Cc1c(C(=O)N2CCN(C(=O)c3ccc(Br)cc3)[C@@H](c3ccc(Cl)cc3)C2)cnn1-c1cccc(C#N)c1 CHEMBL4073833 Kd 43.0 nM
N#Cc1cccc(-c2cc(C(=O)N3CCN(C(=O)c4ccc(Br)cn4)[C@@H](c4ccc(Cl)cc4)C3)c[nH]c2=O)c1 CHEMBL4162764 IC50 50.0 nM
O=C(c1cnn2cc(Br)ccc12)N1CCN(C(=O)c2ccc(Br)cc2)[C@@H](c2ccc(Cl)cc2)C1 CHEMBL4070071 Kd 57.0 nM
CC(C)c1cc(Cl)c2cc(C(=O)O)[nH]c2c1F CHEMBL4070102 Kd 62.0 nM
Cn1cc(C(=O)N2CCN(C(=O)c3ccc(Br)cn3)[C@@H](c3ccc(Cl)cc3)C2)cc(-c2cccc(C#N)c2)c1=O CHEMBL4170030 IC50 100.0 nM
O=C(c1cc(-c2cccc(C(F)(F)F)c2)c(=O)n(-c2ccccc2)c1)N1CCN(C(=O)c2ccc(Br)cn2)[C@@H](c2ccc(Cl)cc2)C1 CHEMBL4175313 IC50 140.0 nM
N#Cc1cccc(-c2cc(C(=O)N3CCN(C(=O)c4ccc(Cl)cc4)C(c4ccc(Cl)cc4)C3)c[nH]c2=O)c1 CHEMBL4176393 IC50 190.0 nM
O=C(c1cnn2cc(Br)ccc12)N1CCN(C(=O)c2ccc(Br)cn2)[C@@H](c2ccc(Cl)cc2)C1 CHEMBL4168783 IC50 280.0 nM
O=C(c1c[nH]c(=O)c2ccccc12)N1CCN(C(=O)c2ccc(Br)cc2)[C@@H](c2ccc(Cl)cc2)C1 CHEMBL4173010 IC50 290.0 nM
O=C(c1c[nH]c(=O)c(-c2cccc(Cl)c2)c1)N1CCN(C(=O)c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4172770 IC50 290.0 nM
N#Cc1cccc(-c2ncc(C(=O)N3CCN(C(=O)c4ccc(Br)cc4)C(c4ccc(Cl)cc4)C3)o2)c1 CHEMBL4104965 IC50 360.0 nM
N#Cc1ccnc(-c2ncc(C(=O)N3CCN(C(=O)c4ccc(Br)cc4)C(c4ccc(Cl)cc4)C3)o2)c1 CHEMBL4080736 IC50 390.0 nM
O=C(c1c[nH]c(=O)c(-c2ccccc2)c1)N1CCN(C(=O)c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4169616 IC50 410.0 nM
O=C(c1cnn2cc(Br)ccc12)N1CCN(C(=O)c2ccc(Br)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4061398 IC50 420.0 nM
O=C(c1c[nH]c(=O)c(-c2ccccc2Cl)c1)N1CCN(C(=O)c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4164548 IC50 420.0 nM
CS(=O)(=O)c1cccc(-c2cc(C(=O)N3CCN(C(=O)c4ccc(Cl)cc4)C(c4ccc(Cl)cc4)C3)c[nH]c2=O)c1 CHEMBL4176581 IC50 490.0 nM
Cc1c(C(=O)N2CCN(C(=O)c3ccc(Br)cc3)C(c3ccc(Cl)cc3)C2)cnn1-c1cccc(C#N)c1 CHEMBL4097260 IC50 580.0 nM
N#Cc1cccc(-c2ncc(C(=O)N3CCN(C(=O)c4ccc(Cl)cc4)C(c4ccc(Cl)cc4)C3)o2)c1 CHEMBL4087208 IC50 600.0 nM
O=C(c1cnc(-c2ccccc2)o1)N1CCN(C(=O)c2ccc(Br)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4070582 IC50 660.0 nM
O=C(c1c[nH]c(=O)c(-c2cccc(C(F)(F)F)c2)c1)N1CCN(C(=O)c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4168400 IC50 700.0 nM
O=C(c1cnn2cc(Br)ccc12)N1CCN(C(=O)c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4092418 IC50 720.0 nM
Cn1cc(C(=O)N2CCN(C(=O)c3ccc(Br)cn3)[C@@H](c3ccc(Cl)cc3)C2)cc(-c2cccc(C(F)(F)F)c2)c1=O CHEMBL4159400 IC50 750.0 nM
O=C(c1cnn2ccc(Br)cc12)N1CCN(C(=O)c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)C1 CHEMBL4071622 IC50 830.0 nM
COc1ccc2c(C(=O)N3CCN(C(=O)c4ccc(Br)cc4)C(c4ccc(Cl)cc4)C3)cnn2c1 CHEMBL4088472 IC50 920.0 nM