C[C@H]1[C@H](c2ccc(F)cc2)OC(=O)N1c1cc(Cl)cc(C#N)c1 CHEMBL4084502 IC50 0.52 nM
O=c1c(-c2cnn(CCC(F)(F)F)c2)c(C(F)(F)F)nc2ccc(F)cn12 CHEMBL4856454 IC50 1.1 nM
Cc1cc2nc(C(F)(F)F)c(-c3cnn(CC(F)(F)C(F)(F)F)c3)c(=O)n2cc1Cl CHEMBL4879015 IC50 1.2 nM
C[C@H]1[C@H](c2ccc(F)cc2)OC(=O)N1c1cc(C#N)cc(C#N)c1 CHEMBL4064555 IC50 1.5 nM
C[C@@H]1[C@@H](c2ccc(F)cc2)OC(=O)N1c1cc(C#N)cc(C#N)c1 CHEMBL5278664 IC50 1.5 nM
CN(C(=O)F)c1ccn2c(=O)c(-c3cnn(CC(F)(F)C(F)(F)F)c3)c(C(F)(F)F)nc2c1 CHEMBL4874614 IC50 1.6 nM
Cc1ccc2nc(C(F)(F)F)c(-c3cnn(CC(F)(F)C(F)(F)F)c3)c(=O)n2c1 CHEMBL4872983 IC50 1.7 nM
CC(=O)NCCSc1nc2cscc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1 CHEMBL4439992 IC50 1.9 nM
O=c1c(-c2cnn(CC(F)(F)C(F)(F)F)c2)c(C(F)(F)F)nc2ccc(F)cn12 CHEMBL4855704 IC50 2.1 nM
O=c1c(-c2cnn(CCC(F)(F)F)c2)c(C(F)(F)F)nc2ccc(Cl)cn12 CHEMBL4868627 IC50 2.4 nM
C[C@H]1[C@H](c2ccc(F)cc2)OC(=O)N1c1cc(F)cc(C#N)c1 CHEMBL4102458 IC50 3.7 nM
COc1cccc(N2CC(c3ccc(F)cc3)OC2=O)c1 CHEMBL4060775 IC50 4.1 nM
Clc1cccc(Nc2n[nH]c3ccc(Cl)cc23)c1 CHEMBL3608796 IC50 5.0 nM
Cc1ccc2[nH]nc(Nc3cccc(Cl)c3)c2c1 CHEMBL3608798 IC50 6.0 nM
COc1ccc2[nH]nc(Nc3cccc(Cl)c3)c2c1 CHEMBL3608800 IC50 8.0 nM
C[C@H]1[C@H](c2ccc(F)cc2)OC(=O)N1c1cccc(C#N)c1 CHEMBL4070383 IC50 8.7 nM
Clc1cccc(Nc2ncnc3ccccc23)c1 CHEMBL329672 IC50 11.0 nM
COc1ccc(O)c(C(=O)Nc2cccc(Cl)c2)c1 CHEMBL3608697 IC50 15.0 nM
Clc1cccc(Nc2cccc3ccccc23)c1 CHEMBL3608700 IC50 17.0 nM
Clc1cccc(Nc2ccnc3ccccc23)c1 CHEMBL3608699 IC50 18.0 nM
COc1ccc(OC)c(N2CC(c3ccc(F)cc3)OC2=O)c1 CHEMBL4090490 IC50 18.0 nM
Clc1cccc(Nc2n[nH]c3ccc(Br)cc23)c1 CHEMBL3608797 IC50 21.0 nM
Nc1ccccc1C(=O)Nc1cccc(Cl)c1 CHEMBL2263368 IC50 29.0 nM
Nc1ccc(Cl)cc1C(=O)Nc1cccc(Cl)c1 CHEMBL3608696 IC50 34.0 nM
Clc1cccc(Nc2ncnc3ccsc23)c1 CHEMBL3608702 IC50 50.0 nM
O=C1OC(c2ccc(F)cc2)CN1c1cccc(Cl)c1 CHEMBL4104260 IC50 55.0 nM
Fc1ccc2[nH]nc(Nc3cccc(Cl)c3)c2c1 CHEMBL3608795 IC50 58.0 nM
Fc1cccc(Nc2n[nH]c3ccccc23)c1 CHEMBL3608794 IC50 59.0 nM
N#Cc1cccc(N2C[C@H](c3ccc(F)cc3)OC2=O)c1 CHEMBL4066595 IC50 60.0 nM
Nc1ccc(F)cc1C(=O)Nc1cccc(Cl)c1 CHEMBL3608695 IC50 67.0 nM
Clc1cccc(Nc2n[nH]c3ccccc23)c1 CHEMBL3608793 IC50 84.0 nM
O=C1OC(c2ccc(F)cc2)CN1Cc1ccc(Cl)cc1Cl CHEMBL4069465 IC50 150.0 nM
Nc1ccccc1C(=O)Nc1ccc(F)c(Cl)c1 CHEMBL2263369 IC50 155.0 nM
N#Cc1cccc(N2CC(c3ccc(F)cc3)OC2=O)c1 CHEMBL4087912 IC50 170.0 nM
O=C1OC(c2ccc(F)cc2)CN1c1cccc(F)c1 CHEMBL4080025 IC50 170.0 nM
Clc1cccc(NC2CCc3ccccc32)c1 CHEMBL3608704 IC50 173.0 nM
O=C(Nc1cccc(Cl)c1)c1ccccc1O CHEMBL460481 IC50 174.0 nM
O=C1OC(c2ccc(F)cc2)CN1c1ccccc1 CHEMBL4085437 IC50 190.0 nM
Nc1ccccc1C(=O)Nc1cc(Cl)cc(Cl)c1 CHEMBL3608803 IC50 245.0 nM
FC(F)(F)c1ccc2[nH]nc(Nc3cccc(Cl)c3)c2c1 CHEMBL3608799 IC50 254.0 nM
Clc1cccc(Nc2ncnc3sccc23)c1 CHEMBL3608703 IC50 260.0 nM
Clc1cccc(Nc2nccc3occc23)c1 CHEMBL3608701 IC50 371.0 nM
Nc1ccccc1C(=O)Nc1cccc(F)c1 CHEMBL3608693 IC50 516.0 nM
CC(C)c1cccc(NC(=O)c2ccccc2N)c1 CHEMBL3608694 IC50 843.0 nM
CCOc1ccc(O)c(C(=O)Nc2cccc(Cl)c2)c1 CHEMBL3608698 IC50 925.0 nM