Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 CHEMBL400402 Kd apparent 2.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C CHEMBL3752910 IC50 6.0 nM
Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1 CHEMBL5416410 Kd 6.9 nM
Cc1ccc(O)cc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL3321809 IC50 7.0 nM
Cc1ccc(O)c(Cl)c1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL5191665 IC50 7.0 nM
Cc1ccc(O)cc1-n1c(N)c(C(N)=O)c2cc3ccccc3nc21 CHEMBL5203261 IC50 7.0 nM
COc1ccccc1-n1c(-c2cc(O)ccc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL566515 IC50 15.0 nM
Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL5202826 IC50 18.0 nM
Cc1ccc(C(=O)Nc2ccc(CN3Cc4cn[nH]c4C3)c(Cl)c2)cc1C#Cc1cnc2cccnn12 CHEMBL4638981 IC50 19.5 nM
Cc1ccc(C(=O)Nc2ccc(CN3CCC4C=NNC4C3)c(Cl)c2)cc1C#Cc1cnc2cccnn12 CHEMBL4640297 IC50 50.5 nM
O=C(Nc1ccccc1Cl)c1cnc2ccc(-c3ccccc3)cn12 CHEMBL1078739 IC50 60.0 nM
O=C(Nc1ccccc1Cl)c1cnn2ccc(N3CCCCC3)cc12 CHEMBL1078214 IC50 63.0 nM
O=C(Nc1ccccc1Cl)c1cnn2ccc(-c3ccccc3)cc12 CHEMBL1078107 IC50 66.0 nM
CN(C)c1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1 CHEMBL1077571 IC50 77.0 nM
O=C(Nc1ccccc1Cl)c1cnc2ccc(C3CCNCC3)cn12 CHEMBL1077739 IC50 79.0 nM
Cc1ccc(O)cc1Nc1ccnc(Nc2cccc(C(N)=O)c2)n1 CHEMBL249097 Kd 81.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Kd 85.0 nM
O=C(Nc1ccccc1Cl)c1cnc2ccc(N3CCCCC3)cn12 CHEMBL1078840 IC50 87.0 nM
Cc1nc2ccc(Br)cn2c1C(=O)Nc1ccccc1Cl CHEMBL1077741 IC50 173.0 nM
CO[C@@H](C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 CHEMBL402548 Kd apparent 175.0 nM
COc1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1 CHEMBL1080959 IC50 190.0 nM
O=C(Nc1ccccc1Cl)c1cnn2ccc(-n3cccc3)cc12 CHEMBL1078108 IC50 200.0 nM
COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl CHEMBL288441 Kd 210.0 nM
O=C(Nc1ccccc1Cl)c1cnc2ccc(C3(O)CCNCC3)cn12 CHEMBL1077740 IC50 228.0 nM
O=C(Nc1ccccc1Cl)c1cnn2ccc(N3CCOCC3)cc12 CHEMBL1078109 IC50 240.0 nM
Cc1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1 CHEMBL1081498 IC50 260.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 340.0 nM
Cc1ccccc1Nc1nc2cc(F)c(N(C)C(=O)/C=C/CN(C)C)cc2n2cncc12 CHEMBL1916891 IC50 350.0 nM
O=C(Nc1ccccc1Cl)c1cnc2ccccn12 CHEMBL1078738 IC50 460.0 nM
Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12 CHEMBL1171837 Kd apparent 547.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 741.0 nM
O=C(Nc1ccccc1Cl)c1cnn2ccccc12 CHEMBL1078785 IC50 1000.0 nM
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1 CHEMBL255863 Kd 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM