O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1)c1ccncc1F CHEMBL3666849 IC50 20.37 nM
Cc1oncc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666859 IC50 20.79 nM
Cc1ccccc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1 CHEMBL3666871 IC50 22.96 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1)c1cccc(F)c1F CHEMBL3666861 IC50 32.59 nM
Cc1ncsc1NC(=O)c1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666854 IC50 34.11 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666857 IC50 35.72 nM
Cc1ccccc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 CHEMBL3666830 IC50 36.35 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1ccncc1F CHEMBL3666877 IC50 37.58 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1cccnc1 CHEMBL3666875 IC50 47.21 nM
Cc1ncsc1CNc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666852 IC50 48.02 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666858 IC50 48.17 nM
O=C(Cc1cccnc1)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666851 IC50 48.22 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1c(F)cccc1F CHEMBL3666874 IC50 50.58 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)F)cc1 CHEMBL3666881 IC50 52.62 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1ccccc1F CHEMBL3666872 IC50 60.0 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)c(F)c1 CHEMBL3639657 IC50 60.31 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 CHEMBL3666827 IC50 62.44 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1ccncc1 CHEMBL3666876 IC50 62.56 nM
Cc1oncc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666845 IC50 63.17 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1)c1c(Cl)cncc1Cl CHEMBL3666842 IC50 65.49 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1cccc(F)c1F CHEMBL3666873 IC50 70.32 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666844 IC50 72.03 nM
O=C(Nc1c(F)cccc1F)c1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1 CHEMBL3666878 IC50 72.11 nM
Cc1ncncc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666867 IC50 81.25 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1)c1c(F)cccc1F CHEMBL3666862 IC50 98.58 nM
O=C(Nc1c(F)cccc1F)c1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666869 IC50 99.71 nM
Cc1ccccc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666847 IC50 119.7 nM
O=C(Nc1c(F)cccc1F)c1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666855 IC50 123.8 nM
Cc1noc(C)c1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666846 IC50 124.5 nM
O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1c(Cl)cncc1Cl CHEMBL3666833 IC50 129.6 nM
O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1ccncc1 CHEMBL3666831 IC50 141.3 nM
O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)c(F)c1)c1c(F)cccc1F CHEMBL3666836 IC50 145.1 nM
Cc1ccccc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666860 IC50 147.2 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1 CHEMBL3666870 IC50 149.6 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1)c1ccncc1F CHEMBL3666865 IC50 159.1 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1)c1c(Cl)cncc1Cl CHEMBL3666866 IC50 159.3 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C3CC3)c(Cl)c2C2CC2)c(F)c1 CHEMBL3666839 IC50 181.1 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666843 IC50 183.6 nM
O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)c(F)c1)c1ccncc1 CHEMBL3666837 IC50 184.6 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)c(Cl)c2C2CC2)cc1 CHEMBL3666856 IC50 194.0 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1)c1cccnc1 CHEMBL3666863 IC50 205.7 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 CHEMBL3666828 IC50 206.7 nM
Cc1ncncc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)c(F)c1 CHEMBL3666838 IC50 223.5 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1)c1ccncc1 CHEMBL3666864 IC50 232.0 nM
O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1ccncc1F CHEMBL3666832 IC50 243.9 nM
O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1)c1ccncc1 CHEMBL3666848 IC50 254.7 nM
Cc1oncc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 CHEMBL3666829 IC50 256.1 nM
Cc1ncsc1NC(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666853 IC50 269.0 nM
O=C(Nc1cnc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1c(F)cccc1F CHEMBL3666879 IC50 295.4 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2CF)cc1 CHEMBL3666880 IC50 373.4 nM
O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)nc1)c1c(F)cccc1F CHEMBL3666841 IC50 436.1 nM
O=C(Cc1ccccc1)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 CHEMBL3666834 IC50 456.6 nM
Cc1ncncc1NC(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 CHEMBL3666868 IC50 600.3 nM
O=C(Cc1ccccn1)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 CHEMBL3666850 IC50 604.3 nM
Cc1ncsc1C(=O)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)c(N)c1 CHEMBL3666840 IC50 851.4 nM
O=C(Cc1ccccn1)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 CHEMBL3666835 IC50 968.1 nM