C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCCCCC[S+]([O-])CCCC(F)(F)C(F)(F)F)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL1358 IC50 2.0 nM
Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Cl CHEMBL402491 IC50 3.3 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O CHEMBL135 IC50 3.6 nM
Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Br CHEMBL250097 IC50 3.6 nM
Oc1ccc(-c2cc(Br)c3cc(O)ccc3n2)cc1 CHEMBL198411 IC50 4.3 nM
COc1cc(/C=C(\C#N)C(N)=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4533857 IC50 4.33 nM
COCCNC(=O)/C(C#N)=C/c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(OC)c1 CHEMBL4578651 IC50 4.33 nM
Oc1ccc(-c2cc(Cl)c3cc(O)ccc3n2)cc1 CHEMBL372783 IC50 4.6 nM
COc1cc(/C=C(\C#N)C(=O)NCCOCCC(=O)O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4440692 IC50 4.67 nM
CN1CCC[C@H]1CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4170306 IC50 5.0 nM
COc1cc(/C=C(\C#N)C(=O)NCCOCCOCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4543370 IC50 5.33 nM
COc1cc(/C=C(\C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4467767 IC50 5.33 nM
COc1cc(/C=C(\C#N)C(=O)O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4514580 IC50 5.67 nM
COc1cc(/C=C(\C#N)C(=O)NCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4445475 IC50 5.67 nM
COc1cc(/C=C(\C#N)C(=O)NCCCCC(=O)O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4444248 IC50 6.0 nM
N#Cc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 CHEMBL402492 IC50 6.1 nM
COc1cc(/C=C(\C#N)C(=O)NCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4456486 IC50 6.33 nM
COc1cc(/C=C(\C#N)C(=O)NCCOCCOCCOCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4521251 IC50 7.0 nM
COc1cc(/C=C(\C#N)C(=O)NCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4461157 IC50 7.33 nM
COc1cc(/C=C(\C#N)C(=O)NCCCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4532018 IC50 7.67 nM
COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)N(CCN5CCOCC5)C4=O)ccc32)c(C(F)(F)F)c1 CHEMBL4169272 IC50 8.0 nM
COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)N(C5CCC(C(=O)O)CC5)C4=O)ccc32)c(C(F)(F)F)c1 CHEMBL4161346 IC50 8.0 nM
CC(=O)NS(=O)(=O)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4166492 IC50 8.0 nM
COc1cc(/C=C2\SC(=O)N(CCOCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(-c4scnc4C)cc3)C(C)(C)C)C2=O)ccc1Oc1ccc(C#N)cc1C(F)(F)F CHEMBL4218019 IC50 8.0 nM
O=C(O)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4159613 IC50 9.0 nM
COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)N(CC(=O)O)C4=O)ccc32)c(C(F)(F)F)c1 CHEMBL4163909 IC50 9.0 nM
COc1cc(/C=C(\C#N)C(=O)NCCOCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4538025 IC50 9.33 nM
O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 CHEMBL44 IC50 10.0 nM
COc1cc(/C=C(\C#N)C(=O)NCCOCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4461263 IC50 11.33 nM
O=C(O)C1CCC(N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)CC1 CHEMBL4166832 IC50 12.0 nM
COc1cc(/C=C(\C#N)C(=O)NCCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4469374 IC50 12.33 nM
COc1cc(/C=C(\C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4570799 IC50 12.67 nM
COC(=O)c1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2OC)c2ccccc12 CHEMBL1671982 IC50 13.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1Cc1nnn[nH]1 CHEMBL4165363 IC50 13.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C1CCN(CCO)CC1 CHEMBL4172209 IC50 15.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C[C@H]1COCCN1 CHEMBL4172522 IC50 15.0 nM
COC(=O)c1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2OC)c(C(F)(F)F)c1 CHEMBL1671969 IC50 16.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C1CCNCC1 CHEMBL4163054 IC50 16.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1CCN1CCCC1 CHEMBL4163375 IC50 17.0 nM
CS(=O)(=O)NC(=O)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4173278 IC50 18.0 nM
NS(=O)(=O)NC(=O)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4177113 IC50 19.0 nM
CN1CCC(N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)CC1 CHEMBL4173757 IC50 19.0 nM
COC(=O)/C(C#N)=C/c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(OC)c1 CHEMBL4443118 IC50 20.33 nM
CC(C)c1cccc(-n2cc(C(=O)c3ccccc3N)nn2)c1 CHEMBL2381353 IC50 21.0 nM
C=Cc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 CHEMBL250300 IC50 22.0 nM
COCCOc1cccc(Cn2nc(C)c3cc(C(=O)N4CCN(c5ccc(C(C)=O)cn5)[C@H](C)C4)sc32)c1 CHEMBL4093786 IC50 22.0 nM
CN1CC[C@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@@H](F)C1 CHEMBL4164196 IC50 22.0 nM
CN(C)S(=O)(=O)NC(=O)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4169919 IC50 23.0 nM
N[C@@H](CO)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4164640 IC50 23.0 nM
CN1CC[C@@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@H](O)C1 CHEMBL4175927 IC50 23.0 nM
CN1CC[C@@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@H](F)C1 CHEMBL4174856 IC50 23.0 nM
C[C@H](N)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O CHEMBL4161594 IC50 24.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCc4cn(CC5COc6ccccc6O5)nn4)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL2326068 IC50 24.4 nM
O=C(CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O)NS(=O)(=O)N1CCCC1 CHEMBL4161992 IC50 25.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCNC[C@H]1O CHEMBL4168072 IC50 25.0 nM
O=C(O)CN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(C(F)(F)F)cc3C(F)(F)F)c2)C1=O CHEMBL4171282 IC50 26.0 nM
N#Cc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 CHEMBL197667 IC50 28.0 nM
Cc1nn(Cc2ccc(Cl)cc2C(F)(F)F)c2ccc(/C=C3\SC(=O)N(CC(=O)O)C3=O)cc12 CHEMBL4167938 IC50 28.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc(-n5cccc5)cc4)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL2326072 IC50 28.3 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)cc1C(F)(F)F CHEMBL1671971 IC50 33.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCNC[C@H]1F CHEMBL4171419 IC50 34.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL1671970 IC50 36.0 nM
CC(C)c1ccc(-n2cc(C(=O)c3ccccc3N)nn2)cc1 CHEMBL2381477 IC50 41.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1CCN1CCOCC1 CHEMBL4174736 IC50 43.0 nM
CN1CC[C@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@H](F)C1 CHEMBL4160799 IC50 45.0 nM
CCc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 CHEMBL402493 IC50 46.0 nM
COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)N(CCN5CCCC5)C4=O)ccc32)c(C(F)(F)F)c1 CHEMBL4170236 IC50 46.0 nM
COC(=O)c1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2OC)c(Cl)c1 CHEMBL1671964 IC50 47.0 nM
CC(C)(C)OC(=O)N1CCN(c2ccc(C#CCCCC[C@@H]3Cc4cc(O)ccc4[C@H]4CC[C@]5(C)[C@@H](O)CC[C@H]5[C@H]34)cc2)CC1 CHEMBL2326075 IC50 50.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc(-c5ccno5)cc4)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL2326074 IC50 50.0 nM
CCc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 CHEMBL198679 IC50 52.0 nM
C#Cc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 CHEMBL250301 IC50 52.0 nM
Cc1nn(Cc2ccc(Cl)cc2C(F)(F)F)c2ccc(/C=C3\SC(=O)N(CC(=O)NS(=O)(=O)N4CCCC4)C3=O)cc12 CHEMBL4159675 IC50 54.0 nM
COC(=O)c1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2OC)cc1C(F)(F)F CHEMBL1671974 IC50 57.0 nM
C=Cc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 CHEMBL198089 IC50 60.0 nM
COc1cc(/C=C(\C#N)C(=O)Nc2nnc(C(F)(F)F)s2)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL189753 IC50 61.33 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)c2ccccc12 CHEMBL1671981 IC50 62.0 nM
N#Cc1ccc(-c2c3c(nc4ccc(O)cc24)-c2ccc(O)cc2OC3)cc1 CHEMBL437390 IC50 65.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccccc1C(F)(F)F CHEMBL1671972 IC50 68.0 nM
COC(=O)c1cc(C(F)(F)F)ccc1Oc1ccc(/C=C2\SC(=O)NC2=O)cc1OC CHEMBL1671973 IC50 70.0 nM
COC(=O)c1cccc(-n2cc(C(=O)c3ccccc3N)nn2)c1 CHEMBL2381362 IC50 72.0 nM
C#Cc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 CHEMBL440757 IC50 75.0 nM
COC(=O)c1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2OC)c(Br)c1 CHEMBL1671966 IC50 80.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCCCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4067818 IC50 80.0 nM
COc1cccc(-c2c3c(nc4ccc(O)cc24)-c2ccc(O)cc2OC3)c1 CHEMBL398815 IC50 86.0 nM
COc1ccc(-c2c3c(nc4ccc(O)cc24)-c2ccc(O)cc2OC3)cc1 CHEMBL250507 IC50 94.0 nM
CC(C)(C)c1cccc(-n2cc(C(=O)c3ccccc3N)nn2)c1 CHEMBL2381358 IC50 94.0 nM
CCOC(=O)CC(=O)c1ccc(C#CCCCC[C@@H]2Cc3cc(O)ccc3[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@H]23)cc1 CHEMBL2326076 IC50 96.5 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCc4cn(-c5cc6ccc(O)cc6oc5=O)nn4)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL2326070 IC50 100.0 nM
CCOC(=O)c1cccc(-n2cc(C(=O)c3ccccc3N)nn2)c1 CHEMBL2381363 IC50 100.0 nM
CC(=O)c1ccc(Oc2ccc(O)c(C(C)(C)C)c2)c(Cl)c1 CHEMBL4798460 IC50 120.0 nM
CCOC(=O)C(Cc1ccc(C#CCCCC[C@@H]2Cc3cc(O)ccc3[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@H]23)cc1)C(=O)OCC CHEMBL2326069 IC50 126.4 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C(F)(F)F)cc1Br CHEMBL1671967 IC50 140.0 nM
Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1cccc(Cl)c1 CHEMBL250302 IC50 144.0 nM
N#Cc1cccc(-c2c3c(nc4ccc(O)cc24)-c2ccc(O)cc2OC3)c1 CHEMBL398814 IC50 150.0 nM
Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1ccc(Cl)cc1 CHEMBL250505 IC50 160.0 nM
CC(C)c1ccc(-n2cc(C(=O)c3ccc(N)cc3)nn2)cc1 CHEMBL2381350 IC50 160.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C(F)(F)F)cc1Cl CHEMBL1671965 IC50 165.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4095236 IC50 170.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCc6ccc(CNC(=O)CCC7=[N+]8C(=Cc9c(C)cc(C)n9[B-]8(F)F)C=C7)cc6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4066207 IC50 170.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc5ccccc5c4)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL2326073 IC50 175.7 nM
Cc1ccc(-n2cc(CNCC3CCCCC3)c3ccccc32)cc1 CHEMBL478524 IC50 190.0 nM
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 CHEMBL83 IC50 200.0 nM
CCc1cccc(-n2cc(C(=O)c3ccccc3N)nn2)c1 CHEMBL2381354 IC50 200.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCC6CCN(C(=O)CCC7=[N+]8C(=Cc9c(C)cc(C)n9[B-]8(F)F)C=C7)CC6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4089958 IC50 210.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C#N)c1 CHEMBL1671978 IC50 220.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C(F)(F)F)cc1C#N CHEMBL1671963 IC50 240.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL1671955 IC50 270.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc([N+](=O)[O-])c(C(F)(F)F)c1 CHEMBL1671959 IC50 280.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCOCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4087532 IC50 280.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccccc1[N+](=O)[O-] CHEMBL1671956 IC50 290.0 nM
CC(C)c1ccc(-n2cc(C(=O)c3cccc(N)c3)nn2)cc1 CHEMBL2381478 IC50 310.0 nM
Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1ccc(C(F)(F)F)cc1 CHEMBL250506 IC50 319.0 nM
CCC(=O)Nc1ccc(Oc2ccc(Cl)c3ccccc23)c(Cl)c1 CHEMBL4794502 IC50 340.0 nM
CCOc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C(F)(F)F)c1 CHEMBL1671986 IC50 350.0 nM
CCCC(=O)Nc1ccc(Oc2ccc(Cl)c3ccccc23)c(Cl)c1 CHEMBL4744735 IC50 350.0 nM
CC(C)c1ccc(-n2cc(C(=O)c3ccccc3O)nn2)cc1 CHEMBL2381370 IC50 390.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCOCCOCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4105399 IC50 390.0 nM
CCc1nnc(NC(=O)/C(C#N)=C/c2ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)c(OC)c2)s1 CHEMBL186810 IC50 400.0 nM
CC(=O)Nc1ccc(Oc2ccc(Cl)c3ccccc23)cc1 CHEMBL4742675 IC50 420.0 nM
Nc1ccccc1C(=O)c1cn(-c2ccccc2)nn1 CHEMBL2381357 IC50 430.0 nM
COc1cc(/C=C(\C#N)C(=O)Nc2nnc(SC)s2)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL187409 IC50 440.0 nM
COC(=O)c1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2OC)c([N+](=O)[O-])c1 CHEMBL1671957 IC50 470.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C(F)(F)F)c1 CHEMBL1671975 IC50 470.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4078702 IC50 490.0 nM
COc1cc(/C=C(\C#N)C(=O)Nc2nnc(-c3ccccc3)s2)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL186175 IC50 500.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)cc1C#N CHEMBL1671962 IC50 500.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)cc1Cl CHEMBL1671869 IC50 540.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCOCCOCCOCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4079654 IC50 570.0 nM
O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(C(F)(F)F)cc3C(F)(F)F)c2)C(=O)N1CCN1CCCC1 CHEMBL4160018 IC50 580.0 nM
Cc1nc2ccc(Oc3ccc(O)c(C(C)(C)C)c3)cc2n1C CHEMBL4789350 IC50 600.0 nM
CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(OCC)c(C(=O)NCc2ccc(OC)cc2)c1 CHEMBL4168429 IC50 610.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc(CN5CCCCC5)cc4)[C@H]3[C@@H]1CC[C@@H]2O CHEMBL2326071 IC50 637.8 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)cc1C CHEMBL1671977 IC50 640.0 nM
Nc1ccccc1C(=O)c1cn(-c2cccc(-c3ccccc3)c2)nn1 CHEMBL2381359 IC50 650.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCCNC(=O)CCC6=[N+]7C(=Cc8c(C)cc(C)n8[B-]7(F)F)C=C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4102983 IC50 650.0 nM
Cn1c(-c2ccccc2)nc2ccc(Oc3ccc(O)c(C(C)(C)C)c3)cc21 CHEMBL4790878 IC50 660.0 nM
Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(O)c(C(C)(C)C)c3)cc21 CHEMBL4776913 IC50 670.0 nM
c1ccc(-n2cc(CNCC3CCCCC3)c3ccccc32)cc1 CHEMBL477498 IC50 700.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)cc1Br CHEMBL1671968 IC50 720.0 nM
N#Cc1ccc(Oc2ccc(/C=C3\SC(=O)NC3=O)cc2)cc1C(F)(F)F CHEMBL1671984 IC50 720.0 nM
COc1cc(Oc2ccc(C#N)c(C(F)(F)F)c2)ccc1/C=C1\SC(=O)NC1=O CHEMBL1671987 IC50 730.0 nM
COc1cc(/C=C(\C#N)C(=O)Nc2nncs2)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL187944 IC50 750.0 nM
CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nn(Cc5cccc(OCC6CCN(C(=O)CCC7=[N+]8C(=Cc9c(C)cc(C)n9[B-]8(F)F)C=C7)C6)c5)c4s3)C[C@H]2C)nc1 CHEMBL4068864 IC50 770.0 nM
CC(=O)Nc1ccc(Oc2ccc(Cl)c3ccccc23)c(Cl)c1 CHEMBL4751434 IC50 780.0 nM
CCc1nnc(NC(=O)/C(C#N)=C/c2ccc(OCc3cc(F)ccc3C(F)(F)F)c(OC)c2)s1 CHEMBL365887 IC50 800.0 nM
Cc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C(F)(F)F)c1 CHEMBL1671985 IC50 800.0 nM
CC(=O)c1ccc(Oc2ccc(O)c(C(C)(C)C)c2)cc1 CHEMBL4760865 IC50 800.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C)c1 CHEMBL1671976 IC50 890.0 nM
Cc1ccccc1C(=O)c1cn(-c2ccc(C(C)C)cc2)nn1 CHEMBL2381372 IC50 890.0 nM
Cn1c(COc2ccccc2)nc2ccc(Oc3ccc(O)c(C(C)(C)C)c3)cc21 CHEMBL4789973 IC50 890.0 nM
CC(C)c1ccc(-n2cc(C(=O)c3ccccc3[N+](=O)[O-])nn2)cc1 CHEMBL2381371 IC50 900.0 nM
CCc1nnc(NC(=O)/C(C#N)=C/c2ccc(OCc3ccc(F)cc3C(F)(F)F)c(OC)c2)s1 CHEMBL361308 IC50 920.0 nM
Cc1ccc(C)c(-c2cc(-c3ccc(O)cc3)nn2C)c1 CHEMBL1671990 EC50 1000.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc([N+](=O)[O-])cc1C#N CHEMBL1671960 IC50 1000.0 nM
COc1cc(/C=C2\SC(=O)NC2=O)ccc1Oc1ccc(C#N)cc1 CHEMBL1671980 IC50 1000.0 nM
CC(=O)Nc1ccc(Oc2ccc(O)c(C(C)(C)C)c2)c(Cl)c1 CHEMBL4783029 IC50 1000.0 nM