O=Cc1cn(-c2nc(-c3cc4c(ccc5ccccc54)oc3=O)cs2)nc1-c1ccccc1 CHEMBL3740883 Ki 0.057 nM
Cc1ccc(-c2nn(-c3nc(-c4cc5cc(Br)ccc5oc4=O)cs3)cc2C=O)cc1 CHEMBL3740902 Ki 1.54 nM
Cc1ccc(-c2nn(-c3nc(-c4cc5cc(Br)cc(Br)c5oc4=O)cs3)cc2C=O)cc1 CHEMBL3741757 Ki 1.73 nM
COc1cccc2cc(-c3csc(-n4cc(C=O)c(-c5ccc(C)cc5)n4)n3)c(=O)oc12 CHEMBL3739596 Ki 1.93 nM
Cc1ccc(-c2nn(-c3nc(-c4cc5cc(Cl)cc(Cl)c5oc4=O)cs3)cc2C=O)cc1 CHEMBL3742224 Ki 2.57 nM
O=Cc1cn(-c2nc(-c3cc4cc(Cl)ccc4oc3=O)cs2)nc1-c1ccccc1 CHEMBL3742383 Ki 2.58 nM
O=Cc1cn(-c2nc(-c3cc4cc(Cl)cc(Cl)c4oc3=O)cs2)nc1-c1ccc(Cl)cc1 CHEMBL3741819 Ki 2.7 nM
O=Cc1cn(-c2nc(-c3cc4cc(Cl)cc(Cl)c4oc3=O)cs2)nc1-c1ccccc1 CHEMBL3740871 Ki 3.07 nM
COc1cccc2cc(-c3csc(-n4cc(C=O)c(-c5ccc(Cl)cc5)n4)n3)c(=O)oc12 CHEMBL3740860 Ki 3.27 nM
O=Cc1cn(-c2nc(-c3cc4cc(Br)cc(Br)c4oc3=O)cs2)nc1-c1ccccc1 CHEMBL3740335 Ki 3.41 nM
O=Cc1cn(-c2nc(-c3cc4cc(Br)ccc4oc3=O)cs2)nc1-c1ccccc1 CHEMBL3742302 Ki 6.02 nM
NCc1cc2ccccc2s1 CHEMBL1770735 Ki 10.0 nM
C#CCOc1cccc2oc(=O)ccc12 CHEMBL5289073 Ki 10.0 nM
Cc1ccc(-c2nn(-c3nc(-c4cc5ccccc5oc4=O)cs3)cc2C=O)cc1 CHEMBL3740529 Ki 10.97 nM
O=Cc1cn(-c2nc(-c3cc4ccccc4oc3=O)cs2)nc1-c1ccccc1 CHEMBL3739579 Ki 12.96 nM
O=Cc1cn(-c2nc(-c3cc4cc(Br)ccc4oc3=O)cs2)nc1-c1ccc(Cl)cc1 CHEMBL3739672 Ki 13.2 nM
O=Cc1cn(-c2nc(-c3cc4cc(Cl)ccc4oc3=O)cs2)nc1-c1ccc(Cl)cc1 CHEMBL3740695 Ki 16.62 nM
CCc1ccncc1-c1ccc(CN)s1 CHEMBL4161819 IC50 17.0 nM
NCc1ccc(-c2cccnc2)s1 CHEMBL359657 Ki 20.0 nM
CCC1CCC(c2cccnc2)O1 CHEMBL3640770 IC50 20.0 nM
C=CCOc1cccc2oc(=O)ccc12 CHEMBL450963 Ki 30.0 nM
NCc1ccc(-c2cccnc2)o1 CHEMBL178090 Ki 40.0 nM
NCC#Cc1cccnc1 CHEMBL360541 Ki 40.0 nM
CNCC#Cc1cccnc1 CHEMBL149808 Ki 40.0 nM
CN(C)CC#Cc1cccnc1 CHEMBL180270 Ki 40.0 nM
CCCc1ccncc1-c1ccc(CN)s1 CHEMBL4165249 IC50 42.0 nM
O=Cc1csc2ccccc12 CHEMBL596015 IC50 50.0 nM
O=Cc1ccc2occc2c1 CHEMBL3358215 IC50 50.0 nM
COc1cccc2oc(=O)ccc12 CHEMBL502746 Ki 50.0 nM
CCc1ccncc1-c1ccc(CN)o1 CHEMBL4173133 IC50 51.0 nM
Cc1ccncc1C#CCN CHEMBL4173088 IC50 55.0 nM
O=Cc1cc2ccncc2s1 CHEMBL3358193 Ki 60.0 nM
O=Cc1ccc2[nH]ccc2c1 CHEMBL3358223 Ki 70.0 nM
O=Cc1cc2cnccc2s1 CHEMBL3358192 Ki 70.0 nM
NCc1ccc(-c2cnccc2-c2ccoc2)s1 CHEMBL4160749 IC50 76.0 nM
N[C@@H]1C[C@H]1c1ccccc1 CHEMBL3989843 IC50 80.0 nM
N[C@@H]1C[C@H]1c1ccccc1 CHEMBL1179 IC50 80.0 nM
CCOc1cccc2oc(=O)ccc12 CHEMBL448936 Ki 80.0 nM
NCc1csc2ccc(Cl)cc12 CHEMBL3358194 Ki 90.0 nM
COc1c2occc2cc2ccc(=O)oc12 CHEMBL416 Ki 90.0 nM
Cc1ccsc1-c1cccnc1 CHEMBL179669 Ki 100.0 nM
N#Cc1ccc2occc2c1 CHEMBL3358216 Ki 100.0 nM
NCc1ccc(-c2cnccc2-c2ccoc2)o1 CHEMBL4169324 IC50 110.0 nM
Cn1cnc(-c2cccnc2)c1 CHEMBL360999 Ki 130.0 nM
C[n+]1c[nH]cc1-c1cccnc1 CHEMBL179399 Ki 130.0 nM
O=Cc1cc2ccccc2s1 CHEMBL3358202 Ki(app) 130.0 nM
NCC#Cc1cnccc1-c1ccccc1 CHEMBL4164113 IC50 130.0 nM
CCCc1ccncc1-c1ccc(CN)o1 CHEMBL4169721 IC50 140.0 nM
Clc1ccc(Cn2ccnc2)cc1 CHEMBL441367 IC50 160.0 nM
NCC#Cc1cccnc1 CHEMBL4171558 IC50 160.0 nM
NCc1ccc(-c2cnccc2-c2ccco2)s1 CHEMBL4168669 IC50 160.0 nM
Cc1cncc(-c2cscc2C)c1 CHEMBL362062 Ki 170.0 nM
Cc1cn(-c2cccnc2)cn1 CHEMBL178781 Ki 170.0 nM
Cc1cncc(-c2ccsc2)c1 CHEMBL3640760 Ki 170.0 nM
CNCc1ccc(-c2cccnc2)s1 CHEMBL369285 Ki 180.0 nM
NCc1csc2ccccc12 CHEMBL1922273 IC50 200.0 nM
NCc1csc2ccc(Br)cc12 CHEMBL3358196 Ki 200.0 nM
COc1ccc2oc(=O)ccc2c1 CHEMBL496547 IC50 200.0 nM
Cc1ccsc1-c1ccc(F)nc1 CHEMBL179621 Ki 210.0 nM
c1cncc(-c2ccsc2)c1 CHEMBL361153 Ki 220.0 nM
Cc1ccncc1-c1ccc(CN)s1 CHEMBL4176100 IC50 220.0 nM
c1ccc(Cn2cnc(-c3cccnc3)c2)cc1 CHEMBL178780 Ki 230.0 nM
O/N=C/c1ccc(-c2cccnc2)s1 CHEMBL178534 Ki 240.0 nM
Cc1nccn1-c1cccnc1 CHEMBL368883 Ki 250.0 nM
Cc1cscc1-c1cccnc1 CHEMBL179704 Ki 250.0 nM
c1cncc(-c2c[nH]cn2)c1 CHEMBL178516 Ki 250.0 nM
CNCc1ccc(-c2cccnc2)o1 CHEMBL178938 Ki 280.0 nM
NCc1ccc(-c2cnccc2-c2ccco2)o1 CHEMBL4161400 IC50 290.0 nM
NCc1cc(-c2cccnc2)n[nH]1 CHEMBL385008 Ki 300.0 nM
NCc1ccc(-c2cnccc2-c2ccncc2)o1 CHEMBL4176506 IC50 300.0 nM
NCC1CCC(c2cccnc2)O1 CHEMBL3640764 IC50 330.0 nM
NCc1ccc(-c2cnccc2-c2ccncc2)s1 CHEMBL4172017 IC50 330.0 nM
NC[C@@H]1CC[C@@H](c2cccnc2)O1 CHEMBL4443442 IC50 330.0 nM
c1cncc(-n2ccnc2)c1 CHEMBL179477 IC50 360.0 nM
BrCC1CCC(c2cccnc2)O1 CHEMBL3640765 IC50 360.0 nM
NCc1ccc(-c2cnccc2-c2cccnc2)o1 CHEMBL4165895 IC50 380.0 nM
Cc1ccncc1-c1ccc(CN)o1 CHEMBL4172417 IC50 390.0 nM
NCc1cc(-c2cccnc2)no1 CHEMBL217125 Ki 400.0 nM
O=Cc1cc2cccnc2s1 CHEMBL3358207 IC50 400.0 nM
NCc1ccc(-c2cnccc2-c2ccccc2)o1 CHEMBL4159065 IC50 400.0 nM
NCc1ccc(-c2cnccc2-c2ccccc2)s1 CHEMBL4175869 IC50 410.0 nM
CCCc1ccncc1C#CCN CHEMBL4171984 IC50 440.0 nM
NCc1ccc(-c2cnccc2-c2cccnc2)s1 CHEMBL4164142 IC50 460.0 nM
CN(C)Cc1cc2cnccc2s1 CHEMBL3358199 Ki 500.0 nM
CNCc1cc2ccccc2s1 CHEMBL3358195 IC50 500.0 nM
O=Cc1csc2ccc(Br)cc12 CHEMBL3358204 IC50 500.0 nM
CCn1cnc(-c2cccnc2)c1 CHEMBL361364 Ki 520.0 nM
CCCOc1cccc2oc(=O)ccc12 CHEMBL451623 Ki 540.0 nM
Brc1ccc2ccccc2c1 CHEMBL192643 pIC50 549.54 nM
COc1ccncc1-c1ccc(CN)s1 CHEMBL4172462 IC50 550.0 nM
NCC#Cc1cnccc1-c1ccco1 CHEMBL4163694 IC50 560.0 nM
CNc1ccc(-c2cccnc2)s1 CHEMBL179529 Ki 590.0 nM
NCC#Cc1cnccc1-c1cccnc1 CHEMBL4170930 IC50 590.0 nM
Nc1ccc(-c2cccnc2)s1 CHEMBL3640762 Ki 590.0 nM
NCc1ccc(-c2ccccc2)s1 CHEMBL215134 Ki 600.0 nM
NCc1ccc(-c2ccccc2)o1 CHEMBL214859 Ki 600.0 nM
O=c1ccc2cc3ccoc3cc2o1 CHEMBL164660 KI 600.0 nM
NCc1ccc2sccc2c1 CHEMBL1922274 IC50 600.0 nM
Fc1ccc2ccccc2c1 CHEMBL191864 pIC50 669.88 nM
NCC#Cc1cnccc1-c1ccoc1 CHEMBL4174365 IC50 670.0 nM
Cn1ccc2cc(C=O)ccc21 CHEMBL3358224 IC50 680.0 nM
CN(C)c1ccc(C=O)cc1 CHEMBL3188333 Kd 680.0 nM
O/N=C/c1ccc(-c2cccnc2)o1 CHEMBL178547 Ki 710.0 nM
CC/C(=C(/c1ccc(O)cc1)c1ccc(OCCN)cc1)c1ccc(O)cc1 CHEMBL3422028 Ki 710.0 nM
O=c1ccc2ccccc2o1 CHEMBL6466 Km 740.0 nM
O=Cc1ccc(-c2cccnc2)s1 CHEMBL179398 Ki 790.0 nM
CSCc1ccc(-c2cccnc2)o1 CHEMBL214990 Ki 800.0 nM
CC(=O)SCc1ccc(-c2cccnc2)o1 CHEMBL386124 Ki 800.0 nM
CNCc1cc2cccnc2s1 CHEMBL3358201 Ki 800.0 nM
CCc1ccncc1C#CCN CHEMBL4175429 IC50 830.0 nM
Cc1coc2c1CCC(C)C2 CHEMBL1522900 KI 840.0 nM
O=Cc1ccc2sccc2c1 CHEMBL3358197 IC50 900.0 nM
Fc1ccc(-c2ccsc2)cn1 CHEMBL179005 Ki 970.0 nM
NCc1cc2cnccc2s1 CHEMBL3358198 IC50 1000.0 nM
COc1ccncc1-c1ccc(CN)o1 CHEMBL4162449 IC50 1000.0 nM
CCCCCc1cc(O)c2c(c1)OC(C)(C)c1ccc(C)cc1-2 CHEMBL74415 Ki 1000.0 nM