Cc1ncccc1-c1c(Cl)sc2ccc(NC(=O)NCC(=O)NCCCN(C)[C@@H]3CCCN(c4ncnc5[nH]ccc45)C3)cc12 CHEMBL4099771 Ki 0.002 nM
CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL3414626 Ki 0.012 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL3087498 Kd 0.06 nM
CNc1ccnc(Nc2ccc3cc(C)n(-c4ccccc4Oc4cnc5c(c4)ncn5C)c3c2)n1 CHEMBL4590355 Ki 0.08 nM
COc1nc(Nc2cc(S(C)(=O)=O)ccc2N[C@@H](c2cccc3c2OC(F)(F)O3)c2ncccc2Cl)nc(N2CCNCC2)n1 CHEMBL4446126 IC50 0.11 nM
CN(CCCNC(=O)CNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1)[C@@H]1CCCN(c2ncnc3[nH]ccc23)C1 CHEMBL4081752 IC50 0.15 nM
COc1nc(N)nc(Nc2cc(S(N)(=O)=O)ccc2N[C@@H](c2cccc3c2OC(F)(F)O3)c2ncccc2Cl)n1 CHEMBL4435508 IC50 0.17 nM
COc1nc(Nc2cc(S(C)(=O)=O)ccc2N[C@@H](c2cccc3c2OC(F)(F)O3)c2ncccc2Cl)nc(OC)n1 CHEMBL4567485 IC50 0.19 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL2169919 Kd 0.25 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@@H]1O[C@H](n2cc(Br)c3c(N)ncnc32)[C@@H](O)[C@H]1O CHEMBL5188291 IC50 0.3 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@@H]1O[C@H](n2ccc3c(N)ncnc32)[C@@H](O)[C@H]1O CHEMBL5176983 IC50 0.3 nM
CNc1ccnc(Nc2ccc3sc(Cl)c(-c4cc(-c5c(C)ncn(C)c5=O)cnc4Cl)c3c2)n1 CHEMBL4534250 Ki 0.36 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL2171169 Ki 0.46 nM
CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(Cl)c(C(F)(F)F)cc3[nH]2)C1 CHEMBL4112081 IC50 0.59 nM
CC(C)N(C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL4106621 IC50 0.59 nM
COc1nc(Nc2cc(S(C)(=O)=O)ccc2N[C@@H](c2cccc(Cl)c2F)c2ncccc2F)nc(OC)n1 CHEMBL4557484 IC50 0.59 nM
CN(C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL4114909 IC50 0.62 nM
CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL4079133 IC50 0.73 nM
CNc1ncnc2c1ncn2[C@@H]1O[C@H](CN(CCCNC(=O)Nc2ccc(C(C)(C)C)cc2)C(C)C)[C@@H](O)[C@H]1O CHEMBL2171170 Ki 0.76 nM
CC(C)N(C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(OC(F)(F)F)ccc3[nH]2)C1 CHEMBL4107547 IC50 0.8 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL3087503 Ki 1.1 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)CC1=C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL3087502 Ki 1.3 nM
CS(=O)(=O)c1ccc(N[C@H](c2ccccn2)c2cccc(Cl)c2F)c(Nc2nccc(C(N)=O)n2)c1 CHEMBL4448208 IC50 2.1 nM
CC(C)N(C[C@H]1C[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL5196874 IC50 2.1 nM
CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(OC(F)(F)F)ccc3[nH]2)C1 CHEMBL4108783 IC50 2.18 nM
CN(C[C@H]1C[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL4115320 IC50 2.51 nM
CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(OC(F)(F)F)ccc3[nH]2)C1 CHEMBL4107217 IC50 2.92 nM
O=C(CNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1)NCCCN[C@@H]1CCCN(c2ncnc3[nH]ccc23)C1 CHEMBL4066397 pIC50 3.981 nM
O=C(CNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1)NCCCCN[C@@H]1CCCN(c2ncnc3[nH]ccc23)C1 CHEMBL4087730 pIC50 3.981 nM
CN(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)CC1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL3643719 IC50 6.0 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)[C@@H](C)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL4075482 IC50 6.34 nM
CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)C1CC(CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL3087499 EC50 9.0 nM
CNc1ccnc(Nc2ccc3cc(C)n(-c4cc(-c5c(C)ccn(C)c5=O)cnc4Cl)c3c2)n1 CHEMBL4549878 IC50 10.0 nM
C=CCNc1ncnc2c1ncn2[C@@H]1O[C@H](CN(CCCNC(=O)Nc2ccc(C(C)(C)C)cc2)C(C)C)[C@@H](O)[C@H]1O CHEMBL2171171 Ki 12.0 nM
CN(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL3087500 Ki 13.0 nM
N#Cc1cn([C@@H]2O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL4588797 IC50 13.0 nM
N#Cc1cn([C@H]2O[C@@H](CSCC[C@H](N)C(=O)O)[C@H](O)[C@@H]2O)c2ncnc(N)c12 CHEMBL5174254 IC50 13.0 nM
CC(C)N(C[C@H]1C[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL5174048 IC50 13.8 nM
Nc1ncnc2ccc(N(CC#CC(O)c3nccn3CCO)c3c(Cl)cccc3Cl)cc12 CHEMBL4452414 IC50 14.0 nM
CS(=O)(=O)c1ccc(N[C@@H](c2cccc(Cl)c2F)c2ncccc2F)c(Nc2ncccn2)c1 CHEMBL4589340 IC50 16.0 nM
CN(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1C[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O CHEMBL5191411 IC50 19.0 nM
O=C(Cn1nnnc1-c1ccccc1Cl)NNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1 CHEMBL4586619 IC50 20.0 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL2171172 Ki 22.0 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cc(Cl)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL4559614 IC50 28.2 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL2349526 Ki 38.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CN(CCI)CCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL3087638 IC50 38.0 nM
Nc1ncnc2c1ncn2[C@H]1O[C@@H](CN(CCI)CCC[C@H](N)C(=O)O)[C@H](O)[C@@H]1O CHEMBL5197586 IC50 38.0 nM
Cc1ccc(C#CCN(c2ccc3ncnc(N)c3c2)c2c(Cl)cccc2Cl)nc1 CHEMBL4436922 IC50 47.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(C(F)(F)F)cc2)[C@@H](O)[C@H]1O CHEMBL2170997 Ki 58.0 nM
CNc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(C(C)(C)C)cc2)[C@@H](O)[C@H]1O CHEMBL2170993 Ki 70.0 nM
CC(C)(C)c1ccc(NC(=O)NCCCSC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1 CHEMBL3087504 Ki 70.0 nM
Nc1ncnc2c1c(Br)cn2[C@H]1O[C@@H](CSCC[C@H](N)C(=O)O)[C@H](O)[C@@H]1O CHEMBL5205286 IC50 77.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H](O)[C@H]1O CHEMBL2171002 Ki 80.0 nM
CC(C)N(C[C@@H]1C[C@H](c2ccc3c(N)ncnn23)[C@@H](O)[C@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 CHEMBL5197744 IC50 80.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(Cl)cc2)[C@@H](O)[C@H]1O CHEMBL2170994 Ki 82.0 nM
Cc1ncc(C#CCN(c2ccc3ncn(C)c(=O)c3c2)c2c(Cl)cccc2Cl)cn1 CHEMBL4548823 IC50 89.0 nM
CS(=O)(=O)c1ccc(N[C@H](c2ccccn2)c2cccc(Cl)c2F)c(Nc2ncccn2)c1 CHEMBL4587469 IC50 97.0 nM
N[C@@H](CCCN(CCI)C[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O)C(=O)O CHEMBL2169918 IC50 110.0 nM
CNc1ncnc2c1ncn2[C@@H]1O[C@H](CN(CCI)CCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL2172427 IC50 120.0 nM
CNc1ncnc2c1ncn2[C@H]1O[C@@H](CN(CCI)CCC[C@H](N)C(=O)O)[C@H](O)[C@@H]1O CHEMBL5201124 IC50 120.0 nM
CCc1cccc(NC(=O)NCCCSC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)c1 CHEMBL2171000 Ki 130.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(OC(F)(F)F)cc2)[C@@H](O)[C@H]1O CHEMBL2170998 Ki 140.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL418052 IC50 140.0 nM
CNc1ccnc(Nc2ccc3cc(C)n(-c4ccccc4Oc4ccccc4)c3c2)n1 CHEMBL4577516 IC50 150.0 nM
Nc1ncnc2c1ncn2[C@H]1O[C@@H](CSCC[C@H](N)C(=O)O)[C@H](O)[C@@H]1O CHEMBL5172325 Ki 160.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCC(N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL45041 IC50 170.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(Br)cc2)[C@@H](O)[C@H]1O CHEMBL2170995 Ki 190.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(I)cc2)[C@@H](O)[C@H]1O CHEMBL2170996 Ki 270.0 nM
CS(=O)(=O)c1ccc(N[C@@H](c2cccc(Cl)c2)c2ccccn2)c(Nc2ncccn2)c1 CHEMBL4531049 IC50 270.0 nM
CNc1ccnc(Nc2ccc3cc(C)n(-c4cccnc4Cl)c3c2)n1 CHEMBL4573709 IC50 280.0 nM
CNc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL2171174 Ki 290.0 nM
CNc1ncnc2c1ncn2[C@H]1O[C@@H](CSCC[C@H](N)C(=O)O)[C@H](O)[C@@H]1O CHEMBL5194696 Ki 290.0 nM
CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1C[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O CHEMBL5170014 IC50 292.0 nM
CC(C)c1ccc(NC(=O)NCCCSC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1 CHEMBL2170992 Ki 350.0 nM
CN(CCCNC(=O)Nc1ccccc1)C[C@H]1C[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O CHEMBL5208714 IC50 369.0 nM
COc1cc([C@H]2Oc3c(O)cc(CCCO)cc3[C@@H]2CO)ccc1O[C@@H]1O[C@@H](C)[C@@H](O)[C@@H](O)[C@H]1O CHEMBL5182206 IC50 399.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccccc2)[C@@H](O)[C@H]1O CHEMBL2170989 Ki 550.0 nM
CCc1ccccc1NC(=O)NCCCSC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL2170999 Ki 690.0 nM
C[C@H](NC1CC(CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL4095543 IC50 690.0 nM
Cn1cnc2ccc(N(CC#Cc3cccnc3)c3c(Cl)cccc3Cl)cc2c1=O CHEMBL4446348 IC50 840.0 nM
C#CCN(c1ccc2ncnc(N)c2c1)c1c(Cl)cccc1Cl CHEMBL4475242 IC50 920.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCNC(=O)Nc2ccc(F)cc2F)[C@@H](O)[C@H]1O CHEMBL2171001 Ki 1000.0 nM
CC(C)(C)c1ccc(NC(=O)c2ncn(CC(=O)NCCn3ccc4c(N)ncnc43)n2)cc1 CHEMBL4765125 IC50 1000.0 nM
CC(C)(C)c1ccc(CC(=O)c2ncn(CC(=O)NCCn3ccc4c(N)ncnc43)n2)cc1 CHEMBL5194873 IC50 1000.0 nM