC(CC(C5)C3)C4)no2)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL4756661 Ki 0.4 nM
CC1(C)Oc2cc(C3(CCCCCCCC#N)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5080279 Ki 0.4 nM
Cc1s/c(=N\C(=O)C2C(C)(C)C2(C)C)n(CCCC[18F])c1C CHEMBL5181335 Ki 0.4 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2cccc(C(F)(F)F)c2Cl)n1CC1CC1 CHEMBL401132 IC50 0.41 nM
CCCCCn1c(C)c(C(=O)c2ccc(CC)c3ccccc23)c2ccccc21 CHEMBL564622 pKi 0.4198 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C(C)(C)C)ccc2n1CC1CC1 CHEMBL1800655 EC50 0.43 nM
CCCCCOc1ccc(C(=O)NCCc2ccc(O)cc2)cc1OCCCCC CHEMBL3410811 pKi 0.4395 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NC1CC1 CHEMBL4169198 EC50 0.46 nM
CCCCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL306529 Log Ki 0.47 nM
Cn1c(C2(C)CC2)c/c(=N\C(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)n1C[C@H]1CCCO1 CHEMBL3234698 EC50 0.47 nM
CN1CCCCC1Cn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL571330 pKi 0.4786 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(O)cc3)c(O)nc12 CHEMBL204387 pKi 0.4797 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL411626 Log Ki 0.4898 nM
CCCCCn1c(C)c(C(=O)c2cccc3ccc(C)cc23)c2ccccc21 CHEMBL564066 pKi 0.4898 nM
Cc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(C)(=O)=O)cc2)c(S(=O)(=O)c2ccccc2F)c1 CHEMBL371575 Ki 0.5 nM
CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(CC1CC1)C2 CHEMBL250809 EC50 0.5 nM
CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(=O)(=O)C(C)C)CN(C3CCCC3)C2)CC1 CHEMBL401480 EC50 0.5 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2ccccc2C(F)(F)F)n1CC1CC1 CHEMBL247830 IC50 0.5 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3cccc(C#N)c3)ccc2n1CC1CCOCC1 CHEMBL265694 EC50 0.5 nM
CC(C)(C)c1nc2cc(S(=O)(=O)Cc3ccc(C#N)cc3)ccc2n1CC1CCCCC1 CHEMBL254971 EC50 0.5 nM
O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1cnc2ccc(Cl)cc2c1 CHEMBL526345 EC50 0.5 nM
C[C@@H]1CN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)CC[C@H]1CNS(=O)(=O)C(F)(F)F CHEMBL1269867 Ki 0.5 nM
COCCCOc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL1950830 EC50 0.5 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2ccc(OC)cc2)cc1 CHEMBL2326297 pKi 0.5 nM
CC(C)(C)Cn1nc(C(=O)NC(C)(C)c2ccccc2)c2c1[C@@H]1C[C@@H]1C2 CHEMBL3354937 EC50 0.5 nM
CC(C)(C)c1cn(CC2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2ON=C2CCCC2)s1 CHEMBL3686332 Ki 0.5 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@@H]2CCCO2)s1 CHEMBL3686293 Ki 0.5 nM
CC(CC(N)=O)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C1CC1 CHEMBL3981993 EC50 0.5 nM
C[C@H](Oc1cc(C(=O)NC(C)(CC(N)=O)C2CC2)ncc1C1CC1)C(F)(F)F CHEMBL3950162 EC50 0.5 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(F)(F)C4)n3)cc2)C1=O CHEMBL1835218 pEC50 0.5012 nM
COc1ccc2c(C(=O)C3C(C)(C)C3(C)C)cn(CC3CCOCC3)c2c1 CHEMBL269851 Ki 0.51 nM
CC(C)(C)c1ccc2oc(N3CCCN(c4ncc(C(F)(F)F)cc4Cl)CC3)nc2c1 CHEMBL1800742 EC50 0.51 nM
CCc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL1909860 Ki 0.51 nM
CCCCCCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL338484 Ki 0.52 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)SCCS1 CHEMBL476325 Ki 0.52 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC2CCCCC2)cc1 CHEMBL470965 EC50 0.52 nM
CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C CHEMBL262865 EC50 0.52 nM
O=C(c1ccc2ncccc2c1)N1CC[C@@](O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765259 IC50 0.53 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(O)c2cc(C(C)C)ccc21 CHEMBL3780521 Kieq 0.53 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(Br)c3)cc1OC2(C)C CHEMBL487464 Ki 0.54 nM
O=C(c1csc(-c2ccncc2)n1)N1CCC(O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765092 IC50 0.55 nM
CC1(C)CCc2sc(NC(=O)c3ccccc3Cl)c(C(=O)NCC3CC3)c21 CHEMBL2205578 EC50 0.55 nM
CCOc1ccc(Cc2nc3cc(N(C)S(=O)(=O)c4cccs4)ccc3n2CC2CCCCC2)nc1 CHEMBL1950329 Ki 0.56 nM
O=S(=O)(c1ccc2c(c1)C1C3CCC(C3)C1C(c1ccccc1)N2)N1CCOCC1 CHEMBL3234709 EC50 0.56 nM
CC1CCC(NC(=O)c2cc3cccnc3n(CCCCCF)c2=O)CC1 CHEMBL3353437 Ki 0.56 nM
C=C1CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCCC)cc1OC2(C)C CHEMBL57802 Ki 0.58 nM
COc1ccc(S(=O)(=O)c2cc(OC)ccc2Cc2ccc([C@H](C)NS(C)(=O)=O)cc2)cc1 CHEMBL199048 Ki 0.6 nM
COc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(C)(=O)=O)cc2)c(S(=O)(=O)c2ccccc2)c1 CHEMBL197955 Ki 0.6 nM
CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(C)(=O)=O)CN(C3CCCC3)C2)CC1 CHEMBL249024 EC50 0.6 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccc(C#N)cc3)ccc2n1CC1CCOCC1 CHEMBL408676 EC50 0.6 nM
O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1cnc2ncc(Cl)cc2c1 CHEMBL499050 EC50 0.6 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4Cl)no3)ccc21 CHEMBL527095 EC50 0.6 nM
CCCCCn1c(C)c(C(=O)c2ccc(CCC)c3ccccc23)c2ccccc21 CHEMBL564901 Ki 0.6 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(OC)c21 CHEMBL1814458 Ki 0.6 nM
CN(CCO)C(=O)C(C)(C)NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2018657 Ki 0.6 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCCOCCO CHEMBL2018660 Ki 0.6 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1ONC(C)C CHEMBL3650083 Ki 0.6 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1ONC(=O)C(C)(C)C CHEMBL3650107 Ki 0.6 nM
CNC(=O)[C@@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(C)(C)C CHEMBL4108496 EC50 0.6 nM
CCN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C CHEMBL3910469 EC50 0.6 nM
CC1(C)CCCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3933319 EC50 0.6 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CC3)cn2)no1 CHEMBL3975486 EC50 0.6 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CCC3)cn2)no1 CHEMBL3909299 EC50 0.6 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(C3(F)COC3)cn2)C2CC2)no1 CHEMBL3933315 EC50 0.6 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OC(C)CF)c(C3CC3)cn2)no1 CHEMBL3949331 EC50 0.6 nM
CC(CF)Oc1cc(C(=O)NC(C)(CC(N)=O)C2CC2)ncc1C1CC1 CHEMBL3953854 EC50 0.6 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCCCBr)cc1OC2(C)C CHEMBL4094603 Ki 0.6 nM
CC1(C)Oc2cc(C3(CCCCCCCC#N)CCCC3)cc(O)c2[C@@H]2C[C@H](CN=C=S)CC[C@H]21 CHEMBL5087407 Ki 0.6 nM
[2H]C([2H])([18F])C([2H])([2H])C([2H])([2H])OC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(OC)C2)c(OC[C@H]2C[C@@H]2CO)n1 CHEMBL5205138 Ki 0.6 nM
CC(C)(C)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1[C@H]1CC[C@@H]2C1 CHEMBL3234681 EC50 0.61 nM
COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)c(C)n1CC1CC1 CHEMBL398713 EC50 0.62 nM
O=C(c1cccc2[nH]ccc12)N1CC[C@](O)(c2ccccc2)[C@H]2CCCC[C@H]21 CHEMBL1765246 IC50 0.62 nM
CCCCCn1cc2c(=O)n(CC3CCCCC3)nc-2c2ccccc21 CHEMBL3421697 Ki 0.62 nM
CCCCCn1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(C)c1-c1ccccc1 CHEMBL5273987 Ki 0.63 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCC(C)C)cc1 CHEMBL471980 EC50 0.63 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccccc3)c(=O)[nH]c12 CHEMBL381314 Log IC50 0.631 nM
C[C@@H]1C=C[C@H](C)N1c1ccc(-c2cccc(Cl)c2Cl)nn1 CHEMBL594530 pEC50 0.631 nM
CCCCCC1=NN(C(=O)N[C@H]2C[C@H]3CC[C@]2(C)C3(C)C)CC1c1ccccc1 CHEMBL1223588 pA2 0.631 nM
COCCn1c(C)c(C)s/c1=N\C(=O)C1C(C)(C)C1(C)C CHEMBL1668519 Ki 0.64 nM
Cc1s/c(=N\C(=O)C2C(C)(C)C2(C)C)n(CCO[11CH3])c1C CHEMBL1254015 Ki 0.64 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(Br)ccc23)C1(C)C CHEMBL271838 Log Ki 0.6457 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C3CCCCC3)cc1OC2(C)C CHEMBL325389 Ki 0.65 nM
COc1ccc2c(c1)c(CCN1CCOCC1)c(C)n2C(=O)c1cccc(Cl)c1Cl CHEMBL73711 EC50 0.65 nM
COc1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)N2CCC3(CC2)CC3NS(=O)(=O)C(F)(F)F)cc1 CHEMBL595705 Ki 0.65 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL5178491 Ki 0.65 nM
COc1ccc(-c2nnc(NC(=O)C(C)(C)S(=O)(=O)C3CCOCC3)[nH]2)cc1 CHEMBL3234703 EC50 0.66 nM
CCc1ccc(C(C)(C)c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)cc1 CHEMBL471297 Ki 0.67 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCN2c2ccc(C(F)(F)F)cn2)no1 CHEMBL3235058 EC50 0.67 nM
CC1CCC(NC(=O)c2cc3cc(-c4ccco4)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353448 Ki 0.67 nM
CC1CCC(NC(=O)c2cc3cc(-c4ccc(F)cc4)cnc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL3353453 Ki 0.68 nM
CCCCCn1cc(C(=O)c2ccc(CC)c3ccccc23)c2ccccc21 CHEMBL549603 pKi 0.6902 nM
COc1cc2c(cc1O)c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1 CHEMBL270125 Log Ki 0.6918 nM
CN(c1ccc2c(c1)nc(Cc1ccc3c(c1)CCO3)n2CC1CCCCC1)S(=O)(=O)c1ccccc1 CHEMBL523727 Activity 0.7 nM
O=C(N[C@@H]1CCCc2ccccc21)n1c(=O)n(CCN2CCOCC2)c2ccccc21 CHEMBL523708 EC50 0.7 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC2CCCC2)cc1 CHEMBL471129 EC50 0.7 nM
O=C(NC1CCCCCC1)c1cc2cccnc2n(Cc2ccc(F)cc2)c1=O CHEMBL467896 Ki 0.7 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cccnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL466047 Ki 0.7 nM
C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL245742 Ki 0.7 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL1215942 Ki 0.7 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-n3cccc3)ccc21 CHEMBL1215955 Ki 0.7 nM
C[C@@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL1270387 Ki 0.7 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1Cl CHEMBL1641956 Ki 0.7 nM
O=C(c1cccc(F)c1C(F)(F)F)c1nc(CN2CCOCC2)c2ccccn12 CHEMBL1760931 IC50 0.7 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(C)c21 CHEMBL1668518 Ki 0.7 nM
Cc1sc(NC(=O)N2CCCN(C(=O)C3CCC(F)(F)CC3)CC2)nc1C(C)(C)C CHEMBL3234705 EC50 0.7 nM
O=C(NC1(CO)CCCC1)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354955 EC50 0.7 nM
CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21)c1ccccn1 CHEMBL3354949 EC50 0.7 nM
CC(C)(NC(=O)c1nn(CC2CCOCC2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354938 EC50 0.7 nM
CCOCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(OC)c21 CHEMBL3409318 Ki 0.7 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@@H]2CCCCN2)s1 CHEMBL3686334 Ki 0.7 nM
CN1CCCC[C@H]1COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686335 Ki 0.7 nM
CCCCn1nc(C(C)(C)C)s/c1=N/C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)OC CHEMBL3650129 Ki 0.7 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2NNC(=O)c2ccncc2)cc(C(C)(C)C)n1C CHEMBL3650136 Ki 0.7 nM
CC(C)C[C@H](NC(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1)C(N)=O CHEMBL3950265 EC50 0.7 nM
COC(=O)C(C)(NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1)C1CC1 CHEMBL3918487 EC50 0.7 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC3CC3)c(C3CC3)cn2)C2CC2)no1 CHEMBL3945608 EC50 0.7 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C3(C(=O)OCCCCBr)CCC3)cc1OC2(C)C CHEMBL4085404 Ki 0.7 nM
CCCSC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL4068675 Ki 0.7 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCBr)cc1OC2(C)C CHEMBL4102348 Ki 0.7 nM
CCOCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(O[11CH3])c21 CHEMBL3409321 Ki 0.7 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCN3CCOCC3)cc1OC2(C)C CHEMBL4246445 Ki 0.7 nM
O=C(NC12CC3CC(CC1C3)C2)c1nn(-c2ccc(F)cc2F)c2c1CC1CCC2O1 CHEMBL4872695 EC50 0.7 nM
CC1(C)C(C(=O)c2cn(CCCCCO)c3ccccc23)C1(C)C CHEMBL571131 pKi 0.7079 nM
CC1(C)Cc2ccc(C#N)cc2[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL3234672 Ki 0.71 nM
CCCCCn1c(C)c(C(=O)c2ccc(C)c3ccccc23)c2ccccc21 CHEMBL561090 pKi 0.7295 nM
CC(C)Cn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1OCCO CHEMBL3647318 Ki 0.73 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccncc3)c(=O)n(C)c12 CHEMBL3407534 pKi 0.7499 nM
CC1CCC(NC(=O)c2c(O)c3cccnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3422790 Ki 0.75 nM
CC1CCC(NC(=O)c2cc3ccccc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3422784 Ki 0.75 nM
CC(C)(C)c1cc(NC(=O)C(C)(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)no1 CHEMBL3400937 EC50 0.77 nM
CC(C)(CCCCCCN=[N+]=[N-])c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL5081770 EC50 0.77 nM
CC(C)(O)c1cc(-c2nc(NCCc3ccc(F)cc3)nc(OCF)n2)ccc1Cl CHEMBL3099054 EC50 0.78 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL109393 EC50 0.79 nM
Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cccc(C(F)(F)F)c2F)n1CC1CCCC1 CHEMBL263913 EC50 0.79 nM
CCc1ccc(/C=C2\C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 CHEMBL4483714 Ki 0.79 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCCc3ccccc3)c(=O)[nH]c12 CHEMBL204433 Log IC50 0.7943 nM
Cc1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(C)n1-c1ccccc1 CHEMBL599071 pEC50 0.7943 nM
COc1cccc2c(C(=O)N3C[C@@H](C)N(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 CHEMBL1209708 pKi 0.7943 nM
CCCN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C1=O CHEMBL1835130 pEC50 0.7943 nM
COc1cccc2c(C(=O)N3C[C@@H](C)N(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 CHEMBL3347370 pKi 0.7943 nM
CCCCOc1c(OC)ccc2cc(C(=O)NCC(F)c3ccccc3)c(=O)[nH]c12 CHEMBL1822932 pKi 0.7998 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1ccccc1C(C)C CHEMBL443842 Ki 0.8 nM
CCCN1Cc2c(n(S(=O)(=O)CC)c3ccc(C(=O)N4CCC(C)CC4)cc23)C1 CHEMBL400399 EC50 0.8 nM
CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)C2 CHEMBL249025 EC50 0.8 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCCCC1 CHEMBL256534 EC50 0.8 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccnc(F)c3)ccc2n1CC1CCOCC1 CHEMBL261347 EC50 0.8 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3nccs3)ccc2n1CC1CCOCC1 CHEMBL412122 EC50 0.8 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc(F)cc21 CHEMBL525528 Ki 0.8 nM
O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1nnc(N2CCCCC2)s1 CHEMBL502263 EC50 0.8 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(F)c2ccccc12 CHEMBL482355 Ki 0.8 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL382728 Ki 0.8 nM
COc1ccc2c(c1)cc(S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1)n2S(=O)(=O)c1ccccc1F CHEMBL1270579 Ki 0.8 nM
COCCCNc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL1950829 EC50 0.8 nM
CCCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152802 Ki 0.8 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2c2ccc(Cl)cc2)no1 CHEMBL3354527 EC50 0.8 nM
CCOCCn1cc(C(=O)NC23CC4CC(CC(O)(C4)C2)C3)c(=O)c2cccc(OC)c21 CHEMBL3409320 Ki 0.8 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)c1ccncc1 CHEMBL3650128 Ki 0.8 nM
CC(C)C[C@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(N)=O CHEMBL3940084 EC50 0.8 nM
CN(C(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1)C(C)(C)C CHEMBL3952053 EC50 0.8 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCCBr)cc1OC2(C)C CHEMBL4074070 Ki 0.8 nM
CCCCOC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL4475022 Ki 0.8 nM
CC1(C)Oc2cc(C3(CCCCCCN=[N+]=[N-])CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5077315 Ki 0.8 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(O)c2ccc(F)cc21 CHEMBL3780852 Ki 0.8 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(COC(=O)CN2CCOCC2)c1 CHEMBL233184 Ki 0.81 nM
O=C(NC1CCCCCC1)c1cn2c3c(cccc3c1=O)OCC2c1ccccc1 CHEMBL2163950 Ki 0.81 nM
CCCCn1cc(C(=O)c2cccc3ccccc23)c2cccc(OC)c21 CHEMBL2380420 Ki 0.81 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)oc(=O)c1ccc(O)cc12 CHEMBL429797 Ki 0.82 nM
O=C(c1ccc2ccccc2n1)N1CC[C@](O)(c2ccccc2)[C@H]2CCCC[C@H]21 CHEMBL1765161 IC50 0.82 nM
CCCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1OCC(C)(C)O CHEMBL3647331 Ki 0.82 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(CC)cc12 CHEMBL2381809 Ki 0.84 nM
CC(C)OCCn1/c(=N/C(=O)c2cccc(C(F)(F)F)c2F)cc(C(C)(C)C)n1C CHEMBL440407 EC50 0.85 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CC1 CHEMBL19847 Log Ki 0.8511 nM
CCS(=O)(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2CC1CCC(F)(F)CC1 CHEMBL4550236 Ki 0.87 nM
CC(C)(C)c1nc2cc(NS(C)(=O)=O)ccc2n1CC1CCC(F)(F)CC1 CHEMBL4454159 pKi 0.871 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(OCc4ccccc4)ccc23)C1(C)C CHEMBL270546 Ki 0.88 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(C)cc3)cc1OC2(C)C CHEMBL512511 Ki 0.88 nM
COc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(C)(=O)=O)cc2)c(S(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL370824 Ki 0.9 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(C(F)(F)F)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL198246 Ki 0.9 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc2nonc12 CHEMBL232538 Ki 0.9 nM
CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(C)C)C2 CHEMBL250609 EC50 0.9 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc(S(=O)(=O)c3ccccc3)cc21 CHEMBL507019 Ki 0.9 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(F)c3)cc1OC2(C)C CHEMBL512531 Ki 0.9 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cccc2ccccc12 CHEMBL516406 Ki 0.9 nM
COc1ccccc1/N=C1\OCC2(CCCCC2)CN1C(=S)SC CHEMBL469895 Ki 0.9 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(Cl)c2ccccc12 CHEMBL482356 Ki 0.9 nM
CC1CCC(NC(=O)c2cc3cccnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL466651 Ki 0.9 nM
O=S(=O)(c1ccccn1)c1ccc(OC(F)(F)F)cc1S(=O)(=O)N1CCC2(CC1)CC2NS(=O)(=O)C(F)(F)F CHEMBL595223 Ki 0.9 nM
O=S(=O)(c1cc2ccccc2n1S(=O)(=O)c1ccccn1)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL1270784 Ki 0.9 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1Cl CHEMBL1909856 Ki 0.9 nM
CC(C)CCn1c2c(cc(C(=O)NCc3ccccc3)c1=O)CCCCCC2 CHEMBL2387178 Ki 0.9 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2CC2CC2)no1 CHEMBL3354531 EC50 0.9 nM
CC(C)(CO)NC(=O)c1nn(-c2cc(F)ccc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354971 EC50 0.9 nM
CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354942 EC50 0.9 nM
CC(C)(C)C(=O)COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686323 Ki 0.9 nM
Cc1nc([C@@](C)(NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)C2CC2)no1 CHEMBL3937198 EC50 0.9 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCCC#N)cc1OC2(C)C CHEMBL4062745 Ki 0.9 nM
CCCCCN1C(=O)C(C(=O)NC23CC4CC(CC(C4)C2)C3)=C(O)C2C1C=NN2C CHEMBL4637535 Ki 0.9 nM
COc1cccc2c(=O)c(C(=O)NC34CC5CC(CC(C5)C3)C4)cn(CCOCCC[18F])c12 CHEMBL5182619 Ki 0.9 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccccc3)cc1OC2(C)C CHEMBL119592 Ki 0.91 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(C#N)c3)cc1OC2(C)C CHEMBL471366 Ki 0.91 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C(C)(C)C(N)=O)ccc2n1CC1CC1 CHEMBL3234673 EC50 0.91 nM
CCCCn1nc(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 CHEMBL5169682 pKi 0.912 nM
CC1=CCC2C(C1)c1c(O)cc(CCCCCF)cc1OC2(C)C CHEMBL75330 Log Ki 0.94 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cc(-c4cccs4)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353446 Ki 0.96 nM
CC1(C)Oc2cc(C3(CCCCCCC#N)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5071417 EC50 0.96 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(O)c(OC)c3)c(=O)[nH]c12 CHEMBL3410816 Ki 0.97 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(O)c2ccccc21 CHEMBL3780166 Kieq 0.97 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)C[C@@H]21 CHEMBL5187099 Ki 0.97 nM
CC(=O)CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL584105 Ki 0.99 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)CC3CCN(C(N)=O)CC3)ccc2n1CC1CC1 CHEMBL3357379 EC50 0.99 nM
COc1cccc2c3c(=O)n([C@@H]4C(C)(C)[C@@H]5CC[C@@]4(C)C5)ccc3n(CCN3CCOCC3)c12 CHEMBL527031 Ki 1.0 nM
CCCCCCC(C)(C)c1ccc2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL331838 Ki 1.0 nM
C[C@H](NS(C)(=O)=O)c1ccc(Cc2ccc(C(F)(F)F)cc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL199102 Ki 1.0 nM
CCCCCCC(C)(C)c1ccc(-c2ccccc2OC)c(O)c1 CHEMBL234678 Ki 1.0 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc(C)c1C CHEMBL232132 Ki 1.0 nM
COc1cccc(/N=C2\SCC3(CCCCC3)CN2C(=S)SC)c1 CHEMBL231932 Ki 1.0 nM
CSC(=S)N1CC2(CCCC2)CS/C1=N\c1ccccc1C(C)C CHEMBL232929 Ki 1.0 nM
Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCSCC1 CHEMBL401664 EC50 1.0 nM
Cc1ccc(C(=O)Nc2nccc3ccccc23)cc1S(=O)(=O)N1CCCCC1 CHEMBL439248 EC50 1.0 nM
Cc1ccc(C(=O)N2CC[C@@H]3CCCC[C@H]3C2)cc1S(=O)(=O)N1CCCCC1 CHEMBL427889 EC50 1.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc4c(cc23)OCO4)C1(C)C CHEMBL272868 Ki 1.0 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CCCC(F)(F)F)ccc2n1CC1CCOCC1 CHEMBL401610 EC50 1.0 nM
CC(C)CCn1c(=O)n(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 CHEMBL527071 Ki 1.0 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC2CCOCC2)cc1 CHEMBL471374 EC50 1.0 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1nc(C(C)(C)C)cs1 CHEMBL511790 Ki 1.0 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cc(C(C)(C)C)no1 CHEMBL481508 Ki 1.0 nM
CCC(CC)(CC)c1cc(/N=C2\OCC3(CCCCC3)CN2C(=S)SC)on1 CHEMBL519288 Ki 1.0 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cccc2c1CCCC2 CHEMBL480578 Ki 1.0 nM
CC1(C)C(C(=O)c2cn(CC3OCCO3)c3ccccc23)C1(C)C CHEMBL570454 Ki 1.0 nM
O=S(=O)(c1cc2ccccc2n1S(=O)(=O)c1ccccc1F)N1CCC2(CC1)C[C@@H]2NS(=O)(=O)C(F)(F)F CHEMBL1270389 Ki 1.0 nM
CC(C)(C)c1ccc2oc(N3CCCN(C(=O)C4CCOCC4)CC3)nc2c1 CHEMBL1800751 EC50 1.0 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc([N+](=O)[O-])c21 CHEMBL1814459 Ki 1.0 nM
CCCNC(=O)c1c(NC(=O)C2C(C)(C)C2(C)C)sc2c1CCOC2 CHEMBL2010905 pIC50 1.0 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCCCO CHEMBL2018658 Ki 1.0 nM
O=C(NC1(C(=O)O)CCCCCCC1)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2019078 IC50 1.0 nM
COc1ccc(-c2cc(C(=O)NC3CCCCCC3)c(=O)n(Cc3ccc(F)cc3)c2)cc1 CHEMBL3114181 Ki 1.0 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OCc2ccccn2)s1 CHEMBL3234699 EC50 1.0 nM
O=C(NC1CCCC1)c1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)CCS2 CHEMBL3234688 EC50 1.0 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1ONC(C)=O CHEMBL3650093 Ki 1.0 nM
CCCCn1nc(C(C)(C)C)s/c1=N/C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)OC(C)(C)C CHEMBL3650118 Ki 1.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(F)c3cccnc23)n1 CHEMBL3669094 IC50 1.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(OC)c(C(C)(C)O)c2)n1 CHEMBL3669058 IC50 1.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(Cl)c(OCC(N)=O)c2)n1 CHEMBL3669116 IC50 1.0 nM
C[C@H](Oc1cc(C(=O)NC(c2noc(N)n2)C(C)(C)C)ncc1C1CC1)C(F)(F)F CHEMBL3984692 EC50 1.0 nM
CNC(=O)CC(C)(NC(=O)c1cc(O[C@@H](C)C(F)(F)F)c(C2CC2)cn1)C1CC1 CHEMBL3976062 EC50 1.0 nM
CCCCC(=O)OCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL4092136 Ki 1.0 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCCC(F)(F)F)cc1OC2(C)C CHEMBL4240671 EC50 1.0 nM
CCCc1ccc(/C=C2\C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 CHEMBL4443660 Ki 1.0 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CC1(Br)Br CHEMBL118631 Log Ki 1.023 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3c(CC4CCOCC4)c4c(cc23)OCO4)C1(C)C CHEMBL1836186 pKi 1.023 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C3(C4CCCCC4)SCCS3)cc1OC2(C)C CHEMBL117033 Ki 1.05 nM
CC(C)(c1ccccc1)c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1 CHEMBL525067 Ki 1.07 nM
CCCCCn1cc(C(=O)c2ccc(CCC)c3ccccc23)c2ccccc21 CHEMBL564302 pKi 1.099 nM
CCCCCSc1cc(/C=C/C(=O)NCCc2ccc(O)cc2)ccc1OC CHEMBL3410820 pKi 1.099 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc2c1CCCN2C CHEMBL233139 Ki 1.1 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1ccccc1C(F)(F)F CHEMBL232131 Ki 1.1 nM
COc1ccccc1/N=C1\SCC2(CCCCC2)CN1C(=S)SC CHEMBL231721 Ki 1.1 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCOc3ccc(C#N)cc3)cc1OC2(C)C CHEMBL136120 Ki 1.1 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCC#N)cc1OC2(C)C CHEMBL336670 Ki 1.1 nM
CCOCCn1/c(=N/C(=O)c2cccc(C(F)(F)F)c2F)cc(C(C)(C)C)n1C CHEMBL410243 EC50 1.1 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2Cc2ccccc2)cc1 CHEMBL471992 EC50 1.1 nM
CCCCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCOCC2)c1 CHEMBL595268 Ki 1.1 nM
CS(=O)(=O)NC1CC12CCN(S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)c1ccccc1F)CC2 CHEMBL596133 Ki 1.1 nM
COCCCc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL1950833 EC50 1.1 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(O)CC1 CHEMBL2018664 Ki 1.1 nM
COCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152816 Ki 1.1 nM
CCCCCn1cc(C(=O)c2ccc(Br)c3ccccc23)c2ccccc21 CHEMBL2206834 Ki 1.1 nM
Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 CHEMBL111 Ki 1.1 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC2CCOCC2)no1 CHEMBL3353869 EC50 1.1 nM
CC1(C)[C@H]2CC[C@](C)(C2)[C@H]1NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354961 EC50 1.1 nM
C[C@@H](O)COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686331 Ki 1.1 nM
CCCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)c1ccncc1 CHEMBL3647335 Ki 1.1 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)c1cccnc1 CHEMBL3650133 Ki 1.1 nM
CC(C)C[C@H](NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(N)=O CHEMBL3930575 EC50 1.1 nM
COC(=O)[C@@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(C)(C)C CHEMBL4115612 EC50 1.1 nM
Cc1nc([C@H](CC2CC2)NC(=O)c2ccc(C3CC3)c(Cc3ccc(F)cc3)n2)no1 CHEMBL3914978 EC50 1.1 nM
Cc1c(Br)cn(Cc2ccc(F)cc2)c(=O)c1C(=O)NC1CCCCCC1 CHEMBL4164954 EC50 1.1 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2c(C)csc21 CHEMBL2316284 Ki 1.12 nM
C[C@H]1CC[C@H](NC(=O)c2cc3cc(Br)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353440 Ki 1.12 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(C)c3)cc1OC2(C)C CHEMBL471295 Ki 1.13 nM
CCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL306764 Log Ki 1.14 nM
CCCCCCC(C)(C)c1cc(OC)cc(OCCCCCCCC(=O)NC2CC2)c1 CHEMBL4647981 EC50 1.16 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2cccnc2n(CCCCF)c1=O CHEMBL5198892 IC50 1.17 nM
CCCCCn1cc(C(=O)c2ccc(C)c3ccccc23)c2ccccc21 CHEMBL557004 pKi 1.199 nM
CCc1ccc(/N=C2\SCC3(CCCCC3)CN2C(=S)SC)cc1 CHEMBL392842 Ki 1.2 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccncc3)ccc2n1CC1CCOCC1 CHEMBL259113 EC50 1.2 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccccc3)ccc2n1CC1CCCCC1 CHEMBL255519 EC50 1.2 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCOCC1 CHEMBL429134 EC50 1.2 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2ccc(Br)cc2)n1CC1CC1 CHEMBL1668505 Ki 1.2 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C(C)(C)CO)ccc2n1CC1CC1 CHEMBL1800166 EC50 1.2 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccnc(OCCCO)c3)ccc2n1CC1CCOCC1 CHEMBL1950832 EC50 1.2 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCCCCCO CHEMBL2018659 Ki 1.2 nM
O=C(N[C@H](C(=O)O)c1ccccc1)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2023045 Ki 1.2 nM
O=C(NC1CCCCCC1)c1cc(-c2ccccc2)cn(Cc2ccc(F)cc2)c1=O CHEMBL3114182 Ki 1.2 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C3CN(C(N)=O)C3)ccc2n1CC1CC1 CHEMBL3357367 EC50 1.2 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCC(=O)N2c2ccc(C#N)cn2)on1 CHEMBL3353886 EC50 1.2 nM
O=C(NC1(CO)CCC1)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354954 EC50 1.2 nM
CC(=O)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686326 Ki 1.2 nM
COc1nc(NCCc2ccc(OC(F)F)cc2)nc(-c2ccc(Cl)c(C(C)(C)O)c2)n1 CHEMBL3669056 IC50 1.2 nM
CC(C)C[C@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(N)=O CHEMBL3929434 EC50 1.2 nM
Cc1nc([C@H](CC(C)C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1 CHEMBL3915279 EC50 1.2 nM
CC1(C)C[C@@H](C(N)=O)N(C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C1 CHEMBL3898677 EC50 1.2 nM
CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(=O)N1CCC1 CHEMBL3978125 EC50 1.2 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(CC(=O)OCCCCC#N)cc1OC2(C)C CHEMBL4098489 Ki 1.2 nM
CCCCCn1cc(-c2cn(C34CC5CC(CC(C5)C3)C4)nn2)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL4061179 Ki 1.2 nM
COc1cccc2c(=O)c(C(=O)NC34CC5CC(CC(C5)C3)C4)cn(CCOCC[18F])c12 CHEMBL4070881 Ki 1.2 nM
O=C(NC1(C(F)(F)F)CCC1)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL4161506 EC50 1.2 nM
CC(C)(C)[C@@H](CF)NC(=O)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL4174510 EC50 1.2 nM
CCCCCc1cc(OC)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL4644215 Ki 1.2 nM
CC(C)[C@@H]1COc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163926 Ki 1.24 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL5183968 Ki 1.25 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(OCc4ccccc4)cc23)C1(C)C CHEMBL272876 Log Ki 1.259 nM
C[C@@H]1CC[C@H](C)N1c1ccc(-c2cccc(Cl)c2Cl)nn1 CHEMBL594529 pEC50 1.259 nM
CCCN1C(=O)CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C1=O CHEMBL1835120 pEC50 1.259 nM
CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL3353442 Ki 1.26 nM
CCCCCc1cccc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL4646867 EC50 1.28 nM
COc1ccc(S(=O)(=O)c2cc(OC)ccc2S(=O)(=O)c2ccc(CNS(C)(=O)=O)cc2)cc1 CHEMBL197777 Ki 1.3 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc2nsnc12 CHEMBL232336 Ki 1.3 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C CHEMBL271824 Ki 1.3 nM
Cc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL411296 EC50 1.3 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CC3CC3)ccc2n1CC1CCOCC1 CHEMBL257817 EC50 1.3 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CCC(F)(F)F)ccc2n1CC1CCOCC1 CHEMBL257613 EC50 1.3 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC23CC4CC(CC(C4)C2)C3)cc1 CHEMBL511134 EC50 1.3 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC2CCC2)cc1 CHEMBL472506 EC50 1.3 nM
Cc1c(C(=O)NC2CCCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL576549 Ki 1.3 nM
COCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL572000 Ki 1.3 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(Cl)ccc1Cl CHEMBL1909858 Ki 1.3 nM
COCCOc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL1950831 EC50 1.3 nM
CN(C)CCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152815 Ki 1.3 nM
CCCCCn1cc(C(=O)c2ccc(I)c3ccccc23)c2ccccc21 CHEMBL2206838 Ki 1.3 nM
CC(C)(NC(=O)c1nn(CCC2CCOCC2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354939 EC50 1.3 nM
CC(C)(O)CCOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686339 Ki 1.3 nM
CN1CCC[C@H]1COc1ccc(C(F)(F)F)cc1C(=S)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686311 Ki 1.3 nM
CNC(=O)[C@H](CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3982424 EC50 1.3 nM
COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3963221 EC50 1.3 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCn3ccnc3)cc1OC2(C)C CHEMBL4098428 Ki 1.3 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCCC#N)cc1OC2(C)C CHEMBL4249273 Ki 1.3 nM
CC1(C)Oc2cc(C3(CCCCCCN=C=S)CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5092703 Ki 1.3 nM
CCCCn1cc(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 CHEMBL5202843 pKi 1.318 nM
CC1(C)Oc2cc(C3(CCCCCBr)CCCC3)cc(O)c2[C@@H]2CC(=O)CC[C@H]21 CHEMBL1259037 Ki 1.32 nM
O=C1/C(=C/c2cn(Cc3ccc(F)cc3)c3ccccc23)N2CCC1CC2 CHEMBL240913 Ki 1.33 nM
COc1ccc(OC)c(N(CC(=O)NCc2ccncc2)S(=O)(=O)c2ccc(C)cc2)c1 CHEMBL522719 Ki 1.35 nM
CC1CCC(NC(=O)c2cc3cccnc3n(CCCCF)c2=O)CC1 CHEMBL3353436 Ki 1.36 nM
CCCCCn1cc(C(=O)c2cccc3c2CC(C)(C)C3)c2ccccc21 CHEMBL4860950 Ki 1.36 nM
CCCCCCC(C)(C)c1ccc([C@H]2C[C@@H](O)CC[C@@H]2CCCO)c(O)c1 CHEMBL2062131 Log Ki 1.37 nM
COC(=O)c1ccc2c(C(=O)C3C(C)(C)C3(C)C)cn(CC3CCOCC3)c2c1 CHEMBL271810 Log Ki 1.38 nM
O=S(=O)(c1ccccc1F)c1occc1S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL1270681 Ki 1.4 nM
O=C(c1ccc2[nH]ccc2c1)N1CC[C@@](O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765261 IC50 1.4 nM
CCCCOc1c(OC)c([N+](=O)[O-])cc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c12 CHEMBL1822933 Ki 1.4 nM
CC(=O)NCCc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL1950835 EC50 1.4 nM
O=C(Nc1sc2c(c1C(=O)N1CCC(F)(F)CC1)CCOC2)c1ccccc1C(F)(F)F CHEMBL2205594 EC50 1.4 nM
CCCCn1c2c(cc(C(=O)NCc3ccccc3)c1=O)CCCCCC2 CHEMBL2387078 IC50 1.4 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCC(=O)N2c2ccc(C(F)(F)F)cc2)on1 CHEMBL3353881 EC50 1.4 nM
O=C(NC1(c2ccccc2)CC1)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354946 EC50 1.4 nM
O=C(Nc1cc(C(F)(F)F)on1)N1CCCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 CHEMBL3400938 EC50 1.4 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@H](C)O)sc2ncccc21 CHEMBL3647333 Ki 1.4 nM
CC(C)(c1ccccc1)c1ccc(-c2cc(Cl)cc(Cl)c2)c(O)c1 CHEMBL3950898 Ki 1.4 nM
CNC(=O)[C@@H](NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1)C(C)(C)C CHEMBL4114962 EC50 1.4 nM
CC(C)C[C@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)N(C)C CHEMBL3901105 EC50 1.4 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)OC CHEMBL3936836 EC50 1.4 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CCCC2)c(OCC2CC2)n1 CHEMBL3894212 EC50 1.4 nM
CCC(CC)(NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(=O)OC CHEMBL3978508 EC50 1.4 nM
Cc1nc(C(C)(NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(N3CC(F)(F)C3)cn2)C2CC2)no1 CHEMBL3950922 EC50 1.4 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCC#N)cc1OC2(C)C CHEMBL4071389 Ki 1.4 nM
[2H]C([2H])([18F])Oc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(Cl)c(C(C)(C)O)c2)n1 CHEMBL3099055 IC50 1.4 nM
CN1N=CC2C1C(O)=C(C(=O)NC13CC4CC(CC(C4)C1)C3)C(=O)N2CCCCF CHEMBL4647226 Ki 1.4 nM
Cc1c(Br)cn(CCCc2cn(CCCCCn3c(C)c(Br)cc(C(=O)NC4CCCCCC4)c3=O)nn2)c(=O)c1NC(=O)C1CCCCCC1 CHEMBL5193398 Ki 1.4 nM
CC1CCC(NC(=O)c2cc3cccnc3n(CCCCCCF)c2=O)CC1 CHEMBL3353438 Ki 1.46 nM
COc1ccc(-c2cnc3c(c2)cc(C(=O)NC2CCC(C)CC2)c(=O)n3CCN2CCOCC2)cc1 CHEMBL3353451 Ki 1.47 nM
CC1=CCC2C(C1)c1c(O)cc(CCCCC(F)(F)F)cc1OC2(C)C CHEMBL74662 Log Ki 1.48 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL5189892 Ki 1.48 nM
CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(=O)(=O)C3CC3)CN(C3CCCC3)C2)CC1 CHEMBL404211 EC50 1.5 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2cc(C(F)(F)F)ccc2F)n1CC1CC1 CHEMBL248385 EC50 1.5 nM
Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCCCC1 CHEMBL402154 EC50 1.5 nM
Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cccc(C(F)(F)F)c2Cl)n1CC1CC1 CHEMBL261031 EC50 1.5 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL465 EC50 1.5 nM
CSC(=O)N1CC2(CCCCC2)CS/C1=N\c1cccc2ccccc12 CHEMBL475772 Ki 1.5 nM
O=S(=O)(c1ccccc1F)c1cc(Cl)ccc1S(=O)(=O)N1C[C@@H]2[C@H](C1)[C@H]2NS(=O)(=O)C(F)(F)F CHEMBL604704 Ki 1.5 nM
C[C@@H]1CN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)CC[C@@H]1CNS(=O)(=O)C(F)(F)F CHEMBL1269973 Ki 1.5 nM
CC(C)CN1CCCC[C@H]1C(=O)Nc1cc(C(C)(C)C)on1 CHEMBL3354532 EC50 1.5 nM
CCCCCn1c(=O)c(C(=O)NC2CCC(C)CC2)cc2ccccc21 CHEMBL3422788 Ki 1.5 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OCCNC(C)=O)sc2ccncc21 CHEMBL3647324 Ki 1.5 nM
Cc1nc([C@](C)(CC2CC2)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1 CHEMBL3941296 EC50 1.5 nM
C[C@H](Oc1cc(C(=O)NC(C(N)=O)C(C)(C)C)ncc1C1CC1)C(F)(F)F CHEMBL3889656 EC50 1.5 nM
CC(CC(N)=O)(NC(=O)c1cc(OCCF)c(C2CC2)cn1)C1CC1 CHEMBL3922649 EC50 1.5 nM
CCOC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL4073011 Ki 1.5 nM
Cc1c(Br)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4753891 Ki 1.5 nM
Cc1nc(OCc2ccc(F)cc2)c(C(=O)NC2CCCCCC2)cc1Br CHEMBL4780771 Ki 1.5 nM
CC1(C)Oc2cc(C3(CCCCCCCN=[N+]=[N-])CCCC3)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL5080450 Ki 1.5 nM
CC1(C)Oc2cc(C3(CCCCCCCN=[N+]=[N-])CCCC3)cc(O)c2[C@@H]2C[C@H](CN=[N+]=[N-])CC[C@H]21 CHEMBL5081699 Ki 1.5 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(Br)cc3)cc1OC2(C)C CHEMBL487463 Ki 1.54 nM
CC(C)C[C@H](NC(=O)c1ccc(N2CCCC2C)c(OCC2CC2)n1)C(N)=O CHEMBL3929481 EC50 1.55 nM
CNC(=O)[C@@H](NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(C)(C)C CHEMBL4112673 EC50 1.575 nM
COc1ccc2c(C(=O)C3C(C)(C)C3(C)C)cn(CCN3CCOCC3)c2c1 CHEMBL409265 Log Ki 1.585 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(F)cc23)C1(C)C CHEMBL410677 Log Ki 1.585 nM
CCc1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(C)n1-c1ccccc1 CHEMBL599882 pEC50 1.585 nM
CCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(N)cc3)c(=O)[nH]c12 CHEMBL2096743 pIC50 1.585 nM
CCN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C1=O CHEMBL1835129 pEC50 1.585 nM
COc1cccc2c(C(=O)N3CCN(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 CHEMBL3347369 pKi 1.585 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C(C)C)n2CC1CCCCC1 CHEMBL404675 EC50 1.6 nM
CC(=O)N(C)Cc1ccc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)cc1 CHEMBL259322 EC50 1.6 nM
CC(C)(C)c1nc2cc(S(=O)(=O)C(F)(F)c3ccc(C#N)cc3)ccc2n1CC1CCCCC1 CHEMBL402816 EC50 1.6 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL498527 Ki 1.6 nM
Cc1c(C(=O)N[C@H](C)C2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL574480 Ki 1.6 nM
O=S(=O)(c1ccccn1)c1ccc(Cl)cc1S(=O)(=O)N1CCC2(CC1)CC2NS(=O)(=O)C(F)(F)F CHEMBL592896 Ki 1.6 nM
CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccn2)CC1 CHEMBL1271194 Ki 1.6 nM
O=C(c1cccc2[nH]ncc12)N1CCC(O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765278 IC50 1.6 nM
CCCCn1c2c(cc(C(=O)NCCc3ccccc3)c1=O)CCCCCC2 CHEMBL2387186 Ki 1.6 nM
CCCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1NNC(=O)c1cccnc1 CHEMBL3647334 Ki 1.6 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1O/N=C1/CCCCCN1 CHEMBL3650126 Ki 1.6 nM
CCC(CC)(NC(=O)c1ccc(N(CC(F)(F)F)CC(F)(F)F)c(OCC2CC2)n1)C(=O)OC CHEMBL3963244 EC50 1.6 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)N1CCC1 CHEMBL3965420 EC50 1.6 nM
C[C@H](Oc1cc(C(=O)NC2(CC(N)=O)CS(=O)(=O)C2)ncc1C1CC1)C(F)(F)F CHEMBL3972174 EC50 1.6 nM
CC1(C)Oc2cc(C3(CCCCCBr)CCC3)cc(O)c2[C@@H]2C[C@H](O)CC[C@H]21 CHEMBL1259091 Ki 1.62 nM
CC1(C)Oc2cc(C3(CCCCCBr)CCC3)cc(O)c2[C@@H]2C[C@@H](O)CC[C@H]21 CHEMBL1259092 Ki 1.63 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1CN1CC(O)C1 CHEMBL3234700 Ki 1.63 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCCc3ccccc3)cc1OC2(C)C CHEMBL4237501 EC50 1.65 nM
COc1cc(C(O)c2ccccc2)cc(OC)c1-c1cc(Cl)cc(Cl)c1 CHEMBL460544 Ki 1.66 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(Cl)cc3)cc1OC2(C)C CHEMBL471988 Ki 1.68 nM
CCCCCCC1(c2ccc(-c3cc(C)cc(C)c3)c(O)c2)CCCCC1 CHEMBL233636 Ki 1.7 nM
CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCCO1)C2 CHEMBL250607 EC50 1.7 nM
CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCCCC4)ccc31)CN(C1CCCC1)C2 CHEMBL250493 EC50 1.7 nM
Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL272203 Ki 1.7 nM
Fc1ccc(-c2noc(CCCNc3cnc4ccc(Cl)cc4c3)n2)c(Cl)c1 CHEMBL499065 EC50 1.7 nM
Cc1ccc(NC(=O)[C@@H]2C(C)(C)[C@@H]3CC[C@@]2(C)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL515090 Ki 1.7 nM
O=S(=O)(c1ccccc1F)c1cc(Cl)ccc1S(=O)(=O)N1CCC2(CC1)CC2NS(=O)(=O)C(F)(F)F CHEMBL596579 Ki 1.7 nM
O=C(Nc1cccc(C(F)(F)F)n1)c1nc(CN2CCC(F)(F)CC2)c2ccccn12 CHEMBL1760933 IC50 1.7 nM
CCc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C CHEMBL1909957 Ki 1.7 nM
CCCCOC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL3104360 Ki 1.7 nM
CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)nn1CC1CCCCO1 CHEMBL3650086 Ki 1.7 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1ON=C1CCCC1 CHEMBL3650127 Ki 1.7 nM
CNC(=O)[C@H](CC(C)(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3912526 EC50 1.7 nM
COC(=O)[C@@H](NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(C)(C)C CHEMBL4107544 EC50 1.7 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)C2CC2)no1 CHEMBL3966304 EC50 1.7 nM
Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CCC3)cn2)no1 CHEMBL3946121 EC50 1.7 nM
CC(CC(N)=O)(NC(=O)c1cc(OCC(F)F)c(C2CC2)cn1)C1CC1 CHEMBL3980218 EC50 1.7 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N\OCCCc3ccccc3)cc1OC2(C)C CHEMBL4245472 EC50 1.7 nM
CCCCc1sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c(C(=O)OC)c1C CHEMBL4462947 Ki 1.72 nM
O=C(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 CHEMBL3937621 Ki 1.75 nM
COc1cc2c(cc1OCc1ccccc1)c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1 CHEMBL270987 Log Ki 1.778 nM
CC1(C)C(C(=O)c2cn(CCn3cccc3)c3ccccc23)C1(C)C CHEMBL570198 pKi 1.778 nM
CC1(C)C(C(=O)c2cn(CCc3ccsc3)c3ccccc23)C1(C)C CHEMBL571342 pKi 1.778 nM
CCCCCCc1cc(O)c2c(c1)OC(C)(C)C1=C2CCN(C)C1 CHEMBL525381 Ki 1.78 nM
CCCCCOc1c(OC)ccc2c1CCN(CCc1ccc(O)cc1)C2=O CHEMBL3410825 pKi 1.799 nM
C[C@H](NS(C)(=O)=O)c1ccc(Cc2ccc(C(F)(F)F)cc2S(=O)(=O)c2c(F)cccc2F)cc1 CHEMBL197904 Ki 1.8 nM
Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cccc(C(F)(F)F)c2F)n1CC1CC1 CHEMBL410014 EC50 1.8 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(C#N)c2ccccc12 CHEMBL482357 Ki 1.8 nM
CCCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL571773 Ki 1.8 nM
CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1271295 Ki 1.8 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1cccc(Cl)c1 CHEMBL1641955 Ki 1.8 nM
O=C(NC1CCCCCC1)c1c(O)c2cccnc2n(CCN2CCOCC2)c1=O CHEMBL2022694 Ki 1.8 nM
CCOC1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)c2ccccc21 CHEMBL2338175 EC50 1.8 nM
CCCCCOc1ccccc1-c1cc(C(=O)NC2CCCCCCC2)no1 CHEMBL2414036 EC50 1.8 nM
COc1cccc2c(C(=O)c3ccc(Br)c4ccccc34)c(C)n(CCN3CCOCC3)c12 CHEMBL3234669 Ki 1.8 nM
C/C(COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1)=N\O CHEMBL3686324 Ki 1.8 nM
CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686342 Ki 1.8 nM
CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)nn1CCCC(F)(F)F CHEMBL3650103 Ki 1.8 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCCC12CC2 CHEMBL3961521 EC50 1.8 nM
CCCCCCC(C)(C)c1ccc(C2CC(O)CCC2CCCO)c(O)c1 CHEMBL77520 Ki 1.8 nM
O=C(NC1(CO)CCCCC1)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3937051 EC50 1.8 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCCF)c(C3CC3)cn2)no1 CHEMBL3921971 EC50 1.8 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C3(C(=O)OCCCCC#N)CCC3)cc1OC2(C)C CHEMBL4063822 Ki 1.8 nM
CCCCN1C(=O)C(C(=O)NC23CC4CC(CC(C4)C2)C3)=C(O)C2C1C=NN2C CHEMBL4635230 Ki 1.8 nM
C=CCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccccc3)ccc21 CHEMBL2087104 Ki 1.82 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(=O)C[C@@H]21 CHEMBL947 Ki 1.84 nM
CC1CCC(NC(=O)c2cc3cc(-c4cccs4)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353444 Ki 1.85 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(O)cc23)C1(C)C CHEMBL270955 Ki 1.9 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(C#N)c2c1CCCC2 CHEMBL481888 Ki 1.9 nM
CC1CCC(NC(=O)c2cc3cccnc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL466223 Ki 1.9 nM
CN(C)CCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL569993 Ki 1.9 nM
Cc1cnc(NC(=O)C2(C)CCCCC2C)cc1CN1CCOCC1 CHEMBL568564 Ki 1.9 nM
CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)cc1-c1ccccc1 CHEMBL1641947 EC50 1.9 nM
CCCCCn1cc(C(=O)N[C@@H]2CCCc3ccccc32)c(=O)cc1-c1ccccc1 CHEMBL1641948 EC50 1.9 nM
CCCCCOc1ccccc1-c1cc(C(=O)NC2CCCCC2)no1 CHEMBL2414033 EC50 1.9 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nc2c(-c3ccccc3)cccc2[nH]1 CHEMBL3114524 EC50 1.9 nM
CCCCCOc1ccc(C(=O)NCCc2ccc(N)cc2)cc1SCCCCC CHEMBL3410812 Ki 1.9 nM
CNC(=O)C(NC(=O)c1cc(O[C@@H](C)C(F)(F)F)c(C2CC2)cn1)C(C)(C)O CHEMBL3906084 EC50 1.9 nM
Cc1ccn(Cc2ccc(F)cc2)c(=O)c1C(=O)NC1CCCCCC1 CHEMBL4175577 EC50 1.9 nM
Cc1nc(OCCCCCn2cc(CCCn3cc(Br)c(C)c(NC(=O)C4CCCCCC4)c3=O)nn2)c(C(=O)NC2CCCCCC2)cc1Br CHEMBL5204176 Ki 1.9 nM
CCOc1ccc(Nc2nc3cc(C(=O)N(CC)CC)ccc3n2CCC(C)C)cc1 CHEMBL4079520 Ki 1.9 nM
CCCCCn1c(C)c(C(=O)c2ccc(OC)c3ccccc23)c2ccccc21 CHEMBL564888 pKi 1.901 nM
CCCCCn1cc(C(=O)c2cccc3cc(OC)ccc23)c2ccccc21 CHEMBL563929 pKi 1.901 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CCCC1 CHEMBL108868 Log Ki 1.905 nM
CCCNC(=O)c1c(NC(=O)C23CC4CC(CC2C4)C3)sc2c1CCOC2 CHEMBL2010898 pIC50 1.95 nM
CCCNC(=O)c1c(NC(=O)C23CC4CC(CC2C4)C3)sc2c1CCCC2 CHEMBL2010902 pKi 1.95 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL74415 Log Ki 1.98 nM
CCCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL571550 pKi 1.995 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3cccc(CN4CCCC(F)(F)C4)n3)cc2)C1=O CHEMBL1835217 pEC50 1.995 nM
O=C1CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C(=O)N1CC1CC1 CHEMBL1835133 pEC50 1.995 nM
COc1cccc2c(C(=O)NC3C(C)(C)[C@@H]4CC[C@@]3(C)C4)nn(CCN3CCOCC3)c12 CHEMBL294591 Ki 2.0 nM
CCCCCCC(C)(C)c1cc(O)c(-c2cc(C)cc(C)c2)c(O)c1 CHEMBL56288 Ki 2.0 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2)cc1 CHEMBL198164 Ki 2.0 nM
CCOCCn1c(C)c(C(C)(C)C)s/c1=N\C(=O)c1cccc(C(F)(F)F)c1 CHEMBL248015 EC50 2.0 nM
Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCS(=O)(=O)CC1 CHEMBL254325 EC50 2.0 nM
Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCCCCC1 CHEMBL252878 EC50 2.0 nM
Cc1ccc(C(=O)Nc2ccccc2C(F)(F)F)cc1S(=O)(=O)N1CCCCC1 CHEMBL253260 EC50 2.0 nM
CN(Cc1ccc(-c2ccccc2C(F)(F)F)cc1)CC(O)c1ccccc1 CHEMBL494408 EC50 2.0 nM
CC(C)(O)CCn1c(=O)n(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 CHEMBL506652 EC50 2.0 nM
CCOc1ccc(Cc2nc3cc(N(C)C(=O)N(CC)CC)ccc3n2CC2CC2)cc1 CHEMBL462330 EC50 2.0 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC(F)(F)F)CC(F)(F)F)ccc3n2CC2CC2)cc1 CHEMBL510854 EC50 2.0 nM
CCCN(CCC)C(=O)c1ccc2c(c1)nc(Cc1ccc(OCC)cc1)n2CC1CC1 CHEMBL507572 EC50 2.0 nM
O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1cnc2ccccc2c1 CHEMBL476100 EC50 2.0 nM
O=S(=O)(c1ccccc1F)c1ccc(C(F)(F)F)cc1S(=O)(=O)N1CCC2(CC1)CC2NS(=O)(=O)C(F)(F)F CHEMBL595706 Ki 2.0 nM
CC(C)(C)c1ccc2oc(N3CCCN(C(=O)CC4CCCC4)CC3)nc2c1 CHEMBL1800750 EC50 2.0 nM
O=C(NC1CCCCCC1)c1cc2ccccc2n(CCN2CCOCC2)c1=O CHEMBL2022364 Ki 2.0 nM
CCCCCCCCC/C=C/C=C/C(=O)NCC(C)(C)O CHEMBL452912 IC50 2.0 nM
CC1CN1S(=O)(=O)c1ccc2c(c1)C1(OCCCO1)C(=O)N2CC1CC1 CHEMBL3235054 EC50 2.0 nM
COc1cccc2c(C(=O)N[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)nn(CCN3CCOCC3)c12 CHEMBL3235057 Ki 2.0 nM
CN1CC(S(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)C1 CHEMBL3357365 EC50 2.0 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2Cc2ccccc2)no1 CHEMBL3354528 EC50 2.0 nM
CN1C[C@H](F)C[C@H]1COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686314 Ki 2.0 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@H](C)O)sc2ccncc21 CHEMBL3647328 Ki 2.0 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3955150 EC50 2.0 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)C(=O)N(C)C)no1 CHEMBL3986505 EC50 2.0 nM
NC(=O)CC1(NC(=O)c2cc(OCC(F)(F)F)c(C3CCC3)cn2)CS(=O)(=O)C1 CHEMBL3957242 EC50 2.0 nM
CC(CC(N)=O)(NC(=O)c1cc(OCC(F)(F)F)c(C2(F)CCC2)cn1)C1CC1 CHEMBL3985919 EC50 2.0 nM
Cc1cc(-c2cc(C(=O)N[C@H]3CC[C@@H](C)CC3)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl CHEMBL4088509 Ki 2.0 nM
CCCCCn1/c(=N/C(=O)c2cccc3ccccc23)sc2ccccc21 CHEMBL4559193 Ki 2.0 nM
CCCCCn1nc(C(=O)NC(C)(C)CO)c(Br)c1C(C)(C)C CHEMBL4796229 EC50 2.0 nM
CC1=C(CCN2CCOCC2)c2ccccc2/C1=C/c1cccc2ccccc12 CHEMBL123916 Ki 2.05 nM
Cc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)c(C)n1CC1CC1 CHEMBL248386 IC50 2.1 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2cc(C(F)(F)F)ccc2Cl)n1CC1CC1 CHEMBL555610 IC50 2.1 nM
CCc1ccccc1NC(=O)CSc1nnc(-c2ccccc2OC)n1-c1ccccc1 CHEMBL496781 Ki 2.1 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC2CC2)cc1 CHEMBL472157 EC50 2.1 nM
CC1(C)C(C(=O)c2cn(CCCO)c3ccccc23)C1(C)C CHEMBL569299 Ki 2.1 nM
O=C(c1cn(CC2CCOCC2)c2ccccc12)C12CC3CC(CC1C3)C2 CHEMBL571999 Ki 2.1 nM
CC1(C)C(C(=O)c2cn(CCCCO)c3ccccc23)C1(C)C CHEMBL576706 EC50 2.1 nM
CCCCCn1c(C)c(C(=O)c2ccc(I)c3ccccc23)c2ccccc21 CHEMBL2206839 Ki 2.1 nM
CCCCCOc1ccccc1-c1cc(C(=O)NC2CCCC2)no1 CHEMBL2414032 EC50 2.1 nM
CC(C)(C)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354950 EC50 2.1 nM
CC(C)(NC(=O)c1nn(CCN2CCOCC2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354940 EC50 2.1 nM
Cc1c(C(=O)c2cccc3ccccc23)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL1222317 Ki 2.1 nM
Cn1cc2c(n1)c(O)c(C(=O)NC13CC4CC(CC(C4)C1)C3)c(=O)n2CCCCF CHEMBL4633927 Ki 2.1 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL85071 Ki 2.1 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCC(C)C(=O)NCCF CHEMBL309042 Log Ki 2.12 nM
CCOC(=O)c1c(NC(=O)C23CC4CC(CC(C4)C2)C3)sc2c1CCCC2 CHEMBL3909238 Ki 2.15 nM
CC1CCC(NC(=O)c2cc3cc(-c4ccc(F)cc4)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3353447 Ki 2.17 nM
O=C(NC1CCCCC1)c1cc2cccnc2n(Cc2ccc(F)cc2)c1=O CHEMBL508336 Ki 2.2 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CC3CC3)ccc2n1CC1CCN(C=O)CC1 CHEMBL1950925 EC50 2.2 nM
CCCCCn1c(C)c(C(=O)c2ccc(F)c3ccccc23)c2ccccc21 CHEMBL2206856 Ki 2.2 nM
O=C(NC1CCCCCC1)c1cc(Br)cn(Cc2ccc(F)cc2)c1=O CHEMBL3114178 Ki 2.2 nM
CCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 CHEMBL2414020 EC50 2.2 nM
CCC(CC)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)C(=O)OC CHEMBL3956773 EC50 2.2 nM
C[C@H](Oc1cc(C(=O)NC(C(=O)N2CCC2)C(C)(C)C)ncc1C1CC1)C(F)(F)F CHEMBL3894170 EC50 2.2 nM
CC1(C)Oc2cc(C34CC5CC(CC(CN=[N+]=[N-])(C5)O3)C4)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL4787347 Ki 2.2 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL5194443 Ki 2.21 nM
CC1(C)C(C(=O)c2cn(CCN3CCCCC3)c3ccccc23)C1(C)C CHEMBL570876 pKi 2.239 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(O)c1 CHEMBL56799 Ki 2.3 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(C(=O)OC)c1 CHEMBL233180 Ki 2.3 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1ccc(C#N)cc1 CHEMBL393045 Ki 2.3 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2C[C@H]2CCCCN2C)cc1 CHEMBL488310 EC50 2.3 nM
CC(C(=O)Nc1ccc2c(c1)C(N1CCOCC1)CCC2)(C(F)(F)F)C(F)(F)F CHEMBL567594 Ki 2.3 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3cccs3)ccc21 CHEMBL1215941 Ki 2.3 nM
CCCCCn1c(C)c(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc21 CHEMBL2206860 Ki 2.3 nM
Cc1cccc(-c2c(O)cc(C(C)(C)c3ccccc3)cc2O)c1 CHEMBL3922001 Ki 2.3 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C(F)(F)F)c(OCC2CCCO2)n1 CHEMBL3929723 EC50 2.3 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3944149 EC50 2.3 nM
NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1ccc(C2(F)CCC2)c(OCC2CC2)n1 CHEMBL3967364 EC50 2.3 nM
Cc1nc([C@](C)(CC(C)(C)C)NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)no1 CHEMBL3918668 EC50 2.3 nM
CC(C)(NC(=O)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21)C(F)(F)F CHEMBL4172104 EC50 2.3 nM
COc1cc(C(=O)c2cccs2)cc(O)c1-c1cc(Cl)cc(Cl)c1 CHEMBL1081624 Ki 2.32 nM
CCCC1COc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163937 Ki 2.34 nM
CCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c12 CHEMBL1822930 pKi 2.399 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(C4CCOCC4)no3)ccc21 CHEMBL500655 EC50 2.4 nM
CCN(CC)C(=O)c1ccc2c(c1)nc(Cc1ccc(OC(C)C)cc1)n2CCC(C)C CHEMBL453846 EC50 2.4 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc([N+](=O)[O-])c2ccccc12 CHEMBL519635 Ki 2.4 nM
Cc1c(C(=O)N[C@@H](C)C2CCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1 CHEMBL573546 Ki 2.4 nM
CCCCCn1cc(C(=O)N[C@H]2C(C)(C)[C@H]3CC[C@]2(C)C3)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL1216001 Ki 2.4 nM
CCCCCn1cc(C(=O)NC2C(C)(C)[C@@H]3CC[C@@]2(C)C3)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL1668517 Ki 2.4 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CCCC(F)(F)F)ccc2n1CC1CCN(C=O)CC1 CHEMBL1950837 EC50 2.4 nM
O=C(NC1CCCCC1)c1c(O)c2cccnc2n(CCN2CCOCC2)c1=O CHEMBL2022692 Ki 2.4 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)no1 CHEMBL3353868 EC50 2.4 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1 CHEMBL3983354 EC50 2.4 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C2CC2)c(S(=O)(=O)CC(C)C)n1 CHEMBL3906625 EC50 2.4 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCC(F)(F)F)c(C3CCC3)cn2)no1 CHEMBL3936122 EC50 2.4 nM
C[C@H](Oc1cc(C(=O)NC(C(=O)N(C)C)C(C)(C)C)ncc1C1CC1)C(F)(F)F CHEMBL3943441 EC50 2.4 nM
Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(OC(C)CF)c(C3CC3)cn2)no1 CHEMBL3943239 EC50 2.4 nM
Cc1c(Br)cn(Cc2ccccc2Cl)c(=O)c1NC(=O)C1CCCCCC1 CHEMBL4866198 EC50 2.4 nM
CCc1c(C)sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c1C(=O)OC CHEMBL2349625 Ki 2.46 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccco3)ccc21 CHEMBL2087108 Ki 2.48 nM
CCCCCn1ccc(C(=O)c2cccc3ccccc23)c1 CHEMBL71810 Log Ki 2.5 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc(C(C)C)c1 CHEMBL231719 Ki 2.5 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(Cl)ccc23)C1(C)C CHEMBL411674 Ki 2.5 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CCO)ccc2n1CC1CCOCC1 CHEMBL404458 EC50 2.5 nM
COC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2cc3cccnc3n2S(=O)(=O)c2ccccc2F)CC1 CHEMBL1271296 Ki 2.5 nM
CC(=O)NCCNC(=O)C(C)(C)NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2018662 Ki 2.5 nM
CC1(C)C2CC[C@](C)(C2)[C@@H]1NC(=O)c1cn(CCCCO)c2cc(Sc3ccccc3)ccc2c1=O CHEMBL2152818 Ki 2.5 nM
O=C(Nc1sc2c(c1C(=O)N1CC(F)(F)C1)CCOC2)c1ccccc1C(F)(F)F CHEMBL2205591 EC50 2.5 nM
CCN(CC)c1ccc(CN(c2ccccc2)S(=O)(=O)c2ccc(OC)cc2)cc1 CHEMBL2336543 EC50 2.5 nM
COC(=O)c1ccc2c(/C=C3/C(=O)C4CCN3CC4)cn(Cc3ccccc3)c2c1 CHEMBL2346979 Ki 2.5 nM
CCCCn1c2c(cc(C(=O)NC(C)C)c1=O)CCCCCC2 CHEMBL2387182 IC50 2.5 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nn(-c2ccc(Cl)c(Cl)c2)c2c1CCCC2 CHEMBL3234680 EC50 2.5 nM
CCCCCOc1cc(C(=O)NCCc2ccc(O)cc2)ccc1OC CHEMBL3410829 Ki 2.5 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(O[11CH3])C2)c(OCC2CC2)n1 CHEMBL3582029 Ki 2.5 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(OC)C2)c(OCC2CC2)n1 CHEMBL3582008 Ki 2.5 nM
CC(C)(O)COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc2ccncc2n1CC1CCC1 CHEMBL3647325 Ki 2.5 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1O/N=C(\N)C1CC1 CHEMBL3650125 Ki 2.5 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2NNC(=O)c2cccnc2)cc(C(C)(C)C)n1C CHEMBL3650135 Ki 2.5 nM
CNC(=O)[C@H](CC(C)(C)C)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3972519 EC50 2.5 nM
CC(C)(CCc1ccccc1)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3965458 EC50 2.5 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCN3CCCCC3)cc1OC2(C)C CHEMBL4243768 Ki 2.5 nM
CC1=C(C(=O)c2cccc3ccccc23)C2C=CC=C3OC[C@@H](CN4CCOCC4)N1C32 CHEMBL4439452 Ki 2.5 nM
CCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(O)c2nn(C)cc21 CHEMBL4640659 Ki 2.5 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCF CHEMBL74909 Log Ki 2.51 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCS(=O)(=O)CC4)n3)cc2)C1=O CHEMBL1835220 pEC50 2.512 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(C)C4)n3)cc2)C1=O CHEMBL1835213 pEC50 2.512 nM
O=C1CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C(=O)N1CC(F)F CHEMBL1835135 pEC50 2.512 nM
O=C1CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C(=O)N1CC1CCC1 CHEMBL1835134 pEC50 2.512 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C1=O CHEMBL1835131 pEC50 2.512 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C1=O CHEMBL1835119 pEC50 2.512 nM
C[C@H](CO)NC(=O)CCC/C=C\C/C=C\CCOc1cccc(C(C)(C)CCCCN=[N+]=[N-])c1 CHEMBL240315 Ki 2.52 nM
O=C(NC1CCCCC1)c1cn2c3c(cccc3c1=O)OCC2c1ccccc1 CHEMBL2163949 Ki 2.52 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3ccc(C#N)cc3)cc1OC2(C)C CHEMBL472115 Ki 2.53 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccccc3)cc12 CHEMBL2381786 Ki 2.56 nM
COc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 CHEMBL2414018 EC50 2.56 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO CHEMBL15848 Log Ki 2.57 nM
O=C(c1cn(CC2CCOCC2)c2ccccc12)[C@@H]1CC12CCCCC2 CHEMBL3085420 pKi 2.57 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC(C)CO CHEMBL55802 Log Ki 2.6 nM
CCOc1ccc(Cc2nc3cc(N(C)C(=O)c4cccs4)ccc3n2CC2CC2)cc1 CHEMBL518206 EC50 2.6 nM
CN1CC(S(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CCOC(F)(F)F)C1 CHEMBL3357380 EC50 2.6 nM
CNC(=O)C(NC(=O)c1cc(O[C@@H](C)C(F)(F)F)c(C2CC2)cn1)C(C)(C)C CHEMBL3894051 EC50 2.6 nM
Cc1cc(-c2cc(C(=O)N[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl CHEMBL4067246 Ki 2.6 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C=O)C[C@@H]21 CHEMBL59540 Ki 2.61 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCOC CHEMBL75591 Log Ki 2.65 nM
CCCCN1Cc2c(n(S(=O)(=O)CC)c3ccc(C(=O)N4CCC(C)CC4)cc23)C1 CHEMBL250808 EC50 2.7 nM
CCOc1ccc(Cc2nc3cc(N(C)C(=O)CC(C)C)ccc3n2CC2CC2)cc1 CHEMBL517283 EC50 2.7 nM
Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(CN2CCOCC2)c1C CHEMBL568467 Ki 2.7 nM
CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCCCC2)c1 CHEMBL602105 Ki 2.7 nM
CCC(C)(C)C(=O)Cc1cc(C)c(C)c(S(=O)(=O)N2CCCCC2)c1 CHEMBL1668514 Ki 2.7 nM
CC(C)(C)c1ccc(NC(=O)N2CCCN(C(=O)c3ccc(C(F)(F)F)cc3)CC2)cc1 CHEMBL1762290 EC50 2.7 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CC1 CHEMBL1800168 EC50 2.7 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2cccc(S(=O)(=O)NC3CC3)c2)n1 CHEMBL3669072 IC50 2.7 nM
CNC(=O)[C@H](CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1 CHEMBL3961453 EC50 2.7 nM
CNC(=O)[C@@H](NC(=O)c1cccc(-c2ccc(F)c(Cl)c2)n1)C(C)(C)C CHEMBL4109654 EC50 2.7 nM
CCC(CC)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CCCO2)n1)C(=O)N(C)C CHEMBL3917096 EC50 2.7 nM
NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3930382 EC50 2.7 nM
CC(C)C[C@H](NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(=O)N(C)C CHEMBL3959188 EC50 2.7 nM
Cc1nc(C(NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CC3)cn2)C(C)(C)C)no1 CHEMBL3918476 EC50 2.7 nM
COc1ccc(-c2oc3ccccc3c2C(=O)c2ccc(N(C)Cc3ccc(F)cc3)cc2)cc1 CHEMBL4530405 Ki 2.7 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2cccc(F)c21 CHEMBL4516360 Ki 2.7 nM
CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(OC(C)C)c1 CHEMBL4644161 Ki 2.7 nM
C1=C(CCN2CCOCC2)c2ccccc2/C1=C/c1cccc2ccccc12 CHEMBL127644 Ki 2.72 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N1CCOCC1 CHEMBL73987 Log Ki 2.73 nM
CC1(C)C(C(=O)c2cn(CCC3CCOCC3)c3ccccc23)C1(C)C CHEMBL572192 pKi 2.754 nM
CC1(C)C(C(=O)c2cn(CCc3cccs3)c3ccccc23)C1(C)C CHEMBL569300 pKi 2.754 nM
CCN(CC)c1ccc(CN(c2ccc(Cl)cc2)S(=O)(=O)c2cccc(C)c2)cc1 CHEMBL2326290 pKi 2.799 nM
CCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc(F)cc3)c(=O)[nH]c12 CHEMBL1822928 Ki 2.8 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NN CHEMBL2018780 Ki 2.8 nM
CCCCCn1c(C)c(C(=O)c2ccc(Br)c3ccccc23)c2ccccc21 CHEMBL2206835 Ki 2.8 nM
CCCCCn1cc(C(=O)c2ccc(Cl)c3ccccc23)c2ccccc21 CHEMBL2206859 Ki 2.8 nM
CCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc([18F])cc3)c(=O)[nH]c12 CHEMBL3093358 Ki 2.8 nM
O=C(NC1CCCCCC1)c1cc(-c2ccc(F)cc2)cn(Cc2ccc(F)cc2)c1=O CHEMBL3114341 Ki 2.8 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 CHEMBL3353870 EC50 2.8 nM
CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)nn1CC1CCC1 CHEMBL3650104 Ki 2.8 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(Br)c(OCC2CC2)n1 CHEMBL3966833 EC50 2.8 nM
CSCC[C@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(N)=O CHEMBL3898565 EC50 2.8 nM
CCN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C1(C(F)(F)F)CC1 CHEMBL3896334 EC50 2.8 nM
CCCCCNC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL4089791 Ki 2.8 nM
CCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL2387541 Ki 2.8 nM
CCCCCn1c(=O)c(C(=O)NC2CCC(C)CC2)cc2cccnc21 CHEMBL3353424 Ki 2.82 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccccc3C)cc12 CHEMBL2381788 Ki 2.86 nM
CCCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 CHEMBL2414021 EC50 2.88 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL561013 pKi 2.897 nM
CC1=CC[C@@H]2[C@@H](C1)c1ccc(CCCCCC(C)(C)C)cc1OC2(C)C CHEMBL2112646 Ki 2.9 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCCC#N)cc1OC2(C)C CHEMBL138917 Ki 2.9 nM
CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3cc(OCc4ccccc4)ccc23)C1(C)C CHEMBL411937 Ki 2.9 nM
CC(C)(C)c1ncc(NC(=O)CCc2nc(-c3ccc(F)cc3Cl)no2)cn1 CHEMBL499059 EC50 2.9 nM
COC(=O)CCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL570877 Ki 2.9 nM
CCCCCCC(C)(C)c1cc(N)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL604746 Ki 2.9 nM
CCCCCCC(C)(C)c1ccc2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL57723 Ki 2.9 nM
CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 CHEMBL1800163 EC50 2.9 nM
CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)c4ccc(F)cc4)ccc32)CC1 CHEMBL1950931 EC50 2.9 nM
O=C(NC1CCCCC1)c1cc2ccccc2n(Cc2ccc(F)cc2)c1=O CHEMBL2022361 Ki 2.9 nM
CCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152801 Ki 2.9 nM
CCCCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 CHEMBL2414022 EC50 2.9 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1 CHEMBL3582024 EC50 2.9 nM
C[C@H](Oc1cc(C(=O)NC(c2nnn(C)n2)C(C)(C)C)ncc1C1CC1)C(F)(F)F CHEMBL3973847 EC50 2.9 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCBr)cc1OC2(C)C CHEMBL4084380 Ki 2.9 nM
CCCCCn1nc(C(=O)NC(C)(C)CO)cc1C(C)(C)C CHEMBL4795720 EC50 2.9 nM
O=C(c1ccccc1)c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1 CHEMBL460545 Ki 2.94 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(S(C)(=O)=O)ccc23)C1(C)C CHEMBL271527 Log Ki 2.951 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL2326296 pKi 2.999 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)ccc2C(C)C)c(O)c1 CHEMBL125061 Ki 3.0 nM
O=C(c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1)N1CC[C@@H]2CCCC[C@H]2C1 CHEMBL252044 EC50 3.0 nM
O=C(NC1CCCCC1)c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1 CHEMBL254731 EC50 3.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(Cl)cc23)C1(C)C CHEMBL410676 Ki 3.0 nM
O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1nc2ccc(OC(F)(F)F)cc2s1 CHEMBL499328 EC50 3.0 nM
Cc1ccc(Cl)c(-c2ccc(CN3CCO[C@@H](c4ccccc4)C3)cc2)c1 CHEMBL442848 EC50 3.0 nM
N#Cc1ccccc1-c1ccc(CN2CCO[C@@H](c3ccccc3)C2)cc1 CHEMBL494995 EC50 3.0 nM
CCOc1ccc(Cc2nc3cc(C(=O)N4CCCCC4)ccc3n2CC2CC2)cc1 CHEMBL453844 EC50 3.0 nM
Fc1ccc(-c2noc(C3CCN(c4cnc5ccc(OC(F)(F)F)cc5c4)CC3)n2)c(Cl)c1 CHEMBL469040 EC50 3.0 nM
O=C(NC1CCCCCC1)c1cc2cccnc2n(CCN2CCOCC2)c1=O CHEMBL467475 Ki 3.0 nM
O=S(=O)(c1ccccc1F)c1cc(Cl)ccc1S(=O)(=O)N1CCC(CO)(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL594300 Ki 3.0 nM
O=S(=O)(c1ccccc1F)c1ccc(OC(F)(F)F)cc1S(=O)(=O)N1CCC2(CC1)CC2NS(=O)(=O)C(F)(F)F CHEMBL596356 Ki 3.0 nM
COc1ccc(-c2c[nH]c(-c3cccc(CN4CCC(F)(F)CC4)c3)n2)c(F)c1 CHEMBL1644733 EC50 3.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3c(COc4ccccc4)cccc23)C1(C)C CHEMBL1668396 Ki 3.0 nM
O=C(NCC1(CO)CCCC1)c1nc(CN2CCC(F)(F)CC2)n2ccccc12 CHEMBL1760935 IC50 3.0 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(C(N)=O)CC1 CHEMBL2018666 Ki 3.0 nM
O=C(N[C@@H](C(=O)O)c1ccccc1)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2023046 Ki 3.0 nM
O=C(Nc1sc2c(c1C(=O)N1CCCCC1)CCOC2)c1ccccc1C(F)(F)F CHEMBL2205615 EC50 3.0 nM
CCCCOC(=O)C1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)CCC1 CHEMBL3104362 Ki 3.0 nM
CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)C4CCCC4)ccc32)CC1 CHEMBL1950928 EC50 3.0 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2Cc2ccc(Cl)cc2)no1 CHEMBL3354529 EC50 3.0 nM
CC(C)(CO)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@@H]1C[C@H]21 CHEMBL3354963 EC50 3.0 nM
CC(C)(C)c1cc(NC(=O)C(C)(C)S(=O)(=O)c2ccc(C(F)(F)F)cn2)no1 CHEMBL3400947 EC50 3.0 nM
CN1C[C@@H](F)C[C@H]1COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686312 Ki 3.0 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@H]2CCCO2)s1 CHEMBL3686292 Ki 3.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(Cl)c(S(=O)(=O)N3CCOCC3)c2)n1 CHEMBL3669109 IC50 3.0 nM
CC(C)C[C@@H](CO)NC(=O)c1ccc(N2CCCC2)c(OCC2CC2)n1 CHEMBL3899636 EC50 3.0 nM
CC(C)(C)C(NC(=O)c1cc(OCC2CC2)c(N2CC(F)(F)C2)cn1)C(N)=O CHEMBL3953148 EC50 3.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3c(OCc4ccccc4)cccc23)C1(C)C CHEMBL271565 Log Ki 3.02 nM
CC1(C)Oc2cc(C3(CCCCCCBr)CCCC3)cc(O)c2[C@@H]2CC(=O)CC[C@H]21 CHEMBL1259038 Ki 3.02 nM
NC(=O)[C@@H]1CC(F)(F)CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3948332 EC50 3.075 nM
COCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL570690 Ki 3.1 nM
CC[C@]1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)C[C@H]1C CHEMBL1270287 Ki 3.1 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)CC(C)(C)O)ccc2n1CC1CC1 CHEMBL1800165 EC50 3.1 nM
CCCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1OCC(N)=O CHEMBL3647301 Ki 3.1 nM
CCC(CC)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 CHEMBL3950068 EC50 3.1 nM
CC1(C)COCN1C(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1 CHEMBL3941906 EC50 3.1 nM
O=C(N[C@H](c1ccccn1)C(F)(F)F)c1cc(OCC2CC2)c(Cl)cn1 CHEMBL4112196 EC50 3.1 nM
CC1(C)Oc2cc(C34CC5CC(CC(CN=[N+]=[N-])(C5)O3)C4)cc(O)c2[C@@H]2C[C@H](O)CC[C@H]21 CHEMBL4795739 Ki 3.1 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)oc(=O)c1ccc(C)cc12 CHEMBL113230 Ki 3.1 nM
O=C(NC1CCCCCC1)c1cn2c3c(cccc3c1=O)OCC2C1CC1 CHEMBL2163942 Ki 3.12 nM
C[C@H](CO)NC(=O)CCC/C=C\C/C=C\CCOc1cccc(C(C)(C)CCCC#N)c1 CHEMBL393344 Ki 3.13 nM
CC(C)(CCCCCCN=C=S)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21 CHEMBL5085420 Ki 3.15 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(N)cc3)c(O)nc12 CHEMBL382676 Log IC50 3.162 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3c(O)cccc23)C1(C)C CHEMBL270082 Log Ki 3.162 nM
O=C1CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C(=O)N1CC(F)(F)F CHEMBL1835128 pEC50 3.162 nM
O=C1CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C(=O)N1CC1CC1 CHEMBL1835126 pEC50 3.162 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)CCCCC(=O)NN3CCCCC3)cc1OC2(C)C CHEMBL138772 Ki 3.2 nM
CCCN(C)C(=O)c1ccc2c(c1)nc(Cc1ccc(OCC)cc1)n2CC1CC1 CHEMBL454607 EC50 3.2 nM
CCN(CC)C(=O)c1ccc2c(c1)nc(Cc1ccc(Oc3ccccc3)cc1)n2CCC(C)C CHEMBL510072 EC50 3.2 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 CHEMBL1641945 EC50 3.2 nM
CC(C)S(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 CHEMBL1800654 EC50 3.2 nM
CCCCCn1cc(C(=O)c2ccc(F)c3ccccc23)c2ccccc21 CHEMBL2206855 Ki 3.2 nM
CC(C)(NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354943 EC50 3.2 nM
CN(C)C(=O)[C@H](CC1CC1)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3899121 EC50 3.2 nM
CC(C)(C)C(NC(=O)c1cc(OCC2CC2)c(C2CC2)cn1)c1nccs1 CHEMBL3917714 EC50 3.2 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2c(C)c(C)sc21 CHEMBL2316259 Ki 3.27 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1F CHEMBL216857 Ki 3.3 nM
C=C(CCCCCC)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL239840 Ki 3.3 nM
COc1cccc2c1c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1 CHEMBL408964 Ki 3.3 nM
CCOc1ccc(Cc2nc3cc(N(C)C(=O)N4CCCCC4)ccc3n2CC2CC2)cc1 CHEMBL458142 EC50 3.3 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2Cc2ccco2)cc1 CHEMBL472121 EC50 3.3 nM
CC1(C)C(C(=O)c2cn(C[C@@H]3CCCO3)c3ccccc23)C1(C)C CHEMBL571777 Ki 3.3 nM
CCCCCn1cc(C(=O)c2cccc3cccc(I)c23)c2ccccc21 CHEMBL2206850 Ki 3.3 nM
O=C(Nc1sc2c(c1C(=O)N1CCC(F)(F)CC1)CCOC2)c1ccccc1OC(F)(F)F CHEMBL2205595 EC50 3.3 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(C)CC)ccc3n2CCC(C)C)cc1 CHEMBL3127262 Ki 3.3 nM
CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(OC)c21 CHEMBL3409149 Ki 3.3 nM
CC(=O)/C(C)=N/Oc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686333 Ki 3.3 nM
O=C(N[C@@H](c1cccnc1)C(F)(F)F)c1cc(Cc2ccc(F)cc2)c(Cl)cn1 CHEMBL3908763 EC50 3.3 nM
[11CH3]OC(=O)c1c(NC(=O)C23CC4CC(CC(O)(C4)C2)C3)sc2c1CCCC2 CHEMBL4099487 Ki 3.3 nM
Cc1c(Cl)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4781952 EC50 3.3 nM
COC(=O)c1c(NC(=O)C23CC4CC(CC(O)(C4)C2)C3)sc2c1CCCC2 CHEMBL4117628 Ki 3.3 nM
O=C(c1ccc2ccccc2c1)c1cn2c3c(cccc13)OCC2CN1CCOCC1 CHEMBL5270707 Ki 3.3 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CCC(=O)C[C@@H]32)CCCC1 CHEMBL1259244 Ki 3.34 nM
O=C(c1cnc2ccccc2c1)N1CC[C@@](O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765258 IC50 3.38 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2ccccc2)cc1 CHEMBL2326294 pKi 3.396 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1CC CHEMBL220352 Ki 3.4 nM
CN1CCCCC1Cn1cc(C(=O)c2cc([N+](=O)[O-])ccc2I)c2ccccc21 CHEMBL408430 IC50 3.4 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(Sc3ccccc3)ccc21 CHEMBL524456 Ki 3.4 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2C[C@@H]2CCCN2C)cc1 CHEMBL519592 EC50 3.4 nM
CCCCC1=NN(C(=O)N[C@H]2C[C@H]3CC[C@]2(C)C3(C)C)C(C)(C)C1c1ccccc1 CHEMBL1223775 Ki 3.4 nM
CCCCCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 CHEMBL2414023 EC50 3.4 nM
NC(=O)[C@@H]1CS(=O)(=O)CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3983760 EC50 3.4 nM
Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CC3)cn2)no1 CHEMBL3893170 EC50 3.4 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCC(F)F)c(C3CC3)cn2)no1 CHEMBL3943882 EC50 3.4 nM
CN(C)C(=O)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(C)(C)C CHEMBL3907596 EC50 3.4 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(C3(F)CCC3)cn2)C2CC2)no1 CHEMBL3978407 EC50 3.4 nM
Cc1cc(-c2cc(C(=O)NC34CC5CC(CC(C5)C3)C4)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl CHEMBL4091845 Ki 3.4 nM
CCCCCn1nc(C(=O)NC(C)(C)CO)c(Cl)c1C(C)(C)C CHEMBL4783200 EC50 3.4 nM
Cc1c(Br)cn(Cc2ccccc2F)c(=O)c1NC(=O)C1CCCCCC1 CHEMBL4856531 EC50 3.4 nM
CCCC(C)(C)c1ccc2c(c1)OC(C)(C)C1CC=C(C)CC21 CHEMBL5285808 Ki 3.4 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccc(C)cc3)cc12 CHEMBL2381791 Ki 3.41 nM
CC12CC3CC(C)(C1)CC(NC(=O)c1cn4c5c(cccc5c1=O)OCC4c1ccccc1)(C3)C2 CHEMBL2163952 Ki 3.45 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O CHEMBL190461 Log Ki 3.46 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(C(F)(F)F)ccc23)C1(C)C CHEMBL410441 Log Ki 3.467 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(CO)cc1-2 CHEMBL5192756 Ki 3.49 nM
C[C@H](NS(C)(=O)=O)c1ccc(Cc2ccc(C(F)(F)F)cc2S(=O)(=O)c2cccc(F)c2)cc1 CHEMBL198251 Ki 3.5 nM
CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(S(=O)(=O)N2CCOCC2)c1 CHEMBL256962 Ki 3.5 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccc([S+]([O-])c3ccccc3)cc21 CHEMBL496659 Ki 3.5 nM
Cc1nc(C(=O)Nc2ccccc2C(F)(F)F)c(C)n1-c1ccccc1 CHEMBL1668504 Ki 3.5 nM
O=C(O)Cc1cnc(NC(=O)c2cc3c(n(CC4CCCCC4)c2=O)CCCCCC3)s1 CHEMBL2023582 IC50 3.5 nM
CCOC(=O)c1c(C)cc2nc(COC(=O)NCCO)n(-c3ccccc3S(=O)(=O)NC)c(=O)c2c1C CHEMBL2397751 IC50 3.5 nM
Cc1nc([C@H](CC2CC2)NC(=O)c2cccc(-c3ccc(F)c(Cl)c3)n2)no1 CHEMBL3958669 EC50 3.5 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2ccc(-c3ccccc3)cc21 CHEMBL2087110 Ki 3.52 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cccc(Cl)c3)cc1OC2(C)C CHEMBL521366 Ki 3.54 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccccc3)nc12 CHEMBL2316262 Ki 3.58 nM
Cc1cc(C)cc(-c2ccc(C(C)(C)CCCCCO)cc2O)c1 CHEMBL234675 Ki 3.6 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)SCCCS1 CHEMBL108392 Ki 3.6 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(F)c(-n3cccc3)cc21 CHEMBL497321 Ki 3.6 nM
Fc1ccc(-c2noc(CCCOc3cnc4ccc(Cl)cc4c3)n2)c(Cl)c1 CHEMBL498469 EC50 3.6 nM
O=C(Nc1sc2c(c1C(=O)N1CCC(F)(F)CC1)CCOC2)c1c(F)cccc1C(F)(F)F CHEMBL2205596 EC50 3.6 nM
CC1CCC(NC(=O)c2cc3cccnc3n(CCCCCO)c2=O)CC1 CHEMBL3353428 Ki 3.6 nM
O=C(CCCOc1ccc(Cl)cc1Cl)NN/C=C1\C=CC=CC1=O CHEMBL3686341 Ki 3.6 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 CHEMBL3960116 EC50 3.6 nM
Cc1cnc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)s1 CHEMBL3960251 EC50 3.6 nM
CCCCCCC(C)(C)c1cc(OCCO)c2c(c1)OC(C)(C)c1cn[nH]c1-2 CHEMBL4557358 Ki 3.6 nM
CC1(C)Oc2cc(C34CC5CC(CC(CN=C=S)(C5)O3)C4)cc(O)c2[C@@H]2C[C@H](O)CC[C@H]21 CHEMBL4779296 Ki 3.6 nM
CCCC1COc2cccc3c(=O)c(C(=O)NC45CC6CC(C)(CC(C)(C6)C4)C5)cn1c23 CHEMBL2163938 Ki 3.62 nM
CC1(C)C(C(=O)c2cn(Cc3ccncc3)c3ccccc23)C1(C)C CHEMBL570908 pKi 3.631 nM
CC(C)c1cc(N2CCOCC2)nnc1C(=O)NC1C2CC3CC(C2)CC1C3 CHEMBL4129867 EC50 3.665 nM
CCCCCOc1c(OC)ccc2c(=O)n(CCc3ccc(O)cc3)ccc12 CHEMBL3410822 pKi 3.698 nM
CCCCOC(=O)[C@H](C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL3104356 Ki 3.7 nM
CC(C)(CO)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354952 EC50 3.7 nM
CC(C)(C)NNc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686303 Ki 3.7 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC(F)(F)C[C@H]1CO CHEMBL3923278 EC50 3.7 nM
Cc1nc([C@](C)(CC2CC2)NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)no1 CHEMBL3941942 EC50 3.7 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCCn3ccnc3)cc1OC2(C)C CHEMBL4238224 Ki 3.7 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCC(C(=O)NCCO)C(C)C CHEMBL77801 Log Ki 3.71 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cn2c3c(cccc3c1=O)OC[C@H]2Cc1ccccc1 CHEMBL2163929 Ki 3.72 nM
CC(C)C1COc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163944 Ki 3.74 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C(=O)OC)cc1-2 CHEMBL420173 Ki 3.8 nM
COc1ccc(/N=C2\SCC3(CCCCC3)CN2C(=S)SC)cc1 CHEMBL231933 Ki 3.8 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccccc3)ccc21 CHEMBL523577 Ki 3.8 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccncc4C#N)no3)ccc21 CHEMBL499601 EC50 3.8 nM
CC1(C)C(C(=O)c2cn(C[C@H]3CCCO3)c3ccccc23)C1(C)C CHEMBL583680 Ki 3.8 nM
CC(C)(C)C(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(N)=O CHEMBL3892333 EC50 3.8 nM
COCC(C)(C)N(C)C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3968525 EC50 3.8 nM
CC(C)[C@@H](CF)NC(=O)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL4166597 EC50 3.8 nM
Cc1c(Br)cn(Cc2ccc(F)cc2)c(=O)c1NC(=O)C1CCCCCC1 CHEMBL4467500 EC50 3.8 nM
CCCCCn1cc(C(=O)c2cccc3ccc(CC)cc23)c2ccccc21 CHEMBL539994 pKi 3.802 nM
COc1ccc(-c2cnc3c(c2)cc(C(=O)NC2CCC(C)CC2)c(=O)n3Cc2ccc(F)cc2)cc1 CHEMBL3353443 Ki 3.83 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C3(C#N)CCCCC3)cc1OC2(C)C CHEMBL205888 Ki 3.86 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccc(Cl)cc3)cc12 CHEMBL2381797 Ki 3.88 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cccc(O)c23)C1(C)C CHEMBL259253 Log Ki 3.89 nM
Cc1ccc(C(=O)N[C@@H]2C(C)(C)[C@H]3CC[C@]2(C)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL255474 Ki 3.9 nM
Cc1ccc(C(=O)N[C@@H]2C(C)(C)[C@@H]3CC[C@@]2(C)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL516388 Ki 3.9 nM
Cc1ccc(C(=O)NC2C(C)(C)[C@@H]3CC[C@@]2(C)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL565969 Ki 3.9 nM
Cc1ccc(C(=O)NC2C(C)(C)[C@@H]3CC[C@]2(C)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL1668512 Ki 3.9 nM
CCCCn1c(=O)c(C(=O)NC2CCC(C)CC2)cc2cccnc21 CHEMBL3353423 Ki 3.9 nM
COc1ccc2c(c1)c(CCN1CCOCC1)c(C)n2C(=O)c1ccc(Cl)cc1Cl CHEMBL3409322 Ki 3.9 nM
COc1nc(NCCc2ccc(OCF)cc2)nc(-c2ccc(Cl)c(C(C)(C)O)c2)n1 CHEMBL3669062 IC50 3.9 nM
CNC(=O)[C@H](CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1 CHEMBL3899976 EC50 3.9 nM
NC(=O)[C@@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1ccc(F)cc1 CHEMBL3909476 EC50 3.9 nM
CCN1CCN(C(=O)c2cn3c4c(cccc24)OC[C@H]3C2CCCCC2)CC1 CHEMBL1209573 pKi 3.981 nM
COc1cccc2c(C(=O)N3CCN4CCCC[C@H]4C3)cn(CC3CCCCC3)c12 CHEMBL1287846 pKi 3.981 nM
O=C1CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C(=O)N1C1CCC1 CHEMBL1835125 pEC50 3.981 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1C CHEMBL220180 Ki 4.0 nM
CCCCN(C)C(=O)c1ccc2c(c1)c1c(n2S(=O)(=O)CC)CN(C2CCCC2)C1 CHEMBL399949 EC50 4.0 nM
O=C(c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1)N1CCC2CCCCC2C1 CHEMBL404540 EC50 4.0 nM
CC(C)c1ccc(C(=O)NC2CCCCC2)cc1S(=O)(=O)N1CCCC1 CHEMBL254730 EC50 4.0 nM
Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCCC1 CHEMBL252279 EC50 4.0 nM
Cc1ccc(C(=O)Nc2cccc3cccnc23)cc1S(=O)(=O)N1CCCCC1 CHEMBL254146 EC50 4.0 nM
Cc1ccc(C(=O)Oc2cccc3cccnc23)cc1S(=O)(=O)N1CCCCC1 CHEMBL245876 Ki 4.0 nM
CCOc1ccc(Cc2nc3cc(SCC)c(Cl)cc3n2CC2CCOCC2)cc1 CHEMBL403045 EC50 4.0 nM
CCOc1ccc(Cc2nc3cc(S(=O)(=O)CC)ccc3n2CC2CCOCC2)cc1 CHEMBL256781 EC50 4.0 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CCC#N)ccc2n1CC1CCOCC1 CHEMBL257612 EC50 4.0 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C1CC1)n2CC1CCOCC1 CHEMBL402281 EC50 4.0 nM
CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)C)n2CC1CCOCC1 CHEMBL403591 EC50 4.0 nM
O=C(Nc1cnc2ccccc2c1)C1(S(=O)(=O)c2ccccc2)CC1 CHEMBL467010 EC50 4.0 nM
CC(C)(C(=O)Nc1ccc(Cl)c(-c2ccco2)c1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL511404 EC50 4.0 nM
CC(C)(C)[C@H](NC(=O)n1c(=O)n(CCC2CCOCC2)c2ccccc21)C(N)=O CHEMBL1162994 Ki 4.0 nM
COc1ccc(F)c(-c2c[nH]c(-c3cccc(CN4CCOCC4)c3)n2)c1 CHEMBL1644734 EC50 4.0 nM
COc1ccc(F)c(-c2c[nH]c(-c3cccc(CN4CCCCC4)c3)n2)c1 CHEMBL1644742 EC50 4.0 nM
O=C(c1cccc2[nH]ncc12)N1CC[C@@](O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765263 IC50 4.0 nM
Cc1cccc2c1CCN2C(=O)C12CC3CC(CC(C3)C1)C2 CHEMBL2338182 EC50 4.0 nM
CCN(CC)c1ccc(CN(c2ncc(C)s2)S(=O)(=O)c2ccc(OC)cc2)cc1 CHEMBL2336549 Ki 4.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nn(-c2ccc(Cl)cc2Cl)c2c1Cc1cc(C3CC3)ccc1-2 CHEMBL3781178 Ki 4.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3ccccc3s2)n1 CHEMBL3669103 IC50 4.0 nM
COc1nc(NCCc2ccc(OC(F)F)cc2)nc(-c2cccc(OC)c2C(C)(C)O)n1 CHEMBL3669105 IC50 4.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(Cl)c(S(=O)(=O)NC3CC3)c2)n1 CHEMBL3669114 IC50 4.0 nM
CNC(=O)[C@@H](NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(C)(C)C CHEMBL4107610 EC50 4.0 nM
Cc1nc([C@@](C)(CC2CC2)NC(=O)c2cnc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1 CHEMBL4111892 EC50 4.0 nM
COc1ccc(/C=C2\C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 CHEMBL123515 Ki 4.07 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(C3CC3)c2n1 CHEMBL2057800 EC50 4.1 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(C3CC3)c2n1 CHEMBL3092897 EC50 4.1 nM
Cc1nc([C@](C)(NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)C2CC2)no1 CHEMBL4113461 EC50 4.1 nM
CC(C)C[C@H](NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(N)=O CHEMBL3952854 EC50 4.1 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3(F)COC3)cn2)no1 CHEMBL3896366 EC50 4.1 nM
CC(C)c1ccc(C(NC(=O)Cc2ccccc2)NC(=O)Cc2ccccc2)cc1 CHEMBL2179763 EC50 4.11 nM
CC[C@@H]1COc2cccc3c(=O)c(C(=O)NC4CCCCCC4)cn1c23 CHEMBL2163577 Ki 4.12 nM
Cc1ccc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4779298 EC50 4.15 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(C)C4CCCCC4)ccc3n2CC2CC2)cc1 CHEMBL453842 EC50 4.2 nM
Cc1c(C(=O)NC2CCCCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C CHEMBL579249 Ki 4.2 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccc(O)cc3)ccc21 CHEMBL1215918 Ki 4.2 nM
CC1(C)CN(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)CCC1CNS(=O)(=O)C(F)(F)F CHEMBL1270193 Ki 4.2 nM
O=C(c1ccccc1)N1CC[C@](O)(c2ccccc2)[C@H]2CCCC[C@H]21 CHEMBL1765159 IC50 4.2 nM
O=C(NC1CCCCCC1)c1cccn(Cc2ccc(Cl)cc2)c1=O CHEMBL3114350 Ki 4.2 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCCC2)no1 CHEMBL3353865 EC50 4.2 nM
CC(C)(NC(=O)c1nn(-c2ccccn2)c2c1C[C@H]1C[C@@H]21)c1ccccc1 CHEMBL3354944 EC50 4.2 nM
CC1(C)Oc2cc([C@]34CC5CC(C[C@@](C#N)(C5)C3)C4)cc(O)c2[C@@H]2C[C@H](O)CC[C@H]21 CHEMBL3416122 Ki 4.2 nM
CC1CCC(NC(=O)c2cc3ccccc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL3422785 Ki 4.2 nM
Cn1nnc(C(NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)C(C)(C)C)n1 CHEMBL3940981 EC50 4.2 nM
CCCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)c1cnoc1-2 CHEMBL4444725 IC50 4.2 nM
CC1(C)Oc2cc(C3(CCCCCCCN=C=S)CCCC3)cc(O)c2[C@@H]2C[C@H](CN=C=S)CC[C@H]21 CHEMBL5080187 Ki 4.2 nM
CCCCn1nc(C(=O)N[C@H](C(N)=O)C(C)C)c2ccccc21 CHEMBL5180182 EC50 4.2 nM
C1=C(CCN2CCOCC2)c2ccccc2/C1=C/c1ccc2c3c(cccc13)CC2 CHEMBL4550629 Ki 4.22 nM
O=S(=O)(CCCC(F)(F)F)Oc1cccc(Oc2cccc3c2C[C@H](CO)C3)c1 CHEMBL1668508 pKi(nM) 4.266 nM
CCCCCn1cc(C(=O)N[C@H](C(=O)OC)C(C)(C)C)c2cccnc21 CHEMBL4474071 pEC50 4.266 nM
CCCc1c(C)sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c1C(=O)OC CHEMBL4441693 Ki 4.28 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2ccc(C(C)C)cc2)cc1 CHEMBL2326300 pKi 4.295 nM
CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(S(=O)(=O)N2CCCC2)c1 CHEMBL256753 EC50 4.3 nM
CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3CCCOC)CC1 CHEMBL3357337 EC50 4.3 nM
CCCCCn1nc2c3ccccc3n(CCCCC)cc-2c1=O CHEMBL3421694 Ki 4.3 nM
CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC CHEMBL3582018 EC50 4.3 nM
CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)nn1CCCC#N CHEMBL3650090 Ki 4.3 nM
Cc1nc(C(CC(C)C)NC(=O)c2ccc(C3CC(F)(F)C3)c(OCC3CC3)n2)no1 CHEMBL3971343 EC50 4.3 nM
CCCc1sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c(C(=O)O[11CH3])c1C CHEMBL4081467 Ki 4.3 nM
CCCCC/C=C\[C@H](C)/C=C\C/C=C\C/C=C\CCCC(=O)NC1CC1 CHEMBL4215369 Ki 4.3 nM
Cc1c(C(=O)/N=c2\cc(C(C)(C)C)n(C)n2CC2CC2)cccc1C(F)(F)F CHEMBL272754 EC50 4.4 nM
C=CCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL1216000 Ki 4.4 nM
C[C@@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccoc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL1270480 Ki 4.4 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(NS(C)(=O)=O)CC1 CHEMBL2018778 Ki 4.4 nM
CCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(Sc3ccccc3)cc21 CHEMBL2152810 Ki 4.4 nM
CCCCCOc1ccccc1-c1cc(C(=O)NC2CCC2)no1 CHEMBL2414031 EC50 4.4 nM
CCC(CC)(NC(=O)c1ccc(N2CC(OC)C2)c(OCC2CC2)n1)C(=O)N1CC(F)C1 CHEMBL3582012 EC50 4.4 nM
C/C(=N\Oc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1)C(F)(F)F CHEMBL3953556 Ki 4.4 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC[C@H](O)C(F)(F)F)n1)C(=O)NC CHEMBL3911075 EC50 4.4 nM
CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)c1noc(N)n1 CHEMBL3942402 EC50 4.4 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cc(-c2ccccc2)nn(C2CCCC2)c1=O CHEMBL4071738 Ki 4.4 nM
COc1ccc(C(=O)c2cn(CC3CCOCC3)c3ccc(O)cc23)cc1 CHEMBL4284943 EC50 4.4 nM
COc1ccc(S(=O)(=O)c2ccc(C(C)NS(C)(=O)=O)cc2)c(S(=O)(=O)c2ccc(O[11CH3])cc2)c1 CHEMBL1081623 Ki 4.5 nM
COc1ccc(S(=O)(=O)c2ccc([C@H](C)NS(C)(=O)=O)cc2)c(S(=O)(=O)c2ccc(O[11CH3])cc2)c1 CHEMBL3093359 Ki 4.5 nM
COCCn1c(-c2ccccc2Cl)nc2c(N3CCN(CCF)CC3)nc(C)nc21 CHEMBL3092891 EC50 4.5 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nc(C(O)c2cccnc2)c2ccccn12 CHEMBL3114534 IC50 4.5 nM
CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CCC23COC3)c(OCC2CC2)n1 CHEMBL3938202 EC50 4.5 nM
O=C(N[C@@H](c1ccccn1)C(F)(F)F)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1 CHEMBL3938697 EC50 4.5 nM
CCCCn1cc(C(=O)c2ccccc2OC)c2ccccc21 CHEMBL4089341 EC50 4.5 nM
CCCCOC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@H](O)C[C@@H]21 CHEMBL4519051 Ki 4.5 nM
CCCCC1(c2cc(O)c3cc(CCC)c(=O)oc3c2)CCCCC1 CHEMBL4847976 EC50 4.51 nM
Cc1c(C(=O)c2ccc3ccccc3c2)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL2381801 Ki 4.56 nM
COc1ccc2c(c1)c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1 CHEMBL272882 Log Ki 4.571 nM
CCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL498346 EC50 4.6 nM
CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)c4ccncc4)ccc32)CC1 CHEMBL1950932 EC50 4.6 nM
CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3C)CC1 CHEMBL2057798 EC50 4.6 nM
O=C(N1CCc2cc(F)ccc21)C12CC3CC(CC(C3)C1)C2 CHEMBL2338183 EC50 4.6 nM
CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3C)CC1 CHEMBL3092905 EC50 4.6 nM
CC1(C)Oc2cc([C@]34CC5CC(C[C@@](CC#N)(C5)C3)C4)cc(O)c2[C@@H]2C[C@H](O)CC[C@H]21 CHEMBL3416126 Ki 4.6 nM
CN1CCC[C@H]1COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686294 Ki 4.6 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@@H]2CCCN2)s1 CHEMBL3686307 Ki 4.6 nM
COC(=O)C(C)(C)NC(=O)c1ccc(N2CCCC2)c(OCC2CC2)n1 CHEMBL3925192 EC50 4.6 nM
CCC(CC)(NC(=O)c1ccc(N2CCC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC CHEMBL3917914 EC50 4.6 nM
CN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C CHEMBL3907722 EC50 4.6 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc([Si](C)(C)CCCCCC)cc1O CHEMBL5204553 Ki 4.66 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2ccccc21 CHEMBL201571 Ki 4.7 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cc(C(C)(C)C)on1 CHEMBL449624 Ki 4.7 nM
CCN1CCN(c2nc(C)nc3[nH]c(-c4ccccc4Cl)nc23)CC1 CHEMBL2057799 EC50 4.7 nM
CC(C)(C)CC(=O)Nc1sc2c(c1C(=O)N1CCC(F)(F)CC1)CCCC2 CHEMBL2204905 EC50 4.7 nM
O=C(Nc1sc2c(c1C(=O)N1CC(F)(F)C1)CCOC2)c1ccccc1OC(F)(F)F CHEMBL2205592 EC50 4.7 nM
CCN1CCN(c2nc(C)nc3[nH]c(-c4ccccc4Cl)nc23)CC1 CHEMBL3092906 EC50 4.7 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2C[C@@H](O)CN2C2CCCCC2)on1 CHEMBL3353878 EC50 4.7 nM
O=C(Nc1nc2cc(Cl)ccc2s1)[C@@H]1CCCN1C1CCOCC1 CHEMBL3353873 EC50 4.7 nM
Cc1cccc(-c2ccc(C(C)(C)c3ccccc3)cc2O)c1 CHEMBL3915185 Ki 4.7 nM
CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 CHEMBL3954460 EC50 4.7 nM
Cc1cc(-c2cc(C(=O)NC3CCCCC3)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl CHEMBL4084087 Ki 4.7 nM
C=CCOc1cc(CCCCC)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL4638147 Ki 4.7 nM
CCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(CO)=C[C@@H]21 CHEMBL4747195 Ki 4.7 nM
CC1(C)Oc2cc(C34CC5CC(CC(CN=C=S)(C5)O3)C4)cc(O)c2[C@@H]2C[C@H](CO)CC[C@H]21 CHEMBL4760082 Ki 4.7 nM
COc1cc(C(=O)c2ccccc2)cc(O)c1-c1cc(Cl)cc(Cl)c1 CHEMBL460754 Ki 4.77 nM
CCCCCOc1cc(/C=C/C(=O)NCCc2ccc(O)cc2)ccc1OC CHEMBL3410833 pKi 4.797 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C(=O)O)cc1-2 CHEMBL111340 Ki 4.8 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4)no3)ccc21 CHEMBL499628 EC50 4.8 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2C[C@@H]2CCCO2)cc1 CHEMBL471558 EC50 4.8 nM
CCCCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC2C4)C3)no1 CHEMBL2414029 EC50 4.8 nM
CC1CCC(NC(=O)c2cccn(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL3114172 Ki 4.8 nM
CN(C)CCn1c(CC(C)(C)C)nc2cc(S(=O)(=O)C3CN(C(N)=O)C3)ccc21 CHEMBL3234675 EC50 4.8 nM
CCCNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Br CHEMBL3696832 IC50 4.8 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCC2(C1)CC2(F)F CHEMBL3915420 EC50 4.8 nM
Cc1nc(C(NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)C(C)(C)C)no1 CHEMBL3943211 EC50 4.8 nM
CCCCCn1c(=O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(O)c2nn(CCO)cc21 CHEMBL4636524 Ki 4.8 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3c(F)c(F)c(F)c(F)c23)C1(C)C CHEMBL409669 Log Ki 4.898 nM
CC(C)(C)c1ncc(OCCCc2nc(-c3ccc(F)cc3Cl)no2)cn1 CHEMBL524826 EC50 4.9 nM
CC(C)(C)CO/C=N/CCCOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686343 Ki 4.9 nM
Cc1cnc(C(C)(C)NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)s1 CHEMBL3946687 EC50 4.9 nM
Cc1nc([C@@](C)(CC2CC2)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1 CHEMBL4113373 EC50 4.9 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCCC12CCC2 CHEMBL3906456 EC50 4.9 nM
Cc1cc(-c2cc(C(=O)NC3CCCCCC3)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl CHEMBL4071007 Ki 4.9 nM
CCCCCn1cc(C(=O)c2ccc3c(c2)CC(C)(C)C3)c2ccccc21 CHEMBL4856192 Ki 4.9 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccco3)cc12 CHEMBL2381674 Ki 4.92 nM
CC[C@@H]1COc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163579 Ki 4.93 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(C(C)(C)C)cc12 CHEMBL2381812 Ki 4.95 nM
CC(C)c1cc(NCCO)nnc1C(=O)NC1C2CC3CC(C2)CC1C3 CHEMBL4127553 EC50 4.955 nM
CCCCCn1c(C)c(C(=O)NC2C(C)(C)[C@@H]3CC[C@@]2(C)C3)c2cccc(OC)c21 CHEMBL2112289 Ki 5.0 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc2c1CCC2 CHEMBL234175 Ki 5.0 nM
C=CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)C2 CHEMBL250026 EC50 5.0 nM
Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCOCC1 CHEMBL253074 EC50 5.0 nM
Cc1ccc(C(=O)N[C@@H](C)C2CCCCC2)cc1S(=O)(=O)N1CCCCC1 CHEMBL404647 EC50 5.0 nM
Cc1ccc(C(=O)Nc2ccccc2Cl)cc1S(=O)(=O)N1CCCCC1 CHEMBL402768 EC50 5.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(C#N)ccc23)C1(C)C CHEMBL410655 Ki 5.0 nM
CCOc1ccc(Cc2nc3cc(S(=O)(=O)CC)c(Cl)cc3n2CC2CCCCC2)cc1 CHEMBL256993 EC50 5.0 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3ccc(CN)cc3)ccc2n1CC1CCOCC1 CHEMBL259321 EC50 5.0 nM
Cc1ccc(-c2cncc(NC(=O)C(C)(C)S(=O)(=O)c3ccc(Cl)cc3)c2)s1 CHEMBL466821 EC50 5.0 nM
CC(C)(C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL466603 EC50 5.0 nM
Cn1nnc([C@@H](NC(=O)n2c(=O)n(CCN3CCOCC3)c3ccccc32)C(C)(C)C)n1 CHEMBL522553 Ki 5.0 nM
CC(C)(C)[C@@H](C#N)NC(=O)n1c(=O)n(CCN2CCOCC2)c2ccccc21 CHEMBL494986 Ki 5.0 nM
CC(C)(C)[C@H](NC(=O)n1c(=O)n(CCN2CCOCC2)c2ccccc21)C(N)=O CHEMBL523050 Ki 5.0 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2Cc2ccncc2)cc1 CHEMBL512906 EC50 5.0 nM
Cn1ccc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c21 CHEMBL567292 EC50 5.0 nM
O=S(=O)(c1ccccn1)c1ccc(C(F)(F)F)cc1S(=O)(=O)N1CCC2(CC1)CC2NS(=O)(=O)C(F)(F)F CHEMBL596135 Ki 5.0 nM
CCCCCn1cc(C(=O)N[C@H]2C(C)(C)[C@H]3CC[C@]2(C)C3)c(=O)c2cc(Br)ccc21 CHEMBL1215991 Ki 5.0 nM
FC1(F)CCN(Cc2cccc(-c3nc(-c4cccc(C(F)(F)F)c4)c[nH]3)c2)CC1 CHEMBL1644683 EC50 5.0 nM
Brc1cccc(-c2c[nH]c(-c3cccc(CN4CCOCC4)c3)n2)c1 CHEMBL1644687 EC50 5.0 nM
FC1CCN(Cc2cccc(-c3nc(-c4cccc(Cl)c4Cl)c[nH]3)c2)CC1 CHEMBL1644691 EC50 5.0 nM
COc1ccc(F)c(-c2c[nH]c(-c3cccc(CN4CCC(F)(F)CC4)c3)n2)c1 CHEMBL1644735 EC50 5.0 nM
COc1ccc(F)c(-c2c[nH]c(-c3cccc(CN4CCC(F)CC4)c3)n2)c1 CHEMBL1644736 EC50 5.0 nM
O=C(c1cccc(Cl)c1Cl)c1nc(CN2CCOCC2)c2ccccn12 CHEMBL1760930 IC50 5.0 nM
CC(C)(C)c1cc(NC(=O)N2CCCN(c3ncc(C(F)(F)F)cc3Cl)CC2)no1 CHEMBL1800691 EC50 5.0 nM
CC(C)(C)c1cc(NC(=O)N2CCCN(c3ccc(C(F)(F)F)cn3)CC2)no1 CHEMBL1800745 EC50 5.0 nM
COc1ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c2c1OC CHEMBL1822929 Ki 5.0 nM
CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3C(COC)COC)CC1 CHEMBL3357338 EC50 5.0 nM
O=C(Nc1cc(C(F)(F)F)on1)N1CCCN(C(=O)c2ccc(C(F)(F)F)cn2)CC1 CHEMBL3400948 EC50 5.0 nM
CC(C)Cn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1OCC1CCOC1 CHEMBL3647307 Ki 5.0 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OCc2cnccn2)s1 CHEMBL3686290 Ki 5.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3ccccc3o2)n1 CHEMBL3669087 IC50 5.0 nM
CNC(=O)[C@@H](NC(=O)c1ccc(Br)c(OCC2CCCO2)n1)C(C)(C)C CHEMBL4109758 EC50 5.0 nM
O=C(N[C@@H](c1cccnc1)C(F)(F)F)c1cc(OCc2ccc(F)cc2)c(Cl)cn1 CHEMBL3940187 EC50 5.0 nM
CCCCCn1cc(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2cccnc21 CHEMBL4476642 EC50 5.0 nM
CCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL5188087 Ki 5.01 nM
CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(Cl)cc3)c(=O)[nH]c12 CHEMBL203924 Log IC50 5.012 nM
CCCCc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)nc(C)n1-c1ccccc1 CHEMBL597438 pEC50 5.012 nM
COC(=O)c1c(NC(=O)C23CC4CC(CC(C4)C2)C3)sc2c1CCCC2 CHEMBL4471470 Ki 5.08 nM
Cc1noc(C)c1S(=O)(=O)N1CCc2c(nc(C(C)(C)C)n2CC2CC2)C1 CHEMBL562150 EC50 5.1 nM
CC(O)C1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC1 CHEMBL593595 Ki 5.1 nM
CCCCn1cc(Br)cc(C(=O)NC2CCCCCC2)c1=O CHEMBL3114180 Ki 5.1 nM
CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21)c1ccncc1 CHEMBL3354947 EC50 5.1 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1O/N=C(\N)CC CHEMBL3650123 Ki 5.1 nM
CC(C)C[C@H](NC(=O)c1ccc(NC2CC2)c(OCC2CC2)n1)C(N)=O CHEMBL3933346 EC50 5.1 nM
CCC(CC)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)C(=O)NC CHEMBL3917911 EC50 5.1 nM
C[C@H](Oc1cc(C(=O)NC(C(=O)N2CC(F)(F)C2)C(C)(C)C)ncc1C1CC1)C(F)(F)F CHEMBL3957631 EC50 5.1 nM
C[C@H](Oc1cc(C(=O)NC2(CC(N)=O)CS(=O)(=O)C2)ncc1C1(F)CCC1)C(F)(F)F CHEMBL3904362 EC50 5.1 nM
CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC[C@@H](O)C[C@@H]32)CCC1 CHEMBL1259076 Ki 5.13 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1Cl CHEMBL216837 Ki 5.2 nM
Cc1ccc(-c2nc(CC(C)(C)C)cs2)cc1S(=O)(=O)N1CCOCC1 CHEMBL474897 Ki 5.2 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)NCCO CHEMBL3914196 EC50 5.2 nM
CC1(C)COCCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3965037 EC50 5.2 nM
CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(CC)cc12 CHEMBL2381808 Ki 5.22 nM
CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)c2ccc(Cl)cc21 CHEMBL235733 Ki 5.3 nM
CCCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1 CHEMBL566057 Ki 5.3 nM
CCCCCCC(C)(C)c1cc(C#N)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL600801 Ki 5.3 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CCOC(F)(F)F CHEMBL1800179 EC50 5.3 nM
COCCn1c(-c2ccccc2Cl)nc2c(N3CCN4C(=O)CCC4C3)nc(C)nc21 CHEMBL3092893 Ki 5.3 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1O/N=C(\N)C(C)C CHEMBL3650112 Ki 5.3 nM
COCCN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C CHEMBL3941576 EC50 5.3 nM
Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(Cl)cn2)no1 CHEMBL3942094 EC50 5.3 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1cnoc1-2 CHEMBL4585657 Ki 5.3 nM
Cc1ccc(Cn2nc(/C=C/[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL2420248 EC50 5.32 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL2326298 pKi 5.395 nM
CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC1 CHEMBL595481 Ki 5.4 nM
CCCCCCC1CCCc2c1cc1c(c2O)[C@@H]2CC(C)=CC[C@H]2C(C)(C)O1 CHEMBL303479 Ki 5.4 nM
CCCCCn1cc(C(=O)c2cccc3cccc(Br)c23)c2ccccc21 CHEMBL2206846 Ki 5.4 nM
CC(C)(C)CC(=O)Nc1sc2c(c1C(=O)N1CC(F)(F)C1)CCCC2 CHEMBL2204902 EC50 5.4 nM
CC(NC(=O)c1nc(N2CCOCC2)n2ccccc12)C(C)(C)C CHEMBL3234677 EC50 5.4 nM
O=C(N[C@@H](CO)c1ccccc1)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21 CHEMBL3354957 EC50 5.4 nM
CCCCCn1cc2c(=O)n(CCC3CCCCC3)nc-2c2ccccc21 CHEMBL3421698 EC50 5.4 nM
CCCNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Cl CHEMBL3696824 IC50 5.4 nM
CC(C)(C)/C(COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1)=N\O CHEMBL3686322 Ki 5.4 nM
CCCCn1/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)sc2ccncc21 CHEMBL3647320 Ki 5.4 nM
CC(C)CC(C)(CO)NC(=O)c1ccc(C2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3946389 EC50 5.4 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)C(=O)N2CCC2)no1 CHEMBL3958413 EC50 5.4 nM
CC(C)(C)C(CO)NC(=O)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL3900220 EC50 5.4 nM
COc1ccc(C(=O)c2cn(CCN3CCOCC3)c3ccc(O)cc23)cc1 CHEMBL4277575 EC50 5.4 nM
CCCCCCC1(c2ccc(-c3cc(C)cc(C)c3)c(O)c2)CCCC1 CHEMBL233634 Ki 5.5 nM
Cc1ccc2c(=O)c(C(=O)NC3CCCCC3)cn(Cc3ccc(F)cc3)c2n1 CHEMBL497304 Ki 5.5 nM
O=S(=O)(c1ccccc1F)c1cc(Cl)ccc1S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL603321 Ki 5.5 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1C CHEMBL1641936 EC50 5.5 nM
O=C(c1ccc2cnccc2n1)N1CC[C@@](O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765260 IC50 5.5 nM
COCCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152806 Ki 5.5 nM
CCN(CC)c1ccc(CN(c2ccccc2)S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL2336538 Ki 5.5 nM
CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2[C@@H]2C[C@H](C=O)CC[C@H]21 CHEMBL2348459 Ki 5.5 nM
CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21)c1cccnc1 CHEMBL3354948 EC50 5.5 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OCc2nccs2)s1 CHEMBL3686302 Ki 5.5 nM
Cc1nc(C(C)(NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3(F)COC3)cn2)C2CC2)no1 CHEMBL3978186 EC50 5.5 nM
CCCCCn1nc(C(=O)NC(C)(C)CO)c(N)c1C(C)(C)C CHEMBL4791274 EC50 5.5 nM
CCCCCn1c(C)c(C(=O)c2cccc3ccc(CC)cc23)c2ccccc21 CHEMBL562489 pKi 5.598 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL2326295 pKi 5.598 nM
COC(=O)CCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(O)c1 CHEMBL234014 Ki 5.6 nM
COCCn1c(C)c(C(C)(C)C)s/c1=N\C(=O)c1cccc(C(F)(F)F)c1 CHEMBL248014 EC50 5.6 nM
Cc1ccc(C(=O)NC2C3CC4CC(C3)CC2C4)cc1S(=O)(=O)N1CCOCC1 CHEMBL256110 Ki 5.6 nM
CC(=O)NCCCCCc1cc(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)ccn1 CHEMBL1950834 EC50 5.6 nM
CC(C)C[C@H](C#N)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL4110682 EC50 5.6 nM
CC1(C)CC(O)CCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3921429 EC50 5.6 nM
Cc1csc(C(C)(C)NC(=O)c2cnc(N3CC(F)(F)C3)c(OCC3CC3)n2)n1 CHEMBL3957074 EC50 5.6 nM
NC(=O)C(CC1CCC1)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3978729 EC50 5.6 nM
O=C(NC1(CO)CCCC1)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL4161266 EC50 5.6 nM
C=CCc1ccc(O)c(-c2ccc(O)c(CC=C)c2)c1 CHEMBL16901 Ki 5.61 nM
CC(C)(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 CHEMBL3959623 Ki 5.69 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2cccc(OC(F)(F)F)c2)n1CC1CC1 CHEMBL247651 IC50 5.7 nM
CCOc1ccc(Cc2nc3cc(N(C)C(=O)NC(C)C)ccc3n2CC2CC2)cc1 CHEMBL462533 Ki 5.7 nM
Cc1ccc(-c2nc(C(C)(C)C)cs2)cc1S(=O)(=O)N1CCOCC1 CHEMBL475093 Ki 5.7 nM
Cc1c(C(=O)NC(C)c2ccccc2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C CHEMBL574270 Ki 5.7 nM
CCC(C)(C)NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-n2cccc2)c1C CHEMBL1629731 Ki 5.7 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2ccc(OC(F)(F)F)cc2)n1CC1CC1 CHEMBL1668506 Ki 5.7 nM
Cc1ccc(Cn2cc(C(=O)N[C@@H]3C(C)(C)C4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL3613097 Ki 5.7 nM
CC(C)C[C@H](NC(=O)c1ccc(C2CCOC2)c(OCC2CC2)n1)C(N)=O CHEMBL3939087 EC50 5.7 nM
Cc1nc(C(C)(NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C2CC2)no1 CHEMBL3925709 EC50 5.7 nM
O=C(N[C@@H](c1cccnc1)C(F)(F)F)c1cc(OCC2CC2)c(Cl)cn1 CHEMBL3919727 EC50 5.7 nM
C[C@H]1CC[C@@H](NC(=O)c2cc(-c3ccccc3)nn(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL4094388 Ki 5.7 nM
CCCOc1cccc2c(C(=O)c3ccc(OC)cc3)cn(CC3CCOCC3)c12 CHEMBL4294558 Ki 5.7 nM
Cc1c(F)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4760014 Ki 5.7 nM
Cc1c(-c2ccccc2)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4782654 Ki 5.7 nM
CC(C)c1cc(NC2CCCC2)nnc1C(=O)NC1C2CC3CC(C2)CC1C3 CHEMBL4129072 EC50 5.701 nM
C=CCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccco3)ccc21 CHEMBL2087106 Ki 5.73 nM
CCN(CC)c1ccc(C(NC(=O)Cc2ccccc2)NC(=O)Cc2ccccc2)cc1 CHEMBL2179771 EC50 5.73 nM
CCN(CC)c1ccc(CN(c2ccc(C)cc2)S(=O)(=O)c2cccc(C)c2)cc1 CHEMBL2326299 pKi 5.794 nM
CCCCCN1C(=O)/C(=N\NC(=O)c2ccccc2)c2ccc(OC)cc21 CHEMBL523084 EC50 5.8 nM
CSC(=O)N1CC2(CCCCC2)CO/C1=N\c1cccc2ccccc12 CHEMBL475610 Ki 5.8 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(Cl)c2c1CCCC2 CHEMBL480579 Ki 5.8 nM
C[C@H]1CC[C@@H](NC(=O)c2cc3cccnc3n(Cc3ccccc3)c2=O)CC1 CHEMBL467681 Ki 5.8 nM
CC1(C)C(C(=O)c2cn(CCN3CCCC3)c3ccccc23)C1(C)C CHEMBL568807 Ki 5.8 nM
CCCCCn1cc(C(=O)NCC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)cc1-c1ccccc1 CHEMBL1641943 EC50 5.8 nM
O=C(CCc1nc(-c2ccc(F)cc2Br)no1)Nc1ccc2c(c1)c1ccccc1n2CCF CHEMBL3093378 Ki 5.8 nM
CCOC(=O)CN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C CHEMBL3953077 EC50 5.8 nM
NC(=O)CC1(NC(=O)c2cnc(N3CC(F)(F)C3)c(OCC3CC3)n2)COC1 CHEMBL3935206 EC50 5.8 nM
CC(C)[C@](C)(CO)NC(=O)c1cc(Cc2ccc(F)cc2)c(Cl)cn1 CHEMBL3890458 EC50 5.8 nM
CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)c1nccs1 CHEMBL3932973 EC50 5.8 nM
CC1(C)Oc2cc(C3(CCCCCBr)CCC3)cc(O)c2[C@@H]2CC(=O)CC[C@H]21 CHEMBL1259057 Ki 5.88 nM
O=C(c1cn(CC2CCOCC2)c2ccccc12)C12CC3CC(CC(C3)O1)C2 CHEMBL569992 pKi 5.888 nM
O=C(Cn1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2Cl)n1)N1CCCCC1 CHEMBL481886 IC50 5.9 nM
CN1CCC(C(=O)N2CC[C@](O)(c3ccccc3)[C@H]3CCCC[C@H]32)C1 CHEMBL1765248 IC50 5.9 nM
COCCNC(=O)c1c(NC(=O)CC(C)(C)C)sc2c1C(C)(C)CC2 CHEMBL2205581 EC50 5.9 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C3CN(C(N)=O)C3)ccc2n1CCOC(F)(F)F CHEMBL3357385 EC50 5.9 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(CC(C)(C)O)c2n1 CHEMBL3357342 EC50 5.9 nM
Cc1nc(C(C)(CC(C)(C)C)NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)no1 CHEMBL3914194 EC50 5.9 nM
O=C(NC1(C(F)(F)F)CC1)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL4175548 EC50 5.9 nM
Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)n1C[C@H]1CCCO1 CHEMBL4761606 Ki 5.9 nM
CCc1sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c(C(=O)OC)c1C CHEMBL4476681 Ki 5.92 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCC(F)(F)F)c(C3CC3)cn2)no1 CHEMBL3904968 EC50 5.95 nM
CCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL338455 Ki 6.0 nM
COc1ccc(S(=O)(=O)c2cc(OC)ccc2S(=O)(=O)c2ccc(C(C)(C)NS(C)(=O)=O)cc2)cc1 CHEMBL198252 Ki 6.0 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2Cl)cc1 CHEMBL198253 Ki 6.0 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1cccc2ccccc12 CHEMBL232328 Ki 6.0 nM
CSC(=S)N1CC2(CCCCC2)CS/C1=N\c1ccc(OC(F)(F)F)cc1 CHEMBL232129 Ki 6.0 nM
Cc1ccc(C(=O)N2CCCC3CCCCC32)cc1S(=O)(=O)N1CCCCC1 CHEMBL253265 EC50 6.0 nM
Cc1ccc(C(=O)Nc2ccccc2S(C)(=O)=O)cc1S(=O)(=O)N1CCCCC1 CHEMBL253463 EC50 6.0 nM
CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccccc4Cl)no3)ccc21 CHEMBL499626 EC50 6.0 nM
Clc1cccc(-c2ccc(CN3CCO[C@@H](c4ccccc4)C3)cc2)c1Cl CHEMBL494994 EC50 6.0 nM
CC(C)(C)[C@H](NC(=O)n1c(=O)n(CC2CCCO2)c2ccccc21)C(N)=O CHEMBL496497 Ki 6.0 nM
FC(F)(F)c1cccc(-c2c[nH]c(-c3cccc(CN4CCSCC4)c3)n2)c1 CHEMBL1644676 EC50 6.0 nM
CC(C)(C)c1ccc2oc(N3CCCN(C(=O)N4CCOCC4)CC3)nc2c1 CHEMBL1800752 EC50 6.0 nM
CC(C)(C)c1ccc2oc(N3CCCN(C(=O)N4CCS(=O)(=O)CC4)CC3)nc2c1 CHEMBL1800753 EC50 6.0 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NCC(N)=O CHEMBL2016599 Ki 6.0 nM
CC1OCc2sc(NC(=O)CC(C)(C)C)c(C(=O)N3CC(F)(F)C3)c21 CHEMBL2204892 EC50 6.0 nM
CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OCc2ccccc2)s1 CHEMBL3686300 Ki 6.0 nM
CC1(C)C2CC[C@@](C)(C2)C1NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1Cc1cc(C3CC3)ccc1-2 CHEMBL3781131 Ki 6.0 nM
CC(C)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1nccs1 CHEMBL3896458 EC50 6.0 nM
CCCCCCC(C)(C)c1cc(OC)c(C2=C[C@H]3CC[C@]2(CO)C3(C)C)c(OC)c1 CHEMBL3921607 Ki 6.0 nM
COc1cc(Nc2ccc(S(=O)(=O)NCC3CC3)cc2)cc(OC)c1 CHEMBL3912856 Ki 6.0 nM
CCCn1cc(C(=O)c2ccc(C)c3ccccc23)c2ccccc21 CHEMBL497811 pKi 6.095 nM
CSC(=S)N1CC(C)(C)CS/C1=N\c1ccccc1C(C)C CHEMBL232730 IC50 6.1 nM
Cc1cccc(C(=O)N2CC[C@@](O)(c3ccccc3)[C@@H]3CCCC[C@@H]32)n1 CHEMBL1765267 IC50 6.1 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCC(=O)N2c2ccc(Cl)cc2)on1 CHEMBL3353880 EC50 6.1 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCC(=O)N2c2ccc(Cl)cc2)no1 CHEMBL3354536 EC50 6.1 nM
CCCCn1nc(C(C)(C)C)s/c1=N/C(=O)c1cc(C(F)(F)F)ccc1O/N=C(\CC)C(=O)ON CHEMBL3650113 Ki 6.1 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(N3CC(F)(F)C3)cn2)C2CC2)no1 CHEMBL3890455 EC50 6.1 nM
CCCC(C)O/N=C(/C)c1cc(O)c2c(c1)OC(C)(C)[C@H]1CC=C(C)C[C@H]21 CHEMBL4238778 Ki 6.1 nM
CCc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)cc(C)n1-c1ccccc1 CHEMBL3962080 Ki 6.15 nM
CCOc1ccc(Cc2nc3cc(C(=O)N4CCCC4)ccc3n2CC2CC2)cc1 CHEMBL454864 EC50 6.2 nM
CC(=O)N1CCC(S(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)CC1 CHEMBL3357370 EC50 6.2 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1/N=N/C(C)(C)C CHEMBL3650087 Ki 6.2 nM
CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)nn1CCCCF CHEMBL3650111 Ki 6.2 nM
CC(C)(C)[C@@H](CO)NC(=O)c1nn(-c2c[n+]([O-])ccn2)c2c1C[C@@H]1C[C@H]21 CHEMBL4175981 EC50 6.2 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCOc3ccccc3)cc1OC2(C)C CHEMBL4249729 Ki 6.2 nM
Cn1cc2c(n1)c(O)c(C(=O)NC13CC4CC(CC(O)(C4)C1)C3)c(=O)n2CCCCF CHEMBL4641997 Ki 6.2 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccccc3Cl)cc12 CHEMBL2381794 Ki 6.21 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3cccs3)cc12 CHEMBL2381778 Ki 6.24 nM
CCOc1ccccc1/N=C1\SCC2(CCCCC2)CN1C(=S)SC CHEMBL232130 Ki 6.3 nM
CCOc1ccc(Cc2nc3cc([S+]([O-])CC)c(Cl)cc3n2CC2CCCCC2)cc1 CHEMBL256992 EC50 6.3 nM
Cc1ccc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL442447 Ki 6.3 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(C(C)C)ccc21 CHEMBL502276 Ki 6.3 nM
CCCCCC1=NN(C(=O)NC2C3CC4CC(C3)CC2C4)CC1c1ccccc1 CHEMBL1224630 Ki 6.3 nM
O=C(c1ccncc1F)N1CC[C@@](O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 CHEMBL1765265 IC50 6.3 nM
CCCCOC(=O)[C@@H](C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL3104358 Ki 6.3 nM
O=C(NCC(O)CO)c1nc2c(-c3ccccc3)cccc2[nH]1 CHEMBL3114525 EC50 6.3 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C3CCN(C(N)=O)CC3)ccc2n1CC1CC1 CHEMBL3357371 EC50 6.3 nM
Clc1cccc(-c2ccc(N3CCCCC3)nn2)c1Cl CHEMBL594281 pEC50 6.31 nM
Cc1nc(C(=O)NC2C3CC4CC(C3)CC2C4)c(C)n1-c1ccccc1 CHEMBL604307 pEC50 6.31 nM
CSc1c(C(=O)NC23CC4CC(CC(C4)C2)C3)nc(C)n1-c1ccccc1 CHEMBL596671 pEC50 6.31 nM
CCc1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)cn1-c1ccccc1 CHEMBL604120 pEC50 6.31 nM
CN(CC(N)=O)Cc1nc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)no1 CHEMBL1682272 pKi 6.31 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CCC(=O)CC21 CHEMBL2218896 pKi 6.31 nM
COCCn1cc(C(=O)Nc2cccc3ccccc23)c2ccccc21 CHEMBL1828807 pEC50 6.31 nM
CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(-c3ccc(Cl)cc3)cc12 CHEMBL2381796 Ki 6.31 nM
O=C(NC1CCCCCC1)c1cccn(Cc2ccc(F)cc2)c1=O CHEMBL2022698 pEC50 6.31 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3cccs3)ccc21 CHEMBL2087109 Ki 6.37 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1 CHEMBL385940 Ki 6.4 nM
O=C(NC1CCCCCC1)c1cn(Cc2ccccc2)c2ccccc2c1=O CHEMBL250768 Ki 6.4 nM
CCCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL57367 Ki 6.4 nM
CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C CHEMBL2170544 Ki 6.4 nM
CC(C)(C)CC(=O)Nc1sc2c(c1C(=O)NCC1CC1)C(C)(C)CC2 CHEMBL2205580 EC50 6.4 nM
O=C(NC1(C(F)(F)F)CC1)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3959114 EC50 6.4 nM
Cc1c(-c2ccc(F)cc2)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1 CHEMBL4757488 EC50 6.45 nM
COC(=O)c1cc(-c2ccccc2)sc1NC(=O)C12CC3CC(CC(C3)C1)C2 CHEMBL4557732 Ki 6.48 nM
CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 CHEMBL1641940 EC50 6.5 nM
CCCCCn1c(C)c(C(=O)c2ccc(CCCC)c3ccc(C)cc23)c2ccccc21 CHEMBL1668395 Ki 6.5 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)Cc3ccccc3)ccc2n1CC1CC1 CHEMBL1800167 EC50 6.5 nM
CC1(C)C2CC[C@](C)(C2)[C@@H]1NC(=O)c1cn(CCCCSc2ccccc2)c2cc(Sc3ccccc3)ccc2c1=O CHEMBL2152817 Ki 6.5 nM
O=C(Nc1sc2c(c1C(=O)N1CC(F)(F)C1)CCOC2)c1c(F)cccc1C(F)(F)F CHEMBL2205593 EC50 6.5 nM
CC(C)[C@H](CC(N)=O)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3973752 EC50 6.5 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(N3CCC(F)(F)C3)cn2)C2CC2)no1 CHEMBL3936627 EC50 6.5 nM
Cc1nc(C(NC(=O)c2cc(O[C@@H](C)C(F)(F)F)c(C3CC3)cn2)C2(C)COC2)no1 CHEMBL3975079 EC50 6.5 nM
CCCCCn1cc(-c2nnc(C34CC5CC(CC(C5)C3)C4)o2)c(=O)c2cc(-c3ccco3)ccc21 CHEMBL4745169 Ki 6.5 nM
CCCCCn1c(C)c(C(=O)c2ccc(CCCC)c3ccccc23)c2ccccc21 CHEMBL540248 pKi 6.501 nM
CCCCCC[Si](C)(C)c1cc(O)c(C2CCCCCC2)c(O)c1 CHEMBL5204014 Ki 6.53 nM
CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(-c3ccco3)cc12 CHEMBL2381673 Ki 6.57 nM
CCCCCCC(C)(C)c1ccc(-c2cc(C)ccc2C)c(O)c1 CHEMBL232411 Ki 6.6 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(Br)cc23)C1(C)C CHEMBL259463 Ki 6.6 nM
CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(S(=O)(=O)N2CCCCC2)c1 CHEMBL256752 EC50 6.6 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1ccc(N(C)C)c2ccccc12 CHEMBL481716 Ki 6.6 nM
Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(S(=O)(=O)N2CCOCC2)c1C CHEMBL593625 Ki 6.6 nM
CCCn1cc(C(=O)c2ccc(I)c3ccccc23)c2ccccc21 CHEMBL2206836 Ki 6.6 nM
O=C(NCC12CC3CC(CC(C3)C1)C2)c1nn(C2CCCCC2)c2c1CCCCCC2 CHEMBL3234685 EC50 6.6 nM
CC(C)C[C@H](NC(=O)c1ccc(C2CCCO2)c(OCC2CC2)n1)C(N)=O CHEMBL3968015 EC50 6.6 nM
CC1(C)CC(C(N)=O)N(C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C1 CHEMBL3905334 EC50 6.6 nM
O=C(NC1(C(=O)O)CCCCC1)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2 CHEMBL2019081 pKi 6.699 nM
C[C@H](NS(C)(=O)=O)c1ccc(Cc2ccc(Cl)cc2S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL198304 Ki 6.7 nM
CCCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)C2 CHEMBL250491 EC50 6.7 nM
CCCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1ONC(C)(C)C CHEMBL3647322 Ki 6.7 nM
O=C(NC(c1ccccn1)C(F)(F)F)c1cc(OCC2CC2)c(C2CC2)cn1 CHEMBL3982907 EC50 6.7 nM
CCCCCc1cc(OCC)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL4640400 Ki 6.7 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)oc(=O)c1ccc(OC)cc12 CHEMBL266712 Ki 6.7 nM
CCCCn1nc(C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c2ccccc21 CHEMBL5184576 pEC50 6.761 nM
CCC1COc2c(OC)ccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163948 Ki 6.78 nM
CSC(=S)N1CC2(CCCCC2)CO/C1=N\c1cccc2nonc12 CHEMBL469896 Ki 6.8 nM
CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3CCOC)CC1 CHEMBL3092908 EC50 6.8 nM
Cc1c2n(c(=O)c3cc(OC(=O)C(C)(C)C)cc(OC(=O)C(C)(C)C)c13)CCCC2 CHEMBL3234708 Ki 6.8 nM
CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3CCOC)CC1 CHEMBL3139138 EC50 6.8 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccc(C)cc3)nc12 CHEMBL3774919 Ki 6.8 nM
Cc1nc([C@@H](NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)C2CC2)no1 CHEMBL3944719 EC50 6.8 nM
CC1(C)C[C@@H]2C[C@@](C)(CN2C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C1 CHEMBL4110534 EC50 6.8 nM
CNC(=O)[C@@H](NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(C)(C)C CHEMBL4109469 EC50 6.8 nM
CCCCC/C=C\[C@H](C)/C=C\C/C=C\C/C=C\CCCC(=O)NC1CCC1 CHEMBL4206063 Ki 6.8 nM
C=CCNC(=O)CCCCCCCCCCOc1cc(CCCCC)cc(OC)c1 CHEMBL4638446 Ki 6.8 nM
CCCCCn1c(C)c(Br)c(C(=O)c2cccc3ccccc23)c1C CHEMBL5282889 EC50 6.8 nM
CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCSC2)c1 CHEMBL602128 Ki 6.9 nM
CCC1COc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL1814463 Ki 6.9 nM
CCC(CC)(NC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1)C(=O)NC CHEMBL3906134 EC50 6.9 nM
CC(C)(C)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3941719 EC50 6.9 nM
CCCCCn1cc(C(=O)c2ccccc2OC)c2ccccc21 CHEMBL4069848 EC50 6.9 nM
Cc1c(-c2ccccc2)cn(Cc2ccc(F)cc2)c(=O)c1C(=O)NC1CCCCCC1 CHEMBL4167303 Ki 6.9 nM
CCCCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL5171161 Ki 6.9 nM
CCCCCn1cc(C(=O)c2cccc3ccc(OC)cc23)c2ccccc21 CHEMBL552088 pKi 6.902 nM
CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)c2c(C)csc21 CHEMBL2316283 Ki 6.95 nM
CCCCCn1cc(C(=O)Cc2ccccc2Cl)c2ccccc21 CHEMBL189035 Ki 7.0 nM
CCCc1ccc(/N=C2\SCC3(CCCCC3)CN2C(=S)SC)cc1 CHEMBL231934 Ki 7.0 nM
Fc1ccc(-c2noc(C3CCN(c4cnc5ccc(Cl)cc5c4)CC3)n2)c(Cl)c1 CHEMBL468176 EC50 7.0 nM
Cc1noc(C)c1S(=O)(=O)N1CCc2c(nc(CC(C)(C)C)n2CC2CC2)C1 CHEMBL558536 EC50 7.0 nM
CCC1(C(=O)Nc2cc(CN3CCOCC3)c(C)cn2)CCCCC1 CHEMBL567942 Ki 7.0 nM
C[C@H]1CN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC[C@@H]1CNS(=O)(=O)C(F)(F)F CHEMBL595460 Ki 7.0 nM
O=C(NC(C1CC1)C1CC1)c1nc(C2CC2)n2ccccc12 CHEMBL1760936 IC50 7.0 nM
CCCCn1c2c(cc(C(=O)NC3(C(=O)O)CCCCC3)c1=O)CCCCCC2 CHEMBL2019083 IC50 7.0 nM
O=C(C1C2CC3CC(C2)CC1C3)N1CCc2ccccc21 CHEMBL2338188 EC50 7.0 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2C[C@@H](O)CN2CC2CCOCC2)on1 CHEMBL3353877 EC50 7.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3c(Cl)cccc3[nH]2)n1 CHEMBL3669054 IC50 7.0 nM
NC(=O)[C@H](CC1CC1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3974280 EC50 7.0 nM
CCCC/C=C\C1(c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CCC(=O)C[C@@H]32)CCCC1 CHEMBL1259243 Ki 7.02 nM
CCCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1 CHEMBL374982 Ki 7.1 nM
CCCCCN1N=C(C(=O)NC2C3CC4CC(C3)CC2C4)CC1c1ccccc1 CHEMBL1223776 Ki 7.1 nM
CC(C)(CCN1CCOCC1)NC(=O)c1ccc(N2CCCC2)c(OCC2CC2)n1 CHEMBL3929186 EC50 7.1 nM
COC(=O)[C@H](CC1CC1)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3973630 EC50 7.1 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(CC(=O)OCCCCBr)cc1OC2(C)C CHEMBL4071457 Ki 7.1 nM
CCCCCn1cc(C(=O)c2ccc(CCCC)c3ccccc23)c2ccccc21 CHEMBL558474 pKi 7.194 nM
CCCCCn1cc(C(=O)c2c(OC)ccc3ccccc23)c2ccccc21 CHEMBL564543 pKi 7.194 nM
Cc1c(C(C)(C)C)s/c(=N\S(=O)(=O)c2cccc3ccccc23)n1CC1CC1 CHEMBL236374 EC50 7.2 nM
CCCCCn1cc(C(=O)c2cc3ccccc3cc2OC)c2ccccc21 CHEMBL498767 Ki 7.2 nM
CC(C)(C)NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C[C@@H]1C[C@H]21 CHEMBL3354962 EC50 7.2 nM
Cc1ccc(Cn2nc(C(=O)N[C@@H]3CC4CC[C@@]3(C)C4(C)C)cc2-c2ccc(Cl)c(C)c2)cc1 CHEMBL3613117 Ki 7.2 nM
CCC(CC)(NC(=O)c1ccc(N(CC(F)(F)F)CC(F)(F)F)c(OCC2CC2)n1)C(=O)NC CHEMBL3984121 EC50 7.2 nM
CN(C(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(C)(C)C CHEMBL3979953 EC50 7.2 nM
NC(=O)[C@@H]1CS(=O)(=O)CN1C(=O)c1ccc(C2CC2)c(OCC2CC2)n1 CHEMBL3914591 EC50 7.2 nM
CCCCCn1nc(C(=O)N[C@H](C(=O)OC)C(C)C)cc1C(C)(C)C CHEMBL4786828 EC50 7.2 nM
CCCc1cc(C(=O)OC)c(NC(=O)C23CC4CC(CC(C4)C2)C3)s1 CHEMBL4545068 Ki 7.21 nM
CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(C(C)(C)C)cc12 CHEMBL2381811 Ki 7.22 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc([Si](C)(C)CCCC)cc1O CHEMBL5192105 Ki 7.25 nM
CCCCCOc1c(OC)ccc2c1C(=O)N(CCc1ccc(O)cc1)C2=O CHEMBL3410824 pKi 7.295 nM
Cc1c(C(C)(C)C)s/c(=N\C(=O)c2cc(C(F)(F)F)ccc2N(C)C)n1CC1CC1 CHEMBL248387 EC50 7.3 nM
CCN(CC)C(=O)c1ccc2c(c1)nc(Cc1ccc(OC)cc1)n2CCC(C)C CHEMBL487629 EC50 7.3 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(C3CCCCC3)ccc21 CHEMBL1215964 Ki 7.3 nM
Cc1ccc(C(=O)N2CC[C@@](O)(c3ccccc3)[C@@H]3CCCC[C@@H]32)cn1 CHEMBL1765276 IC50 7.3 nM
CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)NNS(C)(=O)=O CHEMBL2018781 Ki 7.3 nM
CCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152800 Ki 7.3 nM
CS(=O)(=O)NCCCn1c2ccccc2c2cc(C(=O)N3CCCCC3)ccc21 CHEMBL2441464 EC50 7.3 nM
CC1(C)COCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3922265 EC50 7.3 nM
O=C(NC(CO)CC1CCC1)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3899901 EC50 7.3 nM
CC/C=C\C/C=C\C/C=C\CC1OC1C/C=C\C/C=C\CCC(=O)NCCCO CHEMBL4172580 EC50 7.3 nM
CCC1COc2c(F)ccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163946 Ki 7.34 nM
C=CCNC(=O)CCCCCCCOc1cc(O)cc(C(C)(C)CCCCCC)c1 CHEMBL3323682 Ki 7.36 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(CO)CC21 CHEMBL111099 Ki 7.4 nM
CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 CHEMBL1641944 EC50 7.4 nM
CC(C)(CO)NC(=O)c1nn(-c2cccc(F)c2)c2c1C[C@H]1C[C@@H]21 CHEMBL3354969 EC50 7.4 nM
CC(C)(C)c1cn(C[C@@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2OC[C@H](N)CO)s1 CHEMBL3686298 Ki 7.4 nM
CC(C)Cn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1OCc1ccco1 CHEMBL3647302 Ki 7.4 nM
CN1CC[C@H]1COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686283 Ki 7.4 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCC2(CC2)C1 CHEMBL3956445 EC50 7.4 nM
CCC(CC)(NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC CHEMBL3960115 EC50 7.4 nM
CCCCCn1nc(C(=O)N[C@@H](C(=O)OC)C(C)C)cc1C(C)(C)C CHEMBL4791449 EC50 7.4 nM
CCCCCC[Si](C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21 CHEMBL5200844 Ki 7.41 nM
CC1CCC(NC(=O)c2c(O)c3cccnc3n(CCN3CCOCC3)c2=O)CC1 CHEMBL3422791 Ki 7.44 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)c3cc(C)cc(C)c3)cc1OC2(C)C CHEMBL471296 Ki 7.45 nM
C[C@H](CO)NC(=O)CCC/C=C\C/C=C\CCOc1cccc(C(C)(C)CCCCBr)c1 CHEMBL240314 Ki 7.46 nM
C[C@@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2cc3ccccc3n2S(=O)(=O)c2ccccc2F)cc1 CHEMBL1270388 Ki 7.5 nM
N#C/C(=C\c1cn(CCN2CCCCC2)c2ccccc12)S(=O)(=O)c1ccccc1 CHEMBL1836187 Ki 7.5 nM
CCCCCn1c2ccc(C(=O)N3CCCCC3)cc2c2ccc(OC)cc21 CHEMBL2441475 Ki 7.5 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(C(C)C)c(F)cc21 CHEMBL3782042 Kieq 7.5 nM
CNC(=O)[C@H](CC(C)(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1 CHEMBL3913820 EC50 7.5 nM
Cc1ccc2c(c1)Cc1c(C(=O)NC3CCCCC3)nn(-c3ccc(Cl)cc3Cl)c1-2 CHEMBL216735 pKi(nM) 7.586 nM
Cc1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(C)n1-c1ccccc1 CHEMBL3982062 Ki 7.59 nM
O=S(=O)(c1ccccc1F)c1cc(Cl)ccc1S(=O)(=O)N1CCC(F)(CNS(=O)(=O)C(F)(F)F)CC1 CHEMBL593596 Ki 7.6 nM
CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(=O)N1CC(F)(F)C1 CHEMBL3916573 EC50 7.6 nM
Cc1ccc(-c2cc(C(=O)NC34CC5CC(CC(C5)C3)C4)c(=O)n(C3CCCC3)n2)cc1Cl CHEMBL4086649 Ki 7.6 nM
CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)c4nccs4)ccc32)CC1 CHEMBL1950934 EC50 7.7 nM
CC(=O)N1CCC(CS(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)CC1 CHEMBL3357378 EC50 7.7 nM
CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC2CC2)no1 CHEMBL3353867 EC50 7.7 nM
CCCCCCn1nc2c3ccccc3n(CCCCC)cc-2c1=O CHEMBL3421695 Ki 7.7 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)OCCCCn3ccnc3)cc1OC2(C)C CHEMBL4090703 Ki 7.7 nM
CCCCCCC(C)(C)c1ccc(-c2cccc(OC)c2OC)c(O)c1 CHEMBL427843 Ki 7.8 nM
CC1CCC(NC(=O)c2cc3cccnc3n(Cc3ccccc3)c2=O)CC1 CHEMBL467476 Ki 7.8 nM
CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)cc1C(C)(C)C CHEMBL1641938 EC50 7.8 nM
CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2[C@@H]2C[C@@H](CC=O)CC[C@H]21 CHEMBL2348469 Ki 7.8 nM
CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2c2cccc(O)c2)c(O)c1 CHEMBL5429198 EC50 7.8 nM
CCCc1ccc(C(C)(C)c2cc(O)c3c(c2)OC(C)(C)[C@@H]2CC=C(C)C[C@@H]32)cc1 CHEMBL471122 Ki 7.83 nM
CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCC(=O)NC2CC2)c1 CHEMBL490648 Ki 7.9 nM
CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 CHEMBL489251 Ki 7.9 nM
O=C(NC1CCCCC1)c1cc2cccnc2n(CCN2CCOCC2)c1=O CHEMBL466623 Ki 7.9 nM
CC(C)(C)c1nc2c(n1CC1CC1)CCN(S(=O)(=O)c1ccccc1)C2 CHEMBL564244 EC50 7.9 nM
CCc1cnc(NC(=O)C(C)(C)CC)cc1CN1CCOCC1 CHEMBL570792 Ki 7.9 nM
CN(C)CCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc21 CHEMBL2152805 Ki 7.9 nM
O=C(NC1CCCCCC1)c1cc(/C=C/c2ccccc2)cn(Cc2ccc(F)cc2)c1=O CHEMBL3114343 Ki 7.9 nM
CN1CC(S(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2(O)CCOCC2)C1 CHEMBL3357383 EC50 7.9 nM
CC(C)CC(C#N)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3963482 EC50 7.9 nM
COc1ccc(-c2cn(Cc3ccc(F)cc3)c(=O)c(C(=O)NC3CCCCCC3)c2C)cc1 CHEMBL4175177 Ki 7.9 nM
Cc1nc(C(=O)NC2C3CC4CC(C3)C2C4)c(C)n1-c1ccccc1 CHEMBL598252 pEC50 7.943 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1nc(Cl)n(-c2ccccc2)c1Cl CHEMBL597083 pA2 7.943 nM
CCCCCn1cc(C(=O)c2ccccc2-c2ccccc2)c2ccccc21 CHEMBL1828801 pKi 7.943 nM
CCCCCn1cc(C(=O)Nc2cccc3ccccc23)c2ccccc21 CHEMBL1828805 pEC50 7.943 nM
CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCOCC4)n3)cc2)C1=O CHEMBL1835216 pEC50 7.943 nM
CCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 CHEMBL252536 pEC50 7.943 nM
COc1cccc2c(C(=O)N[C@@H](Cc3ccccc3)C(C)=O)c(C)n(CCN3CCOCC3)c12 CHEMBL78663 Ki 8.0 nM
COC(=O)[C@H](Cc1ccccc1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12 CHEMBL311690 Ki 8.0 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(C(F)(F)F)cc2S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL196518 Ki 8.0 nM
CCn1c2ccccc2c2cc(NC(=O)C3(S(=O)(=O)c4ccccc4)CC3)ccc21 CHEMBL460565 EC50 8.0 nM
CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(C(F)(F)F)cc1 CHEMBL512591 EC50 8.0 nM
O=C(Nc1cccc2ccccc12)n1c(=O)n(CCN2CCOCC2)c2ccccc21 CHEMBL494787 Ki 8.0 nM
C[C@H]1CC(CNS(=O)(=O)C(F)(F)F)CCN1S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F CHEMBL593434 Ki 8.0 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-n3ccnc3)ccc21 CHEMBL1215963 Ki 8.0 nM
CCCCCC1=NN(C(=O)NCC23CC4CC(CC(C4)C2)C3)CC1c1ccccc1 CHEMBL1224687 Ki 8.0 nM
FC(F)(F)c1cccc(-c2c[nH]c(-c3cccc(CN4CCOCC4)c3)n2)c1 CHEMBL1644675 EC50 8.0 nM
FC1CCN(Cc2cccc(-c3nc(-c4cccc(Cl)c4)c[nH]3)c2)CC1 CHEMBL1644689 EC50 8.0 nM
Clc1cccc(-c2c[nH]c(-c3cccc(CN4CCCCC4)c3)n2)c1Cl CHEMBL1644740 EC50 8.0 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(OC(=O)CCCN3CCOCC3)cc(C(C)(C)CCCCC#N)cc1OC2(C)C CHEMBL1668516 Ki 8.0 nM
CCCCCCn1cc(C(=O)NC2CCCCC2)c(=O)c2ccc(C)nc21 CHEMBL1668521 Ki 8.0 nM
Cn1nc(C(C)(C)C)cc1NC(=O)N1CCCN(c2ncc(C(F)(F)F)cc2Cl)CC1 CHEMBL1800692 EC50 8.0 nM
COCCn1c2c(cc(C(=O)NCc3ccccc3)c1=O)CCCCCC2 CHEMBL2387179 Ki 8.0 nM
O=C(NC1CCCCCC1)c1cccn(Cc2ccccc2)c1=O CHEMBL3114349 Ki 8.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(F)c(C(C)(C)O)c2)n1 CHEMBL3669073 IC50 8.0 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1)C(=O)O CHEMBL3931943 EC50 8.0 nM
CN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C1(C(F)(F)F)CC1 CHEMBL3906383 EC50 8.0 nM
CC(C)(C)OC(=O)N1CCC2(CCCN2C(=O)c2ccc(C3CC3)c(Cc3ccc(F)cc3)n2)CC1 CHEMBL3945765 EC50 8.0 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC(F)(C2CC2)C1 CHEMBL3936626 EC50 8.0 nM
CCCCCc1sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c(C(=O)OC)c1-c1ccccc1 CHEMBL4537616 Ki 8.03 nM
Cc1ccc(C(=O)N[C@H]2CC3CC[C@@]2(C)C3(C)C)cc1S(=O)(=O)N1CCOCC1 CHEMBL255096 Ki 8.1 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(CCO)c2n1 CHEMBL2057801 EC50 8.1 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(CCO)c2n1 CHEMBL3092907 EC50 8.1 nM
CCC1COc2c(N3CCCC3)ccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163571 Ki 8.12 nM
CC1(C)C(C(=O)c2cn(Cc3ccccc3)c3ccccc23)C1(C)C CHEMBL571774 pKi 8.128 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1C(F)(F)F CHEMBL384897 Ki 8.2 nM
CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)CC4CC4)ccc32)CC1 CHEMBL1950926 EC50 8.2 nM
CCCCn1cc(C(=O)NC(C)(C)C)c(=O)c2cccc(OC)c21 CHEMBL3409150 Ki 8.2 nM
CCN1CCC[C@H]1COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCCO1 CHEMBL3686308 Ki 8.2 nM
CNC(=O)[C@H](CC(C)(C)C)NC(=O)c1cccc(Cc2ccc(F)cc2)n1 CHEMBL3934815 EC50 8.2 nM
CCCCCn1cc(C(=O)Cc2ccccc2C)c2ccccc21 CHEMBL364820 EC50 8.3 nM
CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2C[C@H]2CCCO2)cc1 CHEMBL512886 EC50 8.3 nM
CC1(C)C(C(=O)c2cn(CCc3nsc(Cl)n3)c3ccccc23)C1(C)C CHEMBL568796 Ki 8.3 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(C3=CCCCC3)ccc21 CHEMBL1215919 Ki 8.3 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(O)ccc23)C1(C)C CHEMBL409491 Ki 8.3 nM
CCCCCn1cc(C(=O)Nc2ccccc2)c(=O)cc1C(C)(C)C CHEMBL2170547 EC50 8.3 nM
CNC(=O)[C@H](CC(C)(C)C)NC(=O)c1ccc(N2CCC23COC3)c(OCC2CC2)n1 CHEMBL3984450 EC50 8.3 nM
CC(CC1CC1)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)c1noc(N)n1 CHEMBL3901550 EC50 8.3 nM
CCCCCOc1c(OC)ccc2c(=O)n(CCc3ccncc3)ccc12 CHEMBL3410823 pKi 8.395 nM
CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCS(=O)(=O)CC2)c1 CHEMBL605199 Ki 8.4 nM
Cc1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(Br)n1-c1ccccc1 CHEMBL606377 Ki 8.4 nM
C[C@@H](NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)n2cccc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL1270479 Ki 8.4 nM
CC(C)(C)c1cc(NC(=O)N2CCCN(C(=O)[C@H]3CC[C@@H](O)CC3)CC2)no1 CHEMBL1762421 EC50 8.4 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCN(C(C)=O)CC1 CHEMBL1950923 EC50 8.4 nM
CC(C)(C)c1nc2cc(S(=O)(=O)CC3CC3)ccc2n1CC1CCS(=O)(=O)CC1 CHEMBL1950927 EC50 8.4 nM
CC(C)(C)c1nc2cc(S(=O)(=O)c3nccs3)ccc2n1CC1CCN(C=O)CC1 CHEMBL1950933 EC50 8.4 nM
COC(=O)N[C@]12CC3CC(C1)C[C@](c1cc(O)c4c(c1)OC(C)(C)[C@@H]1CC[C@@H](O)C[C@@H]41)(C3)C2 CHEMBL3416121 Ki 8.4 nM
CC(C)(O)COc1ccc(C(F)(F)F)cc1C(=O)/N=c1\sc2ccncc2n1CCCC(F)(F)F CHEMBL3647326 Ki 8.4 nM
CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)n2nc(-c3ccccc3)nc12 CHEMBL3774565 Ki 8.4 nM
CC(C)C[C@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 CHEMBL3894382 EC50 8.4 nM
Cc1nc(C(C)(CC2CC2)NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1 CHEMBL3949921 EC50 8.4 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCN3CCCC3)cc1OC2(C)C CHEMBL4239541 Ki 8.4 nM
Cc1c(CN2CCOCC2)c2ccccc2n1C(=O)c1cccc2ccccc12 CHEMBL73206 Ki 8.5 nM
Cc1c(CCN2CCOCC2)c2ccccc2n1C(=O)c1cccc2ccccc12 CHEMBL307627 Ki 8.5 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccco3)cc(OC)c21 CHEMBL1814462 Ki 8.5 nM
CC1(C)CC(n2ncc3c(cnn3CCN3CCOCC3)c2=O)CC(C)(C)C1 CHEMBL3696850 IC50 8.5 nM
CCCCn1nc(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1ONC(C)(C)C CHEMBL3650101 Ki 8.5 nM
CN(C(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(C)(C)C CHEMBL3900956 EC50 8.5 nM
C[C@H](/C=C\C/C=C\C/C=C\CCCC(=O)NC1CC1)/C=C\CCCCCN=[N+]=[N-] CHEMBL4213900 Ki 8.5 nM
Cc1cc(NC(=O)C2CCCCC2C)cc(CN2CCOCC2)c1C CHEMBL568468 Ki 8.6 nM
CC(C)C(NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(=O)N(C)C CHEMBL3946399 EC50 8.6 nM
CCCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 CHEMBL1641946 EC50 8.7 nM
Cc1nc(C(C)(C)NC(=O)c2cccc(-c3ccc(F)c(Cl)c3)n2)no1 CHEMBL3935837 EC50 8.7 nM
O=C(c1cccc2ccccc12)c1cn(CCN2CCOCC2)c2ccc(O)cc12 CHEMBL78627 EC50 8.7 nM
CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)c2c(C)noc21 CHEMBL2316279 Ki 8.74 nM
Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cc(C(F)(F)F)ccc2F)n1CC1CC1 CHEMBL402938 EC50 8.8 nM
C#Cc1ccc2c(c1)c(=O)c(C(=O)NC13CC4CC(CC(C4)C1)C3)cn2CCCCC CHEMBL1215888 Ki 8.8 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n([C@@H]3CCOC3)c2n1 CHEMBL2057803 EC50 8.8 nM
Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n([C@@H]3CCOC3)c2n1 CHEMBL3092899 EC50 8.8 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(C=C3C4CC5CC(C4)CC3C5)cc1OC2(C)C CHEMBL191324 Ki 8.9 nM
CC(C)(C)Cc1nc2cc(S(=O)(=O)C3CNC3)ccc2n1CC1CC1 CHEMBL3357364 EC50 8.9 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)NC CHEMBL3905855 EC50 8.9 nM
CNC(=O)[C@@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C CHEMBL4107944 EC50 8.9 nM
Cc1nc(C(C)(NC(=O)c2cc(OCC(F)(F)F)c(Cl)cn2)C2CC2)no1 CHEMBL3899824 EC50 8.9 nM
C[C@H](Oc1cc(C(=O)NC(C(N)=O)C2(C)COC2)ncc1C1CC1)C(F)(F)F CHEMBL3932300 EC50 8.9 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cn2c3c(cccc3c1=O)OCC2C1CC1 CHEMBL2163943 Ki 8.92 nM
CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(-c3ccccc3C)cc12 CHEMBL2380327 Ki 8.93 nM
C[C@H](NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccccc2S(=O)(=O)c2ccccc2F)cc1 CHEMBL199139 Ki 9.0 nM
CCC1(CC)CS/C(=N\c2ccccc2C(C)C)N(C(=S)SC)C1 CHEMBL391561 Ki 9.0 nM
O=C(N[C@@H]1CCCc2ccccc21)N1Cc2ccccc2N(CCN2CCOCC2)C1=O CHEMBL521668 Ki 9.0 nM
C[C@H]1CC[C@H](NC(=O)c2cc3cccnc3n(Cc3ccc(F)cc3)c2=O)CC1 CHEMBL512063 Ki 9.0 nM
CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCCCCC2)c1 CHEMBL602591 Ki 9.0 nM
O=S(=O)(c1cc2ccccc2n1S(=O)(=O)c1ccccc1F)N1C[C@@H]2[C@@H](CNS(=O)(=O)C(F)(F)F)[C@@H]2C1 CHEMBL1270481 Ki 9.0 nM
CC(=O)n1cc(-c2cccc(C(F)(F)F)c2)nc1-c1cccc(CN2CCOCC2)c1 CHEMBL1644672 EC50 9.0 nM
FC1CCN(Cc2cccc(-c3nc(-c4cccc(C(F)(F)F)c4)c[nH]3)c2)CC1 CHEMBL1644682 EC50 9.0 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(N)cc23)C1(C)C CHEMBL259462 Ki 9.0 nM
CCC(C)(C)C(=O)Cc1cc(C)c(C)c(S(=O)(=O)N2CCCCCC2)c1 CHEMBL1668513 Ki 9.0 nM
CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCOCC1)CC2 CHEMBL1950351 Ki 9.0 nM
O=C(NC1(C(=O)O)CCCCC1)c1cc2c(n(Cc3ccc(F)cc3)c1=O)CCCCCC2 CHEMBL2019086 IC50 9.0 nM
O=C(NC1CCCCC1)c1cc2ccccc2n(CCN2CCOCC2)c1=O CHEMBL2022362 Ki 9.0 nM
CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C CHEMBL2170550 Ki 9.0 nM
CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2[C@@H]2C[C@@H](C=O)CC[C@H]21 CHEMBL2348460 Ki 9.0 nM
CCCCCCC(C)(C)c1cc(O)c([C@H]2CC(=O)[C@H]3C[C@@H]2C3(C)C)c(OC(=O)/C=C/C(=O)O)c1 CHEMBL3234035 Ki 9.0 nM
C[C@H](NS(=O)(=O)/C=C/c1n[nH]c2c1CCCC[C@@H]2Cc1cccc(F)c1)c1ccccc1 CHEMBL3233029 EC50 9.0 nM
CC(C)Cn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1OCC1CCO1 CHEMBL3647303 Ki 9.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc3c(c2)OCO3)n1 CHEMBL3669068 IC50 9.0 nM
COc1nc(NCCc2ccc(OC(F)(F)F)cc2)nc(-c2ccc(OC)c(C(C)(C)O)c2)n1 CHEMBL3669110 IC50 9.0 nM
COc1nc(NCCc2ccc(F)cc2)nc(-c2cccc(C(C)(C)O)c2)n1 CHEMBL3669057 IC50 9.0 nM
COc1nc(NCCc2ccc(OCF)cc2)nc(-c2ccc(OC)c(C(C)(C)O)c2)n1 CHEMBL3669119 IC50 9.0 nM
CC1(C)CCN(C(=O)c2ccc(C3CC3)c(Cc3ccc(F)cc3)n2)CC1 CHEMBL3950636 EC50 9.0 nM
Cc1cc(-c2cc(C(=O)N[C@H]3CC[C@H](C)CC3)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl CHEMBL4085733 Ki 9.0 nM
CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@H]1CC=C(C)C[C@H]21 CHEMBL58501 Ki 9.0 nM
CCCCCN1C(=O)/C(=C/NC2CCCCC2)C(=O)c2ccc(C)cc21 CHEMBL3590290 IC50 9.03 nM
CCCCCC[Si](C)(C)c1cc(O)c(C2CCCCC2)c(O)c1 CHEMBL5176902 Ki 9.08 nM
CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1cccc(F)c1 CHEMBL220304 Ki 9.1 nM
CC(C)(C)Cc1nc2c(n1CC1CC1)CCN(S(=O)(=O)c1ccccc1)C2 CHEMBL563352 EC50 9.1 nM
CCCCCN1N=C(C(=O)N[C@H]2C[C@H]3CC[C@]2(C)C3(C)C)CC1c1ccccc1F CHEMBL1223835 Ki 9.1 nM
O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1C[C@@H]2C[C@H]1CS2 CHEMBL3932847 EC50 9.1 nM
CCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc21 CHEMBL579241 pKi 9.12 nM
CCCCO/N=C(\C)c1cc(O)c2c(c1)OC(C)(C)[C@H]1CC=C(C)C[C@H]21 CHEMBL4240996 EC50 9.14 nM
C=CCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2c(OC)ccc(OC)c21 CHEMBL498132 Ki 9.2 nM
CCCCn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(C(F)(F)F)ccc1OC[C@@H]1CCCN1C CHEMBL3647308 Ki 9.2 nM
CC(C)[C@](C)(CO)NC(=O)c1cc(OCC2CCC2)c(Cl)cn1 CHEMBL3952061 EC50 9.2 nM
CC(C)C[C@@H]1COc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn1c23 CHEMBL2163928 Ki 9.24 nM
CCC1COc2cccc3c(=O)c(C(=O)NC4CCCCCC4)cn1c23 CHEMBL2163964 Ki 9.24 nM
COC(=O)c1c(NC(=O)C23CC4CC(CC(C4)C2)C3)sc(C)c1C CHEMBL4440363 Ki 9.24 nM
CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cccc(OCc4ccccc4)c23)C1(C)C CHEMBL410842 Ki 9.3 nM
CN(C)C(=O)[C@H](CC1CC1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3911409 EC50 9.3 nM
CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(-c3cccc4ccccc34)cc1OC2(C)C CHEMBL381492 Log Ki 9.333 nM
C=CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(Br)ccc21 CHEMBL500415 Ki 9.4 nM
Cc1ccc(NC(=O)[C@H]2C(C)(C)[C@@H]3CC[C@@]2(C)C3)cc1S(=O)(=O)N1CCOCC1 CHEMBL516057 Ki 9.4 nM
CC(C)(C)c1c/c(=N\C(=O)c2cccc(C(F)(F)F)c2)n(CC2CC2)s1 CHEMBL257224 IC50 9.5 nM
O=C(Nc1sc2c(c1C(=O)N1CCCCC1)CCOC2)c1ccccc1OC(F)(F)F CHEMBL2205616 EC50 9.5 nM
CCN(CC)c1ccc(CN(Cc2ccco2)S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL2336536 Ki 9.5 nM
Cc1ccc(Cn2nc(C(=O)NCC3CCC4CC3C4(C)C)c3c2-c2ccc(Cl)cc2CCC3)cc1 CHEMBL3984538 Ki 9.5 nM
CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(=O)NC CHEMBL3959029 EC50 9.5 nM
NC(=O)C1CS(=O)(=O)CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3922428 EC50 9.5 nM
COC(=O)C(C)C(C)(C)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 CHEMBL3920679 EC50 9.5 nM
CCN(C(=O)c1cc(OCC2CC2)c(C2CC2)cn1)C(C)(C)C CHEMBL3923684 EC50 9.5 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1C=C[C@@](C)(O)C[C@@H]21 CHEMBL4282822 Ki 9.5 nM
CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2c(C)nn(C)c21 CHEMBL2316299 Ki 9.51 nM
CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccco3)cc12 CHEMBL2381672 Ki 9.52 nM
CCCc1ccc(C(=O)c2cn(CCC)c3ccccc23)c2ccccc12 CHEMBL539479 pKi 9.594 nM
CCCCOc1c(O[11CH3])ccc2cc(C(=O)NC3CCCCC3)c(=O)[nH]c12 CHEMBL1081610 Ki 9.6 nM
CCS(=O)(=O)c1ccc2c(c1)nc(C1(C)CCCC1)n2CC1CC1 CHEMBL1800175 EC50 9.6 nM
CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C(C)(C)C CHEMBL2170549 Ki 9.6 nM
CC(=O)N1CC(S(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)C1 CHEMBL3357366 EC50 9.6 nM
CC1(C)Oc2cc([C@]34CC5CC(C[C@@](CN=[N+]=[N-])(C5)C3)C4)cc(O)c2[C@@H]2C[C@H](O)CC[C@H]21 CHEMBL3416129 Ki 9.6 nM
CC(C)(OC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1)c1cc(N)on1 CHEMBL3582025 EC50 9.6 nM
COC(=O)[C@H](CC1CC1)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 CHEMBL3903525 EC50 9.6 nM
CCCCOc1c(OC)ccc2cc(C(=O)NC3CCCCC3)c(=O)[nH]c12 CHEMBL2068805 Ki 9.6 nM
CCCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCOCC2)c1 CHEMBL595035 Ki 9.7 nM
Cc1nc(C(=O)NC23CC4CC(CC2C4)C3)c(C)n1-c1ccccc1 CHEMBL1668515 Ki 9.7 nM
CC1=CC[C@H]2[C@H](C1)c1c(O)cc(/C(C)=N/OCCCCF)cc1OC2(C)C CHEMBL4242964 Ki 9.7 nM
O=C(N/N=C1\C(=O)N(CC2CCCCC2)c2ccccc21)c1ccccc1 CHEMBL514565 EC50 9.8 nM
CC(C)(C)c1ccc(NC(=O)N2CCCN(C(=O)c3ccc(Cl)cc3)CC2)cc1 CHEMBL1762287 EC50 9.8 nM
CCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc21 CHEMBL2380416 Ki 9.8 nM
CNC(=O)[C@@H](NC(=O)c1cc(OCC(F)(F)F)c(Cl)cn1)C(C)(C)C CHEMBL4114825 EC50 9.8 nM
CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)c2c(C)nn(C)c21 CHEMBL2316300 Ki 9.83 nM
CCn1c(C(=O)NCc2ccccc2Cl)nc2c(-c3ccccc3)cccc21 CHEMBL3114519 EC50 9.9 nM
CC(C)Cn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1OC1CC1 CHEMBL3647314 Ki 9.9 nM