Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL91 IC50 0.02 nM
Nc1nc(S)nc(O)c1/N=N\c1c(Br)cc(S(N)(=O)=O)cc1Br CHEMBL1402106 Potency 1.0 nM
C=C(C)C(O)C(CC/C=C(\C)C(=O)OCC)OC CHEMBL1552243 Potency 1.0 nM
C[N+](C)(C)CC(=O)N/N=C/c1ccncc1 CHEMBL1371957 Potency 1.0 nM
COC(=O)C1C(c2ccccc2)C2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c1ccc(OC)cc1 CHEMBL1565567 Potency 1.0 nM
C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL1338347 Potency 1.0 nM
COC(=O)NC(CC(C)=O)c1ccc(F)cc1 CHEMBL1534735 Potency 1.0 nM
CN1CCN(CC(=O)Nc2cccc3ccccc23)CC1 CHEMBL1328802 Potency 1.0 nM
CC1CCC2C(=O)OC(COc3ccc(C(C)(C)C)cc3)CN2C1c1ccc(Br)cc1 CHEMBL1370938 Potency 1.0 nM
O=[N+]([O-])c1cccc2c(Br)n[nH]c12 CHEMBL479014 Potency 1.0 nM
c1ccc(C2CC2)c(OCC2=NCCN2)c1 CHEMBL13852 Potency 1.3 nM
CCNc1nc(NCC)nc(N(C)N)n1 CHEMBL1340517 AC50 1.413 nM
CCC(=O)OCN1C(=O)C=CC1=O CHEMBL1374426 AC50 1.995 nM
O=C(O)C(=O)Cc1ccc2c(c1)OCO2 CHEMBL1371217 Potency 2.0 nM
CCCCCCCCCCCCCCCCOC[C@@H](COCC(F)(F)F)OP(=O)([O-])OCO CHEMBL1515310 Potency 2.0 nM
Cc1ccc(S(=O)(=O)N2CCC(C(=O)O)(c3ccccc3)CC2)cc1 CHEMBL1489668 Potency 2.0 nM
O=C(O)CSSCC(=O)O CHEMBL1611974 Potency 2.0 nM
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O CHEMBL780 Potency 2.5 nM
CO[C@H]1COC(=O)C/C=C\[C@@H](C)[C@H](OC)COC(=O)CCC[C@@H]1C CHEMBL1530445 Potency 2.5 nM
CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]3CCCC[C@H]3N)nc21 CHEMBL1532768 Potency 2.5 nM
Oc1ccc(/C=C\c2cc(O)cc(O)c2)cc1 CHEMBL87333 Potency 2.5 nM
Clc1ccc(CC[C@H](Cn2ccnc2)Sc2c(Cl)cccc2Cl)cc1 CHEMBL1317950 Potency 2.5 nM
CO[C@@H]1COC(=O)CCC[C@@H](C)[C@H](OC)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C\[C@H]1C CHEMBL1514398 Potency 2.5 nM
NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1 CHEMBL1256392 Potency 2.5 nM
COc1cc(C[C@H]2C(=O)OC[C@@H]2Cc2ccc(OC)c(OC)c2)ccc1O CHEMBL435734 Potency 2.5 nM
CC1=C/C(=C(/c2ccc(O)c(C)c2)c2ccccc2C(=O)O)C=CC1=O CHEMBL1437054 AC50 3.162 nM
c1cncc(CNc2ncnc3ccc(-c4cccnc4)cc23)c1 CHEMBL1355644 AC50 3.162 nM
OC[C@@H]1O[C@@H](O)[C@H](/N=C\c2ccc3c(c2)OCO3)[C@@H](O)[C@@H]1O CHEMBL1474703 Potency 3.2 nM
FC(F)(F)c1nnc(-c2ccccc2)nc1Sc1ccccc1 CHEMBL1541405 AC50 3.548 nM
CC1(C)[C@@H]2CC[C@]1(C)[C@@H](OC(=O)/C=C\c1ccccc1)C2 CHEMBL1397334 AC50 3.981 nM
Fc1ccc(C(OCCCc2c[nH]cn2)c2ccc(F)cc2)cc1 CHEMBL1179104 AC50 3.981 nM
CCC/C=C/C1C(=O)C2OC2C2(OCC(CC)(CC)CO2)C1CO CHEMBL1525438 Potency 4.0 nM
O=C(NC1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1)c1cccnc1 CHEMBL4593464 IC50 4.6 nM
CC(C)(C)c1ccc(OCC(=O)O)c(Cl)c1 CHEMBL1487450 Potency 5.0 nM
COc1ccc(O[C@H]2C=C[C@@H](c3ccccc3)O[C@H]2COC(=O)CC/C(C)=N\OC[C@@H](O)[C@H]2O[C@H]3OC(C)(C)O[C@H]3[C@@H]2O)cc1 CHEMBL1329968 Potency 5.0 nM
COc1ccc(NC(=O)CC#N)cc1OC CHEMBL1477447 AC50 5.012 nM
Cn1c(=O)c(C(=O)c2nn[nH]n2)c(O)c2ccc(Cl)cc21 CHEMBL1735517 AC50 5.012 nM
Cc1ccc(OCC(=O)NNC(=O)CCC(=O)NCc2ccccc2)cc1 CHEMBL1439658 AC50 5.623 nM
Cc1ccc(C)c(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc23)c1 CHEMBL1722019 AC50 5.623 nM
CCCNC(=O)Cn1cnc2sc(C(=O)Nc3ccc4c(c3)OCO4)c(C)c2c1=O CHEMBL1611188 AC50 5.623 nM
NC(=O)/C(=N\O)c1ccccc1 CHEMBL3211369 AC50 5.623 nM
Cc1ccc(C2C(C(=O)c3sc(C)nc3C)=C(O)C(=O)N2CCN2CCOCC2)o1 CHEMBL1466584 AC50 5.623 nM
CCn1c(O)c(C(c2ccccn2)c2c(O)n(CC)c(=S)[nH]c2=O)c(=O)[nH]c1=S CHEMBL1558867 AC50 5.623 nM
COc1cc(N2CCOCC2)ncn1 CHEMBL1706736 AC50 5.623 nM
CCc1ccc(C(CC(=O)c2ccc(Cl)cc2)C(=O)O)cc1 CHEMBL1344162 AC50 5.623 nM
O=[N+]([O-])c1cccnc1N1CCCCC1 CHEMBL1550234 AC50 5.623 nM
CC(C)OC(=O)C(C#N)c1nc2ccccc2nc1N1CCN(Cc2ccccc2)CC1 CHEMBL1340140 AC50 5.623 nM
COc1cccc(Cn2c(=O)c(-c3cccs3)nc3cnc(N(C)C)nc32)c1 CHEMBL1514819 Potency 6.3 nM
CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O CHEMBL1396177 Potency 6.3 nM
C#CCCCO/N=C1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3C(=O)N(c4ccc(F)cc4F)C(=O)[C@@H]3CC[C@@H]12 CHEMBL1321847 Potency 6.3 nM
CCCc1cc2c(n1Cc1ccc(OC)cc1)C(C)C1CN(C(=O)c3ccccc3)C(C)(C(=O)OC)C21 CHEMBL1520442 Potency 6.3 nM
O=C(c1csnn1)N1CCC2(CC1)CN(C(c1ccccc1)c1ccccc1)C2 CHEMBL1552314 Potency 6.3 nM
CO[C@@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C\[C@@H](C)[C@H](OC)COC(=O)[C@@H](C)NC(=O)C/C=C\[C@H]1C CHEMBL1450117 Potency 6.3 nM
C/C(CCN1CCc2nc(-c3ccccc3)c(-c3ccccc3)cc2C1)=N\O[C@@H](C)c1cc(-c2c(C)cc(C)cc2C)no1 CHEMBL1476084 Potency 6.3 nM
O=C(O)CC1(C(=O)O)CCCCC1 CHEMBL1487140 Potency 6.3 nM
Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C CHEMBL453 Potency 6.3 nM
O=C(c1ccco1)N1CCC2(CCCN(c3ccncc3)C2)CC1 CHEMBL1513648 Potency 6.3 nM
COc1ccc(/C=C/C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1 CHEMBL1349366 AC50 6.31 nM
CC(=O)Nc1ccc(C#Cc2ccc(NC(C)=O)cc2)cc1 CHEMBL1425861 AC50 6.31 nM
CCCCOc1ccc(-n2ccnc2)cc1 CHEMBL112532 IC50 7.0 nM
CN(/C=C/C1=[N+](C)c2ccccc2C1(C)C)c1ccccc1 CHEMBL1485727 AC50 7.079 nM
COC(=O)[C@@]1(Cc2ccccc2)[C@H]2c3cc(C(=O)N4CCCC4)n(CCO)c3C[C@H]2CN1C(=O)c1ccccc1 CHEMBL1565724 Potency 7.9 nM
NCCSc1nc(-c2ccccc2)c(-c2ccccc2)o1 CHEMBL1320474 Potency 7.9 nM
COc1ccccc1-c1ccc2ncnc(NCc3cccnc3)c2c1 CHEMBL1436169 Potency 7.9 nM
FC(F)(F)c1ccccc1-c1ccc2ncnc(NCc3cccnc3)c2c1 CHEMBL1356336 Potency 7.9 nM
CCS(=O)(=O)Nc1cccc(C(=C2CCCCC2)c2c[nH]cn2)c1 CHEMBL362863 Potency 7.9 nM
O=C(O)c1cccc(S(=O)(=O)NCCO)c1 CHEMBL1448325 Potency 7.9 nM
C/C(CCC(=O)OC[C@@H]1O[C@H](C#Cc2ccccc2)C=C[C@@H]1Oc1ccc(C)cc1)=N/O[C@@H](C)c1cn([C@H](CO)Cc2ccccc2)nn1 CHEMBL1375469 Potency 7.9 nM
COC(=O)NC(/C(C(=O)OC)=C(\C)NCc1ccccc1)c1ccccc1 CHEMBL1475108 Potency 7.9 nM
CCc1ccc(N(C(=O)CNC(=O)c2cccs2)C(C(=O)NC(C)(C)C)c2cc(OC)c(OC)c(OC)c2)cc1 CHEMBL1444936 AC50 7.943 nM
CC(C)(C)c1ccc(SCCc2c[nH]cn2)cc1 CHEMBL1098230 IC50 8.5 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)c3c(n[nH]c3C)[C@@]12C CHEMBL5278512 IC50 9.0 nM
Nc1ccc(C(=O)NC2CCC(=Cc3cccc(Oc4ccc(C(F)(F)F)cn4)c3)CC2)cn1 CHEMBL4557596 IC50 9.1 nM
CC(C)(C)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL17157 Potency 10.0 nM
C=C(C)C(=O)OCC1CN2C(CCC(C)C2c2ccc(Br)cc2)C(=O)O1 CHEMBL1451823 Potency 10.0 nM
CC(C)=CCC/C(C)=C/COc1c2ccoc2cc2oc(=O)ccc12 CHEMBL1078442 Potency 10.0 nM
FC(F)(F)c1cc(CO[C@H]2CCCN[C@H]2c2ccccc2)cc(C(F)(F)F)c1 CHEMBL27006 Potency 10.0 nM
Clc1ccccc1-c1ccc2ncnc(NCc3cccnc3)c2c1 CHEMBL1480806 Potency 10.0 nM
COc1cc2c(cc1OC)C(CCN)=NCC2 CHEMBL1374028 Potency 10.0 nM
O=C1c2ccccc2-c2ccc(/N=[N+](\[O-])c3ccc4c(c3)C(=O)c3ccccc3-4)cc21 CHEMBL1361902 Potency 10.0 nM
C[C@@H](c1ccccc1)N1C(=O)[C@H]2[C@H]3[C@H](O)[C@H](O)C/C(=N/OCc4ccccc4)[C@H]3CC[C@@H]2C1=O CHEMBL1322126 Potency 10.0 nM
Clc1ccc(CS[C@@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL1446716 Potency 10.0 nM
FC(F)(F)c1ccccc1-c1cncnc1NCCc1cnc[nH]1 CHEMBL1590156 Potency 10.0 nM
NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 CHEMBL41631 Potency 10.0 nM
COc1cccc(-c2cncnc2NCCc2cnc[nH]2)c1 CHEMBL1515449 Potency 10.0 nM
C=CCO[C@@H](Cn1ccnc1)c1ccc(Cl)cc1Cl CHEMBL1359713 Potency 10.0 nM
CCN(CC)S(=O)(=O)c1cc(C(=O)Nc2ccncc2)ccc1Cl CHEMBL1613268 AC50 10.0 nM
CCc1cccc2c(C=C(C#N)C#N)cn(CC(=O)N3CCCCCC3)c12 CHEMBL1534554 AC50 10.0 nM
CCOc1cc(NC(=O)c2ccccc2[N+](=O)[O-])c(OCC)cc1NC(=O)CC(C)C CHEMBL1742335 AC50 11.22 nM
COc1cccc(-c2ccc3ncnc(NCc4cccnc4)c3c2)c1 CHEMBL566899 AC50 12.59 nM
COc1cccc([C@@H]2Oc3ccc(OC)cc3/C(=N/O[C@@H](C)CN3CCCCc4nc(C)c(C)cc43)[C@@H]2O)c1 CHEMBL1555164 AC50 12.59 nM
Cc1ccc(S(=O)(=O)n2c3ccccc3c3nnc(C(=O)c4ccccc4)nc32)cc1 CHEMBL1514221 AC50 12.59 nM
Clc1ccccc1-c1cncnc1NCCc1cnc[nH]1 CHEMBL1314367 AC50 12.59 nM
COc1ccc(CCCOc2cc(CCn3ccnc3)ccc2OC)cc1 CHEMBL1332270 AC50 12.59 nM
N#Cc1cccc(-c2ccc3ncnc(NCc4cccnc4)c3c2)c1 CHEMBL1554721 AC50 12.59 nM
Cc1nc(/N=N\c2ccc(S(=O)(=O)O)cc2S(=O)(=O)O)c(COP(=O)(O)O)c(C=O)c1O CHEMBL1437958 AC50 12.59 nM
N[C@H](CCP(=O)(O)O)C(=O)O CHEMBL1319383 AC50 12.59 nM
CC(C)=NO[C@@H](C)CN1CCCc2nc(C)c(C)cc21 CHEMBL1514604 AC50 12.59 nM
C=C(C)C(O)/C=C/c1cccc(OC)c1 CHEMBL1602632 Potency 12.6 nM
Nc1ccc2[nH]cc(CCC(=O)O)c2c1 CHEMBL1491245 Potency 12.6 nM
COC(=O)[C@@H]1[C@@H](O)[C@@H](C(=O)OC)[C@H](C)N(C)[C@@H]1C CHEMBL1489941 Potency 12.6 nM
OCC1OC(C#Cc2ccccc2)C=CC1OCc1ccccc1 CHEMBL1433742 Potency 12.6 nM
C[C@H](CCC(=O)O)[C@H]1CC[C@]2(C)[C@@H]3C(=O)C[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@@]12C CHEMBL1370644 Potency 12.6 nM
N#CC1=C(N)Oc2cc(Nc3ccccc3)ccc2C1c1ccncc1 CHEMBL1450096 AC50 14.13 nM
CN1CCc2cc3c(cc2[C@@H]1[C@H]1OC(=O)c2c1ccc1c2OCO1)OCO3 CHEMBL1316579 Potency 15.8 nM
O=C(O)CC1(CC(=O)O)Nc2ccccc2SC1=O CHEMBL1573554 Potency 15.8 nM
CC[C@H](Oc1ccc(Cl)cc1)C(=O)OC1C[C@H]2CC[C@@H](C1)N2C CHEMBL1553498 Potency 15.8 nM
Cc1ccc(OCCOCCn2ccnc2)c(Br)c1 CHEMBL1444394 AC50 15.85 nM
O=C(Cc1ccc(Cl)cc1)Nc1cccc(-c2nnc(-c3ccco3)o2)c1 CHEMBL1332225 AC50 15.85 nM
O=C(O)/C=C\C(=O)NCc1ccccc1 CHEMBL402467 AC50 15.85 nM
COC(=O)[C@H](CCSC)NC(=O)NCc1ccccc1F CHEMBL1392170 AC50 15.85 nM
O=C(NCC1CCCO1)c1cccc(F)c1 CHEMBL1367355 AC50 15.85 nM
Cc1ccc(/C=C/C(=O)c2nc3ccccc3[nH]2)cc1 CHEMBL1508837 AC50 15.85 nM
Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 CHEMBL104 IC50 16.0 nM
CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 CHEMBL998 IC50 16.0 nM
Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL1221 IC50 16.0 nM
COc1ccc(N(CC(=O)N/N=C/c2cccs2)S(=O)(=O)c2ccc(OC)c(OC)c2)cc1 CHEMBL2002517 AC50 17.78 nM
Cc1ccc(NC(=O)CN2CCC(NC(=O)Cc3ccccc3)CC2)cc1C CHEMBL1600038 AC50 17.78 nM
Cc1cc(C(C)(C)C)cc(CNC2CCCCC2)c1O CHEMBL1399994 AC50 19.95 nM
O=S(=O)(c1cccc(C(F)(F)F)c1)N1c2ccccc2-n2cccc2[C@H]1c1cccnc1 CHEMBL1329102 AC50 19.95 nM
Cc1noc(C)c1-c1ccc2ncnc(NCc3cccnc3)c2c1 CHEMBL585861 AC50 19.95 nM
CSc1ccc(CNc2ccc(Cl)cc2)cc1 CHEMBL1342890 AC50 19.95 nM
O=C(CC1C(=O)N(c2ccc(Cl)cc2)C(=S)N1CCc1ccncc1)Nc1ccc(F)cc1 CHEMBL1450860 AC50 19.95 nM
CN1CCc2cc3c(cc2[C@@H]1[C@@H]1C(=O)Oc2c1ccc1c2OCO1)OCO3 CHEMBL1321655 AC50 19.95 nM
C=C(C)C(O)/C=C/c1ccc(Br)cc1 CHEMBL1320943 Potency 20.0 nM
CC1CCC2C(=O)OC(CN=[N+]=[N-])CN2C1c1ccc(Br)cc1 CHEMBL1369874 Potency 20.0 nM
Cc1ccc2[nH]c(SCc3ccccn3)nc2c1 CHEMBL2019024 Ki 20.0 nM
FC(F)(F)c1nc(-c2ccncc2)ncc1-c1nnnn1-c1ccccc1 CHEMBL1402552 AC50 22.39 nM
O=S(=O)(Nc1ccc(Cc2ccncc2)cc1)c1cccs1 CHEMBL1330299 AC50 22.39 nM
O=S(=O)(Nc1ccc(Cc2ccncc2)cc1)c1ccc(Br)cc1 CHEMBL1299525 AC50 22.39 nM
CN(C)c1ccc(/C=C2/C(=O)N(c3ccc([N+](=O)[O-])cc3)N=C2N2CCOCC2)cc1 CHEMBL1466137 AC50 22.39 nM
C/C=C/OC(=O)NC(c1ccccc1)[C@@]1(C(=O)OCC)CCCC1=O CHEMBL1601824 Potency 25.1 nM
COCC(=O)N1CCC2(CCN(Cc3ccncc3)CC2)CC1 CHEMBL1591876 Potency 25.1 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@H]1OC(=O)c1ccccc1C(=O)O CHEMBL1520907 Potency 25.1 nM
S=C(NC1CCCCC1)N1CCC(c2cnc[nH]2)CC1 CHEMBL260374 Potency 25.1 nM
COc1ccc(-c2nc3cnc(OC)nc3n(Cc3cccs3)c2=O)cc1 CHEMBL1487191 Potency 25.1 nM
OC[C@@H]1O[C@@H](n2cnc3c(NC4CCCCC4)ncnc32)[C@@H](O)[C@H]1O CHEMBL1522656 Potency 25.1 nM
Cc1nc2cnc(N3CCOCC3)nc2n(CCc2ccccc2)c1=O CHEMBL1315820 Potency 25.1 nM
O=C1[C@H]2[C@H]3[C@H](O)[C@H](O)C/C(=N/OC[C@@H](O)COCc4ccco4)[C@@H]3CC[C@@H]2C(=O)N1C[C@@H]1CCCO1 CHEMBL1337978 Potency 25.1 nM
O=C([O-])CC[C@@H](NC(=O)c1ccccc1C(=O)[O-])C(=O)[O-] CHEMBL1314622 Potency 25.1 nM
c1cncc(CNc2ncnc3ccc(-c4ccoc4)cc23)c1 CHEMBL1408427 Potency 25.1 nM
O=C(O)CS(=O)(=O)C(c1ccccc1)c1ccccc1 CHEMBL1529857 Potency 25.1 nM
Cc1noc(C)c1-c1cc(NCc2cccs2)ncn1 CHEMBL1484253 Potency 25.1 nM
C(=N/n1cnnc1)\c1cccn1-c1ccccc1 CHEMBL3211204 AC50 25.12 nM
O=S(=O)(Nc1ccc(Cc2ccncc2)cc1)c1ccc(Cl)c(Cl)c1 CHEMBL1390261 AC50 25.12 nM
Cc1ccc(NC(=S)c2nc3ccccc3s2)cc1 CHEMBL1449916 AC50 25.12 nM
Cc1cc(-n2ccnc2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 CHEMBL231306 IC50 26.0 nM
O=C(Nc1nnc(C2CC2)s1)C1Cc2ccccc2CN1S(=O)(=O)c1ccccc1F CHEMBL1536326 AC50 28.18 nM
CC1Cc2ccccc2N1Cc1nc(O)c2ccc(C(F)(F)F)cc2n1 CHEMBL1576031 AC50 28.18 nM
COc1ccc(NC(=O)CSc2nc3ccccc3cc2Cc2ccccc2)cc1 CHEMBL1306717 AC50 28.18 nM
CS(=O)(=O)N(CCN1CCOCC1)c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cc1 CHEMBL1825089 IC50 30.0 nM
Cn1cc(-c2nc3c(N4CCN(Cc5cccnc5)CC4)c(Br)cnc3[nH]2)cn1 CHEMBL3898132 IC50 30.0 nM
Cc1nn(C)c(C)c1-c1nc2c(N3CCN(Cc4cccnc4)CC3)c(Br)cnc2[nH]1 CHEMBL3891461 IC50 30.0 nM
Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ccc(Cl)cc4)CC3)c(Cl)cnc2[nH]1 CHEMBL2207503 IC50 30.0 nM
Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ncon4)CC3)c(Cl)cnc2[nH]1 CHEMBL2207500 IC50 30.0 nM
Cc1ccc(C)c(Nc2c(Cl)cnc3ccc(-c4cnc(C(C)(C)O)nc4)cc23)c1 CHEMBL4779059 IC50 30.0 nM
CC(Nc1c(Cl)cnc2ccc(-c3cnc(C(C)(C)O)nc3)nc12)c1ccccc1F CHEMBL4742065 IC50 30.0 nM
Cn1c(=O)c2nc(CCCCc3nc4c(=O)n(C)c(=S)n(C)c4[nH]3)[nH]c2n(C)c1=S CHEMBL1409097 Potency 31.6 nM
N=c1ccn2c(n1)O[C@@H]1[C@@H](O)[C@H](CO)O[C@H]12 CHEMBL1552021 Potency 31.6 nM
CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=C[C@@H](C5SCCS5)[C@H](OC(C)=O)C[C@]4(C)[C@H]3CC[C@@]12C CHEMBL1514098 Potency 31.6 nM
c1ccc(SC(Sc2ccccc2)c2ccc3c(c2)OCO3)cc1 CHEMBL1602926 Potency 31.6 nM
O=C(c1ccco1)N1CCC2(CC1)CCN(c1ncccn1)CC2 CHEMBL1475574 Potency 31.6 nM
COC(=O)NC(CC(C)=O)c1ccco1 CHEMBL1553243 Potency 31.6 nM
CN(C)c1ccc(-c2cncnc2NCc2cccnc2)cc1 CHEMBL1565525 Potency 31.6 nM
COCCNc1nc(-c2ccccc2Cl)nc2ccccc12 CHEMBL1532720 Potency 31.6 nM
CC(CC(=O)O)(CC(=O)O)C(=O)O CHEMBL1606018 Potency 31.6 nM
CCc1cc2c(nc1CC)CCN(CC/C(C)=N/OC[C@@H](O)[C@@H]1O[C@@H]3OC(C)(C)O[C@@H]3[C@H]1O)C2 CHEMBL1572239 Potency 31.6 nM
CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@@H]1N1CCCC1 CHEMBL58033 Potency 31.6 nM
COC(=O)NC(/C(C(=O)OC)=C(\C)NCc1ccccc1)c1cccs1 CHEMBL1438138 Potency 31.6 nM
Cc1ccc(Nc2nc(-c3c(C)nc4ncccn34)cs2)cc1 CHEMBL1374527 AC50 31.62 nM
O=C(O)C1CCN(c2ncccn2)CC1 CHEMBL1601626 AC50 31.62 nM
CCN1CCN(C(c2cccs2)C(C)NC(=O)c2cccnc2)CC1 CHEMBL1327087 AC50 31.62 nM
CSc1ccc(CNc2ccc(C)c(C)c2)cc1 CHEMBL1467491 AC50 31.62 nM
CCc1oc2ccccc2c1C(=O)c1cc(C)c(O)c(C)c1 CHEMBL225481 Ki 33.0 nM
O=C(c1ccccc1)c1c[nH]c(C(=O)NCCCN2CCOCC2)c1 CHEMBL1441676 AC50 35.48 nM
Cc1cccc(NC(=O)Cn2c(=O)n3nc(CCn4nc(C)cc4C)nc3c3ccccc32)c1 CHEMBL1421758 AC50 35.48 nM
Cc1ccc(N(C(=O)C(F)(F)F)C(C(=O)NC2CCCCC2)c2cccs2)cc1C CHEMBL1741490 AC50 35.48 nM
Cn1ncc([N+](=O)[O-])c1C(=O)Nc1ccc2c(c1)OCCO2 CHEMBL1572174 AC50 35.48 nM
O=C(CNC(=O)OCc1ccccc1)NCC(=O)N1CCCC1C(=O)OCc1ccccc1 CHEMBL1500132 AC50 35.48 nM
Cc1ccc(NC(=O)CN(C)C(=O)CSc2n[nH]c(N)n2)cc1 CHEMBL1492299 AC50 35.48 nM
CCC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036210 IC50 38.0 nM
O=C(N/N=C1/C[C@@H](O)[C@@H](O)[C@@H]2[C@@H]3C(=O)N(c4cccc(Oc5ccccc5)c4)C(=O)[C@H]3CC[C@H]12)OCc1ccccc1 CHEMBL1551732 Potency 39.8 nM
CC(C)CNCCc1ccccn1 CHEMBL1358341 Potency 39.8 nM
Cc1ccc(CNC(=O)[C@H]2C[C@@H]2[C@H](NP(=O)(c2ccccc2)c2ccccc2)c2ccccc2)c(F)c1F CHEMBL1476632 Potency 39.8 nM
O=[N+]([O-])c1ccc(C[As](=O)(O)O)cc1 CHEMBL1373414 Potency 39.8 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL10 Potency 39.8 nM
O=C(Nc1nnn[nH]1)c1nc(O)cc(-c2ccccc2)n1 CHEMBL1410057 Potency 39.8 nM
CNc1ccnc(-c2c(C)noc2C)n1 CHEMBL1395107 Potency 39.8 nM
CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@H]3[C@H]2CC(=O)[C@]2(C)[C@@H]3C[C@@H](N3CC3)[C@H]2C(C)=O)C1 CHEMBL1528540 Potency 39.8 nM
O=c1c(-c2cccc(Cl)c2)nc2cncnc2n1Cc1ccccc1 CHEMBL1323549 Potency 39.8 nM
NCCCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1 CHEMBL1591209 Potency 39.8 nM
Clc1ccccc1CN1CCc2sccc2C1 CHEMBL833 Potency 39.8 nM
COC(=O)NC(c1cccc(C)c1)[C@]1(C(C)=O)CCOC1=O CHEMBL1483716 Potency 39.8 nM
c1ncc(-c2ccc3c(c2)OCO3)c(NCCc2cnc[nH]2)n1 CHEMBL1356060 Potency 39.8 nM
Cn1c(=O)c(-c2ccccc2)nc2cnc(Nc3ccccc3)nc21 CHEMBL1522897 Potency 39.8 nM
Cc1noc(C)c1-c1cncnc1NCCN1CCOCC1 CHEMBL1551567 Potency 39.8 nM
O=S(=O)(c1ccccc1)N1CCC2(CCN(c3ccncc3)CC2)CC1 CHEMBL1593589 Potency 39.8 nM
COc1ccccc1NC(=O)CSc1nc2ccccc2cc1Cc1ccccc1 CHEMBL1569843 AC50 39.81 nM
O=C(Nc1ccccc1N1CCOCC1)c1cnccn1 CHEMBL1407287 AC50 39.81 nM
Cc1cccc(OCCCCCn2ccnc2)c1 CHEMBL1489204 AC50 39.81 nM
COc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 CHEMBL1441823 AC50 39.81 nM
COC(=O)c1ccc(NC(=O)C2CCCCC2C(=O)O)cc1 CHEMBL1302562 AC50 39.81 nM
CC(c1cn(C)nn1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 CHEMBL551784 IC50 40.0 nM
Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL808 IC50 40.0 nM
Clc1ccc(CO/N=C(\Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL1262 IC50 40.0 nM
COc1ccc2[nH]c(SCc3ccc(C(C)C)cc3)nc2c1 CHEMBL2018917 Ki 40.0 nM
COc1ccc2[nH]c(SCc3ccc(I)cc3)nc2c1 CHEMBL2018921 Ki 40.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccncc2)nc2ccc(C(F)(F)F)cc21 CHEMBL3605543 IC50 40.0 nM
CNCCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL41 IC50 40.0 nM
Cc1c(Cl)cccc1NC(=O)c1ccc(-n2ccnc2)nc1 CHEMBL1522673 AC50 44.67 nM
NC(=O)c1ccc2c(c1)CCCN2Cc1ccc(C(=O)NO)cc1 CHEMBL4846435 IC50 47.0 nM
C[C@]12Cc3c[nH]nc3C[C@@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O CHEMBL2079587 IC50 48.0 nM
O=C(CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccc(CCCO)cc1)N/N=C1\C(=O)Nc2ccccc21 CHEMBL2113179 IC50 50.0 nM
CCCCCCCSc1nc2cc(OC)ccc2[nH]1 CHEMBL2018908 Ki 50.0 nM
COc1ccc2[nH]c(SCc3cccc(Oc4ccccc4)c3)nc2c1 CHEMBL2018925 Ki 50.0 nM
c1ccc(CSc2nc3ccccc3[nH]2)nc1 CHEMBL296580 Ki 50.0 nM
CCOc1ccc2c(c1)C(C)=CC(C)(C)N2 CHEMBL172064 Potency 50.1 nM
CN1CCN2c3ncccc3Cc3ccccc3C2C1 CHEMBL654 Potency 50.1 nM
CN1CCc2cc3c(cc2[C@@H]1[C@@H]1OC(=O)c2c1ccc1c2OCO1)OCO3 CHEMBL1437488 Potency 50.1 nM
O=c1c(-c2ccc(F)c(F)c2)nc2cncnc2n1Cc1ccccc1 CHEMBL1407670 Potency 50.1 nM
CC(=O)c1ccc(OCc2ccccc2)c(C)c1O CHEMBL1447147 Potency 50.1 nM
CCCC[C@@H]1C[C@H]1C(NC(=O)Cc1ccccc1)c1ccc(Cl)cc1 CHEMBL1330587 Potency 50.1 nM
Clc1ccc(CSCc2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL1566987 Potency 50.1 nM
CS(=O)(=O)Nc1cccc(-c2ccc3ncnc(NCc4cccnc4)c3c2)c1 CHEMBL1603852 Potency 50.1 nM
COC(=O)[C@@H]1CC[C@H](C)[C@@H](c2ccc(C)cc2)N1C(=O)c1ccc(/C=N\O[C@@H](C)c2cn([C@H](CO)Cc3ccccc3)nn2)cc1 CHEMBL1488873 Potency 50.1 nM
COc1ccc2[nH]cc(CCNc3ncncc3-c3ccccc3C)c2c1 CHEMBL1554577 Potency 50.1 nM
Cc1ccccc1-c1cncnc1NCCc1cnc[nH]1 CHEMBL1404598 Potency 50.1 nM
Cc1cc(O)c(C(C)C)cc1NC(=O)Nc1cccc2ccccc12 CHEMBL1330763 Potency 50.1 nM
COC(=O)[C@@H]1CC[C@H](C)[C@@H](c2ccc(C)cc2)N1C(=O)c1ccc(/C=N\OC[C@@H]2O[C@H](c3ccccc3)C=C[C@@H]2Oc2ccc(OC)cc2)cc1 CHEMBL1612050 Potency 50.1 nM
COc1cc2cc3c4c(cc(OC)c(OC)c4c2cc1OC)CCN3C CHEMBL1412163 Potency 50.1 nM
COc1cccc(Cn2c(=O)c(-c3ccc(F)cc3)nc3cnc(N4CCOCC4)nc32)c1 CHEMBL1484120 Potency 50.1 nM
O[C@@H](COc1cccc2ccccc12)CN1CCOCC1 CHEMBL1457123 Potency 50.1 nM
Cc1ccc(S(=O)(=O)N/N=C/c2cccn2-c2ccc(Cl)cc2)cc1 CHEMBL3213021 AC50 50.12 nM
COc1cccc(C(=O)N(C)c2nnc(-c3ccncc3)s2)c1 CHEMBL1586684 AC50 50.12 nM
Cc1ccc(Nc2ccc(-n3ccnc3)nn2)cc1C CHEMBL1484866 AC50 50.12 nM
CCC(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036213 IC50 51.0 nM
FC(F)(F)c1ccc(SCC(c2ccncc2)c2c[nH]cn2)cc1 CHEMBL1243367 IC50 55.0 nM
O=S(=O)(NCc1cc(-c2ccccc2Cl)no1)c1ccc(Cl)cc1 CHEMBL1526526 AC50 56.23 nM
COc1ccc(/C=C/c2ccncc2)cc1 CHEMBL67212 AC50 56.23 nM
CNC(=O)c1sc(SC)cc1-c1ccc(Cl)cc1 CHEMBL1374373 AC50 56.23 nM
O=C(NCCCn1ccnc1)Nc1ccc(Cl)cc1 CHEMBL1331489 AC50 56.23 nM
CCCN1C(=O)C(Cc2nc3ccccc3c(=O)n2C)c2ccccc21 CHEMBL1352421 AC50 56.23 nM
CC(=O)N(CC(=O)O)c1ccccc1C(=O)O CHEMBL1723692 AC50 56.23 nM
CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1ccncc1 CHEMBL1319717 AC50 56.23 nM
COc1ccc(OC)c(NC(=O)CSc2nc3ccccc3cc2Cc2ccccc2)c1 CHEMBL1607455 AC50 56.23 nM
CCCCCSc1nc2cc(OC)ccc2[nH]1 CHEMBL2018904 Ki 60.0 nM
COc1ccc2[nH]c(SCC(C)C)nc2c1 CHEMBL2018909 Ki 60.0 nM
COc1ccc2nc(SCc3ccc4ccccc4c3)[nH]c2c1 CHEMBL502335 Ki 60.0 nM
N=C(N)NC(=O)c1ccc(C2CCN(C(=O)c3ccncc3)CC2)c(C(F)(F)F)c1 CHEMBL2170635 IC50 60.0 nM
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc(-c2cnco2)cc1 CHEMBL3110021 IC50 60.0 nM
CC(C)C(c1nncn1C)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 CHEMBL552156 IC50 63.0 nM
NS(=O)(=O)c1nc(S(=O)(=O)O)c2[nH]cnc2n1 CHEMBL1447721 Potency 63.1 nM
C[C@@H]1CCC[C@H](C)N1 CHEMBL1517793 Potency 63.1 nM
COc1ccc(O[C@H]2C=C[C@@H](c3ccccc3)O[C@H]2COC(=O)CC/C(C)=N\O[C@@H](C)c2cn([C@H](CO)Cc3ccccc3)nn2)cc1 CHEMBL1320406 Potency 63.1 nM
CC(C)CO[C@H](c1ccc2c(c1)OCO2)[C@H](C)Br CHEMBL1314273 Potency 63.1 nM
COc1ccc2[nH]cc(CCNc3ncncc3-c3ccccc3Cl)c2c1 CHEMBL1592464 Potency 63.1 nM
COCCCC/C(=N/OCCN)c1ccc(C(F)(F)F)cc1 CHEMBL1314286 Potency 63.1 nM
O=c1c(CCc2ccccc2)nc2cnc(N3CCOCC3)nc2n1CCc1ccccc1 CHEMBL1437447 Potency 63.1 nM
Cc1c2cccc(Sc3ccccc3)c2c2c3c(cccc13)[S+](c1ccccc1)C2 CHEMBL1354190 Potency 63.1 nM
COc1ccccc1CNc1ncncc1-c1ccc(N(C)C)cc1 CHEMBL489738 Potency 63.1 nM
C#C[C@@]1(O)CC[C@@H]2[C@@H]3CCC4=C(CCC(=O)C4)[C@H]3CC[C@]21C CHEMBL1480126 Potency 63.1 nM
COc1ccc(C#CC2C=CC(Oc3cc(C)cc(C)c3)C(CO)O2)cc1 CHEMBL1492577 Potency 63.1 nM
COCOc1ccc(Br)cc1C(=O)[C@H]1O[C@H]1c1cccc(OC)c1 CHEMBL1559163 Potency 63.1 nM
COC(=O)NC(/C(C(=O)OC)=C(\C)NCc1ccccc1)c1ccc2ccccc2c1 CHEMBL1513115 Potency 63.1 nM
COc1cccc([C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c3cn([C@H](CO)Cc4ccccc4)nn3)[C@@H]2O)c1 CHEMBL1447538 Potency 63.1 nM
C=CCN1C[C@H](C)N([C@@H](c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)C[C@H]1C CHEMBL153648 Potency 63.1 nM
C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@H]5S[C@H]5C[C@]43C)[C@H]1CC[C@H]2O CHEMBL1357770 Potency 63.1 nM
NCCC[C@@H](CC(=O)N[C@@H]1CCCC[C@H]1C(=O)N[C@H](CC(=O)N[C@@H](CCC(=O)O)CC(=O)O)Cc1ccccc1)NC(=O)C[C@H](CO)NC(=O)[C@@H]1CCCC[C@H]1N CHEMBL1533895 Potency 63.1 nM
c1ccc2c(c1)[I+]c1ccccc1-2 CHEMBL365739 Potency 63.1 nM
Clc1ccccc1-c1nc(-c2ccncc2)no1 CHEMBL1402420 Potency 63.1 nM
COCOc1ccc(Br)cc1C(=O)/C=C\c1ccc2c(c1)OCO2 CHEMBL1573532 Potency 63.1 nM
O=c1ccc2c(OCCCCc3ccccc3)c3ccoc3cc2o1 CHEMBL1256851 Potency 63.1 nM
Clc1ccc(CO[C@@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL1232474 Potency 63.1 nM
CC(C)=CCC/C(C)=C/CO/N=C1/C[C@@H](O)[C@@H](O)[C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@H]3CC[C@H]12 CHEMBL1435210 Potency 63.1 nM
Nc1n[nH]c(SCC(=O)Nc2ccccc2Sc2ccc(Cl)cc2)n1 CHEMBL1611048 AC50 63.1 nM
Cc1oc2ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)cc2c1C(=O)Nc1ccccc1 CHEMBL1550048 AC50 63.1 nM
CCOc1ccc(CCNC(=O)C2CC(=O)N(C3CCCC3)C2)cc1OCC CHEMBL1742330 AC50 63.1 nM
COc1ccc(S(=O)(=O)N2CCCN(CC(=O)Nc3ccc(OC)c(Cl)c3)CC2)cc1 CHEMBL1527911 AC50 63.1 nM
COc1nnc(OC)c2ccccc12 CHEMBL1384975 AC50 63.1 nM
Cc1nc(C(C)N(Cc2ccccc2Cl)c2ccc(C#N)c(Cl)c2)cs1 CHEMBL551782 IC50 67.0 nM
CCCCOc1ccc(-n2cncn2)cc1 CHEMBL345544 IC50 68.0 nM
CCCCCCSc1nc2cc(OC)ccc2[nH]1 CHEMBL2018907 Ki 70.0 nM
COc1ccc2[nH]c(SCc3ccc(Br)cc3)nc2c1 CHEMBL2018920 Ki 70.0 nM
COc1cc(CSc2nc3ccc(OC)cc3[nH]2)cc(OC)c1 CHEMBL488400 Ki 70.0 nM
COc1ccc2[nH]c(SCc3cccc(-c4ccccc4)c3)nc2c1 CHEMBL2018923 Ki 70.0 nM
Fc1ccccc1N(Cc1ccc(Cl)cc1)C1CNC1 CHEMBL3331506 IC50 70.0 nM
Cc1cc(C(=O)C(=O)NC(C)C)c(C)n1-c1ccc([N+](=O)[O-])cc1 CHEMBL1415809 AC50 70.79 nM
O=C1C2ON(c3ccccc3)C(c3ccncc3)C2C(=O)N1c1ccccc1 CHEMBL1464487 AC50 70.79 nM
O=C(/C=C/c1cccc(Cl)c1)Nc1ccncc1 CHEMBL1505191 AC50 70.79 nM
Cc1cc2cc(C=O)c(Cl)nc2cc1C CHEMBL1447520 AC50 70.79 nM
CCCCn1c(SCC(=O)Nc2nccs2)nc2ccccc2c1=O CHEMBL1526199 AC50 70.79 nM
CC(=O)N(/N=C/c1cccc(C)c1)c1nc(-c2ccc(Br)cc2)cs1 CHEMBL3198545 AC50 70.79 nM
CCCCn1nnnc1SCC(=O)c1cc(Cl)ccc1OC CHEMBL1360026 AC50 70.79 nM
O=C(Nc1ccc(F)cc1)c1ccc(-n2ccnc2)nc1 CHEMBL1573171 AC50 70.79 nM
Nc1c(-c2cccs2)cnn1-c1nc(-c2ccc(Cl)cc2Cl)cs1 CHEMBL1533645 AC50 70.79 nM
CCc1ccc(C(=O)COC(=O)C(Cc2ccccc2)NC(=O)C2CCC(C)CC2)cc1 CHEMBL1582783 AC50 70.79 nM
NCCCCCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 CHEMBL1331148 Potency 79.4 nM
COc1ccc2[nH]cc(CCNc3ncncc3-c3ccccc3OC)c2c1 CHEMBL1316956 Potency 79.4 nM
CC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1 CHEMBL1536007 Potency 79.4 nM
N#Cc1ccccc1-c1ccc2ncnc(NCc3cccnc3)c2c1 CHEMBL1513990 Potency 79.4 nM
COc1ccccc1-c1cncnc1NCCc1cnc[nH]1 CHEMBL1396261 Potency 79.4 nM
Oc1ccc(Cl)cc1Sc1cc(Cl)ccc1O CHEMBL473535 Potency 79.4 nM
COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 CHEMBL1355088 Potency 79.4 nM
Clc1ccc([C@H](Cn2ccnc2)OCc2c(Cl)cccc2Cl)c(Cl)c1 CHEMBL1327203 Potency 79.4 nM
CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1OC1CCCCC1 CHEMBL7162 Potency 79.4 nM
C=COCC1CN2C(CCC(C)C2c2ccc(Br)cc2)C(=O)O1 CHEMBL1395138 Potency 79.4 nM
O=C1CCc2c(ccc3ccccc23)O1 CHEMBL86537 Potency 79.4 nM
CN(C)c1ccc(-c2cncnc2NCCc2cnc[nH]2)cc1 CHEMBL1318495 Potency 79.4 nM
O=C1[C@H]2[C@H]3[C@H](O)[C@H](O)C/C(=N/OCc4ccccc4)[C@H]3CC[C@@H]2C(=O)N1C[C@@H]1CCCO1 CHEMBL1315351 Potency 79.4 nM
CN1[C@@H](c2ccccc2)C/C(=N\O)C[C@H]1c1ccccc1 CHEMBL1408347 Potency 79.4 nM
COC(=O)N1CCC[C@@]2(CCN(c3ccccc3)C2)C1 CHEMBL1551308 Potency 79.4 nM
Nc1ccc(S(=O)(=O)NCc2nccs2)cc1 CHEMBL1370903 Potency 79.4 nM
O=c1[nH]c(=S)[nH]c(-c2ccccc2)c1Cc1c(O)ccc2ccccc12 CHEMBL491960 Potency 79.4 nM
C#C[C@@]1(O)CC[C@@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]21CC CHEMBL1571929 Potency 79.4 nM
O=C1C(SCCO)=C(SCCO)C(=O)c2ccccc21 CHEMBL429095 Potency 79.4 nM
NC1(C(=O)O)CCCCC1 CHEMBL559934 Potency 79.4 nM
OCC1OC(c2ccc3c(c2)OCO3)C=CC1Oc1cc(Cl)cc(Cl)c1 CHEMBL1448192 Potency 79.4 nM
COc1ccc2c(c1OC)C(=O)O[C@H]2[C@H]1c2cc3c(cc2CCN1C)OCO3 CHEMBL475536 Potency 79.4 nM
CCCC[C@@H]1C[C@H]1C(NC(=O)c1cccs1)c1ccc(Cl)cc1 CHEMBL1603781 Potency 79.4 nM
Cc1cc2nc(O)c([C@H](C)C(=O)c3ccc(Cl)cc3)nc2cc1C CHEMBL1411609 Potency 79.4 nM
CNc1ncnc(Sc2nc(N)nc3[nH]cnc23)c1[N+](=O)[O-] CHEMBL1318140 Potency 79.4 nM
CCCNC(=O)OC[C@@H]1O[C@H](CCO/N=C(\C)CCC(=O)OC[C@@H]2O[C@H](c3ccccc3)C=C[C@@H]2Oc2ccc(OC)cc2)C=C[C@@H]1Oc1ccc(OC)cc1 CHEMBL1316213 Potency 79.4 nM
c1ccc2c(CSCCc3ccncc3)cccc2c1 CHEMBL1586705 AC50 79.43 nM
OC1(c2ccc(OC(F)F)cc2)CS/C(=N\c2cccnc2)N1C1CC1 CHEMBL1999906 AC50 79.43 nM
CCCc1cc2c(cc1NC(=O)c1ccc(Br)cc1)OCO2 CHEMBL1329418 AC50 79.43 nM
CCSc1ncc(/C=N/Nc2ccc(F)cc2)n1C CHEMBL3211761 AC50 79.43 nM
COc1ccc(/C=N/OCc2nc3c4c(ncn3n2)Oc2ccc3ccccc3c2C4c2ccccc2)cc1 CHEMBL3213001 AC50 79.43 nM
Nc1nonc1-c1nc2ccccc2n1Cc1ccc(F)cc1Cl CHEMBL1390396 AC50 79.43 nM
Cc1ccc(NC(=O)c2cc([N+](=O)[O-])ccc2NCc2cccnc2)cc1Cl CHEMBL533542 AC50 79.43 nM
CC(c1nnnn1C(C)C)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 CHEMBL564015 IC50 80.0 nM
O=C(c1sc2ccccc2c1Cl)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1311461 AC50 89.13 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1OC CHEMBL1492815 AC50 89.13 nM
COC(=O)c1ccc(NC(=O)Cn2nc(-c3ccncc3)nc2SCC(=O)Nc2nccs2)cc1 CHEMBL1464417 AC50 89.13 nM
COc1ccc(S(=O)(=O)Nc2ccc(F)cc2)c(C)c1C CHEMBL1381005 AC50 89.13 nM
CCOC(=O)C1(N(CC)CC)Sc2cc(C)ccc2NC1=O CHEMBL1403311 AC50 89.13 nM
O=C(OCc1ccc(Cl)cc1)c1ccccc1C(=O)c1ccccc1 CHEMBL1312757 AC50 89.13 nM
c1cn(-c2ccc(OCCN3CCOCC3)cc2)cn1 CHEMBL113018 IC50 91.0 nM
Cc1nnc(C(C)N(Cc2ccccc2Cl)c2ccc(C#N)c(Cl)c2)o1 CHEMBL559581 IC50 91.0 nM