O=C(O)c1ccc(CNc2ccc(-c3ccc(-c4nc5cc(Cl)ccc5[nH]4)cn3)cn2)cc1 CHEMBL4577468 IC50 2.5 nM
Cn1c(C2(NC(=O)c3ccc4c(C5CCCC5)c(-c5ncc(Br)cn5)n(C)c4c3)CCC2)nc2ccc(/C=C/C(=O)O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)cc21 CHEMBL4066318 Ki 22.0 nM
CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ccncc5)CC4)ccc3C)cc12 CHEMBL4086080 IC50 26.0 nM
CCC(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036213 IC50 43.0 nM
CS(=O)(=O)c1ccc(CN(C(=O)Cc2ccccc2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036225 IC50 50.0 nM
CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)[O-])CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1 CHEMBL1200681 Km 50.0 nM
CCC(=O)N(Cc1ccc(S(C)(=O)=O)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036220 IC50 54.0 nM
CC(C)CC(=O)N(Cc1ccc(S(C)(=O)=O)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036222 IC50 79.0 nM
Fc1ccc(-c2cc(Nc3ccncc3)c3cc[nH]c3n2)c(F)c1 CHEMBL4446613 pIC50 79.43 nM
CCC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036210 IC50 86.0 nM
C=CC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(C(N)=O)c(Oc2ccc(Oc3ccccc3)cc2)n1 CHEMBL4242598 IC50 100.0 nM
Fc1cc(F)c(-c2cc(Nc3ccncc3)c3cc[nH]c3n2)cc1Cl CHEMBL4437930 pIC50 100.0 nM
CC(C)(C)n1nnnc1C(c1cccc(Nc2ccnc3cc(Cl)ccc23)c1)N1CCCC1 CHEMBL2413882 IC50 120.0 nM
CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)O)CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1 CHEMBL787 IC50 130.0 nM
CC(C)OC(c1cccc(C(F)(F)F)c1)c1nc(-n2ccc(NC(=O)c3cscn3)cc2=O)c[nH]1 CHEMBL3810042 IC50 180.0 nM
Cn1cc(S(=O)(=O)N2CCC3=Cc4c(cnn4-c4ccc(F)cc4)C[C@]3(C(=O)c3cc(C(F)(F)F)ccn3)C2)cn1 CHEMBL4068611 IC50 210.0 nM
CS(=O)(=O)c1ccc(CN(C(=O)C2CCCC2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036223 IC50 220.0 nM
CCN(CC)C(c1cccc(Nc2ccnc3cc(Cl)ccc23)c1)c1nnnn1C(C)(C)C CHEMBL2413881 IC50 220.0 nM
COc1ccc2[nH]c(SCc3cccc(-c4ccccc4)c3)nc2c1 CHEMBL2018923 IC50 250.0 nM
CCCc1ccncc1-c1ccc(CN)o1 CHEMBL4169721 IC50 260.0 nM
C=CC1(C=C)Oc2c(NC(=O)Nc3ccc(C)cc3)cc(-c3ccccc3-c3nn[nH]n3)cc2[C@@H]1c1ccccc1 CHEMBL5279540 IC50 270.0 nM
CNC(C)C(=O)Nc1ccc(-c2c(-c3ccncc3)nc3cc(C)ccn23)c(C#Cc2ccc3ncccc3c2)n1 CHEMBL3925961 IC50 300.0 nM
CNC(C)C(=O)Nc1ccc(-c2c(-c3ccncc3)nc3cc(C)ccn23)c(C#Cc2ccc(-c3ccon3)cc2)n1 CHEMBL3969750 IC50 300.0 nM
Cc1cnc(-c2cc(F)ccc2F)cc1Nc1ccnc2cn[nH]c12 CHEMBL4102696 pIC50 316.23 nM
CCCCC(=O)N(Cc1ccc(OC)cc1)c1cccc(-c2nnn[nH]2)c1 CHEMBL2036017 IC50 320.0 nM
CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5cccnc5)CC4)ccc3C)cc12 CHEMBL4096241 IC50 350.0 nM
Cc1cnc(-c2cc(Cl)ccc2F)cc1Nc1ccnc2cn[nH]c12 CHEMBL4084771 pIC50 398.11 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(-n3ccnc3)cc2)cc1 CHEMBL2425146 IC50 400.0 nM
COc1cc2nc([C@@H](CNC(=O)c3c(Cl)cc(-n4cnc(C)n4)cc3Cl)c3cccc(F)c3)[nH]c2cc1Cl CHEMBL3627894 IC50 456.0 nM
CCC(=O)N(Cc1cccc(OC(C)C)c1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036030 IC50 470.0 nM
CNC(C)C(=O)Nc1ccc(-c2c(-c3ccncc3)nc3cc(C)ccn23)c(C#Cc2ccc3nc(C)ccc3c2)n1 CHEMBL3910478 IC50 500.0 nM
COCCOCCn1nc(C)c2c1CSCc1cc(n(C)n1)CSc1cc(c3ccccc3c1)OCCCn1c(C(=O)O)c(C)c3c-2c(Cl)ccc31 CHEMBL5437247 pIC50 501.19 nM
COc1ccc2nc(SCc3ccc4ccccc4c3)[nH]c2c1 CHEMBL502335 IC50 510.0 nM
N[C@@H]1c2ccccc2OC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5412197 IC50 530.0 nM
CCCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cccc(-c2nnn[nH]2)c1 CHEMBL2036203 IC50 570.0 nM
c1ccc2oc(-c3csc(C4CCN(Cc5nc6cnccc6[nH]5)CC4)n3)cc2c1 CHEMBL5086239 IC50 590.0 nM
Fc1ccc(-c2cc(Nc3ccncc3)c3cc[nH]c3n2)cc1F CHEMBL4526347 pIC50 630.96 nM
COc1ccc2[nH]c(SCc3ccc(OCc4ccccc4)cc3)nc2c1 CHEMBL2018926 IC50 680.0 nM
O=C(O)[C@H]1CC[C@H](C(=O)N2CC[C@](c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3)(S(=O)(=O)c3ccc(F)cc3)C2)CC1 CHEMBL3934548 IC50 680.0 nM
O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)N1CCc2ncccc2[C@@H]1c1ccc(Cl)cc1 CHEMBL4537998 IC50 700.0 nM
O=C(N[C@H]1C[C@@H]1c1ccccc1)N1CCC(Oc2ccc(-c3nn[nH]n3)cc2)CC1 CHEMBL3114608 IC50 800.0 nM
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 CHEMBL3647052 IC50 800.0 nM
Cc1cccc2c(-c3ncc4c(n3)N3CCOC[C@@]3(C)C(=O)N4[C@H]3CC[C@@H](O)CC3)c[nH]c12 CHEMBL5416106 IC50 800.0 nM
Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 CHEMBL104 IC50 803.0 nM
C[C@H](c1ccnc(Nc2nc3ccc(-c4cc(N(C)C)ncn4)cc3[nH]2)c1)N1CCN(C(=O)CC(F)(F)F)CC1 CHEMBL4537673 IC50 860.0 nM
C[C@@H](c1ccc(C(F)(F)F)cc1C(F)(F)F)n1cc(NC(=O)c2cc(-c3ccccn3)on2)cn1 CHEMBL5088282 IC50 860.0 nM
Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)c2)c2c(N)ncnc21 CHEMBL2171124 IC50 890.0 nM
CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccnc(C)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1 CHEMBL3911035 IC50 900.0 nM
O=C(Nc1cnn(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)c1)c1cc(-c2ccco2)on1 CHEMBL5073329 IC50 960.0 nM
COc1ccc2[nH]c(SCc3ccc(C(C)(C)C)cc3)nc2c1 CHEMBL2018918 IC50 970.0 nM
CCC(=O)N(Cc1cccc(O)c1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036217 IC50 970.0 nM
Nc1ccc2[nH]c(SCc3ccccn3)nc2c1 CHEMBL2019026 IC50 990.0 nM
CNC(=O)Nc1ccc2c(c1)CC[C@@]21OC(=O)N(CC(=O)N(Cc2ccccc2)[C@@H](C)C(F)(F)F)C1=O CHEMBL4174931 IC50 990.0 nM
CC(=O)Nc1cccc(-c2ccc3nc(-c4cccnc4N)n(-c4ccc(CNC(=O)c5cccc(F)c5)cc4)c3n2)c1 CHEMBL2177836 IC50 1000.0 nM
CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ccccn5)CC4)ccc3C)cc12 CHEMBL4078188 IC50 1000.0 nM
CC(C)COc1ncc(-c2cn(C)c3cc(C(=O)NS(C)(=O)=O)ccc23)cc1Cl CHEMBL4279180 IC50 1000.0 nM
CC(C)COc1ccc(-c2cn(C)c3cc(C(=O)NS(C)(=O)=O)c(F)cc23)cn1 CHEMBL4550045 IC50 1000.0 nM
CC(=O)Nc1cccc(-c2ccc3nc(-c4cccnc4N)n(-c4ccc(C5(N)CCC5)cc4)c3n2)c1 CHEMBL4519558 IC50 1000.0 nM
O=C(NCc1ncc(C(F)(F)F)cc1Cl)c1ccc2c(c1)C1(CCS(=O)(=O)CC1)[C@H](C1CC1)N2S(=O)(=O)c1ccc(F)cc1 CHEMBL4537788 IC50 1000.0 nM
Cc1nn([C@H](C)c2ccc(C(F)(F)F)cc2C(F)(F)F)cc1NC(=O)c1cc(-c2ccccn2)on1 CHEMBL5075836 IC50 1000.0 nM
COc1cc(OCc2csc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 CHEMBL3716552 IC50 1000.0 nM
C=C[C@H]1Oc2c(NC(=O)Nc3ccc(C)cc3)cc(-c3ccccc3-c3nn[nH]n3)cc2[C@@H]1c1ccccc1 CHEMBL5285519 IC50 1000.0 nM
Cc1cccc2c(-c3ncc4c(n3)N3CCOC[C@@]3(C)C(=O)N4C3CCOCC3)c[nH]c12 CHEMBL5424319 IC50 1000.0 nM