O=c1[nH]nc(CCc2ccc(-c3ccccc3)cc2)cc1O CHEMBL3904227 IC50 1.2 nM
O=c1[nH]nc(CCc2cccc(F)c2)cc1O CHEMBL2338797 IC50 1.4 nM
O=C(O)c1cc2sccc2[nH]1 CHEMBL507614 IC50 1.4 nM
O=c1[nH]nc(CCc2cc(F)cc(F)c2)cc1O CHEMBL2338803 IC50 1.5 nM
Oc1noc2cc(Cl)c(Cl)cc12 CHEMBL2375520 Ki 1.7 nM
O=c1[nH]c2ncccc2cc1O CHEMBL468495 Kd 2.0 nM
O=c1[nH]nc(CCc2ccccc2F)cc1O CHEMBL2338795 IC50 2.0 nM
COc1cccc(CCc2cc(O)c(=O)[nH]n2)c1 CHEMBL2338799 IC50 2.1 nM
O=c1[nH]nc(CCc2cccc(CO)c2)cc1O CHEMBL3965781 IC50 2.1 nM
O=c1cc(COc2ccccc2)[nH]nc1O CHEMBL2338794 IC50 2.2 nM
O=c1[nH]nc(CCc2ccc(F)cc2F)cc1O CHEMBL3925924 IC50 2.2 nM
O=c1[nH]nc(CCc2cccc3ccccc23)cc1O CHEMBL3941866 IC50 2.3 nM
O=c1cc(COc2cccc(F)c2)[nH]nc1O CHEMBL3899415 IC50 2.3 nM
O=c1[nH]nc(CCc2ccccc2)cc1O CHEMBL2338786 IC50 2.4 nM
O=c1[nH]nc(CCc2cccc(C(F)(F)F)c2)cc1O CHEMBL2338798 IC50 2.4 nM
O=c1cc(/C=C/c2ccccc2)[nH]nc1O CHEMBL3900453 IC50 2.4 nM
O=c1[nH]c2cccc(Cl)c2cc1O CHEMBL495187 Kd 2.5 nM
Cc1cccc(CCc2cc(O)c(=O)[nH]n2)c1 CHEMBL3985690 IC50 2.5 nM
O=c1[nH]nc(CCCCc2ccccc2)cc1O CHEMBL3913880 IC50 2.5 nM
O=c1[nH]nc(CCc2ccc(Cl)cc2)cc1O CHEMBL2338790 IC50 2.7 nM
COc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1 CHEMBL2338802 IC50 2.9 nM
O=c1[nH]nc(CCc2ccc(CO)cc2)cc1O CHEMBL3964892 IC50 2.9 nM
O=c1cc(COc2ccc(F)cc2)[nH]nc1O CHEMBL3950593 IC50 2.9 nM
O=c1[nH]c2ncc(F)c(Cl)c2cc1O CHEMBL467661 IC50 3.0 nM
O=c1[nH]c2c(F)cccc2cc1O CHEMBL494235 IC50 3.0 nM
O=C(O)c1cc2occc2[nH]1 CHEMBL492591 Kd 3.1 nM
O=c1[nH]nc(CCc2ccc(F)cc2)cc1O CHEMBL2338800 IC50 3.1 nM
Cc1ccccc1CCc1cc(O)c(=O)[nH]n1 CHEMBL3948236 IC50 3.3 nM
O=c1cc(COc2ccccc2F)[nH]nc1O CHEMBL3914284 IC50 3.5 nM
O=c1[nH]nc(SCc2ccc(Cl)cc2)cc1O CHEMBL3930320 IC50 3.7 nM
O=c1[nH]cc(CCc2ccccc2)cc1O CHEMBL2338785 IC50 3.9 nM
O=c1[nH]c2ccccc2cc1O CHEMBL146227 IC50 4.0 nM
O=c1[nH]c2ccc(F)c(Cl)c2cc1O CHEMBL467660 Kd 4.6 nM
O=c1cc(CCC2CCCCC2)[nH]nc1O CHEMBL2338789 IC50 4.7 nM
CC(c1ccccc1)c1cc(O)c(=O)[nH]n1 CHEMBL2338787 IC50 4.9 nM
O=c1cc(CSc2ccc(CO)cc2)[nH]nc1O CHEMBL3889972 IC50 5.2 nM
Cc1cc(CCc2cc(O)c(=O)[nH]n2)ccc1F CHEMBL3905105 IC50 6.0 nM
Cc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1 CHEMBL3914258 IC50 6.1 nM
CC(C)(C)c1ccc(CCc2cc(O)c(=O)[nH]n2)cc1 CHEMBL3902215 IC50 6.6 nM
CCCCc1cc(O)c(=O)[nH]n1 CHEMBL3962430 IC50 6.9 nM
O=C(O)c1cc(CCc2ccc(Cl)cc2)c[nH]1 CHEMBL453239 Ki 7.2 nM
CCc1cccc2[nH]c(=O)c(O)cc12 CHEMBL464841 IC50 8.0 nM
O=c1[nH]c2cccc(F)c2cc1O CHEMBL495186 IC50 8.0 nM
O=c1[nH]cc([C@@H]2COc3cc(COCc4cccc(F)c4)ccc3S2)[nH]c1=O CHEMBL5184138 IC50 8.0 nM
O=c1[nH]nc(CCCCO)cc1O CHEMBL3976562 IC50 8.1 nM
O=c1[nH]nc(CCc2ccc(C#CC(F)F)cc2)cc1O CHEMBL4107441 IC50 8.1 nM
O=c1[nH]nc(CCc2ccccc2C(F)(F)F)cc1O CHEMBL2338796 IC50 8.4 nM
O=c1[nH]nc(CCc2cccc(Cl)c2)cc1O CHEMBL3974794 IC50 8.4 nM
O=c1[nH]c2ccc(F)cc2cc1O CHEMBL509045 IC50 9.0 nM
C[C@@]1(c2c[nH]c(=O)c(=O)[nH]2)COc2cc(C(F)(F)F)ccc2S1 CHEMBL5204161 IC50 9.0 nM
C[C@@]1(c2c[nH]c(=O)c(=O)[nH]2)COc2cc(Cl)ccc2S1 CHEMBL5188193 IC50 9.0 nM
O=c1[nH]c2cc(F)ccc2cc1O CHEMBL443399 IC50 10.0 nM
O=c1[nH]nc(CCc2ccc(F)c(F)c2)cc1O CHEMBL3921356 IC50 10.0 nM
O=c1[nH]nc(CCc2cc(F)c(C(F)(F)F)c(F)c2)cc1O CHEMBL3978036 IC50 10.0 nM
O=c1[nH]c(=O)n(O)cc1CCc1ccc(Cl)cc1 CHEMBL5173250 IC50 11.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)cc2)cc1O CHEMBL2338801 IC50 12.0 nM
O=c1[nH]nc(Cc2ccccc2)cc1O CHEMBL3907451 IC50 12.0 nM
O=c1[nH]nc(Cc2ccc(Cl)cc2)cc1O CHEMBL3937708 IC50 12.0 nM
Cc1cccc(Cc2cc(O)c(=O)[nH]n2)c1 CHEMBL3890910 IC50 12.0 nM
Cc1cc(C(F)(F)F)ccc1CCc1cc(O)c(=O)[nH]n1 CHEMBL3948886 IC50 12.0 nM
Oc1noc2cc(Cl)ccc12 CHEMBL445990 Kd 13.0 nM
COc1cc(CCc2cc(O)c(=O)[nH]n2)cc(OC)c1 CHEMBL2338805 IC50 13.0 nM
O=c1[nH]nc(CCCc2ccccc2)cc1O CHEMBL2338788 IC50 13.0 nM
O=c1oc2ccccc2cc1O CHEMBL150372 Ki 13.0 nM
COc1cc(CO)cc(CCc2cc(O)c(=O)[nH]n2)c1 CHEMBL3920414 IC50 13.0 nM
N#Cc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1 CHEMBL3969619 IC50 13.0 nM
O=c1[nH]nc(Cc2cccc(Cl)c2)cc1O CHEMBL3959707 IC50 13.0 nM
Cc1cc(CCc2cc(O)c(=O)[nH]n2)ccc1C(F)(F)F CHEMBL3965028 IC50 13.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)c(Cl)c2)cc1O CHEMBL3986233 IC50 13.0 nM
O=c1[nH]cc([C@@H]2COc3cc(C(F)F)ccc3S2)[nH]c1=O CHEMBL5179642 IC50 13.0 nM
O=c1[nH]nc(CCc2cccc(C(F)F)c2)cc1O CHEMBL3982802 IC50 14.0 nM
Cc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1F CHEMBL3929576 IC50 14.0 nM
O=c1[nH]nc(CCc2c(F)cccc2Cl)cc1O CHEMBL3966850 IC50 14.0 nM
O=c1[nH]nc(Cc2ccc(F)cc2)cc1O CHEMBL3946543 IC50 15.0 nM
O=c1[nH]nc(Cc2ccccc2F)cc1O CHEMBL3967423 IC50 15.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)cc2F)cc1O CHEMBL3931005 IC50 15.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)c(C(F)(F)F)c2)cc1O CHEMBL3893956 IC50 15.0 nM
Cc1cccc2[nH]c(=O)c(O)cc12 CHEMBL495023 IC50 16.0 nM
O=c1[nH]nc(CCC2CCCC2)cc1O CHEMBL3968355 IC50 16.0 nM
O=c1[nH]nc(CCc2cccc(OC(F)F)c2)cc1O CHEMBL3897961 IC50 16.0 nM
O=c1[nH]nc(CCc2ccc(OC(F)F)cc2)cc1O CHEMBL3892561 IC50 18.0 nM
O=c1[nH]nc(Cc2cccc(F)c2)cc1O CHEMBL3983879 IC50 18.0 nM
O=c1[nH]nc(CCc2c(F)cccc2F)cc1O CHEMBL3942533 IC50 19.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)cc2Cl)cc1O CHEMBL3906530 IC50 19.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)c(F)c2)cc1O CHEMBL3942392 IC50 19.0 nM
O=c1[nH]nc(CCc2ccccc2Cl)cc1O CHEMBL3958088 IC50 20.0 nM
O=c1[nH]nc(CCc2ccc(OC(F)(F)F)cc2)cc1O CHEMBL3969148 IC50 20.0 nM
CN(CC1CCCCC1)c1cc(O)c(=O)[nH]n1 CHEMBL3932199 IC50 20.0 nM
N#Cc1ccc2c(c1)OC[C@@H](c1c[nH]c(=O)c(=O)[nH]1)S2 CHEMBL5186374 IC50 20.0 nM
C[C@@]1(c2c[nH]c(=O)c(=O)[nH]2)COc2cc(C#N)ccc2S1 CHEMBL5178413 IC50 20.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)cn2)cc1O CHEMBL3906910 IC50 21.0 nM
O=c1[nH]nc(C2(c3ccccc3)CC2)cc1O CHEMBL3898429 IC50 21.0 nM
O=c1[nH]cc([C@@H]2COc3cc(Cl)ccc3S2)[nH]c1=O CHEMBL5179643 IC50 21.0 nM
O=c1[nH]nc(CCc2cccc(OC(F)(F)F)c2)cc1O CHEMBL3928039 IC50 22.0 nM
O=c1[nH]nc(Cc2ccccc2Cl)cc1O CHEMBL3958627 IC50 22.0 nM
O=c1[nH]nc(CCc2cncc(C(F)(F)F)c2)cc1O CHEMBL3908129 IC50 23.0 nM
O=c1[nH]nc(C2(c3ccc(F)cc3)CC2)cc1O CHEMBL3951636 IC50 23.0 nM
O=c1[nH]nc(Cc2cccc(C(F)(F)F)c2)cc1O CHEMBL3965884 IC50 23.0 nM
O=c1[nH]cc(C2COc3cc(C(F)(F)F)ccc3S2)[nH]c1=O CHEMBL5196542 IC50 25.0 nM
CS(=O)(=O)c1ccc2c(c1)OC[C@@H](c1c[nH]c(=O)c(=O)[nH]1)S2 CHEMBL5174518 IC50 25.0 nM
CC(c1ccc(F)cc1)c1cc(O)c(=O)[nH]n1 CHEMBL3977465 IC50 26.0 nM
O=c1[nH]nc(Cc2c(F)cccc2Cl)cc1O CHEMBL3975855 IC50 26.0 nM
Cc1ccc(Cc2cc(O)c(=O)[nH]n2)cc1 CHEMBL3896184 IC50 26.0 nM
O=c1[nH]c(=O)n(O)cc1CCc1ccccc1 CHEMBL5204839 IC50 28.0 nM
Cc1ccc(CSc2c[nH]c(=O)c(O)c2)cc1 CHEMBL3905206 IC50 29.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)cc2C(F)(F)F)cc1O CHEMBL3962904 IC50 29.0 nM
O=c1[nH]nc(SCc2ccc3cc(F)ccc3c2)nc1O CHEMBL3786955 IC50 30.0 nM
O=c1[nH]nc(SCc2ccc(Cl)cc2)nc1O CHEMBL3787162 IC50 30.0 nM
O=c1[nH]nc(CCc2ccc(C(F)(F)F)nc2)cc1O CHEMBL3893358 IC50 30.0 nM
O=c1[nH]nc(CCC2CCOCC2)cc1O CHEMBL3951265 IC50 30.0 nM
O=c1[nH]c2ccncc2cc1O CHEMBL468496 IC50 32.0 nM
O=c1[nH]c2c(Cl)cccc2cc1O CHEMBL446244 IC50 33.0 nM
O=c1[nH]cc(SCc2ccc(Cl)cc2)cc1O CHEMBL3894259 IC50 35.0 nM
O=C(O)c1csc(Cl)c1 CHEMBL4287507 IC50 36.0 nM
Cc1cccc2cc(O)c(=O)[nH]c12 CHEMBL451958 IC50 38.0 nM
O=c1[nH]c(=O)n(CCc2ccc(Cl)cc2)nc1O CHEMBL3613929 IC50 40.0 nM
O=c1[nH]nc(CCC2CC2)cc1O CHEMBL3893760 IC50 41.0 nM
CC(c1cccc(C(F)(F)F)c1)c1cc(O)c(=O)[nH]n1 CHEMBL3960349 IC50 41.0 nM
N#Cc1ccc(CSc2c[nH]c(=O)c(=O)[nH]2)cc1 CHEMBL5180296 IC50 43.0 nM
O=c1[nH]cc(CCC2CCCCC2)cc1O CHEMBL3926403 IC50 44.0 nM
O=c1[nH]cc(SCc2ccc(F)c(F)c2)cc1O CHEMBL3977283 IC50 45.0 nM
COc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1OC CHEMBL3952869 IC50 45.0 nM
N#Cc1ccc(SCc2c[nH]c(=O)c(=O)[nH]2)cc1F CHEMBL5184060 IC50 46.0 nM
O=c1[nH]cc(Cl)cc1O CHEMBL2338783 IC50 47.0 nM
O=c1[nH]cc(SCc2ccc(F)cc2)cc1O CHEMBL3971034 IC50 47.0 nM
O=c1[nH]c(=O)n(Cc2cccc3ccccc23)nc1O CHEMBL3613921 IC50 50.0 nM
O=c1[nH]c(=O)n(CCc2ccc(F)cc2)nc1O CHEMBL3613932 IC50 50.0 nM
O=c1[nH]c(=O)n(CCc2ccc(-c3ccccc3)cc2)nc1O CHEMBL3613946 IC50 50.0 nM
O=c1[nH]c(=S)n(CCc2ccccc2)nc1O CHEMBL3613951 IC50 50.0 nM
O=c1[nH]nc(SCc2ccc(I)cc2)nc1O CHEMBL3786099 IC50 50.0 nM
O=c1[nH]nc(SCc2ccc(Cl)c(Cl)c2)nc1O CHEMBL3785180 IC50 50.0 nM
C[C@@]1(c2c[nH]c(=O)c(=O)[nH]2)COc2cc(S(C)(=O)=O)ccc2S1 CHEMBL5179598 IC50 51.0 nM
Cc1ccc(CCc2c[nH]c(=O)c(O)c2)cc1 CHEMBL3908508 IC50 52.0 nM
COC1CCC(CCc2cc(O)c(=O)[nH]n2)CC1 CHEMBL3912913 IC50 52.0 nM
N#Cc1ccc(CSc2c[nH]c(=O)c(=O)[nH]2)cc1F CHEMBL5208196 IC50 54.0 nM
O=c1[nH]cc(SCc2cccc(Cl)c2)cc1O CHEMBL3946312 IC50 55.0 nM
O=c1[nH]nc(CCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1O CHEMBL2338804 IC50 57.0 nM
O=c1[nH]c(=O)n(CCc2cccc(Cl)c2)nc1O CHEMBL3613928 IC50 60.0 nM
O=c1[nH]c(=O)n(CCc2cccc(F)c2)nc1O CHEMBL3613931 IC50 60.0 nM
O=c1[nH]nc(SCc2ccc3c(c2)OCO3)nc1O CHEMBL3785719 IC50 60.0 nM
O=c1[nH]nc(CCc2ccccc2)nc1O CHEMBL3786114 IC50 60.0 nM
O=c1[nH]cc(CCc2ccc(F)cc2)cc1O CHEMBL3978887 IC50 61.0 nM
O=c1[nH]nc(C2(c3ccc(C(F)(F)F)cc3)CC2)cc1O CHEMBL3928108 IC50 61.0 nM
Cc1c(F)ccc2c1[nH]c(=O)n2O CHEMBL2152731 IC50 70.0 nM
O=c1[nH]c(=O)n(CCc2ccccc2)nc1O CHEMBL3613918 IC50 70.0 nM
Cc1cccc(CCn2nc(O)c(=O)[nH]c2=O)c1 CHEMBL3613934 IC50 70.0 nM
O=c1[nH]nc(Cc2ccccc2)nc1O CHEMBL3786396 IC50 70.0 nM
O=c1[nH]cc(SCc2ccc(C(F)F)cc2)[nH]c1=O CHEMBL5188286 IC50 70.0 nM
O=c1[nH]cc(CSc2ccc(C(F)F)cc2)[nH]c1=O CHEMBL5191702 IC50 72.0 nM
CCc1ccc(CSc2c[nH]c(=O)c(O)c2)cc1 CHEMBL3892689 IC50 79.0 nM
O=c1[nH]c2c(F)cc(F)cc2n1O CHEMBL2152734 IC50 80.0 nM
O=c1[nH]c(=O)n(CCc2ccccc2F)nc1O CHEMBL3613930 IC50 80.0 nM
Cc1ccccc1CCn1nc(O)c(=O)[nH]c1=O CHEMBL3613933 IC50 80.0 nM
O=c1[nH]c(=O)n(CCc2ccc(C(F)(F)F)cc2)nc1O CHEMBL3613937 IC50 80.0 nM
O=c1[nH]c(=O)n(CCc2ccc(Oc3ccccc3)cc2)nc1O CHEMBL3613945 IC50 80.0 nM
O=c1[nH]c(=O)n(CCc2ccccc2)cc1O CHEMBL3613952 IC50 80.0 nM
O=c1[nH]cc(CSc2ccc(S(F)(F)(F)(F)F)cc2)[nH]c1=O CHEMBL5183719 IC50 80.0 nM
CS(=O)(=O)c1ccc(SCc2c[nH]c(=O)c(=O)[nH]2)cc1 CHEMBL5179752 IC50 82.0 nM
COc1ccc(CSc2c[nH]c(=O)c(O)c2)cn1 CHEMBL3922910 IC50 83.0 nM
O=c1[nH]cc(CSc2cnc3cc(Cl)ccc3c2)[nH]c1=O CHEMBL5201918 IC50 87.0 nM
Cc1ccc(CCn2nc(O)c(=O)[nH]c2=O)cc1 CHEMBL3613935 IC50 90.0 nM
O=c1[nH]c(=O)n(CCc2ccccc2O)nc1O CHEMBL3613941 IC50 90.0 nM
O=c1[nH]nc(SCc2ccc(-c3ccccc3)cc2)nc1O CHEMBL3785277 IC50 90.0 nM
O=C(O)c1cc(Cl)c(Cl)s1 CHEMBL4285389 IC50 90.0 nM
CS(=O)(=O)c1ccc(CSc2c[nH]c(=O)c(=O)[nH]2)cc1 CHEMBL5192292 IC50 90.0 nM
O=c1[nH]cc(SCc2ccc(C(F)(F)F)cc2)[nH]c1=O CHEMBL5173262 IC50 91.0 nM
O=c1[nH]cc(CSc2ccc(C(F)(F)F)cc2)[nH]c1=O CHEMBL5178658 IC50 92.0 nM
CC1(c2c[nH]c(=O)c(=O)[nH]2)COc2ccccc2S1 CHEMBL5189921 IC50 93.0 nM
O=c1[nH]cc([C@@H]2COc3cc(F)ccc3S2)[nH]c1=O CHEMBL5202977 IC50 94.0 nM
O=c1[nH]cc(SCc2ccc(S(F)(F)(F)(F)F)cc2)[nH]c1=O CHEMBL5176574 IC50 97.0 nM
N#Cc1ccc(SCc2c[nH]c(=O)c(=O)[nH]2)cc1Cl CHEMBL5190430 IC50 98.0 nM
O=c1[nH]nc(CC2CCCCC2)cc1O CHEMBL3970755 IC50 99.0 nM
O=c1[nH]c2cc(Cl)ccc2cc1O CHEMBL452361 IC50 100.0 nM
O=c1[nH]c2c(F)cccc2n1O CHEMBL2152721 IC50 100.0 nM
COc1cccc2c1[nH]c(=O)n2O CHEMBL2152724 IC50 100.0 nM
O=c1cc(CSc2ccc(Cl)c(Cl)c2)occ1O CHEMBL2397821 IC50 100.0 nM
O=c1[nH]c(=O)n(CCc2cccc3ccccc23)nc1O CHEMBL3613922 IC50 100.0 nM
O=c1[nH]c(=O)n(CCc2ccccc2Cl)nc1O CHEMBL3613927 IC50 100.0 nM
O=c1[nH]c(=O)n(CCc2cccc(C(F)(F)F)c2)nc1O CHEMBL3613936 IC50 100.0 nM
O=c1[nH]nc(SCc2ccccc2)nc1O CHEMBL3786248 IC50 100.0 nM
O=c1[nH]cc(SCc2ccncc2)cc1O CHEMBL3982073 IC50 100.0 nM
O=c1[nH]c(=O)n(CCc2ccc(O)cc2)nc1O CHEMBL3613943 IC50 110.0 nM
O=c1[nH]nc(/C=C/c2ccc(Cl)cc2)cc1O CHEMBL2338791 IC50 120.0 nM
COc1cccc(CCn2nc(O)c(=O)[nH]c2=O)c1 CHEMBL3613939 IC50 120.0 nM
COc1ccc(CCn2nc(O)c(=O)[nH]c2=O)cc1 CHEMBL3613940 IC50 120.0 nM
Oc1n[nH]c2cc(F)ccc12 CHEMBL4225929 IC50 120.0 nM
O=c1[nH]c2ccsc2[nH]c1=O CHEMBL5194500 IC50 120.0 nM
O=c1[nH]c2cccnc2cc1O CHEMBL447057 IC50 128.0 nM
COc1ccc(CSc2c[nH]c(=O)c(O)c2)cc1 CHEMBL3926648 IC50 130.0 nM
O=c1[nH]cc(CCc2cccc(F)c2)cc1O CHEMBL3917465 IC50 130.0 nM
O=c1[nH]cc(SCc2cccc(F)c2)cc1O CHEMBL3917689 IC50 130.0 nM
CN(Cc1ccc(F)cc1)c1cc(O)c(=O)[nH]n1 CHEMBL3975337 IC50 130.0 nM
O=c1[nH]cc(CSc2ccc(Cl)cc2)[nH]c1=O CHEMBL5176256 IC50 130.0 nM
Cc1c[nH]c(=O)c(O)c1 CHEMBL2338784 IC50 140.0 nM
Oc1n[nH]c2cc(Cl)ccc12 CHEMBL4224785 IC50 150.0 nM
O=c1[nH]cc(SCc2ccc(Cl)cc2)[nH]c1=O CHEMBL5185870 IC50 150.0 nM
O=c1[nH]c2ccc(Cl)cc2cc1O CHEMBL463562 IC50 155.0 nM
O=c1[nH]c(=O)n(CCc2cccc(O)c2)nc1O CHEMBL3613942 IC50 160.0 nM
O=c1[nH]cc(SCc2ccc(C(F)(F)F)nc2)cc1O CHEMBL3922993 IC50 160.0 nM
O=c1[nH]cc(CCc2ccccc2F)cc1O CHEMBL3983751 IC50 170.0 nM
N#Cc1ccc(CCc2c[nH]c(=O)c(=O)[nH]2)cc1F CHEMBL5174605 IC50 180.0 nM
O=C(O)c1cc2occ(CCc3ccccc3)c2[nH]1 CHEMBL2375519 Ki 190.0 nM
O=c1[nH]cc(SCc2ccccc2)cc1O CHEMBL3932148 IC50 190.0 nM
O=c1[nH]cc(SCc2cccc(C(F)(F)F)c2)cc1O CHEMBL3919741 IC50 190.0 nM
O=c1[nH]cc(CCc2cccc(Cl)c2)[nH]c1=O CHEMBL5176152 IC50 190.0 nM
Cc1ccc2cc(O)c(=O)[nH]c2c1 CHEMBL502372 IC50 197.0 nM
Cc1cccc2c1[nH]c(=O)n2O CHEMBL2152722 IC50 200.0 nM
O=c1cc(CSc2ccc(Cl)cc2)occ1O CHEMBL2397748 IC50 200.0 nM
O=c1cc(CSc2ccccc2)occ1O CHEMBL2158320 IC50 200.0 nM
O=c1[nH]nc(SCc2noc3ccccc23)nc1O CHEMBL3785419 IC50 200.0 nM
O=c1[nH]c2nccc(Cl)c2[nH]c1=O CHEMBL3804851 IC50 210.0 nM
O=c1[nH]cc(SCc2ccccc2Cl)cc1O CHEMBL3906223 IC50 210.0 nM
O=c1[nH]c(=O)n(Cc2ccc3ccccc3c2)nc1O CHEMBL3613920 IC50 220.0 nM
CN(CC1CC1)c1cc(O)c(=O)[nH]n1 CHEMBL3891296 IC50 220.0 nM
Cc1cc(C(=O)O)cs1 CHEMBL4276865 IC50 220.0 nM
O=c1[nH]c2nccc(Br)c2[nH]c1=O CHEMBL3804953 IC50 230.0 nM
O=c1[nH]cc(SCc2cc(F)cc(Cl)c2)cc1O CHEMBL3912489 IC50 230.0 nM
O=c1[nH]c(=O)n(CCc2cccc(Oc3ccccc3)c2)nc1O CHEMBL3613944 IC50 240.0 nM
Cc1cccc(CSc2c[nH]c(=O)c(O)c2)c1 CHEMBL3933219 IC50 240.0 nM
O=c1[nH]cc(SCc2cccnc2)cc1O CHEMBL3968785 IC50 250.0 nM
N#Cc1[nH]c(=O)c(=O)[nH]c1CCc1ccc(C(F)(F)F)cc1 CHEMBL5176414 IC50 250.0 nM
O=c1[nH]cc(SCc2ccc(C(F)(F)F)nc2)[nH]c1=O CHEMBL5181983 IC50 250.0 nM
CC(C)CCn1nc(O)c(=O)[nH]c1=O CHEMBL3613914 IC50 260.0 nM
Cc1cccc(CCc2c[nH]c(=O)c(O)c2)c1 CHEMBL3907406 IC50 260.0 nM
O=C(O)c1cc2ccsc2[nH]1 CHEMBL496305 IC50 269.0 nM
COc1ccccc1CCn1nc(O)c(=O)[nH]c1=O CHEMBL3613938 IC50 270.0 nM
O=c1[nH]nc(C2CCCCC2)cc1O CHEMBL2338792 IC50 300.0 nM
O=c1cc(CSc2ccc(F)cc2)occ1O CHEMBL2158321 IC50 300.0 nM
CC(C)(C)c1ccc(CSc2n[nH]c(=O)c(O)n2)cc1 CHEMBL3787187 IC50 300.0 nM
O=c1[nH]cc(SCc2ccc(F)c(F)c2)[nH]c1=O CHEMBL5200372 IC50 300.0 nM
O=c1[nH]c(=O)n(CCn2ccc3cccnc32)nc1O CHEMBL3613926 IC50 310.0 nM
CN(C)S(=O)(=O)c1ccc(OCc2cn(C/C(F)=C/CN)nn2)cc1 CHEMBL4569453 pIC50 316.23 nM
CN(C)S(=O)(=O)c1ccc(OCc2cn(C/C(F)=C/CN)nn2)c(Cl)c1 CHEMBL4531065 pIC50 316.23 nM
O=c1[nH]cc(CCc2ccc(Cl)cc2)[nH]c1=O CHEMBL5202673 IC50 320.0 nM
COc1ccc(CCc2c[nH]c(=O)c(=O)[nH]2)cc1 CHEMBL5186984 IC50 320.0 nM
O=c1[nH]cc(CCc2ccc(-c3cc(O)n[nH]3)c(F)c2)[nH]c1=O CHEMBL5178020 IC50 320.0 nM
O=c1[nH]c(=O)n(CCn2cccn2)nc1O CHEMBL3613924 IC50 330.0 nM
Cc1c(F)cnc2[nH]c(=O)c(=O)[nH]c12 CHEMBL3805642 IC50 340.0 nM
O=c1[nH]cc(CCc2ccc(C(F)(F)F)cc2)[nH]c1=O CHEMBL5194769 IC50 340.0 nM
O=c1[nH]cc(CCc2ccccc2)[nH]c1=O CHEMBL5202169 IC50 340.0 nM
O=C(O)c1cc(Cl)c(Cl)o1 CHEMBL511101 IC50 343.0 nM
Cc1ccccc1CCc1c[nH]c(=O)c(O)c1 CHEMBL3931854 IC50 350.0 nM
O=c1[nH]cc(SCc2ccc(Cl)cn2)cc1O CHEMBL3944630 IC50 360.0 nM
Cc1cc(C(=O)O)sc1Cl CHEMBL4292441 IC50 360.0 nM
O=c1[nH]nc(CC2CC2)cc1O CHEMBL3952330 IC50 380.0 nM
Cc1ccccc1CSc1c[nH]c(=O)c(O)c1 CHEMBL3901512 IC50 390.0 nM
O=C(O)CNC(=O)c1cc(NC(=O)c2cc(Br)c(Br)[nH]2)c[nH]1 CHEMBL4226378 IC50 390.0 nM
O=c1[nH]c2ccc(F)cc2n1O CHEMBL2152740 IC50 400.0 nM
O=c1[nH]c(=O)n(CC(F)(F)c2ccccc2)nc1O CHEMBL3613948 IC50 400.0 nM
O=c1[nH]cc(C2COc3ccccc3S2)[nH]c1=O CHEMBL5178002 IC50 406.0 nM
Oc1noc2ccccc12 CHEMBL444173 IC50 418.0 nM
O=c1[nH]c(=O)n(CCn2cnc3ccccc32)nc1O CHEMBL3613925 IC50 440.0 nM
N#Cc1cccc(CSc2c[nH]c(=O)c(=O)[nH]2)c1 CHEMBL5205206 IC50 440.0 nM
O=c1[nH]cc(SCc2ccccn2)cc1O CHEMBL3953346 IC50 460.0 nM
O=c1[nH]c(=O)n(CC(O)c2ccccc2)nc1O CHEMBL3613950 IC50 470.0 nM
Cc1cc(C(=O)O)n[nH]1 CHEMBL391574 IC50 473.0 nM
Cc1ccc(CSc2c[nH]c(=O)c(O)c2)nc1 CHEMBL3930262 IC50 490.0 nM
O=c1[nH]cc(S(=O)(=O)Cc2ccccc2)cc1O CHEMBL3972972 IC50 490.0 nM
CN(CC(=O)O)C(=O)c1cc(NC(=O)c2cc(Br)c(Br)[nH]2)c[nH]1 CHEMBL4227763 IC50 490.0 nM
O=c1cc(CCc2ccccc2)occ1O CHEMBL2397822 IC50 500.0 nM
O=c1cc(COc2ccc(Cl)c(Cl)c2)occ1O CHEMBL2397742 IC50 500.0 nM
O=c1[nH]c(Cl)c(CCc2ccc(C(F)(F)F)cc2)[nH]c1=O CHEMBL5184409 EC50 500.0 nM
O=C(O)c1cc2scnc2[nH]1 CHEMBL496304 IC50 516.0 nM
O=c1[nH]cc(CCc2ccc3ncccc3c2)[nH]c1=O CHEMBL5179137 IC50 580.0 nM
O=c1[nH]c2ccccc2n1O CHEMBL2152720 IC50 600.0 nM
O=c1[nH]nc(SCC2CCCCC2)nc1O CHEMBL3787311 IC50 600.0 nM
Cc1n[nH]c2cc(CCc3c[nH]c(=O)c(=O)[nH]3)ccc12 CHEMBL5186364 IC50 640.0 nM
CC(C)(C)CCc1cc(O)c(=O)[nH]n1 CHEMBL2338793 IC50 670.0 nM
O=c1[nH]cc(CCc2ccc(OC(F)F)nc2)[nH]c1=O CHEMBL5203007 IC50 670.0 nM
O=c1cc(COc2ccc(Cl)cc2)occ1O CHEMBL2397741 IC50 700.0 nM
O=c1[nH]nc(SCc2cccc(-c3ccccc3)c2)nc1O CHEMBL3787629 IC50 700.0 nM
O=C(O)c1ccc(Cl)s1 CHEMBL4280438 IC50 720.0 nM
O=C(O)c1cc2ccccc2[nH]1 CHEMBL278390 IC50 745.0 nM
O=c1[nH]c(=O)n(CCc2ccccn2)nc1O CHEMBL3613923 IC50 760.0 nM
O=c1[nH]nc(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1O CHEMBL3986099 IC50 760.0 nM
NCC(=CF)COc1ccc(F)cc1 CHEMBL5198317 IC50 780.0 nM
O=c1[nH]c2cnccc2cc1O CHEMBL510126 IC50 784.0 nM
O=c1[nH]c2c3c(ccc2n1O)CCO3 CHEMBL2152732 IC50 800.0 nM
O=c1cc(COc2ccc3ccccc3c2)occ1O CHEMBL2397745 IC50 800.0 nM
O=c1cc(COc2ccc(F)cc2)occ1O CHEMBL2397740 IC50 800.0 nM
O=C(Cn1nc(O)c(=O)[nH]c1=O)c1ccccc1 CHEMBL3613949 IC50 850.0 nM
O=c1[nH]c2cc(F)ccc2n1O CHEMBL2152735 IC50 900.0 nM
O=c1cc(COc2cccc3ccccc23)occ1O CHEMBL2397744 IC50 900.0 nM
O=c1cc(COc2ccccc2)occ1O CHEMBL2397739 IC50 900.0 nM
O=c1[nH]c2ncccc2n1O CHEMBL2152718 IC50 1000.0 nM
O=c1[nH]cc(SCc2cnccn2)cc1O CHEMBL3890823 IC50 1000.0 nM