CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)C(F)(F)[C@@H]2F CHEMBL4453227 EC50 4.0 nM
N#Cc1cc(F)cc(Oc2ccc(S(=O)(=O)C(F)F)c3c2CC(F)(F)[C@H]3O)c1 CHEMBL4165848 EC50 6.0 nM
N#Cc1cc(F)cc(Oc2ccc(S(=O)(=O)CF)c3c2CC(F)(F)[C@H]3O)c1 CHEMBL4162398 EC50 9.0 nM
CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)[C@H](F)[C@@H]2F CHEMBL4585668 IC50 9.0 nM
N#Cc1cc(F)cc(Oc2ccc(S(=O)(=O)C(F)F)c3c2CC(F)(F)C3O)c1 CHEMBL4161350 IC50 10.0 nM
N#Cc1cc(F)cc(Oc2ccc3c(c2C(F)F)[C@@H](O)C(F)(F)S3(=O)=O)c1 CHEMBL4175320 EC50 10.0 nM
O=S1(=O)c2ccc(Oc3cc(F)cc(F)c3)c(C(F)F)c2C(O)C1(F)F CHEMBL4168513 IC50 11.0 nM
CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL4173075 IC50 12.0 nM
N#Cc1cc(F)cc(Oc2ccc3c(c2C(F)F)C(O)C(F)(F)S3(=O)=O)c1 CHEMBL4163990 IC50 14.0 nM
O=[N+]([O-])c1cc(S(=O)(=O)C(F)F)ccc1Nc1cc(F)cc(Cl)c1 CHEMBL4176537 IC50 16.0 nM
O=S1(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(C(F)F)c2C(O)C1(F)F CHEMBL4165091 EC50 17.0 nM
O=S1(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(Cl)c2C(O)C1(F)F CHEMBL4168978 IC50 20.0 nM
Cc1c(Oc2cc(F)cc(Cl)c2)ccc2c1C(O)C(F)(F)S2(=O)=O CHEMBL4161060 IC50 20.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c2c1C(O)C(F)(F)C2)C(F)F CHEMBL4169277 EC50 20.0 nM
Fc1cc(Br)cc([C@@H]2C[C@H](c3cccc(Br)c3)n3nnnc3N2)c1 CHEMBL3597786 Kd 23.0 nM
Fc1cc(Br)cc(C2CC(c3cccc(Br)c3)n3nnnc3N2)c1 CHEMBL3597689 Kd 28.0 nM
CCS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL4159016 IC50 31.0 nM
Fc1ccc(Br)c(F)c1[C@H]1C[C@@H](c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597782 IC50 32.0 nM
O=[N+]([O-])c1cc(S(=O)(=O)C(F)(F)F)ccc1Oc1cc(F)cc(Cl)c1 CHEMBL4168279 IC50 32.0 nM
N#Cc1cc(S(=O)(=O)C(F)(F)F)ccc1Oc1cc(F)cc(Cl)c1 CHEMBL4174407 IC50 34.0 nM
O=S(=O)(c1ccc(Oc2cncc(Cl)c2)c2c1[C@H](O)C(F)(F)C2)C(F)F CHEMBL4167415 EC50 37.0 nM
Fc1c(Cl)cccc1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597680 Kd 38.0 nM
CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)[C@H](F)C2 CHEMBL4169671 EC50 39.0 nM
O=S1(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(Br)c2C(O)C1(F)F CHEMBL4165557 EC50 43.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c(Cl)c1CO)C(F)F CHEMBL4164468 IC50 46.0 nM
Fc1ccc(Br)c(F)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597685 Kd 49.0 nM
N#Cc1c(Oc2cc(F)cc(Cl)c2)ccc2c1C(O)C(F)(F)S2(=O)=O CHEMBL4167486 IC50 49.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(Cl)c2)c2c1[C@H](O)C(F)(F)CC2 CHEMBL5417823 Kd 49.0 nM
CS(=O)(=O)c1sc(-c2ccc(C#N)c(F)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL4637022 IC50 50.0 nM
CS(=O)(=O)c1sc(-c2cc(Cl)cc(C#N)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL4641092 IC50 50.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c(Br)c1CO)C(F)F CHEMBL4172344 IC50 55.0 nM
Brc1cccc([C@@H]2C[C@H](c3cccc(Br)c3)n3nnnc3N2)c1 CHEMBL3597698 Kd 63.0 nM
CS(=O)(=O)c1sc(-c2cc(Cl)cc(C#N)c2)c2c1[C@H](O)C(F)(F)CC2 CHEMBL5427105 Kd 69.0 nM
Brc1cccc(C2CC(c3cccc(Br)c3)n3nnnc3N2)c1 CHEMBL3597676 Kd 70.0 nM
Fc1ccc(Cl)c(F)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597683 Kd 85.0 nM
Fc1c(Br)ccc(Cl)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597687 Kd 85.0 nM
Clc1ccc(Br)cc1[C@H]1C[C@@H](c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597780 IC50 87.0 nM
O=[N+]([O-])c1c(Nc2cc(F)cc(Cl)c2)ccc2nonc12 CHEMBL2311933 Kd 90.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(Cl)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5414407 Kd 91.0 nM
Fc1cc(Br)cc([C@@H]2C[C@H](c3ccccc3)n3nnnc3N2)c1 CHEMBL3597784 IC50 97.0 nM
O=S1(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(C(F)(F)F)c2C(O)C1(F)F CHEMBL4175707 EC50 100.0 nM
Brc1cccc(C2CC(c3cccc(I)c3)n3nnnc3N2)c1 CHEMBL3597677 Kd 103.0 nM
Brc1cccc([C@@H]2C[C@H](c3cccc(I)c3)n3nnnc3N2)c1 CHEMBL3597778 IC50 108.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c2c1[C@H](O)CC2)C(F)F CHEMBL4172666 EC50 110.0 nM
Clc1cccc(C2CC(c3cccc(Br)c3)Nc3nnnn32)c1 CHEMBL3597675 Kd 116.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(Cl)c2)c2c1[C@H](O)[C@H](F)C2 CHEMBL5440288 Kd 120.0 nM
Clc1ccc(Br)cc1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597679 Kd 126.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c(Cl)c1)C(F)(F)F CHEMBL4162878 IC50 140.0 nM
N#Cc1cncc(Oc2ccc3c(c2C(F)F)C(O)C(F)(F)S3(=O)=O)c1 CHEMBL4167439 IC50 140.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(C#N)c2)c2c1[C@H](O)C(F)(F)CC2 CHEMBL5398227 Kd 140.0 nM
Fc1ccc(I)cc1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597678 Kd 159.0 nM
O=[N+]([O-])c1c(Nc2cccc(Cl)c2)ccc2nonc12 CHEMBL2311959 Kd 160.0 nM
CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)CC2 CHEMBL4437382 IC50 160.0 nM
O=[N+]([O-])c1c(Nc2ccc(Cl)c(Cl)c2)ccc2nonc12 CHEMBL2311932 Kd 170.0 nM
O=[N+]([O-])c1c(Nc2ccc(Cl)c(C(F)(F)F)c2)ccc2nonc12 CHEMBL2311967 Kd 170.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c(Br)c1)C(F)(F)F CHEMBL4173593 IC50 170.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c(Br)c1)C(F)F CHEMBL4164152 IC50 180.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c2c1C(O)CC2)C(F)F CHEMBL4160209 EC50 180.0 nM
Fc1c(Cl)ccc(Cl)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597684 Kd 194.0 nM
Clc1ccccc1[C@H]1C[C@@H](c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597696 IC50 195.0 nM
CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)C[C@@H]2F CHEMBL4467490 IC50 210.0 nM
Fc1cc(Br)cc(C2CC(c3ccccc3)n3nnnc3N2)c1 CHEMBL3597688 Kd 216.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c(C(F)F)c1)C(F)(F)F CHEMBL4167600 IC50 220.0 nM
Fc1c(Br)ccc(Br)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597686 Kd 240.0 nM
Brc1cccc([C@@H]2C[C@H](c3ccccc3)n3nnnc3N2)c1 CHEMBL3597690 IC50 248.0 nM
O=[N+]([O-])c1cc(S(=O)(=O)CF)ccc1Nc1cc(F)cc(Cl)c1 CHEMBL4172030 IC50 280.0 nM
O=[N+]([O-])c1cc(C(F)(F)F)ccc1Nc1cc(F)cc(Cl)c1 CHEMBL4175480 IC50 280.0 nM
Brc1cccc([C@@H]2C[C@H](c3ccccc3Br)n3nnnc3N2)c1 CHEMBL3597694 IC50 314.0 nM
Fc1ccccc1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597671 Kd 327.0 nM
O=S1(=O)c2ccc(Oc3cncc(Cl)c3)c(C(F)F)c2C(O)C1(F)F CHEMBL4171869 IC50 350.0 nM
CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)[C@@H](F)C2 CHEMBL4170809 IC50 350.0 nM
CS(=O)(=O)c1sc(-c2ccc(F)c(F)c2)c2c1[C@H](O)C(F)(F)CC2 CHEMBL5397307 Kd 360.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(C#N)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5394054 Kd 360.0 nM
Clc1ccccc1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597673 Kd 361.0 nM
O=[N+]([O-])c1c(Nc2cc(F)cc(C(F)(F)F)c2)ccc2nonc12 CHEMBL2311930 Kd 370.0 nM
Fc1ccc(F)c(C2CC(c3cccc(Br)c3)Nc3nnnn32)c1F CHEMBL3597681 Kd 393.0 nM
O=[N+]([O-])c1c(Nc2ccc(F)c(Cl)c2)ccc2nonc12 CHEMBL2311966 Kd 400.0 nM
Brc1cccc(C2CC(c3ccccc3Br)n3nnnc3N2)c1 CHEMBL3597672 Kd 400.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(F)c2)c2c1[C@H](O)C(F)(F)CC2 CHEMBL5439202 Kd 400.0 nM
Fc1ccc(Br)c(Cl)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 CHEMBL3597682 Kd 411.0 nM
O=S(=O)(c1ccc(Oc2cc(F)cc(Cl)c2)c2c1[C@@H](O)CC2)C(F)F CHEMBL4164767 IC50 460.0 nM
COc1cc(Nc2nsc3ccccc23)cc(OC)c1 CHEMBL4869108 EC50 490.0 nM
CS(=O)(=O)c1sc(-c2ccc(F)cc2)c2c1[C@H](O)C(F)(F)CC2 CHEMBL5433232 Kd 490.0 nM
O=[N+]([O-])c1c(NCc2ccc(F)cc2Cl)ccc2nonc12 CHEMBL2311947 Kd 500.0 nM
O=[N+]([O-])c1c(NCc2ccc(F)cc2C(F)(F)F)ccc2nonc12 CHEMBL2311951 Kd 540.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(F)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL4639113 Kd 560.0 nM
O=[N+]([O-])c1c(Nc2cccc(C(F)(F)F)c2)ccc2nonc12 CHEMBL2311960 Kd 640.0 nM
CS(=O)(=O)c1sc(-c2cc(F)cc(Cl)c2)c2c1[C@H](O)[C@@H](F)C2 CHEMBL5395791 Kd 650.0 nM
Nc1nccc(-c2c3c(O)ccnc3n3c(N)nccc23)n1 CHEMBL380500 EC50 700.0 nM
NCc1c(S(=O)(=O)C(F)F)ccc(Oc2cc(F)cc(Cl)c2)c1Br CHEMBL4169518 IC50 700.0 nM
O=[N+]([O-])c1c(Nc2cc(F)cc(F)c2)ccc2nonc12 CHEMBL2311931 Kd 730.0 nM
Brc1cccc(C2CC(c3ccccc3I)n3nnnc3N2)c1 CHEMBL3597670 Kd 766.0 nM
CS(=O)(=O)c1sc(-c2cccc(C#N)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5417825 Kd 820.0 nM
CS(=O)(=O)c1sc(-c2ccc(F)cc2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5420728 Kd 830.0 nM
CS(=O)(=O)c1sc(-c2ccc(F)c(F)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5399126 Kd 830.0 nM
Clc1ccccc1C1CC(c2cccc(I)c2)Nc2nnnn21 CHEMBL3597674 Kd 837.0 nM
CS(=O)(=O)c1sc(Oc2cc(F)cc(F)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5404562 Kd 880.0 nM
Brc1cccc(C2CC(c3ccccc3)n3nnnc3N2)c1 CHEMBL1401692 Kd 883.0 nM
CS(=O)(=O)c1sc(Oc2cc(F)cc(C#N)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5431351 Kd 960.0 nM
Ic1cccc([C@@H]2C[C@H](c3ccccc3)n3nnnc3N2)c1 CHEMBL3597692 IC50 1000.0 nM
CS(=O)(=O)c1sc(Oc2cccc(F)c2)c2c1[C@H](O)C(F)(F)C2 CHEMBL5412171 Kd 1000.0 nM