O=C(c1cccnc1-c1ccncn1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL5279173 IC50 1.0 nM
O=C(c1cc(Cl)ccc1-c1ccncc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL5288661 IC50 2.4 nM
Cc1ccc(-c2ccncc2)c(C(=O)N2CCC(O)(Cc3ccccc3)CC2)c1 CHEMBL5276973 IC50 2.7 nM
O=C(c1ccccc1-c1ccncn1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL5282804 IC50 4.3 nM
Cc1ccc(C(=O)N2CCC(O)(Cc3ccccc3)CC2)c(-c2ccncc2)c1 CHEMBL5271033 IC50 4.4 nM
COc1ccc(-c2ccncc2)c(C(=O)N2CCC(O)(Cc3ccccc3)CC2)c1 CHEMBL5269674 IC50 4.7 nM
Cc1ccc(-c2ccncc2C)c(C(=O)N2CCC(O)(Cc3ccccc3)CC2)c1 CHEMBL5289771 IC50 4.9 nM
O=C(c1cc(F)ccc1-c1ccncc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL5284673 IC50 6.1 nM
CN(C)C(=O)C1CCN(c2cncnc2-c2ccc(F)cc2)CC1 CHEMBL5093928 IC50 7.3 nM
O=C(c1cccnc1-c1ccncc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL4298172 IC50 7.4 nM
Cc1cccc(-c2ccncc2)c1C(=O)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL5275089 IC50 7.8 nM
O=C(c1ccccc1-c1ccncc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL5275183 IC50 7.9 nM
O=C(NC1CC1)C1CCN(c2cnccc2-c2ccccc2)CC1 CHEMBL4594072 IC50 8.1 nM
Cc1cnn(-c2ccncc2N2CCC(C(=O)N(C)C)CC2)c1 CHEMBL4532699 IC50 8.5 nM
CN(C)C(=O)C1CCN(c2cnccc2-n2cc(Br)cn2)CC1 CHEMBL4527933 IC50 9.5 nM
C[C@@H](c1ncncc1F)[C@](O)(Cn1cncn1)c1ccc(F)cc1F CHEMBL638 Ki 11.0 nM
CN(C)C(=O)C1CCN(c2cnccc2-n2cc(C3CC3)cn2)CC1 CHEMBL4538165 IC50 12.0 nM
Cc1cnc(-c2ccncc2N2CCC(C(=O)N(C)C)CC2)s1 CHEMBL5083867 IC50 12.0 nM
O=C(/C=C/c1ccc(O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1)NCCCNCCCCNC(=O)CCc1ccc(O)c(O)c1 CHEMBL5195220 Ki 12.89 nM
CCN(C)C(=O)C1CCN(c2cncnc2-c2ccccc2)CC1 CHEMBL5076011 IC50 14.0 nM
CN(C)C(=O)C1CCN(c2cncnc2-c2ccccc2)CC1 CHEMBL5082831 IC50 16.0 nM
Cc1ccc(-c2ccncc2)c(C(=O)N2CCC(Cc3ccccc3)C(O)C2)c1 CHEMBL5286208 IC50 16.0 nM
Cc1ccc(-c2ccncc2F)c(C(=O)N2CCC(O)(Cc3ccccc3)CC2)c1 CHEMBL5274224 IC50 17.0 nM
O=C(c1ccccc1-c1ccncc1)N1CCC(O)(Cc2ccccn2)CC1 CHEMBL5269081 IC50 21.0 nM
CN(C)C(=O)C1CCN(c2cnccc2-n2cc(Cl)cn2)CC1 CHEMBL4580834 IC50 24.0 nM
O=C(Nc1ccccc1)C1CCN(c2cncnc2-c2ccccc2)CC1 CHEMBL5087082 IC50 28.0 nM
O=C(c1ccccc1-c1ccncn1)N1CCC(O)(Cc2ccccn2)CC1 CHEMBL5272679 IC50 36.0 nM
O=C(NC1CC1)C1CCN(c2cncnc2-c2ccccc2)CC1 CHEMBL4561003 IC50 44.0 nM
CN(C)C(=O)C1CCN(c2cnccc2-n2cccn2)CC1 CHEMBL5083692 IC50 48.0 nM
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OS(=O)(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL1231592 Kd 50.0 nM
O=C(NC1CC1)N1CCN(c2cnccc2-c2ccccc2)CC1 CHEMBL4555625 IC50 52.0 nM
CCNC(=O)C1CCN(c2cncnc2-c2ccccc2)CC1 CHEMBL5094350 IC50 58.0 nM
Cc1ccccc1C1=NN(C(=O)c2ccncc2)C(C)(C)C1 CHEMBL5285548 IC50 60.0 nM
CN(C)C(=O)C1CCN(c2cnccc2-n2cc(C(F)(F)F)cn2)CC1 CHEMBL5082660 IC50 65.0 nM
CN(C)C(=O)C1CCN(c2cnccc2-c2ccccn2)CC1 CHEMBL5080231 IC50 68.0 nM
CNC(=O)C1CCN(c2cncnc2-c2ccccc2)CC1 CHEMBL5085981 IC50 72.0 nM
O=C(NC1CC1)c1ccc(-c2cnccc2-c2ccccc2)cc1 CHEMBL5074135 IC50 74.0 nM
COC1(Cc2ccccc2)CCN(C(=O)c2cc(C)ccc2-c2ccncc2)CC1 CHEMBL5282243 IC50 74.0 nM
Cc1ccc(-c2ccncc2)c(C(=O)N2CCN(Cc3ccccc3)C(=O)C2)c1 CHEMBL5267408 IC50 89.0 nM
Cc1ccc(-c2ccncc2)c(C(=O)N2CCN(Cc3ccccc3)CC2)c1 CHEMBL5288871 IC50 93.0 nM
O=C(c1cccnc1-c1ccncc1)N1CCC(O)(Cc2ccccn2)CC1 CHEMBL5269664 IC50 100.0 nM
O=C(/C=C/c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(O)c1)NCCCNCCCCNC(=O)CCc1ccc(O)c(O)c1 CHEMBL5186695 Ki 106.3 nM
Cc1ccc(-c2ccncc2)c(C(=O)N2CCC(Cc3ccccc3)CC2)c1 CHEMBL5288993 IC50 110.0 nM
Cc1cccc(C(=O)N2CCC(O)(Cc3ccccc3)CC2)c1-c1ccncc1 CHEMBL5275961 IC50 130.0 nM
O=C(NC1CC1)C1CCN(c2cnccc2-c2ccccn2)CC1 CHEMBL5086659 IC50 160.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)NCCCNCCCCNC(=O)CCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(O)c1 CHEMBL5206380 Ki 258.4 nM
O=C(c1ccncc1)N1N=C(c2ccccc2)CC1(O)C(F)(F)F CHEMBL5266978 IC50 350.0 nM
S=C(NC1CCCCC1)N1CCC(c2cnc[nH]2)CC1 CHEMBL260374 IC50 430.0 nM
CCC1(O)CCN(C(=O)c2cc(C)ccc2-c2ccncc2)CC1 CHEMBL5291094 IC50 540.0 nM
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL112570 Kd 670.0 nM
O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1 CHEMBL223228 Kd 800.0 nM
O=C(NC1CC1)N1CCC(c2cnccc2-c2ccccc2)CC1 CHEMBL5074319 IC50 950.0 nM