CC(C)(C(=O)c1cccnc1)c1cccnc1 CHEMBL934 IC50 0.0 nM
CCCCCCCN1C(=O)CC(c2ccc(N)cc2)C1=O CHEMBL5425696 pIC50 1.259e-09 nM
N#Cc1ccc(CC(c2cccc3[nH]ccc23)n2ccnn2)cc1 CHEMBL5411570 pIC50 0.0008147 nM
N#Cc1ccc(C2CCCc3cncn32)cc1 CHEMBL9298 IC50 0.004 nM
CCC#CCOc1cc(Cn2ccnc2)c2c(=O)c3ccccc3oc2c1 CHEMBL4639677 IC50 0.01 nM
CCC#CCOc1ccc2c(=O)c3ccc(Cn4ccnc4)cc3oc2c1 CHEMBL4632445 IC50 0.01 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(Cl)c2)n2cnnc2)cc1-c1ccccc1 CHEMBL1672978 IC50 0.015 nM
COc1ccc(-c2cc(N(Cc3ccc(OS(N)(=O)=O)cc3)n3cnnc3)ccc2C#N)cc1 CHEMBL1672980 IC50 0.015 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(Br)c2)n2cnnc2)cc1-c1ccccc1 CHEMBL1672979 IC50 0.018 nM
N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1 CHEMBL1444 Ki 0.02 nM
N#Cc1ccc(C(CCc2ccc(O)c(Br)c2)n2cncn2)cc1 CHEMBL5438093 pIC50 0.02 nM
N#Cc1ccc(N(Cc2ccc(O)cc2F)n2ccnc2)cc1 CHEMBL5425028 pIC50 0.02799 nM
N#Cc1ccc(C2CCCc3cncn32)cc1 CHEMBL468419 IC50 0.03 nM
C[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL310735 IC50 0.037 nM
CC12CCCC=C1CCC1C2CCC2(C)C1CC[C@@H]2O CHEMBL73279 Ki app 0.045 nM
C[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL305205 IC50 0.049 nM
CC12CCC3C(C[C@@H](O)C4=CCCCC43C)C1CCC2=O CHEMBL73993 IC50 0.05 nM
N#Cc1ccc(N(Cc2ccc(Br)cc2)n2cnnc2)cc1-c1ccc(OS(N)(=O)=O)cc1 CHEMBL1672975 IC50 0.05 nM
C[C@]12CCCC=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL1629804 IC50 0.06 nM
c1cncc(-c2csc(-c3ccncc3)n2)c1 CHEMBL1957214 Ki 0.06 nM
Cc1c(Cn2ccnc2)ccc2c(F)cc(F)cc12 CHEMBL5396048 pIC50 0.08872 nM
CC#CCOc1ccc2cc(C(c3ccc(C#N)cc3)n3cncn3)oc2c1 CHEMBL5203413 IC50 0.09 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(-c2ccc(O)c(Cl)c2)c1 CHEMBL597416 IC50 0.1 nM
N#Cc1ccc(N(Cc2ccccc2)n2cnnc2)cc1-c1ccc(OS(N)(=O)=O)cc1 CHEMBL1672974 IC50 0.1 nM
N#Cc1ccc(C(CCc2ccc(OS(N)(=O)=O)c(Br)c2)n2cncn2)cc1 CHEMBL3623231 IC50 0.1 nM
N#Cc1ccc(N(Cc2ccc3c(Br)c(O)ccc3c2)n2cnnc2)cc1 CHEMBL5408436 pIC50 0.1 nM
CC[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL70436 IC50 0.11 nM
COc1ccc2cc(C(c3ccc(C#N)cc3)n3cncn3)oc2c1 CHEMBL197650 IC50 0.11 nM
CO[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL307581 IC50 0.12 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccc(OS(N)(=O)=O)c(Cl)c1 CHEMBL592131 IC50 0.12 nM
N#Cc1ccc(N(Cc2ccc(Br)cc2)n2cnnc2)cc1 CHEMBL108425 IC50 0.12 nM
O=[N+]([O-])c1ccc(N(Cc2ccc(Br)cc2)n2cnnc2)cc1 CHEMBL4520995 IC50 0.12 nM
CO[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL308537 IC50 0.13 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(C(C)(C)C#N)c1 CHEMBL1399 Ki 0.13 nM
C[C@@H]1CC2C(CCC3(C)C(O)CCC23)C2(C)CCCC=C12 CHEMBL73367 Ki app 0.14 nM
N#Cc1ccc(N(CCc2c(F)cc(O)cc2F)C2C=NN=C2)cc1 CHEMBL5401648 pIC50 0.14 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccc(O)c(Cl)c1 CHEMBL597808 IC50 0.15 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(F)c2)n2cnnc2)cc1-c1ccccc1 CHEMBL1672977 IC50 0.15 nM
COc1ccc2cc(C(c3ccc(F)cc3)n3cncn3)oc2c1 CHEMBL198291 IC50 0.15 nM
CC(=O)O[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL72228 IC50 0.16 nM
C[C@]12CCC(=O)C(O)=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL132530 Ki 0.16 nM
N#Cc1ccc(C(CCc2ccc(O)cc2)n2cncn2)cc1 CHEMBL5436996 pIC50 0.16 nM
CC[C@H]1CC2C(CCC3(C)C(O)CCC23)C2(C)CCCC=C12 CHEMBL74339 Ki app 0.18 nM
N#Cc1ccc(N(Cc2ccc(Cl)c(O)c2)n2cnnc2)cc1 CHEMBL226946 IC50 0.18 nM
CC12CCC3C(C[C@H](O)C4=CCCCC43C)C1CCC2=O CHEMBL307643 IC50 0.19 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccccc1 CHEMBL592852 IC50 0.2 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccc(O)cc1 CHEMBL597606 IC50 0.2 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)cc2F)n2ccnc2)cc1 CHEMBL3623232 IC50 0.2 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)cc2F)n2cnnc2)cc1 CHEMBL4465348 IC50 0.2 nM
N#Cc1ccc(C(Cc2ccc(O)c(Br)c2)n2cncn2)cc1 CHEMBL5406734 pIC50 0.2099 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1-c1ccccc1 CHEMBL1672976 IC50 0.21 nM
N#Cc1ccc(C(CCc2ccc(OS(N)(=O)=O)cc2)n2cncn2)cc1 CHEMBL5416513 pIC50 0.2198 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccc(Cl)c(O)c1 CHEMBL599864 IC50 0.22 nM
N#Cc1ccc(Cn2cncn2)cc1-c1cccc(Cl)c1 CHEMBL589974 IC50 0.22 nM
CCC[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL304305 IC50 0.23 nM
N#Cc1ccc(N(Cc2ccc3c(Br)c(OS(N)(=O)=O)ccc3c2)n2cnnc2)cc1 CHEMBL3622064 IC50 0.25 nM
N#Cc1ccc(N(CC2CCc3cc(O)ccc3C2)n2cnnc2)cc1 CHEMBL5404073 pIC50 0.25 nM
CC(=O)O[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL304770 IC50 0.26 nM
N#Cc1ccc(N(CCSc2ccc(O)c(Cl)c2)n2cnnc2)cc1 CHEMBL3622055 IC50 0.26 nM
N#Cc1ccc(N(CCc2ccc(O)c(Cl)c2)n2cnnc2)cc1 CHEMBL5412416 pIC50 0.2799 nM
N#Cc1ccc(N(CCSc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL3622054 pIC50 0.2799 nM
N#Cc1ccc(N(CCCSc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5440424 pIC50 0.2799 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(-c2ccc(OS(N)(=O)=O)c(Cl)c2)c1 CHEMBL604716 IC50 0.3 nM
N#Cc1ccc(N(CCSc2cccc(O)c2)n2cnnc2)cc1 CHEMBL5401315 pIC50 0.3097 nM
CC[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL307690 IC50 0.32 nM
N#Cc1ccc(N(Cc2ccc(O)c(I)c2)n2cnnc2)cc1 CHEMBL226790 IC50 0.33 nM
CC[C@@H]1CC2C(CCC3(C)C(O)CCC23)C2(C)CCCC=C12 CHEMBL306022 Ki app 0.34 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccc(Cl)c(OS(N)(=O)=O)c1 CHEMBL599239 IC50 0.35 nM
N#Cc1ccc(N(CCc2ccc(O)c(Br)c2)n2cnnc2)cc1 CHEMBL5417335 pIC50 0.3597 nM
N#Cc1ccc(N(CCCc2ccc(O)c(Br)c2)n2cnnc2)cc1 CHEMBL5402457 pIC50 0.3597 nM
N#Cc1ccc(N(CCSCc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5421435 pIC50 0.3698 nM
C[C@H]1CC2C(CCC3(C)C(O)CCC23)C2(C)CCCC=C12 CHEMBL70959 Ki app 0.38 nM
N#Cc1ccc(N(CSc2cccc(O)c2)n2cnnc2)cc1 CHEMBL5410657 pIC50 0.3802 nM
N#Cc1ccc(N(CCCc2ccc(O)c(Cl)c2)n2cnnc2)cc1 CHEMBL5407526 pIC50 0.3899 nM
Oc1ccc2cc(C(c3ccc(F)cc3)n3cncn3)oc2c1 CHEMBL5175340 IC50 0.39 nM
N#Cc1ccc(N(Cc2ccc(C(F)(F)F)c(O)c2)n2cnnc2)cc1 CHEMBL226999 IC50 0.4 nM
COc1ccc2cc(C(O)(c3ccc(Br)cc3)c3cccnc3)oc2c1 CHEMBL5271052 IC50 0.4 nM
N#Cc1ccc(N(CCc2ccc(O)c(F)c2)n2cnnc2)cc1 CHEMBL5396464 pIC50 0.4102 nM
N#Cc1ccc(N(CCCCCCCCCCSc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5440379 pIC50 0.4198 nM
N#Cc1ccc(N(CCSc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL3622056 pIC50 0.4198 nM
Oc1ccccc1-c1csc(-c2ncccn2)n1 CHEMBL4227385 IC50 0.42 nM
CCC[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL70317 IC50 0.44 nM
N#Cc1ccc(N(CCSc2ccc(OS(N)(=O)=O)c(Cl)c2)n2cnnc2)cc1 CHEMBL3622057 pIC50 0.4498 nM
CCOc1ccc2cc(C(c3ccc(Cl)cc3)n3cncn3)oc2c1 CHEMBL5184004 IC50 0.46 nM
COc1ccc2cc(C(O)(c3ccc(Cl)cc3)c3cccnc3)oc2c1 CHEMBL202612 IC50 0.46 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1-c1ccc(F)cc1 CHEMBL1672981 IC50 0.47 nM
COc1ccc2cc(C(c3ccc(Cl)cc3)n3cncn3)oc2c1 CHEMBL382902 IC50 0.47 nM
N#Cc1ccc(N(Cc2ccc(Br)c(O)c2)n2cnnc2)cc1 CHEMBL226947 IC50 0.5 nM
CN(C)S(=O)(=O)Oc1ccc(-c2cc(Cn3cncn3)ccc2C#N)cc1 CHEMBL596779 IC50 0.5 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(-c2ccccc2)c1 CHEMBL598224 IC50 0.5 nM
COc1cc(CN(c2ccc(C#N)cc2)n2cnnc2)cc(Cl)c1O CHEMBL388507 IC50 0.51 nM
N#Cc1ccc(N(CCCSc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL3622058 IC50 0.51 nM
CCC#CCOc1ccc2cc(C(c3ccc(F)cc3)n3cncn3)oc2c1 CHEMBL5177269 IC50 0.51 nM
CC#CCOc1ccc2cc(C(c3ccc(Cl)cc3)n3cncn3)oc2c1 CHEMBL5174567 IC50 0.53 nM
N#Cc1ccc(C(c2cc3ccc(O)cc3o2)n2cncn2)cc1 CHEMBL202226 IC50 0.56 nM
N#Cc1ccc(N(CCCCCSc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5439970 pIC50 0.5998 nM
N#Cc1ccc(N(Cc2c(Cl)cc(OS(N)(=O)=O)cc2Cl)n2cnnc2)cc1 CHEMBL5402413 pIC50 0.5998 nM
N#Cc1ccc(N(Cc2ccc(F)c(O)c2)n2cnnc2)cc1 CHEMBL390079 IC50 0.6 nM
N#Cc1ccc([C@H](c2ccc(O)c(Br)c2)n2cncn2)cc1 CHEMBL453736 IC50 0.6 nM
COc1cc(-c2nc(-c3cccnc3)cs2)ccn1 CHEMBL1957217 Ki 0.65 nM
N#Cc1ccc(N(CCSCc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5402619 pIC50 0.6501 nM
C=C(c1ccc(C#N)cc1)n1ccnc1 CHEMBL31760 pIC50 0.6998 nM
CCC#CCOc1ccc2cc(C(c3ccc(C#N)cc3)n3cncn3)oc2c1 CHEMBL5179009 IC50 0.72 nM
N#Cc1ccc(N(CCCCCSc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL3622059 pIC50 0.7295 nM
COc1ccc2cc(C(O)(c3ccc(F)cc3)c3cccnc3)oc2c1 CHEMBL372999 IC50 0.74 nM
N#Cc1ccc(-c2cc(N(Cc3ccc(OS(N)(=O)=O)cc3)n3cnnc3)ccc2C#N)cc1 CHEMBL1672982 IC50 0.75 nM
N#Cc1ccc(N(Cc2ccc(F)c(OS(N)(=O)=O)c2)n2cnnc2)cc1 CHEMBL226892 IC50 0.77 nM
CCC#CCOc1cc(Cn2ccnc2)c2oc3ccccc3c(=O)c2c1 CHEMBL4634777 IC50 0.77 nM
Oc1ccc2cc(C(c3ccc(Cl)cc3)n3cncn3)oc2c1 CHEMBL446706 IC50 0.79 nM
N#Cc1ccc(Cn2cncn2)c(-c2ccc(O)c(Cl)c2)c1 CHEMBL598223 IC50 0.8 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(Br)c2)n2cnnc2)cc1 CHEMBL108483 IC50 0.82 nM
CC#CCOc1ccc2cc(C(O)(c3ccc(Br)cc3)c3cccnc3)oc2c1 CHEMBL5283822 IC50 0.83 nM
N#Cc1ccc(C(Cc2ccc(OS(N)(=O)=O)c(Br)c2)n2cncn2)cc1 CHEMBL3818343 pIC50 0.871 nM
N#Cc1ccc(N(Cc2ccc(O)c(C(F)(F)F)c2)n2cnnc2)cc1 CHEMBL226842 IC50 0.88 nM
N#Cc1ccc(N(CCCc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5431850 pIC50 0.8892 nM
O=S(=O)(Oc1ccc(C(F)(F)F)cc1)C1CC2OC1C(c1ccc(-n3ccnc3)cc1)=C2c1ccc(O)cc1 CHEMBL5433442 IC50 0.9 nM
N#Cc1ccc(N(Cc2ccc(Cl)c(OS(N)(=O)=O)c2)n2cnnc2)cc1 CHEMBL390077 IC50 0.92 nM
CCC#CCOc1ccc2cc(C(O)(c3ccc(Cl)cc3)c3cccnc3)oc2c1 CHEMBL5280326 IC50 0.92 nM
C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL1200374 Ki 0.95 nM
C[C@]12CCC3C(CCC4=CC(=O)CC[C@]43C3CS3)C1CCC2=O CHEMBL281433 Ki 1.0 nM
CSC[C@]12CCC(=O)C=C1CCC1C2CC[C@]2(C)C(=O)CCC12 CHEMBL101540 Ki 1.0 nM
C[C@]12CCC3C(CCC4=CC(=O)CC[C@@]43C(F)F)C1CCC2=O CHEMBL98998 Ki 1.0 nM
COc1ccc(C2=C(c3ccc(OC)c(OC)c3)C(=O)OC2)cc1OC CHEMBL1098382 IC50 1.0 nM
O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12 CHEMBL117 IC50 1.0 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43[C@@H]3CO3)[C@@H]1CCC2=O CHEMBL3753593 Ki 1.0 nM
CSC[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3753548 Ki 1.0 nM
N#Cc1ccc(N(CCCc2ccc(O)c(F)c2)n2cnnc2)cc1 CHEMBL5399449 pIC50 1.0 nM
N#Cc1ccc(N(CCCCSc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5417041 pIC50 1.0 nM
C#CCOc1ccc2cc(C(c3ccc(Cl)cc3)n3cncn3)oc2c1 CHEMBL5197552 IC50 1.03 nM
CC#CCOc1ccc2cc(C(O)(c3ccc(Cl)cc3)c3cccnc3)oc2c1 CHEMBL5272700 IC50 1.05 nM
N#Cc1ccc(N(CCc2ccc(OS(N)(=O)=O)c(Br)c2)n2cnnc2)cc1 CHEMBL5397670 pIC50 1.099 nM
N#Cc1ccc(N(Cc2ccc(O)cc2Br)n2cnnc2)cc1 CHEMBL5412669 pIC50 1.099 nM
N#Cc1ccc(N(Cc2ccc(O)c(Br)c2)n2cnnc2)cc1 CHEMBL388506 IC50 1.1 nM
COc1ccc(CN(c2ccc(C#N)cc2)n2cnnc2)cc1O CHEMBL388093 IC50 1.2 nM
C[C@]12CCC(=O)C=C1C[C@@H](Sc1ccc(N=[N+]=[N-])cc1)C1C2CC[C@]2(C)C(=O)CCC12 CHEMBL98537 Ki 1.3 nM
O=S(=O)(Oc1ccc(Br)cc1)C1CC2OC1C(c1ccc(-n3ccnc3)cc1)=C2c1ccc(O)cc1 CHEMBL5412790 IC50 1.3 nM
N#Cc1ccc(N(CCc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5402090 pIC50 1.3 nM
N#Cc1ccc(N(Cc2c(F)cc(OS(N)(=O)=O)cc2F)n2cnnc2)cc1 CHEMBL5395326 pIC50 1.3 nM
N#Cc1ccc(N(Cc2c(F)cc(O)cc2F)n2cnnc2)cc1 CHEMBL5404820 pIC50 1.3 nM
Cn1nnc2ccc([C@@H](c3ccc(Cl)cc3)n3cncn3)cc21 CHEMBL519436 IC50 1.38 nM
Cn1nnc2ccc([C@H](c3ccc(Cl)cc3)n3cncn3)cc21 CHEMBL224060 IC50 1.38 nM
CC[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL25059 Ki 1.4 nM
C[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3754471 Ki 1.4 nM
CCCC[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3752668 Ki 1.4 nM
C[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3754220 Ki 1.4 nM
CC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3752661 Ki 1.4 nM
CCCC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3752102 Ki 1.4 nM
Cn1nnc2ccc(C(c3ccc(Cl)cc3)n3cncn3)cc21 CHEMBL100749 IC50 1.4 nM
NS(=O)(=O)Oc1ccc(CC(c2ccc(Cl)cc2)n2cncn2)cc1Br CHEMBL5413153 pIC50 1.4 nM
CCCCN1C(=O)C2CC2(c2ccc(N)cc2)C1=O CHEMBL174909 Ki app 1.5 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(I)c2)n2cnnc2)cc1 CHEMBL390496 IC50 1.5 nM
N#Cc1ccc(N(CCCc2ccc(OS(N)(=O)=O)c(Br)c2)n2cnnc2)cc1 CHEMBL5423824 pIC50 1.5 nM
N#Cc1ccc(N(CCCOc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5400488 pIC50 1.5 nM
Cn1cc(CCN(c2ccc(C#N)cc2)n2cnnc2)c2cc(O)ccc21 CHEMBL5424630 pIC50 1.5 nM
N#Cc1ccc(N(CCc2coc3cc(O)ccc23)n2cnnc2)cc1 CHEMBL5412425 pIC50 1.5 nM
N#Cc1ccc(N(Cc2ccc(O)c(C(F)F)c2)n2ccnc2)cc1 CHEMBL5413848 pIC50 1.5 nM
OC(c1cn(Cc2ccccc2F)c2ccccc12)n1ccnc1 CHEMBL5434047 pIC50 1.581 nM
N#Cc1ccc(N(CCCc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5413770 pIC50 1.6 nM
N#Cc1ccc(N(CCc2ccc(OS(N)(=O)=O)c(Cl)c2)n2cnnc2)cc1 CHEMBL5418345 pIC50 1.698 nM
N#Cc1ccc(N(CSc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5412353 pIC50 1.698 nM
N#Cc1ccc(N(CCSc2cccc(OS(N)(=O)=O)c2)n2cnnc2)cc1 CHEMBL5435238 pIC50 1.698 nM
N#Cc1ccc(Cn2cncn2)c(-c2ccccc2)c1 CHEMBL589738 IC50 1.7 nM
Oc1ccc(CC(c2ccc(Cl)cc2)n2cncn2)cc1Br CHEMBL5429844 pIC50 1.799 nM
N#Cc1ccc(C(c2ccc(O)c(Br)c2)n2cncn2)cc1 CHEMBL481091 IC50 1.8 nM
Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 CHEMBL104 IC50 1.8 nM
Oc1cc2c(cc1C(c1ccc(F)cc1)n1ccnc1)OCO2 CHEMBL513615 Ki 1.9 nM
N#Cc1ccc(Cn2cncn2)c(-c2ccc(OS(N)(=O)=O)c(Cl)c2)c1 CHEMBL598212 IC50 1.9 nM
COc1ccc2cc(C(O)(c3cccnc3)c3ccc(Cl)cc3Cl)oc2c1 CHEMBL5278036 IC50 1.9 nM
N#Cc1ccc(C2CCc3cncn32)cc1 CHEMBL1203762 IC50 2.0 nM
N#Cc1ccc(Cn2cncn2)cc1-c1ccc(OS(N)(=O)=O)cc1 CHEMBL598199 IC50 2.0 nM
CC1=CC[C@@H]2[C@H]1[C@H]1OC(=O)[C@@H](C)[C@@H]1CC[C@]2(C)O CHEMBL1097371 IC50 2.0 nM
O=c1cc(-c2ccc(O)cc2)oc2cc(O)ccc12 CHEMBL294878 IC50 2.0 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43[C@@H]3CS3)[C@@H]1CCC2=O CHEMBL3752770 Ki 2.0 nM
CCCOc1ccc(C(=O)c2cccc(Cn3ccnc3)c2)cc1 CHEMBL5284760 IC50 2.0 nM
N#Cc1ccc(N(CCc2ccc(OS(N)(=O)=O)c(F)c2)n2cnnc2)cc1 CHEMBL5432233 pIC50 2.0 nM
N#Cc1ccc(N(CCCCSc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5398138 pIC50 2.0 nM
N#Cc1ccc(C2CCc3cncn32)cc1 CHEMBL162585 pIC50 2.0 nM
COc1ccc2oc(C(c3ccc(Cl)cc3)n3cncn3)cc2c1 CHEMBL5186519 IC50 2.01 nM
O=S(=O)(Oc1ccc(C(F)(F)F)cc1)C1CC2OC1C(c1ccc(-n3cncn3)cc1)=C2c1ccc(O)cc1 CHEMBL5405944 IC50 2.09 nM
N#Cc1ccc(N(CCc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5406393 pIC50 2.099 nM
N#Cc1ccc(N(CCCc2ccc(OS(N)(=O)=O)c(Cl)c2)n2cnnc2)cc1 CHEMBL5415771 pIC50 2.099 nM
N#Cc1ccc(N(Cc2ccc3c(Cl)c(OS(N)(=O)=O)ccc3c2)n2cnnc2)cc1 CHEMBL3622063 pIC50 2.099 nM
O=c1c([C@@H](c2ccc([N+](=O)[O-])cc2)n2ccnc2)coc2ccccc12 CHEMBL224665 pIC50 2.291 nM
CC1(C)C[C@@]2(C)C(=CC1=O)CCC1C2CC[C@]2(C)C(=O)CCC12 CHEMBL421018 Ki 2.3 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(Cl)c2)n2cnnc2)cc1 CHEMBL322322 IC50 2.3 nM
O=c1c(C(c2ccc([N+](=O)[O-])cc2)n2ccnc2)coc2ccccc12 CHEMBL516643 IC50 2.3 nM
Cn1cc(CCN(c2ccc(C#N)cc2)n2cnnc2)c2cc(OS(N)(=O)=O)ccc21 CHEMBL3622066 IC50 2.3 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(Sc2ccccc2)c1 CHEMBL3622069 IC50 2.3 nM
Cc1c(-c2nocc2C(=O)SC#N)c(=O)n(-c2ccccc2)n1C CHEMBL5195433 IC50 2.3 nM
Cc1c(-c2nocc2SC#N)c(=O)n(-c2ccccc2)n1C CHEMBL5281972 IC50 2.3 nM
Oc1ccc(C(c2ccc(Cl)cc2)n2cncn2)cc1Br CHEMBL5410011 pIC50 2.301 nM
N#Cc1ccc(N(Cc2c(Cl)cc(O)cc2Cl)n2cnnc2)cc1 CHEMBL5402384 pIC50 2.301 nM
O=c1c(-c2ccccc2)c(SCc2ccncc2)oc2cc(OCc3ccccc3)ccc12 CHEMBL188664 Log IC50 2.33 nM
COc1ccc(-c2c(SCc3ccncc3)oc3cc(O)ccc3c2=O)cc1 CHEMBL187068 Log IC50 2.34 nM
CN(C)S(=O)(=O)Oc1ccc(-c2cc(Cn3cncn3)ccc2C#N)cc1Cl CHEMBL599238 IC50 2.4 nM
O=c1c(-c2ccc(O)cc2)c(SCc2ccncc2)oc2cc(O)ccc12 CHEMBL185950 Log IC50 2.44 nM
N#Cc1ccc(N(Cc2ccc(O)c(Cl)c2)n2cnnc2)cc1 CHEMBL226789 IC50 2.5 nM
CC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3752165 Ki 2.5 nM
CCC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3754546 Ki(app) 2.5 nM
CCCC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3753803 Ki 2.5 nM
CCCCC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3752011 Ki 2.5 nM
CCCCCC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3752619 Ki 2.5 nM
CCCCCCC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3752315 Ki 2.5 nM
CCCCCCCC1=C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3752341 Ki 2.5 nM
C[C@]12C=CC(=O)C=C1C=C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL2311178 Ki 2.5 nM
N#Cc1ccc(N(CCCc2ccc(OS(N)(=O)=O)c(F)c2)n2cnnc2)cc1 CHEMBL5397197 pIC50 2.5 nM
NS(=O)(=O)Oc1ccc(C(c2ccc(Cl)cc2)n2cncn2)cc1Br CHEMBL5429338 pIC50 2.5 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)cc2Br)n2cnnc2)cc1 CHEMBL5413431 pIC50 2.6 nM
N#Cc1ccc(N(CCn2ccc3cc(OS(N)(=O)=O)ccc32)n2cnnc2)cc1 CHEMBL3622065 pIC50 2.698 nM
COc1ccc(-c2c(SCc3ccncc3)oc3cc(OCc4ccccc4)ccc3c2=O)cc1 CHEMBL186079 Log IC50 2.72 nM
CCC#CCOc1ccc2cc(C(c3ccc(Cl)cc3)n3cncn3)oc2c1 CHEMBL5205534 IC50 2.76 nM
O=c1c(-c2ccccc2)c(SCc2ccncc2)oc2cc(O)ccc12 CHEMBL184749 Log IC50 2.79 nM
N#Cc1ccc(C(Cc2ccc(OS(N)(=O)=O)cc2)n2cncn2)cc1 CHEMBL5395753 pIC50 2.799 nM
N#Cc1ccc(N(Cc2cccc(O)c2)n2cnnc2)cc1 CHEMBL390078 IC50 2.8 nM
COc1cc(CN(c2ccc(C#N)cc2)n2cnnc2)ccc1O CHEMBL226791 IC50 2.8 nM
CCCCC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3752650 Ki(app) 2.8 nM
CCCCCC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3754285 Ki(app) 2.8 nM
CCCCCCCC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3754366 Ki(app) 2.8 nM
N#Cc1ccc(C(Cc2ccc(O)cc2)n2cncn2)cc1 CHEMBL5421626 pIC50 2.897 nM
N#Cc1ccc2c(c1)CCC=C2n1ccnc1 CHEMBL31224 pIC50 2.897 nM
CCC[C@H]1CC2C(CCC3(C)C(O)CCC23)C2(C)CCCC=C12 CHEMBL69891 Ki app 2.9 nM
N#Cc1ccc(N(Cc2ccc(O)c(F)c2)n2cnnc2)cc1 CHEMBL226738 IC50 2.9 nM
COc1cc(CN(c2ccc(C#N)cc2)n2cnnc2)cc(Cl)c1OS(N)(=O)=O CHEMBL390717 IC50 2.9 nM
O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O)cc(O)c21 CHEMBL9352 IC50 2.9 nM
N#Cc1ccc(N(CCCOc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5423400 pIC50 2.999 nM
N#Cc1ccc(N(Cc2ccc(O)cc2Cl)n2cnnc2)cc1 CHEMBL5431758 pIC50 2.999 nM
C=C[C@]12CCC(=O)C=C1CCC1C2CC[C@]2(C)C(=O)CCC12 CHEMBL98685 Ki 3.0 nM
N#Cc1ccc(C(c2ccc(OS(N)(=O)=O)c(Br)c2)n2cncn2)cc1 CHEMBL518761 IC50 3.0 nM
N#Cc1ccc(C(c2ccc(C#N)cc2)n2ccnc2)cc1 CHEMBL29482 IC50 3.0 nM
CCn1ccc2c3c(Cn4ccnc4)cc(-c4ccccc4)nc3ccc21 CHEMBL2442760 IC50 3.1 nM
C[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCCC=C12 CHEMBL3751881 Ki 3.1 nM
Cc1cnccc1-c1nc(-c2cccnc2)cs1 CHEMBL1957218 Ki 3.17 nM
N#Cc1ccc(N(CCn2ccc3cc(O)ccc32)n2cnnc2)cc1 CHEMBL5434606 pIC50 3.199 nM
N#Cc1ccc([C@@H]2CCCc3cncn32)cc1 CHEMBL31215 IC50 3.2 nM
N#Cc1ccc([C@H](c2ccc(OS(N)(=O)=O)c(Br)c2)n2cncn2)cc1 CHEMBL479559 IC50 3.2 nM
N#Cc1ccc([C@@H]2CCCc3cncn32)cc1 CHEMBL481092 IC50 3.2 nM
COc1ccc2c(=O)c(-c3ccccc3)c(SCc3ccncc3)oc2c1 CHEMBL185809 Log IC50 3.21 nM
Cc1c(-c2csc(Cl)n2)c(=O)n(-c2ccccc2)n1C CHEMBL5271636 IC50 3.3 nM
N#CC1(c2cc(Cn3cncn3)cc(Sc3ccc(OS(N)(=O)=O)cc3)c2)CC1 CHEMBL3622075 pIC50 3.396 nM
C[C@]12CC[C@H]3[C@@H](CC=C4[C@@H](O)CCC[C@@]43CO)[C@@H]1CCC2=O CHEMBL1630274 Ki app 3.4 nM
N#Cc1ccc([C@@H](c2ccc(O)c(Br)c2)n2cncn2)cc1 CHEMBL500976 IC50 3.4 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43[C@@H]3CN3)[C@@H]1CCC2=O CHEMBL3752276 Ki 3.4 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43[C@H]3CN3)[C@@H]1CCC2=O CHEMBL3752897 Ki 3.4 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43[C@@H]3CN3)[C@@H]1CC[C@@H]2O CHEMBL3754519 Ki 3.4 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43[C@H]3CN3)[C@@H]1CC[C@@H]2O CHEMBL3752403 Ki 3.4 nM
CCC1(c2ccc(N)cc2)CCC(=O)NC1=O CHEMBL488 Log IC50 3.45 nM
COc1ccc2c(=O)c(-c3ccc(C)cc3)c(SCc3ccncc3)oc2c1 CHEMBL184051 Log IC50 3.48 nM
O=S(=O)(Oc1ccc(Br)cc1)C1CC2OC1C(c1ccc(-n3cncn3)cc1)=C2c1ccc(O)cc1 CHEMBL5421409 IC50 3.48 nM
COc1ccc(-c2c(SCc3ccncc3)oc3cc(OC)ccc3c2=O)cc1 CHEMBL361653 Log IC50 3.49 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(Sc2ccc(OS(N)(=O)=O)cc2)c1 CHEMBL3622070 pIC50 3.499 nM
COc1ccc2c(c1)C(N)=C(CC1=CCNC=C1)C2=O CHEMBL1096024 IC50 3.5 nM
O=c1c(-c2ccccc2)c(SCc2cccnc2)oc2cc(O)ccc12 CHEMBL364326 Log IC50 3.56 nM
N#Cc1ccc(N(Cc2ccc3c(Cl)c(O)ccc3c2)n2cnnc2)cc1 CHEMBL5398997 pIC50 3.802 nM
Cn1nnc2ccc(C(c3ccc(O)cc3)n3cncn3)cc21 CHEMBL5421450 pIC50 3.802 nM
N#Cc1ccc(N(CSc2cccc(OS(N)(=O)=O)c2)n2cnnc2)cc1 CHEMBL5428080 pIC50 3.899 nM
N#Cc1ccc(N(Cc2ccc(O)cc2F)n2cnnc2)cc1 CHEMBL5436006 pIC50 3.899 nM
N#Cc1ccc(N(Cc2ccc(Br)c(OS(N)(=O)=O)c2)n2cnnc2)cc1 CHEMBL226893 IC50 3.9 nM
COc1ccc2c(=O)c(-c3ccccc3)c(SCc3cccnc3)oc2c1 CHEMBL185819 Log IC50 3.96 nM
O=c1c2ccccc2sc2c(Cn3ccnc3)cccc12 CHEMBL1083353 IC50 3.98 nM
N#Cc1ccc(N(CCc2coc3cc(OS(N)(=O)=O)ccc23)n2cnnc2)cc1 CHEMBL5408847 pIC50 3.999 nM
N#Cc1ccc(N(CCc2c(F)cc(OS(N)(=O)=O)cc2F)n2cnnc2)cc1 CHEMBL5404624 pIC50 3.999 nM
C#CC[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL2105261 Ki 4.0 nM
N#Cc1ccc(N(CCc2coc3ccc(OS(N)(=O)=O)cc23)n2cnnc2)cc1 CHEMBL3622067 IC50 4.0 nM
c1cncc(-c2csc(-c3cccnc3)n2)c1 CHEMBL118266 IC50 4.0 nM
C1=C(c2cccnc2)CCc2ccccc21 CHEMBL205881 IC50 4.073 nM
CC#CCOc1ccc2cc(C(c3ccc(F)cc3)n3cncn3)oc2c1 CHEMBL5173597 IC50 4.1 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(Sc2ccc(OS(N)(=O)=O)c(Cl)c2)c1 CHEMBL3622071 pIC50 4.198 nM
O=S(=O)(Oc1cccc2ccccc12)C1CC2OC1C(c1ccc(-n3ccnc3)cc1)=C2c1ccc(O)cc1 CHEMBL5411799 IC50 4.3 nM
N#Cc1ccc(N(CCCCOc2ccc(O)cc2)n2cnnc2)cc1 CHEMBL5411472 pIC50 4.395 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(C(F)F)c2)n2cnnc2)cc1 CHEMBL5395694 pIC50 4.395 nM
COc1ccc(-c2coc3cc(O)cc(O)c3c2=O)cc1 CHEMBL131921 Log IC50 4.53 nM
CCC[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL282673 Ki 4.6 nM
N#Cc1cc(Cn2cncn2)ccc1-c1ccccc1 CHEMBL608153 IC50 4.6 nM
C=C1C=C2CCC3C(CC[C@]4(C)C(=O)CCC34)[C@@]2(C)CC1 CHEMBL98105 Ki 4.7 nM
CC[C@@H]1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 CHEMBL8313 Ki app 4.7 nM
CC[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL24021 Ki 4.7 nM
CC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3753810 Ki(app) 4.7 nM
Oc1ccc(C(=C(Cn2ccnc2)c2ccccc2)c2ccc(O)cc2)cc1 CHEMBL4777271 IC50 4.77 nM
C/C=C1\C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3753629 Ki 4.9 nM
CCC#CCOc1ccc2cc(C(O)(c3ccc(Br)cc3)c3cccnc3)oc2c1 CHEMBL5277776 IC50 4.9 nM
FC(F)(F)c1ccc(-n2c(Cn3ccnc3)cc3ccccc32)cc1 CHEMBL2336859 IC50 4.93 nM
Nc1ccc(C23CC2C(=O)N(CC2CCCCC2)C3=O)cc1 CHEMBL281947 IC50 5.0 nM
O=c1cc(-c2ccccc2)oc2c1ccc1ccc(O)cc12 CHEMBL329500 Ki 5.0 nM
CCCCC[C@@H]1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 CHEMBL440832 Ki app 5.0 nM
Clc1cccc(C(c2ccc3[nH]cnc3c2)n2ccnc2)c1 CHEMBL389433 IC50 5.0 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(Sc2ccc(OS(N)(=O)=O)c(Br)c2)c1 CHEMBL3622072 IC50 5.0 nM
CCCCC[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12 CHEMBL3752065 Ki(app) 5.0 nM
C[C@]12CCC(=O)C=C1[C@@H]1[C@H]([C@@H]3[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]32)C1(F)F CHEMBL3754061 Ki 5.0 nM
C[C@]12CC[C@H]3[C@@H]([C@H]4[C@@H](C5=CCCC[C@@]53C)C4(F)F)[C@@H]1CC[C@@H]2O CHEMBL3753845 Ki 5.0 nM
C[C@]12CCCC=C1[C@@H]1[C@H]([C@@H]3[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]32)C1(F)F CHEMBL3753196 Ki 5.0 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CN=[N+]=[N-])[C@@H]1CCC2=O CHEMBL3752954 Ki 5.0 nM
C=C[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL24410 Ki 5.1 nM
C=C[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3753920 Ki 5.1 nM
N#Cc1ccc(N(CC2CCc3cc(OS(N)(=O)=O)ccc3C2)n2cnnc2)cc1 CHEMBL3622061 IC50 5.2 nM
Nc1ccc(C(Cn2ccnc2)=C(c2ccc(O)cc2)c2ccc(O)cc2)cc1 CHEMBL4755831 IC50 5.24 nM
O=C(c1ccc(-c2ccccc2)cc1)c1cccc(Cn2ccnc2)c1 CHEMBL243961 IC50 5.3 nM
CCn1ccc2c3nc(-c4ccccc4)cc(Cn4ccnc4)c3ccc21 CHEMBL2442758 IC50 5.3 nM
C[C@@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCCC=C12 CHEMBL3754711 Ki 5.3 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(Oc2ccc(OS(N)(=O)=O)cc2)c1 CHEMBL3622076 pIC50 5.495 nM
N#Cc1ccc(N(CSc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5425142 pIC50 5.495 nM
N#Cc1ccc(N(CCCCCCCCCCSc2ccc(OS(N)(=O)=O)cc2)n2cnnc2)cc1 CHEMBL5409338 pIC50 5.495 nM
CN(CCN(c1ccc(C#N)cc1)n1cnnc1)S(=O)(=O)c1ccc(O)cc1 CHEMBL5427905 pIC50 5.495 nM
CCC[C@@H]1CC2C(CCC3(C)C(O)CCC23)C2(C)CCCC=C12 CHEMBL73071 Ki app 5.5 nM
N#Cc1ccc(C(c2ccc(O)c(Cl)c2)n2cncn2)cc1 CHEMBL479385 IC50 5.5 nM
O=[N+]([O-])c1ccc(Cn2ccnc2)c(Sc2ccccc2)c1 CHEMBL1085936 IC50 5.59 nM
C[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL25588 Ki 5.6 nM
Oc1cc2c(cc1C(c1ccc3c(c1)OCO3)n1ccnc1)OCO2 CHEMBL459503 Ki 5.6 nM
Oc1ccc2oc(C(c3ccc(Cl)cc3)n3cncn3)cc2c1 CHEMBL5178202 IC50 5.67 nM
N#Cc1ccc(C(c2ccc(C#N)cc2)n2ncnn2)cc1 CHEMBL224790 pIC50 5.754 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CCCC[C@@]43CO)[C@@H]1CCC2=O CHEMBL1629805 Ki app 5.8 nM
C[C@]12CCCC=C1[C@H](O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL1630261 Ki app 6.0 nM
CC(C)(C#N)c1cc(Cn2cncn2)cc(-c2ccc(O)cc2)c1 CHEMBL605418 IC50 6.0 nM
O=C1OC[C@H](Cc2ccc(O)c(O)c2)[C@H]1Cc1ccc(O)c(O)c1 CHEMBL369471 IC50 6.0 nM
O=C1OC[C@H](Cc2ccccc2)[C@H]1Cc1cccc(O)c1 CHEMBL1094154 IC50 6.0 nM
Cc1cc(Cn2ccnc2)c2ccc3[nH]ccc3c2n1 CHEMBL2442759 IC50 6.0 nM
COc1ccc(S(=O)(=O)N2CCCC(Cn3ccnc3)C2)cc1Br CHEMBL3805814 IC50 6.0 nM
COc1ccc2cc(Cn3ccnc3)n(-c3ccccc3)c2c1 CHEMBL2336847 IC50 6.23 nM
Cc1ccc(C(c2ccc(C)cc2)n2ccnc2)cc1 CHEMBL135381 pIC50 6.397 nM
COc1ccc(C(Cn2ccnc2)Sc2ccc(Cl)c(Cl)c2)cc1 CHEMBL459502 Ki 6.5 nM
N#Cc1ccc(N(Cc2ccc(O)c(F)c2F)n2cnnc2)cc1 CHEMBL5401946 pIC50 6.699 nM
CCC[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL25695 Ki 6.7 nM
COc1ccc(C2=C(c3ccc(OC)c(OC)c3)C(=O)OC2)cc1 CHEMBL1096439 IC50 6.9 nM
CCCCOc1ccc(-n2ccnc2)cc1 CHEMBL112532 pIC50 6.998 nM
C[C@]12CCC3C(CCC4=CC(=O)CC[C@]43C3CO3)C1CCC2=O CHEMBL26093 Ki 7.0 nM
CCC[C@@H]1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 CHEMBL8254 Ki app 7.0 nM
C=C1C(=O)O[C@@H]2[C@H]3C(C)=CC[C@H]3CCC[C@@H]12 CHEMBL1099308 IC50 7.0 nM
N#Cc1ccc(Cn2ccnc2)cc1 CHEMBL349822 IC50 7.0 nM
CCCCCC(=O)O[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3752998 Ki 7.0 nM
C[C@]12CCC(=O)C=C1[C@@H](OCc1ccccc1)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3752038 Ki 7.0 nM
C[C@]12C=CC(=O)C=C1C[C@@H](Cc1ccccc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3752591 Ki(app) 7.0 nM
C[C@]12C=CC(=O)C=C1C[C@@H](CCc1ccccc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3754259 Ki(app) 7.0 nM
C[C@]12C=CC(=O)C=C1C[C@@H](CCCc1ccccc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3753447 Ki(app) 7.0 nM
C[C@]12C=CC(=O)C=C1C[C@@H](CCc1ccc([N+](=O)[O-])cc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3752221 Ki(app) 7.0 nM
C[C@]12C=CC(=O)C=C1C[C@@H](CCc1ccc(N)cc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3754055 Ki(app) 7.0 nM
C[C@]12C=CC(=O)C=C1C[C@@H](CCCc1ccc([N+](=O)[O-])cc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3753373 Ki(app) 7.0 nM
O=S(=O)(c1ccc2nsnc2c1)N1CCCC(Cn2ccnc2)C1 CHEMBL3805851 IC50 7.0 nM
N#Cc1ccccc1-c1cccc(Cn2cncn2)c1 CHEMBL5438879 pIC50 7.015 nM
N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(F)c2F)n2cnnc2)cc1 CHEMBL5411834 pIC50 7.096 nM
N#Cc1ccc(C(c2ccc(O)cc2)n2cncn2)cc1 CHEMBL519937 IC50 7.2 nM
O=C(c1ccccc1)c1cccc(Cn2ccnc2)c1 CHEMBL397728 IC50 7.3 nM
Nc1ccc(SC[C@@H]2CO[C@](CCc3ccc(Cl)cc3)(Cn3ccnc3)O2)cc1 CHEMBL70611 Ki 7.6 nM
Brc1ccc(C2CCCc3cncn32)cc1 CHEMBL1203766 IC50 7.6 nM
N#Cc1ccc(N(Cc2cc(Cl)c(O)c(Cl)c2)n2cnnc2)cc1 CHEMBL226843 IC50 7.6 nM
Brc1ccc(C2CCCc3cncn32)cc1 CHEMBL350338 pIC50 7.603 nM
N#Cc1ccc(/C(=N\c2ccc(Br)cc2)n2ccnc2)cc1 CHEMBL31456 pIC50 7.691 nM
CCCCCCC[C@@H]1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 CHEMBL268918 Ki app 7.8 nM
O=S(=O)(Oc1ccc(Cl)cc1)C1CC2OC1C(c1ccc(-n3cncn3)cc1)=C2c1ccc(O)cc1 CHEMBL5408038 IC50 7.8 nM
CCCCCC[C@@H]1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 CHEMBL266350 Ki app 8.0 nM
O=c1cc(-c2ccccc2)oc2ccccc12 CHEMBL275638 IC50 8.0 nM
N#Cc1ccc(C(c2ccc(C#N)cc2)n2ccnn2)cc1 CHEMBL224789 IC50 8.0 nM
Clc1ccc(/C=C(\Cn2ccnn2)c2ccc(Cl)cc2)cc1 CHEMBL4441579 Ki 8.0 nM
Clc1cc(-c2nc(-c3cccnc3)cs2)ccn1 CHEMBL1957216 Ki 8.2 nM
CC[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3754719 Ki 8.2 nM
CC[C@]12C=CC(=O)C=C1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]12 CHEMBL3752973 Ki 8.2 nM
CC[C@]12CCC(=O)C=C1C=C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3753667 Ki 8.2 nM
CC[C@]12C=CC(=O)C=C1C=C[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]12 CHEMBL3752460 Ki 8.2 nM
COc1ccc(C(c2ccc(Cl)cc2)n2ccnc2)cc1 CHEMBL135063 pIC50 8.395 nM
C[C@]12C=CC(=O)C=C1C(CCc1ccccc1)=C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3752155 Ki(app) 8.5 nM
O=c1cc(-c2ccccc2)oc2cc(O)c(O)cc12 CHEMBL300814 IC50 8.7 nM
Clc1ccc(C(c2ccc(Cl)cc2)n2cncn2)cc1 CHEMBL341386 pIC50 8.79 nM
CCCC[C@@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 CHEMBL24037 Ki 8.8 nM
Clc1ccc(C(c2cc3ccccc3o2)n2ccnc2)cc1 CHEMBL1097980 IC50 8.8 nM
CC1(C)C[C@@]2(C)C(=CC1=O)CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3753169 Ki 8.8 nM
CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(N)cc1 CHEMBL3948254 IC50 8.8 nM
Brc1ccc(C(c2ccc(Br)cc2)n2ccnc2)cc1 CHEMBL436369 pIC50 8.892 nM
CCCCC[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12 CHEMBL305630 IC50 9.0 nM
CC[C@]12CCC(=O)C=C1CCC1C2CC[C@]2(C)C(=O)CCC12 CHEMBL319108 Ki 9.0 nM
Clc1ccc(C(c2ccc3[nH]ccc3c2)n2ccnc2)cc1 CHEMBL204039 IC50 9.0 nM
C[C@]12CCC(=O)C=C1C(Cc1ccccc1)=C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3754168 Ki(app) 9.0 nM
O=[N+]([O-])c1cccc(Cl)c1Oc1cccc(S(=O)(=O)N2CCCC(Cn3ccnc3)C2)c1 CHEMBL3806301 IC50 9.0 nM
COc1ccc(S(=O)(=O)N2CCCC(Cn3ccnc3)C2)cc1C(C)(C)C CHEMBL1784801 IC50 9.0 nM
CCC#CCOc1ccc(C(=O)c2cccc(Cn3ccnc3)c2)cc1 CHEMBL5283276 IC50 9.0 nM
Fc1ccc(-n2c(Cn3ccnc3)cc3ccccc32)cc1 CHEMBL2336856 IC50 9.01 nM
O=[N+]([O-])c1ccc(N(Cc2ccc(Cl)cc2)n2cnnc2)cc1Br CHEMBL4574913 pIC50 9.016 nM
Clc1ccc(C(c2ccc(Cl)cc2)n2cnnc2)cc1 CHEMBL135563 pIC50 9.29 nM
CCCCC[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3752625 Ki(app) 9.3 nM
CCCCCC[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3754063 Ki(app) 9.3 nM
CCCCCCCC[C@H]1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)CCC(=O)C=C12 CHEMBL3751897 Ki(app) 9.3 nM
Clc1ccc(C(c2ccc(Cl)cc2)(c2ncc[nH]2)n2ccnc2)cc1 CHEMBL137604 pIC50 9.397 nM
OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cscn1 CHEMBL5410623 pIC50 9.594 nM
C[C@]12C=CC(=O)C(Sc3ccccc3)=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3752288 Ki 9.8 nM
C[C@]12CCC(=O)C(Sc3ccccc3)=C1C=C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3753109 Ki 9.8 nM
C[C@]12C=CC(=O)C(Sc3ccccc3)=C1C=C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3752174 Ki 9.8 nM
C[C@]12C=CC(=O)C=C1C[C@@H](Sc1ccc(N)cc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3349548 Ki 9.9 nM
C[C@]12C=CC(=O)C=C1C[C@H](c1ccc(N)cc1)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL5286289 pIC50 9.908 nM