COc1ccc(Cl)cc1S(=O)(=O)c1cn(CCC(=O)O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431816 IC50 7.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431624 IC50 11.6 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CC(N)=O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431814 IC50 12.8 nM
O=C1Cc2cc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)ccc2N1 CHEMBL3431540 IC50 13.2 nM
COc1ccc(Cl)cc1S(=O)(=O)c1nn(CCC(=O)O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431837 IC50 14.7 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CCCC(=O)O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431830 IC50 15.15 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C(=O)O)Oc2ccc(C(=O)Nc3cccc(F)c3)cc21 CHEMBL2216778 IC50 16.0 nM
O=C(O)c1ccc(NC(=O)c2ccc3ccn(S(=O)(=O)c4cccc(Cl)c4)c3c2)cc1 CHEMBL3431629 IC50 16.7 nM
Cc1cc(C)cc(S(=O)(=O)N2CCc3ccc(C(=O)Nc4nc(CC(=O)O)cs4)cc32)c1 CHEMBL3431752 IC50 16.7 nM
COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3431919 IC50 17.5 nM
COc1ccc(Cl)cc1S(=O)(=O)Nc1cccc(C(=O)Nc2ccc(-c3nnn[nH]3)cc2)c1 CHEMBL3431533 IC50 18.6 nM
Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL3431642 IC50 18.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431820 IC50 19.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccccn2)cs1 CHEMBL2216774 IC50 19.6 nM
O=C([O-])c1cccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431807 IC50 19.65 nM
O=C(Nc1ccc(-c2nnn[nH]2)cc1)c1cccc(NS(=O)(=O)c2cccc(Cl)c2)c1 CHEMBL3431514 IC50 20.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL2216779 IC50 20.6 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C(=O)O)Cc2ccc(C(=O)Nc3ccccc3)cc21 CHEMBL3431845 IC50 20.8 nM
COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 CHEMBL3431634 IC50 21.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431627 IC50 22.3 nM
O=C(O)Cc1csc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CCO3)n1 CHEMBL3431678 IC50 22.6 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(F)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431512 IC50 23.9 nM
CN1CCN(C(=O)COc2ccccc2)[C@@H](c2nc(-c3ccc4[nH]nnc4c3)no2)C1 CHEMBL3431560 IC50 24.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccnc2)cs1 CHEMBL3431808 IC50 25.0 nM
O=C(NCc1cccs1)c1nn(Cc2cccc(C(F)(F)F)c2)c2ccccc12 CHEMBL2216776 IC50 26.0 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc3[nH]cnc3c2)no1 CHEMBL3431542 IC50 26.05 nM
CC(=O)Nc1cc(F)cc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431672 IC50 26.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431535 IC50 26.7 nM
Cc1cc(C)cc(S(=O)(=O)c2nn(CCC(=O)O)c3ccc(C(=O)Nc4ccccc4)cc23)c1 CHEMBL3431842 IC50 27.0 nM
CC(=O)Nc1cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)ccc1F CHEMBL3431675 IC50 27.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3[nH]cnc3c2)n1 CHEMBL3431503 IC50 29.2 nM
COc1ccc(C)cc1S(=O)(=O)n1ccc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431628 IC50 29.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCS(=O)(=O)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431504 IC50 30.0 nM
Cc1cc(C)cc(S(=O)(=O)N2CCS(=O)(=O)c3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL3431789 IC50 31.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431622 IC50 31.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(C2C[C@@H]3CC[C@H]2C3)n1 CHEMBL3431475 IC50 32.6 nM
CC(=O)Nc1ccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431851 IC50 32.6 nM
O=C(O)c1cccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431806 IC50 33.5 nM
Cc1cc(C)cc(S(=O)(=O)c2nn(CC(=O)O)c3ccc(C(=O)Nc4ccccc4)cc23)c1 CHEMBL3431841 IC50 33.7 nM
NC(=O)c1ccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431515 IC50 34.2 nM
O=C(O)c1ccc(NC(=O)c2cccc(S(=O)(=O)N3CCCc4ccc(C(F)(F)F)cc43)c2)cc1 CHEMBL3431518 IC50 34.2 nM
Nc1ccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cn1 CHEMBL3431502 IC50 34.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C(=O)O)Oc2ccc(C(=O)Nc3ccccc3)cc21 CHEMBL3431704 IC50 34.5 nM
Cc1cc(C)cc(S(=O)(=O)n2ccc3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL3431630 IC50 35.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc3[nH]c(=O)[nH]c3c2)no1 CHEMBL3431537 IC50 35.4 nM
CCC(=O)Nc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431578 IC50 35.6 nM
O=C1COc2ccc(-c3nc([C@H]4CCCCN4C(=O)COc4ccccc4)no3)cc2N1 CHEMBL3431631 IC50 35.8 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CC(=O)O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431815 IC50 36.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(O)c2)no1 CHEMBL3431591 IC50 36.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1C[C@@H](C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431499 IC50 36.7 nM
CN1CCN(C(=O)COc2ccccc2)[C@@H](c2nc(-c3cccc(C(F)(F)F)c3)n[nH]2)C1 CHEMBL3431539 IC50 37.0 nM
O=C(O)c1cccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)n1 CHEMBL3431858 IC50 37.7 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431552 IC50 38.1 nM
COc1ccc(Cl)cc1S(=O)(=O)c1nn(CC(=O)O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431836 IC50 38.4 nM
COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc12 CHEMBL3431461 IC50 39.3 nM
COc1ccc(Cl)cc1Cc1c[nH]c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc12 CHEMBL3431727 IC50 39.3 nM
COc1ccc(Cl)cc1Cc1cn(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3431720 IC50 39.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431536 IC50 40.05 nM
CCN(CC)C(=O)c1ccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431519 IC50 40.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1C[C@@H](C(=O)O)Oc2ccc(C(=O)Nc3ccccc3)cc21 CHEMBL3431833 IC50 40.2 nM
N#Cc1ccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431854 IC50 40.5 nM
COc1ccc(Cl)cc1Cc1cn(C)c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc12 CHEMBL3431711 IC50 40.6 nM
O=C(O)Cc1csc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CC3)n1 CHEMBL3431753 IC50 40.7 nM
NC(=O)c1cccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431524 IC50 40.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccccc3)cc21 CHEMBL3431505 IC50 40.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ncc(CC(=O)O)s3)cc21 CHEMBL3431754 IC50 41.6 nM
COc1ccc(Cl)cc1S(=O)(=O)c1nn(C)c2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc12 CHEMBL3431839 IC50 41.6 nM
Cc1cc(C)cc(S(=O)(=O)N2CCOc3ccc(C(=O)Nc4nc(CC(=O)O)cs4)cc32)c1 CHEMBL3431679 IC50 42.4 nM
COC(=O)c1cccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)n1 CHEMBL3431849 IC50 42.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431895 IC50 42.5 nM
Cn1cc(Sc2cccc(Cl)c2)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL3431641 IC50 43.4 nM
COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc(OC)c1OC CHEMBL3431522 IC50 43.6 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(Cl)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431917 IC50 43.6 nM
CC(=O)Nc1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431581 IC50 43.8 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CCO)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431831 IC50 43.85 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CCCO)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431832 IC50 45.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431915 IC50 46.3 nM
COc1ccc(Cl)cc1S(=O)(=O)N1C[C@H](C(=O)O)Oc2ccc(C(=O)Nc3ccccc3)cc21 CHEMBL3431834 IC50 46.6 nM
COc1ccc(Cl)cc1CN1C(=O)C(C)(C)c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431632 IC50 46.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431821 IC50 47.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cnnc3ccccc23)n1 CHEMBL3431494 IC50 49.1 nM
COc1ccc(Cl)cc1S(=O)(=O)c1nn(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3431782 IC50 50.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(Cl)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431882 IC50 50.3 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431638 IC50 50.5 nM
O=C1CN(c2cccc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)c2)C(=O)N1 CHEMBL3431760 IC50 50.6 nM
CC(=O)Nc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)ccn1 CHEMBL3431645 IC50 50.9 nM
Cc1cc(C)cc(S(=O)(=O)N2CCSc3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL3431793 IC50 51.0 nM
Cc1cc(C)cc(S(=O)(=O)c2n[nH]c3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc23)c1 CHEMBL3431843 IC50 51.2 nM
CC(=O)c1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)cc1 CHEMBL3431484 IC50 51.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2nc(CC(=O)O)cs2)cc2c1OCO2 CHEMBL3431825 IC50 51.5 nM
CCNC(=O)Nc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431582 IC50 52.3 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431470 IC50 53.3 nM
CC(=O)Nc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431529 IC50 53.7 nM
COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(C(=O)Nc2ccccc2)ccc1CCC(=O)O CHEMBL3431798 IC50 53.7 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431719 IC50 53.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431649 IC50 54.0 nM
O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CCS3(=O)=O)cc1 CHEMBL3431788 IC50 54.2 nM
COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431822 IC50 54.6 nM
O=C1COc2ccc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 CHEMBL3431655 IC50 55.7 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431585 IC50 56.1 nM
Cc1cccc(S(=O)(=O)N2CCOc3ccc(C(=O)Nc4nc(CC(=O)O)cs4)cc32)c1 CHEMBL3431677 IC50 56.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2cccnc2)n1 CHEMBL3431869 IC50 56.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(F)cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431912 IC50 57.45 nM
COc1ccc(Cl)cc1CN1C(=O)OC(C)(C)c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431507 IC50 58.7 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cccc(-n3cn[nH]c3=O)c2)n1 CHEMBL3431713 IC50 59.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COCc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431647 IC50 59.65 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(N3CCCS3(=O)=O)c2)no1 CHEMBL3431758 IC50 59.7 nM
Cc1cc(C)cc(S(=O)(=O)N2CC[S+]([O-])c3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL3431796 IC50 59.8 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cccc(-n3cc[nH]c3=O)c2)n1 CHEMBL3431741 IC50 59.9 nM
COc1ccc(Cl)cc1S(=O)(=O)c1c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc2nn1C CHEMBL3431783 IC50 60.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(S(=O)(=O)NCCO)cc2)no1 CHEMBL3431525 IC50 60.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(-c4noc(=O)[nH]4)cc3)cc21 CHEMBL3431544 IC50 61.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cccc(C(=O)Nc2nc(CC(=O)O)cs2)c1 CHEMBL3431773 IC50 61.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431896 IC50 61.7 nM
COc1ccc(Cl)cc1Sc1cn(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3431908 IC50 61.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431900 IC50 62.2 nM
NC(=O)c1n[nH]c2cc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)ccc12 CHEMBL3431561 IC50 63.5 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(C3CCOC3)cc2C1 CHEMBL3431739 IC50 63.5 nM
NC(=O)COc1cccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431902 IC50 63.6 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(O[C@@H]3CCOC3)cc2C1 CHEMBL3431802 IC50 63.6 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(C3CCOCC3)cc2C1 CHEMBL3431737 IC50 63.8 nM
COc1ccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL2216775 IC50 65.0 nM
N#Cc1cccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431855 IC50 65.0 nM
O=C1CN(c2cccc(-c3nc([C@H]4CCCCN4C(=O)COc4ccccc4)no3)c2)C(=O)N1 CHEMBL3431714 IC50 65.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431573 IC50 65.15 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431472 IC50 65.4 nM
CS(=O)(=O)NCc1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431510 IC50 65.4 nM
O=C1Cc2cc(-c3csc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)ccc2N1 CHEMBL3431850 IC50 65.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431606 IC50 66.1 nM
O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CCO3)cc1 CHEMBL3431611 IC50 66.4 nM
O=C(O)Cc1ccc(NC(=O)c2ccc3ccn(S(=O)(=O)c4cccc(Cl)c4)c3c2)cc1 CHEMBL3431687 IC50 66.8 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cccc(N3CCCS3(=O)=O)c2)n1 CHEMBL3431715 IC50 67.0 nM
COc1ccc(Cl)cc1CN1C(=O)C(C)(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431633 IC50 67.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(B(O)O)c2)no1 CHEMBL3431608 IC50 67.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2 CHEMBL3431880 IC50 67.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccncc2)cs1 CHEMBL3431810 IC50 68.0 nM
CCOC(=O)c1cn2ccc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2n1 CHEMBL3431567 IC50 68.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc([N+](=O)[O-])o2)no1 CHEMBL3431698 IC50 68.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(Cl)cc(C(=O)Nc3ncc(CC(=O)O)s3)cc21 CHEMBL3431926 IC50 68.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431602 IC50 71.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCNc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431576 IC50 71.3 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3431909 IC50 71.6 nM
CC(C)C(=O)Nc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431579 IC50 72.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431548 IC50 72.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(O)cc2)no1 CHEMBL3431593 IC50 73.2 nM
CCn1c(C)nc(Cl)c1-c1noc([C@H]2CCCCN2C(=O)COc2ccccc2)n1 CHEMBL3431465 IC50 73.75 nM
CCn1cc(S(=O)(=O)c2cc(Cl)ccc2OC)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL3431478 IC50 74.7 nM
Cc1cc(C)cc(S(=O)(=O)c2nn(C)c3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc23)c1 CHEMBL3431844 IC50 74.9 nM
Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cc(C(=O)Nc3nc(CC(=O)O)cs3)ccc21 CHEMBL3431685 IC50 75.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1C[C@H](C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431498 IC50 75.7 nM
O=C1CCC(=O)N1c1cc(F)cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431772 IC50 75.7 nM
NC(=O)c1ccc(C#C[C@H]2CCCCN2C(=O)COc2ccccc2)cc1 CHEMBL3431710 IC50 75.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(Cl)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431914 IC50 77.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c1cc(C(=O)Nc1ccc(C(=O)O)cc1)cc2C(F)(F)F CHEMBL3431918 IC50 77.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431605 IC50 77.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(F)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431903 IC50 77.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(C)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431916 IC50 78.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3snnc3c2)n1 CHEMBL3431491 IC50 78.4 nM
CCOC(=O)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431563 IC50 78.6 nM
Cc1nn(C)c(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1Cl CHEMBL3431468 IC50 79.1 nM
Cn1cnc(Br)c1-c1noc([C@H]2CCCCN2C(=O)COc2ccccc2)n1 CHEMBL3431466 IC50 79.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3[nH]nnc3c2)n1 CHEMBL3431495 IC50 79.4 nM
COc1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)cn1 CHEMBL3431872 IC50 79.4 nM
CC(=O)Nc1cc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)ccc1F CHEMBL3431673 IC50 79.5 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(O)cc2)cs1 CHEMBL3431852 IC50 79.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(-c3nnco3)c2)n[nH]1 CHEMBL3431601 IC50 80.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(C)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431721 IC50 80.1 nM
O=C(O)c1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)c1 CHEMBL3431847 IC50 80.3 nM
O=C(c1cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)ccn1)N1CCOCC1 CHEMBL3431526 IC50 80.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2nc(CC(=O)O)cs2)cc2c1OCCO2 CHEMBL3431827 IC50 80.5 nM
N#Cc1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)cc1 CHEMBL3431904 IC50 80.7 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C(=O)O)Oc2ccc(C(=O)Nc3ccc(F)cc3)cc21 CHEMBL3431785 IC50 80.9 nM
O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CCS3)cc1 CHEMBL3431794 IC50 82.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(F)c2)n[nH]1 CHEMBL3431701 IC50 82.7 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cc[nH]c(=O)c2)no1 CHEMBL3431592 IC50 83.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431764 IC50 84.0 nM
COc1ccc(Cl)cc1S(=O)(=O)c1nn(C)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431786 IC50 84.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3ccn(CC(=O)O)n3)cc21 CHEMBL3431835 IC50 84.7 nM
N#Cc1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431905 IC50 84.8 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(C2(C(F)(F)F)CC2)n1 CHEMBL3431650 IC50 85.8 nM
O=C(O)c1ccc(NC(=O)c2ccc(Cl)c(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)c2)cc1 CHEMBL3431521 IC50 86.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(C2CCCCC2)n1 CHEMBL3431473 IC50 86.5 nM
NS(=O)(=O)c1ccc(C#C[C@H]2CCCCN2C(=O)COc2ccccc2)cc1 CHEMBL3431706 IC50 86.6 nM
NS(=O)(=O)c1cccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431516 IC50 87.0 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cccc3[nH]cnc23)n1 CHEMBL3431483 IC50 87.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc3[nH]ncc3c2)n[nH]1 CHEMBL3431565 IC50 87.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431765 IC50 87.4 nM
CN1CCN(c2cc3c(cc2Cl)CN(C(=O)[C@H]2CCCCN2C(=O)COc2ccccc2)C3)CC1 CHEMBL3431734 IC50 87.8 nM
CCN(c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431886 IC50 88.4 nM
COc1ccc(Cl)cc1CN1C(=O)OC(C)(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431506 IC50 88.5 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(Br)s2)cs1 CHEMBL3431857 IC50 88.6 nM
O=C(COc1ccccc1)N1CCNCC1c1nc(-c2ccc(N3CCOCC3)cc2)no1 CHEMBL3431534 IC50 88.7 nM
Cc1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)cn1 CHEMBL3431868 IC50 88.7 nM
O=C1CCCN1c1cccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431759 IC50 88.8 nM
O=C(COc1ccccc1)N1CCOC[C@@H]1c1nc(-c2ccc3[nH]cnc3c2)no1 CHEMBL3431500 IC50 89.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cnc3[nH]cnc3c2)n1 CHEMBL3431643 IC50 90.2 nM
O=C(Nc1ccc(C(=O)O)c(Cl)c1)c1ccc2c(c1)N(S(=O)(=O)c1cc(Cl)cc(Cl)c1)CC2 CHEMBL3431550 IC50 90.25 nM
COc1ccc(Cl)cc1CN1C(=O)C2(CC2)c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431797 IC50 91.1 nM
CC1(C)NC(=O)N(c2ccc(Cl)c(-c3nc([C@H]4CCCCN4C(=O)COc4ccccc4)no3)c2)C1=O CHEMBL3431479 IC50 91.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc(-n3cncn3)cc2)n1 CHEMBL3431481 IC50 91.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C)c2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431898 IC50 92.2 nM
Cc1sc([C@H]2CCCCN2C(=O)COc2ccccc2)nc1-c1cccc(C(=O)O)c1 CHEMBL3431878 IC50 92.3 nM
NC(=O)c1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431531 IC50 93.1 nM
O=C(O)c1cccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431517 IC50 93.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC[S+]([O-])c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431659 IC50 94.1 nM
O=C1CNc2ccc(-c3nc([C@H]4CCCCN4C(=O)COc4ccccc4)no3)cc2N1 CHEMBL3431660 IC50 94.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(Cl)nc2)cs1 CHEMBL3431856 IC50 95.0 nM
O=C1Cc2ccc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 CHEMBL3431460 IC50 95.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(-n3cn[nH]c3=O)c2)no1 CHEMBL3431761 IC50 96.3 nM
CCN(c1cc(C(=O)Nc2nc(CC(=O)O)cs2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431884 IC50 96.3 nM
NC(=O)c1cn2ccc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2n1 CHEMBL3431568 IC50 96.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431635 IC50 96.8 nM
O=C1CN(c2cccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)c2)C(=O)N1 CHEMBL3431790 IC50 96.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431626 IC50 97.4 nM
O=C1Nc2ccc(-c3noc([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2CO1 CHEMBL3431751 IC50 98.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc(-n3cnnn3)cc2)n1 CHEMBL3431482 IC50 98.6 nM
CC(=O)NCc1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431509 IC50 99.3 nM
COc1ccc(Cl)cc1Cn1cc(C(=O)O)c2ccc(C(=O)Nc3ccccc3)cc21 CHEMBL3431770 IC50 99.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cccc3[nH][nH]c(=O)c23)n1 CHEMBL3431667 IC50 99.8 nM
O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1ccc(Cl)c(Cl)c1)CC2 CHEMBL3431547 IC50 102.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCS(=O)(=O)c2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431763 IC50 102.3 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(OC3CCOCC3)cc2C1 CHEMBL3431801 IC50 103.3 nM
CCOc1ccc(C(=O)Nc2ccc(CC(=O)O)cc2)cc1N(CCS(=O)O)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431724 IC50 104.7 nM
O=C1Cc2cc(-c3noc([C@H]4CNCCN4C(=O)COc4ccccc4)n3)ccc2N1 CHEMBL3431558 IC50 104.95 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccccc2F)n[nH]1 CHEMBL3431700 IC50 105.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccs2)n[nH]1 CHEMBL3431699 IC50 107.8 nM
CC(=O)Nc1ccc(-n2nnc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431709 IC50 107.9 nM
Nc1cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)ccn1 CHEMBL3431572 IC50 108.0 nM
CC(=O)Nc1cccc(C#C[C@H]2CCCCN2C(=O)COc2ccccc2)c1 CHEMBL3431644 IC50 108.2 nM
Nc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431528 IC50 109.4 nM
Nc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)ccn1 CHEMBL3431670 IC50 109.6 nM
NS(=O)(=O)c1ccc(-c2noc(C3C4CC4CN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431911 IC50 109.7 nM
CC(=O)Nc1cccc(-n2nnc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431508 IC50 110.8 nM
O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1cc(Cl)cc(Cl)c1)CCC2 CHEMBL3431553 IC50 110.9 nM
CN(C)C(=O)CCC(=O)Nc1cc(F)cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431769 IC50 110.9 nM
O=C(NC1CC1)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431619 IC50 111.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL3431575 IC50 111.2 nM
Nc1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)n1 CHEMBL3431665 IC50 111.2 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CS(C)(=O)=O)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431463 IC50 111.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCNc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431610 IC50 111.6 nM
NC(=O)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431566 IC50 112.95 nM
O=C1CCN1c1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431583 IC50 113.6 nM
COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431812 IC50 113.8 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc(-c3n[nH]c(=O)o3)c2)n[nH]1 CHEMBL3431600 IC50 115.4 nM
Cc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)on1 CHEMBL3431749 IC50 115.8 nM
Nc1ncc(Cl)c(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)n1 CHEMBL3431480 IC50 116.7 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(O[C@H]3CCOC3)cc2C1 CHEMBL3431803 IC50 118.1 nM
Cc1cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)n(C)n1 CHEMBL3431467 IC50 119.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431623 IC50 120.4 nM
O=C1COc2ccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 CHEMBL3431663 IC50 121.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cc(Cl)nnc2O)n1 CHEMBL3431651 IC50 121.6 nM
Cc1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)c1C CHEMBL3431520 IC50 122.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(Cl)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431883 IC50 122.3 nM
Nc1cc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)ccn1 CHEMBL3431594 IC50 122.6 nM
CS(=O)(=O)c1ccc(-n2nnc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431696 IC50 122.7 nM
CC(=O)Nc1cc(F)cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431674 IC50 122.8 nM
COc1ccc(Cl)cc1CN1C(=O)C2(CC2)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431811 IC50 123.2 nM
CCCN(c1cc(C(=O)Nc2nc(CC(=O)O)cs2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431888 IC50 123.6 nM
Cc1ccnc(N2CCN(C(=O)[C@H]3CCCCN3C(=O)COc3ccccc3)CC2)c1 CHEMBL3431778 IC50 124.2 nM
COc1ccc(Cl)cc1CN1C(=O)CSc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431646 IC50 124.8 nM
O=C(O)Cc1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CC3)cc1 CHEMBL3431691 IC50 125.1 nM
O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1cccc(C(F)(F)F)c1)CCC2 CHEMBL3431554 IC50 126.4 nM
O=C1CCC(=O)N1c1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431496 IC50 126.7 nM
COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(C(=O)Nc2ccc(C(=O)O)cc2)cn(C)c1=O CHEMBL3431555 IC50 126.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3cccnc3n2)n1 CHEMBL3431492 IC50 128.7 nM
O=C(O)c1ccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431805 IC50 129.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431897 IC50 129.6 nM
COc1ccc(Cl)cc1Cc1cn(C)c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 CHEMBL3431712 IC50 129.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1C#Cc1ccc2[nH]cnc2c1 CHEMBL3431723 IC50 129.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2n[nH]c3ccccc23)n1 CHEMBL3431863 IC50 130.0 nM
O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(Cl)c2)CC[S+]3[O-])cc1 CHEMBL3431795 IC50 130.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nnn(-c2ccc3[nH]ccc3c2)n1 CHEMBL3431708 IC50 130.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCCc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431612 IC50 131.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(F)cc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431913 IC50 131.4 nM
COc1ccc(Cl)cc1CN1C(=O)OCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431740 IC50 131.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431549 IC50 131.8 nM
O=C(COc1ccccc1)N1CCNC[C@@H]1c1nc(-c2ccc3[nH]cnc3c2)no1 CHEMBL3431556 IC50 131.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc2c1OCO2 CHEMBL3431829 IC50 133.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc3c(c2)OCO3)cs1 CHEMBL3431853 IC50 133.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N[C@@H]1CCCN(C(=O)COc2ccccc2)C1 CHEMBL3431586 IC50 133.95 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccn(CC(=O)O)n3)cc21 CHEMBL3431824 IC50 135.7 nM
COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(C(=O)Nc2ccccc2)ccc1/C=C/C(=O)O CHEMBL3431823 IC50 136.1 nM
O=C1Cc2cc(-c3noc(C4C5CC5CN4C(=O)COc4ccccc4)n3)ccc2N1 CHEMBL3431620 IC50 136.3 nM
CN1CCN(C(=O)COc2ccccc2)[C@@H](c2nc(-c3ccc4c(c3)CC(=O)N4)no2)C1 CHEMBL3431557 IC50 136.95 nM
Cc1cc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)no1 CHEMBL3431469 IC50 137.2 nM
Cc1ncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c(=O)[nH]1 CHEMBL3431910 IC50 139.6 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431595 IC50 139.7 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cc([N+](=O)[O-])[nH]n2)n1 CHEMBL3431750 IC50 140.2 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3[nH]c(=O)c(=O)[nH]c3c2)n1 CHEMBL3431653 IC50 140.4 nM
CS(=O)(=O)c1ccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431848 IC50 140.6 nM
COc1ccc(Cl)cc1CN1C(=O)COc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431625 IC50 141.6 nM
O=C1CCCN1c1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431716 IC50 141.9 nM
Nc1cncc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431906 IC50 143.85 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2cc(Cl)c(N3CCOCC3)cc2C1 CHEMBL3431735 IC50 144.8 nM
CCOc1ccc(C(=O)Nc2ccc(C(=O)O)c(F)c2)cc1N(CCS(=O)O)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431725 IC50 145.9 nM
CS(=O)(=O)Nc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431530 IC50 146.0 nM
COc1ccc(Cl)cc1CN1C(=O)OC(C)(C)c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431671 IC50 146.5 nM
COC(=O)[C@H]1CCCC[C@@H]1c1nc([C@H]2CCCCN2C(=O)COc2ccccc2)no1 CHEMBL3431476 IC50 147.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(F)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431511 IC50 150.0 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2ccncc2)n1 CHEMBL3431870 IC50 150.4 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCN(c2cccc(Cl)c2)CC1 CHEMBL3431777 IC50 151.2 nM
COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431551 IC50 152.1 nM
Cc1cc(C)cc(S(=O)(=O)n2ccc3ccc(C(=O)Nc4ccc(CC(=O)O)cc4)cc32)c1 CHEMBL3431686 IC50 152.1 nM
O=C(O)c1ccc(NC(=O)c2ccc(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)s2)cc1 CHEMBL3431564 IC50 152.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cc(F)c(F)cc2F)n1 CHEMBL3431489 IC50 153.4 nM
O=C1COc2cc(C#C[C@H]3CCCCN3C(=O)COc3ccccc3)ccc2N1 CHEMBL3431707 IC50 153.5 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc(Cl)nc2)n1 CHEMBL3431487 IC50 154.5 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2ccc(F)cc2)n1 CHEMBL3431874 IC50 155.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431621 IC50 155.5 nM
O=C(O)c1ccc(C(=O)Nc2nn(Cc3ccc(OC(F)F)cc3)c3ccc(F)cc23)cc1 CHEMBL3431532 IC50 155.7 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nnn(-c2ccccc2)n1 CHEMBL3431656 IC50 156.0 nM
Cn1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)n1 CHEMBL3431744 IC50 156.3 nM
COc1ccc(-n2nnc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431658 IC50 158.5 nM
COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL2216777 IC50 158.9 nM
O=C(COc1ccccc1)N1CCCCC1c1cc(-c2ccccc2)n[nH]1 CHEMBL3431584 IC50 159.0 nM
COC[C@@H]1CCN(NC(=O)c2cccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)c2)C1 CHEMBL3431570 IC50 159.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431471 IC50 159.5 nM
N#Cc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431571 IC50 160.6 nM
CCOc1ccc2c(c1)CN(C(=O)[C@H]1CCCCN1C(=O)COc1ccccc1)C2 CHEMBL3431736 IC50 161.2 nM
COc1ccc(Cl)cc1S(=O)(=O)c1c2cc(C(=O)Nc3ccccc3)ccc2nn1C CHEMBL3431787 IC50 162.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N(c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2)C(C)C CHEMBL3431920 IC50 163.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(-c3cnc[nH]3)cc2)no1 CHEMBL3431527 IC50 163.6 nM
COc1ccc(-c2noc(C3C[S+]([O-])CCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431607 IC50 163.7 nM
CC(=O)Nc1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)cc1 CHEMBL3431860 IC50 164.1 nM
N#Cc1ccc(C#C[C@H]2CCCCN2C(=O)COc2ccccc2)cc1 CHEMBL3431705 IC50 164.2 nM
CN(C)C(=O)c1ccc(-c2noc(C3C4CC4CN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431609 IC50 164.7 nM
O=C(COc1ccncc1)N1CCCC[C@@H]1c1nnc(-c2cccc(C(F)(F)F)c2)[nH]1 CHEMBL3431639 IC50 165.1 nM
COCCN(C)C(=O)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431618 IC50 165.3 nM
N#Cc1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)cn1 CHEMBL3431666 IC50 165.8 nM
COc1ccc(Cl)cc1S(=O)(=O)c1nn(C)c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 CHEMBL3431792 IC50 166.3 nM
Cc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)no1 CHEMBL3431746 IC50 166.4 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc3nccn3c2)no1 CHEMBL3431654 IC50 166.9 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCN(c2ncccn2)CC1 CHEMBL3431775 IC50 167.2 nM
O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1cccc(C(F)(F)F)c1)CC2 CHEMBL3431546 IC50 167.25 nM
NC(=O)c1cncc(-c2noc([C@H]3COCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431614 IC50 168.25 nM
CCN1C(=O)CC(C)(C)c2ccc(-c3nc([C@H]4CCCCN4C(=O)COc4ccccc4)no3)cc21 CHEMBL3431636 IC50 168.5 nM
CCn1cc(Sc2cc(Cl)ccc2OC)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL3431477 IC50 169.5 nM
COc1ccc(Cl)cc1Cn1ccc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431779 IC50 169.9 nM
COc1ccc(Cl)cc1S(=O)(=O)c1n[nH]c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431791 IC50 172.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(CCC(=O)O)cc3)cc21 CHEMBL3431661 IC50 174.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N(CCC(=O)O)c1cc(C(=O)Nc2ccccc2)cc2c1OCO2 CHEMBL3431928 IC50 175.0 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2ccccn2)n1 CHEMBL3431873 IC50 175.5 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cnc3ccccc3n2)n1 CHEMBL3431485 IC50 176.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3ncsc3c2)n1 CHEMBL3431488 IC50 177.1 nM
COc1ccc(Cl)cc1Cc1c[nH]c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 CHEMBL3431728 IC50 180.1 nM
CCCN(c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431890 IC50 180.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(C2CCCC2)n1 CHEMBL3431637 IC50 181.5 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCc2cccc(Cl)c2C1 CHEMBL3431729 IC50 182.3 nM
Cc1cc(C)cc(S(=O)(=O)N2CCc3ccc(C(=O)Nc4ccc(CC(=O)O)cc4)cc32)c1 CHEMBL3431690 IC50 186.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COCc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431648 IC50 186.7 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc3cnccc3n2)n1 CHEMBL3431493 IC50 187.6 nM
COc1ccc(Cl)cc1S(=O)(=O)c1cn(CSC)c2ccc(C(=O)Nc3ccccc3)cc12 CHEMBL3431828 IC50 187.8 nM
Cc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)[nH]n1 CHEMBL3431748 IC50 188.0 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(Cl)cc2)no1 CHEMBL3431523 IC50 189.8 nM
O=C(O)c1ccc(NC(=O)c2cccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c2)cc1 CHEMBL2216780 IC50 190.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C)c2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431899 IC50 190.1 nM
CC(=O)NCc1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431688 IC50 190.2 nM
CCCN(c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431889 IC50 190.8 nM
COC1CCC(c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)CC1 CHEMBL3431474 IC50 191.2 nM
Cc1cc(C(=O)Nc2ccc(-c3nnn[nH]3)cc2)nn1Cc1ccc(OC(F)F)cc1 CHEMBL3431580 IC50 191.7 nM
O=C1NCc2ccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 CHEMBL3431757 IC50 191.9 nM
O=C(O)COc1cccc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431901 IC50 195.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ccn(CC(=O)O)n2)cc2c1OCO2 CHEMBL3431881 IC50 196.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2ccc(C(F)(F)F)nc2)n1 CHEMBL3431490 IC50 197.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nnn(-c2ccc(F)cc2)n1 CHEMBL3431657 IC50 197.3 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCN(c2cc(Cl)cc(Cl)c2)CC1 CHEMBL3431776 IC50 198.1 nM
COc1ccc(Cl)cc1Sc1c[nH]c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3431907 IC50 200.3 nM
CC(=O)Nc1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)n(C)n2)c1 CHEMBL3431640 IC50 200.9 nM
CNC(=O)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431616 IC50 202.6 nM
COc1ccc(C)cc1S(=O)(=O)n1ccc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431682 IC50 202.6 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCS(=O)(=O)c2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431767 IC50 204.2 nM
CS(=O)(=O)c1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)c1 CHEMBL3431486 IC50 205.8 nM
COc1ccc(Cl)cc1S(=O)(=O)n1ccc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431681 IC50 206.0 nM
O=C(COc1ccccc1)N1CCCCC1c1ncc(-c2cccc([N+](=O)[O-])c2)s1 CHEMBL3431588 IC50 206.1 nM
O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1cccc(Cl)c1)CCO2 CHEMBL3431603 IC50 207.45 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431587 IC50 208.0 nM
O=C(Nc1ccc(-c2nnn[nH]2)cc1)c1nn(Cc2ccc(OC(F)F)cc2)c2ccc(F)cc12 CHEMBL3431538 IC50 209.9 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2cc(F)c(OC3CCOCC3)cc2C1 CHEMBL3431799 IC50 210.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431819 IC50 210.5 nM
O=C1Cc2ccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 CHEMBL3431545 IC50 210.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccn(CC(=O)O)n3)cc21 CHEMBL3431838 IC50 213.0 nM
O=C(COc1ccccc1)NS(=O)(=O)Cc1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)cc1 CHEMBL3431861 IC50 214.0 nM
O=C(c1nc([C@H]2CCCCN2C(=O)COc2ccccc2)no1)N1CCC(c2ccncc2)C1 CHEMBL3431743 IC50 216.0 nM
CCN(CC)C(=O)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431617 IC50 216.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(Cl)cc(C(=O)Nc3ccn(CC(=O)O)n3)cc21 CHEMBL3431927 IC50 218.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC(C(=O)O)Oc2ccc(C(=O)Nc3ccccc3F)cc21 CHEMBL3431784 IC50 218.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc2c1OCCO2 CHEMBL3431826 IC50 218.9 nM
COc1cccc2c1CCN(C(=O)[C@H]1CCCCN1C(=O)COc1ccccc1)C2 CHEMBL3431731 IC50 219.3 nM
COc1ccc(Cl)cc1CN1C(=O)CS(=O)(=O)c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 CHEMBL3431662 IC50 219.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CC[S+]([O-])c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431771 IC50 219.9 nM
CCOC(=O)C1CN(S(=O)(=O)c2cc(Cl)ccc2OC)c2cc(C(=O)Nc3cccc(F)c3)ccc2O1 CHEMBL3431781 IC50 220.6 nM
O=C(NCc1ccc(-c2nnn[nH]2)cc1)c1nn(Cc2ccc(OC(F)F)cc2)c2ccc(F)cc12 CHEMBL3431543 IC50 220.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1noc(-c2cc[nH]n2)n1 CHEMBL3431745 IC50 221.2 nM
Cc1cc(C)cc(S(=O)(=O)c2n[nH]c3ccc(C(=O)Nc4ccccc4)cc23)c1 CHEMBL3431840 IC50 221.5 nM
O=C1Nc2ccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)cc2CO1 CHEMBL3431755 IC50 222.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc([N+](=O)[O-])s2)no1 CHEMBL3431697 IC50 223.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N(c1cc(C(=O)Nc2nc(CC(=O)O)cs2)cc2c1OCO2)C(C)C CHEMBL3431892 IC50 223.7 nM
COc1ccc(C)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 CHEMBL3431676 IC50 223.8 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2cnccn2)n1 CHEMBL3431866 IC50 224.0 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCc2c(Cl)cccc2C1 CHEMBL3431730 IC50 224.5 nM
O=C(O)c1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431562 IC50 226.2 nM
COc1ccc(Cl)cc1S(=O)(=O)Nc1cccc(C#Cc2ccc(C(=O)O)cc2)c1 CHEMBL3431541 IC50 226.45 nM
Cc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)no2)n(C)n1 CHEMBL3431747 IC50 228.0 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2cc(F)c(N3CCOCC3)cc2C1 CHEMBL3431800 IC50 229.0 nM
O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(Cc2cccc(Cl)c2)C(=O)CS3(=O)=O)cc1 CHEMBL3431756 IC50 229.3 nM
N#Cc1cncc(-c2noc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431615 IC50 231.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)nc3)cc21 CHEMBL3431577 IC50 232.2 nM
COc1ccc(Cl)cc1CN(C(=O)C(C)C)c1cc(C(=O)Nc2nc(CC(=O)O)cs2)ccc1Cl CHEMBL3431818 IC50 236.4 nM
COc1ccc(C)cc1S(=O)(=O)N1CCc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431689 IC50 237.0 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCN(c2ccccn2)CC1 CHEMBL3431774 IC50 238.4 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(F)c(F)c2)n[nH]1 CHEMBL3431702 IC50 238.6 nM
NC(=O)c1ccc(-c2csc([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cc1 CHEMBL3431859 IC50 239.4 nM
CCCCCCCC[C@H]1OC(=O)C(CSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(N)cnnc43)[C@H](O)[C@@H]2OP(=O)(O)O)[C@@H]1C(=O)O CHEMBL2216769 IC50 240.0 nM
O=C(NCCO)c1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431569 IC50 242.0 nM
O=C(COc1ccccc1)N1CCCCC1c1ncc(-c2cccc([N+](=O)[O-])c2)o1 CHEMBL3431589 IC50 243.3 nM
COc1ccc(Cl)cc1CN1C(=O)OC(C)(C)c2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431668 IC50 244.6 nM
COc1ccc(Cl)cc1-c1csc([C@H]2CCCCN2C(=O)COc2ccccc2)n1 CHEMBL3431809 IC50 247.2 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431574 IC50 247.8 nM
O=C([O-])C1(C(F)(F)CCCCCOc2ccc(Cl)cc2)CO1 CHEMBL2216768 IC50 250.0 nM
COCCN(c1cc(C(=O)Nc2nc(CC(=O)O)cs2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431922 IC50 252.1 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCc2ccccc2C1 CHEMBL3431692 IC50 252.35 nM
Cc1cc(C)cc(S(=O)(=O)N2CCOc3ccc(C(=O)Nc4ccc(C(=O)O)c(F)c4)cc32)c1 CHEMBL3431604 IC50 252.5 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2cccc([N+](=O)[O-])n2)no1 CHEMBL3431598 IC50 254.2 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(OCC3CC3)cc2C1 CHEMBL3431738 IC50 259.4 nM
CC(=O)Nc1ccc(-c2noc([C@H]3CCCCN3C(=O)C#Cc3ccccc3)n2)cc1C(F)(F)F CHEMBL3431768 IC50 260.3 nM
NNC(=O)c1cccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431597 IC50 264.4 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccccc2)cs1 CHEMBL3431804 IC50 267.9 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ncc(C(=O)Nc3ccccc3)cc21 CHEMBL3431497 IC50 270.3 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431717 IC50 272.4 nM
O=C1CN(NC(=O)c2cccc(-c3n[nH]c([C@H]4CCCCN4C(=O)COc4ccccc4)n3)c2)C(=O)N1 CHEMBL3431599 IC50 272.5 nM
COc1ccc(Cl)cc1CN1C(=O)OC(C)(C)c2ccc(C(=O)Nc3nccs3)cc21 CHEMBL3431652 IC50 277.5 nM
O=C(COc1ccccc1)N1CCCCC1c1cc(=O)n(-c2ccc(F)cc2)[nH]1 CHEMBL3431590 IC50 281.5 nM
CCN(CC)C(=O)c1nc([C@H]2CCCCN2C(=O)COc2ccccc2)no1 CHEMBL3431695 IC50 282.7 nM
CCN(c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431885 IC50 284.7 nM
Nc1ccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cn1 CHEMBL3431683 IC50 286.5 nM
COc1ccc(-c2noc([C@H]3CCCCN3C(=O)C#Cc3ccccc3)n2)cc1 CHEMBL3431703 IC50 288.15 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCCc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431596 IC50 288.7 nM
Cc1nnsc1-c1noc([C@H]2CCCCN2C(=O)COc2ccccc2)n1 CHEMBL3431464 IC50 292.8 nM
COc1ccc(Cl)cc1CN1C(=O)OCc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431726 IC50 293.9 nM
O=C(O)c1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)cc1 CHEMBL3431876 IC50 295.5 nM
COC(=O)c1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)sc2C)c1 CHEMBL3431877 IC50 305.1 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2ccc(C(F)(F)F)nc2)n1 CHEMBL3431864 IC50 312.5 nM
O=C(c1nc([C@H]2CCCCN2C(=O)COc2ccccc2)no1)N1CCOCC1 CHEMBL3431742 IC50 315.1 nM
COCCN(c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431924 IC50 315.3 nM
CCCN(c1cc(C(=O)Nc2ccn(CC(=O)O)n2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431891 IC50 324.3 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C(F)F)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431929 IC50 325.1 nM
Nc1ccc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)cn1 CHEMBL3431684 IC50 325.3 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(-c2ccc(=O)[nH]c2)no1 CHEMBL3431559 IC50 325.4 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ncc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431501 IC50 328.2 nM
COc1ccc(Cl)cc1CN1C(=O)OC(C)(C)c2ccc(C(=O)Nc3ccc(CC(=O)O)c(Cl)c3)cc21 CHEMBL3431669 IC50 330.7 nM
CC(=O)Nc1ccc(F)c(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)c1 CHEMBL3431664 IC50 331.8 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(Cl)cc2C1 CHEMBL3431462 IC50 335.8 nM
COCCN(c1cc(C(=O)Nc2ccn(CC(=O)O)n2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431925 IC50 337.0 nM
CCN(c1cc(C(=O)Nc2ccn(CC(=O)O)n2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431887 IC50 339.1 nM
COC(=O)c1ccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)cc1 CHEMBL3431875 IC50 364.7 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCCc2ccc(C(=O)Nc3ccc(C(=O)O)c(Cl)c3)cc21 CHEMBL3431613 IC50 370.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(C)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431718 IC50 374.7 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCc2ccc(NC(=O)c3ccc(CC(=O)O)cc3)cc21 CHEMBL3431680 IC50 387.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc2c1OCO2 CHEMBL3431879 IC50 391.4 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(C2COc3ccccc3O2)n1 CHEMBL3431871 IC50 398.2 nM
O=C(Cn1cc(-c2ccccc2)c2ccccc21)Nc1ccc(C(=O)O)cc1 CHEMBL3431766 IC50 473.5 nM
O=C(COc1ccccc1)OCc1cc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)ccn1 CHEMBL3431862 IC50 502.6 nM
Cc1cc(-c2n[nH]c([C@H]3CCCCN3C(=O)COc3ccccc3)n2)n(C)n1 CHEMBL3431846 IC50 511.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(OC)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 CHEMBL3431894 IC50 529.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N1CCCc2ccc(Oc3ccc(CC(=O)O)cc3)cc21 CHEMBL3431722 IC50 550.2 nM
COCCN(c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC CHEMBL3431923 IC50 621.7 nM
O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCc2ccc([N+](=O)[O-])cc2C1 CHEMBL3431733 IC50 648.5 nM
COc1ccc2[nH]cc(C(=O)COc3ccncc3)c2c1 CHEMBL3431513 IC50 657.6 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(Cc2ccc(Cl)cc2)n1 CHEMBL3431867 IC50 725.1 nM
NS(=O)(=O)c1ccc2c(c1)CN(C(=O)[C@H]1CCCCN1C(=O)COc1ccccc1)CC2 CHEMBL3431732 IC50 824.1 nM
COc1ccc(Cl)cc1S(=O)(=O)N(c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc2c1OCO2)C(C)C CHEMBL3431893 IC50 889.9 nM
O=C(COc1ccccc1)N1CCCC[C@@H]1c1csc(-c2ccc(C(F)(F)F)cn2)n1 CHEMBL3431865 IC50 934.6 nM