CC1(C)CCC(C)(C)c2cc(C3(c4ccc(CCC(=O)O)cc4)OCCO3)ccc21 CHEMBL3787627 Activity 0.27 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1 CHEMBL1831092 IC50 0.3 nM
CCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831083 IC50 0.35 nM
CC1(C)CCC(C)(C)c2cc(C3(c4ccc(/C=C/C(=O)O)cc4)OCCO3)ccc21 CHEMBL3786581 Activity 1.09 nM
CC[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1)N(C)C CHEMBL208443 IC50 1.3 nM
CCN(CC)[C@H](C)[C@@H](c1ccc2cc(OCC3(C(=O)O)CCCC3)ccc2c1)n1ccnc1 CHEMBL205862 IC50 1.4 nM
CC(C)N(C)[C@H](C)[C@@H](c1ccc2cc(OCC3(C(=O)O)CCCC3)ccc2c1)n1ccnc1 CHEMBL207304 IC50 1.6 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1n1ccnc1 CHEMBL57765 IC50 2.4 nM
CC(C)N(C)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 CHEMBL207486 IC50 3.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1766005 IC50 3.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc3cc(O)ccc3c2)cc1)n1ccnc1 CHEMBL1766007 IC50 3.0 nM
CC(C(c1ccc2cc(OCc3ccc(C(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C CHEMBL368448 IC50 3.3 nM
CC(C(c1ccc2cc(OCc3cccc(C(=O)O)c3)ccc2c1)n1ccnc1)N(C)C CHEMBL426789 IC50 3.5 nM
CCC(CC)[C@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 CHEMBL224305 IC50 4.0 nM
CCN(C)[C@H](C)[C@@H](c1ccc2cc(OCC3(C(=O)O)CCCC3)ccc2c1)n1ccnc1 CHEMBL207942 IC50 4.2 nM
CCN(CC)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 CHEMBL208155 IC50 5.0 nM
CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 CHEMBL459505 IC50 5.1 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)n2ccnc2)C(C)(C)CCC1n1ccnc1 CHEMBL223072 IC50 5.2 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1ccnc1 CHEMBL2146987 IC50 5.7 nM
CC(C(c1ccc2cc(OCc3ccc(C#N)cc3)ccc2c1)n1ccnc1)N(C)C CHEMBL359627 IC50 6.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2cccc3ccccc23)cc1)n1ccnc1 CHEMBL1766003 IC50 6.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc3c(c2)OCO3)cc1)n1cncn1 CHEMBL2147090 IC50 6.7 nM
COC(=O)c1cccc(COc2ccc3cc(C(C(C)N(C)C)n4ccnc4)ccc3c2)c1 CHEMBL181309 IC50 7.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC3(C(=O)O)CCCC3)ccc2c1)n1ccnc1)N(C)C CHEMBL377177 IC50 7.3 nM
CC(C(c1ccc2cc(OCc3ccc(OCC(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C CHEMBL179550 IC50 8.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc3c(c2)OCO3)cc1)n1ccnc1 CHEMBL1766001 IC50 8.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc3cc(OC)ccc3c2)cc1)n1ccnc1 CHEMBL1766006 IC50 8.0 nM
CCN(C)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 CHEMBL210780 IC50 9.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(C(F)(F)F)cc2)cc1)n1ccnc1 CHEMBL2146981 IC50 9.4 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 CHEMBL1766000 IC50 10.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 CHEMBL1766008 IC50 10.0 nM
C[C@H]([C@@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C CHEMBL517438 IC50 10.0 nM
CC(C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1)N(C)C CHEMBL3617993 IC50 10.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC3(C(=O)O)CCCCC3)ccc2c1)n1ccnc1)N(C)C CHEMBL207638 IC50 11.2 nM
CNC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831088 IC50 12.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1 CHEMBL2205775 IC50 13.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2cc(C)c(OC)c(C)c2)cc1)n1ccnc1 CHEMBL2146986 IC50 14.0 nM
CC(C(c1ccc2cc(OCc3cccc(C(=O)N(C)C)c3)ccc2c1)n1ccnc1)N(C)C CHEMBL360072 IC50 14.4 nM
COC(=O)c1ccc(COc2ccc3cc(C(C(C)N(C)C)n4ccnc4)ccc3c2)cc1 CHEMBL178474 IC50 16.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(C)cc2)cc1)n1ccnc1 CHEMBL2146980 IC50 16.0 nM
COC(=O)COc1ccc(COc2ccc3cc(C(C(C)N(C)C)n4ccnc4)ccc3c2)cc1 CHEMBL362412 IC50 19.0 nM
CC(C(c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1)N(C)C CHEMBL360771 IC50 20.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1)N(C)C CHEMBL208154 IC50 20.0 nM
CC(C(c1ccc2cc(OCC(C)(C)C)ccc2c1)n1ccnc1)N(C)C CHEMBL180805 IC50 21.4 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1n1ccnc1 CHEMBL190837 IC50 24.0 nM
CC(C(c1ccc2cc(OCc3ccc(CC(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C CHEMBL180348 IC50 25.0 nM
CN(C)C(C)(C)[C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 CHEMBL382574 IC50 26.0 nM
COC(=O)[C@H](C)[C@H](c1ccc(Nc2ccccc2)cc1)n1ccnc1 CHEMBL1766011 IC50 26.0 nM
CC(C(c1ccc2cc(OCc3ccc(OC(C)(C)C)cc3)ccc2c1)n1ccnc1)N(C)C CHEMBL181385 IC50 34.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1)N1CCOCC1 CHEMBL208158 IC50 34.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC3(C(=O)O)CC3)ccc2c1)n1ccnc1)N(C)C CHEMBL206884 IC50 34.7 nM
CC(C(c1ccc2cc(OCC(C)(C)C(=O)N(C)C)ccc2c1)n1ccnc1)N(C)C CHEMBL367357 IC50 35.0 nM
CNC(=O)c1cccc(COc2ccc3cc(C(C(C)N(C)C)n4ccnc4)ccc3c2)c1 CHEMBL182438 IC50 37.0 nM
CCC(CC)(COc1ccc2cc([C@H]([C@@H](C)N(C)C)n3ccnc3)ccc2c1)C(=O)O CHEMBL377286 IC50 37.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC3(C(=O)O)CCC3)ccc2c1)n1ccnc1)N(C)C CHEMBL207345 IC50 40.0 nM
COC(=O)/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C(n2ccnc2)CCC1(C)C CHEMBL224828 IC50 40.0 nM
COC(=O)[C@@H](C)[C@H](c1ccc(Nc2ccccc2)cc1)n1ccnc1 CHEMBL1766010 IC50 40.0 nM
COc1ccc2cc(Nc3ccc(C(n4ccnc4)C(C)(C)CO)cc3)ccc2c1 CHEMBL1831091 IC50 40.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2cc(OC)c(OC)c(OC)c2)cc1)n1ccnc1 CHEMBL2146985 IC50 45.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC3(C(=O)O)CCOCC3)ccc2c1)n1ccnc1)N(C)C CHEMBL378132 IC50 46.7 nM
CC(C(c1ccc2cc(OCC(C)(C)C(N)=O)ccc2c1)n1ccnc1)N(C)C CHEMBL362489 IC50 47.0 nM
CC(C(c1ccc2cc(OCc3cccc(C(N)=O)c3)ccc2c1)n1ccnc1)N(C)C CHEMBL360148 IC50 48.0 nM
CC(C(c1ccc2cc(OCc3ccccc3)ccc2c1)n1ccnc1)N(C)C CHEMBL180856 IC50 50.0 nM
COC(=O)[C@H](C)[C@H](c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1766013 IC50 50.0 nM
CC(C)(C(N)=O)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1828655 IC50 50.0 nM
CNC(=O)C(C)(C)COc1ccc2cc(C(C(C)N(C)C)n3ccnc3)ccc2c1 CHEMBL180829 IC50 54.0 nM
CCCCN(C)[C@H](C)[C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 CHEMBL205280 IC50 60.0 nM
CC1(C)CCC(C)(C)c2cc(C3(c4ccc5cc(C(=O)O)ccc5c4)SCCS3)ccc21 CHEMBL3786184 IC50 60.0 nM
CN(C)C(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831090 IC50 75.0 nM
CC(C(c1ccc2cc(OCc3ccc([N+](=O)[O-])cc3)ccc2c1)n1ccnc1)N(C)C CHEMBL180592 IC50 77.0 nM
CC(C)(C(=O)O)C(c1ccc(Nc2ccc(C(=O)O)cc2)cc1)n1cncn1 CHEMBL2205778 IC50 85.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1C CHEMBL2147091 IC50 90.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(C(C)=O)cc2)cc1)n1cncn1 CHEMBL2205776 IC50 95.0 nM
COC(=O)Cc1ccc(COc2ccc3cc(C(C(C)N(C)C)n4ccnc4)ccc3c2)cc1 CHEMBL179825 IC50 100.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1 CHEMBL1766009 IC50 100.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc([N+](=O)[O-])cc2)cc1)n1ccnc1 CHEMBL2146984 IC50 100.0 nM
CC1(C)CCC(C)(C)c2cc(C3(c4ccc5cc(C(=O)O)ccc5c4)OCCO3)ccc21 CHEMBL3786620 IC50 110.0 nM
CC1(C)CCC(C)(C)c2cc(C3(c4ccc(CCC(=O)O)cc4)SCCS3)ccc21 CHEMBL3787323 Activity 113.0 nM
CC(C)NC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831089 IC50 120.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1)N(C)C1CCCCC1 CHEMBL207411 IC50 125.0 nM
CCOc1ccc2ccccc2c1Nc1ccc(C(n2ccnc2)C(C)(C)C(=O)OC)cc1 CHEMBL1766004 IC50 125.0 nM
COC(=O)[C@@H](C)[C@H](c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1766012 IC50 140.0 nM
CCCCCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831085 IC50 140.0 nM
CCCCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831084 IC50 200.0 nM
CNC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 CHEMBL2205779 IC50 200.0 nM
COC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(-c2ccccc2)c1Cl CHEMBL3617983 IC50 220.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(-c3ccccc3)cc2)cc1)n1ccnc1 CHEMBL1766002 IC50 250.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(F)cc2)cc1)n1ccnc1 CHEMBL2146978 IC50 250.0 nM
CCNC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 CHEMBL2205780 IC50 250.0 nM
CC(C)OC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831086 IC50 290.0 nM
CC(C)(C(=O)O)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831082 IC50 300.0 nM
CC(C(c1ccc2cc(OCC(=O)O)ccc2c1)n1ccnc1)N(C)C CHEMBL178873 IC50 335.0 nM
CNC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1 CHEMBL1831094 IC50 350.0 nM
COC(=O)C(Cn1ccnc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL3617978 IC50 370.0 nM
CC(C)(C(=O)OCc1ccccc1)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 CHEMBL1831087 IC50 400.0 nM
CN(C)C[C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 CHEMBL204684 IC50 403.0 nM
COC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 CHEMBL3617988 IC50 410.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Cl)cc2)cc1)n1ccnc1 CHEMBL2146979 IC50 450.0 nM
Cc1nn(-c2ccccc2)c(Cl)c1C(=O)NC(Cn1ccnc1)C(=O)OC(C)C CHEMBL3617986 IC50 460.0 nM
c1ccc(C(c2ccc(Nc3ccc4ccccc4c3)cc2)n2ccnc2)cc1 CHEMBL518482 IC50 500.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1cncn1 CHEMBL2147089 IC50 500.0 nM
Clc1cccc(C(c2ccc3[nH]cnc3c2)n2ccnc2)c1 CHEMBL389433 IC50 540.0 nM
CC(C)OC(=O)C(Cn1ccnc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL3617981 IC50 540.0 nM
C[C@H]([C@@H](c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1)N1CCCC1 CHEMBL210569 IC50 583.0 nM
CCOC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(-c2ccccc2)c1Cl CHEMBL3617984 IC50 600.0 nM
CCCOC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(-c2ccccc2)c1Cl CHEMBL3617985 IC50 620.0 nM
CC(C)OC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 CHEMBL3617991 IC50 630.0 nM
CCOC(=O)C(Cn1ccnc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL3617979 IC50 650.0 nM
COC(=O)/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)[C@H](n2ccnc2)CCC1(C)C CHEMBL225621 IC50 680.0 nM
COC(=O)C(C)(C)C(c1ccc(Nc2ccc(OC)cc2)cc1)n1ccnc1 CHEMBL2146982 IC50 700.0 nM
CCOC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 CHEMBL3617989 IC50 740.0 nM
CCCOC(=O)C(Cn1ccnc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL3617980 IC50 790.0 nM
CCCOC(=O)C(Cn1ccnc1)NC(=O)c1nc2ccccc2s1 CHEMBL3617990 IC50 840.0 nM
c1ccc(C(c2ccc(Nc3nc4ccccc4o3)cc2)n2ccnc2)cc1 CHEMBL518642 IC50 900.0 nM
CC(C)COC(=O)C(Cn1ccnc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL3617982 IC50 970.0 nM
c1ccc(C(c2ccc(Nc3ccc4c(c3)CCC4)cc2)n2ccnc2)cc1 CHEMBL517904 IC50 1000.0 nM
CNC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1 CHEMBL2205783 IC50 1000.0 nM
CNC(=O)C(C)(C)C(c1ccc(Nc2ccc(Cl)cc2)cc1)n1ccnc1 CHEMBL2205782 IC50 1000.0 nM