CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL216981 IC50 0.049 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccco1 CHEMBL218115 Kd 0.049 nM
C[C@@H](C(=O)[N-]S(C)(=O)=O)c1ccc(OS(=O)(=O)C(F)(F)F)cc1 CHEMBL4442431 IC50 0.1 nM
CCN(CC)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O CHEMBL577075 IC50 0.12 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(C#N)c(S(=O)(=O)C(C)(C)CC(F)(F)F)c1O CHEMBL4066904 pIC50 0.1585 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(F)CCOCC2)c1O CHEMBL4098864 pIC50 0.1995 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(C#N)c(S(=O)(=O)C(C)(C)C)c1O CHEMBL4082136 pIC50 0.1995 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 0.24 nM
C[C@@H](Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1)[C@@H](O)CO CHEMBL4562140 pKi 0.2455 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@@H]2CC[C@@H](O)C2)c1O CHEMBL4072270 pIC50 0.2512 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)C2COC2)c1O CHEMBL4062361 pIC50 0.2512 nM
CC(C)(CCO)S(=O)(=O)c1c(Cl)ccc(NC(=O)N[C@@H]2CCC=C2Cl)c1O CHEMBL4060139 pIC50 0.2512 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCC2)c1O)Nc1cccc(F)c1Cl CHEMBL3818984 pIC50 0.3162 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCCC2)c1O)Nc1cccc(F)c1Cl CHEMBL3818853 pIC50 0.3162 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCCCC2)c1O)Nc1cccc(F)c1Cl CHEMBL3819480 pIC50 0.3162 nM
CCC1(S(=O)(=O)c2c(Cl)ccc(NC(=O)N[C@@H]3CCC=C3C)c2O)CCOCC1 CHEMBL4077201 pIC50 0.3162 nM
CN1CC2(CC(S(=O)(=O)c3c(Cl)ccc(NC(=O)Nc4cccc(F)c4Cl)c3O)C2)C1 CHEMBL3819163 pIC50 0.3981 nM
CN1CCC2(CCC(S(=O)(=O)c3c(Cl)ccc(NC(=O)Nc4cccc(F)c4Cl)c3O)CC2)CC1 CHEMBL3818581 pIC50 0.3981 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O CHEMBL3817901 pIC50 0.3981 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCN(C3CCC3)CC2)c1O CHEMBL4070506 pIC50 0.3981 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(F)F)c1O CHEMBL4086957 pIC50 0.3981 nM
CC1=CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)C)c1O CHEMBL4066818 pIC50 0.3981 nM
CCS(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(Cl)c2Cl)c1O CHEMBL3819295 pIC50 0.5012 nM
CC(C)(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O CHEMBL3819569 pIC50 0.5012 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCOC2)c1O)Nc1cccc(Cl)c1Cl CHEMBL3818793 pIC50 0.5012 nM
CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3819512 pIC50 0.5012 nM
CN1CC[C@H](S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)C1 CHEMBL3818277 pIC50 0.5012 nM
CN1CCC[C@H](S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3818827 pIC50 0.5012 nM
O=C(Nc1ccc(Cl)c(C(=O)N2CCCCC2)c1O)Nc1cccc(F)c1Cl CHEMBL3819221 pIC50 0.5012 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(C)CCOCC2)c1O CHEMBL4066510 pIC50 0.5012 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)C2CCOCC2)c1O CHEMBL4088551 pIC50 0.5012 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)C(F)(F)F)c1O CHEMBL4103349 pIC50 0.5012 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2(F)CCOCC2)c1O)N[C@@H]1CCC=C1Cl CHEMBL4082031 pIC50 0.5012 nM
CCC(C)c1coc([C@@H](CC)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)c1 CHEMBL396573 Ki 0.6 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)N2CCNCC2)c1O)Nc1cccc(Cl)c1Cl CHEMBL3818458 pIC50 0.631 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(Cl)c2Cl)c1O CHEMBL3818216 pIC50 0.631 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCN(CCF)CC2)c1O CHEMBL4098979 pIC50 0.631 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)CF)c1O CHEMBL4079102 pIC50 0.631 nM
C[C@@H](C(=O)NS(C)(=O)=O)c1ccc(OS(=O)(=O)C(F)(F)F)cc1 CHEMBL189475 IC50 0.7 nM
CN1CCN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)CC1 CHEMBL3819542 pIC50 0.7943 nM
CN1CCN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3818917 pIC50 0.7943 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCOCC2)c1O)Nc1cccc(Cl)c1Cl CHEMBL3818820 pIC50 0.7943 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(F)CCOC2)c1O CHEMBL4089421 pIC50 0.7943 nM
CCC(CC)c1coc([C@@H](CC)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)c1 CHEMBL246318 Ki 0.8 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL397237 pA2 1.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C(C)C)co1 CHEMBL246108 Ki 1.0 nM
CCc1coc([C@@H](CC)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)c1 CHEMBL245699 Ki 1.0 nM
Cc1cc(F)cc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)C)c1 CHEMBL254175 Ki 1.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)sc12 CHEMBL446458 IC50 1.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)cnc12 CHEMBL256668 IC50 1.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2F)nc2[nH]c(=O)sc12 CHEMBL403225 IC50 1.0 nM
CC(C)Cc1ccc([C@@H](C)C(=O)NS(C)(=O)=O)cc1 CHEMBL191413 IC50 1.0 nM
CCN1CCN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3819382 pIC50 1.0 nM
O=C(Nc1ccc(Cl)c(C(=O)N2CCCC2)c1O)Nc1cccc(F)c1Cl CHEMBL3818323 pIC50 1.0 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CC3(COC3)C2)c1O CHEMBL4076053 pIC50 1.0 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@@]2(C)CCOC2)c1O CHEMBL4067429 pIC50 1.0 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@]2(C)CCOC2)c1O CHEMBL4100674 pIC50 1.0 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2C[C@H](N3CCCC3)C2)c1O CHEMBL4076428 pIC50 1.0 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2C[C@H](N(C)C)C2)c1O CHEMBL4097602 pIC50 1.0 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)C)c1O CHEMBL4095602 pIC50 1.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCC=C2Cl)c1O CHEMBL4094324 pIC50 1.0 nM
CCN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3818331 pIC50 1.259 nM
CN1CC[C@H](S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)C1 CHEMBL3818179 pIC50 1.259 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(C)CCOC2)c1O CHEMBL4062546 pIC50 1.259 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(CF)CCOCC2)c1O CHEMBL4079718 pIC50 1.259 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)[C@@H]2CCOC2)c1O CHEMBL4076478 pIC50 1.259 nM
COCC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)N[C@@H]2CCC=C2C)c1O CHEMBL4084077 pIC50 1.259 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)CCNC(=O)OC(C)(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5421394 pKi 1.349 nM
COc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)C)cc1F CHEMBL402965 Ki 1.5 nM
CC(C)N1CCN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3819603 pIC50 1.585 nM
CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)CC1 CHEMBL3819521 pIC50 1.585 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCCOC2)c1O CHEMBL4081963 pIC50 1.585 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)(C)[C@H]2CCOC2)c1O CHEMBL4084135 pIC50 1.585 nM
CC1=C(F)CCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)C)c1O CHEMBL4098536 pIC50 1.585 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(F)cc(C#N)c1 CHEMBL404074 Ki 1.7 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(F)cc(F)c1 CHEMBL254775 Ki 1.7 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)cc(C#N)c1 CHEMBL254176 Ki 1.9 nM
CC(C)[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(F)cc(F)c1 CHEMBL404918 Ki 1.9 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCCNC2)c1O CHEMBL3039531 pKi 1.95 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1 CHEMBL3403850 pA2 1.995 nM
NS(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(Cl)c2Cl)c1O CHEMBL3819292 pIC50 1.995 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O)Nc1cccc(Cl)c1Cl CHEMBL3818269 pIC50 1.995 nM
CN1CCC2(CC1)CC(S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c1O)C2 CHEMBL3819070 pIC50 1.995 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(C)CCCOC2)c1O CHEMBL4060060 pIC50 1.995 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(F)(F)CN(C)C)c1O CHEMBL4072010 pIC50 1.995 nM
CN(C)C(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/c2ccccc2)c1O CHEMBL211468 IC50 2.0 nM
CN(C)C(=O)c1cc(Cl)cc(/N=c2\c(O)c(O)\c2=N/c2ccccc2)c1O CHEMBL387431 IC50 2.0 nM
CC(C)c1coc([C@@H](C)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)c1 CHEMBL246941 Ki 2.0 nM
CCCCc1coc([C@@H](CC)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)c1 CHEMBL246106 Ki 2.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(Br)co1 CHEMBL401939 IC50 2.0 nM
COC(=O)c1nc2c(N[C@H](C)CO)nc(SCc3cccc(F)c3F)nc2[nH]c1=O CHEMBL272105 IC50 2.0 nM
C[C@H](CO)Nc1nc(SCc2ccccc2F)nc2[nH]c(=O)sc12 CHEMBL271012 IC50 2.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccco3)C(F)(F)F)c(=O)c2=O)c1O CHEMBL473959 Ki 2.0 nM
CC(C)c1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(F)F)c1 CHEMBL523769 Ki 2.0 nM
CC[C@@H](Nc1c(Nc2ccc(Cl)c(S(=O)(=O)N(C)OC)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL4465379 IC50 2.0 nM
CC[C@@H](Nc1c(Nc2ccnc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL4574181 IC50 2.0 nM
CN(C)C(=O)c1cccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O CHEMBL5276296 IC50 2.0 nM
N#Cc1ccc(NC(=O)Nc2ccccc2Br)c2nn[nH]c12 CHEMBL38182 pKi 2.089 nM
CN(C)C(=O)c1cccc(Nc2n[s+]([O-])nc2N[C@@H](c2ccco2)C(C)(C)C)c1O CHEMBL403547 Ki 2.3 nM
Cc1ccc([C@@H](C)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)o1 CHEMBL216602 IC50 2.4 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(Cl)c2F)n1 CHEMBL3403851 pIC50 2.512 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCN(CC(F)F)CC2)c1O CHEMBL4076676 pIC50 2.512 nM
Cc1cc([C@H](Nc2n[s+]([O-])nc2Nc2cccc(C(=O)N(C)C)c2O)C(C)C)oc1C CHEMBL254943 Ki 2.7 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(CO)o1 CHEMBL427888 IC50 2.8 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)cc(F)c1 CHEMBL254174 Ki 2.8 nM
N#Cc1ccc(Nc2c(O)c(=O)/c2=N\c2ccccc2)c(O)c1 CHEMBL209859 IC50 3.0 nM
CC(C)c1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2CC2)c1 CHEMBL247150 Ki 3.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C2CCCC2)co1 CHEMBL246731 Ki 3.0 nM
CC[C@@H](Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)c1ccc(C)o1 CHEMBL253306 Ki 3.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2F)nc2nc(N)sc12 CHEMBL429791 IC50 3.0 nM
CC[C@@H](Nc1c(Nc2cc(C#N)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL560089 Ki 3.0 nM
CC1=C(Cl)CCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)C)c1O CHEMBL4071499 pIC50 3.162 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccn1 CHEMBL269707 IC50 3.3 nM
CCC(CC)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O CHEMBL218964 pKi 3.311 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccsc1 CHEMBL401940 IC50 3.4 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc2ccccc2o1 CHEMBL251811 IC50 3.5 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2CC2)o1 CHEMBL216603 IC50 3.6 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(C)C)o1 CHEMBL376414 IC50 3.8 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(Cl)co1 CHEMBL253714 IC50 3.8 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCOCC2)nc(SCc2cccc(F)c2F)n1 CHEMBL3403854 pIC50 3.981 nM
C[C@@H]1CN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)C[C@H](C)O1 CHEMBL3819013 pIC50 3.981 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(C)CCN(C3CCC3)CC2)c1O CHEMBL4092148 pIC50 3.981 nM
CC(C)(CO)S(=O)(=O)c1c(Cl)ccc(NC(=O)N[C@@H]2CCC=C2Cl)c1O CHEMBL4089896 pIC50 3.981 nM
CN(C)S(=O)(=O)c1c(F)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O CHEMBL375393 IC50 4.0 nM
CC(C)c1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(C)C)c1 CHEMBL247356 Ki 4.0 nM
CC(C)c1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)C)c1 CHEMBL247149 Ki 4.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C2CCCCC2)co1 CHEMBL246733 Ki 4.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C(C)(C)C)co1 CHEMBL394899 Ki 4.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)co1 CHEMBL245501 Ki 4.0 nM
CN(C)C(=O)c1cccc(Nc2n[s+]([O-])nc2N[C@@H](c2ccccc2)C(C)(C)C)c1O CHEMBL253305 Ki 4.0 nM
O=C(NCCc1c(-c2ccc(F)cc2)[nH]c2ccc(Br)cc12)NS(=O)(=O)c1ccccc1 CHEMBL254773 IC50 4.0 nM
Cc1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)[C@H](C)F)c1 CHEMBL516184 Ki 4.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(F)(F)C(F)(F)F)o1 CHEMBL523645 Ki 4.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL254370 Ki 4.0 nM
CC[C@@H](Nc1c(Nc2ccc(Br)c(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL557466 Ki 4.0 nM
O=C(Nc1ccc(F)cc1)c1cnc(N(Cc2ccccc2)Cc2ccc(B(O)O)cn2)nc1 CHEMBL3609018 IC50 4.0 nM
CC1CN(S(=O)(=O)Nc2cc(O[C@H](C)[C@@H](O)CO)nc(SCc3ccc(F)cc3)n2)C1 CHEMBL5095217 IC50 4.0 nM
CCc1ccc(C(CC)Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)o1 CHEMBL252852 IC50 4.1 nM
CC(C)C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)sc12 CHEMBL2349306 Ki 4.1 nM
Cc1cc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)C)cc(C(F)(F)F)c1 CHEMBL254982 Ki 4.4 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(Cl)co1 CHEMBL253497 IC50 4.5 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3cc(F)cc(F)c3)C3CC3)c(=O)c2=O)c1O CHEMBL254776 Ki 4.5 nM
CC[C@@H](Nc1c(Nc2c(C)ccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL562781 Ki 4.5 nM
C[C@H](CO)Nc1nc(SCc2ccccc2)nc2[nH]c(=O)sc12 CHEMBL402986 IC50 4.5 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(Cl)o1 CHEMBL404490 IC50 4.6 nM
CN(C)C(=O)c1cccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc3c(c2)OCO3)C(C)(C)C)c1O CHEMBL253495 Ki 4.7 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(Br)o1 CHEMBL253050 IC50 4.7 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(Cl)o1 CHEMBL253051 IC50 4.8 nM
CC[C@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5424054 pKi 4.898 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccc(F)c1 CHEMBL401512 IC50 4.9 nM
CCC(CC)/N=c1\c(O)c(O)\c1=N/c1cccc(C(=O)N(C)C)c1O CHEMBL214047 IC50 5.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc2c(c1)OCO2 CHEMBL220182 IC50 5.0 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O CHEMBL218387 IC50 5.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)s1 CHEMBL415446 Ki 5.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)cs1 CHEMBL393900 Ki 5.0 nM
Cc1ccc([C@H](Nc2n[s+]([O-])nc2Nc2cccc(C(=O)N(C)C)c2O)C(C)(C)C)o1 CHEMBL403206 Ki 5.0 nM
CC[C@@H](Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)c1ccccc1 CHEMBL253304 Ki 5.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccco1 CHEMBL252851 IC50 5.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(Br)co1 CHEMBL253498 IC50 5.0 nM
CN(C)S(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(C#N)cc12 CHEMBL403313 IC50 5.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(NS(C)(=O)=O)sc12 CHEMBL429682 IC50 5.0 nM
C[C@H](CO)Nc1nc(SCc2ccco2)nc2[nH]c(=O)sc12 CHEMBL272705 IC50 5.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(F)(F)F)o1 CHEMBL515262 Ki 5.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@H](CC(F)(F)F)c3ccco3)c(=O)c2=O)c1O CHEMBL473145 Ki 5.0 nM
CCC(F)(F)[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL523437 Ki 5.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3cc(Cl)c(Cl)o3)C(F)(F)F)c(=O)c2=O)c1O CHEMBL523807 Ki 5.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3cc(Cl)co3)C(F)(F)F)c(=O)c2=O)c1O CHEMBL491135 Ki 5.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc4c(c3)OCO4)C(F)(F)F)c(=O)c2=O)c1O CHEMBL518857 Ki 5.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCCC3C(=O)O)c2O)c(=O)c1=O)c1ccccc1 CHEMBL556862 Ki 5.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 CHEMBL385715 Ki 5.0 nM
CC[C@@H](Nc1c(Nc2cc(C#N)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 CHEMBL563875 Ki 5.0 nM
O=C(Nc1cccnc1Cl)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCCNC2)c1O CHEMBL3949893 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCCNC2)c1O)Nc1cccc(F)c1Cl CHEMBL3960024 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@@H]2C[C@H]3CC[C@@H](C2)N3C)c1O CHEMBL3941989 IC50 5.0 nM
O=C(Nc1ccccc1OC(F)(F)F)Nc1ccc(Cl)c(S(=O)(=O)CC2CCNC2)c1O CHEMBL3950351 IC50 5.0 nM
O=C(Nc1cccnc1Cl)Nc1ccc(Cl)c(S(=O)(=O)C2CNC2)c1O CHEMBL3953055 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)CC2CCNC2)c1O CHEMBL3946021 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CNC2)c1O)Nc1cccc(F)c1Cl CHEMBL3952713 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CNC2)c1O CHEMBL3901031 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)CC2CCNC2)c1O)Nc1cccc(F)c1Cl CHEMBL3910854 IC50 5.0 nM
CCc1ccccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O CHEMBL3926993 IC50 5.0 nM
O=C(Nc1cccnc1Cl)Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O CHEMBL3929680 IC50 5.0 nM
O=C(Nc1ccccc1OC(F)(F)F)Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O CHEMBL3951311 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O CHEMBL3953988 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O)Nc1cccc(F)c1Cl CHEMBL3906495 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O)Nc1cccc(Cl)c1Cl CHEMBL3916281 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O)Nc1cccc(F)c1Cl CHEMBL3967642 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O CHEMBL3970321 IC50 5.0 nM
O=C(Nc1ccccc1OC(F)(F)F)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O CHEMBL3927944 IC50 5.0 nM
CCc1ccccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O CHEMBL3930695 IC50 5.0 nM
O=C(Nc1cccnc1Cl)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O CHEMBL3892206 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O)Nc1cccc2c1OC(F)(F)O2 CHEMBL3892666 IC50 5.0 nM
O=C(Nc1cccnc1Cl)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCNC2)c1O CHEMBL3973880 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCNC2)c1O CHEMBL3971309 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCNC2)c1O)Nc1cccc(F)c1Cl CHEMBL3912983 IC50 5.0 nM
O=C(Nc1ccccc1Oc1ccccc1)Nc1ccc(Cl)c(S(=O)(=O)[C@H]2CCNC2)c1O CHEMBL3910320 IC50 5.0 nM
CCOC(=O)N1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3ccccc3Oc3ccccc3)c2O)CC1 CHEMBL3957549 IC50 5.0 nM
O=C(Nc1ccccc1Oc1ccccc1)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O CHEMBL3948111 IC50 5.0 nM
CCOC(=O)N1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 CHEMBL3895808 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)C2C[C@H]3CC[C@@H](C2)N3)c1O)Nc1cccc(F)c1Cl CHEMBL3936567 IC50 5.0 nM
CCOC(=O)N1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3C)c2O)CC1 CHEMBL3933806 IC50 5.0 nM
O=C(Nc1ccccc1Oc1ccccc1)Nc1ccc(Cl)c(S(=O)(=O)C2C[C@H]3CC[C@@H](C2)N3)c1O CHEMBL3912422 IC50 5.0 nM
O=C(Nc1ccccc1OC(F)(F)F)Nc1ccc(Cl)c(S(=O)(=O)[C@@H]2CCNC2)c1O CHEMBL3915083 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)[C@@H]2CCNC2)c1O)Nc1cccc2c1OC(F)(F)O2 CHEMBL3950195 IC50 5.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2C[C@H]3CC[C@@H](C2)N3)c1O CHEMBL3952903 IC50 5.0 nM
CCc1ccccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)[C@@H]2CCNC2)c1O CHEMBL3890888 IC50 5.0 nM
O=C(Nc1cccnc1Cl)Nc1ccc(Cl)c(S(=O)(=O)C2C[C@H]3CC[C@@H](C2)N3)c1O CHEMBL3948929 IC50 5.0 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)[C@@H]2CCNC2)c1O)Nc1cccc(F)c1Cl CHEMBL3966527 IC50 5.0 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N(C)C)nc(SCc2cccc(Cl)c2F)n1 CHEMBL3403848 pIC50 5.012 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCOCC2)nc(SCc2cccc(Cl)c2F)n1 CHEMBL3403855 pIC50 5.012 nM
O=C(Nc1ccc(Cl)c(S(=O)(=O)N2CCNCC2)c1O)Nc1cccc(F)c1Cl CHEMBL2178579 IC50 5.1 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(OC)c(F)c1 CHEMBL254173 Ki 5.2 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL404249 IC50 5.7 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccsc1 CHEMBL252898 IC50 5.8 nM
N#Cc1ccc(NC(=O)Nc2ccccc2Br)c(O)c1Br CHEMBL28009 IC50 6.0 nM
CCC(CC)(NS(=O)(=O)c1c(C)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O)N1CCOCC1 CHEMBL221481 IC50 6.0 nM
CC(C)c1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(F)(F)F)c1 CHEMBL442799 Ki 6.0 nM
N#Cc1c(O)nc(SCc2cccc(F)c2F)nc1[C@H]1C[C@@H]1CO CHEMBL3310787 IC50 6.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)C(c3ccccc3)N2)c1O CHEMBL4786074 IC50 6.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(-c2ccccc2)co1 CHEMBL253499 IC50 6.1 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(F)c(C)c1 CHEMBL254570 Ki 6.1 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)C)o1 CHEMBL384889 IC50 6.2 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(Cl)s1 CHEMBL404060 IC50 6.2 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 CHEMBL404059 IC50 6.2 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)on1 CHEMBL253927 IC50 6.3 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C(C)(C)C)[nH]2)c1O CHEMBL3355235 pIC50 6.31 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2C=CCC2)c1O CHEMBL4084412 pIC50 6.31 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C(F)F)o1 CHEMBL253052 IC50 6.8 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NCCNC(=O)OC(C)(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5404638 pKi 6.918 nM
NS(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O CHEMBL359670 IC50 7.0 nM
CN(C)S(=O)(=O)c1c(C(F)(F)F)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O CHEMBL218665 IC50 7.0 nM
Cc1ccc(N/C(=N/C#N)Nc2ccccc2Br)c(O)c1S(=O)(=O)N(C)C CHEMBL376540 IC50 7.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)cnc12 CHEMBL271703 IC50 7.0 nM
C[C@H](F)[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccco1 CHEMBL472749 Ki 7.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(Cl)o3)C(F)(F)F)c(=O)c2=O)c1O CHEMBL491134 Ki 7.0 nM
N#Cc1c(O)nc(SCc2cccc(F)c2F)nc1[C@H]1C[C@@H]1C(N)=O CHEMBL3310788 IC50 7.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)on1 CHEMBL401894 IC50 7.5 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(-c2c(C)noc2C)co1 CHEMBL253706 IC50 7.6 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(F)cc(C(F)(F)F)c1 CHEMBL254980 Ki 7.9 nM
CNc1nc2nc(SCc3cccc(F)c3F)nc(N[C@H](C)CO)c2s1 CHEMBL245180 Log IC50 7.943 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCNCC2)nc(SCc2cccc(Cl)c2F)n1 CHEMBL3403849 pIC50 7.943 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCCC2)nc(SCc2cccc(F)c2F)n1 CHEMBL3403852 pIC50 7.943 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N2CCCCC2)nc(SCc2cccc(F)c2F)n1 CHEMBL3403853 pIC50 7.943 nM
CN(C)C(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/C2CCCC2)c1O CHEMBL214162 IC50 8.0 nM
CCCc1ccccc1Nc1c(Nc2ccc(Cl)c(S(=O)(=O)N3CCN(CC)CC3)c2O)c(=O)c1=O CHEMBL238971 IC50 8.0 nM
COCCNS(=O)(=O)c1c(Cl)ccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O CHEMBL391465 IC50 8.0 nM
CC(C)[C@@H](Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)c1cccc(F)c1 CHEMBL402144 Ki 8.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccoc1 CHEMBL252897 IC50 8.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(C)F)o1 CHEMBL491487 Ki 8.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(-c2ccsc2)co1 CHEMBL253705 IC50 8.2 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1nc(C)no1 CHEMBL252896 IC50 8.2 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ncco1 CHEMBL430116 IC50 8.6 nM
C[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL1162935 pKi 8.71 nM
CCC(CC)(NS(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O)N1C[C@@H](C)O[C@@H](C)C1 CHEMBL218486 IC50 9.0 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2OCc2ccccc2)c1O CHEMBL376621 IC50 9.0 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2F)c1O CHEMBL220797 IC50 9.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(CCCCN2CCOCC2)co1 CHEMBL246107 Ki 9.0 nM
CC[C@@H](Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)c1cc(C(C)C)co1 CHEMBL254942 Ki 9.0 nM
CN(C)C(=O)c1cccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc(Cl)o2)C(C)(C)C)c1O CHEMBL403023 Ki 9.0 nM
CC[C@@H](NC1=NS(=O)(=O)N=C1Nc1cccc(C(=O)N(C)C)c1O)c1ccc2c(c1)OCCN2C CHEMBL252289 Ki 9.0 nM
C=CC(F)(F)[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL491312 Ki 9.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCCC3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL564029 Ki 9.0 nM
COCCS(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)C(c3ccccc3)N2)c1O CHEMBL4763312 IC50 9.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)CCNC(=O)CNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5414239 Kd 9.0 nM
CC[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL380732 IC50 9.5 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(-c2ccncc2)co1 CHEMBL401938 IC50 9.5 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccno1 CHEMBL252698 IC50 9.8 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1nccs1 CHEMBL401893 IC50 9.8 nM
NC(=O)c1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O CHEMBL184185 IC50 10.0 nM
CN(C)C(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/C2CCCCC2)c1O CHEMBL213130 IC50 10.0 nM
CC(C)/N=c1\c(O)c(O)\c1=N/c1cccc(C(=O)N(C)C)c1O CHEMBL375175 IC50 10.0 nM
CN1CCCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Nc4ccccc4Br)c(=O)c3=O)c2O)CC1 CHEMBL556367 IC50 10.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1sccc1C CHEMBL245500 Ki 10.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(F)F)o1 CHEMBL491330 Ki 10.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCOCC3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL563855 Ki 10.0 nM
N#Cc1c(O)nc(SCc2cccc(F)c2F)nc1[C@H]1C[C@@H]1C(=O)O CHEMBL3310786 IC50 10.0 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)C(F)(F)F)nc(SCc2ccccc2)n1 CHEMBL3403840 pIC50 10.0 nM
C[C@@H]1CN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)C[C@H](C)O1 CHEMBL3817880 pIC50 10.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCCC=C2Cl)c1O CHEMBL4068799 pIC50 10.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2C=CCCC2)c1O CHEMBL4090813 pIC50 10.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCC=C2F)c1O CHEMBL4064349 pIC50 10.0 nM
CC1CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)C)c1O CHEMBL4071768 pIC50 10.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCCC2)c1O CHEMBL4093313 pIC50 10.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)[C@@H](C3CCCCC3)N2)c1O CHEMBL4742368 IC50 10.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NCCNC(=O)CNC(=O)OCC3c4ccccc4-c4ccccc43)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5398802 pKi 10.72 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cocn1 CHEMBL252697 IC50 10.9 nM
CN(C)C(=O)c1cccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccco2)C(C)(C)C)c1O CHEMBL253921 Ki 11.0 nM
CC(C)[C@@H](NC1=NS(=O)(=O)N=C1Nc1cccc(C(=O)N(C)C)c1O)c1cccc(F)c1 CHEMBL402076 Ki 11.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL561812 Ki 11.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)cc(C(F)(F)F)c1 CHEMBL404073 Ki 11.8 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(F)c(OC)c1 CHEMBL404917 Ki 11.9 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O CHEMBL183222 IC50 12.0 nM
CCC(CC)(NS(=O)(=O)c1cccc(N/C(=N/C#N)Nc2ccccc2Br)c1O)N1CCOCC1 CHEMBL218744 IC50 12.0 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2C(F)(F)F)c1O CHEMBL222075 IC50 12.0 nM
CN(C)C(=O)c1cccc(Nc2n[s+]([O-])nc2N[C@@H](c2ccco2)C2(C)CC2)c1O CHEMBL252911 Ki 12.0 nM
Cc1ccoc1[C@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)C(C)(F)F CHEMBL491506 Ki 12.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)O)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL562542 Ki 12.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCN(C)CC3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL562286 Ki 12.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2)nc2nc(N)sc12 CHEMBL394799 Log IC50 12.59 nM
C[C@H](CO)Nc1nc(SCc2ccccc2F)nc2nc(N)sc12 CHEMBL232846 Log IC50 12.59 nM
C[C@H](CO)Nc1cc(NS(C)(=O)=O)nc(SCc2cccc(Cl)c2F)n1 CHEMBL3403835 pIC50 12.59 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)c2cn(C)cn2)nc(SCc2cccc(Cl)c2F)n1 CHEMBL3403847 pIC50 12.59 nM
CC1=CCCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)C)c1O CHEMBL4062881 pIC50 12.59 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2-c2ccccc2)c1O CHEMBL425985 IC50 13.0 nM
CN1CCN(S(=O)(=O)c2c(F)ccc(Nc3c(Nc4ccccc4Br)c(=O)c3=O)c2O)CC1 CHEMBL239982 IC50 13.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(N)nc12 CHEMBL257006 IC50 13.0 nM
C[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12 CHEMBL271013 IC50 13.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)[C@H](C)F)o1 CHEMBL514001 Ki 13.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2oncc12 CHEMBL5195797 IC50 13.0 nM
CC(C)[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(F)cc(C(F)(F)F)c1 CHEMBL254981 Ki 13.3 nM
CC(C)[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C(F)(F)F)c(F)c1 CHEMBL254369 Ki 13.9 nM
CC(C)(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL380947 IC50 14.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(C(F)(F)F)cc3)c2)n1 CHEMBL207199 Ki 14.0 nM
CN(C)C(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/C(C)(C)C)c1O CHEMBL211247 IC50 14.0 nM
NC(=O)c1c(Cl)ccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O CHEMBL238743 IC50 14.0 nM
CNS(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(C#N)cc12 CHEMBL257829 IC50 14.0 nM
Cc1coc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)(F)F)c1 CHEMBL523984 Ki 14.0 nM
CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccccc3)C(F)(F)F)c(=O)c2=O)c1O CHEMBL464301 Ki 14.0 nM
COC(=O)c1cc(C(=O)CSc2ccc(C(=O)Nc3ccc(F)cc3)cn2)on1 CHEMBL3658321 IC50 14.0 nM
CCc1ccccc1N/C(=N\C#N)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1O CHEMBL386505 IC50 15.0 nM
Cc1ccccc1Nc1c(Nc2ccc(C)c(S(=O)(=O)N(C)C)c2O)c(=O)c1=O CHEMBL239768 IC50 15.0 nM
N#Cc1ccc(Nc2c(Nc3ccccc3Br)c(=O)c2=O)c(O)c1 CHEMBL239136 IC50 15.0 nM
CN(C)C(=O)c1cccc(Nc2n[s+]([O-])nc2NCc2ccc3c(c2)OCO3)c1O CHEMBL253104 Ki 15.0 nM
CC[C@@H](Nc1c(Nc2ccc(-c3ccccn3)c(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL550130 Ki 15.0 nM
Cc1ccc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3951994 IC50 15.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)CC(F)(F)F)c3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3909470 IC50 15.0 nM
CC(C)(C)OC(=O)NCCCS(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)C(c3ccccc3)N2)c1O CHEMBL4757674 IC50 15.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(Cl)c2Cl)nc2nc(N)sc12 CHEMBL233260 Log IC50 15.85 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2)nc2nc(N)sc12 CHEMBL233059 Log IC50 15.85 nM
C[C@@H](O)[C@@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL389791 Log IC50 15.85 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C3CCC3)[nH]2)c1O CHEMBL3355237 pIC50 15.85 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C3(C)CCC3)[nH]2)c1O CHEMBL3355240 pIC50 15.85 nM
CCC(CC)(NS(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O)N1CCC[C@@H]1C(=O)O CHEMBL387136 IC50 16.0 nM
CCC(C)(C)[C@@H](NC1=NS(=O)(=O)N=C1Nc1cccc(C(=O)N(C)C)c1O)c1ccco1 CHEMBL253922 Ki 16.0 nM
COc1cc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)C)ccc1F CHEMBL254571 Ki 16.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)c(C#N)cc12 CHEMBL403656 IC50 16.0 nM
O=C(CSc1ccc(C(=O)Nc2ccc(F)cc2)cn1)c1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL3658278 IC50 16.0 nM
Cc1ccc(C(Nc2c(Nc3ccc(Cl)c(S(=O)(=O)N(C)C)c3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3913959 IC50 16.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1occc1Br CHEMBL253707 IC50 16.5 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(OC(F)(F)F)cc3)c2)n1 CHEMBL207024 Ki 17.0 nM
Cc1ccccc1N/C(=N\C#N)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1O CHEMBL220860 IC50 17.0 nM
CCC(CC)(NS(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2C)c1O)N1C[C@@H](C)O[C@@H](C)C1 CHEMBL373522 IC50 17.0 nM
CC[C@@H](Nc1c(Nc2ccc(-c3ccccc3)c(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL557877 Ki 17.0 nM
Cc1ccc(C(Nc2c(Nc3ccc(Cl)c(S(=O)(=O)N4CCN(C)CC4)c3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3952996 IC50 17.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(S(=O)(=O)N4CCN(C)CC4)c3O)c(=O)c2=O)[C@H]2CCCS2)o1 CHEMBL4472754 IC50 17.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C(F)(F)F)o1 CHEMBL404250 IC50 17.2 nM
O=c1c(Nc2ccccc2)c(Nc2ccc(Cl)c(S(=O)(=O)N3CCC(N4CCCCC4)CC3)c2O)c1=O CHEMBL537883 IC50 18.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CC[C@H](O)C3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL556656 Ki 18.0 nM
Cc1cc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(C)(=O)=O)c2cc1C#N CHEMBL403084 IC50 19.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C(F)(F)F)c(F)c1 CHEMBL254368 Ki 19.4 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(NC3CC3)sc12 CHEMBL396043 Log IC50 19.95 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C3CCCC3)[nH]2)c1O CHEMBL3355238 pIC50 19.95 nM
CN1CCCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Nc4ccccc4Cl)c(=O)c3=O)c2O)CC1 CHEMBL537441 IC50 20.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CC(O)C3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL562207 Ki 20.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CC[C@H](CO)C3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL556861 Ki 20.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCN(C(=O)c4ccccn4)CC3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL550006 Ki 20.0 nM
COC(=O)CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3CCCS3)c(=O)c2=O)c1O CHEMBL3904195 IC50 20.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1sccc1Cl CHEMBL253504 IC50 21.0 nM
Cc1ccc([C@H](Nc2nsnc2Nc2cccc(C(=O)N(C)C)c2O)C(C)(C)C)o1 CHEMBL455431 IC50 21.0 nM
CC[C@H](CO)Nc1nc(SCc2ccccc2)nc2[nH]c(=O)sc12 CHEMBL2349334 Ki 21.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(SCc2cc(OC(F)(F)F)ccc2B(O)O)nc1 CHEMBL3426944 IC50 21.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(N(Cc2ccc(B(O)O)cn2)Cc2ccco2)nc1 CHEMBL3609016 IC50 21.0 nM
COC(=O)[C@H]1CCCN1C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3CCCS3)c(=O)c2=O)c1O CHEMBL3901913 IC50 21.0 nM
N#Cc1ccc(NC(=O)Nc2ccccc2Br)c(O)c1Cl CHEMBL27446 IC50 22.0 nM
CNC(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/c2ccccc2)c1O CHEMBL377397 IC50 22.0 nM
CCC(CC)(NS(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2ccccc2Br)c1O)N1CCC(N)CC1 CHEMBL386072 IC50 22.0 nM
O=C(Nc1ccc([N+](=O)[O-])cc1O)Nc1ccccc1Br CHEMBL239767 IC50 22.0 nM
O=c1c(O)c(Nc2ccc([N+](=O)[O-])cc2O)/c1=N/c1ccccc1 CHEMBL379438 IC50 22.0 nM
CC[C@@H](Nc1c(Nc2ccccc2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL551747 Ki 22.0 nM
O=C(Nc1ccc(F)cc1)c1cnc(SCc2cc(OC(F)(F)F)ccc2B(O)O)nc1 CHEMBL4297480 IC50 22.0 nM
Cc1ccc(C(Nc2c(Nc3cccnc3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3947915 IC50 23.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NCCNC(=O)OCC3c4ccccc4-c4ccccc43)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5423846 pKi 23.99 nM
CN(C)C(=O)c1cccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc3c(c2)OCCO3)C(C)(C)C)c1O CHEMBL404381 Ki 24.0 nM
Cc1cc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(=O)(=O)N(C)C)c2cc1C#N CHEMBL254568 IC50 24.0 nM
N#Cc1ccc(NC(=O)Nc2ccccc2Br)c(O)c1 CHEMBL27863 IC50 25.0 nM
CCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(OC(F)(F)F)cc3)c2)n1 CHEMBL381597 Ki 25.0 nM
CCc1ccoc1[C@@H](CC)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O CHEMBL245697 Ki 25.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(N)=O)c2O)c(=O)c1=O)c1ccccc1 CHEMBL559031 Ki 25.0 nM
CC(C)c1coc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)COC2)c1 CHEMBL3704565 IC50 25.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)c(F)c(C(C)(C)C)[nH]2)c1O CHEMBL3355247 pIC50 25.12 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)c2ccc(C#N)cc2)nc(SCc2ccccc2)n1 CHEMBL3403843 pIC50 25.12 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCC=C2C(F)(F)F)c1O CHEMBL4091344 pIC50 25.12 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCC3CC32)c1O CHEMBL4064083 pIC50 25.12 nM
O=[N+]([O-])c1cc(O)c2c(c1)S(=O)(=O)N=C(Nc1ccccc1Br)N2 CHEMBL443583 IC50 26.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)CC(F)(F)F)c3O)c(=O)c2=O)C2(C)COC2)o1 CHEMBL3704569 IC50 26.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(Cl)cc3)c2)n1 CHEMBL207497 Ki 27.0 nM
CN1CCN(C(=O)c2cccc(Nc3c(Nc4ccccc4)c(=O)c3=O)c2O)CC1 CHEMBL392473 IC50 27.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N3CCN(C(C)=O)CC3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL562670 Ki 27.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)CCNC(=O)CCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5412421 Kd 27.0 nM
O=C(c1c(Cl)ccc(Nc2c(Nc3ccccc3Br)c(=O)c2=O)c1O)N1CCCC1 CHEMBL399223 IC50 28.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(F)c(F)c1 CHEMBL254172 Ki 28.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NC)c2O)c(=O)c1=O)c1ccccc1 CHEMBL563467 Ki 28.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(SCc2cc(OC(F)(F)F)ccc2O)nc1 CHEMBL3654441 IC50 28.0 nM
CN(C)S(=O)(=O)c1c(Cl)ccc(N/C(=N/C#N)Nc2cccc(Cl)c2F)c1O CHEMBL221039 IC50 29.0 nM
CCC[C@H]1NC(Nc2ccc(Cl)c(S(=O)(=O)C(C)C)c2O)=NC1=O CHEMBL4746698 IC50 29.0 nM
Cc1ccc([C@H](Nc2c(Nc3ccc(Cl)c(S(=O)(=O)N4CCN(C)CC4)c3O)c(=O)c2=O)C2(C)COC2)o1 CHEMBL3704573 IC50 30.0 nM
CCN(CC)CCCCNc1nc2cc(Cl)c(Cl)cc2nc1-c1cc2ccccc2o1 CHEMBL4473520 IC50 30.0 nM
Cc1ccc(C(Nc2c(Nc3ccc(Cl)c(S(=O)(=O)N(C)C)c3O)c(=O)c2=O)C2(C)COC2)o1 CHEMBL3701196 IC50 31.0 nM
C[C@H](CO)Nc1nc(SCc2ccco2)nc2nc(N)sc12 CHEMBL233263 Log IC50 31.62 nM
C[C@H](CO)Nc1nc(SCc2ccccc2Cl)nc2nc(N)sc12 CHEMBL233259 Log IC50 31.62 nM
CC(C)Nc1nc2nc(SCc3cccc(F)c3F)nc(N[C@H](C)CO)c2s1 CHEMBL437013 Log IC50 31.62 nM
Nc1nc2nc(SCc3cccc(F)c3F)nc(NC(CO)CO)c2s1 CHEMBL245190 Log IC50 31.62 nM
CC1CCCC1c1cc(=O)nc(Nc2ccc(Cl)c(S(=O)(=O)C(C)C)c2O)[nH]1 CHEMBL3355239 pIC50 31.62 nM
C[C@H](CO)Nc1cc(NS(C)(=O)=O)nc(SCc2cccc(F)c2F)n1 CHEMBL3403834 pIC50 31.62 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)c2ccc(Cl)cc2)nc(SCc2ccccc2)n1 CHEMBL3403842 pIC50 31.62 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)c2cn(C)cn2)nc(SCc2cccc(F)c2F)n1 CHEMBL3403846 pIC50 31.62 nM
CC1=CCC[C@H]1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(CCF)CCOCC2)c1O CHEMBL4070629 pIC50 31.62 nM
O=C(O)c1cccc(S(=O)(=O)c2ccc(C(=O)Nc3ccc(F)cc3)c[n+]2[O-])c1 CHEMBL57680 IC50 32.0 nM
COC(=O)CSc1ccc(C(=O)Nc2ccc(F)cc2)cn1 CHEMBL431511 IC50 32.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(O)cc3)c2)n1 CHEMBL383633 Ki 32.0 nM
N#Cc1cccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O CHEMBL240817 IC50 32.0 nM
O=c1c(Nc2ccc(Cl)cc2O)c(Nc2ccccc2Br)c1=O CHEMBL441144 IC50 32.0 nM
CS(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(C#N)cc12 CHEMBL440405 IC50 32.0 nM
Cc1coc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)COC2)c1 CHEMBL3704564 IC50 32.0 nM
O=C(Nc1ccc(F)cn1)c1ccc(OCc2ccccc2B(O)O)nc1 CHEMBL3658341 IC50 32.0 nM
NC(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/c2ccccc2)c1O CHEMBL214286 IC50 34.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NC3CC3)c2O)c(=O)c1=O)c1ccccc1 CHEMBL564068 Ki 34.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc2c(c1O)S(=O)(=O)CC=C2 CHEMBL5088269 IC50 34.0 nM
CCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3cccc(OC(F)(F)F)c3)c2)n1 CHEMBL207856 Ki 35.0 nM
Cc1ccc([C@H](Nc2nsnc2Nc2cccc(C(=O)N(C)C)c2O)C(C)C)o1 CHEMBL510437 IC50 36.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(F)cc3)c2)n1 CHEMBL207498 Ki 37.0 nM
O=c1c(Nc2ccc([N+](=O)[O-])cc2O)c(Nc2ccccc2Br)c1=O CHEMBL239348 IC50 37.0 nM
COC(=O)[C@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O CHEMBL3701188 IC50 37.0 nM
O=C(Nc1ccc(F)cc1O)c1ccc(SCc2ccccc2B(O)O)nc1 CHEMBL3658338 IC50 37.0 nM
COC(=O)[C@@H]1CCCN1C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3CCCS3)c(=O)c2=O)c1O CHEMBL3915145 IC50 37.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(SCc2ccccc2B(O)O)nc1 CHEMBL3342269 IC50 38.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(F)c(C(F)(F)F)c1 CHEMBL254572 Ki 38.5 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCCC23CC3)c1O CHEMBL4085657 pIC50 39.81 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(C)cc3)c2)n1 CHEMBL381705 Ki 40.0 nM
N#Cc1c(O)nc(SCc2cccc(F)c2F)nc1C1CC1 CHEMBL3310783 IC50 40.0 nM
CN(C)C(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/Cc2ccco2)c1O CHEMBL211609 IC50 41.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(OC)cc3)c2)n1 CHEMBL207742 Ki 42.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(C#N)cc3)c2)n1 CHEMBL207376 Ki 43.0 nM
CCCCC1NC(Nc2ccc(Cl)c(S(=O)(=O)C(C)C)c2O)=NC1=O CHEMBL4747035 IC50 43.0 nM
O=C(Nc1ccc2c(c1O)S(=O)(=O)CCC2)Nc1cccc(F)c1Cl CHEMBL5081049 IC50 43.0 nM
CCOCCCNC(=O)[C@H](CC(C)C)Nc1cc(C)nc(-n2cnc(-c3ccc(OC(F)(F)F)cc3)c2)n1 CHEMBL380644 Ki 44.0 nM
CN1CCCN(C(=O)c2cccc(Nc3c(Nc4ccccc4)c(=O)c3=O)c2O)CC1 CHEMBL240458 IC50 44.0 nM
CN(CCC#N)C(=O)c1cccc(Nc2nsnc2N[C@@H](c2ccco2)C(C)(C)C)c1O CHEMBL462331 Ki 44.0 nM
Cc1ccc(C(Nc2c(NC3=CC=CN(C)C3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3986396 IC50 44.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]nnc12 CHEMBL5173775 IC50 44.0 nM
C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)c(=O)[nH]c12 CHEMBL403877 IC50 45.0 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NCCNC(=O)CCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5413545 Kd 45.0 nM
O=C(c1cccc(Nc2c(NC3C[C@@H]4CC[C@H]3C4)c(=O)c2=O)c1O)N1CCCC1 CHEMBL4466314 IC50 48.0 nM
Sc1nc(-c2ccccc2Cl)nn1Cc1cccc(Cl)c1 CHEMBL309253 IC50 48.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(-c2ccccc2Cl)o1 CHEMBL402952 IC50 49.0 nM
O=C(Nc1ccccc1Br)Nc1ccc2c(c1O)S(=O)(=O)CC=C2 CHEMBL5076154 IC50 49.0 nM
CC(C)(CO)Nc1nc(SCc2cccc(Oc3ccccc3)c2)nc2nc(N)sc12 CHEMBL204552 IC50 50.0 nM
CCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccccc3OC(F)(F)F)c2)n1 CHEMBL379549 Ki 50.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccncc1 CHEMBL253506 IC50 50.0 nM
CC[C@@H](Nc1c(Nc2cc(Cl)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 CHEMBL550880 Ki 50.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)c(F)c(C3CCC3)[nH]2)c1O CHEMBL3355248 pIC50 50.12 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)Cc2ccccc2)nc(SCc2ccccc2)n1 CHEMBL3403839 pIC50 50.12 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCCCC2)c1O CHEMBL4076769 pIC50 50.12 nM
CC[C@@H](Nc1c(Nc2cccc(C(=O)NCCNC(=O)CCCCCNC(=O)COc3ccc(/C=C/C4=[N+]5C(=Cc6ccc(-c7cccs7)n6[B-]5(F)F)C=C4)cc3)c2O)c(=O)c1=O)c1ccc(C)o1 CHEMBL5420355 pKd 50.12 nM
O=c1c(Nc2ccccc2O)c(Nc2ccccc2Br)c1=O CHEMBL391372 IC50 51.0 nM
O=c1c(Nc2ccccc2)c(Nc2cc(Cl)c([N+](=O)[O-])cc2O)c1=O CHEMBL238511 IC50 52.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(SCc2cc(F)ccc2B(O)O)nc1 CHEMBL3426949 IC50 52.0 nM
COC(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/c2ccccc2)c1O CHEMBL380052 IC50 53.0 nM
Cc1ccc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)CCCO2)o1 CHEMBL3979652 IC50 53.0 nM
O=S1(=O)N=C(Nc2ccccc2Oc2ccccc2)Nc2c(O)cc(Cl)cc21 CHEMBL233346 IC50 54.0 nM
O=[N+]([O-])c1cc(O)c2c(c1)S(=O)(=O)N=C(Nc1ccccc1Oc1ccccc1)N2 CHEMBL399203 IC50 54.0 nM
O=c1c(Nc2ccccc2)c(Nc2cc(Cl)ccc2O)c1=O CHEMBL238724 IC50 54.0 nM
CCN(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccc1 CHEMBL570042 IC50 54.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)C(c3ccccc3Cl)N2)c1O CHEMBL4752486 IC50 54.0 nM
O=c1c(O)c(Nc2cc([N+](=O)[O-])ccc2O)/c1=N/c1ccccc1 CHEMBL209858 IC50 56.0 nM
N#Cc1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O CHEMBL26830 IC50 57.0 nM
CCOCCCNC(=O)[C@H](CC(C)C)Nc1cc(CC)nc(-n2cnc(-c3ccc(OC(F)(F)F)cc3)c2)n1 CHEMBL206987 Ki 57.0 nM
COc1cc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(=O)(=O)N(C)C)c2cc1C#N CHEMBL254567 IC50 57.0 nM
C[C@H](Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)C(C)(C)C CHEMBL403936 Ki 58.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(-c2cccc(Cl)c2)o1 CHEMBL254516 IC50 58.0 nM
CC1(C)C2CC3OB(c4ccccc4CSc4ccc(C(=O)Nc5ccc(F)cc5)cn4)OC3(C)C1C2 CHEMBL3654444 IC50 59.0 nM
CCCCCCCCSc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2ccnc2)n1 CHEMBL207725 Ki 60.0 nM
Cc1nc(CSc2nc(N[C@H](C)CO)c3sc(=O)[nH]c3n2)cs1 CHEMBL402728 IC50 60.0 nM
COC(=O)[C@@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O CHEMBL3640000 IC50 60.0 nM
CC[C@@H](Nc1c(Nc2cc(Br)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 CHEMBL562950 Ki 61.0 nM
O=C(Nc1ccccc1Br)Nc1ccc(Cl)c(Cl)c1O CHEMBL185259 IC50 63.0 nM
C[C@@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL414894 Log IC50 63.1 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)N(C)C)nc(SCc2ccccc2)n1 CHEMBL3403845 pIC50 63.1 nM
CCC1CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C(C)C)c1O CHEMBL4102423 pIC50 63.1 nM
O=S1(=O)N=C(Nc2cccc(F)c2Cl)Nc2c(O)cc(Cl)cc21 CHEMBL393253 IC50 64.0 nM
O=S1(=O)N=C(Nc2ccccc2Br)Nc2c(O)cc(Cl)cc21 CHEMBL393047 IC50 64.0 nM
CCS(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(C#N)cc12 CHEMBL255483 IC50 64.0 nM
CC(C)C[C@H](CO)Nc1nc(SCc2ccccn2)nc2nc(N)sc12 CHEMBL2349307 Ki 64.0 nM
CCNC(=O)c1cccc(/N=c2\c(O)c(O)\c2=N/c2ccccc2)c1O CHEMBL213943 IC50 65.0 nM
N#Cc1ccc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(N)(=O)=O)c2c1 CHEMBL257830 IC50 66.0 nM
O=C(Nc1ccccc1Cl)Nc1ccc2c(c1O)S(=O)(=O)CC=C2 CHEMBL5078788 IC50 66.0 nM
CCCC1NC(Nc2ccc(Cl)c(S(=O)(=O)C(C)C)c2O)=NC1=O CHEMBL4793352 IC50 68.0 nM
Cc1ccc(C(Nc2c(Nc3ccc(Cl)c(C(=O)N(C)C)c3O)c(=O)c2=O)C2CCCS2)o1 CHEMBL3956601 IC50 69.0 nM
O=S1(=O)N=C(Nc2ccccc2Br)Nc2c(O)cc(Br)cc21 CHEMBL396411 IC50 70.0 nM
N#Cc1ccc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(=O)(=O)C(F)(F)F)c2c1 CHEMBL257178 IC50 70.0 nM
Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)COC2)o1 CHEMBL3704570 IC50 72.0 nM
CCN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O CHEMBL3704571 IC50 72.0 nM
CC1(C)OB(c2ccc(OC(F)(F)F)cc2CSc2ccc(C(=O)Nc3ccc(F)cc3)cn2)OC1(C)C CHEMBL3654446 IC50 72.0 nM
N#Cc1ccc(O)c(Nc2c(O)c(=O)/c2=N\c2ccccc2)c1 CHEMBL378503 IC50 74.0 nM
CCN(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccn1 CHEMBL585928 IC50 75.0 nM
CC[C@@H](Nc1c(Nc2cc(C)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 CHEMBL550945 Ki 76.0 nM
O=C(c1ccc(SCc2ccccc2B(O)O)nc1)N(Cc1ccccn1)c1ccc(F)cc1 CHEMBL3342320 IC50 78.0 nM
O=c1c(Nc2ccccc2Br)c(Nc2ccc3c(c2O)S(=O)(=O)CC=C3)c1=O CHEMBL5070965 IC50 78.0 nM
CC(C)c1coc([C@H](Nc2nsnc2Nc2cccc(C(=O)N(C)CCC#N)c2O)C(C)(C)C)c1 CHEMBL462156 Ki 79.0 nM
CC(C)C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL2349333 Ki 79.0 nM
CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)nc2[nH]c(=O)sc12 CHEMBL2349321 Ki 79.0 nM
COc1ccc(B(O)O)c(CSc2ccc(C(=O)Nc3ccc(F)cc3)cn2)c1 CHEMBL3426945 IC50 79.0 nM
CC(CO)(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 CHEMBL389792 Log IC50 79.43 nM
C[C@H](CO)Nc1cc(NS(C)(=O)=O)nc(SCc2ccccc2)n1 CHEMBL3403830 pIC50 79.43 nM
C[C@H](CO)Nc1cc(NS(=O)(=O)c2ccccc2)nc(SCc2ccccc2)n1 CHEMBL3403841 pIC50 79.43 nM
CC(C)(CCO)S(=O)(=O)c1c(Cl)ccc(NC(=O)N[C@H]2CCC=C2Cl)c1O CHEMBL4059587 pIC50 79.43 nM
COC(=O)CNCC(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3CCCS3)c(=O)c2=O)c1O CHEMBL3935902 IC50 80.0 nM
O=[N+]([O-])c1cc(O)c2c(c1)S(=O)(=O)N=C(Nc1ccccc1Cl)N2 CHEMBL231924 IC50 81.0 nM
CN(Cc1ccc(B(O)O)cn1)c1ccc(C(=O)Nc2ccc(F)cc2)cn1 CHEMBL3609006 IC50 81.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(SCC(=O)c2cc(C(=O)O)no2)nc1 CHEMBL3639571 IC50 81.0 nM
Cc1ccc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)[C@@H]2CCCO2)o1 CHEMBL3934321 IC50 83.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(C(C)(C)C)c2)n1 CHEMBL382377 Ki 85.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(-c2cccc(C(F)(F)F)c2)o1 CHEMBL251890 IC50 87.0 nM
O=C(Nc1ccc(F)cc1)c1ccc(S(=O)(=O)c2ccccc2)[n+]([O-])c1 CHEMBL301424 IC50 90.0 nM
CCCCc1cc(N[C@@H](CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(C)c2)n1 CHEMBL207276 Ki 90.0 nM
CS(=O)(=O)NC(=O)NCCc1c(-c2ccc(F)cc2)[nH]c2ccc(Br)cc12 CHEMBL404661 IC50 90.0 nM
Sc1nc(-c2ccc(Cl)cc2Cl)nn1Cc1cccc(Cl)c1 CHEMBL82566 IC50 92.0 nM
O=S1(=O)N=C(Nc2ccccc2Cl)Nc2c(O)cc(Cl)cc21 CHEMBL234186 IC50 92.0 nM
CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(CN(C)C)o1 CHEMBL404251 IC50 94.0 nM
Cc1c(F)cccc1NC(=O)Nc1ccc2c(c1O)S(=O)(=O)CCC2 CHEMBL5093947 IC50 95.0 nM
Cc1ccc([C@H](Nc2c(Nc3csc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)COC2)o1 CHEMBL3640034 IC50 96.0 nM
CC(C)S(=O)(=O)c1c(Cl)ccc(NC2=NC(=O)[C@@H](Cc3ccccc3)N2)c1O CHEMBL4741864 IC50 98.0 nM