COc1cccc(OC)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3913129 IC50 2.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(OCC(=O)C(C)(C)C)n(-c2ccccc2F)n1 CHEMBL2171390 IC50 3.0 nM
COc1ccc(C(C)(C)C#N)cc1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3947662 IC50 4.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(OC[C@H](O)C(C)(C)C)n(-c2ccccc2F)n1 CHEMBL2171392 IC50 5.0 nM
COc1cccc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3959487 IC50 5.0 nM
COc1cccc(OC)c1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3900996 IC50 5.0 nM
COc1cc(C)cc(OC)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3945914 IC50 6.0 nM
COc1cccc(OC)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3975529 IC50 7.0 nM
COc1cc(C)cc(OC)c1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3977104 IC50 8.0 nM
COc1cccc(F)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3944726 IC50 8.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(OC[C@@H](O)C(C)(C)C)n(-c2ccccc2F)n1 CHEMBL2171394 IC50 10.0 nM
COc1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3898095 IC50 10.0 nM
COc1ccc2c(c1-c1cc(C(CC(=O)O)c3nnc(C)o3)cc(C(F)(F)F)c1)OC(C)(C)C2 CHEMBL3920300 IC50 10.0 nM
COc1cccc(OC)c1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3907904 IC50 11.0 nM
COc1ccc(F)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3895656 IC50 12.0 nM
COc1ccccc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3985600 IC50 13.0 nM
COc1cc(CO)cc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3980117 IC50 14.0 nM
COc1ccc(OC)c(-c2cc(C(CC(=O)O)c3nnc(C)o3)cc(C(F)(F)F)c2)c1 CHEMBL3916226 IC50 14.0 nM
CCOc1ccccc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3946844 IC50 14.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(OCC2CC2)n(-c2ccccc2F)n1 CHEMBL2171398 IC50 15.0 nM
CCOc1cc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nn1-c1ccccc1F CHEMBL2171397 IC50 15.0 nM
COc1cccc(F)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3914540 IC50 16.0 nM
COc1cc(C)cc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3981058 IC50 16.0 nM
COc1cccc(OC)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3985437 IC50 17.0 nM
COc1ccc2c(c1-c1cc(Cl)cc(C(CC(=O)O)c3nnc(C)o3)c1)OC(C)(C)C2 CHEMBL3985175 IC50 17.0 nM
COc1ccc(C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3982519 IC50 17.0 nM
COc1ccc(C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3900002 IC50 17.0 nM
COc1ccc(C(C)(C)C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3942847 IC50 17.0 nM
COc1ccc(Cl)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3900041 IC50 17.0 nM
COc1cccc(Cl)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3969663 IC50 17.0 nM
COc1ccc(OC)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1OC CHEMBL3946014 IC50 18.0 nM
COc1ccc(O)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3901611 IC50 18.0 nM
COc1cccc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3902645 IC50 18.0 nM
COc1cc(C)cc(OC)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3941265 IC50 19.0 nM
COc1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3945253 IC50 21.0 nM
COc1ccc(CO)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3962665 IC50 22.0 nM
COc1ccc(-c2cc(C(CC(=O)O)c3nnc(C)o3)cc(C(F)(F)F)c2)c(OC)c1 CHEMBL3915744 IC50 23.0 nM
COc1ccc(C)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3953436 IC50 24.0 nM
COc1cc(C)cc(OC)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3893164 IC50 24.0 nM
CCOc1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3933072 IC50 24.0 nM
O=C(O)CC(NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1)c1ccc(-c2ccc(F)cc2)cc1 CHEMBL3145342 IC50 25.0 nM
COc1ccc(C(C)C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3985962 IC50 25.0 nM
COc1cc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nn1-c1ccccc1F CHEMBL2171396 IC50 26.0 nM
COc1ccc(C(C)C)cc1-c1cccc([C@@H](CC(=O)O)c2nnc(C)o2)c1 CHEMBL3908185 IC50 27.0 nM
COc1ccc(OC)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1 CHEMBL3935782 IC50 28.0 nM
COc1cc(C)cc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3891945 IC50 28.0 nM
COc1ccc(CO)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3889674 IC50 29.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(-c2cccc(C)c2C)n1 CHEMBL3682847 IC50 29.4 nM
COc1c(F)c(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nn1-c1ccccc1F CHEMBL2171399 IC50 30.0 nM
COc1cccc(OC)c1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3942531 IC50 30.0 nM
COc1ccc(C(C)C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3937024 IC50 31.0 nM
COc1ccc(-c2cc(Cl)cc(C(CC(=O)O)c3nnc(C)o3)c2)c(OC)c1 CHEMBL3930978 IC50 33.0 nM
COc1ccc(Cl)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3931996 IC50 34.0 nM
COc1ccc(C(C)(C)C)cc1-c1cccc([C@H](CC(=O)O)c2nccs2)c1 CHEMBL3945021 IC50 35.0 nM
COc1cc(F)ccc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3983446 IC50 35.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cccc(C)c1C CHEMBL3682898 IC50 37.0 nM
COc1ccc(F)c(F)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3962204 IC50 37.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1 CHEMBL3145341 IC50 38.0 nM
COc1ccc(F)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3979075 IC50 38.0 nM
COc1ccc(OC)c(-c2cccc(C(CC(=O)O)c3nnc(C)o3)c2)c1 CHEMBL3962185 IC50 41.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccccc1F CHEMBL3682944 IC50 41.8 nM
COc1cc(C)cc(OC)c1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3921654 IC50 44.0 nM
COc1ccc(C(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3928014 IC50 44.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(F)cc1F CHEMBL3687814 IC50 46.3 nM
CCOc1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3950022 IC50 47.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(Cl)c1F CHEMBL3682986 IC50 48.4 nM
COc1cc(C)cc(OC)c1-c1cccc(C(CC(=O)O)c2ncco2)c1 CHEMBL3937319 IC50 49.0 nM
COc1ccc(C(C)C)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3902520 IC50 49.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccc(F)cc1F CHEMBL3687790 IC50 49.1 nM
CC(C)(C)[C@@H](O)COc1cc(C(=O)N[C@@H](CC(=O)O)c2ccc(Cl)cc2Cl)nn1-c1ccccc1F CHEMBL2171393 IC50 50.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(-c2ccccc2Cl)n1 CHEMBL3678053 IC50 50.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(F)c1Cl CHEMBL3687834 IC50 50.65 nM
COc1ccc(C(C)(C)C)cc1-c1cccc([C@@H](CC(=O)O)c2ncco2)c1 CHEMBL3958275 IC50 51.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3900910 IC50 51.0 nM
COc1ccc(C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3895510 IC50 52.0 nM
COc1cccc(CO)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3978139 IC50 52.0 nM
COc1ccc(C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3957521 IC50 52.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(C)c1C CHEMBL3687927 IC50 52.8 nM
COc1ccc(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(OC)c1 CHEMBL3940536 IC50 53.0 nM
COc1cccc(Cl)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3926017 IC50 53.0 nM
COc1c(C)cccc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3948276 IC50 53.0 nM
COc1ccc(C(C)(C)C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3972672 IC50 55.0 nM
COc1ccc(OC)c(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)c1OC CHEMBL3913250 IC50 56.0 nM
COc1cccc(F)c1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3960856 IC50 56.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2Cl)[nH]1 CHEMBL3145343 IC50 57.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cc(F)ccc1F CHEMBL3687796 IC50 57.1 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2cccc(F)c2)[nH]1 CHEMBL3145344 IC50 59.0 nM
COc1ccc(C(C)(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3933390 IC50 59.0 nM
CC(C)(C)C(=O)COc1cc(C(=O)N[C@@H](CC(=O)O)c2ccc(Cl)cc2Cl)nn1-c1ccccc1F CHEMBL2171391 IC50 60.0 nM
COc1ccc(F)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3902133 IC50 60.0 nM
COc1ccc(C(C)(C)C)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3946210 IC50 61.0 nM
COc1ccccc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3976334 IC50 61.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1ccc(Cl)cc1 CHEMBL3687912 IC50 62.3 nM
CCOc1ccc(C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3968764 IC50 65.0 nM
Cc1nnc(C(CC(=O)O)c2cc(-c3ccccc3OC(F)(F)F)cc(C(F)(F)F)c2)o1 CHEMBL3893162 IC50 65.0 nM
COc1cc(C)cc(OC)c1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3931851 IC50 66.0 nM
COc1cccc(F)c1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3970901 IC50 67.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(C)c1Cl CHEMBL3687838 IC50 67.8 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccccc1F CHEMBL3682858 IC50 68.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cccc(Cl)c1Cl CHEMBL3682887 IC50 69.6 nM
CC(C)(C)[C@H](O)COc1cc(C(=O)N[C@@H](CC(=O)O)c2ccc(Cl)cc2Cl)nn1-c1ccccc1F CHEMBL2171395 IC50 70.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2)[nH]1 CHEMBL3145334 IC50 70.0 nM
COc1ccc(CO)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3914576 IC50 72.0 nM
COc1cccc(CO)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3890405 IC50 73.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(-c2ccccc2F)n1 CHEMBL3678054 IC50 73.3 nM
COc1ccc(F)cc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)ccc1OC CHEMBL3682969 IC50 73.7 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccccc1 CHEMBL3682995 IC50 75.1 nM
Cc1ccc(F)cc1C(CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1 CHEMBL3145345 IC50 76.0 nM
COc1cccc(Cl)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3984402 IC50 80.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1cccc(Cl)c1 CHEMBL3687913 IC50 80.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccccc1C CHEMBL3682869 IC50 81.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccoc1C CHEMBL3682987 IC50 81.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccccc1C CHEMBL3682935 IC50 81.9 nM
COc1ccccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)ccc1OC CHEMBL3683020 IC50 83.3 nM
COc1ccc(C)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3979982 IC50 85.0 nM
COc1ccc(C(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3971583 IC50 85.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3914904 IC50 85.0 nM
COc1ccc(C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3896890 IC50 86.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2ccc(F)cc2)[nH]1 CHEMBL3145347 IC50 87.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1nc(Cl)c(N)nc1N CHEMBL3687856 IC50 87.1 nM
Cc1nnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3OC(F)(F)F)c2)o1 CHEMBL3961052 IC50 89.0 nM
COc1ccc(Cl)cc1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3966754 IC50 89.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cccc(F)c1C CHEMBL3682918 IC50 90.1 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cccc(F)c1F CHEMBL3682893 IC50 90.2 nM
CCOc1ccccc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3946365 IC50 91.0 nM
COc1ccc(C(C)C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3964057 IC50 93.0 nM
COc1ccc(OC)c(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)c1 CHEMBL3918744 IC50 94.0 nM
Cc1ccc(F)cc1-c1cccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)n1 CHEMBL3682849 IC50 94.4 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccoc1C CHEMBL3687817 IC50 96.0 nM
COc1ccc(F)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3890675 IC50 96.0 nM
COc1cccc(Cl)c1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3957034 IC50 96.0 nM
COc1ccc(C(C)C)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3927665 IC50 97.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccccc1C(F)(F)F CHEMBL3687812 IC50 99.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cc(F)ccc1F CHEMBL3682894 IC50 99.8 nM
O=C(O)CC(NC(=O)c1cc(=O)n(-c2ccccc2)[nH]1)c1cccc(Cl)c1Cl CHEMBL3145346 IC50 100.0 nM
COc1cn(-c2ccccc2)nc1C(=O)N[C@@H](CC(=O)O)c1ccccc1C CHEMBL2171402 IC50 100.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2cccc(Cl)c2)[nH]1 CHEMBL3145349 IC50 102.0 nM
COc1ccccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)ccc1OC CHEMBL3682941 IC50 102.0 nM
COc1ccc(C(C)(C)C)cc1-c1cccc(C(CC(=O)O)c2ncco2)c1 CHEMBL3983512 IC50 103.0 nM
COc1cccc(C#N)c1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3919805 IC50 103.0 nM
COc1cccc(C#N)c1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3910045 IC50 104.0 nM
CCOc1ccccc1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3916666 IC50 104.0 nM
COc1cccc(Cl)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3985694 IC50 106.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1ccc(F)cc1 CHEMBL3687902 IC50 107.0 nM
COc1ccc(F)c(F)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3948362 IC50 107.0 nM
COc1cc(F)ccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)ccc1OC CHEMBL3687805 IC50 107.2 nM
COc1ccc(F)cc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)ccc1OC CHEMBL3687808 IC50 107.3 nM
COc1ccc(Cl)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3904246 IC50 108.0 nM
COc1cccc(F)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3943021 IC50 108.0 nM
COc1ccc(S(C)(=O)=O)cc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3953818 IC50 109.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1nn(-c2ccccc2)cc1O CHEMBL2171401 IC50 110.0 nM
COc1c(Cl)c(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nn1-c1ccccc1F CHEMBL2171400 IC50 110.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(Cl)c1C CHEMBL3687822 IC50 110.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccc(F)cc1C CHEMBL3687797 IC50 110.6 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cc(F)ccc1C CHEMBL3682904 IC50 111.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(Cl)c1Cl CHEMBL3682954 IC50 114.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccncc1F CHEMBL3687955 IC50 115.3 nM
COc1ccccc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3972624 IC50 116.0 nM
COc1cccc(F)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3909562 IC50 116.0 nM
COc1ccccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)ccc1OC CHEMBL3687780 IC50 116.1 nM
COc1cc(C(N)=O)ccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3984445 IC50 118.0 nM
COc1ccc(Cl)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3936456 IC50 118.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cc(C)ncc1F CHEMBL3687953 IC50 118.2 nM
COc1ccc(C(C)(C)C)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3910610 IC50 119.0 nM
COc1cc(F)ccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3920533 IC50 119.0 nM
COc1ccccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)ccc1OC CHEMBL3682874 IC50 119.1 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(C)c1Cl CHEMBL3682993 IC50 119.2 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cc(F)ccc1C CHEMBL3687804 IC50 119.3 nM
O=C(O)CC(NC(=O)c1cc(=O)n(-c2ccc(F)cc2F)[nH]1)c1cccc(Cl)c1Cl CHEMBL3145348 IC50 120.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccc(F)cc1F CHEMBL3682951 IC50 120.1 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cc(F)ccc1F CHEMBL3687943 IC50 121.0 nM
COc1ccc(OC)c(-c2cc(F)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1 CHEMBL3960402 IC50 122.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccccc1 CHEMBL3677990 IC50 123.1 nM
COc1ccc(C(C)(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3951783 IC50 124.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(-c2cc(F)ccc2F)n1 CHEMBL3682844 IC50 126.0 nM
COc1ccc(OC)c(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1 CHEMBL3981011 IC50 129.0 nM
COc1cc(F)ccc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3937502 IC50 129.0 nM
COc1ccc(S(C)(=O)=O)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 CHEMBL3908203 IC50 130.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(-c2ccccc2)n1 CHEMBL3678014 IC50 130.2 nM
COc1ccc(CO)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3903193 IC50 131.0 nM
COc1c(F)cc(F)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3946511 IC50 131.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(Cl)c1F CHEMBL3687831 IC50 131.4 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cccc(C)c1C CHEMBL3683032 IC50 131.8 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccccc1F CHEMBL3687783 IC50 132.0 nM
COc1ccc(C(C)C)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3901562 IC50 132.0 nM
COc1ccc(C(F)(F)F)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3964930 IC50 134.0 nM
COc1c(Cl)cccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3919517 IC50 134.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3cc(F)ccc3F)c2)s1 CHEMBL3935361 IC50 136.0 nM
COc1ccccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3927580 IC50 137.0 nM
COc1ccc(-c2cccc(C(CC(=O)O)c3nnc(C)o3)c2)c(OC)c1 CHEMBL3936394 IC50 137.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(C)c1C CHEMBL3687798 IC50 139.3 nM
COC(=O)c1ccc(OC)c(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1 CHEMBL3914964 IC50 140.0 nM
COc1ccc(OC)c(-c2cc(F)cc(C(CC(=O)O)c3ncco3)c2)c1 CHEMBL3918551 IC50 142.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1c(C)noc1C CHEMBL3682896 IC50 143.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccccc1C(F)(F)F CHEMBL3682871 IC50 145.7 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccccc1Cl CHEMBL3687782 IC50 147.0 nM
COc1ccc(C)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3956518 IC50 147.0 nM
CCOc1ccc(C)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3932488 IC50 147.0 nM
COc1ccc(O)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3915058 IC50 147.0 nM
COc1cccc(F)c1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3947854 IC50 148.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(F)c1C CHEMBL3682890 IC50 149.7 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(F)c1F CHEMBL3687795 IC50 150.5 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cccc(C)c1 CHEMBL3683021 IC50 152.0 nM
COc1ccccc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3970402 IC50 154.0 nM
COc1cccc(Cl)c1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3937834 IC50 155.0 nM
CCOc1ccc(C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3986611 IC50 155.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccc(F)cc1F CHEMBL3682884 IC50 155.6 nM
COc1ccc(F)c(F)c1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3970368 IC50 156.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1ccc(OCC(=O)C(C)(C)C)c(Br)n1 CHEMBL3687926 IC50 156.8 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cnccn1 CHEMBL3687827 IC50 158.8 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccccc1Cl CHEMBL3682876 IC50 159.0 nM
Cc1cccc([C@H](CC(=O)O)NC(=O)c2cccc(-c3ccccc3Cl)n2)c1 CHEMBL3687896 IC50 160.0 nM
COc1ccc(Cl)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3933069 IC50 160.0 nM
COc1ccc(F)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3938554 IC50 160.0 nM
COc1cccc(OC)c1-c1cncc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3936411 IC50 160.0 nM
Cc1cccc(-c2cccc(C(=O)N[C@@H](CC(=O)O)c3ccccc3C)n2)c1 CHEMBL3678052 IC50 160.8 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(Cl)cc1Cl CHEMBL3683013 IC50 161.0 nM
COc1c(C)cccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3937103 IC50 164.0 nM
COc1cccc(OC(C)C)c1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3977195 IC50 165.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3968528 IC50 165.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3897193 IC50 165.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cc(F)ccc1F CHEMBL3682957 IC50 171.0 nM
COc1cccc(F)c1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3909890 IC50 171.0 nM
COc1ccc(F)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3976652 IC50 174.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(F)cc1C CHEMBL3687815 IC50 176.8 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccccc1C(F)(F)F CHEMBL3682937 IC50 179.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccccc1 CHEMBL3682927 IC50 181.8 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3cccc(C)c3F)c2)s1 CHEMBL3925230 IC50 184.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccnc1OC CHEMBL3687950 IC50 185.0 nM
COc1ccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c(OC)c1 CHEMBL3944544 IC50 185.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1c(C)noc1C CHEMBL3683031 IC50 187.3 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(F)c1C CHEMBL3687823 IC50 192.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1ccccc1F CHEMBL3687891 IC50 195.0 nM
COc1ccc(C(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3900535 IC50 195.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3cccc(Cl)c3F)c2)s1 CHEMBL3956255 IC50 197.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccoc1C CHEMBL3687832 IC50 199.0 nM
COc1ccc(-c2cc(F)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(OC)c1 CHEMBL3959687 IC50 199.0 nM
O=C(O)CC(NC(=O)c1cc(=O)n(-c2ccccc2)[nH]1)c1ccc(Oc2ccccc2)cc1 CHEMBL3145350 IC50 200.0 nM
COc1cc(CO)ccc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3931333 IC50 201.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(Cl)c1C CHEMBL3682978 IC50 201.9 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cccc(Cl)c1C CHEMBL3682917 IC50 202.7 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(Cl)n1 CHEMBL3687851 IC50 204.9 nM
CCOc1ccccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3985787 IC50 209.0 nM
COc1cc(F)ccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)ccc1OC CHEMBL3683037 IC50 216.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3OC(F)(F)F)c2)s1 CHEMBL3906359 IC50 221.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3960561 IC50 222.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccccc1Cl CHEMBL3683022 IC50 223.0 nM
O=C(O)CC(NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1)c1ccccc1 CHEMBL3145351 IC50 226.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccccc1F CHEMBL3682877 IC50 228.0 nM
Cc1cnc(C(CC(=O)O)c2cccc(-c3cc(Cl)ccc3F)c2)s1 CHEMBL3963402 IC50 228.0 nM
Cc1nnc(C(CC(=O)O)c2cc(F)cc(-c3ccccc3OC(F)(F)F)c2)o1 CHEMBL3937009 IC50 231.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccccc1 CHEMBL3682861 IC50 232.0 nM
Cc1ccc(F)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1 CHEMBL3919773 IC50 232.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccc(F)c1F CHEMBL3682956 IC50 234.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(Cl)c1Cl CHEMBL3687793 IC50 235.2 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccc(F)cc1C CHEMBL3682897 IC50 239.0 nM
Cc1nnc(C(CC(=O)O)c2cccc(-c3ccccc3OC(F)(F)F)c2)o1 CHEMBL3960346 IC50 243.0 nM
COc1cc(F)ccc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3898087 IC50 246.0 nM
CC(=O)c1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3947559 IC50 250.0 nM
Cc1cccc([C@H](CC(=O)O)NC(=O)c2cc(=O)n(-c3ccccc3F)[nH]2)c1 CHEMBL3145340 IC50 252.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(F)c(F)c1 CHEMBL3683028 IC50 258.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cc(C)ccc1F CHEMBL3682977 IC50 262.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cc(Cl)ccc1F CHEMBL3639866 IC50 262.0 nM
COc1ccc(Cl)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3974490 IC50 262.0 nM
COc1ccc(S(C)(=O)=O)cc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3923928 IC50 265.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(F)cc1 CHEMBL3683015 IC50 267.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3936488 IC50 269.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1ccc(Cl)cc1Cl CHEMBL3687921 IC50 270.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cccc(-c2cccc(F)c2F)n1 CHEMBL3678063 IC50 272.0 nM
Cc1ccc([C@H](CC(=O)O)NC(=O)c2cc(=O)n(-c3ccccc3F)[nH]2)cc1 CHEMBL3145353 IC50 274.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1Cl CHEMBL3677992 IC50 274.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3926163 IC50 275.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cc(C)ccc1F CHEMBL3682916 IC50 278.0 nM
COc1ccc(CO)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3903583 IC50 284.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(C#N)cc1F CHEMBL3687818 IC50 288.0 nM
Cc1ccc(F)c(-c2cccc(C(=O)N[C@@H](CC(=O)O)c3ccccc3C)n2)c1 CHEMBL3682859 IC50 289.0 nM
COc1cccc(Cl)c1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3955435 IC50 292.0 nM
COc1cc(F)ccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)ccc1OC CHEMBL3682905 IC50 305.0 nM
COc1ccc(O)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3918909 IC50 307.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1cccc(C(F)(F)F)c1 CHEMBL3687923 IC50 315.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1ccc(Cl)cc1 CHEMBL3687905 IC50 322.0 nM
COc1cccc(CO)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3951633 IC50 325.0 nM
COc1ccc(-c2cc(F)cc(C(CC(=O)O)c3ncco3)c2)c(OC)c1 CHEMBL3962676 IC50 328.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3F)c2)s1 CHEMBL3910829 IC50 328.0 nM
COc1ccc(CO)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3946730 IC50 333.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cccc(C)c1 CHEMBL3687781 IC50 335.0 nM
COc1cc(F)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(F)c1 CHEMBL3935197 IC50 335.0 nM
COc1cc(F)ccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3940718 IC50 337.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1ccccc1F CHEMBL3687900 IC50 339.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1cccc(Cl)c1 CHEMBL3687904 IC50 339.0 nM
COc1cc(C)cc(OC)c1-c1cncc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3986087 IC50 343.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1ccccc1 CHEMBL3687876 IC50 345.0 nM
O=C(O)CC(NC(=O)c1cccc(-c2ccccc2Cl)n1)c1ccccc1Cl CHEMBL3687914 IC50 345.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cccnc1OC CHEMBL3687951 IC50 347.0 nM
COc1cc(OC)nc(Oc2cccnc2C(=O)N[C@@H](CC(=O)O)c2ccccc2C)n1 CHEMBL3677993 IC50 353.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3cccc(F)c3F)c2)s1 CHEMBL3983411 IC50 354.0 nM
COc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1 CHEMBL3145336 IC50 357.0 nM
COc1c(F)cc(F)cc1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3912590 IC50 367.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cc(C)ccc1F CHEMBL3687821 IC50 369.5 nM
O=C(O)C[C@H](NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1)c1ccccc1C(F)(F)F CHEMBL3145337 IC50 375.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cc(Cl)ccc1Cl CHEMBL3683030 IC50 385.0 nM
COc1cc(F)ccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)ccc1OC CHEMBL3682966 IC50 389.0 nM
COc1ccc(OC(F)(F)F)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3914447 IC50 389.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccc(F)cc1C CHEMBL3682959 IC50 394.0 nM
COc1cccc(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)c1F CHEMBL3894441 IC50 397.0 nM
COc1cccc(CO)c1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3921718 IC50 400.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3C(N)=O)c2)s1 CHEMBL3906345 IC50 404.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2Cl)n1)c1ccc(C(F)(F)F)cc1 CHEMBL3639867 IC50 406.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3cccc(OC(F)(F)F)c3)c2)s1 CHEMBL3943290 IC50 406.0 nM
CC(C)Oc1ccccc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3941398 IC50 409.0 nM
COc1c(C)cccc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3970269 IC50 410.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)cc1-c1ccccc1 CHEMBL3687893 IC50 414.0 nM
COc1cc(Cl)ccc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)ccc1OC CHEMBL3687806 IC50 415.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cc(C(F)(F)F)ccc1Cl CHEMBL3682889 IC50 421.0 nM
COc1cc(Cl)ccc1-c1cccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)n1 CHEMBL3682851 IC50 425.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1cccc(F)c1 CHEMBL3687890 IC50 429.0 nM
Cc1ccc(F)c(-c2cc(F)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1 CHEMBL3898572 IC50 437.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cc(Cl)ccc1F CHEMBL3682919 IC50 440.0 nM
COc1cccc(C#N)c1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3964382 IC50 446.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1ccc(-c2ccccc2)cn1 CHEMBL3678016 IC50 450.0 nM
COc1ccc(C(C)(C)C)cc1-c1cncc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3964068 IC50 452.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(C)cc1C CHEMBL3683034 IC50 457.0 nM
COc1c(F)cc(F)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3907664 IC50 457.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccncc3)c2)s1 CHEMBL3918895 IC50 459.0 nM
O=C(O)CC(NC(=O)c1cccc(Cl)n1)c1ccc(-c2ccccc2)cc1 CHEMBL3687842 IC50 463.0 nM
O=C(O)CC(c1cc(F)cc(-c2ccccc2OC(F)(F)F)c1)c1ncco1 CHEMBL3930877 IC50 466.0 nM
COc1cc(F)c(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)cc1F CHEMBL3934513 IC50 466.0 nM
COc1c(F)cc(F)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3904414 IC50 467.0 nM
Cc1cc(F)ccc1-c1cccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)n1 CHEMBL3682846 IC50 472.0 nM
COc1c(C)cccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3921281 IC50 474.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cc(F)ccc1C CHEMBL3682965 IC50 475.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cc(Cl)ccc1F CHEMBL3682979 IC50 481.0 nM
Cc1cccc(-c2cc(F)cc(C(CC(=O)O)c3ncco3)c2)c1F CHEMBL3969340 IC50 488.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cc(C)ccc1Cl CHEMBL3683043 IC50 497.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(Cl)cc1 CHEMBL3683016 IC50 501.0 nM
COc1cc(F)ccc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3932420 IC50 503.0 nM
COc1ccc(F)cc1-c1nc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)ccc1OC CHEMBL3682908 IC50 510.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1ccc(F)cc1 CHEMBL3687892 IC50 514.0 nM
COc1cccc(CO)c1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3894150 IC50 514.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cccc(Cl)c1 CHEMBL3683019 IC50 530.0 nM
COc1ccc(C(C)(C)C)cc1-c1cccc(C(CC(=O)O)c2nc(C)c(C)s2)c1 CHEMBL3912787 IC50 530.0 nM
COc1ccc([C@H](CC(=O)O)NC(=O)c2cccc(-c3ccccc3F)n2)cc1 CHEMBL3687898 IC50 540.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(Cl)cc2Cl)nc1-c1ccccc1 CHEMBL3677991 IC50 547.0 nM
Nc1nc(N)c(C(=O)NC(CC(=O)O)c2ccc(-c3ccccc3)cc2)nc1Cl CHEMBL3687860 IC50 563.0 nM
COc1ccc(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(F)c1 CHEMBL3919979 IC50 563.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1Br CHEMBL3678008 IC50 564.0 nM
Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3C#N)c2)s1 CHEMBL3891923 IC50 567.0 nM
COc1c(C)cccc1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3950579 IC50 571.0 nM
COc1ccc(F)c(-c2nc(C(=O)N[C@@H](CC(=O)O)c3ccccc3Cl)ccc2OC)c1 CHEMBL3687819 IC50 580.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1ccc(C)cc1 CHEMBL3683017 IC50 586.0 nM
COc1ccc(S(C)(=O)=O)cc1-c1cc(F)cc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3929123 IC50 588.0 nM
COc1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1F CHEMBL3937426 IC50 588.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccc(Cl)cc1Cl CHEMBL3682996 IC50 589.0 nM
COc1cc(Cl)ccc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3939137 IC50 590.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1cc(C(F)(F)F)ccc1F CHEMBL3687810 IC50 597.0 nM
O=c1oc(Cl)c(Cl)c2ccccc12 CHEMBL24983 IC50 600.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1ccc(F)nc1OC CHEMBL3687934 IC50 609.0 nM
COc1ccc(C#N)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3963004 IC50 618.0 nM
Cc1cnc(C(CC(=O)O)c2cccc(-c3ccccc3F)c2)s1 CHEMBL3889818 IC50 631.0 nM
Cc1nnc(C(CC(=O)O)c2cccc(-c3cccc(Cl)c3Cl)c2)o1 CHEMBL3942834 IC50 634.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1c(C)noc1C CHEMBL3682958 IC50 645.0 nM
Cc1cnc(C(CC(=O)O)c2cc(F)cc(-c3cc(F)ccc3F)c2)s1 CHEMBL3898140 IC50 649.0 nM
COc1cccc(C#N)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 CHEMBL3953900 IC50 652.0 nM
COc1ccc(Cl)cc1-c1cccc(C(CC(=O)O)c2nc(C)c(C)s2)c1 CHEMBL3940777 IC50 657.0 nM
COc1ncc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)cc1-c1ccccc1C CHEMBL3683051 IC50 702.0 nM
CC(=O)c1ccccc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 CHEMBL3974545 IC50 707.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cccc(F)c1 CHEMBL3682873 IC50 725.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cccnc1OC CHEMBL3687939 IC50 756.0 nM
Cn1nc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c2ccccc21 CHEMBL3905842 IC50 769.0 nM
Cc1cnc(C(CC(=O)O)c2cc(F)cc(-c3ccccc3F)c2)s1 CHEMBL3907160 IC50 780.0 nM
Cc1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1 CHEMBL3905558 IC50 784.0 nM
Cc1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1Cl CHEMBL3930073 IC50 797.0 nM
Cc1ccc(C)c(-n2[nH]c(C(=O)NC(CC(=O)O)c3ccc(-c4ccccc4)cc3)cc2=O)c1 CHEMBL3145338 IC50 803.0 nM
COc1ccc(F)c(-c2cccc(C(=O)N[C@@H](CC(=O)O)c3ccccc3C)n2)c1 CHEMBL3682852 IC50 815.0 nM
COc1c(Cl)cccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3977362 IC50 815.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cncc(-c2ccccc2Cl)c1 CHEMBL3678039 IC50 826.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(Sc2ncccn2)ccn1 CHEMBL3678013 IC50 844.0 nM
COc1c(C)cccc1-c1cccc(C(CC(=O)O)c2nccs2)c1 CHEMBL3931924 IC50 844.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccc(Cl)cc1Cl CHEMBL3682928 IC50 879.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1ccccc1C(F)(F)F CHEMBL3687917 IC50 880.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1cc(C(F)(F)F)ccc1Cl CHEMBL3682891 IC50 887.0 nM
O=C(O)C[C@H](NC(=O)c1cccc(-c2ccccc2F)n1)c1cccc(C(F)(F)F)c1 CHEMBL3687919 IC50 902.0 nM
Cc1ccc(F)c(-c2cc(F)cc(C(CC(=O)O)c3ncco3)c2)c1 CHEMBL3957465 IC50 903.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2Cl)nc1-c1ccc(F)cc1 CHEMBL3682998 IC50 909.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccc(C)cc2)nc1-c1cc(Cl)ccc1Cl CHEMBL3682895 IC50 910.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2F)nc1-c1ccccc1Cl CHEMBL3682943 IC50 917.8 nM
Cc1nnc(C(CC(=O)O)c2cccc(-c3ccccc3)c2)o1 CHEMBL3966115 IC50 935.0 nM
Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cncc(-c2cccc(Cl)c2Cl)c1 CHEMBL3678040 IC50 950.0 nM
COc1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1OC CHEMBL3903931 IC50 950.0 nM
COc1ccc(-c2cccc(Cl)c2F)cc1C(CC(=O)O)c1ncc(C)s1 CHEMBL3916708 IC50 954.0 nM
COc1cc(C(N)=O)ccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 CHEMBL3948126 IC50 960.0 nM
COc1cc(C(F)(F)F)ccc1-c1cccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)n1 CHEMBL3682850 IC50 963.0 nM
O=C(O)CC(c1cccc(-c2cccc(Cl)c2)c1)c1nccs1 CHEMBL3962006 IC50 967.0 nM
COc1ccc(-c2ccc(C)cc2F)cc1C(CC(=O)O)c1ncc(C)s1 CHEMBL3900047 IC50 970.0 nM
COc1ccc(-c2cc(F)ccc2F)cc1C(CC(=O)O)c1ncc(C)s1 CHEMBL3976385 IC50 975.0 nM
Cc1cnc(C(CC(=O)O)c2cc(F)cc(-c3cccc(OC(F)(F)F)c3)c2)s1 CHEMBL3930815 IC50 975.0 nM
COc1ccc(C(=O)N[C@@H](CC(=O)O)c2ccccc2C)nc1-c1cccc(C(F)(F)F)c1 CHEMBL3683012 IC50 981.0 nM
O=C(O)CC(c1cccc(-c2ccc3c(c2)OCCO3)c1)c1nccs1 CHEMBL3928417 IC50 987.0 nM
COc1ccc(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)c(F)c1 CHEMBL3983365 IC50 989.0 nM