Clc1cccc(C(c2ccc3[nH]cnc3c2)n2ccnc2)c1 CHEMBL389433 IC50 2.3 nM
C=C1/C(=C\C=C\c2cc(CCCCCC(C)(C)O)cc(CCCCCC(C)(C)O)c2)C[C@@H](O)C[C@@H]1O CHEMBL5182683 EC50 2.96 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL846 EC50 3.02 nM
C=C1/C(=C\C=C(/CCCCCC(C)(C)O)c2cccc(CCCCCC(C)(C)O)c2)C[C@@H](O)C[C@@H]1O CHEMBL5175578 EC50 5.6 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CCS(=N)(=O)c4ccccc4)CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL389014 IC50 6.5 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)C([C@H](C)CC[S+](=N)([O-])c4ccccc4)=CCC23)C[C@@H](O)C[C@@H]1O CHEMBL255088 IC50 7.4 nM
COc1cc(/C=C/c2ccc(C(=O)NCC(c3ccccc3)n3ccnc3)cc2)cc(OC)c1 CHEMBL3329769 Ki 7.8 nM
C[C@H](CC[S+](=N)([O-])c1ccccc1)[C@H]1CC[C@H]2/C(=C/C=C3C[C@@H](O)C[C@H](O)C3)CCC[C@]12C CHEMBL1627206 IC50 9.7 nM
COc1cc(/C=C/c2ccc(C(=O)NCC(c3ccccc3)n3ccnc3)cc2)cc(OC)c1OC CHEMBL3329770 Ki 9.7 nM
COc1cc(/C=C/c2ccc(CCC(OC(=O)n3ccnc3)C(C)(C)C)cc2)cc(OC)c1 CHEMBL3329774 Ki 11.0 nM
CC(C)(C)C(=O)/C(=C/c1ccc(/C=C/c2ccccc2)cc1)n1ccnc1 CHEMBL3329778 Ki 13.0 nM
C(=C/c1cccc2c1ccn2CCCCn1ccnc1)\c1ccccc1 CHEMBL3344394 Ki 14.0 nM
COc1cc(/C=C/c2cccc3c2ccn3CCCCn2ccnc2)cc(OC)c1 CHEMBL3344395 Ki 14.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL253613 IC50 15.0 nM
O=C(NC[C@@H](c1ccccc1)n1ccnc1)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL1170908 IC50 15.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1ccc(/C=C/c2ccc(F)cc2)cc1 CHEMBL3329767 Ki 19.0 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CC4([S+](=N)([O-])c5ccccc5)CC4)CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL1627203 IC50 20.5 nM
C=C1[C@H](O)CC(=C/C=C2\CCC[C@]3(C)[C@@H]([C@H](C)Cn4ccnc4)CC[C@@H]23)C[C@H]1O CHEMBL3360784 Ki 21.0 nM
COc1ccc(/C=C/c2ccc(C(=O)NCC(c3ccccc3)n3ccnc3)cc2)cc1 CHEMBL3329768 Ki 24.0 nM
C(=C/c1cccc2c1ccn2CCCn1ccnc1)\c1ccccc1 CHEMBL3344392 Ki 26.0 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)C([C@H](C)C/C=C/S(=O)(=O)C(C)(C)C)=CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL2105705 IC50 27.0 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)C([C@H](C)/C=C/S(=O)(=O)C(C)(C)C)=CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL4797263 IC50 27.0 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CCS(=O)(=O)c4ccccc4)CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL224719 IC50 28.0 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)CC[S+](=N)([O-])c4ccc(F)cc4)CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL1627207 IC50 28.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1ccc(/C=C/c2ccccc2)cc1 CHEMBL1171494 Ki 28.0 nM
COc1cc(/C=C/c2cccc3c2ccn3CCCn2ccnc2)cc(OC)c1 CHEMBL3344393 Ki 31.0 nM
CC(=O)N1CCN(c2ccc(OCC3COC(Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 CHEMBL157101 Ki 33.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1ccc(CCc2ccc(F)cc2)cc1 CHEMBL3329771 Ki 36.0 nM
C(=C/c1ccc2c(ccn2CCCn2ccnc2)c1)\c1ccccc1 CHEMBL3344396 Ki 37.0 nM
C(=C/c1ccc2c(ccn2CCCCn2ccnc2)c1)\c1ccccc1 CHEMBL3344397 Ki 37.0 nM
C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCOS(=O)(=O)c3ccc(C)cc3)CC[C@@H]12 CHEMBL3360783 Ki 39.0 nM
CC(C)(C)C(=O)C(Cc1ccc(CCc2ccccc2)cc1)n1ccnc1 CHEMBL3329779 Ki 42.0 nM
C=C1[C@H](O)CC(=C/C=C2\CCC[C@]3(C)[C@@H]([C@H](C)CCCNC4CC4)CC[C@@H]23)C[C@H]1O CHEMBL3360785 Ki 42.0 nM
C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CC[S+](=N)([O-])c3ccccc3)CC[C@@H]12 CHEMBL1627204 IC50 75.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 CHEMBL3329772 Ki 91.0 nM
COc1ccc(C(CNC(=O)c2ccc(/C=C/c3ccccc3)cc2)n2ccnc2)cc1 CHEMBL4105510 IC50 110.0 nM
COc1ccc(/C=C/c2ccc(C(=O)NCC(c3ccc(Cl)cc3)n3ccnc3)cc2)cc1OC CHEMBL4080128 IC50 120.0 nM
COc1cc(/C=C/c2ccc(CCC(=O)C(C)(C)C)cc2)cc(OC)c1 CHEMBL3329773 Ki 150.0 nM
O=C(NCC(c1ccc(C(F)(F)F)cc1)n1ccnc1)c1cccc(/C=C/c2ccccc2)c1 CHEMBL4066700 IC50 150.0 nM
O=C(NCC(c1ccc(Cl)cc1)n1ccnc1)c1cccc(/C=C/c2ccccc2)c1 CHEMBL4087998 IC50 160.0 nM
O=C(NCC(c1ccc(C(F)(F)F)cc1)n1ccnc1)c1ccc(/C=C/c2ccccc2)cc1 CHEMBL4103700 IC50 180.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1cccc(/C=C/c2ccccc2)c1 CHEMBL4104362 IC50 190.0 nM
COc1cc(/C=C/c2ccc(CCC(OS(=O)(=O)c3ccc(C)cc3)C(C)(C)C)cc2)cc(OC)c1 CHEMBL3329777 Ki 210.0 nM
O=C(NCC(c1ccc(Cl)cc1)n1ccnc1)c1ccc(/C=C/c2ccccc2)cc1 CHEMBL4087325 IC50 210.0 nM
Cc1ccc(S(=O)(=O)NCCCCn2ccc3c(/C=C/c4ccccc4)cccc32)cc1 CHEMBL3344400 Ki 230.0 nM
CC(=O)N1CCN(c2ccc(OC[C@H]3CO[C@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 CHEMBL75 IC50 300.0 nM
Cc1ccc(C(CNC(=O)c2ccc(/C=C/c3ccccc3)cc2)n2ccnc2)cc1C CHEMBL4076840 IC50 310.0 nM
Cc1ccc(S(=O)(=O)NCCCn2ccc3c(/C=C/c4ccccc4)cccc32)cc1 CHEMBL3344398 Ki 340.0 nM
O=C(NCC(c1ccccc1)n1ccnc1)c1cccc(/C=C/c2ccccc2C(F)(F)F)c1 CHEMBL4060725 IC50 340.0 nM
O=C(NCC(c1ccccc1C(F)(F)F)n1ccnc1)c1ccc(/C=C/c2ccccc2)cc1 CHEMBL4079445 IC50 350.0 nM
COc1cc(/C=C/c2ccc(CCC(OS(C)(=O)=O)C(C)(C)C)cc2)cc(OC)c1 CHEMBL3329776 Ki 380.0 nM
CC(C)(C)C(CCc1ccc(/C=C/c2ccccc2)cc1)OS(C)(=O)=O CHEMBL3329775 Ki 400.0 nM
O=S(OCCCn1ccc2c(/C=C/c3ccccc3)cccc21)c1ccccc1 CHEMBL3344402 Ki 540.0 nM
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@@H](C)/C=C/[S+](=N)([O-])c4ccccc4)CC[C@@H]23)C[C@@H](O)C[C@@H]1O CHEMBL1627205 IC50 549.0 nM
Cc1ccc(S(=O)(=O)OCCCn2ccc3c(/C=C/c4ccccc4)cccc32)cc1 CHEMBL3344403 Ki 640.0 nM
COc1cc(/C=C/c2cccc3c2ccn3CCCNS(=O)(=O)c2ccc(C)cc2)cc(OC)c1 CHEMBL3344399 Ki 730.0 nM
COc1cc(/C=C/c2cccc3c2ccn3CCCCNS(=O)(=O)c2ccc(C)cc2)cc(OC)c1 CHEMBL3344401 Ki 740.0 nM
COc1ccc2c(c1)CCC(Cc1ccccc1C)C2=O CHEMBL363039 IC50 900.0 nM
COc1ccc2c(c1)CC/C(=C\c1cc(C(F)(F)F)ccc1C(F)(F)F)C2=O CHEMBL365510 IC50 900.0 nM