Cc1cc(/C=C/c2ccc3cc(N(C)C)ccc3[n+]2C)c(C)n1-c1ccccc1 CHEMBL1201303 Kd 1.0 nM
Cn1ncc(-c2nc(N[C@H]3CC[C@H](N)CC3)ncc2Cl)c1CC1CC1 CHEMBL4754493 IC50 5.3 nM
CN1CCC(F)(Cn2cnc(-c3ccc(F)cn3)c2-c2ccnc3[nH]ccc23)CC1 CHEMBL5303449 IC50 7.2 nM
NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccc(Cl)cc1Cl CHEMBL1965660 pKi 7.943 nM
NC(=O)c1cc2c(-c3ccc(Nc4nc5ccccc5o4)cc3)cnc(N)c2s1 CHEMBL1993904 pKi 7.943 nM
COc1cnc(-c2cnc3ccccc3c2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203552 IC50 9.0 nM
COc1ccc(C2=NNc3cccc4c(OC)ccc2c34)cc1OC CHEMBL1997335 pKi 12.59 nM
Nc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCNCC2)n1 CHEMBL274064 pKi 12.59 nM
CCC(CO)Nc1nc(Nc2cccc(-c3ccccn3)c2)c2ncn(C(C)C)c2n1 CHEMBL1080583 IC50 14.0 nM
CC[C@H](CO)Nc1nc(Nc2cccc(-c3ccccn3)c2)c2ncn(C(C)C)c2n1 CHEMBL215919 IC50 14.0 nM
NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccc(Cl)cc1F CHEMBL1981079 pKi 15.85 nM
NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1973720 pKi 15.85 nM
COc1cnc(NCc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203555 IC50 19.0 nM
O=C1NCCc2[nH]c(-c3ccncc3)cc21 CHEMBL225519 pKi 31.62 nM
O=C(NN=Cc1cc(Br)c(O)c(Br)c1)Nc1ccccc1 CHEMBL1983575 pKi 31.62 nM
COc1cnc(/C=C/c2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203553 IC50 33.0 nM
CNCC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1996980 pKi 39.81 nM
N#Cc1ccc2c(c1)C(c1ccc3c(n1)CCCC3O)C(=O)N2 CHEMBL1985681 pKi 39.81 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1081312 pKi 39.81 nM
CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010872 IC50 48.0 nM
NC1CCC(Nc2nccc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1966628 pKi 50.12 nM
O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21 CHEMBL1997129 pKi 50.12 nM
CCCCNC(=O)c1cn(C(CC)CC)c(=O)c2cc(OC)c(OC)cc12 CHEMBL1982700 pKi 50.12 nM
C#Cc1cn(C2CCCC2)c2ncnc(N)c12 CHEMBL1993877 pKi 50.12 nM
COc1cnc(Nc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203556 IC50 54.0 nM
OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1986943 pKi 63.1 nM
CCNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)n2)s1 CHEMBL1983715 pKi 63.1 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL10 Kd 75.0 nM
Nc1n[nH]c2nc(Nc3cccc(NC(=O)Nc4ccc(F)c(Cl)c4)c3)ncc12 CHEMBL2089212 IC50 78.0 nM
Fc1ccc(-c2nc3sccn3c2-c2ccncc2)cc1 CHEMBL2000508 pKi 79.43 nM
CN(C)CC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1982271 pKi 79.43 nM
CNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)s1 CHEMBL1999484 pKi 79.43 nM
COc1cnc(OCc2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203557 IC50 95.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 99.0 nM
Cc1cccc(-c2[nH]c(-c3ccnc(N)n3)cc2C(N)=O)c1C CHEMBL1964290 pKi 100.0 nM
CCc1nc(-c2cccc(C)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 CHEMBL363648 pKi 100.0 nM
Cn1cc(Nc2ncc(Br)c(Nc3ccccc3C(N)=O)n2)cn1 CHEMBL1994669 pKi 100.0 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2cccc(F)c2)n1 CHEMBL243298 pKi 100.0 nM
NC(=O)c1ccc(-c2nc(-c3ccccn3)c(-c3ccc4c(c3)OCO4)[nH]2)cc1 CHEMBL440084 pKi 100.0 nM
Fc1ccc(-c2nc3occn3c2-c2ccnc(NC3CCNCC3)n2)cc1 CHEMBL1971186 pKi 125.89 nM
Cc1cc(=O)n2ccc(CN(C)C)c(O)c2n1 CHEMBL1988581 pKi 125.89 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(Cl)c4)c3)cc12 CHEMBL1974870 pKi 125.89 nM
NC(=O)c1ccc2nc(-c3ccc([N+](=O)[O-])o3)cn2c1 CHEMBL1973359 pKi 125.89 nM
CC(C)(C)c1cc(NC(=O)Nc2cccc(Nc3ncc4c(N)n[nH]c4n3)c2)n[nH]1 CHEMBL2089214 IC50 142.0 nM
COc1cnc(COc2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203559 IC50 146.0 nM
CC(C)[C@H](N)C(=O)OC[C@H](O)CNc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1 CHEMBL2089036 IC50 150.0 nM
CC(C)CNC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL2006456 pKi 158.49 nM
Nc1ncnc2c1c(I)nn2C1CCC(O)CC1 CHEMBL1996791 pKi 158.49 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1ccc(F)cc1 CHEMBL1966204 pKi 158.49 nM
Fc1ccc(-c2nc3cnccn3c2-c2ccnc(NCC3CC3)n2)cc1 CHEMBL1990904 pKi 158.49 nM
COc1cnc(COc2ccc(F)cc2)cc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203561 IC50 174.0 nM
CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)cc3)nc(NC[C@@H](O)CO)nc21 CHEMBL2089032 IC50 180.0 nM
CCCCN(CCC#N)C(=O)c1ccc2nc(-c3n[nH]c4ccccc34)[nH]c2c1 CHEMBL1983348 pKi 199.53 nM
Cn1cc(Nc2ncc(Cl)c(Nc3ccccc3C(N)=O)n2)cn1 CHEMBL1984548 pKi 199.53 nM
NC1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1998432 pKi 199.53 nM
COc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3)nc12 CHEMBL2005792 pKi 199.53 nM
Clc1cc(-c2c[nH]c3ncccc23)cc(NCc2ccccc2)n1 CHEMBL1969588 pKi 199.53 nM
CC(C)(CO)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(CCN)nccn23)n1 CHEMBL1982383 pKi 199.53 nM
Nc1nc2ccc(Br)cc2c2nc(-c3ccco3)nn12 CHEMBL5186013 IC50 220.0 nM
CC(=O)c1c(-c2ccncc2)[nH]c(-c2ccncc2)c1C CHEMBL526901 Kd 225.0 nM
COc1cnc(COc2ccc(F)cc2F)cc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203562 IC50 225.0 nM
O=C(NCC(F)(F)F)c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)cs1 CHEMBL4569508 IC50 230.0 nM
CN(C)C(=O)c1ccc(N2CCCN(c3ccnc4sc(C(N)=O)c(N)c34)CC2)cc1 CHEMBL2348350 Kd 230.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 IC50 250.0 nM
C[C@@H](Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1 CHEMBL466496 IC50 250.0 nM
COc1cnc(COc2ccc(F)c(F)c2)cc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203563 IC50 251.0 nM
O=C1Nc2ccccc2C1=Cc1ccc[nH]1 CHEMBL1996176 pKi 251.19 nM
Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 CHEMBL482967 pKi 251.19 nM
Nc1ncnc2scc(-c3ccccc3)c12 CHEMBL1975212 pKi 251.19 nM
CN(C)C1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1969151 pKi 251.19 nM
NCCCOc1cc2c(c(-c3ccc(Nc4nc5ccccc5o4)cc3)c1)CNC2=O CHEMBL1975490 pKi 251.19 nM
CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3occn23)n1)c1ccccc1 CHEMBL1990288 pKi 251.19 nM
O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1[nH]c3ccc(O)cc3c21 CHEMBL379975 pKi 251.19 nM
N#Cc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1 CHEMBL1990162 pKi 251.19 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1ccccc1 CHEMBL1999931 pKi 251.19 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cccc(F)c1 CHEMBL2003638 pKi 251.19 nM
O=C(Nc1cnccn1)Nc1cccc2c(O)cccc12 CHEMBL1992371 pKi 251.19 nM
COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl CHEMBL288441 Kd 280.0 nM
NC(=O)c1ccc(-c2nc(-c3ccc4c(c3)OCCO4)c(-c3ccccn3)[nH]2)cc1 CHEMBL410456 IC50 300.0 nM
CCc1nccn2c(-c3ccnc(NCC(C)(C)O)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL2001547 pKi 316.23 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc([N+](=O)[O-])cc2)n1 CHEMBL242865 pKi 316.23 nM
Cc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccc(F)cc3)cc12 CHEMBL1972339 pKi 316.23 nM
CCN(C(C)=O)c1ccc(Nc2nc(NC3CC3)c3nc[nH]c3n2)cc1 CHEMBL2006564 pKi 316.23 nM
N#Cc1ccc2nc(N)n(-c3nccs3)c2c1 CHEMBL1988805 pKi 316.23 nM
Oc1c2ccccc2c2c3c(cccc13)N=N2 CHEMBL1725279 pKi 316.23 nM
CC(C)COc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3)nc12 CHEMBL1984842 pKi 316.23 nM
Oc1cc(O)cc(C=Cc2ccc(O)c(O)c2)c1 CHEMBL1972346 pKi 316.23 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccc(Cl)c(Cl)c4)c3)cc12 CHEMBL1991063 pKi 316.23 nM
Cn1c2c(c3ccc(Cl)c(Cl)c31)C(C#N)C1(CCNCC1)NC2=O CHEMBL1945559 IC50 330.0 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 Kd 360.0 nM
COc1cnc(COc2cc(F)c(F)cc2C)cc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203565 IC50 383.0 nM
CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)cc3)nc(N3C[C@H](O)C[C@H]3CO)nc21 CHEMBL2089034 IC50 390.0 nM
NC(=O)c1cc2c(-c3ccc(Br)cc3)cncc2s1 CHEMBL1978195 pKi 398.11 nM
CCc1c(-c2ccc(C(C)=O)cc2)[nH]c2nccnc12 CHEMBL1994555 pKi 398.11 nM
NCCNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL1972290 pKi 398.11 nM
Clc1cc(-c2c[nH]c3ncccc23)nc(NC2CCOCC2)n1 CHEMBL1980253 pKi 398.11 nM
Cc1nccn2c(-c3ccnc(NCCC(C)(C)O)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL1978200 pKi 398.11 nM
COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC CHEMBL1991078 pKi 398.11 nM
Cc1nn(C)c2sc(C(N)=O)c(N)c12 CHEMBL1996837 pKi 398.11 nM
Cc1nccn2c(-c3ccnc(NCC(C)(C)O)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL1996500 pKi 398.11 nM
CC(=O)N1CCC(Nc2nccc(-c3c(-c4ccc(F)cc4)nc4occn34)n2)CC1 CHEMBL1986781 pKi 398.11 nM
CCNC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1992220 pKi 398.11 nM
CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3cc[nH]c3n2)cc1 CHEMBL2006765 pKi 398.11 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 400.0 nM
[2H]C([2H])([2H])C1(C([2H])([2H])[2H])Cn2nc(-c3ccc(F)cn3)c(-c3ccnc4[nH]ncc34)c2CO1 CHEMBL5081774 IC50 410.0 nM
COc1cnc(COc2ccc(F)cc2C)cc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203564 IC50 442.0 nM
CC(C)CCN1c2nc(Nc3cc(F)c(O)c(F)c3)ncc2N(C)C(=O)C1C CHEMBL573107 IC50 450.0 nM
COc1nccc(-c2c(-c3ccc(F)cc3)ncn2[C@H]2CC[C@H](O)CC2)n1 CHEMBL97162 Ki 501.0 nM
NC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1983589 pKi 501.19 nM
CC(C)(CN)CNc1cc(-c2c[nH]c3ncccc23)cc(F)n1 CHEMBL1987261 pKi 501.19 nM
CC(C)Oc1nccn2c(-c3ccnc(NCC(C)(C)O)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL1984700 pKi 501.19 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 501.19 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3[nH]ncc3c2)n1 CHEMBL396523 pKi 501.19 nM
COc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCC(O)CC2)n1 CHEMBL256835 pKi 501.19 nM
COc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL1995832 pKi 501.19 nM
CSc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17370 pKi 501.19 nM
COc1ccc(-c2nc(-c3ccnc(N)n3)sc2C(N)=O)c(Cl)c1 CHEMBL3261517 IC50 545.0 nM
COc1cnc(CCc2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203554 IC50 568.0 nM
CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)cc3)nc(N[C@@H]3CCC[C@H](O)[C@@H]3O)nc21 CHEMBL2089033 IC50 600.0 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)NCC(F)(F)F)c4)cnn3c2)cn1 CHEMBL4550702 IC50 630.0 nM
CN1Cc2nccc(-c3cn(C)nc3-c3ccc(F)cc3)c2C1=O CHEMBL5303425 IC50 630.0 nM
COCCNc1nccc(-c2c(-c3ccc(F)cc3)nc3cnccn23)n1 CHEMBL1969372 pKi 630.96 nM
O=c1cc(-c2ccncc2)nc(NC2CCCCC2)[nH]1 CHEMBL1958401 pKi 630.96 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCCCCCCCCN)cnc(N)c34)cc2)c1 CHEMBL1978166 pKi 630.96 nM
CC(C)(O)CNc1nccc(-c2c(-c3ccc(F)cc3F)nc3c(CC4CC4)nccn23)n1 CHEMBL1994040 pKi 630.96 nM
O=C(Cc1cccs1)Nc1nc2ccccc2s1 CHEMBL1421720 pKi 630.96 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(OC(F)(F)F)c4)c3)cc12 CHEMBL1965836 pKi 630.96 nM
O=C1Nc2ccccc2C1=Cc1c[nH]c2ccccc12 CHEMBL1986590 pKi 630.96 nM
CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc21 CHEMBL406845 pKi 630.96 nM
Fc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL316264 pKi 630.96 nM
CNC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL2005509 pKi 630.96 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1 CHEMBL243088 pKi 630.96 nM
CS(=O)(=O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL280317 Ki 650.0 nM
CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)cc3)nc(NCC[C@H](O)CO)nc21 CHEMBL2089035 IC50 660.0 nM
NC(=O)c1sc(-c2ccnc(N)n2)nc1-c1ccc(Cl)cc1Cl CHEMBL3261514 IC50 694.0 nM
COc1cnc(CCc2ccc(F)cc2)cc1-c1cc2c([nH]1)CCNC2=O CHEMBL2203560 IC50 736.0 nM
C[C@@H](N)c1ccc(C(=O)Nc2ccnc3[nH]ccc23)cc1 CHEMBL571948 Kd apparent 766.0 nM
CC1(C)Cn2nc(-c3ccc(F)cn3)c(-c3ccnc4[nH]ncc34)c2CO1 CHEMBL5095777 IC50 790.0 nM
COCC(C)(C)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(C)nccn23)n1 CHEMBL1982563 pKi 794.33 nM
CCCCC(=O)Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL2006450 pKi 794.33 nM
CCC(=O)Nc1ccc(C(=O)N2CCNCC2)c(O)c1 CHEMBL1988141 pKi 794.33 nM
Cc1cccc(-c2c(-c3ccncc3)nc(NCC(N)Cc3ccccc3)n(C)c2=O)c1 CHEMBL1971430 pKi 794.33 nM
Clc1cc(Nc2nc(NC3CC3)c3sccc3n2)ccc1N1CCOCC1 CHEMBL2002586 pKi 794.33 nM
Cc1cn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3F)nc2c(C)n1 CHEMBL2000408 pKi 794.33 nM
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC CHEMBL1241473 pKi 794.33 nM
OCCCn1cnc(-c2ccccc2)c1-c1ccncc1 CHEMBL2002373 pKi 794.33 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 CHEMBL1967531 pKi 794.33 nM
O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 CHEMBL1973540 pKi 794.33 nM
CCc1nc(Nc2ccc(N3CCOCC3)c(Cl)c2)nc2[nH]ccc12 CHEMBL2004118 pKi 794.33 nM
Cc1nccn2c(-c3ccnc(NCC4(O)CC4)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL1965589 pKi 794.33 nM
COc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCNCC2)n1 CHEMBL95692 pKi 794.33 nM
Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 CHEMBL16687 IC50 820.0 nM
Nc1nc(N)c2nc(-c3cccc(O)c3)c(-c3cccc(O)c3)nc2n1 CHEMBL230011 Kd 830.0 nM
CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1N[C@H]1CC[C@H](CN(C)C)CC1 CHEMBL3688339 Kd apparent 931.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 970.0 nM
CNC(=O)c1nn(C)c2c1C(C)(C)Cc1cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc1-2 CHEMBL564829 Kd apparent 995.0 nM
CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1 CHEMBL296468 Kd 1000.0 nM
NC1CCCCC1Nc1nccc(-c2c[nH]c3ncccc23)n1 CHEMBL1995813 pKi 1000.0 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 CHEMBL244378 pKi 1000.0 nM
CC(C)(CO)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(OCC(F)(F)F)nccn23)n1 CHEMBL2001957 pKi 1000.0 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 1000.0 nM
Nc1nccc2cnc(-c3ccccc3)n12 CHEMBL1969156 pKi 1000.0 nM
Nc1ncnc2c1sc1ncnc(N)c12 CHEMBL1976090 pKi 1000.0 nM
O=C(Nc1nc2ccccc2n1CCCO)c1cccc([N+](=O)[O-])c1 CHEMBL210887 pKi 1000.0 nM
CC(C)Oc1cc(Nc2nc(NC(C)c3ccc(F)cn3)ncc2Cl)n[nH]1 CHEMBL2007421 pKi 1000.0 nM
CCCNC(=O)c1ccc(Nc2nc(CC)c3cc[nH]c3n2)cc1 CHEMBL1997007 pKi 1000.0 nM
Oc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL278041 pKi 1000.0 nM
Cc1cccc(Nc2nc(NC3CCCCC3N)cnc2C(N)=O)c1 CHEMBL1974328 pKi 1000.0 nM
CC(C)Oc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3F)nc12 CHEMBL2000429 pKi 1000.0 nM
CC(Nc1cncc(-n2cnc3ccc(C#N)cc32)n1)c1ccccc1F CHEMBL1977138 pKi 1000.0 nM
CN(C)CC(=O)NC1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1995712 pKi 1000.0 nM
N#Cc1cccc(NC(=O)Nc2ccnc3cc(C(F)(F)F)ccc23)n1 CHEMBL1968868 pKi 1000.0 nM
O=C1NCCc2[nH]c(-c3ccnc(-c4cnc5ccccc5c4)c3)cc21 CHEMBL226403 pKi 1000.0 nM
CC(C)(CN)CNc1nc(Cl)cc(-c2c[nH]c3ncccc23)n1 CHEMBL1968930 pKi 1000.0 nM
Cc1nc(COc2ccccc2Cl)sc1-c1ccnc(N)n1 CHEMBL1375640 pKi 1000.0 nM
COc1ccc(CNc2cc(-c3c[nH]c4ncccc34)cc(F)n2)cc1 CHEMBL1986855 pKi 1000.0 nM
O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1nc(C(=O)O)c(-c3ccc(CO)cc3)s1)CC2 CHEMBL1983980 pKi 1000.0 nM
COc1cc(OC)c(C=C2C(=O)Nc3ccccc32)c(OC)c1 CHEMBL576349 IC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM