C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4448070 IC50 0.25 nM
COc1cc(-c2nc(SCc3ccc4ccccc4c3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5076401 IC50 2.25 nM
COc1cc(-c2nc(SCc3ccc(C)cc3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5075399 IC50 2.86 nM
CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCOc2ccccc21)C1CCCC1 CHEMBL4128590 Kd 4.1 nM
COC(=O)c1ccc(CSc2nc(Sc3nccs3)c(C#N)c(-c3cc(OC)c(OC)c(OC)c3)n2)cc1 CHEMBL5070367 IC50 5.36 nM
COc1cc(-c2nc(SCc3cccc(C)c3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5091659 IC50 5.48 nM
CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN(C)C)C(=O)N[C@@H]1CCOc2ccccc21)C1CCCC1 CHEMBL4129669 Kd 5.7 nM
COc1cc(-c2nc(SCc3ccc4ccccc4c3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5092564 IC50 6.15 nM
CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCOc2ccccc21)C1CCOCC1 CHEMBL4127438 Kd 6.7 nM
CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL4129556 Kd 8.1 nM
COc1cc(-c2nc(SCc3ccc(Cl)cc3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5085822 Ki 8.26 nM
CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCCc2ccccc21)C1CCCC1 CHEMBL4128753 Kd 8.3 nM
COc1cc(-c2nc(SCc3ccc(C)cc3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5086499 IC50 9.37 nM
COc1cc(-c2nc(SCc3cccc(C)c3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5082310 IC50 11.07 nM
COc1cc(-c2nc(SCc3ccc(C(C)(C)C)cc3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5078162 IC50 11.48 nM
CCC(=O)N[C@@H](Cc1nc2ccc(C(C)C)cc2s1)C(=O)N[C@H](CNC(=O)CCN1CCOCC1)C1CCCCC1 CHEMBL4517307 Ki 12.0 nM
COc1cc(-c2nc(SCc3cccc(C(F)(F)F)c3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5089618 IC50 12.16 nM
COc1cc(-c2nc(SCc3cccc(C)c3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5091608 IC50 12.4 nM
COc1ccc(CSc2nc(Sc3nnnn3CCN(C)C)c(C#N)c(-c3cc(OC)c(OC)c(OC)c3)n2)cc1 CHEMBL5085047 IC50 13.41 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2ccc(C)cc2)n1 CHEMBL4592844 Ki 13.66 nM
COc1ccc(-c2nc(SCc3ccc(C)cc3)nc(Sc3nccs3)c2C#N)cc1OC CHEMBL5074683 IC50 17.14 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc3ccccc3c2)CC1 CHEMBL4067795 IC50 18.0 nM
CCC(=O)N[C@@H](Cc1nc2ccc(C(C)C)cc2s1)C(=O)N[C@@H](CNC(=O)CCN1CCOCC1)C1CCCCC1 CHEMBL4851208 IC50 20.82 nM
Cc1ccc(CSc2nc(Sc3nccs3)c(C#N)c(-c3ccc(C)cc3)n2)cc1 CHEMBL5089944 IC50 20.88 nM
COc1ccc(-c2nc(SCc3ccc(C)cc3)nc(Sc3nccs3)c2C#N)cc1 CHEMBL5089246 IC50 21.17 nM
c1ccc(-c2ccccc2-c2nnc(SSc3nnc(-c4ccccc4-c4ccccc4)[nH]3)[nH]2)cc1 CHEMBL4865016 Ki 22.92 nM
COc1cc(-c2nc(SCc3ccc(Cl)cc3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5080691 IC50 24.74 nM
COc1cc(-c2nc(SCc3ccc(Cl)cc3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5089086 IC50 25.31 nM
COc1cc(-c2nc(SCc3cccc(C(F)(F)F)c3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5087586 IC50 25.77 nM
Cc1ccc(CSc2nc(Sc3nccs3)c(C#N)c(-c3ccc(Br)cc3)n2)cc1 CHEMBL5093455 IC50 27.9 nM
COc1cc(-c2nc(SCc3ccccc3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5089436 IC50 28.11 nM
COc1cc(-c2nc(SCc3ccccc3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5080436 IC50 28.21 nM
COc1cc(-c2nc(SCc3ccc(C(F)(F)F)cc3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5085671 IC50 29.07 nM
COc1cc(-c2nc(SCc3cccc(C(F)(F)F)c3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5092062 IC50 29.29 nM
COc1ccc(CSc2nc(Sc3nnnn3C)c(C#N)c(-c3cc(OC)c(OC)c(OC)c3)n2)cc1 CHEMBL5076837 IC50 31.23 nM
CCC(=O)N[C@@H](Cc1nc2ccccc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL4128744 Kd 31.8 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL4125758 Ki 36.3 nM
COc1cc(-c2nc(SCc3ccccc3)nc(Sc3nnnn3C)c2C#N)cc(OC)c1OC CHEMBL5084048 IC50 36.35 nM
COc1cc(-c2nc(SCc3ccc4ccccc4c3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5091159 IC50 36.35 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2ccc(Cl)cc2)n1 CHEMBL4470342 IC50 36.59 nM
C=CCSc1nc(Sc2nccs2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL5084356 IC50 36.86 nM
CCC(=O)N[C@@H](Cc1nc2ccc(F)cc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL4128331 Kd 37.0 nM
COc1cc(-c2nc(SCc3ccccc3)nc(Sc3nc(C)cs3)c2C#N)cc(OC)c1OC CHEMBL5078620 IC50 41.09 nM
COc1cc(-c2nc(SCc3ccc(C)cc3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5080829 IC50 42.23 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL4129566 Ki 42.9 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL4129300 Ki 44.3 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(Cl)c(Cl)c2)CC1 CHEMBL4074213 IC50 45.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4099097 IC50 50.0 nM
c1ccc(-c2nnc(SSc3nnc(-c4ccccc4)[nH]3)[nH]2)cc1 CHEMBL4878599 IC50 50.58 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(I)cc2)CC1 CHEMBL4077431 IC50 54.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cc(F)cc(C(F)(F)F)c2)CC1 CHEMBL4077759 IC50 58.0 nM
C=CC(=O)Nc1ccccc1CN(C(=O)Nc1cccc(C(F)(F)F)c1)C1CCN(C(C)CCC)CC1 CHEMBL4440896 IC50 58.21 nM
COc1cc(-c2nc(SCc3ccc(C(F)(F)F)cc3)nc(Sc3nnnn3CCN(C)C)c2C#N)cc(OC)c1OC CHEMBL5077779 IC50 60.54 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL4534046 IC50 62.99 nM
C#CCSc1nc(Sc2nnnn2CCN(C)C)c(C#N)c(-c2ccc(Cl)cc2)n1 CHEMBL4442915 IC50 63.51 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2ccc(C)cc2)n1 CHEMBL4570218 IC50 64.75 nM
Cc1ccc(CSc2nc(Sc3nccs3)c(C#N)c(-c3ccc(Cl)cc3)n2)cc1 CHEMBL5086488 IC50 65.87 nM
C#CCSc1nc(Sc2ccc(N)s2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4585567 IC50 65.98 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(Br)cc2)CC1 CHEMBL4094517 IC50 68.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc3c(c2)CCC3)CC1 CHEMBL4078685 IC50 77.0 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4530739 IC50 77.04 nM
COc1ccccc1-c1nnc(SSc2nnc(-c3ccccc3OC)[nH]2)[nH]1 CHEMBL4869654 IC50 77.55 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2ccc(Cl)cc2)n1 CHEMBL4464015 IC50 78.49 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)CC1 CHEMBL4103209 IC50 82.0 nM
Cc1ccccc1-c1nnc(SSc2nnc(-c3ccccc3C)[nH]2)[nH]1 CHEMBL4847848 IC50 83.91 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCCc2ccccc21)[C@@H](C)CC CHEMBL4128493 Ki 84.0 nM
c1cc2c(cc1-c1nnc(SSc3nnc(-c4ccc5c(c4)OCO5)[nH]3)[nH]1)OCO2 CHEMBL4847553 IC50 85.81 nM
Sc1n[nH]c(-c2cccc(Br)c2)n1 CHEMBL1334768 IC50 86.05 nM
CCC(=O)N[C@@H](Cc1nc2cc(Cl)ccc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL4128177 Ki 88.6 nM
Brc1cccc(-c2nnc(SSc3nnc(-c4cccc(Br)c4)[nH]3)[nH]2)c1 CHEMBL4860176 IC50 92.34 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)[C@@H](C)CC CHEMBL4127729 Ki 97.0 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCCC1 CHEMBL4125864 Ki 97.3 nM
COc1cc(-c2nc(SCc3ccc(C(F)(F)F)cc3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5075282 IC50 100.14 nM
C#CCSc1nc(Sc2nnnn2CCN(C)C)c(C#N)c(-c2cccc(Cl)c2)n1 CHEMBL4458672 IC50 106.21 nM
C#CCSc1nc(Sc2nnc(N)s2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4576317 IC50 106.73 nM
Oc1ccccc1-c1nnc(SSc2nnc(-c3ccccc3O)[nH]2)[nH]1 CHEMBL4874768 IC50 107.56 nM
C#CCSc1nc(Sc2nnnn2CCN(C)C)c(C#N)c(-c2ccc(C)cc2)n1 CHEMBL4476338 IC50 109.04 nM
CCCCN1CCC(N(Cc2ccc3c(c2)OCO3)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4072130 EC50 110.0 nM
CCN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(CN)nn(-c3ccccc3)c21 CHEMBL4876194 IC50 110.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(Cl)cc2)CC1 CHEMBL4086099 IC50 112.0 nM
O=S(=O)(c1cccc(-c2nnc(SSc3nnc(-c4cccc(S(=O)(=O)N5CCOCC5)c4)[nH]3)[nH]2)c1)N1CCOCC1 CHEMBL4854235 IC50 115.0 nM
Clc1ccccc1-c1nnc(SSc2nnc(-c3ccccc3Cl)[nH]2)[nH]1 CHEMBL4851610 IC50 121.21 nM
C#CCSc1nc(Sc2nnc(C)s2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4450113 IC50 133.6 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CCCc2ccccc21)[C@@H](C)CC CHEMBL4129541 Ki 140.0 nM
CCCCS(=O)(=O)N1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4226555 IC50 140.0 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4102019 EC50 140.0 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2cccc(Cl)c2)n1 CHEMBL4445001 IC50 140.38 nM
C#CCSc1nc(Sc2nncs2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4476364 IC50 141.22 nM
Fc1ccccc1-c1nnc(SSc2nnc(-c3ccccc3F)[nH]2)[nH]1 CHEMBL4868697 IC50 144.74 nM
Cc1ccc(-c2nnc(SSc3nnc(-c4ccc(C)cc4)[nH]3)[nH]2)cc1 CHEMBL4871768 IC50 145.99 nM
Brc1ccccc1-c1nnc(SSc2nnc(-c3ccccc3Br)[nH]2)[nH]1 CHEMBL4846458 IC50 155.8 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1CCc2ccccc21)[C@@H](C)CC CHEMBL4127532 Ki 160.0 nM
CC(C)(C)CCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4225246 IC50 170.0 nM
C#CCSc1nc(Sc2nnnn2CCN(C)C)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL4444162 IC50 172.29 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1cccs1)C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL4128328 Ki 174.0 nM
CCCN1CCC(N(Cc2cc(F)cc(C(F)(F)F)c2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4063514 EC50 180.0 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2ccc(Br)cc2)n1 CHEMBL4454488 IC50 189.41 nM
C#CCSc1nc(Sc2nnnn2CCN(C)C)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL4539394 IC50 199.07 nM
C#CCSc1nc(Sc2nccs2)c(C#N)c(-c2ccc3oc(=O)ccc3c2)n1 CHEMBL4451681 IC50 202.05 nM
O=C(Nc1cccc(C(F)(F)F)c1)N(Cc1ccccc1)C1CCN(CC2CC2)CC1 CHEMBL4077751 IC50 210.0 nM
CCC(=O)N[C@@H](Cc1nc2cc(F)ccc2s1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1)C1CCCC1 CHEMBL4129396 Ki 224.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(C)c(F)c2)CC1 CHEMBL4065355 IC50 241.0 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cc(F)cc(C(F)(F)F)c2)CC1 CHEMBL4079749 IC50 256.0 nM
CCCSc1nc(Sc2nccs2)c(C#N)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL5089594 IC50 258.34 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CC1 CHEMBL4105639 IC50 260.0 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2ccc(Br)cc2)n1 CHEMBL4444958 IC50 281.65 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(F)c(C(F)(F)F)c2)CC1 CHEMBL4087755 IC50 290.0 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2cccc(Cl)c2)n1 CHEMBL4530095 IC50 290.65 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(Cl)c2)CC1 CHEMBL4077301 IC50 304.0 nM
CC(C)(C)N1CCC(N(Cc2ccc3c(c2)OCO3)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4103922 IC50 310.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(C(F)(F)F)cc2)CC1 CHEMBL4064579 IC50 314.0 nM
Clc1ccc(-c2nnc(SSc3nnc(-c4ccc(Cl)cc4)[nH]3)[nH]2)cc1 CHEMBL4866253 IC50 319.92 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(C)c(Cl)c2)CC1 CHEMBL4103413 IC50 325.0 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL4475475 IC50 338.83 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(C)C)c2)CC1 CHEMBL4093853 IC50 353.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(C)cc2)CC1 CHEMBL4102261 IC50 356.0 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(Cl)c2)CC1 CHEMBL4093655 IC50 358.0 nM
O=C(Nc1cccc(C(F)(F)F)c1)N(Cc1ccccc1)C1CCN(Cc2ccc3c(c2)OCCO3)CC1 CHEMBL4226839 IC50 360.0 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2ccc(C(C)C)cc2)n1 CHEMBL4446445 IC50 368.76 nM
O=C(Nc1cccc(C(F)(F)F)c1)N(Cc1ccccc1)C1CCN(CC2CCCC2)CC1 CHEMBL4228742 IC50 370.0 nM
Sc1nnc(-c2ccccc2-c2ccccc2)[nH]1 CHEMBL4860279 IC50 377.57 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CCc2ccccc21)[C@@H](C)CC CHEMBL4128931 Ki 380.0 nM
CCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4078680 EC50 400.0 nM
COc1cc(-c2nc(SCc3c(C)noc3C)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5088227 IC50 412.24 nM
COc1cc(-c2nc(SCc3ccoc3C(F)(F)F)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5094811 IC50 450.12 nM
Cc1ccc(CSc2nc(Sc3nccs3)c(C#N)c(-c3ccccc3C)n2)cc1 CHEMBL5084700 IC50 462.58 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cc(F)cc(Cl)c2)CC1 CHEMBL4102027 IC50 481.0 nM
CCCN1CCC(N(Cc2ccc3c(c2)OCO3)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4104419 EC50 490.0 nM
Sc1n[nH]c(-c2ccccc2)n1 CHEMBL85091 IC50 500.0 nM
Sc1n[nH]c(-c2ccccc2Cl)n1 CHEMBL1448063 IC50 500.0 nM
Sc1n[nH]c(-c2ccccc2Br)n1 CHEMBL1447470 IC50 500.0 nM
Nc1ccccc1-c1nnc(S)[nH]1 CHEMBL4849618 IC50 500.0 nM
Sc1nnc(-c2ccc3c(c2)OCO3)[nH]1 CHEMBL4856019 IC50 500.0 nM
CCCN1CCC(N(Cc2ccco2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4096696 EC50 570.0 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2F)CC1 CHEMBL4065590 IC50 583.0 nM
COc1cccc(-c2nnc(SSc3nnc(-c4cccc(OC)c4)[nH]3)[nH]2)c1 CHEMBL4866516 IC50 584.95 nM
COc1cc(-c2nc(SCC3CCCCC3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5086779 IC50 611.2 nM
CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(F)c(C(F)(F)F)c2)CC1 CHEMBL4085483 IC50 612.0 nM
O=C(Nc1cccc(C(F)(F)F)c1)N(Cc1ccccc1)C1CCN(CC2CCCCC2)CC1 CHEMBL4224981 IC50 620.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc3ncsc3c2)CC1 CHEMBL4096706 IC50 626.0 nM
COc1cc(-c2nc(SCc3ccncc3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5089354 IC50 653.4 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(C(C)C)cc2)CC1 CHEMBL4084296 IC50 654.0 nM
CCCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4225926 IC50 660.0 nM
C#CCSc1nc(Sc2nnnn2CCN(C)C)c(C#N)c(-c2ccc3oc(=O)ccc3c2)n1 CHEMBL4465987 IC50 665.64 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC(F)(F)F)C(=O)N[C@@H](CCCCN)C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL4129711 Ki 672.0 nM
O=S(=O)(c1cccc(-c2nnc(S)[nH]2)c1)N1CCOCC1 CHEMBL4869738 IC50 706.88 nM
Fc1ccccc1-c1nnc(S)[nH]1 CHEMBL4875837 IC50 710.78 nM
CCCS(=O)(=O)N1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4225712 IC50 740.0 nM
CC(C)CCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4229003 IC50 790.0 nM
CCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCc1ccccc1)[C@@H](C)CC CHEMBL4126189 Ki 810.0 nM
COc1cc(-c2nc(SCc3nc4ccccc4[nH]3)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5077947 IC50 814.12 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(F)c(F)c2)CC1 CHEMBL4086785 IC50 817.0 nM
C#CCSc1nc(Sc2nnnn2C)c(C#N)c(-c2ccc3oc(=O)ccc3c2)n1 CHEMBL4440732 IC50 820.0 nM
COc1cc(-c2nc(SCc3ccccc3C)nc(Sc3nccs3)c2C#N)cc(OC)c1OC CHEMBL5094775 IC50 890.09 nM
CC(C)(C)CN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2)CC1 CHEMBL4225510 IC50 960.0 nM
CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc3c(c2)OCO3)CC1 CHEMBL4089008 IC50 990.0 nM