Cc1cccc(CNCC(=O)c2cn3c(-c4ccc(Cl)cc4Cl)c(CN)c(C)nc3n2)n1 CHEMBL1215374 Ki 0.086 nM
Cc1nc2nc(C(=O)NCCc3ccccn3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215376 Ki 0.27 nM
Cc1nc2nc(C(=O)N(C)Cc3cccnc3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215167 Ki 0.4 nM
Cc1nc2nc(C(=O)N3CCN(S(C)(=O)=O)CC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215087 Ki 0.42 nM
Cc1nc2nc(C(=O)NCCc3ccncc3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215448 Ki 0.58 nM
Cc1nc2nc(C(=O)NCCc3cccnc3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215375 Ki 0.6 nM
Cc1nc2nc(C(=O)Nc3nc(-c4cccnc4)cs3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215302 Ki 0.65 nM
Cc1cc(NC(=O)c2cn3c(-c4ccc(Cl)cc4Cl)c(CN)c(C)nc3n2)n(C)n1 CHEMBL1215089 Ki 0.7 nM
CCN(CC)C(=O)CN1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441846 Ki 0.8 nM
Cc1nc2nc(C(=O)N(C)CCc3ccccn3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215236 Ki 0.95 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(=O)N1CCCCC1)C2 CHEMBL2441955 Ki 1.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(=O)O)C2 CHEMBL2441844 Ki 1.0 nM
Cc1nc2nc(C(=O)N3COCC3(C)C)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215164 Ki 1.1 nM
Cc1nc2nc(C(=O)N(C)Cc3ccncc3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215299 Ki 1.1 nM
Cc1nc2nc(C(=O)N(C)Cc3ccco3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215301 Ki 1.2 nM
N=C(N)NCCC[C@H](N)C(=O)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063040 IC50 1.2 nM
COC[C@H]1CCCN1C(=O)c1cn2c(-c3ccc(Cl)cc3Cl)c(CN)c(C)nc2n1 CHEMBL1215017 Ki 1.3 nM
CCn1nccc1NC(=O)c1cn2c(-c3ccc(Cl)cc3Cl)c(CN)c(C)nc2n1 CHEMBL1215233 Ki 1.3 nM
Cc1nc2nc(C(=O)NCc3ccco3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215300 Ki 1.4 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(=O)N1CCCC1)C2 CHEMBL2441954 Ki 1.4 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(C[C@@H]1CCCO1)C2 CHEMBL2441839 Ki 1.4 nM
CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O CHEMBL67279 Ki 1.5 nM
CCN(CC)C(=O)c1cn2c(-c3ccc(Cl)cc3Cl)c(CN)c(C)nc2n1 CHEMBL1214877 Ki 1.7 nM
Cc1nc2nc(C(=O)Nc3ccon3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215166 Ki 1.7 nM
COC[C@H](C)N1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441837 Ki 1.7 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CCC(=O)O)C2 CHEMBL2441845 Ki 1.8 nM
N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2 CHEMBL142703 IC50 1.85 nM
CCOC(=O)c1cn2c(-c3ccc(Cl)cc3Cl)c(CN)c(C)nc2n1 CHEMBL1214876 Ki 1.9 nM
C[C@H](N)C(=O)N1CCC[C@H]1B(O)O CHEMBL63860 Ki 2.0 nM
Cc1nc2nc(C(=O)N3CC[C@H](NS(C)(=O)=O)C3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215018 Ki 2.0 nM
CCCN(C)C(=O)CN1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441953 Ki 2.0 nM
Cc1nc2nc(C(=O)N3CCCC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1214942 Ki 2.2 nM
Cc1nc2nc(C(=O)NC3CCOCC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1214944 Ki 2.2 nM
Cc1nc2nc(C(=O)N(C)CCS(C)(=O)=O)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215088 Ki 2.2 nM
Cc1nc2nc(C(=O)NCCc3c[nH]cn3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215373 Ki 2.2 nM
Cc1csc(NC(=O)c2cn3c(-c4ccc(Cl)cc4Cl)c(CN)c(C)nc3n2)n1 CHEMBL1215090 Ki 2.3 nM
Cc1nc2nc(C(=O)N3CCOCC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1214943 Ki 2.4 nM
Cc1nc2nc(C(=O)NCc3cccs3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215235 Ki 2.5 nM
Cc1nc2nc(C(=O)N3CCNC(=O)C3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215016 Ki 2.8 nM
COc1ccc(N2Cc3nc(C)c(CN)c(-c4ccc(Cl)cc4Cl)c3C2=O)cc1 CHEMBL2441829 Ki 2.8 nM
Cc1nc2nc(C(=O)NCc3ncco3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215163 Ki 2.9 nM
NCC(=O)N1CCC[C@H]1B(O)O CHEMBL67089 Ki 3.1 nM
CCN(CC)C(=O)[C@@H](C)N1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441848 Ki 3.8 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(C[C@@H]1CCCN1S(=O)(=O)C1CC1)C2 CHEMBL2441841 Ki 3.8 nM
COc1ccccc1N1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441830 Ki 3.8 nM
CCN(CC)C(=O)CCN1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441847 Ki 3.9 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(C[C@H]1CCCO1)C2 CHEMBL2441838 Ki 3.9 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)C1CCCC1 CHEMBL94278 Ki 4.0 nM
Cc1nc2nc(C(=O)Nc3ccn(C)n3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215165 Ki 4.1 nM
CNC(=O)CN1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441951 Ki 4.3 nM
Cc1nc2nc(C(=O)Nc3ccnn3C)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215234 Ki 4.5 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(=O)N(C)C)C2 CHEMBL2441952 Ki 4.9 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(Cc1ccn(C)n1)C2 CHEMBL2441833 Ki 5.2 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(c1ccccc1)C2 CHEMBL2441828 Ki 5.2 nM
COCCN1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O CHEMBL2441836 Ki 5.4 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(c1ccn(C)n1)C2 CHEMBL2441831 Ki 5.5 nM
O=C([C@@H]1CCCN1)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063033 IC50 5.9 nM
Cc1cc(CN2Cc3nc(C)c(CN)c(-c4ccc(Cl)cc4Cl)c3C2=O)no1 CHEMBL2441835 Ki 6.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(Cc1ccccc1)C2 CHEMBL2441832 Ki 6.4 nM
N[C@@H](CC(=O)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814741 Ki 6.5 nM
N[C@@H](CC(=O)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1)C(=O)N1Cc2ccc(F)cc2C1 CHEMBL1814740 IC50 8.8 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(Cc1ncco1)C2 CHEMBL2441834 Ki 8.9 nM
C[C@H](N)C(=O)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063024 IC50 9.2 nM
N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2ccc(F)cc2C1 CHEMBL1814739 IC50 9.4 nM
N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1B(O)O CHEMBL494497 Ki 11.0 nM
CC[C@@H](C)[C@H](N)C(=O)N1C[C@@H](N=[N+]=[N-])C[C@H]1C#N CHEMBL471547 IC50 11.0 nM
N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814633 IC50 12.0 nM
Cc1nc2cc(-c3ccccc3)nn2c(C)c1C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N CHEMBL1929394 IC50 12.0 nM
O=C([C@@H]1C[C@H](N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)CN1)N1CCSC1 CHEMBL391466 IC50 12.0 nM
Cc1nc2nc(C(=O)NCCN3CCCCC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN CHEMBL1215015 Ki 13.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(N)=O)C2 CHEMBL2441950 Ki 13.0 nM
N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)[C@@H](N)CCCCNc1ccc2ccccc2c1 CHEMBL472128 IC50 13.8 nM
NC(CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL367368 IC50 14.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL362018 IC50 14.0 nM
CC(C)[C@H](N)C(=O)N1CCC[C@@H]1B(O)O CHEMBL195189 IC50 15.0 nM
CC(C)(C)[C@H](N)C(=O)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063031 IC50 17.0 nM
C[C@H]1C[C@@H](C#N)N(C(=O)[C@@H](N)CC(=O)N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)C1 CHEMBL3798441 IC50 17.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CC(=O)N1CCc2ccccc2C1 CHEMBL179289 IC50 19.0 nM
COc1cc2c(cc1OC)CN(C(=O)C[C@H](N)C(=O)N1CCC[C@H]1C#N)CC2 CHEMBL369883 IC50 19.0 nM
O=C([C@@H]1C[C@H](O)CN1)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063037 IC50 19.0 nM
N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)[C@@H](N)CCCCNC(=O)OCc1ccccc1 CHEMBL471747 IC50 21.0 nM
CO[C@H]1C[C@H]2C[C@H](NCC(=O)N3CCC[C@H]3C#N)C[C@H]2C1 CHEMBL1082348 IC50 23.0 nM
C[C@H](N)C(=O)N1C[C@H](F)C[C@H]1B(O)O CHEMBL2063026 IC50 23.0 nM
N[C@H](C(=O)N1Cc2ccccc2C1)C1CCCCC1 CHEMBL440021 IC50 24.0 nM
N[C@H](C(=O)N1Cc2ccccc2C1)C1CCC(O)CC1 CHEMBL5425473 IC50 24.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)C1CCCCC1 CHEMBL307636 IC50 27.0 nM
O=C([C@@H]1C[C@@H](O)CN1)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063035 IC50 27.0 nM
N#Cc1ccc[n+](N2CCN(C(=O)C[C@H](N)C(=O)N3CCC[C@H]3C#N)CC2)c1 CHEMBL364922 IC50 28.0 nM
N[C@@H](CC(=O)N1CCN(C(=O)c2cccc(-c3ccccc3)c2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814753 IC50 29.0 nM
CCCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O CHEMBL194852 IC50 30.0 nM
C[C@H]1CN(C(=O)C[C@H](N)C(=O)N2Cc3ccccc3C2)CCN1C(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL1814748 IC50 32.0 nM
N#C[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)[C@@H](N)CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL3797299 IC50 36.0 nM
C[C@@H]1CN(C(=O)C[C@H](N)C(=O)N2Cc3ccccc3C2)CCN1C(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL1814749 Ki 37.0 nM
CC1CCN(C(=O)[C@@H](N)CC(=O)N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)C1 CHEMBL3799388 IC50 37.0 nM
N#Cc1ccc(N2CCN([C@@H]3CN[C@H](C(=O)N4CCSC4)C3)CC2)nc1 CHEMBL241253 IC50 40.0 nM
N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1 CHEMBL487872 IC50 43.0 nM
Cc1c(C(=O)NCC(C)(C)NCC(=O)N2CCC[C@H]2C#N)cnc2cc(-c3ccccc3)nn12 CHEMBL1929392 IC50 43.0 nM
CC(C)(C)[C@H](N)C(=O)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063032 IC50 43.0 nM
Cc1cc2nc(C)c(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1 CHEMBL1929395 IC50 45.0 nM
CCC1CCN(C(=O)[C@@H](N)CC(=O)N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)C1 CHEMBL3797358 IC50 50.0 nM
CC(C)[C@H](N)C(=O)N1CSC[C@H]1B(O)O CHEMBL510594 IC50 51.0 nM
CC(C)[C@H](N)C(=O)N1CCCC1B(O)O CHEMBL4176189 IC50 51.0 nM
N[C@@H](CCC(=O)O)C(=O)N1C[C@@H](O)C[C@H]1B(O)O CHEMBL2063029 IC50 54.0 nM
Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(O)n2n1 CHEMBL1929390 IC50 58.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)CN(CC(=O)Nc1ccnn1C)C2=O CHEMBL1910125 Ki 60.0 nM
N[C@@H](CC(=O)N1CCN(Cc2ccc3ccccc3c2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL3216066 IC50 63.0 nM
Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)cn2n1 CHEMBL1929387 IC50 68.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CC(=O)N1CCN(C(=O)c2ccccc2)CC1 CHEMBL190029 IC50 71.0 nM
N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)[C@@H](N)CCCCN CHEMBL471731 IC50 71.0 nM
CC[C@H](C)[C@H](N)C(=O)N1C[C@@H](N=[N+]=[N-])C[C@H]1C#N CHEMBL471546 IC50 72.0 nM
O=C([C@@H]1C[C@H](N2CCN(c3cc(C(F)(F)F)nc4ccccc34)CC2)CN1)N1CCSC1 CHEMBL2058971 IC50 72.4 nM
Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1 CHEMBL1929388 IC50 76.0 nM
N[C@H](C(=O)N1CCCC1)C1CCCCC1 CHEMBL278393 IC50 78.0 nM
N[C@@H](CC(=O)N1CCCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814745 IC50 80.0 nM
N[C@@H](CC(=O)N1CCN(Cc2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814747 IC50 80.0 nM
N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)[C@@H](N)CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL3797441 IC50 80.0 nM
Cc1cc(N2CCN([C@@H]3CN[C@H](C(=O)N4CCSC4)C3)CC2)n(-c2cccc(F)c2)n1 CHEMBL2147712 IC50 86.0 nM
C[C@@H](c1ccc(-c2ccc(F)cc2)cc1)[C@H](N)C(=O)N1CC[C@H](F)C1 CHEMBL237336 IC50 88.0 nM
NCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O CHEMBL194428 IC50 95.0 nM
CCC1(CC)C(=O)N(c2cccc(CN3CCN(Cc4cccc5ccccc45)CC3)c2)C1=O CHEMBL5409949 Ki 95.0 nM
CC(C)[C@H](N)C(=O)N[C@@H](C)B(O)O CHEMBL365322 Ki 96.0 nM
N#Cc1ccc(O[C@H]2CC[C@H](NCC(=O)N3CCC[C@H]3C#N)CC2)nc1 CHEMBL3085037 Ki 110.0 nM
O=C([C@@H]1CCCN1)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063034 IC50 110.0 nM
N[C@@H](CCCCNCc1ccccc1)C(=O)N1Cc2ccccc2C1 CHEMBL520200 IC50 111.0 nM
C=C1CCN(C(=O)[C@@H](N)CC(=O)N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)C1 CHEMBL3800113 IC50 113.0 nM
N[C@@H](CCCC(=O)O)C(=O)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063039 IC50 114.0 nM
C=C1C[C@@H](C#N)N(C(=O)[C@@H](N)CC(=O)N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)C1 CHEMBL3797842 IC50 119.0 nM
CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1 CHEMBL397070 IC50 120.0 nM
O=C(NC12CC3CC(C1)CC(OCc1ccc(F)cc1F)(C3)C2)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5434105 IC50 120.0 nM
N#C[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2 CHEMBL385517 Ki 130.0 nM
C[C@H](NC(=O)[C@@H](N)CCC(N)=O)B(O)O CHEMBL501506 Ki 140.0 nM
N#Cc1ccccc1-c1ccc(CN2CCN(C(=O)C[C@H](N)C(=O)N3Cc4ccccc4C3)CC2)cc1 CHEMBL1814743 IC50 141.0 nM
N[C@@H](CCCCNC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)N1CCCC1 CHEMBL505629 IC50 147.0 nM
COc1cc2c(cc1OC)CN(C(=O)CC(N)C(=O)N1Cc3ccccc3C1)CC2 CHEMBL361107 IC50 150.0 nM
CC(C)c1cc(C(=O)O)ccc1OC[C@H]1CC[C@@H](C(=O)N2CCC[C@H]2C#N)N1 CHEMBL436744 Ki 151.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2ccc(C(=O)O)cc2Cl)N1 CHEMBL379999 Ki 155.0 nM
CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1 CHEMBL502153 IC50 160.0 nM
N[C@@H](CC(=O)N1CCN(C(=O)C2c3ccccc3-c3ccccc32)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814751 IC50 166.0 nM
N[C@H](C(=O)N1CCSC1)[C@H]1CC[C@H](NC(=O)c2ccc(OC(F)(F)F)cc2)CC1 CHEMBL1682974 IC50 170.0 nM
NCCNC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5423126 IC50 170.0 nM
COc1cc2c(cc1OC)C(CCO)N(C(=O)C[C@H](N)C(=O)N1CCC[C@H]1C#N)CC2 CHEMBL193105 IC50 174.0 nM
COc1ccc(CCNC(=O)C[C@H](N)C(=O)N2CCC[C@H]2C#N)cc1OC CHEMBL191577 IC50 177.0 nM
O=C(NC(c1ccccc1)c1ccccc1)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5406353 IC50 180.0 nM
N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)[C@@H](N)CCCCN(c1cccc2ccccc12)c1cccc2ccccc12 CHEMBL518144 IC50 187.0 nM
CCCC[C@@H](NC(=O)[C@@H](N)C(C)C)B(O)O CHEMBL194250 IC50 190.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)C[C@H](N)Cc1ccc(Cl)c(Cl)c1 CHEMBL3330058 IC50 190.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2ccc(C(=O)O)c3ccccc23)N1 CHEMBL380090 Ki 191.0 nM
N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1Cc2ccccc2C1 CHEMBL488227 IC50 200.0 nM
NCCCC[C@H](N)C(=O)N1Cc2ccccc2C1 CHEMBL488226 IC50 200.0 nM
N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)c1ccccc1)Cc1cccc(Cl)c1 CHEMBL561322 IC50 200.0 nM
N#C[C@@H]1CCCN1C(=O)CNCCC(=O)N1CCN(C(=O)c2cc(F)cc(F)c2)CC1 CHEMBL372746 IC50 202.0 nM
N#C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)[C@@H](N)CCCCN(c1ccc2ccccc2c1)c1ccc2ccccc2c1 CHEMBL481466 IC50 202.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1 CHEMBL201268 IC50 210.0 nM
COc1cc2c(cc1OC)C(Cc1ccccc1)N(C(=O)C[C@H](N)C(=O)N1CCC[C@H]1C#N)CC2 CHEMBL190183 IC50 220.0 nM
CC[C@@H](C)[C@H](N)C(=O)N1CCSC1 CHEMBL191775 IC50 220.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CC(=O)N1Cc2ccccc2C1 CHEMBL522002 IC50 220.0 nM
Cc1cc(N2CCN([C@@H]3CN[C@H](C(=O)N4CCSC4)C3)CC2)n(-c2ccccn2)n1 CHEMBL2147771 IC50 220.0 nM
N[C@H]1C[C@@H](N2Cc3nc(C(F)(F)F)[nH]c3C2)CO[C@@H]1c1cc(F)ccc1F CHEMBL2425069 IC50 220.0 nM
NC(=O)c1cccc(NCC2=CC[C@H](c3cc(F)c(F)c(F)c3)[C@@H](N)C2)c1 CHEMBL274660 Ki 230.0 nM
N[C@@H](CC(=O)N1C[C@H]2C[C@@H]1CN2C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 CHEMBL3215830 IC50 230.0 nM
CO[C@@H]1C[C@H]2C[C@H](NCC(=O)N3CCC[C@H]3C#N)C[C@H]2C1 CHEMBL1082347 IC50 235.0 nM
N#Cc1ccc(OC[C@H]2CC[C@@H](C(=O)N3CCC[C@H]3C#N)N2)c(Cl)c1 CHEMBL209940 Ki 239.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCCCNC(=O)OCc1ccccc1 CHEMBL471544 IC50 240.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccc(Cl)c(Cl)c3)nn2)cc1 CHEMBL2418633 IC50 240.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)Cc1ccc(C(F)(F)F)cc1 CHEMBL3093908 IC50 240.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2cc(C(=O)O)ccc2Cl)N1 CHEMBL378867 Ki 241.0 nM
Cc1cc(N2CCN([C@@H]3CN[C@H](C(=O)N4CCSC4)C3)CC2)n(-c2ccccc2)n1 CHEMBL2147777 IC50 260.0 nM
N[C@@H](CC(=O)N1CCN(C(=O)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814752 IC50 278.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(CCc3ccccc3)nn2)cc1 CHEMBL2418637 IC50 280.0 nM
O=C([C@@H]1C[C@@H](Nc2ccc3ccccc3c2)CN1)N1Cc2ccccc2C1 CHEMBL453582 IC50 290.0 nM
COc1cccc(Cn2cc(-c3ccc(C[C@H](N)C(=O)N4CCC[C@H]4C#N)cc3)nn2)c1 CHEMBL2418630 IC50 300.0 nM
N[C@H]1CC(CN2CCc3ccccc3C2)=CC[C@@H]1c1cc(F)c(F)c(F)c1 CHEMBL216622 Ki 310.0 nM
CC(C)c1cc(C(C)C)c(S(=O)(=O)N2CCN(C(=O)C[C@H](N)C(=O)N3Cc4ccccc4C3)CC2)c(C(C)C)c1 CHEMBL1811949 IC50 310.0 nM
N[C@@H](CCC(=O)O)C(=O)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063030 IC50 320.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3cccc(Cl)c3)nn2)cc1 CHEMBL2417563 IC50 320.0 nM
N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1C(O)c1ccc(F)cc1)Cc1cc(F)c(F)cc1F CHEMBL536536 IC50 326.0 nM
CS(=O)(=O)c1ccc(OC[C@H]2CC[C@@H](C(=O)N3CCC[C@H]3C#N)N2)c(Cl)c1 CHEMBL210805 Ki 330.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccccc3F)nn2)cc1 CHEMBL2418624 IC50 330.0 nM
N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)[C@H]1Cc1ccc(F)cc1)Cc1cc(F)c(F)cc1F CHEMBL1203953 IC50 332.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN CHEMBL461912 IC50 340.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccc(Cl)cc3)nn2)cc1 CHEMBL2418628 IC50 340.0 nM
O=C(CNC12CC3CC(C1)CC(NCC(=O)N1Cc4ccccc4C1)(C3)C2)N1Cc2ccccc2C1 CHEMBL5402025 IC50 340.0 nM
CCCC[C@@H](NC(=O)[C@@H](N)CCCCN)B(O)O CHEMBL194517 IC50 350.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCCC(=O)N1Cc2ccccc2C1 CHEMBL493544 IC50 360.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCCN1Cc2ccccc2C1=O CHEMBL1243372 IC50 360.0 nM
CC[C@H](C)[C@H](N)C(=O)N1CCSC1 CHEMBL98408 IC50 364.0 nM
N#Cc1cccc(F)c1N1C[C@@H]2[C@H](C1)[C@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N CHEMBL481177 IC50 366.0 nM
COc1ccc(CC2c3nnc(C(F)(F)F)n3CCN2C(=O)C[C@H](N)Cc2cc(F)c(F)cc2F)cc1 CHEMBL539352 IC50 367.0 nM
N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2conc2C1 CHEMBL3798277 IC50 370.0 nM
CC(C)(C)NC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2 CHEMBL5398643 IC50 370.0 nM
COc1ccc2c(c1)CCN2[C@@H]1CN[C@H](C(=O)N2CCSC2)C1 CHEMBL388111 IC50 378.8 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CC(=O)NCc1ccccc1 CHEMBL365113 IC50 389.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccccc3Cl)nn2)cc1 CHEMBL2418627 IC50 390.0 nM
N#Cc1ccc(N2C[C@@H]3[C@H](C2)[C@H]3NCC(=O)N2C[C@@H](F)C[C@H]2C#N)c(Cl)c1 CHEMBL481669 IC50 399.0 nM
CCCC[C@@H](NC(=O)[C@@H](N)CC)B(O)O CHEMBL195271 IC50 400.0 nM
O=C(N[C@H]1CC[C@H](O)CC1)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5405991 IC50 400.0 nM
Cc1ccc(-c2c(CN)c(CC(C)(C)C)nc(CC(C)C)c2C(=O)O)cc1 CHEMBL3215606 IC50 420.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3cccc(F)c3)nn2)cc1 CHEMBL2418625 IC50 430.0 nM
COc1cc2c(cc1OC)C(C(C)C)N(C(=O)C[C@H](N)C(=O)N1CCC[C@H]1C#N)CC2 CHEMBL192116 IC50 439.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccc(F)cc3)nn2)cc1 CHEMBL2418626 IC50 440.0 nM
COc1ccc(Cn2cc(-c3ccc(C[C@H](N)C(=O)N4CCC[C@H]4C#N)cc3)nn2)cc1 CHEMBL2418631 IC50 450.0 nM
CN(C)C(=O)[C@@H](c1ccc(-c2cccc(C#N)c2)cc1)[C@H](N)C(=O)N1CC[C@H](F)C1 CHEMBL190269 IC50 460.0 nM
COc1ccc(Cn2cc(-c3ccc(C[C@H](N)C(=O)N4CCC[C@H]4C#N)cc3)nn2)cc1OC CHEMBL2418634 IC50 470.0 nM
N[C@@H](CCCCN(c1ccc2ccccc2c1)c1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1 CHEMBL488047 IC50 479.0 nM
C[C@H](N)C(=O)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063025 IC50 480.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)C[C@H](N)Cc1ccccc1Cl CHEMBL3330050 IC50 490.0 nM
CC(=O)c1ccc(N2C[C@@H]3[C@H](C2)[C@H]3NCC(=O)N2C[C@@H](F)C[C@H]2C#N)cc1 CHEMBL480914 IC50 500.0 nM
O=C1N[C@H](C(=O)N2CCC[C@H]2B(O)O)C[C@H]1CC(=O)N1Cc2ccccc2C1 CHEMBL1243184 IC50 500.0 nM
O=C([C@@H]1C[C@@H](O)CN1)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063036 IC50 500.0 nM
C[C@H](N)C(=O)N1CC(=O)C[C@H]1B(O)O CHEMBL2063027 IC50 510.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3cccs3)nn2)cc1 CHEMBL2418639 IC50 510.0 nM
O=C(NCc1ccccc1)NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5437013 IC50 510.0 nM
N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1CCSC1 CHEMBL461092 IC50 520.0 nM
N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)C(=O)C1)C(=O)N1Cc2ccccc2C1 CHEMBL3216276 IC50 520.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1cccc(C(F)(F)F)c1 CHEMBL3093901 IC50 520.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(N)cc1 CHEMBL3093921 IC50 520.0 nM
CC(=O)Nc1ccc(OP(=O)(Oc2ccc(NC(C)=O)cc2)C2c3ccccc3CN2C(=O)[C@@H](N)CCCCN)cc1 CHEMBL440982 IC50 530.0 nM
CCOC(=O)CNC(=O)c1ccc(OP(=O)(Oc2ccc(C(=O)NCC(=O)OCC)cc2)C2CCCN2C(=O)C2CCCN2)cc1 CHEMBL235766 IC50 530.0 nM
O=C([C@@H]1C[C@H](N2CCN(c3ccc(C(F)(F)F)cn3)CC2)CN1)N1CCC(F)(F)C1 CHEMBL474410 IC50 530.0 nM
O=C([C@@H]1C[C@H](O)CN1)N1C[C@H](O)C[C@H]1B(O)O CHEMBL2063038 IC50 530.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2cc(C(=O)O)cnc2Cl)N1 CHEMBL377296 Ki 538.0 nM
O=C([C@@H]1C[C@H](N2CCN(c3cnccn3)CC2)CN1)N1CCC(F)(F)C1 CHEMBL474409 IC50 540.0 nM
CC[C@@H](C)[C@H](N)C(=O)N1CCCC1 CHEMBL453573 IC50 550.0 nM
N[C@@H](CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1CCC(C(F)(F)F)C1 CHEMBL3798691 IC50 550.0 nM
NC(CC(=O)N1CCc2ccccc2C1)C(=O)N1Cc2ccccc2C1 CHEMBL179845 IC50 555.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)CN(CC(=O)NCc1cccnc1)C2=O CHEMBL1910126 Ki 558.0 nM
NC(=O)c1cccc(OCC2=CC[C@H](c3cc(F)c(F)c(F)c3)[C@@H](N)C2)c1 CHEMBL410514 Ki 560.0 nM
O=C([C@@H]1C[C@H](N2CCc3cc(F)ccc32)CN1)N1CCSC1 CHEMBL223914 IC50 562.8 nM
NC12CC3CC(C1)CC(NC(=O)OC14CC5CC(CC(NCC(=O)N6Cc7ccccc7C6)(C5)C1)C4)(C3)C2 CHEMBL5399390 IC50 570.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5400525 IC50 590.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)C[C@H](N)Cc1ccccc1 CHEMBL3330049 IC50 600.0 nM
CC(C)(C)OC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5cc(F)c(F)cc5C4)(C3)C1)C2 CHEMBL5402430 IC50 600.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2ccccc2Cl)N1 CHEMBL377390 Ki 616.0 nM
N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1Cc1ccccc1)Cc1cc(F)c(F)cc1F CHEMBL539350 IC50 622.0 nM
CCCc1nc(CC(C)(C)C)c(CN)c(-c2ccc(C)cc2)c1C(=O)O CHEMBL3215820 IC50 630.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1cccc(F)c1 CHEMBL3093917 IC50 630.0 nM
N#Cc1ccc(N2C[C@@H]3[C@H](C2)[C@H]3NCC(=O)N2C[C@@H](F)C[C@H]2C#N)c(F)c1 CHEMBL479381 IC50 637.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)C[C@H](N)Cc1ccc(I)cc1 CHEMBL3330054 IC50 640.0 nM
N#Cc1ccc(CCC(=O)NC23CC4CC(CC(NCC(=O)N5Cc6ccccc6C5)(C4)C2)C3)cc1 CHEMBL5401924 IC50 640.0 nM
N#Cc1ccc(N2C[C@@H]3[C@H](C2)[C@H]3NCC(=O)N2C[C@@H](F)C[C@H]2C#N)c(C(F)(F)F)c1 CHEMBL481288 IC50 652.0 nM
N[C@@H](CCCCN(Cc1ccccc1)Cc1ccccc1)C(=O)N1Cc2ccccc2C1 CHEMBL487871 IC50 666.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)C[C@H](N)Cc1ccc(Cl)cc1Cl CHEMBL3330057 IC50 670.0 nM
O=C(NC(c1ccc(F)cc1)c1ccc(F)cc1)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5408720 IC50 670.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)CN(c1ccc(C#N)cc1)C2=O CHEMBL1910108 Ki 675.0 nM
N#Cc1ccc(CN[C@@H]2CN[C@H](C(=O)N3CCSC3)C2)cc1 CHEMBL223497 IC50 678.9 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccccc3)nn2)cc1 CHEMBL2418636 IC50 680.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)C[C@H](N)Cc1ccc(F)cc1 CHEMBL3330053 IC50 680.0 nM
COc1ccc(N2Cc3c(nc(C)c(CN)c3-c3ccc(Cl)cc3Cl)C2=O)cc1 CHEMBL1909989 Ki 688.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(-c2cn(Cc3ccc(F)c(F)c3)nn2)cc1 CHEMBL2418632 IC50 690.0 nM
N[C@@H](CC(=O)N1CCC[C@H]1CNS(=O)(=O)c1ccccc1)Cc1ccccc1F CHEMBL539187 IC50 700.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)Cc1csc(-c2cccs2)n1 CHEMBL3127991 IC50 700.0 nM
O=C([C@@H]1C[C@H](Nc2cccc3ccccc23)CN1)N1Cc2ccccc2C1 CHEMBL527647 IC50 710.0 nM
Cc1ccccc1C[C@@H](N)CC(=O)N1C[C@@H](F)C[C@H]1C#N CHEMBL3330051 IC50 710.0 nM
N[C@@H](CC(=O)N1CCC(N2CCCCC2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814756 IC50 730.0 nM
O=C([C@@H]1C[C@H](N2CCc3ccccc32)CN1)N1CCSC1 CHEMBL389244 IC50 736.5 nM
CC(=O)OC[C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F CHEMBL3357769 IC50 750.0 nM
CC[C@@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1 CHEMBL488105 IC50 800.0 nM
NCCCCNC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5439059 IC50 800.0 nM
O=C(NCc1ccc(F)cc1F)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5401877 IC50 800.0 nM
CC(C)(C)OC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2 CHEMBL5421476 IC50 800.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)CN(CC(=O)N1CCCC1)C2=O CHEMBL1910123 Ki 802.0 nM
Cc1nnc(C(=O)[C@@H]2CCCN2C(=O)CNC23CC4CC(CC(C4)C2)C3)o1 CHEMBL232725 IC50 808.0 nM
CCc1nc(CC(C)(C)C)c(CN)c(-c2ccc(C)cc2)c1C(=O)O CHEMBL3216719 IC50 820.0 nM
CCN(CC)C(=O)CN1Cc2c(nc(C)c(CN)c2-c2ccc(Cl)cc2Cl)C1=O CHEMBL1910118 Ki 823.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCC(=O)N1CCc2ccccc2C1 CHEMBL494146 IC50 830.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)CN[C@H]1[C@@H]2CN(c3ccccn3)C[C@@H]21 CHEMBL511125 IC50 837.0 nM
N#C[C@@H]1CCCN1C(=O)CNCCC(=O)Nc1ccccc1 CHEMBL371480 IC50 855.0 nM
C[C@H](NC(=O)[C@@H](N)CCC(=O)O)B(O)O CHEMBL447366 Ki 880.0 nM
N[C@@H](CC(=O)N1[C@H](COC(=O)C2CC2)C[C@@H]2CCCC[C@@H]21)Cc1cc(F)c(F)cc1F CHEMBL3357770 IC50 880.0 nM
COc1ccccc1N1Cc2c(nc(C)c(CN)c2-c2ccc(Cl)cc2Cl)C1=O CHEMBL1909991 Ki 886.0 nM
O=C(NC12CC3CC(CC(O)(C3)C1)C2)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5394582 IC50 890.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(Br)cc1 CHEMBL3093896 IC50 900.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)Cc1csc(-c2ccccc2)n1 CHEMBL3127988 IC50 900.0 nM
[N-]=[N+]=NCCCNC(=O)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5431503 IC50 900.0 nM
CC(=O)Nc1ccc(OP(=O)(Oc2ccc(NC(C)=O)cc2)C2CCCN2C(=O)[C@@H](N)CCCCN)cc1 CHEMBL236781 IC50 910.0 nM
O=C([C@@H]1C[C@H](Nc2ccc3ccccc3c2)CN1)N1Cc2ccccc2C1 CHEMBL488493 IC50 910.0 nM
N[C@@H](CC(=O)N1CCC[C@H]1C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1Cc2ccccc2C1 CHEMBL1814755 IC50 910.0 nM
CC(C)(CO)NCC(=O)N1CCC[C@H]1C(=O)c1nnc(C(C)(C)C)o1 CHEMBL232759 IC50 930.0 nM
N[C@H](C(=O)N1CCSC1)[C@H]1CC[C@H](NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1 CHEMBL25211 IC50 930.0 nM
N[C@@H](CCC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2ccccc2C1 CHEMBL1814634 IC50 960.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(Cl)cc1 CHEMBL3093925 IC50 960.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)Cc1ccc(F)cc1F CHEMBL3093913 IC50 960.0 nM
Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)CN(CC(=O)N1CCOCC1)C2=O CHEMBL1910124 Ki 967.0 nM
O=C([C@@H]1C[C@H](N2CCN(c3nc4ccncc4o3)CC2)CN1)N1CCC(F)(F)C1 CHEMBL475573 IC50 970.0 nM
N[C@@H](CC(=O)N1CCn2c(nnc2-c2ccc(F)cc2)C1)Cc1cc(F)ccc1F CHEMBL233472 IC50 979.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCC(=O)N1CCN(c2ccncc2)CC1 CHEMBL474982 IC50 980.0 nM
N[C@H](C(=O)N1CC[C@H](F)C1)C1CCC(NS(=O)(=O)c2ccc(F)cc2F)CC1 CHEMBL395213 IC50 990.0 nM
N[C@H](C(=O)N1CC[C@H](F)C1)[C@H]1CC[C@H](NS(=O)(=O)c2ccc(F)cc2F)CC1 CHEMBL22310 IC50 993.0 nM
CC(=O)N1CCN(C(=O)CN2Cc3c(nc(C)c(CN)c3-c3ccc(Cl)cc3Cl)C2=O)CC1 CHEMBL1910120 Ki 993.0 nM
CCCC[C@@H](NC(=O)[C@@H](N)CCCC)B(O)O CHEMBL194249 IC50 1000.0 nM
N[C@H]1CN(Cc2ccc(-c3csnn3)cc2)C[C@H]1C(=O)N1CCCC1 CHEMBL250611 IC50 1000.0 nM
CC(C)(CC(=O)N1CCc2ccccc2C1)[C@H](N)C(=O)N1CCC[C@H]1C#N CHEMBL474025 IC50 1000.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H](N)CCC(=O)N1CCc2nc(-c3ccc(F)cc3)sc2C1 CHEMBL494339 IC50 1000.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)Cc1csc(-c2ccc(Cl)cc2)n1 CHEMBL3127989 IC50 1000.0 nM
O=C(NCCCc1ccccc1)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5422425 IC50 1000.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2 CHEMBL5408398 IC50 1000.0 nM
O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2)OCC1c2ccccc2-c2ccccc21 CHEMBL5400483 IC50 1000.0 nM