Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(F)c5)CC4)cc3)c12 CHEMBL4100979 IC50 0.13 nM
Cn1cc(-c2ccc(Cn3cc(-c4ccccc4F)nn3)cc2)cn1 CHEMBL4469077 IC50 0.16 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 IC50 0.2 nM
Fc1ccccc1-c1cn(Cc2ccc(-c3cncnc3)cc2)nn1 CHEMBL4459732 IC50 0.25 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(Br)cc(C(F)(F)F)c4)cc3)cc2n1 CHEMBL4069517 IC50 0.27 nM
c1ccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)cc1 CHEMBL4456738 IC50 0.32 nM
Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1 CHEMBL5416410 Kd 0.34 nM
Nc1ncc(-c2cccc(S(N)(=O)=O)c2)c2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL241682 IC50 0.4 nM
Cc1ccc(-c2cn(Cc3ccc(-c4cccnc4)cc3)nn2)cc1 CHEMBL4519953 IC50 0.44 nM
CN(c1ccnc(Nc2cc(N3CCOCC3)nc(N3CCOCC3)c2)n1)c1cccc2[nH]ncc12 CHEMBL1270280 IC50 0.9 nM
Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 CHEMBL400402 Kd apparent 0.9 nM
CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(S(N)(=O)=O)c1 CHEMBL496760 IC50 1.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc6c(c5)OCO6)CC4)cc3)c12 CHEMBL4101918 IC50 1.26 nM
CN(c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1)c1cccc2[nH]ncc12 CHEMBL1269858 IC50 1.3 nM
Cn1cc(-c2ccc(Cn3cc(-c4ccccc4)nn3)cc2)cn1 CHEMBL4453627 IC50 1.49 nM
COc1ccccc1-n1c(-c2cc(O)ccc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL566515 IC50 1.6 nM
CS(=O)(=O)c1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(N2CCOCC2)c1 CHEMBL497198 IC50 2.0 nM
CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(N2CCOCC2)c1 CHEMBL523744 IC50 2.0 nM
Clc1ccc2c(c1Nc1ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n1)OCO2 CHEMBL468970 IC50 2.0 nM
Cc1ccc(CO)cc1N(c1ccnc(Nc2cc(N3CCOCC3)cc(S(C)(=O)=O)c2)n1)C(C)C CHEMBL1738764 IC50 2.0 nM
COc1cncc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762535 IC50 2.0 nM
CN(c1ccc(Cl)c(CO)c1)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762531 IC50 2.0 nM
COc1cc(CO)cc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762529 IC50 2.0 nM
COc1cccc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762525 IC50 2.0 nM
CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O CHEMBL4291811 Kd 2.0 nM
Cc1ccc(-c2cn(Cc3ccc(-c4cnn(C)c4)cc3)nn2)cc1 CHEMBL4543212 IC50 2.13 nM
Cn1cc(-c2ccc(Cn3cc(-c4ccc(C(F)(F)F)cc4)nn3)cc2)cn1 CHEMBL4525897 IC50 2.21 nM
CN(c1ccnc(Nc2cc(N3CCOCC3)nc(N3CCOCC3)n2)n1)c1cccc2[nH]ncc12 CHEMBL1270378 IC50 2.6 nM
COc1ccc(-c2ccc(Cn3cc(-c4cccc(N)c4)nn3)cc2)cn1 CHEMBL4441465 IC50 2.99 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(S(C)(=O)=O)c2)n1 CHEMBL1762546 IC50 3.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C CHEMBL3752910 IC50 3.0 nM
Cc1ccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)cc1 CHEMBL4452405 IC50 3.3 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(OC(F)(F)F)cc5Br)CC4)cc3)c12 CHEMBL4071731 IC50 3.6 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)cn1 CHEMBL4171543 IC50 3.87 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1N1Cc2cnc(N)nc2N(C)C1=O CHEMBL459850 EC50 4.0 nM
CCN(c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1)c1cc(CO)ccc1C CHEMBL1762547 IC50 4.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCN(C)CC3)c2)n1 CHEMBL1762539 IC50 4.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762530 IC50 4.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Br)cc5OC(F)(F)F)CC4)cc3)c12 CHEMBL4104599 IC50 4.53 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)c12 CHEMBL4160854 IC50 4.71 nM
Cc1ccc(CO)cc1N(c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1)C(C)C CHEMBL1762548 IC50 5.0 nM
COc1cc(Nc2nccc(N(C)c3cc(CO)ccc3C)n2)cc(N2CCOCC2)c1 CHEMBL1762545 IC50 5.0 nM
Nc1ncnc2c1c(-c1cccc(O)c1)cn2[C@H]1C[C@@H](CN2CCC2)C1 CHEMBL3787112 IC50 5.0 nM
Cc1ccc(O)cc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL3321809 IC50 5.4 nM
COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl CHEMBL288441 IC50 5.5 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(CN3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762541 IC50 6.0 nM
COc1cccc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)n1 CHEMBL1762534 IC50 6.0 nM
CN(c1cccc(Cl)c1)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762524 IC50 6.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCN(O)CC3)c2)n1 CHEMBL1762540 IC50 7.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)n1 CHEMBL4165320 IC50 7.23 nM
Cc1cc(-c2c(Cl)cccc2Cl)cc2nnc(Nc3ccc(OCC[N+]4([O-])CCCC4)cc3)nc12 CHEMBL256101 Ki 7.27 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(C)c(Cl)c3)cc2)n1 CHEMBL4160813 IC50 7.68 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)nc(N3CCOCC3)c2)n1 CHEMBL1762550 IC50 8.0 nM
COCCOc1cc(Nc2nccc(N(C)c3cc(CO)ccc3C)n2)cc(N2CCOCC2)c1 CHEMBL1762544 IC50 8.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(OC3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762543 IC50 8.0 nM
Cc1cccc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762523 IC50 8.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762538 IC50 9.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(Br)cc(C(F)(F)F)c5)CC4)cc3)c12 CHEMBL4086694 IC50 9.22 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCCCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762537 IC50 10.0 nM
CN(c1cccc(CO)c1)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762528 IC50 10.0 nM
COc1ccc(C)c(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762527 IC50 10.0 nM
Cc1ccccc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762522 IC50 10.0 nM
c1cc(Nc2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c2cn[nH]c2c1 CHEMBL1271187 IC50 11.0 nM
CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(S(C)(=O)=O)c1 CHEMBL523088 IC50 12.0 nM
COCCN(c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1)c1cc(CO)ccc1C CHEMBL1762549 IC50 12.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 12.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Kd 12.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(OC(F)(F)F)ccc4Br)cc3)c12 CHEMBL4168788 IC50 12.1 nM
NC(=O)c1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(N2CCOCC2)c1 CHEMBL517720 IC50 13.0 nM
CN(c1ccnc(Nc2cccc(NS(C)(=O)=O)c2)n1)c1cccc2[nH]ncc12 CHEMBL1270182 IC50 13.0 nM
COc1ccnc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762533 IC50 13.0 nM
Nc1ncc(-c2ccccc2)c2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL241681 IC50 14.0 nM
CCCCn1c(-c2cc(-c3cccc4[nH]ncc34)ccc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL2333602 IC50 14.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL3321812 IC50 14.0 nM
CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(NS(C)(=O)=O)c1 CHEMBL496968 IC50 15.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)nc(N3CCOCC3)n2)n1 CHEMBL1762551 IC50 15.0 nM
NC(=O)c1c(N)n(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2F)c2nc3ccccc3nc12 CHEMBL3321813 IC50 15.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccccc3F)cc2)n1 CHEMBL4174374 IC50 15.34 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(F)c(F)c4)cc3)c12 CHEMBL4167759 IC50 15.46 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762536 IC50 16.0 nM
FC(F)(F)c1ccc(-c2cn(Cc3ccc(-c4cn[nH]c4)cc3)nn2)cc1 CHEMBL4575350 IC50 16.0 nM
CC(C)n1nc(-c2cc(O)cc(Br)c2)c2c(N)ncnc21 CHEMBL1242285 IC50 17.0 nM
Cc1ccc(CO)cc1N(C)c1ccnc(Nc2cc(C(=O)N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762542 IC50 17.0 nM
CN(c1ccccc1)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762521 IC50 17.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(Cl)c(Cl)c4)cc3)c12 CHEMBL4175943 IC50 17.48 nM
CS(=O)(=O)c1cccc(-c2cnc(N)c3c(-c4ccc(F)c(Cl)c4)csc23)c1 CHEMBL391691 IC50 18.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2C1CCCC1 CHEMBL1241676 IC50 18.0 nM
CO[C@@H](C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 CHEMBL402548 Kd apparent 18.0 nM
Nc1ncc(-c2cccc(S(N)(=O)=O)c2)c2scc(-c3ccc(F)c(Cl)c3)c12 CHEMBL241517 IC50 19.0 nM
Cc1ccc(C)c(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 CHEMBL1762526 IC50 19.0 nM
NC(=O)Cc1cccc(-c2cnc(N)c3c(-c4ccc(F)c(Cl)c4)csc23)c1 CHEMBL239182 IC50 20.0 nM
NC(=O)c1c(N)n(-c2cccc(NC(=O)c3cccc(C(F)(F)F)c3)c2)c2nc3ccccc3nc12 CHEMBL3321811 IC50 20.0 nM
NC(=O)c1c(N)n(-c2cccc(C(=O)Nc3cccc(C(F)(F)F)c3)c2)c2nc3ccccc3nc12 CHEMBL3321816 IC50 20.0 nM
CN(c1ccnc(Nc2cccc(CO)c2)n1)c1cccc2[nH]ncc12 CHEMBL1269964 IC50 21.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL3321817 IC50 21.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(Cl)cc4Cl)cc3)c12 CHEMBL4175949 IC50 21.35 nM
CS(=O)(=O)c1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(C(N)=O)c1 CHEMBL497195 IC50 23.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(C(C)C)c3)cc2)cn1 CHEMBL4175773 IC50 23.55 nM
NC(=O)c1c(N)n(-c2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2F)c2nc3ccccc3nc12 CHEMBL3321818 IC50 24.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)cc2)cn1 CHEMBL4167913 IC50 24.92 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL445162 IC50 25.0 nM
COc1ccc(Br)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1080639 IC50 26.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(OC(F)(F)F)ccc5Br)CC4)cc3)cc2n1 CHEMBL4162947 IC50 26.43 nM
Cc1cccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)c1 CHEMBL4553163 IC50 28.62 nM
COc1ccc(-c2ccc(Cn3cc(-c4cccc(Cl)c4)nn3)cc2)cn1 CHEMBL4452256 IC50 28.68 nM
Nc1ncc(-c2cccnc2)c2scc(-c3ccc(F)c(Cl)c3)c12 CHEMBL241516 IC50 29.0 nM
CN(C)C(=O)c1cccc(Nc2nccc(N(C)c3cccc4[nH]ncc34)n2)c1 CHEMBL1270075 IC50 29.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(C)c(Cl)c3)cc2)cn1 CHEMBL4168590 IC50 29.28 nM
Cc1cccc(C)c1/C=C/n1cnc2c(Nc3ccc(P(C)(C)=O)cc3)ncnc21 CHEMBL488840 IC50 30.0 nM
Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc12 CHEMBL249821 IC50 30.8 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4c3OCO4)n2)c1 CHEMBL1270569 IC50 34.0 nM
Cc1ccc(C(C)O)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 CHEMBL1762532 IC50 35.0 nM
CN(c1ccnc(Nc2cccc(S(C)(=O)=O)c2)n1)c1c(Cl)ccc2c1OCO2 CHEMBL1270976 IC50 36.0 nM
CN(c1ccnc(Nc2cccc(S(C)(=O)=O)c2)n1)c1cccc2[nH]ncc12 CHEMBL1271394 IC50 36.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(C(F)(F)F)ccc1O CHEMBL1079448 IC50 37.0 nM
COc1ccc(C(F)(F)F)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1079846 IC50 37.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@@H]2CN(C)C[C@@H]2C1 CHEMBL3544983 Kd apparent 37.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(F)c5)CC4)cc3)cc2n1 CHEMBL4166401 IC50 37.78 nM
Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(C(NC(C)(C)C)c3ccccn3)ns2)n1 CHEMBL4225923 IC50 38.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(C(F)(F)F)cc(C(F)(F)F)c5)CC4)cc3)c12 CHEMBL4075266 IC50 38.14 nM
O=C(Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1)Nc1ccc(F)c(F)c1 CHEMBL4174261 IC50 38.52 nM
NS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL257553 IC50 40.0 nM
Cc1cc(-c2c(Cl)cccc2Cl)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 CHEMBL230686 IC50 40.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccccc3Cl)cc2)n1 CHEMBL4172089 IC50 44.52 nM
COc1cc(-c2nn(C3CCCC3)c3ncnc(N)c23)ccc1N CHEMBL1241581 IC50 45.0 nM
COc1ccccc1-n1c(-c2ccccc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL574236 IC50 47.0 nM
O=C(Nc1cccc(Cl)c1)Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1 CHEMBL4163581 IC50 47.96 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(OC(F)(F)F)cc4Br)cc3)cc2n1 CHEMBL4060841 IC50 48.53 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(C(F)(F)F)ccc1F CHEMBL1079850 IC50 49.0 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCC4CCCC4)cc3)nnc2c1 CHEMBL3651296 IC50 49.0 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2c1 CHEMBL436137 IC50 49.0 nM
CCCCn1c(-c2ccccc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL2333603 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc([C@@H]2CCCN2)n1 CHEMBL3949400 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3910031 IC50 50.0 nM
CCO[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC CHEMBL3907230 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN(C)C)no1 CHEMBL3936440 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)no1 CHEMBL3939199 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCOCC2)no1 CHEMBL3944984 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(CN(C)C)n1 CHEMBL3971051 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(Cc2ccccc2)CCO1 CHEMBL3934158 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)OC(C)(C)C)CCO1 CHEMBL3924455 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(CN2CCOCC2)n1 CHEMBL3973688 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cscn1 CHEMBL3968322 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1CCCC1 CHEMBL3952048 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C2CCCCN2C(=O)OC(C)(C)C)n1 CHEMBL3904510 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C2CCN(C(=O)OC(C)(C)C)CC2)n1 CHEMBL3958507 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CCCCC1 CHEMBL3954731 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CCC1 CHEMBL3919501 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1OCCO1 CHEMBL3929188 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1OCCCO1 CHEMBL3949535 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1CCOCC1 CHEMBL3968843 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1CCCC1 CHEMBL3905012 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCN1CCCCC1 CHEMBL3907764 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)cs1 CHEMBL3913860 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc2c(s1)CNCC2 CHEMBL3945353 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCOCC2)cs1 CHEMBL3942671 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(COCc2ccccc2)no1 CHEMBL3984213 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCNCC2)n1 CHEMBL3945860 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCN(C)CC2)n1 CHEMBL3898088 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(N2CCNCC2)no1 CHEMBL3957171 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(N2CCN(C)CC2)no1 CHEMBL3959857 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCc2ccccc2)CCO1 CHEMBL3899485 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(C)C)CCO1 CHEMBL3952315 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C2CCCC2)CCO1 CHEMBL3965096 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C)CCN1C CHEMBL3983179 IC50 50.0 nM
CCN1CCN(c2nc(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)cs2)CC1 CHEMBL3895123 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc([C@@H]2CCCN2C)n1 CHEMBL3930429 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc([C@@H]2CCCN2C)no1 CHEMBL3933123 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C2CCCN2)n1 CHEMBL3909596 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(N2CCNCC2)n1 CHEMBL3944780 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(C)C)CCCO1 CHEMBL3947408 IC50 50.0 nM
CCN1CCC[C@H]1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 CHEMBL3910064 IC50 50.0 nM
CCN1CCCC(c2nc(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)cs2)C1 CHEMBL3897215 IC50 50.0 nM
CCN1CCCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 CHEMBL3952805 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCN(C)C2)n1 CHEMBL3930406 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCNC2)n1 CHEMBL3893575 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCCN2C)n1 CHEMBL3967776 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc([C@@H]2CSCN2)n1 CHEMBL3927549 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(CO)n1 CHEMBL3939717 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CCCN1C CHEMBL3914671 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CS(=O)(=O)c2ccccn2)no1 CHEMBL3903022 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(F)cc(F)c1 CHEMBL3900296 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3964556 IC50 50.0 nM
COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3955359 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC(F)F CHEMBL3921689 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3924380 IC50 50.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3955486 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1C[C@H]2OCC3(OCCO3)[C@H]2O1 CHEMBL3964605 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3895424 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3919145 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3Cl)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3958481 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3961005 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1O[C@@H]1C[C@H]2OC[C@H](OC)[C@H]2O1 CHEMBL3946590 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1C[C@@H]2CN(C)C[C@@H]2C1 CHEMBL3920036 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3931427 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3893416 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3914441 IC50 50.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3956820 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3959516 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3977450 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@H]1CN2CCCC[C@H]2CO1 CHEMBL3968192 IC50 50.0 nM
CCOC(=O)C(C)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3937598 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCOCCO)CCO1 CHEMBL3918670 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(Cc2ccc(F)cc2)CCO1 CHEMBL3910102 IC50 50.0 nM
COC(=O)CCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3979195 IC50 50.0 nM
C=CCCCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3981613 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(Cc2ccccn2)CCO1 CHEMBL3916759 IC50 50.0 nM
CCC#CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3919493 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(N2CCN(C)CC2)n1 CHEMBL3958678 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C2CCCN2C)n1 CHEMBL3956056 IC50 50.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3893032 IC50 50.0 nM
COc1cc(Nc2ncnc3cc(OCC4CN(C)CCO4)c(OC)cc23)c(OC)cc1Cl CHEMBL3944702 IC50 50.0 nM
COc1cc2c(Nc3cccc(Br)c3C)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3912287 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3966040 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)ccc3F)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3949155 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3951755 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)cc3Cl)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3904192 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)cc3Br)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3913993 IC50 50.0 nM
CCN1CCN(C)CC1COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3)c2cc1OC CHEMBL3968030 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(CN2CCCC2)n1 CHEMBL3900295 IC50 50.0 nM
CCC(CC)CN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3921228 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CC2CCCCC2)CCO1 CHEMBL3895890 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCO)CCO1 CHEMBL3893176 IC50 50.0 nM
CC#CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3933897 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C2CCC2)CCO1 CHEMBL3931193 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCC2CCCCC2)CCO1 CHEMBL3951403 IC50 50.0 nM
CC[C@@H](C)CN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3985896 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(C)C(C)=O)CCO1 CHEMBL3895645 IC50 50.0 nM
CCC(=O)CN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3965938 IC50 50.0 nM
CCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3929942 IC50 50.0 nM
CCCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3932698 IC50 50.0 nM
CCCCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3976896 IC50 50.0 nM
CCCCCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3979317 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCc2ccccc2)CCO1 CHEMBL3916297 IC50 50.0 nM
C=CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3946469 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1OCCN(CC(=O)c2ccccc2)C1=O CHEMBL3965160 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCF)CCO1 CHEMBL3955447 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CC=C(C)C)CCO1 CHEMBL3932218 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C/C=C/Br)CCO1 CHEMBL3898138 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCC(C)C)CCCO1 CHEMBL3947769 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CC2CCCCC2)CCCO1 CHEMBL3912646 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCC2CCCCC2)CCCO1 CHEMBL3914394 IC50 50.0 nM
CCC(CC)CN1CCCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3928439 IC50 50.0 nM
COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3953937 IC50 50.0 nM
CCN1CCN(CC)C(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3937092 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(/C(N)=N/C#N)CC1 CHEMBL3939874 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(S(=O)(=O)Cc2ccccc2)CCO1 CHEMBL3901787 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(S(=O)(=O)c2ccc(F)cc2)CCO1 CHEMBL3958778 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(S(=O)(=O)c2ccccc2)CCO1 CHEMBL3933398 IC50 50.0 nM
CCCCS(=O)(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3893845 IC50 50.0 nM
COc1cccc(CC(=O)N2CCOC(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)C2)c1 CHEMBL3945062 IC50 50.0 nM
CCCC(C)C(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3986123 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)Cc2ccc(Cl)cc2)CCO1 CHEMBL3941200 IC50 50.0 nM
CCCC(CCC)C(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3959038 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)CCC(C)C)CCO1 CHEMBL3942387 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)c2cc(F)ccc2F)CCO1 CHEMBL3982666 IC50 50.0 nM
CCC(C(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1)c1ccccc1 CHEMBL3894418 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)c2c(F)ccc(F)c2F)CCO1 CHEMBL3929966 IC50 50.0 nM
CCCCCC(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3931724 IC50 50.0 nM
CCCCC(CC)C(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3953606 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)CCc2ccccc2)CCO1 CHEMBL3918306 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)C(C)(C)C)CCO1 CHEMBL3907879 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)c2cccc3ccccc23)CCO1 CHEMBL3905114 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)c2ccc3c(c2)OCO3)CCO1 CHEMBL3962355 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)cc3C)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3892117 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(C)c3)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3907215 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)cc3Cl)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3911207 IC50 50.0 nM
CN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2O)C1 CHEMBL3955824 IC50 50.0 nM
COC(=O)CCC(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 CHEMBL3899440 IC50 50.0 nM
CCC1(C)CN(C)CC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)O1 CHEMBL3931393 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(C)c3)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3934095 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CNCC(C)(C)O1 CHEMBL3914189 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C)CC(C)(C)O1 CHEMBL3928601 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CNC(C)(C)CO1 CHEMBL3962203 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CN(C)C(C)(C)CO1 CHEMBL3959495 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CN(C)CC(C)(C)O1 CHEMBL3939133 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(F)c3F)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3941947 IC50 50.0 nM
COc1cc2c(Nc3cc(F)c(Br)cc3F)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3952465 IC50 50.0 nM
COc1cc2c(Nc3cc(F)c(Br)c(F)c3)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3955083 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3C)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3924098 IC50 50.0 nM
COc1cc2c(Nc3ccc(C)c(Cl)c3Cl)ncnc2cc1OCC1CN(C)CCO1 CHEMBL3891059 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN(C)CC(=O)N1 CHEMBL3935851 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN(C)CC(=O)N1 CHEMBL3933130 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN(C)CC(=O)N1C CHEMBL3891130 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN(C)CC(=O)N1C CHEMBL3909603 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1=CO[C@H]2[C@H]1OC[C@@]21COC(C)(C)O1 CHEMBL3965625 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2O CHEMBL3945028 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2SC CHEMBL3947643 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2N1CCOCC1 CHEMBL3921861 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2N1CCN(C)CC1 CHEMBL3972940 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2N1CCCC1 CHEMBL3923645 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC(C)=O CHEMBL3933359 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2O CHEMBL3893363 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2S(C)(=O)=O CHEMBL3896067 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2N CHEMBL3976788 IC50 50.0 nM
CN[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC CHEMBL3974328 IC50 50.0 nM
CCN(CC)[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC CHEMBL3909572 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2N1CCCCC1 CHEMBL3927849 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2NC(C)=O CHEMBL3961417 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2NS(C)(=O)=O CHEMBL3943734 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1CCN(C)C1 CHEMBL3971560 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CCOC1 CHEMBL3939828 IC50 50.0 nM
COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2F CHEMBL3937048 IC50 50.0 nM
COc1cc2c(N[C@H]3COC[C@@H]3OC)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2O CHEMBL3916828 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2C(F)(F)F CHEMBL3938869 IC50 50.0 nM
CC1CCC(n2nc(-c3ccc(F)c(O)c3)c3c(N)ncnc32)C1 CHEMBL1242656 IC50 54.0 nM
Clc1n[nH]c2cccc(Nc3ccnc(Nc4cc(N5CCOCC5)cc(N5CCOCC5)c4)n3)c12 CHEMBL1270279 IC50 55.0 nM
Cc1cc(-c2ccccc2Cl)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 CHEMBL268825 IC50 58.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1 CHEMBL1236772 IC50 61.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 CHEMBL1081198 IC50 62.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCCC1 CHEMBL1242568 IC50 64.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(C(F)(F)F)ccc1Cl CHEMBL1080190 IC50 66.0 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(C(=O)N4CCN(C)CC4)cc3)nnc2c1 CHEMBL3648039 IC50 66.0 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3nc(C(=O)NCCN4CCCC4)cs3)nnc2c1 CHEMBL3648061 IC50 66.1 nM
Cc1n[nH]c2cccc(Nc3ccnc(Nc4cc(N5CCOCC5)cc(N5CCOCC5)c4)n3)c12 CHEMBL1270183 IC50 67.0 nM
CCCCn1c(-c2ccc(F)cc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL2333595 IC50 68.0 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(C(=O)NCCN4CCCC4)o3)nnc2c1 CHEMBL3648058 IC50 68.7 nM
CN(Cc1ccncc1)c1nc(-c2cccc(NC(=O)Nc3cccc(C(F)(F)F)c3)c2)cn2ccnc12 CHEMBL1079810 IC50 69.0 nM
Fc1ccccc1-c1cn(Cc2ccc(-c3cn[nH]c3)cc2)nn1 CHEMBL4437530 IC50 73.15 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)cc2)n1 CHEMBL4164213 IC50 73.43 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nnc2c1 CHEMBL231218 IC50 73.7 nM
NC(=O)c1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(C(N)=O)c1 CHEMBL460600 IC50 77.0 nM
COc1ccc(Cl)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1081403 IC50 77.0 nM
COc1ccc(C)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1080640 IC50 78.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(Br)cc(C(F)(F)F)c5)CC4)cc3)cc2n1 CHEMBL4165234 IC50 78.92 nM
CS(=O)(=O)Nc1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1 CHEMBL1270076 IC50 84.0 nM
Cc1ccc(C(=O)Nc2ccc(CN3Cc4cn[nH]c4C3)c(Cl)c2)cc1C#Cc1cnc2cccnn12 CHEMBL4638981 IC50 84.6 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)n1 CHEMBL4171035 IC50 86.65 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(Cl)cc3Cl)cc2)n1 CHEMBL4160431 IC50 87.24 nM
c1cc(Nc2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c2[nH]ncc2c1 CHEMBL1271287 IC50 89.0 nM
NC(=O)c1c(N)n(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)c2nc3ccccc3nc12 CHEMBL3321822 IC50 89.0 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)cc2n1 CHEMBL4066813 IC50 92.59 nM
O=C(Nc1ccc(-c2ccc3c(=O)nc[nH]c3c2)cc1)C1(C(=O)Nc2cccc(C(F)(F)F)c2)CCC1 CHEMBL4164127 IC50 93.36 nM
CC(C)n1nc(-c2ccc3cc(O)ccc3c2)c2c(N)ncnc21 CHEMBL1242662 IC50 95.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(N(CC#N)c3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL1271081 IC50 95.0 nM
Nc1ncnc2c1c(-c1cc(O)cc(F)c1)nn2C1CCCC1 CHEMBL1242199 IC50 96.0 nM
Fc1ccccc1-c1cn(Cc2ccc(-c3cccnc3)cc2)nn1 CHEMBL4454065 IC50 96.86 nM
CCN(Cc1cc(Nc2nc(C)cn3c(-c4cn[nH]c4)cnc23)sn1)C(C)(C)CO CHEMBL1650533 IC50 100.0 nM
CNc1ncc2cc(-c3cc(NC(=O)NCCC(C)(C)C)c(F)cc3C)c(C)nc2n1 CHEMBL3577124 IC50 100.0 nM
CCN(CCO)Cc1cc(Nc2nc(C)cn3c(-c4cn[nH]c4)cnc23)sn1 CHEMBL4228240 IC50 100.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(Cl)ccc1Cl CHEMBL1080353 IC50 101.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(OCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 CHEMBL1079809 IC50 105.0 nM
Nc1ncnc2c1c(-c1ccc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1242295 IC50 105.0 nM
CC(C)n1nc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21 CHEMBL1241484 IC50 106.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3cccc(C(C)C)c3)cc2)n1 CHEMBL4167663 IC50 106.84 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3cccc(F)c3)cc2)n1 CHEMBL4166465 IC50 106.84 nM
CN1CCN(C2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)C5(C(=O)Nc6ccc(F)cc6)CC5)c(F)c4)ccn3)CC2)CC1 CHEMBL3039525 Kd apparent 109.0 nM
COc1cc(-c2cnc(N)c3c(-c4ccc(F)c(Cl)c4)csc23)cc(OC)c1OC CHEMBL248304 IC50 110.0 nM
CS(=O)(=O)c1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(S(C)(=O)=O)c1 CHEMBL497194 IC50 114.0 nM
c1cc(Nc2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c2nn[nH]c2c1 CHEMBL1271393 IC50 115.0 nM
c1cc(Nc2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c2cc[nH]c2c1 CHEMBL1271288 IC50 117.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(N(CCO)c3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL1271186 IC50 121.0 nM
COc1ccc(C#N)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1079750 IC50 125.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 126.4 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccnc(OCCN4CCCC4)c3)nnc2c1 CHEMBL437004 IC50 128.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3c(C)cccc3C)cc2)cn1 CHEMBL4165168 IC50 133.73 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(Cl)ccc1Oc1ccccc1 CHEMBL1076138 IC50 138.0 nM
Cc1ccc(C(=O)Nc2ccc(CN3CCC4C=NNC4C3)c(Cl)c2)cc1C#Cc1cnc2cccnn12 CHEMBL4640297 IC50 138.1 nM
CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1N[C@H]1CC[C@H](CN(C)C)CC1 CHEMBL3688339 Kd apparent 143.0 nM
CC(=O)Nc1cn2cc(-c3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3C)ccc2n1 CHEMBL4216073 IC50 150.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 CHEMBL1081061 IC50 158.0 nM
Cc1ccc(Cl)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1081573 IC50 160.0 nM
Cc1ccc(O)cc1-n1c(=O)c2c(c3c(N)ncnc31)CCCC2 CHEMBL2152704 IC50 160.0 nM
Cc1ccc(CO)cc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL3321804 IC50 160.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Cl)cc5Cl)CC4)cc3)cc2n1 CHEMBL4170879 IC50 160.1 nM
O=C(Nc1cccc(Cl)c1)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1080024 IC50 165.0 nM
CC(C)n1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242377 IC50 166.0 nM
COc1ccc(-c2nn(C3CCC(C)C3)c3ncnc(N)c23)cc1O CHEMBL1242202 IC50 166.0 nM
Nc1ncnc2c1c(-c1ccc3cc[nH]c3c1)nn2C1CCCC1 CHEMBL1242664 IC50 170.0 nM
Cc1cn(-c2cc(C(=O)Nc3ccc(C)c(-n4c(N)c(C(N)=O)c5nc6ccccc6nc54)c3)cc(C(F)(F)F)c2)cn1 CHEMBL3321814 IC50 170.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Cl)c(Cl)c5)CC4)cc3)c12 CHEMBL4083001 IC50 170.11 nM
CCCCCn1c(-c2ccccc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL2333593 IC50 177.0 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(Cl)c(Cl)c4)cc3)cc2n1 CHEMBL4085653 IC50 179.6 nM
CCCCn1c(-c2ccccc2Cl)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL2333597 IC50 182.0 nM
COc1cc(-c2cnc(N)c3c(-c4ccc(Cl)cc4)csc23)cc(OC)c1OC CHEMBL248100 IC50 190.0 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1081312 IC50 190.0 nM
OCc1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1 CHEMBL1269859 IC50 204.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ccoc34)n2)c1 CHEMBL1270671 IC50 205.0 nM
COc1cc(OC)c(NC(=O)Nc2cccc(-c3cn4ccnc4c(NCc4ccncc4)n3)c2)cc1Br CHEMBL1080207 IC50 206.0 nM
CCOc1cc(OCC)c(C(F)(F)F)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1075667 IC50 211.0 nM
COc1ccccc1-n1c(-c2cccc(O)c2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL575335 IC50 213.0 nM
O=C(Nc1cccc(Br)c1)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1080359 IC50 213.0 nM
O=C(Nc1ccc(-c2ccc3c(=O)nc[nH]c3c2)cc1)C1(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC1 CHEMBL4174775 IC50 216.58 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ncoc34)n2)c1 CHEMBL1270773 IC50 219.0 nM
NC(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL500724 IC50 220.0 nM
CC(C)n1nc(-c2ccc(Br)c(O)c2)c2c(N)ncnc21 CHEMBL1241578 IC50 220.0 nM
COc1cc(-c2cnc(N)c3c(-c4cccc(Cl)c4Cl)csc23)cc(OC)c1OC CHEMBL245636 IC50 230.0 nM
CC(C)n1nc(-c2ccc3[nH]ccc3c2)c2c(N)ncnc21 CHEMBL1242294 IC50 230.0 nM
Cc1ccccc1-n1c(N)c(C(N)=O)c2nc3ccccc3nc21 CHEMBL3321800 IC50 230.0 nM
COc1ccccc1-n1c(-c2ccc(O)cc2C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL583871 IC50 236.0 nM
COc1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(OC)c1OC CHEMBL256725 IC50 240.0 nM
CC(C)n1nc(-c2ccc3ncccc3c2)c2c(N)ncnc21 CHEMBL1233882 IC50 240.0 nM
COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1F CHEMBL1241483 IC50 244.0 nM
COCCN(c1ccnc(Nc2cccc(S(C)(=O)=O)c2)n1)c1c(Cl)ccc2c1OCO2 CHEMBL1271082 IC50 246.0 nM
CN(C)C(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1 CHEMBL1269965 IC50 246.0 nM
Cc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1O CHEMBL1242026 IC50 249.0 nM
CC(C)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21 CHEMBL1242198 IC50 251.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCCCCC1 CHEMBL1242750 IC50 254.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2[C@H]1CCOC1 CHEMBL1241678 IC50 256.0 nM
COc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1O CHEMBL1242201 IC50 258.0 nM
COc1ccc(-c2ccc(Cn3cc(-c4ccccc4F)nn3)cc2)cn1 CHEMBL4440813 IC50 266.77 nM
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(-n4c(N)c(C(N)=O)c5nc6ccccc6nc54)c3)cc(C(F)(F)F)c2)cn1 CHEMBL3321819 IC50 270.0 nM
CN(C)[C@H]1CCCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1 CHEMBL386637 IC50 290.0 nM
CC(C)n1nc(-c2ccc3cc[nH]c3c2)c2c(N)ncnc21 CHEMBL1242574 IC50 290.0 nM
CC(C)c1cc(CNc2nc(Nc3cc(C4CC4)[nH]n3)cc(N3CCN(C)CC3)n2)on1 CHEMBL3545085 Kd apparent 292.0 nM
NS(=O)(=O)c1ccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc1 CHEMBL256348 IC50 300.0 nM
Cc1cccc(NC(=O)Nc2cccc(-c3cn4ccnc4c(NCc4ccncc4)n3)c2)c1 CHEMBL1080360 IC50 300.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4ccoc34)n2)c1 CHEMBL1270670 IC50 300.0 nM
COc1ccccc1-n1c(-c2ccccc2Cl)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL2333600 IC50 300.0 nM
COc1cccc(-n2c(N)c(C(N)=O)c3nc4ccccc4nc32)c1 CHEMBL3774835 IC50 300.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC CHEMBL1289494 Kd apparent 310.0 nM
CC(C)n1nc(-c2cccc(O)c2)c2c(N)ncnc21 CHEMBL1230790 IC50 316.0 nM
Cc1cc(O)ccc1-c1nn(C(C)C)c2ncnc(N)c12 CHEMBL1242024 IC50 316.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)n1 CHEMBL4159244 IC50 321.05 nM
Nc1ncnc2c1c(-c1ccc(Br)c(O)c1)nn2C1CCC1 CHEMBL1242287 IC50 322.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3c(C)cccc3C)cc2)n1 CHEMBL4170942 IC50 334.72 nM
CC(C)n1nc(-c2cnc3[nH]ccc3c2)c2c(N)ncnc21 CHEMBL1242293 IC50 340.0 nM
C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(Cl)c(Cl)c4F)ncnc3cc2OC)CC1 CHEMBL3545154 Kd apparent 340.0 nM
Nc1ncnc2c1c(-c1ccc(Br)c(O)c1)nn2C1CCCC1 CHEMBL1242376 IC50 347.0 nM
COc1cc2c(Nc3c(Cl)ccc4c3OCO4)ncnc2cc1OCCCN1CCCCC1 CHEMBL169186 IC50 350.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2CC1CCNC1 CHEMBL1241770 IC50 352.0 nM
CC(C)n1nc(-c2ccc3c(ccn3C(=O)OC(C)(C)C)c2)c2c(N)ncnc21 CHEMBL1242852 IC50 353.0 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(-n3c(N)c(C(N)=O)c4nc5ccccc5nc43)cc2)cc1 CHEMBL4792853 EC50 360.0 nM
CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc(C(N)=O)c1 CHEMBL498404 IC50 370.0 nM
Nc1ncnc2c1c(-c1ccc3occc3c1)nn2C1CCCC1 CHEMBL1241491 IC50 380.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Cl)cc5Cl)CC4)cc3)c12 CHEMBL4072514 IC50 383.59 nM
Nc1ncc(-c2cccc(Cl)c2)c2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL391692 IC50 389.0 nM
Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(Cc3ccccn3)ns2)n1 CHEMBL4227082 IC50 390.0 nM
Cc1cc(-c2ccccc2)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 CHEMBL230685 IC50 391.0 nM
COc1cc(OC)c(NC(=O)Nc2cccc(-c3cn4ccnc4c(NCc4ccncc4)n3)c2)cc1Cl CHEMBL1081013 IC50 402.0 nM
CCN(CC)CCOc1ccc(Nc2cc(NC(=O)Nc3c(Cl)cccc3Cl)ncn2)cc1 CHEMBL253292 IC50 430.0 nM
CN(c1ccnc(Nc2nc(N3CCOCC3)cc(N3CCOCC3)n2)n1)c1cccc2[nH]ncc12 CHEMBL1270379 IC50 432.0 nM
CCOc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1OC CHEMBL1240554 IC50 456.0 nM
Cc1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL404444 IC50 460.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2[C@@H]1CCNC1 CHEMBL1241677 IC50 468.0 nM
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC CHEMBL301018 IC50 480.0 nM
O=C(Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1)Nc1ccc(Cl)c(C(F)(F)F)c1 CHEMBL4163655 IC50 491.93 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@H]1CCNC1 CHEMBL1242657 IC50 492.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(Cl)c(Cl)cc1Cl CHEMBL1079794 IC50 517.0 nM
COc1cc(OC)c(C(F)(F)F)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1075666 IC50 518.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2[C@@H]1CCOC1 CHEMBL1241768 IC50 519.0 nM
COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1 CHEMBL24828 Kd 520.0 nM
CCCCn1c(-c2ccccc2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL271967 IC50 538.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ocnc34)n2)c1 CHEMBL1270874 IC50 549.0 nM
N#Cc1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL254588 IC50 550.0 nM
CNC(=O)CN1CCC(Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CC1 CHEMBL2408045 Kd apparent 556.0 nM
CCCCn1c(-c2ccc(O)cc2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL575325 IC50 558.0 nM
O=C(O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2F)=NC3)cc1 CHEMBL259084 Kd 560.0 nM
NC(=O)c1c(N)n(-c2ccc(NC(=S)Nc3cccc(C(F)(F)F)c3)cc2)c2nc3ccccc3nc12 CHEMBL3321823 IC50 560.0 nM
CC(C)n1nc(-c2cccc(O)c2F)c2c(N)ncnc21 CHEMBL1242110 IC50 566.0 nM
C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL601719 Kd 570.0 nM
Nc1ncc(Br)c2scc(-c3ccc(F)c(Cl)c3)c12 CHEMBL239180 IC50 575.0 nM
Clc1ccc2c(c1Nc1ccnc(Nc3cccc(N4CCOCC4)c3)n1)OCO2 CHEMBL255874 IC50 580.0 nM
Oc1ccc(Nc2nnc3cc(-c4c(Cl)cccc4Cl)ccc3n2)cc1 CHEMBL3651299 IC50 596.0 nM
Cc1cc(-c2c(Cl)cccc2Cl)cc2nnc(Nc3ccc(O)cc3)nc12 CHEMBL3651269 IC50 596.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 600.0 nM
CNc1ncc2cc(-c3cc(F)ccc3F)c(=O)n(CCCCN)c2n1 CHEMBL5425418 IC50 607.0 nM
O=C(NC(=S)Nc1ccc(O)c(-c2nc3ccccc3s2)c1)c1ccc([N+](=O)[O-])cc1 CHEMBL460746 IC50 610.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@@H]1CCOC1 CHEMBL1242749 IC50 611.0 nM
Nc1n[nH]c2cccc(-c3cccc(NC(=O)C4(C(=O)Nc5cc(Br)cc(C(F)(F)F)c5)CC4)c3)c12 CHEMBL4085495 IC50 613.0 nM
CC(C)n1nc(-c2ccc(O)c(F)c2)c2c(N)ncnc21 CHEMBL1241945 IC50 628.0 nM
COc1cccc(-c2nn(C(C)C)c3ncnc(N)c23)c1 CHEMBL1242029 IC50 628.0 nM
CS(=O)(=O)c1ccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc1 CHEMBL258016 IC50 630.0 nM
COc1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL402903 IC50 640.0 nM
CCS(=O)(=O)c1cccc(-c2cc(C(=O)NC3CCN(C)CC3)c(C)c3[nH]c4ncc(C)cc4c23)c1 CHEMBL3544932 Kd apparent 656.0 nM
Nc1ncnc2c1c(-c1cnc3ccccc3c1)nn2C1CCCC1 CHEMBL1242755 IC50 660.0 nM
Nc1ncc(NC(=O)c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2Cl)cc1Cl CHEMBL475817 IC50 672.0 nM
CC(C)n1nc(-c2ccc3occc3c2)c2c(N)ncnc21 CHEMBL1241490 IC50 675.0 nM
CC1(C)CC[C@@H](COc2cccc(-c3cn([C@H]4C[C@@H](CN5CCC5)C4)c4ncnc(N)c34)c2)O1 CHEMBL3786567 IC50 690.0 nM
CCCCn1c(-c2cccc(O)c2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 CHEMBL566959 IC50 691.0 nM
[2H]C([2H])(c1cc(Nc2nc(C)cn3c(-c4cn[nH]c4)cnc23)sn1)N1CCC(F)(F)C1 CHEMBL1650551 IC50 700.0 nM
Cc1cc(-c2cc(OC(=O)c3ccccc3)ccc2Cl)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 CHEMBL403989 Kd apparent 711.0 nM
COc1ccc(C)c(-n2c(N)c(C(N)=O)c3nc4ccccc4nc32)c1 CHEMBL3321803 IC50 720.0 nM
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1 CHEMBL255863 Kd 730.0 nM
COc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1O CHEMBL1242114 IC50 737.0 nM
CS(=O)(=O)Nc1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 CHEMBL496574 IC50 741.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)c1cccc(C(F)(F)F)c1 CHEMBL1079795 IC50 744.0 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 750.0 nM
COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)cc(OC)c1OC CHEMBL1242660 IC50 760.0 nM
Nc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1O CHEMBL1241487 IC50 764.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2ccccc2)c2nc4cc(OC)ccc4[nH]2)C(=O)N3)CC1 CHEMBL2086751 IC50 765.0 nM
Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCC(F)(F)C3)ns2)n1 CHEMBL1650545 IC50 770.0 nM
COc1cc2nc(Nc3cc(C)[nH]n3)nc(Nc3cccc(-c4nc5ccccc5s4)c3)c2cc1OC CHEMBL522785 IC50 780.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(OC(F)(F)F)ccc5Br)CC4)cc3)c12 CHEMBL4093247 IC50 787.89 nM
Clc1ccc2c(Nc3ccc(-c4nc5ccccc5s4)c(Cl)c3)ncnc2c1 CHEMBL514016 IC50 800.0 nM
Cc1ccc(NC(=O)Nc2cccc(-c3cn4ccnc4c(NCc4ccncc4)n3)c2)cc1C(F)(F)F CHEMBL1079751 IC50 810.0 nM
c1cc(Nc2ncnc3[nH]cnc23)cc(-c2nc3ccccc3s2)c1 CHEMBL443906 IC50 840.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1ccc(F)c(C(F)(F)F)c1 CHEMBL1081740 IC50 850.0 nM
CC(C)(C)OC(=O)n1ccc2cc(-c3nn(C4CCCC4)c4ncnc(N)c34)ccc21 CHEMBL1242853 IC50 871.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@H]1CCOC1 CHEMBL1242748 IC50 882.0 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1 CHEMBL103667 IC50 900.0 nM
CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4c(Cl)c[nH]c34)n2)c1 CHEMBL1270975 IC50 913.0 nM
Cc1ccc(C)c(NC(=O)Nc2cccc(-c3cn4ccnc4c(NCc4ccncc4)n3)c2)c1 CHEMBL1080191 IC50 938.0 nM
O=c1ncn2nc(Sc3ccc(F)cc3F)ccc2c1-c1c(Cl)cccc1Cl CHEMBL119385 Kd 1000.0 nM
Clc1ccc2c(c1Nc1ccnc(Nc3ccc(N4CCOCC4)cc3)n1)OCO2 CHEMBL255875 IC50 1000.0 nM
Fc1cc(-c2nc3ccccc3s2)ccc1Nc1ncnc2cc(Cl)ccc12 CHEMBL473557 IC50 1000.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1c(Cl)cccc1Cl CHEMBL1081402 IC50 1000.0 nM
C[C@H](CN)n1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242378 IC50 1000.0 nM
C[C@H](CN)n1nc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21 CHEMBL1241579 IC50 1000.0 nM
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 CHEMBL939 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(COC(=O)c2ccccc2)n1 CHEMBL3900567 IC50 1000.0 nM
COc1cc2c(Nc3cccc(Br)c3C)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3895458 IC50 1000.0 nM
COc1cc2c(Nc3cccc(Cl)c3C)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC CHEMBL3959160 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@@H]2CCO[C@H]12 CHEMBL3932115 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@H]2OC CHEMBL3929354 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC(=O)N1CCOCC1 CHEMBL3914264 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(-c2ccc(N3CCCC3)cc2)cs1 CHEMBL3955873 IC50 1000.0 nM
CCN(CC)c1ccc(-c2csc(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)n2)cc1 CHEMBL3922630 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(-c2ccc(O)c(C(N)=O)c2)cs1 CHEMBL3943632 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CCCCC1 CHEMBL3979687 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(-c2cccnc2)cs1 CHEMBL3896044 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(-c2ccccn2)cs1 CHEMBL3976826 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(-c2ccncc2)cs1 CHEMBL3916485 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)no1 CHEMBL3900858 IC50 1000.0 nM
COc1ccc(-c2nc(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)no2)cc1 CHEMBL3985840 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(-c2ccc(C(F)(F)F)cc2)n1 CHEMBL3983201 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(-c2ccc(Cl)cc2)n1 CHEMBL3963620 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(-c2c(C)noc2C)n1 CHEMBL3937857 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc2ccc(Cl)cc12 CHEMBL3929002 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(-c2ccc(C(C)(C)C)cc2)no1 CHEMBL3951099 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(N(C)C)n1 CHEMBL3971864 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(C(F)(F)F)cc(Cl)c2c1 CHEMBL3948661 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(-c2ccccc2)n1 CHEMBL3946018 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(Br)cc(Br)c1 CHEMBL3961982 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(F)cc2c1OCOC2 CHEMBL3952493 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(-c2c(Cl)cccc2Cl)noc1C CHEMBL3893128 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nccn1Cc1ccccc1 CHEMBL3895848 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nnc(-c2ccc(C)cc2)o1 CHEMBL3944502 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(-c2ccccc2OC)n1 CHEMBL3933848 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(S(=O)(=O)c2ccc(C)cc2)CCO1 CHEMBL3970332 IC50 1000.0 nM
CCCCc1ccc(C(=O)N2CCOC(COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5)c4cc3OC)C2)cc1 CHEMBL3983450 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CN(C(=O)OC(C)(C)C)C(C)(C)CO1 CHEMBL3916953 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2OS(C)(=O)=O CHEMBL3986082 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2NC(F)(F)F CHEMBL3958721 IC50 1000.0 nM
COc1cc2c(Nc3ccc(N4CCN(C)CC4)cc3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2F CHEMBL3924442 IC50 1000.0 nM
COc1cc2c(Nc3ccc(N4CCN(C)C(F)C4)cc3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2F CHEMBL3890300 IC50 1000.0 nM
COc1cc2c(Nc3ccc(N4CCN(C)CC4)c(Cl)c3Cl)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2F CHEMBL3893058 IC50 1000.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3N3CCN(C)CC3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2F CHEMBL3985116 IC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM