COc1ccc2c(c(OC)cc3c(=O)cc(-c4ccc(F)cc4)oc32)c1OC CHEMBL4467401 IC50 1.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc4[nH]ncc4c3)oc12 CHEMBL4759437 IC50 1.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(Cl)cn3)oc12 CHEMBL4798651 IC50 1.6 nM
COc1ccc(/C=C/c2c(OC)cccc2OC)c(OC)c1 CHEMBL3132932 IC50 1.77 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(Cl)cc3)oc12 CHEMBL3422338 IC50 1.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(F)n3)oc12 CHEMBL4799247 IC50 2.3 nM
COc1cc(-c2cc(=O)c3ccc4ccccc4c3o2)cc(OC)c1OC CHEMBL4457289 IC50 3.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cscn3)oc12 CHEMBL4781932 IC50 3.1 nM
COc1ccc(/C=C/c2c(OC)ccc(OC)c2OC)c(OC)c1 CHEMBL3220150 IC50 3.3 nM
COc1ccc(OC)c(/C=C/c2ccc(OC)cc2OC)c1 CHEMBL3220144 IC50 3.51 nM
O=c1cc(-c2ccc(Cl)cc2)oc2c1ccc1ccccc12 CHEMBL425868 IC50 4.3 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccs3)oc12 CHEMBL4746097 IC50 4.4 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccc3)oc12 CHEMBL3422257 IC50 4.8 nM
COc1ccc(/C=C/c2c(OC)cc(OC)cc2OC)c(OC)c1 CHEMBL3220149 IC50 4.93 nM
O=c1cc(-c2cccc(Cl)c2)oc2c1ccc1ccccc12 CHEMBL368236 IC50 5.2 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccn3)oc12 CHEMBL4755282 IC50 5.4 nM
COc1ccc(/C=C/c2cc(OC)c(OC)cc2OC)c(OC)c1 CHEMBL3220148 IC50 5.46 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(Cl)n3)oc12 CHEMBL4759410 IC50 5.7 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccc3F)oc12 CHEMBL3422258 IC50 5.9 nM
COc1cc(/C=C/c2ccc(OC)cc2OC)cc(OC)c1 CHEMBL46909 IC50 6.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(Cl)c3)oc12 CHEMBL3422337 IC50 6.4 nM
O=c1cc(-c2ccc(F)cc2)oc2c1ccc1ccccc12 CHEMBL359819 IC50 6.7 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cncc(C)c3)oc12 CHEMBL4791264 IC50 6.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccnc3)oc12 CHEMBL4781895 IC50 7.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cncc(Br)c3)oc12 CHEMBL4750829 IC50 8.0 nM
COc1ccc(/C=C/c2ccc(OC)cc2OC)c(OC)c1 CHEMBL3220145 IC50 8.81 nM
O=c1cc(-c2ccc(Cl)cc2)sc2c1ccc1ccccc12 CHEMBL4471231 IC50 9.0 nM
[N-]=[N+]=Nc1ccc(-c2cc(=O)c3ccc4ccccc4c3o2)cc1 CHEMBL4474660 IC50 9.5 nM
S=c1cc(-c2ccc(Cl)cc2)oc2c1ccc1ccccc12 CHEMBL4474545 IC50 9.6 nM
CN(C)c1cccc(-c2cc(=O)c3ccc4ccccc4c3o2)c1 CHEMBL4558857 IC50 9.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(F)cc3)oc12 CHEMBL3422335 IC50 9.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(Cl)ccn3)oc12 CHEMBL4798694 IC50 9.9 nM
O=c1cc(-c2ccccc2)oc2c1ccc1ccccc12 CHEMBL283196 IC50 10.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc4ccccc4o3)oc12 CHEMBL4747913 IC50 10.1 nM
COc1cc2c(=O)cc(-c3ccc(F)cc3)[nH]c2c2c(OC)cccc12 CHEMBL4539787 IC50 10.5 nM
c1cn(-c2ccc(Nc3nc(-c4nccs4)cs3)cc2)cn1 CHEMBL5279681 IC50 10.68 nM
COc1ccc(-c2cc(=O)c3cc(OC)c4c(OC)ccc(OC)c4c3o2)cc1OC CHEMBL3422341 IC50 11.5 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(F)c3)oc12 CHEMBL3421639 IC50 11.5 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3ccc(F)cc3)oc12 CHEMBL3422350 IC50 11.8 nM
O=c1cc(-c2ccc(F)c(F)c2)oc2c1ccc1ccccc12 CHEMBL4062213 IC50 11.8 nM
COc1c2ccoc2c(OC)c2oc(=O)ccc12 CHEMBL140796 Ki 12.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccc3O)oc12 CHEMBL3422346 IC50 12.1 nM
O=c1cc(-c2ccccc2F)oc2c1ccc1ccccc12 CHEMBL361608 IC50 12.2 nM
Fc1ccc(-c2cc(=S)c3ccc4ccccc4c3o2)cc1 CHEMBL4465703 IC50 12.3 nM
COc1ccc(-c2cc(=O)c3cc(OC)c4c(OC)ccc(OC)c4c3o2)cc1 CHEMBL3422340 IC50 12.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOC(=O)CN)c(-c3cccc(F)c3)oc12 CHEMBL3422354 IC50 13.6 nM
C=C=C[C@H]1CC[C@H](c2cc(=O)c3ccc4ccccc4c3o2)CC1 CHEMBL4579760 IC50 13.6 nM
O=c1cc(-c2cccc(Cl)c2)sc2c1ccc1ccccc12 CHEMBL4438763 IC50 13.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccco3)oc12 CHEMBL4744690 IC50 13.8 nM
COc1cccc(/C=C/c2ccc(OC)cc2OC)c1 CHEMBL3220143 IC50 15.2 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccnc(N)c3)oc12 CHEMBL4740802 IC50 15.3 nM
COc1ccc(/C=C/c2ccccc2OC)c(OC)c1 CHEMBL2043279 IC50 15.5 nM
CC(=O)S[C@H]1CC[C@H](c2cc(=O)c3ccc4ccccc4c3o2)CC1 CHEMBL4547387 IC50 15.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3c[nH]c4ccccc34)oc12 CHEMBL4753083 IC50 16.5 nM
O=c1cc(-c2cccc(F)c2)oc2c1ccc1ccccc12 CHEMBL436080 IC50 16.7 nM
O=c1cc(-c2cccc(C(F)(F)F)c2)oc2c1ccc1ccccc12 CHEMBL4064195 IC50 16.7 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(F)cn3)oc12 CHEMBL4749123 IC50 16.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cncc(F)c3)oc12 CHEMBL4759778 IC50 17.7 nM
O=c1cc(-c2ccncc2)oc2c1ccc1ccccc12 CHEMBL177991 IC50 18.7 nM
COc1ccccc1-c1cc(=O)c2cc(OC)c3c(OC)ccc(OC)c3c2o1 CHEMBL3422339 IC50 18.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cncc(N)c3)oc12 CHEMBL4741985 IC50 18.8 nM
COc1c(-c2ccccc2)oc2c(ccc3ccoc32)c1=O CHEMBL4282750 Ki 19.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccc3Cl)oc12 CHEMBL3422336 IC50 19.2 nM
Cc1c2ccncc2c(C)c2c1[nH]c1ccccc12 CHEMBL123 IC50 19.3 nM
COc1cc2c(=O)cc(-c3cccc(Br)c3)[nH]c2c2c(OC)cccc12 CHEMBL4532099 IC50 19.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(C)n3)oc12 CHEMBL4750507 IC50 19.9 nM
COc1c(-c2ccc3c(c2)OCO3)oc2c(ccc3occc32)c1=O CHEMBL577397 IC50 20.0 nM
O=c1cc(-c2ccccc2)oc2c1ccc1occc12 CHEMBL224157 IC50 20.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOCCOCCOCCOC(=O)CN)c(-c3cccc(F)c3)oc12 CHEMBL3422358 IC50 20.16 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc4ncccc4c3)oc12 CHEMBL4753629 IC50 20.9 nM
c1cncc(-c2csc(-c3csc(Nc4ccc(N5CCOCC5)cc4)n3)n2)c1 CHEMBL5290901 IC50 22.35 nM
COc1cc(-c2cc(=O)c3cc(OC)c4c(OC)ccc(OC)c4c3o2)cc(OC)c1OC CHEMBL3422342 IC50 22.5 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3c[nH]c4ncccc34)oc12 CHEMBL4795310 IC50 23.8 nM
COc1ccc(/C=C/c2ccccc2)c(OC)c1 CHEMBL3219852 IC50 25.0 nM
COc1ccc(-c2nc(-c3cccnc3)cs2)c(OC)c1 CHEMBL5406710 IC50 25.0 nM
Fc1cccc(-c2cc(=S)c3ccc4ccccc4c3o2)c1 CHEMBL4556419 IC50 25.1 nM
O=c1cc(-c2cccnc2)oc2c1ccc1ccccc12 CHEMBL177938 IC50 25.3 nM
O=c1cc(-c2cc(Cl)cc(Cl)c2)oc2c1ccc1ccccc12 CHEMBL4545007 IC50 25.5 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3ccc(Cl)cc3)oc12 CHEMBL3422353 IC50 26.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccnc(Br)c3)oc12 CHEMBL4782753 IC50 26.9 nM
[N-]=[N+]=Nc1cccc(-c2cc(=O)c3ccc4ccccc4c3o2)c1 CHEMBL4514232 IC50 27.1 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3ccccc3F)oc12 CHEMBL3422348 IC50 27.5 nM
COc1cc(-c2cc(=S)c3ccc4ccccc4c3o2)cc(OC)c1OC CHEMBL4483482 IC50 28.2 nM
COc1c(-c2ccccc2)oc2c(ccc3occc32)c1=O CHEMBL208484 IC50 30.0 nM
Fc1cccc(Nc2nc(-c3nc(-c4cccnc4)cs3)cs2)c1 CHEMBL5287897 IC50 30.31 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(N)nc3)oc12 CHEMBL4745341 IC50 30.8 nM
COc1ccc(-c2cc(=O)c3ccc4ccccc4c3o2)cc1 CHEMBL2420082 IC50 30.9 nM
O=c1cc(-c2cccc(N3CCOCC3)c2)oc2c1ccc1ccccc12 CHEMBL4532886 IC50 30.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3ccccc3)oc12 CHEMBL3422347 IC50 31.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccncc3N)oc12 CHEMBL4746873 IC50 31.6 nM
S=c1cc(-c2cccc(Cl)c2)oc2c1ccc1ccccc12 CHEMBL4553927 IC50 31.7 nM
Fc1ccccc1-c1cc(=S)c2ccc3ccccc3c2o1 CHEMBL4562047 IC50 31.9 nM
Oc1c2ccccc2nc2c3nc4ccccc4c-3ccn12 CHEMBL413956 IC50 32.0 nM
O/N=c1\cc(-c2ccccc2)oc2c1ccc1ccccc12 CHEMBL4434863 IC50 32.1 nM
O=c1cc(-c2ccccc2)sc2c1ccc1ccccc12 CHEMBL4568026 IC50 32.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3ccccc3Cl)oc12 CHEMBL3422351 IC50 32.9 nM
C=C=C[C@H]1CC[C@@H](c2cc(=O)c3ccc4ccccc4c3o2)CC1 CHEMBL4541853 IC50 33.0 nM
CN1CCN(c2cccc(-c3cc(=O)c4ccc5ccccc5c4o3)c2)CC1 CHEMBL4585810 IC50 34.6 nM
COc1cccc(-c2cc(=O)c3ccc4ccccc4c3o2)c1 CHEMBL3230194 IC50 35.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOCCOCCOC(=O)CN)c(-c3cccc(F)c3)oc12 CHEMBL3421640 IC50 36.16 nM
CN1CCN(c2cc(Cl)cc(-c3cc(=O)c4ccc5ccccc5c4o3)c2)CC1 CHEMBL4518052 IC50 37.9 nM
O=c1cc(-c2ccccn2)oc2c1ccc1ccccc12 CHEMBL4466261 IC50 37.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccnc(F)c3)oc12 CHEMBL4799346 IC50 38.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(Br)cn3)oc12 CHEMBL4753119 IC50 38.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOC(=O)[C@H](C)N)c(-c3cccc(F)c3)oc12 CHEMBL3422355 IC50 39.4 nM
O=c1cc(-c2ccccc2)oc2c1ccc1ncccc12 CHEMBL3601435 Ki 40.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccncc3)oc12 CHEMBL4744264 IC50 40.4 nM
c1cc2ccc3cccc4ccc(c1)c2c34 CHEMBL279564 IC50 41.0 nM
C#CCOc1ccc(-c2cc(=O)c3c(ccc4ccccc43)o2)cc1 CHEMBL2347919 IC50 41.0 nM
COc1cc(/C=C/c2cccs2)cc(OCCn2ccnc2)c1 CHEMBL4447260 IC50 41.0 nM
COc1ccc(/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 CHEMBL3132926 IC50 41.8 nM
O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12 CHEMBL117 Ki 42.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc4[nH]cnc4c3)oc12 CHEMBL4745122 IC50 42.4 nM
O=c1cc(-c2ccc(O)cc2)oc2c1ccc1ccccc12 CHEMBL1315298 IC50 43.0 nM
COc1cc(Nc2nc(-c3nccs3)cs2)cc(OC)c1 CHEMBL5290149 IC50 43.95 nM
O/N=c1\cc(-c2ccc(Cl)cc2)oc2c1ccc1ccccc12 CHEMBL4466582 IC50 44.4 nM
COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1 CHEMBL243664 Ki 45.0 nM
O=c1cc(-c2ccccc2Cl)sc2c1ccc1ccccc12 CHEMBL4446470 IC50 45.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3cccc(Cl)c3)oc12 CHEMBL3422352 IC50 46.0 nM
O=c1cc(-c2ccc3ccccc3c2)oc2c1ccc1ccccc12 CHEMBL3230195 IC50 46.4 nM
Clc1ccccc1-c1csc(-c2csc(Nc3ccc(N4CCOCC4)cc3)n2)n1 CHEMBL5273468 IC50 46.56 nM
c1ccc(-c2csc(-c3csc(Nc4ccc(N5CCOCC5)cc4)n3)n2)nc1 CHEMBL5276009 IC50 47.94 nM
Nc1nc(-c2ccccc2)cc(-c2ccc3ccccc3c2)n1 CHEMBL4563547 IC50 51.8 nM
O=c1cc(-c2cccc(O)c2)oc2c1ccc1ccccc12 CHEMBL1801014 IC50 53.1 nM
O=c1cc(-c2ccccc2)oc2ccc3ccccc3c12 CHEMBL26260 IC50 54.0 nM
COc1cc(-c2oc3cc(O)cc(O)c3c(=O)c2O)ccc1O CHEMBL379064 IC50 56.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(N)n3)oc12 CHEMBL4761904 IC50 56.8 nM
COc1ccc(/C=C/c2ccc(OC)cc2OC)cc1 CHEMBL242396 IC50 57.5 nM
O=C(/C=C/c1cccnc1)c1cc2ccccc2c2ccccc12 CHEMBL4098125 IC50 58.0 nM
COc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1OC CHEMBL4218749 IC50 58.0 nM
COc1c2ccoc2cc2oc(=O)ccc12 CHEMBL24171 Ki 60.0 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCC)cc1O CHEMBL2387742 IC50 60.0 nM
COc1ccc(/C=C/c2cccc(OC)c2OC)c(OC)c1 CHEMBL3220146 IC50 60.3 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccnc3Br)oc12 CHEMBL4754216 IC50 60.7 nM
COc1cc(/C=C/c2cccs2)cc(OC)c1 CHEMBL42428 IC50 61.0 nM
COc1cc(/C=C\c2cccs2)cc(OC)c1 CHEMBL122532 IC50 61.0 nM
CCOc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1OC CHEMBL4205073 IC50 63.0 nM
COc1ccc(-c2cc(=O)c3cc(OC)c4cccc(OC)c4c3[nH]2)cc1 CHEMBL4456952 IC50 64.7 nM
CCOc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1OCC CHEMBL4210137 IC50 65.0 nM
CC(=O)S[C@H]1CC[C@@H](c2cc(=O)c3ccc4ccccc4c3o2)CC1 CHEMBL4470607 IC50 65.0 nM
S=c1cc(-c2ccccc2)oc2c1ccc1ccccc12 CHEMBL4461997 IC50 65.4 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(N)cn3)oc12 CHEMBL4792471 IC50 66.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(O)c(-c3cccc(F)c3)oc12 CHEMBL3422349 IC50 66.9 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(OCc4ccccc4)cc3)oc12 CHEMBL3422343 IC50 67.8 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOCCOC(=O)CN)c(-c3cccc(F)c3)oc12 CHEMBL3422357 IC50 70.24 nM
c1cn(Cc2ccc(Nc3nc(-c4nccs4)cs3)cc2)cn1 CHEMBL5280415 IC50 70.38 nM
COc1ccc(/C=C/c2cc(OC)c(OC)c(OC)c2)c(OC)c1 CHEMBL3220147 IC50 71.0 nM
COc1cccc(-c2cc(=S)c3ccc4ccccc4c3o2)c1 CHEMBL4551672 IC50 72.8 nM
Fc1cccc(Nc2nc(-c3nc(-c4ccncc4)cs3)cs2)c1 CHEMBL5287228 IC50 74.79 nM
O=c1cc([C@H]2CC[C@@H](S)CC2)oc2c1ccc1ccccc12 CHEMBL4441141 IC50 76.2 nM
O=c1c(O)c(-c2ccccc2)oc2cc(O)cc(O)c12 CHEMBL309490 IC50 77.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cncc(O)c3)oc12 CHEMBL4781446 IC50 80.9 nM
O=c1cc(-c2ccccc2F)sc2c1ccc1ccccc12 CHEMBL4546511 IC50 84.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cncc(C(=O)O)c3)oc12 CHEMBL4763388 IC50 85.8 nM
COc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2O)cc1 CHEMBL40919 IC50 88.0 nM
COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1O CHEMBL90568 Ki 89.0 nM
CCOc1cc(C)cc(C)c1C(C)(C)CC(=O)Nc1ccc2c(c1)Oc1cc(NC(=O)N3CCOCC3)ccc1C21Oc2ccccc2C1=O CHEMBL452523 Km 90.0 nM
COc1ccc(/C=C/c2cc(O)cc(O)c2)cc1OC CHEMBL473518 KI 90.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccnc(Cl)c3)oc12 CHEMBL4799305 IC50 91.6 nM
CCOc1cc(/C=C/C(=O)c2ccncc2)cc(OCC)c1OCC CHEMBL4211876 IC50 92.0 nM
c1csc(-c2csc(Nc3ccc4c(c3)OCO4)n2)n1 CHEMBL5278329 IC50 93.0 nM
COc1cc(-c2cc(=O)c3c(O)cc(O)cc3o2)ccc1O CHEMBL214321 IC50 94.7 nM
O/N=c1\cc(-c2cccc(Cl)c2)oc2c1ccc1ccccc12 CHEMBL4458757 IC50 94.9 nM
CCc1sc(-c2csc(Nc3cc(Cl)cc(Cl)c3)n2)nc1-c1ccccc1 CHEMBL5267009 IC50 99.94 nM
N#C[Se]Cc1ccccc1 CHEMBL1806721 IC50 100.0 nM
N#C[Se]Cc1ccccc1C[Se]C#N CHEMBL4099741 IC50 100.0 nM
N#C[Se]Cc1cccc(C[Se]C#N)c1 CHEMBL4075813 IC50 100.0 nM
N#C[Se]Cc1ccc(C[Se]C#N)cc1 CHEMBL113478 IC50 100.0 nM
Cc1sc(-c2csc(Nc3cccc(F)c3)n2)nc1-c1ccncc1 CHEMBL5275310 IC50 105.2 nM
Fc1ccccc1-c1csc(-c2csc(Nc3ccc(N4CCOCC4)cc3)n2)n1 CHEMBL5278091 IC50 109.54 nM
O=c1cc(-c2ccccc2)oc2c3c(cc(O)c12)OCC=C3 CHEMBL2347912 IC50 110.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(O)cc3)oc12 CHEMBL3422345 IC50 113.7 nM
O=C(/C=C/c1cccnc1)c1ccc2ccccc2c1O CHEMBL4559128 IC50 117.1 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc4ccccc4n3)oc12 CHEMBL4742050 IC50 117.6 nM
COc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2O)cc1O CHEMBL226034 IC50 120.0 nM
COc1cc(O)cc(/C=C/c2ccc(O)cc2)c1 CHEMBL498917 Ki 120.0 nM
O=C(/C=C/c1cccnc1)c1ccc2ccc3ccccc3c2c1 CHEMBL4080095 IC50 122.0 nM
C#CCOc1ccccc1-c1csc(-c2csc(Nc3cccc(F)c3)n2)n1 CHEMBL5280421 IC50 125.2 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccnnc3)oc12 CHEMBL4749988 IC50 125.7 nM
O=C1C=C(c2ccccc2)S(=O)(=O)c2c1ccc1ccccc21 CHEMBL4462604 IC50 129.2 nM
C#CCOc1cccc(-c2cc(=O)c3c(O)cccc3o2)c1 CHEMBL2347914 Ki 130.0 nM
Cc1ccc(-c2cc3cc(F)ccc3[nH]2)cc1N CHEMBL5269680 IC50 130.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(N4CCOCC4)c3)oc12 CHEMBL4740535 IC50 132.5 nM
O=c1cc(C2CCCC(S)C2)oc2c1ccc1ccccc12 CHEMBL4573324 IC50 133.5 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccnc3N)oc12 CHEMBL4746672 IC50 137.1 nM
COc1cc(/C=C/c2cc(OC)c(OC)c(OC)c2)cc(OC)c1 CHEMBL43741 IC50 140.0 nM
CCCCN1CCN(c2ccc(S(=O)(=O)Oc3cc(OC)c(OC)c(OC)c3)cc2)C1=O CHEMBL4078072 Ki 140.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc4cc[nH]c4c3)oc12 CHEMBL4746733 IC50 141.9 nM
O=c1cc([C@H]2CC[C@H](S)CC2)oc2c1ccc1ccccc12 CHEMBL4476231 IC50 146.0 nM
CC#Cc1ccc2c(ccc3ccccc32)c1 CHEMBL253346 IC50 150.0 nM
O=c1cc(-c2ccccc2)oc2ccc3c(c12)C=CCO3 CHEMBL2347755 IC50 150.0 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O CHEMBL190461 Ki(app) 150.0 nM
C#Cc1cc2ccc3cccc4ccc(c1)c2c34 CHEMBL3215302 IC50 151.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccnc3O)oc12 CHEMBL4740715 IC50 151.9 nM
CCc1sc(-c2csc(Nc3ccc(N4CCOCC4)cc3)n2)nc1-c1ccncc1 CHEMBL5266551 IC50 152.69 nM
CN1CCN(c2ccc(-c3cc(=O)c4ccc5ccccc5c4o3)cc2)CC1 CHEMBL4470790 IC50 153.4 nM
COc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 CHEMBL291501 Ki 160.0 nM
COc1ccc(OC)c2c(O)c(C(=O)/C=C/c3ccccc3)cc(OC)c12 CHEMBL4454231 IC50 161.3 nM
COc1cc(Cl)cc(-c2cc(=O)c3ccc4ccccc4c3o2)c1 CHEMBL4541619 IC50 163.9 nM
c1csc(-c2csc(Nc3ccc(Cn4cncn4)cc3)n2)n1 CHEMBL5290366 IC50 165.7 nM
Fc1ccc(-c2csc(-c3csc(Nc4ccc(N5CCOCC5)cc4)n3)n2)cc1 CHEMBL5277521 IC50 168.8 nM
Clc1cc(Cl)cc(Nc2nc(-c3nccs3)cs2)c1 CHEMBL5280516 IC50 177.9 nM
COc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1 CHEMBL4214111 IC50 180.0 nM
CCCCCN1CCN(c2ccc(S(=O)(=O)Oc3cccc(I)c3)cc2)C1=O CHEMBL5426962 Ki 190.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOC(=O)[C@@H](N)C(C)C)c(-c3cccc(F)c3)oc12 CHEMBL3422356 IC50 192.0 nM
COc1ccc(-c2cc(=O)c3c(O)c(OC)c(OC)cc3o2)cc1O CHEMBL487402 Ki 210.0 nM
COc1ccc(-c2csc(-c3csc(Nc4cccc(F)c4)n3)n2)cc1OC CHEMBL5277075 IC50 210.2 nM
[N-]=[N+]=NCC1CCC(c2cc(=O)c3ccc4ccccc4c3o2)CC1 CHEMBL4571646 IC50 215.6 nM
CC#Cc1ccc(-c2ccccc2)cc1 CHEMBL1743360 KI 220.0 nM
COc1c(C(=O)/C=C/c2ccccc2)ccc2ccccc12 CHEMBL4468505 IC50 220.5 nM
COc1cc(Nc2nc(-c3nc(-c4ccccc4)cs3)cs2)cc(OC)c1 CHEMBL5289888 IC50 222.4 nM
O=c1cc(-c2ccccc2Cl)oc2c1ccc1ccccc12 CHEMBL175450 IC50 227.9 nM
COc1ccc(/C=C/c2c(OC)cccc2OC)cc1OC CHEMBL3132928 IC50 230.0 nM
CCOc1c(OC)cc(/C=C/C(=O)c2ccncc2)cc1OC CHEMBL4213815 IC50 230.0 nM
CCCCCN1CCN(c2ccc(S(=O)(=O)Oc3cc(OC)cc(OC)c3)cc2)C1=O CHEMBL5432109 Ki 230.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccnc(O)c3)oc12 CHEMBL4740805 IC50 232.0 nM
CCCN1CCN(c2ccc(S(=O)(=O)Oc3cc(OC)c(OC)c(OC)c3)cc2)C1=O CHEMBL4096550 Ki 240.0 nM
O=c1cc(-c2cccc(O)c2)oc2c1ccc1occc12 CHEMBL4763663 IC50 240.0 nM
CCc1sc(-c2csc(Nc3cccc(F)c3)n2)nc1-c1ccccc1 CHEMBL5267964 IC50 246.3 nM
O=C(/C=C/c1ccc[nH]1)c1ccc2ccccc2c1O CHEMBL4566759 IC50 250.0 nM
O=c1c2ccccc2nc2n1CCc1c-2[nH]c2ccccc12 CHEMBL85139 IC50 260.0 nM
O=c1c2ccccc2nc2c3[nH]c4ccccc4c3ccn12 CHEMBL4098122 IC50 260.0 nM
Clc1cccc(Nc2nc(-c3nccs3)cs2)c1 CHEMBL5276078 IC50 261.6 nM
O=c1cc(-c2ccccc2)oc2c3c(ccc12)OCC=C3 CHEMBL2347756 IC50 270.0 nM
COc1cc(OC)c(/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 CHEMBL3132931 IC50 270.0 nM
C#CCOc1ccccc1-c1csc(-c2csc(Nc3cc(OC)cc(OC)c3)n2)n1 CHEMBL5270659 IC50 271.0 nM
Cc1sc(-c2csc(Nc3ccc(N4CCOCC4)cc3)n2)nc1-c1ccncc1 CHEMBL5278741 IC50 276.4 nM
COc1c(C(=O)/C=C(\O)c2ccc3c(c2)OCO3)ccc2occc12 CHEMBL573847 IC50 280.0 nM
COc1c(-c2cc(-c3ccccc3)n(-c3ccc(C#N)cc3)n2)ccc2occc12 CHEMBL4740121 IC50 280.0 nM
Nc1c(C(=O)/C=C/c2ccccc2)ccc2ccccc12 CHEMBL4473797 IC50 285.8 nM
COc1cc(/C=C/C(=O)c2cccnc2)cc(OC)c1OC CHEMBL4079191 IC50 288.0 nM
COc1ccc(/C=C/C(=O)c2cccnc2)c(OC)c1OC CHEMBL2237709 IC50 297.0 nM
CC(C)CN1CCN(c2ccc(S(=O)(=O)Oc3cc(Br)cc(Br)c3)cc2)C1=O CHEMBL5077719 Ki 300.0 nM
Nc1cc(-c2cc3cc(F)ccc3[nH]2)ccc1F CHEMBL5289750 IC50 300.0 nM
O=C(/C=C/c1ccncc1)c1ccc2ccccc2c1O CHEMBL4469707 IC50 300.9 nM
COc1cc(Nc2nc(-c3nc(-c4cccc(OC)c4)cs3)cs2)cc(OC)c1 CHEMBL5282286 IC50 301.3 nM
O=C(CCc1ccccc1)c1ccc2ccccc2c1O CHEMBL4449722 IC50 306.4 nM
Fc1cccc(Nc2nc(-c3nc(-c4ccccn4)cs3)cs2)c1 CHEMBL5280764 IC50 314.3 nM
COc1cccc(-c2csc(-c3csc(Nc4ccc(N5CCOCC5)cc4)n3)n2)c1 CHEMBL5268929 IC50 314.8 nM
Cc1sc(-c2csc(Nc3cc(Cl)cc(Cl)c3)n2)nc1-c1ccccc1 CHEMBL5270417 IC50 315.7 nM
O=c1cc(-c2ccccc2)oc2ccc3c(c12)OCC=C3 CHEMBL2347754 IC50 320.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cccc(O)n3)oc12 CHEMBL4745897 IC50 322.6 nM
COc1cc(Nc2nc(-c3nc(-c4ccccc4Cl)cs3)cs2)cc(OC)c1 CHEMBL5269203 IC50 323.4 nM
O=C(/C=C/c1ccccc1F)c1ccc2ccccc2c1O CHEMBL4581268 IC50 330.0 nM
c1ccc(-c2csc(-c3csc(Nc4ccc(N5CCOCC5)cc4)n3)n2)cc1 CHEMBL5268442 IC50 334.2 nM
COc1cc(Nc2nc(-c3nc(-c4ccccc4F)cs3)cs2)cc(OC)c1 CHEMBL5280088 IC50 347.3 nM
O=C(/C=C/c1cccnc1)c1ccc2ccccc2c1 CHEMBL4063333 IC50 349.0 nM
C#CCOc1cc(O)c2c(=O)cc(-c3ccccc3)oc2c1 CHEMBL2347911 IC50 350.0 nM
COc1ccccc1/C=C/c1ccc(OC)c(OC)c1 CHEMBL3132924 IC50 360.0 nM
O=C(/C=C/c1ccccc1O)c1ccc2ccccc2c1O CHEMBL4476356 IC50 364.7 nM
Fc1ccccc1-c1csc(-c2csc(Nc3cc(Cl)cc(Cl)c3)n2)n1 CHEMBL5283668 IC50 369.7 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 Ki 370.0 nM
COc1ccc(/C=C/C(=O)c2ccncc2)cc1OC CHEMBL4202990 IC50 380.0 nM
Clc1cc(Cl)cc(Nc2nc(-c3nc(-c4cccnc4)cs3)cs2)c1 CHEMBL5275398 IC50 387.2 nM
COc1cc(Nc2nc(-c3nc(-c4ccccc4)c(C)s3)cs2)cc(OC)c1 CHEMBL5272757 IC50 387.8 nM
O=c1cc(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL28 Ki 390.0 nM
CC(C)(O)CCCC1(C)CC(=O)c2cc(O)c(Br)cc2O1 CHEMBL4063209 IC50 390.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(F)cc(NC(=O)CCCCN)c3)oc12 CHEMBL5435493 IC50 396.77 nM
COc1cc(OC)c(/C=C/c2ccc(SC)cc2)c(OC)c1 CHEMBL2071352 IC50 400.0 nM
Cc1cc(Cl)c2c(c1N)C(=O)c1ccccc1C2=O CHEMBL4089401 IC50 400.0 nM
CCCCc1c2c(c(C)c3c1C(=O)OC3)Oc1ccccc1O2 CHEMBL373804 IC50 400.0 nM
O=C(/C=C/c1ccc(Cl)cc1)c1ccc2ccccc2c1O CHEMBL1935214 IC50 401.2 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(F)cc(OCCOCCN)c3)oc12 CHEMBL5418796 IC50 403.53 nM
COc1cccc(Nc2nc(-c3nccs3)cs2)c1 CHEMBL5268347 IC50 414.3 nM
COc1cc(OC)c2nc3n(c(=O)c2c1)CCc1c-3[nH]c2ccccc12 CHEMBL314445 IC50 420.0 nM
Cc1cc2c(ccc3c(=O)cc(-c4ccccc4)oc32)o1 CHEMBL3601433 Ki 430.0 nM
O=C(/C=C/c1cccc(Cl)c1)c1ccc2ccccc2c1O CHEMBL4566283 IC50 434.9 nM
COc1ccc(/C=C/c2ccccc2)cc1OC CHEMBL327223 IC50 440.0 nM
COc1cccc2c(=O)n3c(nc12)-c1[nH]c2ccccc2c1CC3 CHEMBL314132 IC50 450.0 nM
COc1ccc(/C=C/c2cccc(OC)c2OC)cc1OC CHEMBL3132925 IC50 450.0 nM
Cc1cc2c(cc(O)c3c(=O)cc(-c4ccccc4)oc32)o1 CHEMBL3601434 Ki 470.0 nM
O=c1[nH]c(-c2ccc(OCc3ccc(F)cc3F)cc2)nc2ccccc12 CHEMBL4084413 IC50 477.0 nM
COc1cc(Nc2nc(-c3nc(-c4ccc(OC)c(OC)c4)cs3)cs2)cc(OC)c1 CHEMBL5278641 IC50 480.5 nM
Clc1cc(Nc2nc(-c3nccs3)cs2)cc(Cl)c1Cl CHEMBL5266178 IC50 482.3 nM
CCCCN1CCN(c2ccc(S(=O)(=O)Oc3cc(OC)cc(OC)c3)cc2)C1=O CHEMBL4104764 Ki 490.0 nM
O=C(/C=C/c1cccc(F)c1)c1ccc2ccccc2c1O CHEMBL4518018 IC50 499.0 nM
COc1ccc(OC)c(/C=C/c2ccc(OC)c(OC)c2)c1 CHEMBL3132927 IC50 500.0 nM
CC(C)CN1CCN(c2ccc(S(=O)(=O)Oc3cc(Cl)cc(Cl)c3)cc2)C1=O CHEMBL5073496 Ki 500.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(F)cc(NC(=O)CCCCCCN)c3)oc12 CHEMBL5396845 IC50 509.5 nM
O=C(/C=C/c1cccc2ccccc12)c1ccncc1 CHEMBL1568243 IC50 510.0 nM
COc1cc(Nc2nc(-c3nc(-c4ccccc4)c(-c4ccccc4)s3)cs2)cc(OC)c1 CHEMBL5278510 IC50 524.2 nM
[N-]=[N+]=N[C@H]1CC[C@@H](c2cc(=O)c3ccc4ccccc4c3o2)CC1 CHEMBL4444783 IC50 525.0 nM
O=C(/C=C/c1ccccc1Cl)c1ccc2ccccc2c1O CHEMBL1935213 IC50 529.0 nM
COc1ccc(OC)c2c(OC)c(/C=C/C(=O)c3ccc4ccccc4c3O)cc(OC)c12 CHEMBL4445947 IC50 532.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)oc12 CHEMBL3422344 IC50 535.1 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL74415 Ki 541.0 nM
COc1cc(Nc2nc(-c3nc(-c4cccc(C#N)c4)cs3)cs2)cc(OC)c1 CHEMBL5270385 IC50 552.5 nM
COc1ccccc1/C=C/C(=O)c1ccc2ccccc2c1O CHEMBL4514655 IC50 556.6 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(F)cc(NC(=O)COCCN)c3)oc12 CHEMBL5426998 IC50 562.53 nM
COc1cc(/C=C/c2ccc(O)cc2)cc(OC)c1 CHEMBL83527 Ki 570.0 nM
COc1ccccc1/C=C/C(=O)c1ccncc1 CHEMBL4209004 IC50 570.0 nM
COc1c2ccoc2c(OCC=C(C)C)c2oc(=O)ccc12 CHEMBL452751 IC50 580.0 nM
Clc1ccc(Nc2nc(-c3nccs3)cs2)cc1 CHEMBL5289447 IC50 586.4 nM
COc1cccc(/C=C/C(=O)c2ccncc2)c1 CHEMBL4212722 IC50 590.0 nM
CCCCCN1CCN(c2ccc(S(=O)(=O)Oc3cccc(Cl)c3)cc2)C1=O CHEMBL5437198 Ki 600.0 nM
COc1cc(/C=C/c2ccc(OC)cc2F)cc(OC)c1 CHEMBL43740 IC50 610.0 nM
CCc1sc(-c2csc(Nc3cc(OC)cc(OC)c3)n2)nc1-c1ccccc1 CHEMBL5268876 IC50 610.6 nM
COc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2)cc1O CHEMBL124885 Ki 630.0 nM
O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL150 IC50 632.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(F)cc(OCCOCCOCCN)c3)oc12 CHEMBL5426732 IC50 651.7 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL50 Ki 660.0 nM
Cc1sc2[nH]c(CNc3ccc(F)cc3)nc(=O)c2c1C CHEMBL5281041 IC50 700.0 nM
O=C(/C=C/c1ccc2ccccc2c1)c1cccnc1 CHEMBL4059677 IC50 742.0 nM
COc1cc(/C=C/c2ccc(OC)c(OC)c2)cc(OC)c1 CHEMBL44509 IC50 750.0 nM
C#CCOc1ccc(-c2nc3ccccc3c(=O)[nH]2)cc1 CHEMBL4074105 IC50 790.0 nM
COc1ccc2cc(C(=O)/C=C/c3cccnc3)ccc2c1 CHEMBL4092737 IC50 795.0 nM
COc1cc(OC)c(OC)cc1/C=C/c1ccc(SC)cc1 CHEMBL2071351 IC50 800.0 nM
COc1cc(Nc2nc(-c3nc(-c4cccc(F)c4)cs3)cs2)cc(OC)c1 CHEMBL5288164 IC50 819.68 nM
COc1ccc(-c2csc(-c3csc(Nc4cc(OC)cc(OC)c4)n3)n2)cc1 CHEMBL5280700 IC50 823.1 nM
COc1ccc(/C=C/c2cc(OC)cc(OC)c2)cc1 CHEMBL296411 IC50 830.0 nM
COc1ccc2c(=O)n3c(nc2c1)-c1[nH]c2ccccc2c1CC3 CHEMBL312248 IC50 850.0 nM
COc1ccc2nc3n(c(=O)c2c1OC)CCc1c-3[nH]c2ccccc12 CHEMBL86022 IC50 870.0 nM
COc1cc(OC)cc(C(=O)/C=C/c2cccnc2)c1 CHEMBL4093676 IC50 879.0 nM
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL151 Ki 890.0 nM
Clc1cc(Cl)cc(Nc2nc(-c3nc(-c4ccccc4)cs3)cs2)c1 CHEMBL5281938 IC50 895.9 nM
COc1ccc(/C=C/c2ccc(SC)cc2)c(OC)c1OC CHEMBL2071350 IC50 900.0 nM
COc1ccccc1/C=C/C(=O)c1ccc[nH]1 CHEMBL4105559 IC50 900.0 nM
O=C(/C=C/c1ccncc1)c1ccc2ccccc2c1 CHEMBL4082447 IC50 907.0 nM
Clc1cc(Cl)cc(Nc2nc(-c3nc(-c4ccccn4)cs3)cs2)c1 CHEMBL5276124 IC50 915.8 nM
COc1cc(/C=C/c2cc(OC)cc(OC)c2)cc(OC)c1 CHEMBL441035 IC50 920.0 nM
C/C(=C\C(=O)c1cc(O)c(Br)cc1O)CCCC(C)(C)O CHEMBL4092623 IC50 930.0 nM
Fc1ccc(Nc2nc(-c3nccs3)cs2)cc1 CHEMBL5279084 IC50 956.8 nM
O=C(/C=C/c1cccnc1)c1cccc2ccccc12 CHEMBL4071959 IC50 958.0 nM
COc1ccc2c(=O)n3c(nc2c1OC)-c1[nH]c2ccccc2c1CC3 CHEMBL85740 IC50 970.0 nM
COc1cc(/C=C/c2ccc(OC)cc2O)cc(OC)c1 CHEMBL43395 IC50 980.0 nM
COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3cc(F)cc(NC(=O)CCCCCCCCN)c3)oc12 CHEMBL5421843 IC50 989.6 nM
Fc1cccc(Nc2nc(-c3nccs3)cs2)c1 CHEMBL5278948 IC50 993.6 nM
c1csc(-c2csc(Nc3ccc(N4CCOCC4)cc3)n2)n1 CHEMBL5287748 IC50 993.6 nM
CSc1ccc(/C=C/c2ccccc2Cl)cc1 CHEMBL2071353 IC50 1000.0 nM
COc1ccccc1/C=C/c1ccc(SC)cc1 CHEMBL2071343 IC50 1000.0 nM