[3H]c1c(Cl)ccc(COc2cccc(C(=O)O)c2OCc2ccc(Cl)c([3H])c2Cl)c1Cl CHEMBL247298 Ki 2.0 nM
O=C(O)Cc1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl CHEMBL212860 Ki 3.0 nM
COC(C(=O)O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl CHEMBL437489 Ki 9.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1 CHEMBL3923099 IC50 16.0 nM
CCCCCC1CCc2nc(C3(COC)CCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2C1 CHEMBL5278217 IC50 20.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)ns2)c1C CHEMBL3920801 IC50 22.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)ns1 CHEMBL3914116 IC50 22.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3918729 IC50 30.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C1CC1 CHEMBL3896498 IC50 30.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3919426 IC50 30.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C3CC3)c2C)n1 CHEMBL3957282 IC50 30.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C(F)(F)F)no2)c1C1CC1 CHEMBL3896829 IC50 30.0 nM
Cc1cc(-c2c3c(nc(C4(CO)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 CHEMBL5287082 IC50 30.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C3CC3)c2C)n1 CHEMBL3938613 IC50 31.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C)c2C)n1 CHEMBL3986878 IC50 31.0 nM
O=C(O)[C@@H](O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl CHEMBL378857 Ki 33.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)ns2)c1C CHEMBL3915309 IC50 38.0 nM
O=C(O)C1=C(C(=O)Nc2scc(C3CC3)c2-c2nc(C3CC3)no2)CCC1 CHEMBL3903803 IC50 38.8 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C3CC3)c2C)n1 CHEMBL3929717 IC50 39.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C1CC1 CHEMBL3967672 IC50 40.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCCC2)c1-c1nc(C2CC2)ns1 CHEMBL3920664 IC50 40.0 nM
Cc1cc(-c2c3c(nc(C4(C)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 CHEMBL5281007 IC50 40.0 nM
O=C(O)C1=C(C(=O)Nc2scc(C(F)(F)F)c2-c2nc(C3CC3)no2)CCC1 CHEMBL3897486 IC50 40.9 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C)n1 CHEMBL3950827 IC50 41.0 nM
Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)no1 CHEMBL3890665 IC50 50.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C CHEMBL3891355 IC50 50.0 nM
CCN(CC)c1nc2cc(F)c(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5268944 IC50 51.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C(F)(F)F)no2)c1C1CC1 CHEMBL3913234 IC50 60.0 nM
Cc1c(C2COC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3933786 IC50 60.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C(F)(F)F CHEMBL3914622 IC50 60.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCCC2)c(-c2nc(C3CC3)ns2)c1C CHEMBL3952008 IC50 61.0 nM
Fc1cc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2cc1Cl CHEMBL5268623 IC50 62.0 nM
CCN(CC)c1nc2ccc(C(F)(F)F)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5287141 IC50 64.0 nM
Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C)c2C)n1 CHEMBL3943278 IC50 66.0 nM
Cc1cc(-c2c3c(nc(C4CCCC4)c2-c2nnn[nH]2)CCC(C)C3)ccn1 CHEMBL5278127 IC50 70.0 nM
CCC(CC)c1nc2cc(F)c(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5274115 IC50 80.0 nM
Clc1ccc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1 CHEMBL3959018 Ki 86.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)CCCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3979971 IC50 90.0 nM
Cc1cc(-c2c3c(nc(C4CCCCC4)c2-c2nnn[nH]2)CCC(C(F)(F)F)C3)ccn1 CHEMBL5270510 IC50 90.0 nM
FC(F)(F)c1ccc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1 CHEMBL5272220 IC50 96.0 nM
Cc1csc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3964149 IC50 98.6 nM
Cc1cc(Cl)cc2c(-c3ccccc3)c(C(=O)O)c(N3CCCCC3)nc12 CHEMBL3950316 Ki 100.0 nM
O=C(O)c1c(N2CCCCC2)nc2c(Cl)cc(Cl)cc2c1-c1ccccc1 CHEMBL3971182 Ki 120.0 nM
Cc1noc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C2CC2)n1 CHEMBL3975095 IC50 120.0 nM
O=C1Cc2ccc(-c3cccc(OC(=O)[C@H]4[C@@H](c5ccccc5)[C@H](C(=O)O)[C@@H]4c4ccccc4)c3)cc2N1 CHEMBL5399759 Ki 120.0 nM
O=C(O)C1=C(C(=O)Nc2sc(C3CC3)cc2-c2nc(C3CC3)no2)CCC1 CHEMBL3981828 IC50 125.8 nM
CCOC(=O)c1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3899095 IC50 130.0 nM
S=c1[nH]nc(-c2c(N3CCCCC3)nc3ccc(Cl)cc3c2-c2ccccc2)o1 CHEMBL3970105 Ki 133.0 nM
Cc1sc(NC(=O)C2=C(C(=O)O)COCC2)c(-c2nc(C3CC3)no2)c1C CHEMBL3919746 IC50 143.0 nM
O=c1[nH]nc(-c2c(N3CCCCC3)nc3ccc(Cl)cc3c2-c2ccccc2)o1 CHEMBL3889982 Ki 167.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)O[C@@H]2CCCC[C@H]2c2ccccc2)[C@H]1c1ccccc1 CHEMBL4288603 Ki 180.0 nM
CCN(C)c1nc2ccc(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 CHEMBL5266531 IC50 182.0 nM
CCN(C)c1nc2c(Cl)cc(Cl)cc2c(-c2ccccc2)c1C(=O)O CHEMBL5266709 IC50 183.0 nM
O=C(O)C1=C(C(=O)Nc2sc(CC(F)(F)F)cc2-c2nc(C3CC3)no2)CCC1 CHEMBL3973942 IC50 189.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)O[C@H]2CCCC[C@@H]2c2ccccc2)[C@H]1c1ccccc1 CHEMBL4277947 Ki 200.0 nM
Cc1c(C2COC2)sc(NC(=O)C2=C(C(=O)O)CCCC2)c1-c1nc(C2CC2)no1 CHEMBL3890150 IC50 227.0 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(C(=O)O)c1 CHEMBL394440 Ki 240.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)O CHEMBL8659 Ki 248.0 nM
CCc1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)oc(-c2ccccc2)c1-c1ccccc1 CHEMBL247529 Ki 290.0 nM
Cc1noc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C)c2C2CC2)n1 CHEMBL3927654 IC50 300.0 nM
Cc1noc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C)c2C2CC2)n1 CHEMBL3903176 IC50 320.0 nM
N#Cc1ccc(-c2ccccc2)cc1OC(=O)[C@H]1[C@@H](c2ccccc2)[C@H](C(=O)O)[C@@H]1c1ccccc1 CHEMBL5430100 Ki 320.0 nM
Cc1c(-c2nsc(N(C)C)n2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 CHEMBL3962973 IC50 330.0 nM
COc1ccccc1[C@H]1[C@H](C(=O)O)[C@H](c2ccccc2OC)[C@H]1C(=O)Oc1cc(-c2ccccc2)ccc1C#N CHEMBL5404205 Ki 330.0 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(OCC(=O)O)c1 CHEMBL247920 Ki 350.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)Oc2cccc(-c3ccc4c(c3)OCO4)c2)[C@H]1c1ccccc1 CHEMBL5394488 Ki 360.0 nM
Cc1cc(-c2nc(C3CC3)no2)c(NC(=O)C2=C(C(=O)O)CCC2)s1 CHEMBL3928329 IC50 380.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2occc2c1 CHEMBL4644782 Ki 430.0 nM
Cc1sc(NC(=O)C2CCCCC2C(=O)O)c(-c2nc(C3CC3)no2)c1C CHEMBL3986323 IC50 453.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2[nH]ncc2c1 CHEMBL4640209 Ki 490.0 nM
O=C(O)c1c(N2CCCCC2)nc2ccc(Cl)cc2c1-c1ccccc1 CHEMBL3941588 Ki 490.0 nM
N#Cc1ccc(-c2ccccc2)cc1NC(=O)[C@H]1[C@@H](c2ccccc2)[C@H](C(=O)O)[C@@H]1c1ccccc1 CHEMBL5422779 Ki 500.0 nM
CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(C(O)C(=O)O)c1 CHEMBL248120 Ki 550.0 nM
COc1ccccc1[C@H]1[C@H](C(=O)O)[C@H](c2ccccc2OC)[C@H]1C(=O)Oc1cccc2ccccc12 CHEMBL4287414 Ki 550.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2nonc2c1 CHEMBL4643718 Ki 600.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2ccccc2c1 CHEMBL4642358 Ki 600.0 nM
COc1ccccc1[C@H]1[C@H](C(=O)O)[C@H](c2ccccc2OC)[C@H]1C(=O)O[C@@H]1CCCC[C@H]1c1ccccc1 CHEMBL4284051 Ki 680.0 nM
O=C(O)[C@H]1[C@@H](c2ccccc2)[C@H](C(=O)Oc2cccc3ccccc23)[C@@H]1c1ccccc1 CHEMBL4289745 Ki 710.0 nM
COc1ccccc1[C@H]1[C@H](C(=O)O)[C@H](c2ccccc2OC)[C@H]1C(=O)Oc1cccc(-c2ccc3c(c2)OCO3)c1 CHEMBL5436742 Ki 720.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)Nc2cccc(-c3ccc4c(c3)OCO4)c2)[C@H]1c1ccccc1 CHEMBL5396730 Ki 760.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)Oc2ccccc2-c2ccccc2)[C@H]1c1ccccc1 CHEMBL4287117 Ki 770.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)Oc2cccc3ccccc23)[C@H]1c1ccccc1 CHEMBL4281879 Ki 790.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)Oc2cc(Cl)c(Cl)cc2Cl)[C@H]1c1ccccc1 CHEMBL4293939 Ki 800.0 nM
CCCCCCCCCCCCCCCC(=O)O CHEMBL82293 Kd 802.0 nM
O=C(O)C1C(c2ccccc2)C(C(=O)Oc2cccc3ccccc23)C1c1ccccc1 CHEMBL4292072 Ki 810.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2c(c1)CCO2 CHEMBL4632369 Ki 820.0 nM
CCn1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL245284 Ki 830.0 nM
Cn1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 CHEMBL396698 Ki 830.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2)[C@H](C(=O)Oc2cccc(-c3ccccc3)c2)[C@H]1c1ccccc1 CHEMBL4295043 Ki 850.0 nM
COc1ccccc1[C@H]1[C@H](C(=O)O)[C@H](c2ccccc2OC)[C@H]1C(=O)OCc1ccccc1-c1ccccc1 CHEMBL5416088 Ki 870.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccccc1 CHEMBL4632412 Ki 880.0 nM
O=C(O)C1=C(C(=O)Nc2sccc2-c2nc(C3CC3)no2)CCC1 CHEMBL3905766 IC50 890.0 nM
C#Cc1cccc(OC(=O)[C@H]2[C@@H](c3ccccc3)[C@H](C(=O)O)[C@@H]2c2ccccc2)c1 CHEMBL4291624 Ki 890.0 nM
O=C(O)[C@H]1[C@H](c2ccccc2Cl)[C@H](C(=O)OCC2c3ccccc3-c3ccccc32)[C@H]1c1ccccc1Cl CHEMBL4292323 Ki 890.0 nM
COc1ccccc1[C@H]1[C@H](C(=O)O)[C@H](c2ccccc2OC)[C@@H]1C(=O)Oc1cccc(-c2ccc3c(c2)OCO3)c1 CHEMBL5403530 Ki 890.0 nM
CC(=O)Nc1ccc2c(OC(=O)[C@H]3[C@@H](c4ccccc4)[C@H](C(=O)O)[C@@H]3c3ccccc3)cccc2c1 CHEMBL4278244 Ki 970.0 nM