CCCCCCCCCCCC(C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O CHEMBL4476210 pIC50 0.2512 nM
CC(C)(C)OC(=O)N1CCN(C(=O)n2cc(-c3ccc(OC(F)(F)F)cc3)nn2)C(Cc2ccccc2)C1 CHEMBL4581240 pIC50 0.5012 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)C3(c4cccc(-c5cc(Cl)cc(Cl)c5)c4)CCC3)ccc2O1 CHEMBL3764017 IC50 0.6 nM
O=C(N1C[C@H](OCC2CC2)CC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3897587 pIC50 0.631 nM
O=C(N1CCCC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3954476 pIC50 0.7943 nM
O=C(N1CCCC[C@@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL3906477 pIC50 0.7943 nM
CO[C@@H]1CC[C@H](Cc2ccccc2)N(C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)C1 CHEMBL3913807 pIC50 0.7943 nM
O=C(N1CCC=C[C@@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4279328 pIC50 0.7943 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)C3(c4cccc(-c5cc(Cl)cc(Cl)c5)c4)CCCC3)ccc2O1 CHEMBL3765578 IC50 0.9 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O CHEMBL175247 IC50 1.0 nM
O=C(N1CCCCC1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3970032 pIC50 1.0 nM
C#CCO[C@@H]1CC[C@H](Cc2ccccc2)N(C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)C1 CHEMBL3895863 pIC50 1.259 nM
O=C(O)CN(c1cccc(-c2cccc(Cl)c2Cl)c1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3764876 IC50 2.4 nM
O=C(N1CCCCC1Cc1ccccc1)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL3964338 pIC50 2.512 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3cccc(-c4cc(Cl)cc(Cl)c4)c3)ccc2O1 CHEMBL3763826 IC50 3.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3ccc(-c4cc(Cl)cc(Cl)c4)cc3)ccc2O1 CHEMBL3765716 IC50 3.0 nM
O=C(O)CN(Cc1cccc(-c2cccc(Cl)c2Cl)c1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3763853 IC50 3.0 nM
COc1cccc(CC2CCCCN2C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)c1 CHEMBL3941507 pIC50 3.162 nM
Cc1ccc(-c2cnc3nc(C(=O)CCCCCc4ccccc4)oc3c2)cc1 CHEMBL4447844 pIC50 3.162 nM
O=C(CCCCCCCCc1ccccc1)c1nc2ncccc2o1 CHEMBL182199 pIC50 3.631 nM
O=C(O)CN(C1(c2cccc(-c3cc(Cl)cc(Cl)c3)c2)CCC1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL3763831 IC50 4.0 nM
COc1ccc(CC2CCCCN2C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)cc1 CHEMBL3903742 pIC50 5.012 nM
O=C(N1CCCCC1COc1ccc(F)cc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3921538 pIC50 5.012 nM
O=C(N1CCCCC1COc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3916842 pIC50 5.012 nM
O=C(O)CN(C1(c2ccc(-c3ccc(Cl)cc3Cl)cc2)CCC1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765421 IC50 6.0 nM
O=C(O)CN(C1(c2cccc(-c3ccc(Cl)cc3Cl)c2)CCC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1 CHEMBL3764093 IC50 6.0 nM
O=C(N1CCCCC1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL2144065 pIC50 6.31 nM
O=C(N1CCCCC1COc1ccc(F)cc1)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL3986579 pIC50 6.31 nM
CO[C@H]1CC[C@H](Cc2ccccc2)N(C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)C1 CHEMBL3922787 pIC50 7.943 nM
O=C(N1CCCCC1COc1ccccc1)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL3897762 pIC50 7.943 nM
O=C(O)CN(C1(c2ccc(-c3ccccc3OC(F)(F)F)cc2)CCC1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765022 IC50 8.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)C3(c4ccc(-c5cc(Cl)cc(Cl)c5)cc4)CCOC3)ccc2O1 CHEMBL3763430 IC50 8.0 nM
O=C(O)CN(C1(c2cccc(-c3cc(Cl)cc(Cl)c3)c2)CCC1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765158 IC50 11.0 nM
O=C(N1C[C@H](O)C=C[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3931744 pIC50 12.59 nM
COC(c1ccc(F)cc1)(c1ccc(F)cc1)c1cnn(C(=O)N2CCCCC2Cc2ccccc2)n1 CHEMBL3925845 pIC50 12.59 nM
O=C(N1C[C@H](O)C=C[C@@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4287766 pIC50 15.85 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc([N+](=O)[O-])cc2)nn1 CHEMBL4281906 pIC50 15.85 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(Br)cc2)nn1 CHEMBL4294845 pIC50 15.85 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](NC=O)C(C)CC CHEMBL521157 IC50 16.0 nM
O=C(O)CN(Cc1cccc(-c2cc(Cl)cc(Cl)c2)c1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765824 IC50 16.0 nM
O=C(O)CN(Cc1ccc(-c2ccccc2OC(F)(F)F)cc1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3764778 IC50 17.0 nM
O=C(O)CN(Cc1cccc(-c2ccccc2OC(F)(F)F)c1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3764377 IC50 17.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3ccc(Oc4ccccc4)cc3)ccc2O1 CHEMBL3319620 IC50 18.0 nM
C[C@@H](c1ccc(-c2ccc(Cl)cc2Cl)cc1)N(CC(=O)O)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765573 IC50 18.0 nM
C[C@H](c1ccc(-c2ccc(Cl)cc2Cl)cc1)N(CC(=O)O)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765497 IC50 19.0 nM
O=C(N1C[C@@H](OCC2CC2)CC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3967137 pIC50 19.95 nM
O=C(N1C[C@@H](O)C=C[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3904310 pIC50 19.95 nM
O=C(N1C[C@H](O)CC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3912754 pIC50 19.95 nM
CCC1CCCCN1C(=O)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL3966016 pIC50 19.95 nM
O=C(N1CCCCC1Cc1ccccc1)n1cc(C(O)(c2ccccc2)c2ccccc2)nn1 CHEMBL3974512 pIC50 25.12 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4281842 pIC50 25.12 nM
O=C(N1C[C@H](O)C=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4289572 pIC50 25.12 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(Oc3ccccc3)cc2)nn1 CHEMBL4284689 pIC50 25.12 nM
CCCCCCCC/C=C\CCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL35925 pIC50 26.3 nM
O=C(O)CN(Cc1ccc(-c2ccc(Cl)cc2Cl)cc1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765546 IC50 30.0 nM
CCCCCCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL257307 pIC50 30.9 nM
O=C(N1C[C@@H](O)C=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4277989 pIC50 31.62 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](NC=O)C(C)C CHEMBL457232 IC50 35.0 nM
O=C(CCCCCc1ccccc1)c1nc2ncccc2o1 CHEMBL175854 pIC50 37.15 nM
O=C(N1CCCC[C@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL3934441 pIC50 39.81 nM
O=C(O)CN(C1(c2ccc(-c3ccccc3OC(F)(F)F)cc2)CC1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3764349 IC50 40.0 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](C)NC=O CHEMBL516323 IC50 43.0 nM
N#Cc1ccc(S(=O)(=O)N(CC(=O)O)C2(c3cccc(-c4cc(Cl)cc(Cl)c4)c3)CCC2)cc1 CHEMBL3765562 IC50 45.0 nM
O=C(CCCCCCCc1ccccc1)c1nc2ncccc2o1 CHEMBL179760 pIC50 46.77 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3cccc(-c4ccccc4)c3)ccc2O1 CHEMBL3764044 IC50 55.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3cccc(Oc4ccccc4)c3)ccc2O1 CHEMBL3319619 IC50 56.0 nM
O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C1CCCCC1 CHEMBL158897 IC50 60.0 nM
O=C(O)CN(C1(c2cccc(-c3cc(Cl)cc(Cl)c3)c2)CCC1)S(=O)(=O)c1cccc(Cl)c1 CHEMBL3763964 IC50 60.0 nM
CCC1CCCCN1C(=O)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL1891894 pIC50 63.1 nM
CCCCCCCCCCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL1812706 pIC50 64.57 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3ccc(Oc4ccc(C(F)(F)F)cn4)cc3)ccc2O1 CHEMBL3319622 IC50 65.0 nM
O=C(O)CN(Cc1ccc(Oc2ccccc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL3319625 IC50 66.0 nM
CCCCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL1812708 pIC50 74.13 nM
CCCCCCCCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL1812707 pIC50 74.13 nM
O=C(N1CCCC[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4279884 pIC50 79.43 nM
O=C(N1CCC=C[C@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4291201 pIC50 79.43 nM
O=C(O)CN(Cc1ccc(-c2ccccc2)cc1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3765634 IC50 80.0 nM
O=C(O)CN(C1(c2cccc(-c3cc(Cl)cc(Cl)c3)c2)CCC1)S(=O)(=O)c1ccccc1 CHEMBL3765750 IC50 80.0 nM
O=C(CCCCCc1ccccc1)c1nc2ccc([N+](=O)[O-])cc2o1 CHEMBL3753830 pIC50 87.1 nM
O=C(O)CN(Cc1cccc(Oc2ccccc2)c1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL3319623 IC50 91.0 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H]1CCC(=O)N1 CHEMBL484393 IC50 100.0 nM
O=C(N1CCCCC1Cc1ccccc1)n1ncc(C(O)(C2CCCCC2)C2CCCCC2)n1 CHEMBL3929394 pIC50 100.0 nM
O=C(CCCCCc1ccccc1)c1nc2c(F)cccc2o1 CHEMBL3754098 pIC50 117.49 nM
CC(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 CHEMBL461543 pIC50 123.03 nM
O=C(CCCCCCc1ccccc1)c1nc(C(=O)C(F)(F)F)co1 CHEMBL461364 pIC50 123.03 nM
COc1ccccc1-c1ccc(-c2cn(C(=O)N3CCCCC3Cc3ccccc3)nn2)cc1 CHEMBL2136920 pIC50 125.89 nM
CN(C)C(=O)n1nnnc1CNC(=O)c1ccc(N=[N+]=[N-])c(I)c1 CHEMBL486037 IC50 130.0 nM
O=C(O)CN(C1(c2ccc(-c3ccc(Cl)cc3Cl)cc2)CC1)S(=O)(=O)c1ccc(OC(F)F)cc1 CHEMBL3764007 IC50 130.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3cccc(Oc4ccc(C(F)(F)F)cn4)c3)ccc2O1 CHEMBL3319621 IC50 143.0 nM
O=C(N1CCCCC1Cc1ccccc1)n1ncc(C(O)(c2ccccn2)c2ccccn2)n1 CHEMBL3945819 pIC50 158.49 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccccc2)nn1 CHEMBL4288486 pIC50 158.49 nM
CCCCCCCC/C=C\CCCCCCCC(=O)OC(COC)COP(C)(=O)F CHEMBL473511 IC50(app) 160.0 nM
COc1cccc(S(=O)(=O)N(CC(=O)O)C2(c3cccc(-c4cc(Cl)cc(Cl)c4)c3)CCC2)c1 CHEMBL3764430 IC50 161.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3ccccc3Oc3ccccc3)ccc2O1 CHEMBL3319618 IC50 185.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)c1nc2ccccc2[nH]1 CHEMBL3753992 pIC50 194.98 nM
CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCc1ccccc1 CHEMBL453043 IC50 200.0 nM
O=C(CCCCc1ccccc1)c1nc2ncccc2o1 CHEMBL464186 pIC50 204.17 nM
O=C(CCCCCc1ccccc1)c1nc2cnccc2o1 CHEMBL3753016 pIC50 204.17 nM
O=C(CCCCCCc1ccccc1)c1nc(C(F)(F)F)co1 CHEMBL461544 pIC50 213.8 nM
O=C(O)CN(Cc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL3319629 IC50 302.0 nM
CN(C)C(=O)n1nnnc1CNC(=O)c1cccc(-c2ccccc2)c1 CHEMBL519874 IC50 340.0 nM
CS(=O)(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 CHEMBL3753217 pIC50 389.05 nM
CC(O)(c1ccccc1)c1cnn(C(=O)N2CCCCC2Cc2ccccc2)n1 CHEMBL3907846 pIC50 398.11 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](NC(C)=O)C(C)CC CHEMBL484215 IC50 430.0 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](NC(C)=O)C(C)C CHEMBL521467 IC50 460.0 nM
CC(C)(C)C(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 CHEMBL3752580 pIC50 478.63 nM
CN(C)C(=O)n1nnc(CCCc2ccccc2)n1 CHEMBL505359 IC50 500.0 nM
CN(C)C(=O)n1nnc(Cc2ccc(-c3ccccc3)cc2)n1 CHEMBL485841 IC50 510.0 nM
O=C(O)CN(C1(c2cccc(-c3cc(Cl)cc(Cl)c3)c2)CCC1)S(=O)(=O)c1ccccc1Cl CHEMBL3763708 IC50 510.0 nM
CC1(C)CCc2cc(S(=O)(=O)N(CCN)Cc3ccc(Oc4ccccc4)cc3)ccc2O1 CHEMBL3319637 IC50 512.0 nM
O=C(CCCCCCc1ccccc1)c1nc2ncccc2o1 CHEMBL367966 pIC50 524.81 nM
C=CCCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL3754151 pIC50 549.54 nM
CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCCc1ccccc1 CHEMBL486039 IC50 570.0 nM
N#Cc1coc(C(=O)CCCCCCc2ccccc2)n1 CHEMBL462423 pIC50 575.44 nM
CN(C)C(=O)n1nnc(CCc2ccccc2)n1 CHEMBL504374 IC50 600.0 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)CCNC=O CHEMBL514886 IC50 600.0 nM
CCCCCCCC(=O)c1nc2ncccc2o1 CHEMBL257305 pIC50 630.96 nM
COC(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 CHEMBL461539 pIC50 630.96 nM
CCCCCCC/C=C\CCCCCCCC(=O)OC(COC(C)C)COP(C)(=O)F CHEMBL4558419 IC50 690.0 nM
O=C(O)CN(Cc1ccc(Oc2ccccc2)cc1)S(=O)(=O)c1c(Cl)cccc1Cl CHEMBL3319626 IC50 695.0 nM
O=C(CCCCCc1ccccc1)c1nc2ccc(F)cc2o1 CHEMBL3753292 pIC50 707.95 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)CNC(C)=O CHEMBL458828 IC50 800.0 nM
O=C(CCCCCc1ccccc1)c1nc2cc([N+](=O)[O-])ccc2o1 CHEMBL3753795 pIC50 891.25 nM
O=C(CCCCCCc1ccccc1)c1nc(-c2ccco2)no1 CHEMBL469199 pIC50 933.25 nM