O=C(c1nc2cccc(Cl)c2nc1O)N1CCCC1Cc1cc(Cl)cc(Cl)c1 CHEMBL5272139 Ki 0.1 nM
[3H]c1c(Cl)ccc(COc2cccc(C(=O)O)c2OCc2ccc(Cl)c([3H])c2Cl)c1Cl CHEMBL247298 Ki 2.0 nM
O=C(O)[C@@H](O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl CHEMBL378857 Ki 2.5 nM
Cn1c(-c2ccccc2-c2cccc(NCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL245282 Ki 2.7 nM
CCn1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL245284 Ki 3.3 nM
CCn1c(-c2ccccc2-c2cccc(NCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL245653 Ki 3.4 nM
CCc1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)oc(-c2ccccc2)c1-c1ccccc1 CHEMBL247529 Ki 3.5 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(OCC(=O)O)c1 CHEMBL247920 Kd 4.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3cccs3)n(-c3ccc(Cl)cc3)n2)c1 CHEMBL1782966 Ki 5.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 CHEMBL126078 Ki 6.0 nM
CCC(Oc1cccc(-c2ccccc2-c2cc(-c3cccs3)n(-c3ccc(Cl)cc3)n2)c1)C(=O)O CHEMBL1782968 Ki 6.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccco3)n(-c3ccc(Cl)cc3)n2)c1 CHEMBL1782965 Ki 7.0 nM
S=c1[nH]nc(-c2c(N3CCCCC3)nc3ccc(Cl)cc3c2-c2ccccc2)o1 CHEMBL3970105 Ki 7.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2nc(-c3ccccc3)c(-c3ccccc3)n2CCF)c1 CHEMBL397385 Ki 8.7 nM
O=C(O)COc1cccc(-c2ccccc2-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)c1 CHEMBL248144 Ki 9.3 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3918729 IC50 10.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3919426 IC50 10.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C(F)(F)F)no2)c1C1CC1 CHEMBL3896829 IC50 10.0 nM
O=C(O)C1=C(C(=O)Nc2sccc2-c2nc(C3CC3)no2)CCC1 CHEMBL3905766 IC50 10.0 nM
Cc1c(Cl)cccc1NCc1cc(=O)n2nc(-c3ccccc3)nc2[nH]1 CHEMBL4581404 Kd 10.0 nM
Cc1cc(-c2c3c(nc(C4CCCC4)c2-c2nnn[nH]2)CCC(C)C3)ccn1 CHEMBL5278127 IC50 10.0 nM
Cc1cc(-c2c3c(nc(C4(C)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 CHEMBL5281007 IC50 10.0 nM
Cc1c(Cl)cccc1OCc1cc(=O)n2nc(-c3ccccc3)nc2[nH]1 CHEMBL4560388 Kd 10.0 nM
Clc1ccc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1 CHEMBL3959018 Ki 11.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)ns2)c1C CHEMBL3915309 IC50 11.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)c(-c3ccccc3)[nH]2)c1 CHEMBL394966 Ki 12.0 nM
CC(C)c1nc2ccc(Cl)cc2c(-c2ccccc2)c1C(=O)O CHEMBL3947458 Ki 12.0 nM
Cn1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL396698 Ki 13.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)n2)c1 CHEMBL1782964 Ki 13.0 nM
Cc1cc(Cl)cc2c(-c3ccccc3)c(C(=O)O)c(N3CCCCC3)nc12 CHEMBL3950316 Ki 13.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)ns1 CHEMBL3914116 IC50 13.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1 CHEMBL3923099 IC50 13.0 nM
Fc1cc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2cc1Cl CHEMBL5268623 IC50 13.0 nM
CCN(CC)c1nc2cc(F)c(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5268944 IC50 13.0 nM
Cc1csc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3964149 IC50 15.0 nM
O=C(O)Cc1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl CHEMBL212860 Ki 16.0 nM
O=C(O)c1c(N2CCCCC2)nc2c(Cl)cc(Cl)cc2c1-c1ccccc1 CHEMBL3971182 Ki 16.0 nM
CC(C)c1cccc(-c2c(C(=O)O)c(N(C)C)nc3ccc(Cl)cc23)c1 CHEMBL3979347 Ki 16.0 nM
CCC(CC)c1nc2cc(F)c(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5274115 IC50 17.0 nM
O=C(O)CNc1cccc(-c2ccccc2-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)c1 CHEMBL248145 Ki 18.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCCC2)c1-c1nc(C2CC2)ns1 CHEMBL3920664 IC50 19.0 nM
O=C(O)C1=C(C(=O)Nc2scc(C3CC3)c2-c2nc(C3CC3)no2)CCC1 CHEMBL3903803 IC50 19.2 nM
O=c1[nH]nc(-c2c(N3CCCCC3)nc3ccc(Cl)cc3c2-c2ccccc2)o1 CHEMBL3889982 Ki 20.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3979971 IC50 20.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C1CC1 CHEMBL3896498 IC50 20.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C1CC1 CHEMBL3967672 IC50 20.0 nM
Cc1cc(-c2nc(C3CC3)no2)c(NC(=O)C2=C(C(=O)O)CCC2)s1 CHEMBL3928329 IC50 20.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C(F)(F)F CHEMBL3914622 IC50 20.0 nM
O=c1cc(CNc2cccc(Cl)c2C2CC2)[nH]c2nc(-c3ccccc3)nn12 CHEMBL4547281 Kd 20.0 nM
Cc1cc(-c2c3c(nc(C4(CO)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 CHEMBL5287082 IC50 20.0 nM
CCCCCC1CCc2nc(C3(COC)CCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2C1 CHEMBL5278217 IC50 20.0 nM
O=c1c(Cl)c(COc2cccc(Cl)c2C2CC2)[nH]c2nc(-c3ccccc3)nn12 CHEMBL5282728 Kd 20.0 nM
O=C(O)C1=C(C(=O)Nc2scc(C(F)(F)F)c2-c2nc(C3CC3)no2)CCC1 CHEMBL3897486 IC50 20.5 nM
Cc1sc(NC(=O)C2=C(C(=O)O)COCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3919746 IC50 21.0 nM
O=C(O)c1c(N2CCCCC2)nc2ccc(Cl)cc2c1-c1ccccc1 CHEMBL3941588 Ki 22.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C3CC3)c2C)n1 CHEMBL3957282 IC50 22.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C)c2C)n1 CHEMBL3986878 IC50 23.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C)n1 CHEMBL3950827 IC50 25.0 nM
CCN(CC)c1nc2ccc(C(F)(F)F)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5287141 IC50 25.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)ns2)c1C CHEMBL3920801 IC50 27.0 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(C(O)C(=O)O)c1 CHEMBL248120 Ki 28.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C3CC3)c2C)n1 CHEMBL3938613 IC50 29.0 nM
Cc1n[nH]c(C)c1-c1c(-c2cccc(OC(C)C)c2)n(CCC(=O)O)c2ccc(C3CC3)cc12 CHEMBL3814634 Ki 30.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C(F)(F)F)no2)c1C1CC1 CHEMBL3913234 IC50 30.0 nM
CCc1nc2ccc(Cl)cc2c(-c2ccccc2)c1C(=O)O CHEMBL5287034 Ki 30.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C3CC3)c2C)n1 CHEMBL3929717 IC50 31.0 nM
O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)n(-c3ccccc3)n2)c1 CHEMBL1782963 Ki 32.0 nM
FC(F)(F)c1ccc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1 CHEMBL5272220 IC50 33.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccccc1 CHEMBL4632412 Kd 34.4 nM
O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)c(-c3ccccc3)o2)c1 CHEMBL246902 Ki 36.0 nM
CCN(C)c1nc2c(Cl)cc(Cl)cc2c(-c2ccccc2)c1C(=O)O CHEMBL5266709 IC50 36.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2c(c1)CCO2 CHEMBL4632369 IC50 37.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C CHEMBL3891355 IC50 40.0 nM
O=C(O)C1=C(C(=O)Nc2sc(C3CC3)cc2-c2nc(C3CC3)no2)CCC1 CHEMBL3981828 IC50 40.8 nM
O=C(O)c1c(C2CC2)nc2ccc(Cl)cc2c1-c1ccccc1 CHEMBL5279204 IC50 42.0 nM
COc1cccc(Nc2ccccc2C(=O)O)c1-c1ccccc1 CHEMBL4633440 Kd 43.9 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C)c2C)n1 CHEMBL3943278 IC50 44.0 nM
CCN(C)c1nc2ccc(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5266531 IC50 45.0 nM
O=C(O)c1cccc2c3c(n(Cc4ccccc4C(F)(F)F)c12)CCCCC3 CHEMBL460750 IC50 49.0 nM
COC(C(=O)O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl CHEMBL437489 Ki 50.0 nM
O=C(Nc1cc(Cl)cc(Cl)c1-c1ccccc1)NC1(C(=O)O)CCCC1 CHEMBL3953175 IC50 50.0 nM
O=C(O)CCCCOc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)o1 CHEMBL116533 Ki 58.0 nM
Cc1c(-c2nsc(N(C)C)n2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3962973 IC50 58.1 nM
CNc1ccc(Nc2ccccc2C(=O)O)c(-c2ccc3c(c2)CCO3)c1Cl CHEMBL4638396 Kd 58.4 nM
O=C(Nc1cc(Cl)c(F)cc1-c1ccccc1)NC1(C(=O)O)CC1 CHEMBL3969505 IC50 60.0 nM
CNc1ccc(Nc2ccccc2C(=O)O)c(-c2ccccc2)c1Cl CHEMBL4644810 Kd 60.1 nM
NC(=O)c1cccc(Cn2c3c(c4cccc(C(=O)O)c42)CCCCC3)c1 CHEMBL516023 IC50 69.0 nM
Cc1noc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C2CC2)n1 CHEMBL3975095 IC50 70.0 nM
O=C(Nc1cc(Cl)cc(Cl)c1-c1ccccc1)NC1(C(=O)O)CC1 CHEMBL3916530 IC50 80.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCCC2)c(-c2nc(C3CC3)ns2)c1C CHEMBL3952008 IC50 85.0 nM
Cc1c(C2COC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3933786 IC50 90.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2occc2c1 CHEMBL4644782 Kd 90.1 nM
O=C(O)c1cccc2c3c(n(Cc4ccccc4)c12)CCCCC3 CHEMBL514969 IC50 96.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2[nH]ncc2c1 CHEMBL4640209 Kd 96.2 nM
NC(=O)c1ccccc1Cn1c2c(c3cccc(C(=O)O)c31)CCCCC2 CHEMBL474944 IC50 98.0 nM
COc1cnccc1-c1c(-c2ccccc2)n(CCC(=O)O)c2ccc(C3CC3)cc12 CHEMBL3813892 Ki 100.0 nM
O=C(Nc1cc(Cl)c(F)cc1-c1ccccc1)NC1(C(=O)O)CCCC1 CHEMBL3944468 IC50 100.0 nM
Cc1nc2ccc(Cl)cc2c(-c2ccccc2)c1C(=O)O CHEMBL1738980 Ki 100.0 nM
Cc1c(C2COC2)sc(NC(=O)C2=C(C(=O)O)CCCC2)c1-c1nc(C2CC2)no1 CHEMBL3890150 IC50 105.0 nM
O=C(O)c1ccccc1Nc1ccccc1-c1ccccc1 CHEMBL4641484 Ki 109.3 nM
c1cc(-c2c3c(nc(C4CCCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 CHEMBL5279662 IC50 110.0 nM
O=C(O)CCn1c(-c2ccccc2)c(-c2ccccc2)c2cc(C3CC3)ccc21 CHEMBL3814575 Ki 120.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2nonc2c1 CHEMBL4643718 Kd 125.5 nM
CC(C)Cn1c(-c2ccccc2-c2cccc(NCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL245857 Ki 130.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2c(c1)OCO2 CHEMBL4644705 Kd 136.2 nM
O=C(Nc1cc(Cl)ccc1-c1ccccc1)NC1(C(=O)O)CC1 CHEMBL3967738 IC50 140.0 nM
O=C(Nc1cc(Cl)ccc1-c1ccc(F)cc1)NC1(C(=O)O)CCCC1 CHEMBL3930938 IC50 140.0 nM
Cc1noc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C)c2C2CC2)n1 CHEMBL3903176 IC50 140.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2ccccc2c1 CHEMBL4642358 Ki 149.7 nM
O=S(=O)(O)c1cccc2cccc(Nc3ccccc3)c12 CHEMBL285527 Kd 150.0 nM
O=C(Nc1cc(Cl)ccc1-c1ccccc1)NC1(C(=O)O)CCCC1 CHEMBL3958926 IC50 150.0 nM
O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1-c1ccccc1 CHEMBL4646688 Ki 164.1 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O CHEMBL15594 Kd 180.0 nM
Cc1cccc(Nc2ccccc2C(=O)O)c1-c1ccccc1 CHEMBL4639338 Ki 182.4 nM
CCCCCCCC/C=C\CCCCCCCC(=O)O CHEMBL8659 Ki 185.0 nM
O=C(O)C1=C(C(=O)Nc2sccc2-c2ccccc2)CCC1 CHEMBL3972884 IC50 200.0 nM
COc1ccc(S(=O)(=O)Nc2cc(C(=O)O)ccc2F)c2ccccc12 CHEMBL4295114 Ki 200.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)no1 CHEMBL3890665 IC50 210.0 nM
COc1ccc(S(=O)(=O)Nc2ccc(F)c(C(=O)O)c2)c2ccccc12 CHEMBL4283424 Ki 210.0 nM
Cc1sc(NC(=O)N2CCC[C@@H]2C(=O)O)c(-c2nc(C(F)(F)F)no2)c1C CHEMBL4113722 IC50 217.0 nM
COc1ccc(S(=O)(=O)Nc2cc(C(=O)O)c(F)cc2F)c2ccccc12 CHEMBL4280127 Ki 230.0 nM
Cc1sc(NC(=O)C2CCCCC2C(=O)O)c(-c2nc(C3CC3)no2)c1C CHEMBL3986323 IC50 244.0 nM
O=C(O)C1=C(C(=O)Nc2sc(CC(F)(F)F)cc2-c2nc(C3CC3)no2)CCC1 CHEMBL3973942 IC50 247.6 nM
CCOC(=O)c1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3899095 IC50 250.0 nM
O=C(O)c1ccccc1Nc1cccc(Br)c1-c1ccccc1 CHEMBL4639506 Ki 262.9 nM
O=C(O)c1cc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)ccc1O CHEMBL5416572 Ki 280.0 nM
O=C(O)C1C2CC=CC2c2cc(Br)cc3c2N1CC1CC=CC31 CHEMBL3828508 Ki(app) 290.0 nM
O=C(Nc1ccc(Cl)cc1-c1ccc(F)cc1)NC1(C(=O)O)CC1 CHEMBL3980900 IC50 290.0 nM
O=C(O)c1cc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)ccc1[N+](=O)[O-] CHEMBL5406503 Ki 300.0 nM
Cc1noc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C)c2C2CC2)n1 CHEMBL3927654 IC50 310.0 nM
Cc1ccc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)cc1C(=O)O CHEMBL5400471 Ki 320.0 nM
O=C(Nc1cc(Cl)ccc1-c1ccc(F)cc1)NC1(C(=O)O)CC1 CHEMBL3958454 IC50 330.0 nM
CCc1c(-c2ccccc2)c(-c2ccc(F)cc2)nn1-c1ccccc1-c1cccc(OCC(=O)O)c1 CHEMBL5285216 IC50 330.0 nM
CS(=O)(=O)Nc1ccc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)cc1C(=O)O CHEMBL5395019 Ki 330.0 nM
CCCCCCCCCCCCCCCC(=O)O CHEMBL82293 Ki 336.0 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1ccccc1OCC(=O)O CHEMBL4280900 Ki 350.0 nM
O=C(O)Cc1cccc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)c1 CHEMBL5401901 Ki 350.0 nM
Cc1cc2c3c(c1)C1C=CCC1C(C(=O)O)N3CC1CC=CC21 CHEMBL3827483 Ki(app) 380.0 nM
COc1ccc(S(=O)(=O)Nc2cccc(C(=O)O)c2)c2ccccc12 CHEMBL4285684 Ki 400.0 nM
CCCn1c2c(c3cccc(C(=O)O)c31)CCCCC2 CHEMBL516469 IC50 430.0 nM
Nc1ccc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)cc1C(=O)O CHEMBL5410855 Ki 430.0 nM
O=C(O)c1cccc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)c1 CHEMBL5409997 Ki 480.0 nM
O=C(O)c1cc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)ccc1C(F)(F)F CHEMBL5419463 Ki 510.0 nM
O=C(Nc1cc(C(F)(F)F)ccc1-c1ccccc1)NC1(C(=O)O)CCCC1 CHEMBL3922017 IC50 520.0 nM
COc1cccc(Cn2c3c(c4cccc(C(=O)O)c42)CCCC3)c1 CHEMBL514666 IC50 550.0 nM
O=C(O)c1cc(O)cc(-c2cccc(Cl)c2-c2ccc3c(c2)CCO3)c1 CHEMBL5426506 Ki 550.0 nM
O=C(O)CCCn1c2ccccc2c2ccccc21 CHEMBL185595 IC50 570.0 nM
COc1ccc(S(=O)(=O)Nc2cccc(CCC(=O)O)c2)c2ccccc12 CHEMBL4282996 Ki 580.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3-c3ccc4c(c3)CCO4)cc21 CHEMBL5425832 Ki 580.0 nM
O=C(O)c1cccc2c3c(n(Cc4ccccc4)c12)CCCC3 CHEMBL452596 IC50 590.0 nM
COc1ccc(S(=O)(=O)NCCCCC(=O)O)c2ccccc12 CHEMBL4292481 Ki 590.0 nM
COc1ccc(CSc2nc(O)cc(C(F)(F)F)n2)cc1 CHEMBL184136 IC50 600.0 nM
COc1ccccc1Cn1c2c(c3cccc(C(=O)O)c31)CCCC2 CHEMBL475549 IC50 600.0 nM
Cc1cc(C)c2c3c1C1C=CCC1CN3C(C(=O)O)C1CC=CC21 CHEMBL3827900 Ki(app) 610.0 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(C(=O)O)c1 CHEMBL394440 Ki 650.0 nM
CCCn1c2c(c3cccc(C(=O)O)c31)CCCC2 CHEMBL501361 IC50 670.0 nM
COC(=O)c1sc(-c2cccs2)cc1NC(=O)/C=C/C(=O)O CHEMBL1077990 Ki 670.0 nM
O=C(O)C1C2CC=CC2c2cc(Cl)cc3c2N1CC1CC=CC31 CHEMBL3828043 Ki(app) 690.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3-c3ccc4occc4c3)cc21 CHEMBL5398758 Ki 690.0 nM
O=C(O)c1cccc2c3c(n(Cc4ccccc4F)c12)CCCCC3 CHEMBL518180 IC50 710.0 nM
O=C(O)c1cccc2c3c(n(Cc4cccc(F)c4)c12)CCCCC3 CHEMBL460749 IC50 720.0 nM
O=C(O)c1cc(-c2cccc(Cl)c2-c2ccc3occc3c2)ccc1C(F)(F)F CHEMBL5420436 Ki 720.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3-c3ccc4ocnc4c3)cc21 CHEMBL5406225 Ki 740.0 nM
O=C(O)c1ccc2c3c(n(Cc4ccccc4)c2c1)CCCC3 CHEMBL459901 IC50 750.0 nM
O=C(Nc1ccc(Cl)cc1-c1ccc(F)cc1)NC1(C(=O)O)CCCC1 CHEMBL3938704 IC50 750.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3OCC3CCC3)cc21 CHEMBL5430313 Ki 750.0 nM
COc1ccc(S(=O)(=O)NCc2ccc(C(=O)O)cc2)c2ccccc12 CHEMBL4278392 Ki 760.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3-c3ccc4[nH]ncc4c3)cc21 CHEMBL5425281 Ki 760.0 nM
O=C(O)c1cccc2c3c(n(Cc4ccc(F)cc4)c12)CCCCC3 CHEMBL518181 IC50 780.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3OC3CCC3)cc21 CHEMBL5424790 Ki 790.0 nM
O=C(O)C1CCc2ccc(-c3cccc(Cl)c3-c3ccc4c(c3)OCO4)cc21 CHEMBL5405334 Ki 790.0 nM
O=C(O)CCCCn1c2ccccc2c2ccccc21 CHEMBL184795 IC50 800.0 nM
O=C(Nc1cc(Cl)ccc1-c1ccccc1)NC1(C(=O)O)CCC1 CHEMBL3893057 IC50 810.0 nM
COc1ccc(S(=O)(=O)Nc2cc(Cl)cc(C(=O)O)c2)c2ccccc12 CHEMBL4284461 Ki 820.0 nM
CN(C)c1ccc(Nc2ccccc2C(=O)O)c(-c2ccccc2)c1Cl CHEMBL4637279 Ki 826.4 nM
O=C(O)c1cccc2c3c(n(Cc4ccc(F)cc4)c12)CCCC3 CHEMBL515905 IC50 830.0 nM
COc1ccc(S(=O)(=O)Nc2cccc(CC(=O)O)c2)c2ccccc12 CHEMBL4293529 Ki 840.0 nM
COc1ccc(Cl)cc1NCc1cc(=O)n2nc(-c3ccccc3)nc2[nH]1 CHEMBL4568855 Kd 860.0 nM
COc1cccc(Cl)c1NCc1cc(=O)n2nc(-c3ccccc3)nc2[nH]1 CHEMBL5282255 Kd 860.0 nM
O=C(Nc1ccc(Cl)cc1-c1ccccc1)NC1(C(=O)O)CC1 CHEMBL3943391 IC50 890.0 nM
Cc1c(C)c(C)c(S(=O)(=O)NCCCCC(=O)O)c(C)c1C CHEMBL4280730 Ki 910.0 nM
O=C(O)c1cc(-c2cccc(Cl)c2-c2ccc3nonc3c2)ccc1C(F)(F)F CHEMBL5433272 Ki 920.0 nM
COc1ccc(S(=O)(=O)Nc2cc(C(=O)O)ccc2Cl)c2ccccc12 CHEMBL4279007 Ki 930.0 nM
O=C(Nc1cc(C(F)(F)F)ccc1-c1ccccc1)NC1(C(=O)O)CC1 CHEMBL3968270 IC50 950.0 nM
O=C(O)c1cccc2c3c(n(Cc4ccccc4)c12)CCC3 CHEMBL459902 IC50 970.0 nM
O=C(CSc1nc(O)cc(C(F)(F)F)n1)N1CCCCC1 CHEMBL360376 IC50 1000.0 nM
O=C(O)CSCC(=O)Nc1cc(Cl)cc(Cl)c1 CHEMBL1085570 IC50 1000.0 nM
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O CHEMBL267476 IC50 1000.0 nM