C[C@@H](Nc1c(Nc2ccn[nH]2)c(=O)c1=O)c1ccccc1 CHEMBL524472 IC50 0.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N CHEMBL180672 IC50 0.045 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccccc1C#N CHEMBL382741 IC50 0.1 nM
C[C@H](NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 CHEMBL220360 IC50 0.59 nM
c1ccc2c(c1)nnn2CN1CCOCC1 CHEMBL1492579 Potency 1.0 nM
CC(=O)OCC1OC(C#Cc2ccccc2)C=CC1OC(C)=O CHEMBL1361285 Potency 1.0 nM
COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc3[nH]c(=O)[nH]c23)cc1 CHEMBL486278 IC50 1.26 nM
CC[C@@H]1CN2CC[C@@H]1C[C@H]2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL1531111 Potency 1.6 nM
CC(=O)N1CCN(c2ccc(OC[C@H]3CO[C@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 CHEMBL75 IC50 1.86 nM
C[C@@H](c1cccnc1)c1c(CCN(C)C)sc2ccccc12 CHEMBL1091778 IC50 2.0 nM
C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL1294 IC50 2.0 nM
O=C(Nc1cccc2ccccc12)c1ccccc1 CHEMBL1330614 Potency 2.5 nM
CO[C@@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@H]1Cc1cn(C)c3cccc2c13 CHEMBL1377111 Potency 2.5 nM
CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(-c3cccnc3)cc2)c2ccc(OCc3ccccn3)cc12 CHEMBL538632 IC50 2.6 nM
CCOC(=O)CCc1ccc(OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c(C#N)c1 CHEMBL1204009 IC50 3.0 nM
O=CN1Cc2cc(S(=O)(=O)CC3CC3)ccc2C1C(=O)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4857395 IC50 3.0 nM
Cc1ccc(SCc2n[nH]c3c2C(C(C)C)C(C#N)=C(N)O3)cc1 CHEMBL1450157 AC50 3.162 nM
Cc1cccc(C(=O)N2CCC(c3nc(-c4ccc(S(=O)(=O)N5CCOCC5)cc4)no3)CC2)c1 CHEMBL1611066 AC50 3.162 nM
CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(-c3nccs3)cc2)c2ccc(OCc3ccccn3)cc12 CHEMBL539650 IC50 4.0 nM
CC1CCC2C(=O)N3CCCC3C(=O)N2C1c1ccc(Br)cc1 CHEMBL1528848 Potency 4.0 nM
CC(C)N1CCC(c2ccccc2)(c2ccccc2)CC1 CHEMBL277382 Ki 4.8 nM
c1ccc2c(c1)ncn2-c1ncnc2sc3c(c12)CCCC3 CHEMBL1598281 AC50 5.012 nM
CC(=O)c1c(O)cc(=O)n(-c2ccccc2)c1-c1ccc(C)cc1 CHEMBL1543028 AC50 5.012 nM
Cn1cc(-c2nc3c(N4CCN(Cc5cccnc5)CC4)c(Br)cnc3[nH]2)cn1 CHEMBL3898132 IC50 5.5 nM
CCCN1C(=O)C(NC(C)=O)c2cc(OC)ccc21 CHEMBL1301946 AC50 5.623 nM
CCOC(=O)c1c(-c2ccccc2)nc2c(C)cccn12 CHEMBL1446244 AC50 5.623 nM
Cc1nc2c(C#N)cnn2c(O)c1Cc1ccccc1 CHEMBL1519083 AC50 5.623 nM
Cc1cc([N+](=O)[O-])nn1CC(=O)NN=C(S)Nc1ccc(F)cc1 CHEMBL1464982 AC50 5.623 nM
O=C(c1ccc(COc2ccc(F)cc2)o1)n1cccn1 CHEMBL1407398 AC50 5.623 nM
CC(=O)Nc1ccc(OCC(O)Cn2cnc3ccccc32)cc1 CHEMBL1742034 AC50 5.623 nM
COc1ccc(Oc2nccc(-c3ccc(F)cc3)c2C#N)cc1 CHEMBL1519391 AC50 5.623 nM
COc1cc(/C=C/C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc(OC)c1OC CHEMBL1339210 AC50 5.623 nM
O=C(O)C1=CCCN(CCON=C(c2ccccc2)c2ccccc2)C1 CHEMBL473104 Potency 6.3 nM
c1ccc(CN2CCC3(CCc4ccccc43)CC2)cc1 CHEMBL292477 Potency 6.3 nM
CC[C@H](Oc1ccc(Cl)cc1)C(=O)OC1C[C@H]2CC[C@@H](C1)N2C CHEMBL1553498 Potency 6.3 nM
C[C@@H](c1ccccc1)N1C(=O)[C@H]2[C@H]3[C@H](O)[C@H](O)C/C(=N/OCc4ccccc4)[C@@H]3CC[C@@H]2C1=O CHEMBL1475200 Potency 6.3 nM
CNCCCCCCCCSc1nc(C(C)C)ccc1C(=O)c1cccs1 CHEMBL1514639 Potency 6.3 nM
CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1 CHEMBL129529 Potency 6.3 nM
CC1(C)CO[C@H](CC(=O)O)CN1 CHEMBL1395421 Potency 6.3 nM
CN(CCc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@H]1N1CCCC1 CHEMBL106437 Potency 6.3 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2c3cccc4c3c(cn4C)C[C@@H]21 CHEMBL1441920 Potency 6.3 nM
C=CC(C)(C)c1[nH]c2ccccc2c1C1=C(O)C(O)=C(c2c[nH]c3c(CC=C(C)C)cccc23)C(=O)C1=O CHEMBL18879 Potency 6.3 nM
Oc1ccnc2cccc(Cc3ccccc3)c12 CHEMBL1323499 AC50 7.079 nM
Clc1ccc2c(c1)N(CCCN1CCCC13CCCCC3)c1ccccc1S2 CHEMBL1448562 Potency 7.9 nM
COC(=O)NC(c1ccccc1)C(C(=O)OC)C(=O)OC CHEMBL1454280 Potency 7.9 nM
CC[N+](CC)(CC(=O)Nc1c(C)cccc1C)Cc1ccccc1 CHEMBL1371493 Potency 7.9 nM
CN1[C@@H]2CC[C@H]1CC(OC(=O)c1cc(Cl)cc(Cl)c1)C2 CHEMBL1365455 Potency 7.9 nM
C=CC1CN2CCC1CC2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL97 Potency 7.9 nM
CCCCNc1nccc2[nH]c3ccccc3c12 CHEMBL497171 pIC50 7.943 nM
COc1ccc(C(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)cc1OC CHEMBL1741648 AC50 7.943 nM
COc1cccc(/C=N/NC(=O)c2cc(-c3cccn3C)[nH]n2)c1 CHEMBL3189451 AC50 7.943 nM
O=C(Nc1ccccc1)C(Cc1ccccc1)NC(=O)C12CC3CC(CC(C3)C1)C2 CHEMBL1511412 AC50 7.943 nM
CN[C@H]1CCc2ccccc2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL1642914 IC50 8.0 nM
COC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL15245 IC50 8.4 nM
O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc2n(n1)C(C(F)(F)F)CC(c1ccco1)N2 CHEMBL1559062 AC50 8.913 nM
C=C[C@H]1CN2CCC1CC2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL3923804 IC50 9.0 nM
CNCCc1sc2ccccc2c1[C@@H](C)c1ccccn1 CHEMBL1093044 IC50 9.8 nM
COC(=O)N1CC[C@@H](NC(=O)Nc2nc(C)c(C(C)=O)s2)[C@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 CHEMBL400173 IC50 10.0 nM
COc1ccccc1CN1CC[C@@]2(CCCN(S(=O)(=O)c3ccccc3)C2)C1 CHEMBL1446922 Potency 10.0 nM
CCN(CC)C(=O)N[C@@H]1C[C@H]2c3cccc4[nH]cc(c34)C[C@@H]2N(C)C1 CHEMBL1433815 Potency 10.0 nM
CN1CCN2c3ccccc3Cc3ccccc3[C@@H]2C1 CHEMBL1329927 Potency 10.0 nM
CN1[C@H](CC(=O)c2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1 CHEMBL1571589 Potency 10.0 nM
C[C@@H](CN(C)C)CN1c2ccccc2Sc2ccccc21 CHEMBL2062336 Potency 10.0 nM
C[C@@H](Cc1ccccc1)NCCC(c1ccccc1)c1ccccc1 CHEMBL1317618 Potency 10.0 nM
CN1[C@@H](CC(=O)c2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1 CHEMBL1371478 Potency 10.0 nM
C=C[C@H]1CN2CC[C@@H]1C[C@H]2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL1365872 Potency 10.0 nM
COc1ccccc1C[C@@H](Cc1nc2ccccc2[nH]1)c1nc2ccccc2[nH]1 CHEMBL1326787 Potency 10.0 nM
CCc1ccc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1 CHEMBL1489961 AC50 10.0 nM
O=C(O)c1ccc2c(c1)C(=O)N(C(Cc1ccc(O)cc1)C(=O)O)C2=O CHEMBL258538 AC50 10.0 nM
Cc1ccc(Nc2nc(-c3sc(NC(=O)c4ccc([N+](=O)[O-])cc4)nc3C)cs2)cc1 CHEMBL1458544 AC50 10.0 nM
Cc1ccccc1NC(=O)CN1CCC(n2nnc3ccccc32)CC1 CHEMBL1718033 AC50 10.0 nM
Cc1c(C(=O)N/N=C/c2ccccc2)sc(=S)n1C CHEMBL3211748 AC50 10.0 nM
Cc1ccc(C)c(C(=O)CN2C3=NCCCN3c3ccccc32)c1 CHEMBL1404928 AC50 10.0 nM
Cc1ccc(C(=O)Nc2cc3c(oc2=O)CCCC3=O)cc1 CHEMBL1432053 AC50 10.0 nM
c1ccc(N(Cc2ccc3ccccc3c2)C2CNC2)cc1 CHEMBL3331469 IC50 10.0 nM
CC(C)CC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 CHEMBL3577939 IC50 10.0 nM
C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12 CHEMBL170 IC50 10.0 nM
CC(=O)N1Cc2cc(S(=O)(=O)CC3CC3)ccc2C1C(=O)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4877500 IC50 10.0 nM
CNC[C@@H]1C[C@H](c2ccc(OC(F)(F)F)cc2)N1Cc1ccccc1OC(F)(F)F CHEMBL5399557 IC50 10.0 nM
CNS(=O)(=O)c1ccc2c(c1)CC(C(=O)N(C)[C@H](CN1CC[C@H](O)C1)c1ccccc1)O2 CHEMBL383586 IC50 11.0 nM
CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12 CHEMBL16596 IC50 11.0 nM
CC[n+]1c(C=CN(C)c2ccccc2)sc2ccc(Cl)cc21 CHEMBL1312953 AC50 11.22 nM
CCOC(=O)c1c(-c2ccccc2)csc1NC(=O)c1cccc(N2C(=O)CCC2=O)c1 CHEMBL1371959 AC50 11.22 nM
COCC(=O)N1Cc2cc(S(=O)(=O)CC3CC3)ccc2C1C(=O)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4865776 IC50 12.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL275311 AC50 12.59 nM
COc1ccc(-c2nnn(CC(=O)NCCc3c[nH]c4ccccc34)n2)cc1OC CHEMBL1735424 AC50 12.59 nM
CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H](CN1CCCC1)c1ccccc1 CHEMBL38576 AC50 12.59 nM
c1ccc([C@H]2NCCc3c2[nH]c2ccccc32)cc1 CHEMBL1355855 AC50 12.59 nM
C[C@@H](Cc1cccc(C(F)(F)F)c1)NCCCc1ccccc1 CHEMBL1611225 AC50 12.59 nM
O=C(c1ccc(F)cc1)C1CCN(CCCCc2ccccc2)CC1 CHEMBL19259 AC50 12.59 nM
OC(Cn1c2ccccc2c2ccccc21)C[n+]1ccccc1 CHEMBL1330926 AC50 12.59 nM
CCOc1c(Cl)cc(C(=O)Nc2ccccc2-c2ccccc2)cc1Cl CHEMBL1536139 AC50 12.59 nM
COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 CHEMBL325109 AC50 12.59 nM
O=C(CCCNC(=O)/C(=C\c1ccccc1F)NC(=O)c1ccccc1)OCc1ccccc1 CHEMBL1441359 AC50 12.59 nM
O=C(c1cc2cc(Cl)ccc2[nH]1)N1C[C@]2(CCN(C3CCNC3)C2)c2ccccc21 CHEMBL1933536 IC50 14.0 nM
CC(C)COC[C@H](CN(Cc1ccccc1)c1ccccc1)N1CCCC1 CHEMBL251075 Potency 15.8 nM
C[C@@H](Cc1cccc(C(F)(F)F)c1)NCCOC(=O)c1ccccc1 CHEMBL1592316 Potency 15.8 nM
CCCN(C/C=C\I)[C@@H]1CCc2ccc(O)cc2C1 CHEMBL1552249 Potency 15.8 nM
C[N+](C)(CCCOc1ccccc1)c1ccccc1 CHEMBL1573957 Potency 15.8 nM
Cc1ccc(S(=O)(=O)/C=C\C#N)cc1 CHEMBL1562420 Potency 15.8 nM
CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c1ccccc1 CHEMBL282567 Potency 15.8 nM
Clc1ccc([C@@H](OCCN2CCCCC2)c2ccccc2)cc1 CHEMBL1516068 Potency 15.8 nM
CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL841 Potency 15.8 nM
CCN(CC)C(=O)N[C@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL157138 IC50 16.0 nM
COC(=O)C1=CO[C@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 CHEMBL2079609 Ki 17.0 nM
O=c1c2ccccc2nc(-c2ccc(Cl)cc2Cl)n1CCCn1ccnc1 CHEMBL1416438 AC50 17.78 nM
COc1ccc(CN(C(=O)c2cccs2)C(C(=O)NC2CCCCC2)c2ccc3ncccc3c2)cc1 CHEMBL1495397 AC50 17.78 nM
CN(C(=O)Cc1ccccc1CN)[C@H](CN1CCCC1)c1ccccc1 CHEMBL192677 IC50 18.0 nM
Fc1ccc2c(c1CNc1ncc(-c3cccnc3)c3nncn13)CCO2 CHEMBL5202962 IC50 19.0 nM
COc1ccccc1CN1CCC2(CC1)CCN(S(C)(=O)=O)CC2 CHEMBL1354644 AC50 19.95 nM
CC[C@@]12CCCN3CCc4c(n(c5ccccc45)C(=O)C1)[C@H]32 CHEMBL1318553 AC50 19.95 nM
CN(C)CCN(Cc1ccc(Cl)cc1)c1ccccn1 CHEMBL1194287 AC50 19.95 nM
N#CC(=C(/N)Sc1ccccc1N)/C(C#N)=C(/N)Sc1ccccc1N CHEMBL100473 AC50 19.95 nM
CC[N+](CC)(CC)CCC(O)(c1ccccc1)C1CCCCC1 CHEMBL1201354 AC50 19.95 nM
C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL3707183 IC50 20.0 nM
COc1ccc(OC(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 CHEMBL319118 Ki 20.0 nM
COc1cc2c(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)C(C(F)(F)F)CC2 CHEMBL478620 Ki 20.0 nM
O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1-c1ccccc1 CHEMBL522295 IC50 20.0 nM
CN[C@@H]1Cc2ccccc2[C@H](c2ccc(Cl)c(Cl)c2)C1 CHEMBL1642896 IC50 20.0 nM
Cc1cc(C[C@H](CCCCNCc2ccc(F)cc2)C(=O)NO)cc(C)c1F CHEMBL1760324 IC50 20.0 nM
COc1ccc2[nH]c(SCc3cccc(-c4ccccc4)c3)nc2c1 CHEMBL2018923 IC50 20.0 nM
Fc1ccccc1N(Cc1ccc(Cl)cc1)C1CNC1 CHEMBL3331506 IC50 20.0 nM
CC(C)N(C)[C@@H]1CC[C@H](NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)[C@H](CCc2ccccc2)C1 CHEMBL3577940 IC50 20.0 nM
CC(=O)N1Cc2cc(S(=O)(=O)NC3CC3)ccc2C1C(=O)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4868864 IC50 20.0 nM
OCCN1CCN(C(=S)c2ccc(Br)cc2)CC1 CHEMBL1487101 AC50 22.39 nM
CC(O)(CS(=O)(=O)c1cccc(C(F)(F)F)c1)C(=O)Nc1ccc(C(F)(F)F)cc1 CHEMBL1742326 AC50 22.39 nM
Cc1cc2ccccc2c[n+]1CC(O)C[n+]1cc2ccccc2cc1C CHEMBL1516485 Potency 25.1 nM
C[C@@H](C(=O)Nc1ccc2ccccc2c1)[C@H]1C[C@]1(C)[C@H](NC(=O)c1cccnc1)c1ccccc1 CHEMBL1408528 Potency 25.1 nM
O=S(=O)(c1ccccc1)N1CCC[C@@]2(CCN(Cc3ccccc3)C2)C1 CHEMBL1480779 Potency 25.1 nM
CN(C)c1ncnc2c1ncn2CCn1cnc2c(N(C)C)ncnc21 CHEMBL1414688 Potency 25.1 nM
COC(=O)[C@@H]1[C@@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL1327758 Potency 25.1 nM
O=C(c1ccncc1)N1CCC2(CC1)CN(C(c1ccccc1)c1ccccc1)C2 CHEMBL1598334 Potency 25.1 nM
CN1C[C@H](CO)C=C2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL39947 Potency 25.1 nM
C/C(=N/O)c1ccc2cc(Br)c3ccccc3c2c1 CHEMBL1611220 Potency 25.1 nM
COc1cc(/C=C(\C#N)C(N)=O)cc(CSc2nc3ccccc3s2)c1O CHEMBL118109 Potency 25.1 nM
COc1ccc(C(=O)N2CCC3(CCCN(Cc4nccs4)C3)CC2)cc1 CHEMBL1456714 Potency 25.1 nM
CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc1ccc(OC)cc1 CHEMBL282121 Potency 25.1 nM
COc1cc2c(cc1OC)C(=O)Cc1ccc3c(c1CN(C)CC2)OCO3 CHEMBL1339015 Potency 25.1 nM
COc1ccccc1NC(=O)CN1CCN(C2c3ccccc3-c3ccccc32)CC1 CHEMBL1431735 AC50 25.12 nM
COc1cccc(SCc2noc(C(=O)NCC3CCCO3)c2C(=O)O)c1 CHEMBL1419019 AC50 25.12 nM
Cc1ccc(/C=N/NC(=O)c2cccs2)cc1[N+](=O)[O-] CHEMBL3197340 AC50 25.12 nM
COc1cc(OC)c2c(C)[n+](-c3ccc(C)cc3)c(C)cc2c1 CHEMBL520612 Ki 28.1 nM
Cc1ccc(N2C(=O)/C(=C/N3CCN(C(=O)c4ccco4)CC3)C(=O)NC2=S)cc1C CHEMBL1351579 AC50 28.18 nM
CCOc1ccc(CCNC(=O)C2CC(=O)N(C3CCCC3)C2)cc1OCC CHEMBL1742330 AC50 28.18 nM
CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1cccc2ccccc12 CHEMBL179332 IC50 30.0 nM
CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccccc1 CHEMBL95499 IC50 30.0 nM
CN(CC(O)COc1ccccc1C#N)C(C)(C)Cc1cc2ccccc2[nH]1 CHEMBL435551 IC50 30.0 nM
c1ccc(OCCCN2CCC(Cc3c[nH]cn3)CC2)cc1 CHEMBL200267 IC50 30.0 nM
Clc1cccc(CN(CC2CC2)[C@H]2CCNC2)c1Cl CHEMBL246920 IC50 30.0 nM
CC(=O)c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 CHEMBL250689 IC50 30.0 nM
Cn1nnnc1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 CHEMBL363840 IC50 30.0 nM
CCCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCCN1 CHEMBL1224165 IC50 30.0 nM
Cc1nn(C)c(C)c1-c1nc2c(N3CCN(Cc4cccnc4)CC3)c(Br)cnc2[nH]1 CHEMBL3891461 IC50 30.0 nM
Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ccc(Cl)cc4)CC3)c(Cl)cnc2[nH]1 CHEMBL2207503 IC50 30.0 nM
Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ncon4)CC3)c(Cl)cnc2[nH]1 CHEMBL2207500 IC50 30.0 nM
Cc1nc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5cn(C)nc5C)nc34)CC2)no1 CHEMBL2207501 IC50 30.0 nM
c1ccc2c(c1)CN[C@@H](CN(CC[C@@H]1CCCNC1)[C@H]1CCCc3cccnc31)C2 CHEMBL4163611 IC50 30.0 nM
FC(F)Oc1cc(-n2cc(Cn3ccnc3)nn2)ccc1Cl CHEMBL5432620 IC50 30.0 nM
COC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@H]1O CHEMBL2079555 Ki 31.0 nM
CCCN1C[C@H](CSC)C[C@H]2c3cccc4[nH]cc(c34)C[C@@H]21 CHEMBL1408844 Potency 31.6 nM
COC(=O)N[C@H](c1ccccc1)[C@@]1(C)C[C@@H]1[C@@H](C)C(=O)Nc1ccc2ccccc2c1 CHEMBL1359917 Potency 31.6 nM
CCN(CC)C(=O)N[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@@H]2N(C)C1 CHEMBL1489822 Potency 31.6 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL567 Potency 31.6 nM
CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1ccccn1 CHEMBL434063 Potency 31.6 nM
CCNc1ncc2nc(-c3cccc(C#N)c3)c(=O)n(CCC#N)c2n1 CHEMBL1592804 Potency 31.6 nM
CN1CCc2cc(Br)c(O)cc2[C@H](c2ccccc2)C1 CHEMBL1473849 Potency 31.6 nM
COc1cc2c(cc1O)[C@H]1Cc3ccc(OC)c(O)c3CN1CC2 CHEMBL1395394 Potency 31.6 nM
COc1ccccc1CN1CCC2(CCNCC2)CC1 CHEMBL1363967 Potency 31.6 nM
CN1C[C@@H](CNC(=O)OCc2ccccc2)C[C@H]2c3cccc4c3c(cn4C)C[C@@H]21 CHEMBL1515750 Potency 31.6 nM
CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1ccncc1 CHEMBL1319717 AC50 31.62 nM
Cn1c(CN2CCCCC2)nc2cc(NC(=O)c3ccc(Cl)cc3)ccc21 CHEMBL1408140 AC50 31.62 nM
O=C(c1ccc2c(c1)OCCO2)C1CCN(S(=O)(=O)c2ccccc2F)CC1 CHEMBL1441572 AC50 31.62 nM
Cc1ccc2nc(-c3ccccc3)c(CN(C)C)c(O)c2c1 CHEMBL1312169 AC50 31.62 nM
Cc1c(Cl)cccc1NC(=O)c1ccc(-n2ccnc2)nc1 CHEMBL1522673 AC50 31.62 nM
NCc1cccc(CN(C[C@H]2Cc3ccccc3CN2)[C@H]2CCCc3cccnc32)c1 CHEMBL4075694 IC50 32.0 nM
CN[C@@H]1CCc2ccccc2[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL1642915 IC50 33.0 nM
CC(=O)NCc1ccccc1CC(=O)N(C)[C@H](CN1CCCC1)c1ccccc1 CHEMBL539685 IC50 35.0 nM
COC(=O)c1c(C)oc2ccc(N(C(=O)c3ccncc3)S(=O)(=O)c3ccccc3)cc12 CHEMBL1319426 AC50 35.48 nM
Cn1c(=O)n(C)c2cc([N+](=O)[O-])c(N3CCN(C(=O)c4ccccc4Cl)CC3)cc21 CHEMBL1310415 AC50 35.48 nM
Cn1c(-c2ccc(F)cc2)cnc1NCc1ccc(F)cc1 CHEMBL1589340 AC50 35.48 nM
Cc1ccc(-c2nnc(-c3ccccc3S(=O)(=O)Cc3ccc(Cl)cc3)o2)cc1 CHEMBL1383143 AC50 35.48 nM
COc1ccc(-c2coc3cc(OC)cc(O)c3c2=O)cc1 CHEMBL464433 AC50 35.48 nM
COc1ccc(CC(C)(C)NCC(O)COc2ccccc2C#N)cc1 CHEMBL504479 IC50 36.0 nM
O=C(O)C1(C(=O)O)CCN(S(=O)(=O)c2ccccc2)CC1 CHEMBL1253921 Potency 39.8 nM
CN[C@H](Cc1ccccc1)c1cccc(OC)c1O CHEMBL1438867 Potency 39.8 nM
CCN(CC)C(=O)N[C@H]1C[C@H]2c3cccc4[nH]cc(c34)C[C@@H]2N(C)C1 CHEMBL1315160 Potency 39.8 nM
CNc1ccnc(-c2ccccc2CN(C)C)n1 CHEMBL1452272 Potency 39.8 nM
O=C(c1ccncc1)N1CCC2(CCCN(C(c3ccccc3)c3ccccc3)C2)CC1 CHEMBL1492346 Potency 39.8 nM
Cc1cc(C(=O)N[C@H](c2ccccc2)[C@@]2(C)C[C@@H]2[C@@H](C)C(=O)Nc2ccc3ccccc3c2)n(C)n1 CHEMBL1363234 Potency 39.8 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@H]1OC(=O)c1ccccc1C(=O)O CHEMBL1520907 Potency 39.8 nM
Clc1ccc(C(c2ccc(Cl)cc2)[n+]2ccn(C[C@@H](OCc3ccc(Cl)cc3Cl)c3ccc(Cl)cc3Cl)c2)cc1 CHEMBL1594216 Potency 39.8 nM
O=C(O)c1ccc(/C=N\N=C2c3ccccc3-c3ccccc32)cc1 CHEMBL1611012 Potency 39.8 nM
CC(C)C(=O)c1c(C(C)C)nn2ccccc12 CHEMBL19449 Potency 39.8 nM
CN(C)Cc1ccccc1-c1cc(NC2CC2)ncn1 CHEMBL1611893 Potency 39.8 nM
CN1CCN(C2=Cc3ccccc3Oc3ccc(Cl)cc32)CC1 CHEMBL90882 Potency 39.8 nM
Cc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1 CHEMBL762 Potency 39.8 nM
c1ccc(CCCCN2CCC(c3ccccc3)CC2)cc1 CHEMBL325238 Potency 39.8 nM
N=C(Nc1ccc(I)cc1)NC1C2CC3CC(C2)CC1C3 CHEMBL1484738 Potency 39.8 nM
COc1ccc(Br)cc1C(=O)Nc1ccc(Cc2ccncc2)cc1 CHEMBL1374962 AC50 39.81 nM
C=CCN(CC(O)COc1ccccc1C#N)C(C)(C)Cc1cc2ccccc2[nH]1 CHEMBL367605 IC50 40.0 nM
CCc1ncnc2cc(OCC(O)CNC(C)(C)Cc3cc4ccccc4[nH]3)c(OC)cc12 CHEMBL178206 IC50 40.0 nM
Cc1cc(OCC(O)CNC(C)(C)Cc2cc3ccccc3[nH]2)ccc1S(C)(=O)=O CHEMBL181322 IC50 40.0 nM
O=C(CCN1CCC(Cc2c[nH]cn2)CC1)Nc1ccc(Cl)cc1 CHEMBL371730 IC50 40.0 nM
CCCCC1CNCCN1c1ccc2[nH]ncc2c1 CHEMBL1172525 IC50 40.0 nM
CCCCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224492 IC50 40.0 nM
O=c1c2ccccc2c(Cc2ccc(Cl)cc2)nn1C[C@H]1CCCN1CCCCc1ccc(OCCCN2CCCCCC2)cc1 CHEMBL1767164 IC50 40.0 nM
Cc1nc2ccccc2n1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 CHEMBL3799799 IC50 40.0 nM
Fc1ccc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)cc1 CHEMBL490 IC50 40.0 nM
COc1ccc2c(c1)[C@]13CCCC[C@@H]1[C@H](C2)N(C)CC3 CHEMBL52440 IC50 40.8 nM
CNC[C@H]1Cc2ccccc2[C@H](c2ccc(Cl)c(Cl)c2)C1 CHEMBL1642906 IC50 41.0 nM
CC(C)C[C@@H](CO)NCC(=O)N1CCc2ccccc2C1C1CCCCC1 CHEMBL3600880 IC50 44.0 nM
CCC(=O)Nc1ccc(N2CCN(CC)CC2)c(Cl)c1 CHEMBL1478425 AC50 44.67 nM
Cc1ccc(SCc2ccc(C(=O)NCc3ccncc3)cc2)cc1 CHEMBL1418864 AC50 44.67 nM
O=C(CCN1C(=O)c2ccccc2C1=O)NC(=S)Nc1cccc(Cl)c1 CHEMBL1326093 AC50 44.67 nM
CC(=O)NCCn1c(SCC(=O)NCc2ccco2)nc2ccccc2c1=O CHEMBL1567805 AC50 44.67 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N CHEMBL2112075 IC50 45.0 nM
CN(C(=O)Cc1ccccc1)[C@H](CN1CCCC1)c1ccccc1 CHEMBL94734 IC50 46.0 nM
NCc1ccc(CN(C[C@H]2Cc3ccccc3CN2)[C@H]2CCCc3cccnc32)cc1 CHEMBL4078260 IC50 48.0 nM
CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccccc1C#N CHEMBL321582 IC50 50.0 nM
CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1c(C#N)ccc2ccccc12 CHEMBL178100 IC50 50.0 nM
COc1ccc2[nH]cc(CC(C)(C)NCC(O)COc3ccccc3C#N)c2c1 CHEMBL317164 IC50 50.0 nM
CC(C)(Cc1csc2ccccc12)NCC(O)COc1ccccc1C#N CHEMBL361947 IC50 50.0 nM
CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccc(F)cc1C#N CHEMBL179338 IC50 50.0 nM
CC(=O)c1sc(NC(=O)N[C@@H]2CCN(C(=O)C(C)C)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C CHEMBL250262 IC50 50.0 nM
Cc1cc(OCC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)cc(C)n1 CHEMBL253528 IC50 50.0 nM
c1ccc(CC2CNCCN2c2ccc3[nH]ncc3c2)cc1 CHEMBL1171975 IC50 50.0 nM
CC(C)CCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224320 IC50 50.0 nM
C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 CHEMBL1201284 IC50 50.0 nM
COc1ccc2c(=O)c(O)c(-c3ccc4c(c3)OCO4)oc2c1 CHEMBL4450031 IC50 50.0 nM
O=c1ccc2c(OCCCCc3ccccc3)c3ccoc3cc2o1 CHEMBL1256851 Potency 50.1 nM
FC(F)(F)c1cc(CO[C@H]2CCCN[C@H]2c2ccccc2)cc(C(F)(F)F)c1 CHEMBL27006 Potency 50.1 nM
COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]2c3cc(C(=O)N(C)C)n(CCc4ccc(OC)c(Br)c4)c3C[C@H]2CN1C(=O)c1ccccc1 CHEMBL1409320 Potency 50.1 nM
C[C@@H]1O[C@H](O[C@@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@@H](C6=CC(=O)OC6)CC[C@@]5(O)[C@@H]4CC[C@]3(O)C2)[C@@H](O)[C@H](O)[C@H]1O CHEMBL1493751 Potency 50.1 nM
CCc1cc(Cl)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O CHEMBL8946 Potency 50.1 nM
CCN=C=NCCCN(C)C CHEMBL1397523 Potency 50.1 nM
CN1CCc2cc3c(cc2C(=O)Cc2ccc4c(c2C1)OCO4)OCO3 CHEMBL453019 Potency 50.1 nM
COc1ccc2c(c1)N(CC[C@H]1CCCCN1C)c1ccccc1S2 CHEMBL1533467 Potency 50.1 nM
CSC(=N)N CHEMBL1358112 Potency 50.1 nM
C[C@H](NC[C@H](O)CP(=O)(O)Cc1ccccc1)c1ccc(Cl)c(Cl)c1 CHEMBL455185 Potency 50.1 nM
O=S(=O)(c1ccccc1)N1CCC2(CCCN(Cc3ccccc3)C2)CC1 CHEMBL1593443 Potency 50.1 nM
CC(C)c1cc(F)cc2c1C[C@](CCN(C)CCCc1nc3ccccc3[nH]1)(OC(=O)C1CC1)CC2 CHEMBL1356120 Potency 50.1 nM
CN(C)CCCN1c2ccccc2Sc2ccccc21 CHEMBL564 Potency 50.1 nM
CC1=NCC[N@@+]1(CCc1ccccc1)Cc1ccccc1 CHEMBL1491684 Potency 50.1 nM
CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1OC1CCCCC1 CHEMBL7162 Potency 50.1 nM
CCOC(=O)C1C(=O)NC(C)C1c1ccccc1 CHEMBL1342908 AC50 50.12 nM
CC(/C=C/c1ccccc1)=N/NC(=O)CNC(=O)c1ccc2c(c1)OCO2 CHEMBL1967062 AC50 50.12 nM
N#CC1=C(N)Oc2cc(Nc3ccccc3)ccc2C1c1ccncc1 CHEMBL1450096 AC50 50.12 nM
Fc1ccc(CN2CCN(c3nc4cnccc4nc3NC3CC3)CC2)c(F)c1 CHEMBL4598390 pIC50 50.12 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccc(CCC(=O)O)cc1 CHEMBL572163 IC50 52.0 nM
COc1cc(OC)c2c(C)[n+](-c3ccc(C(C)C)cc3)c(C)cc2c1 CHEMBL481022 Ki 54.7 nM
CC1CCC(N[C@@H]2CCN(C(=O)N3CC[C@H](N(C)C(=O)c4ccc(-c5ccc(C(F)(F)F)cc5)cc4)C3)C2)CC1 CHEMBL215920 IC50 55.0 nM
CC(=O)N/N=C/c1cc([N+](=O)[O-])ccc1OCCOc1ccccc1 CHEMBL3209973 AC50 56.23 nM
Cn1c(-c2ccc(F)cc2)cnc1NCc1cccc(F)c1 CHEMBL1524183 AC50 56.23 nM
COc1cc(CNCc2cccs2)cc(Br)c1OC CHEMBL1353889 AC50 56.23 nM
CN[C@@H]1CCc2ccccc2[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL1642916 IC50 57.0 nM
C/C(CN)=C(\F)CN(C[C@H]1Cc2ccccc2CN1)[C@H]1CCCc2cccnc21 CHEMBL4161528 IC50 59.0 nM
CN(C)CCC1(O)c2ccccc2CCc2ccc3ccccc3c21 CHEMBL380748 IC50 60.0 nM
CC(=O)c1sc(NC(=O)N[C@@H]2CCN(C(=O)C3CC3)C[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C CHEMBL251274 IC50 60.0 nM
c1ccc(CCC2CNCCN2c2ccc3[nH]ncc3c2)cc1 CHEMBL1170373 IC50 60.0 nM
COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C CHEMBL45816 IC50 63.0 nM
O[C@H]1C[C@H]2CC[C@@H](C1)N2CCCN1c2ccccc2Sc2ccc(Cl)cc21 CHEMBL3349050 Potency 63.1 nM
C[C@@H](CNC1CCCCC1)OC(=O)c1ccccc1 CHEMBL1604244 Potency 63.1 nM
COc1cc2c(cc1OC)[C@@H]1C(=O)c3ccc4c(c3O[C@@H]1CO2)C=CC(C)(C)O4 CHEMBL393417 Potency 63.1 nM
CC(C)=CCC/C(C)=C/COc1c2ccoc2cc2oc(=O)ccc12 CHEMBL1078442 Potency 63.1 nM
CCCNC[C@H](O)COc1ccccc1C(=O)CCc1ccccc1 CHEMBL1322675 Potency 63.1 nM
CCNc1ncc2nc(-c3cc(F)cc(F)c3)c(=O)n(CCC#N)c2n1 CHEMBL1315129 Potency 63.1 nM
COc1ccc2c(c1)N(C[C@@H](C)CN(C)C)c1ccccc1S2 CHEMBL1323355 Potency 63.1 nM
COc1ccccc1CN1CCCC2(CCN(S(C)(=O)=O)CC2)C1 CHEMBL1591170 Potency 63.1 nM
Ic1ccccc1CN[C@@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1 CHEMBL1513555 Potency 63.1 nM
Cn1cc(C(=O)C(=O)N[C@H]2CN3CCC2CC3)c2ccccc21 CHEMBL294649 Potency 63.1 nM
O=C1NCN(c2ccccc2)C12CCN(C[C@H]1COc3ccccc3O1)CC2 CHEMBL1358012 Potency 63.1 nM
Nc1ccncc1 CHEMBL284348 Potency 63.1 nM
CCNc1ncc2nc(CCc3ccccc3)c(=O)n(C[C@H]3CCCO3)c2n1 CHEMBL1405546 Potency 63.1 nM
C[C@H](c1ccccc1)N1CCN([C@@H](C)c2ccccc2)CC1 CHEMBL1524227 Potency 63.1 nM
COc1ccc2c(c1OC)CN1CCc3cc4c(cc3[C@H]1C2)OCO4 CHEMBL476501 Potency 63.1 nM
O=C(CSc1nccn1-c1ncc(C(F)(F)F)cc1Cl)c1ccc(Cl)cc1 CHEMBL1539107 AC50 63.1 nM
COc1ccccc1CCNCc1cc2c(cc1[N+](=O)[O-])OCO2 CHEMBL1472129 AC50 63.1 nM
O=C(c1ccccc1Oc1ccccc1)N(CC1CCC1)[C@H]1CCNC1 CHEMBL549584 IC50 65.0 nM
NC1=N[C@@]2(c3cc(NC(=O)c4ccc(OC(F)F)cn4)ccc3F)COCC[C@H]2CS1 CHEMBL3973534 IC50 65.0 nM
CCC1CN2CCC1CC2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL2092739 Ki 66.0 nM
CN[C@H]1Cc2ccccc2[C@H](c2ccc(Cl)c(Cl)c2)C1 CHEMBL1642894 IC50 67.0 nM
CC(C)(C)[C@@H](CO)NCC(=O)N1CCc2ccccc2C1C1CCCCC1 CHEMBL3600879 IC50 68.0 nM
CCc1ncnc2cc(OC)c(OCC(O)CNC(C)(C)Cc3cc4ccccc4[nH]3)cc12 CHEMBL180620 IC50 70.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1cccc(C)c1C CHEMBL498482 IC50 70.0 nM
COc1ccc(C(C)C(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 CHEMBL513351 Ki 70.0 nM
O=C(c1cc(F)c2[nH]ccc2c1)C1(Cc2ccccc2)CCNC1 CHEMBL1224563 IC50 70.0 nM
COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCOc2ccc(F)cc2)CC1OC CHEMBL1729 IC50 70.0 nM
CCN1/C(=C/c2ccc3cccc(C)c3[n+]2CC)Sc2ccccc21 CHEMBL1404792 AC50 70.79 nM
CCOC(=O)c1c(N=C(S)Nc2ccccc2)sc2c1CCN(CCc1ccccc1)C2 CHEMBL1488727 AC50 70.79 nM
CC(NCc1ccc(Cl)cc1)C(O)c1ccccc1 CHEMBL1304293 AC50 70.79 nM
CCOC(=O)C1CCCN(C/C=C/c2ccccc2[N+](=O)[O-])C1 CHEMBL1428605 AC50 70.79 nM
CCCCCCCCC[n+]1cccc2c3ccccc3ccc21 CHEMBL1347071 AC50 70.79 nM
COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2C#N)cc1 CHEMBL523475 IC50 76.0 nM
CN1CCc2cc3c(cc2C(=O)Cc2cc4c(cc2C1)OCO4)OCO3 CHEMBL486179 Ki 78.0 nM
Cc1ccc(C[C@H](Cc2nc3ccccc3[nH]2)c2nc3ccccc3[nH]2)cc1 CHEMBL1526068 Potency 79.4 nM
COC(=O)C/C=C1\c2ccccc2C(OC)C1C CHEMBL1473190 Potency 79.4 nM
CN1Cc2c(ccc3c2OCO3)[C@@H]2[C@@H](O)Cc3cc4c(cc3[C@@H]21)OCO4 CHEMBL1394506 Potency 79.4 nM
O=C(NCCC[N+]1=CC=N[C@H]1c1ccccc1)N1CCCc2nc(-c3ccc(Br)cc3)ccc21 CHEMBL1472523 Potency 79.4 nM
COCCn1c(=O)c(-c2ccc(Cl)cc2)nc2cnc(N(C)C)nc21 CHEMBL1314956 Potency 79.4 nM
COc1ccccc1CNc1nc(-c2ccccc2OC)nc2ccccc12 CHEMBL1317066 Potency 79.4 nM
CCN(CC)CCO[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@H]2CC[C@]2(C)C(=O)CC[C@H]32)C1 CHEMBL1397169 Potency 79.4 nM
C[C@]12N[C@@H](Cc3ccccc31)c1ccccc12 CHEMBL467706 Potency 79.4 nM
O=C(O)C=Cc1ccc(Cn2ccnc2)cc1 CHEMBL3195727 Potency 79.4 nM
CNC(=O)Oc1ccc2c(c1)[C@@]1(C)CCN(C)[C@@H]1N2C CHEMBL1243269 Potency 79.4 nM
CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc(c43)[C@@H]2C1 CHEMBL1496514 Potency 79.4 nM
CS(=O)(=O)N1CCC2(CCCN(Cc3ccccc3)C2)CC1 CHEMBL1524577 Potency 79.4 nM
CN1CCc2ccccc2[C@@H]1Cc1ccccc1NC(=O)c1sc2ccccc2c1Cl CHEMBL1525179 Potency 79.4 nM
CCOc1cccc(NC(=O)CSc2nc(C)c3c(c2C#N)CCCC3)c1 CHEMBL1604887 AC50 79.43 nM
Fc1ccccc1CCNCc1cccc(Cl)c1Cl CHEMBL1303741 AC50 79.43 nM
COc1ccc(-c2cc(=O)oc3cc4occ(C)c4cc23)cc1 CHEMBL1453817 AC50 79.43 nM
Cc1cnnn1-c1ccc(C(=O)CCl)cc1 CHEMBL1419252 AC50 79.43 nM
COC(=O)[C@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL31410 Ki 80.0 nM
CC(C)(Cc1c[nH]c2ccc(O)cc12)NCC(O)COc1ccccc1C#N CHEMBL426596 IC50 80.0 nM
CC(=O)c1sc(NC(=O)N[C@@H]2CN(C(=O)C3CC3)CC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)nc1C CHEMBL402708 IC50 80.0 nM
COC(=O)N1CC[C@@H](CN2CCC[C@@H](Cc3ccc(F)cc3)C2)[C@H](NC(=O)Nc2nc(C)c(C(C)=O)s2)C1 CHEMBL249852 IC50 80.0 nM
CCC(NCCCC[C@@H](Cc1cc(C)c(F)c(C)c1)C(=O)NO)c1ccc(F)cc1 CHEMBL2010824 IC50 80.0 nM
Nc1ccccc1NC(=O)c1ccc(CNC2=N[C@@H](c3ccccc3)CS2)cc1 CHEMBL2407717 IC50 80.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3cnccc23)c2ccc(OC(F)(F)F)cc2O1 CHEMBL3326576 IC50 80.0 nM
CN(C)CCCOc1cccc(CNC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL4436040 IC50 80.0 nM
FC(F)(F)Oc1ccc([C@H]2C[C@@H](CN3CCCC3)N2Cc2ccccc2OC(F)(F)F)cc1 CHEMBL5409017 IC50 80.0 nM
N[C@H]1CC[C@@H](N(C[C@H]2Cc3ccccc3CN2)[C@H]2CCCc3cccnc32)CC1 CHEMBL4161850 IC50 81.0 nM
c1ccc2c(c1)CN[C@@H](CN(Cc1ccc(CNCc3ccncc3)cc1)[C@H]1CCCc3cccnc31)C2 CHEMBL4083122 IC50 84.0 nM
C/C(=C/CN)CN(C[C@H]1Cc2ccccc2CN1)[C@H]1CCCc2cccnc21 CHEMBL4164075 IC50 88.0 nM
CCNC(=O)c1ccc(C2=CC3(CCNCC3)Oc3ccccc32)cc1 CHEMBL551412 IC50 89.0 nM
CCOC(=O)CSc1nnc(Cc2ccccc2)n1-c1cccc(Cl)c1 CHEMBL1729853 AC50 89.13 nM
CCC(=O)Nc1ccccc1C(=O)OCC(=O)c1cccc2ccccc12 CHEMBL1561570 AC50 89.13 nM
Cc1cc(N2CCCCC2)nc(NCc2ccccc2)n1 CHEMBL601135 AC50 89.13 nM
Cc1ccccc1OCC(O)CNC(C)(C)Cc1cc2ccccc2n1C CHEMBL361365 IC50 90.0 nM
Cc1ccccc1-c1nc2ccc(Oc3ccc(F)cc3)cc2c(=O)n1C[C@H]1CCCN(C(C)C)C1 CHEMBL242564 IC50 90.0 nM
CCc1ccccc1O[C@@H]1c2ccccc2OC[C@@H]1CNC CHEMBL498481 IC50 90.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)cc2)N=C(c2ccccc2)N1 CHEMBL519680 IC50 90.0 nM
NCc1noc(-c2nn(Cc3ccccc3)c3ccccc23)n1 CHEMBL512079 IC50 90.0 nM
COc1ccc2[nH]c(SCc3ccc(Br)cc3)nc2c1 CHEMBL2018920 IC50 90.0 nM
CC1(C)CCC(NCCCCN(C[C@H]2Cc3ccccc3CN2)[C@H]2CCCc3cccnc32)CC1 CHEMBL4059462 IC50 90.0 nM
CCCOc1cccc(CNC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL4476761 IC50 90.0 nM
CCS(=O)(=O)c1ccc2c(c1)CN(C=O)C2C(=O)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4847761 IC50 90.0 nM
N[C@H]1CCN(c2c(-c3cc(F)cc(Cl)c3)cncc2-c2nc3c(F)cccc3[nH]2)C1 CHEMBL5176490 IC50 90.0 nM
NC1CN(c2cc(-c3ccsc3)ncn2)CC1c1cc(F)c(F)cc1F CHEMBL395426 IC50 98.0 nM