COc1cc(O[C@H]2C[C@H](OC)C2)nc(-c2ccc3c(c2)CC[C@H](CCC(=O)O)O3)c1F CHEMBL3952043 EC50 5.0 nM
C#Cc1cc(Oc2cccnc2)cc(N2Cc3ccccc3S2(=O)=O)c1 CHEMBL5286838 EC50 5.3 nM
Cc1cnc(Oc2cc(Cl)c(F)c(-c3ccc4c(c3)CC[C@H](CCC(=O)O)O4)c2)s1 CHEMBL3972870 EC50 5.6 nM
O=C(O)CCc1ccc(OCc2cccc(SCC3CC3)n2)c(Cl)c1 CHEMBL4637969 EC50 6.0 nM
COc1ccc(F)c(-c2ncc(COc3ccc([C@@H](CC(=O)O)C4CC4)cc3)nc2OCCC(F)(F)F)c1 CHEMBL4646784 EC50 6.0 nM
COc1cc(OC2CCC2)nc(-c2ccc3c(c2)CC[C@H](CCC(=O)O)O3)c1F CHEMBL3960738 EC50 6.2 nM
COc1cc(OC2CCC2)nc(-c2ccc3c(c2)CC[C@H]([C@@H]2C[C@H]2C(=O)O)O3)c1F CHEMBL3898962 EC50 7.8 nM
COc1cc(OC2CCC2)cc(-c2ccc3c(c2)CC[C@H]([C@@H]2C[C@H]2C(=O)O)O3)c1F CHEMBL3970166 EC50 8.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC4CCC4)cc(Cl)c3F)ccc2O1 CHEMBL3909773 EC50 8.3 nM
COc1cc(OC2CCC2)cc(-c2ccc3c(c2)CC[C@H](CCC(=O)O)O3)c1F CHEMBL3940429 EC50 9.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC4CCC4)ccc3F)ccc2O1 CHEMBL3970238 EC50 10.0 nM
COc1cc(OC(F)(F)F)cc(-c2ccc3c(c2)CC[C@H](CCC(=O)O)O3)c1F CHEMBL3890089 EC50 11.0 nM
COc1cc(Oc2ncc(C)s2)cc(-c2ccc3c(c2)CC[C@H](CCC(=O)O)O3)c1F CHEMBL3943315 EC50 13.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC4CCC4)cc(F)c3F)ccc2O1 CHEMBL3947070 EC50 13.0 nM
O=C(O)CCc1cc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2o1 CHEMBL3896657 EC50 16.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3ccc4c(c3)CC[C@H]([C@@H]3C[C@H]3C(=O)O)O4)c2)C1 CHEMBL3959068 EC50 17.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC(F)(F)F)cc(Cl)c3F)ccc2O1 CHEMBL3959144 EC50 17.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2O1 CHEMBL3960231 EC50 17.0 nM
O=C(O)CCCOc1c(F)cc(-c2cc(OC(F)(F)F)ccc2F)cc1F CHEMBL3973101 EC50 20.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3nc(OC4CCC4)ccc3F)ccc2O1 CHEMBL3946820 EC50 21.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3ccc4c(c3)CC[C@H](CCC(=O)O)O4)n2)C1 CHEMBL3980898 EC50 24.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(Cl)c(F)c3)nsc2C(F)(F)F)c(F)c1 CHEMBL4171724 EC50 25.0 nM
O=C(O)CCc1ccc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c(Br)c1 CHEMBL4162566 EC50 31.0 nM
COc1cc(OC2CC2)cc(-c2ccc3c(c2)CC[C@H](CCc2nnn[nH]2)O3)c1F CHEMBL3932664 EC50 32.0 nM
O=C(O)[C@@H]1C[C@H]1[C@H]1CCc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2O1 CHEMBL3971308 EC50 33.0 nM
CCc1ccc(-c2nsc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4161536 EC50 34.0 nM
O=S1(=O)c2ccccc2CN1c1cc(Cl)cc(Oc2ccccn2)c1 CHEMBL3910333 pEC50 38.9 nM
Cc1cc(COc2ccc(CCC(=O)O)cc2C)cc(Oc2ccccc2)c1 CHEMBL4103243 pEC50 39.81 nM
CCc1ccc(-n2ccc(C(F)(F)F)c2COc2ccc(CCC(=O)O)c(F)c2F)cc1 CHEMBL4212409 EC50 40.0 nM
O=C(O)CC[C@@H]1CCc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2O1 CHEMBL3941726 EC50 42.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(Cl)cc3F)nsc2C(F)(F)F)c(F)c1 CHEMBL4165366 EC50 42.0 nM
COc1cc(O[C@H]2C[C@H](OC)C2)cc(-c2ccc3c(c2)CC[C@H](CCc2nnn[nH]2)O3)c1F CHEMBL3907996 EC50 43.0 nM
OCCCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c(F)c1 CHEMBL4209308 EC50 43.0 nM
Cc1ccc(-c2ccc(F)cc2COc2ccc(CCC(=O)O)cc2)cc1 CHEMBL2058533 pEC50 43.65 nM
O=C(O)CCC1CCC2(CCN(c3cc(OC4CCC4)ccc3Cl)CC2)C1 CHEMBL4639009 EC50 44.8 nM
Cc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4205429 EC50 50.0 nM
O=C(O)CCCc1ccc(OCC2=C(c3ccc(C4CC4)cc3)CCCC2)cc1 CHEMBL4641038 EC50 50.0 nM
O=C(O)CCCc1ccc(OCC2=C(c3ccc4c(c3)CCCC4)CCCC2)cc1 CHEMBL5285896 EC50 50.0 nM
Cc1ccc(C2=C(COc3ccc(CCCC(=O)O)cc3)CCCC2)cc1 CHEMBL5272316 EC50 50.0 nM
Cc1ccc(Br)c(COc2ccc(CCC(=O)O)cc2C)c1 CHEMBL4084333 pEC50 50.12 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c(F)c1 CHEMBL4159180 EC50 51.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(C(F)(F)F)cc3)nsc2C(F)(F)F)c(F)c1 CHEMBL4172136 EC50 51.0 nM
COc1cc(O[C@H]2C[C@H](OC)C2)cc(-c2ccc3c(c2)CC[C@H]([C@@H]2C[C@H]2C(=O)O)O3)c1F CHEMBL3890035 EC50 55.0 nM
CCc1ccc(-c2snc(Cl)c2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4169436 EC50 56.0 nM
O=C(O)CCCOc1ccc(-c2cc(OC(F)(F)F)ccc2Cl)cc1 CHEMBL3968947 EC50 57.0 nM
CCc1ccc(-c2noc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4086174 EC50 57.0 nM
O=C(O)CCCOc1ccc(-c2cc(Oc3cccc(F)c3)ccc2F)cc1 CHEMBL3953203 EC50 60.0 nM
Cc1cc(C)cc(COc2ccc(CCC(=O)O)cc2C)c1 CHEMBL4062640 EC50 60.0 nM
Cc1cc(COc2ccc(CCC(=O)O)cc2C)cc(OC(C)C)c1 CHEMBL4100773 EC50 60.0 nM
OCCCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Br)cc2)c(F)c1 CHEMBL4646553 EC50 61.0 nM
[2H]C([2H])(Cc1ccc(OCc2cc(F)ccc2-c2ccc(C)cc2)cc1)C(=O)O CHEMBL4218325 EC50 63.1 nM
O=C(O)CCCOc1ccc(-c2cc(OC3CC3)ccc2F)cc1 CHEMBL3944507 EC50 66.0 nM
O=C(O)CC1CCC2(CC1)CCN(c1cc(OC(F)(F)F)ccc1Cl)CC2 CHEMBL3919973 EC50 66.0 nM
Cc1cc(OC2CCC2)cc(-c2ccc3oc(CCC(=O)O)cc3c2)c1 CHEMBL3920591 EC50 68.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccccc3)noc2C(F)(F)F)c(F)c1 CHEMBL4080995 EC50 69.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c(F)c1 CHEMBL4208325 EC50 69.0 nM
COc1cc(F)c(F)c(-c2cc(F)c(OCCCC(=O)O)c(F)c2)c1 CHEMBL4238809 EC50 69.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(F)cc3Cl)noc2C(F)(F)F)c(F)c1 CHEMBL4060663 EC50 71.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(Cl)cc3)noc2C(F)(F)F)c(F)c1 CHEMBL4061699 EC50 71.0 nM
Cc1c(CCC(=O)O)cc(F)c(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c1F CHEMBL4164509 EC50 71.0 nM
COc1cc(N2CCC(Oc3ccc(N4N=C(C(F)(F)F)[C@@H](C)C4CC(=O)O)cc3)C(C)C2)c(Cl)cn1 CHEMBL4642324 EC50 71.0 nM
COc1ccc(-c2nsc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4169851 EC50 75.0 nM
O=C(O)CCC1Cc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2O1 CHEMBL3939004 EC50 77.0 nM
COc1nn(-c2ccc(C)cc2)c2cc(-c3ccc([C@H]4C[C@@H]4C(=O)O)cc3)cc(F)c12 CHEMBL4096579 EC50 78.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC4CCC4)cnc3F)ccc2O1 CHEMBL3900705 EC50 79.0 nM
Cc1ccc(S(=O)(=O)NC2c3ccccc3Oc3ccccc32)cc1 CHEMBL3311302 pIC50 79.43 nM
Cc1c(CCC(=O)O)ccc(OCc2scnc2-c2ccc(Cl)cc2)c1C CHEMBL4062742 EC50 81.0 nM
CC(Cc1cc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2o1)C(=O)O CHEMBL3921062 EC50 83.0 nM
Fc1ccc(OC2CCC2)cc1-c1ccc2c(c1)CC[C@H](CCc1nnn[nH]1)O2 CHEMBL3986721 EC50 84.0 nM
O=C(O)CCc1ccc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c(F)c1F CHEMBL4167097 EC50 86.0 nM
O=C(O)CCCOc1ccc(-c2cc(Oc3cccnc3)ccc2Cl)cc1 CHEMBL3938783 EC50 88.0 nM
Cc1c(CCC(=O)O)ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c1C CHEMBL4208442 EC50 88.0 nM
O=C(O)CCc1ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c(F)c1F CHEMBL4203559 EC50 91.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3cc(F)c(OCCCC(=O)O)c(F)c3)c2)C1 CHEMBL4246396 EC50 93.0 nM
Cc1cc(-c2cc(OC(F)(F)F)ccc2Cl)cc(C)c1OCCCC(=O)O CHEMBL3909872 EC50 94.0 nM
Cc1c(CCC(=O)O)ccc(OCc2c(C(F)(F)F)nsc2-c2ccc(Cl)cc2)c1C CHEMBL4177287 EC50 94.0 nM
O=C(O)CCc1cc2cc(-c3cc(C(=O)C4CC4)ccc3F)ccc2o1 CHEMBL3927879 EC50 97.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(OC(F)(F)F)cc3)nsc2C(F)(F)F)c(F)c1 CHEMBL4161929 EC50 99.0 nM
O=C(O)CCCOc1ccc(-c2cc(Oc3ccccc3)ccc2F)cc1 CHEMBL3985509 EC50 100.0 nM
O=C(O)CCc1ccc(OCc2ccccc2SC(F)(F)F)c(Cl)c1 CHEMBL4086893 pEC50 100.0 nM
CCc1ccc(-n2cccc2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4076902 EC50 100.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccccc2)c(F)c1 CHEMBL4217143 EC50 100.0 nM
O=C(O)CCc1cc2cc(-c3cc(OC(F)(F)F)ccc3Cl)ccc2o1 CHEMBL3899885 EC50 102.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c(F)c1F CHEMBL4172392 EC50 104.0 nM
Cc1snc(-c2ccc(Cl)cc2)c1COc1ccc(CCC(=O)O)c(C)c1C CHEMBL4166208 EC50 106.0 nM
O=C(O)CCc1ccc(OCc2cc(F)ccc2-c2ccccc2)cc1 CHEMBL2058532 pEC50 109.65 nM
Cc1ccc(-c2noc(C(F)(F)F)c2COc2c(F)cc(CC(C)C(=O)O)cc2F)cc1 CHEMBL4067368 EC50 110.0 nM
CCc1cc2cc(C(F)(F)F)cc(COc3ccc(CCC(=O)O)c(C)c3C)c2o1 CHEMBL4638249 EC50 110.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Br)cc2)c(F)c1 CHEMBL4213709 EC50 112.0 nM
CCc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4204928 EC50 117.0 nM
Cc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)c(F)c1 CHEMBL4204946 EC50 118.0 nM
Cc1ccc(-c2noc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4104082 EC50 120.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(Br)cc3)noc2C(F)(F)F)c(F)c1 CHEMBL4088889 EC50 120.0 nM
CCc1ccc(-c2nsc(C(F)(F)F)c2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4165803 EC50 120.0 nM
CCOc1ccc(Cl)c(-c2ccc(OCCCC(=O)O)cc2)c1 CHEMBL3924759 EC50 121.0 nM
Cc1cc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c(F)cc1CCC(=O)O CHEMBL4170501 EC50 121.0 nM
O=S1(=O)c2ccccc2CN1c1cc(F)cc(Oc2ccccn2)c1 CHEMBL3941880 pEC50 123.03 nM
OCCCc1c(F)cc(OCc2c(-c3ccc(Cl)cc3)csc2C(F)(F)F)cc1F CHEMBL5275980 EC50 125.0 nM
[2H]C([2H])(Cc1ccc(OCc2cc(F)ccc2-c2ccccc2)cc1)C(=O)O CHEMBL4207911 EC50 126.8 nM
O=C(O)[C@H]1C[C@@H]1[C@H]1CCc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2O1 CHEMBL3950444 EC50 130.0 nM
COc1cc(OC(F)(F)F)cc(-c2ccc3c(c2)CC[C@H](CCc2nnn[nH]2)O3)c1F CHEMBL3978465 EC50 130.0 nM
O=C(O)CC1CCC2(CC1)CCN(c1cc(OC(F)(F)F)ccc1F)CC2 CHEMBL3891920 EC50 130.0 nM
CCCc1onc(-c2ccc(Cl)cc2)c1COc1ccc(CCC(=O)O)c(C)c1C CHEMBL4074388 EC50 130.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccccc3)nsc2C(F)(F)F)c(F)c1 CHEMBL4168786 EC50 132.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(F)cc2)c(F)c1 CHEMBL4206168 EC50 134.0 nM
O=C(O)CCc1ccc(OCc2c(-c3ccc(Cl)cc3)noc2C(F)(F)F)c(F)c1F CHEMBL4073078 EC50 140.0 nM
Cc1c(CCC(=O)O)ccc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c1C CHEMBL3754160 EC50 141.0 nM
CCc1ccc(-c2cscc2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4092882 EC50 142.0 nM
Cc1c(CCC(=O)O)ccc(OCc2cccn2-c2ccc(Cl)cc2)c1C CHEMBL4061340 EC50 145.0 nM
Cc1cc(-c2cc(OC(F)(F)F)ccc2F)cc(C)c1OCCCC(=O)O CHEMBL3985939 EC50 149.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)c(F)c1 CHEMBL4099026 EC50 150.0 nM
O=C(O)CCc1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)cc1 CHEMBL4083499 EC50 150.0 nM
Cc1ccc(Nc2nc(N)nc(COc3ccc4c(C)cc(=O)oc4c3)n2)cc1Cl CHEMBL5290885 EC50 150.0 nM
Cc1ccc(Nc2nc(N)nc(COc3cc(Cl)cc(N4CCCC4=O)c3)n2)cc1Cl CHEMBL5266881 EC50 150.0 nM
O=C(O)CCc1cc2cc(-c3cccc(OC4CCC4)c3)ccc2o1 CHEMBL3968537 EC50 153.0 nM
CCc1cc(CCC(=O)O)ccc1OCc1c(-c2ccc(Cl)cc2)nsc1C(F)(F)F CHEMBL4166012 EC50 156.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(F)cc2F)c(F)c1 CHEMBL4203544 EC50 156.0 nM
Cc1ccc(OC(C)C)c(COc2ccc(CCC(=O)O)cc2C)c1 CHEMBL4074009 pEC50 158.49 nM
CCc1ccc(-c2ccsc2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4103081 EC50 160.0 nM
Cc1c(CCC(=O)O)ccc(OCc2c(-c3ccc(Cl)cc3)noc2C(F)(F)F)c1C CHEMBL4099943 EC50 160.0 nM
O=C(O)CCc1ccc(OCc2c(Br)ccn2-c2ccc(Cl)cc2)c(F)c1F CHEMBL4212281 EC50 161.0 nM
OCCCc1ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c(F)c1F CHEMBL4205879 EC50 162.0 nM
Cc1c(CCC(=O)O)ccc(OCc2cccn2-c2ccc(Br)cc2)c1C CHEMBL4217252 EC50 164.0 nM
O=C(O)CCCOc1ccc(-c2cccc(Oc3ccccc3)c2)cc1 CHEMBL3897776 EC50 170.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3ccc4c(c3)CC[C@H](CCc3nnn[nH]3)O4)c2)C1 CHEMBL3916986 EC50 170.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(C4CC4)cc3)noc2C(F)(F)F)c(F)c1 CHEMBL4096332 EC50 170.0 nM
O=C(O)CCc1c(F)c(F)c(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)c(F)c1F CHEMBL4176642 EC50 173.0 nM
Cc1c(CCC(=O)O)ccc(OCc2c(Cl)ccn2-c2ccc(Cl)cc2)c1C CHEMBL4205035 EC50 173.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(F)c(F)c2)c(F)c1 CHEMBL4217161 EC50 175.0 nM
Cc1ccc(-c2ccccc2COc2ccc(CCC(=O)O)cc2)cc1 CHEMBL2058520 pEC50 177.83 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2F)c(F)c1 CHEMBL4209823 EC50 179.0 nM
Cc1ccc(-c2nsc(C(F)(F)F)c2COc2c(F)cc(CC(C)C(=O)O)cc2F)c(F)c1 CHEMBL4647832 EC50 179.0 nM
O=S1(=O)c2ccccc2CN1c1cc(F)cc(Oc2cccnc2)c1 CHEMBL3908362 pEC50 181.97 nM
Cc1ccc(Oc2cccc(-c3ccc(OCCCC(=O)O)cc3)c2)cc1 CHEMBL3916564 EC50 182.0 nM
COc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4212717 EC50 184.0 nM
Cc1cc(-c2cc(OC(F)(F)F)ccc2Cl)ccc1OCCCC(=O)O CHEMBL3892019 EC50 185.0 nM
O=C(O)CCCOc1ccc(-c2cc(OC(F)(F)F)ccc2Cl)c(F)c1 CHEMBL3942922 EC50 186.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3cc(F)c(OCCCCC(=O)O)c(F)c3)c2)C1 CHEMBL4240607 EC50 186.0 nM
O=C(O)CCc1cc2cc(-c3cc(Cl)cc(OC4CCC4)c3)ccc2o1 CHEMBL3947787 EC50 188.0 nM
Cc1ccc(Cl)c(COc2ccc(CCC(=O)O)cc2C)c1 CHEMBL4071290 EC50 188.0 nM
O=C(O)CC1CCC2(CC1)CCN(c1cc(Cl)cc(Cl)c1)CC2 CHEMBL3893026 EC50 190.0 nM
CCc1ccc(-c2sncc2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4095819 EC50 190.0 nM
O=C(O)CCc1cc(F)c(OCc2c(-c3ccc(C(F)(F)F)cc3)noc2C(F)(F)F)c(F)c1 CHEMBL4078286 EC50 190.0 nM
COc1ccc(-c2ccccc2COc2ccc(CCC(=O)O)cc2)cc1 CHEMBL2058525 pEC50 190.55 nM
[2H]C([2H])(Cc1ccc(OCc2ccccc2-c2ccc(C)cc2)cc1)C(=O)O CHEMBL4210970 EC50 195.6 nM
COc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cn1 CHEMBL4214224 EC50 197.0 nM
O=C(O)CCCOc1ccc(-c2cc(Oc3cccc(F)c3)ccc2Cl)cc1 CHEMBL3961950 EC50 198.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1ccccc1SC(F)(F)F CHEMBL4091228 pEC50 199.53 nM
N#Cc1ccc(OC(F)(F)F)cc1N1CCC2(CCC(CC(=O)O)CC2)CC1 CHEMBL3973034 EC50 200.0 nM
CC(C)Nc1ccccc1-c1cc(F)c(OCCCC(=O)O)c(F)c1 CHEMBL4246850 EC50 200.0 nM
O=C(O)CCCOc1ccc(-c2cc(-[n+]3ccsc3)ccc2Cl)cc1 CHEMBL3972973 EC50 204.0 nM
O=S1(=O)c2ccccc2CN1c1cccc(Oc2ccccc2)c1 CHEMBL3904654 pEC50 208.93 nM
Cc1c(CCC(=O)O)ccc(OCc2csnc2-c2ccc(Cl)cc2)c1C CHEMBL4077787 EC50 215.0 nM
Cc1c(CCC(=O)O)ccc(OCc2ccccc2-c2ccc(Cl)cc2)c1C CHEMBL4083233 EC50 220.0 nM
CO[C@H]1C[C@H](Oc2cc3c(c(-c4cc(F)c(OCCCC(=O)O)c(F)c4)c2)OCO3)C1 CHEMBL4250664 EC50 220.0 nM
O=C(O)[C@H]1C[C@@H]1CCC12CCC(c3cccc(Oc4ccccc4)c3)(CC1)O2 CHEMBL4642294 EC50 220.0 nM
O=C(O)CC[C@H]1CCc2cc(-c3cc(OC4CCC4)ncc3F)ccc2O1 CHEMBL3971857 EC50 230.0 nM
CSc1ccc(-c2ccccc2COc2ccc(CCC(=O)O)cc2)cc1 CHEMBL2058528 pEC50 234.42 nM
O=S1(=O)c2ccccc2CN1c1cc(F)cc(Oc2ccccc2)c1 CHEMBL3945213 pEC50 234.42 nM
Cc1cc(CCC(=O)O)ccc1OCc1ccccc1Br CHEMBL4064298 EC50 236.0 nM
O=C(O)CCc1ccc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)cc1C(F)(F)F CHEMBL4173940 EC50 236.0 nM
O=C(O)CCc1ccc(OCc2cc(Cl)ccc2-c2ccccc2)cc1 CHEMBL2058529 pEC50 239.88 nM
COc1nn(-c2ccccn2)c2cc(-c3ccc(CCC(=O)O)cc3)ccc12 CHEMBL4087992 EC50 250.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1ccccc1OC(C)C CHEMBL4093589 pEC50 251.19 nM
Cc1cccc(COc2ccc(CCC(=O)O)cc2C)c1 CHEMBL4092090 pEC50 251.19 nM
Cc1cc(OCCCC(=O)O)ccc1-c1cc(OC(F)(F)F)ccc1Cl CHEMBL3961009 EC50 254.0 nM
Cc1nn(-c2ccccn2)c2cc(-c3ccc(CCCC(=O)O)cc3)ccc12 CHEMBL4076190 EC50 260.0 nM
Cc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1F CHEMBL4206369 EC50 262.0 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(CCC(=O)O)c(C)c1C CHEMBL4093383 EC50 270.0 nM
O=C(O)CCC12CCC(OCc3cc(F)cc(Oc4ccccc4)c3)(CC1)CC2 CHEMBL4641735 EC50 270.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1c(C(F)(F)F)ccn1-c1ccc(F)cc1 CHEMBL4203774 EC50 280.0 nM
Cc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cn1 CHEMBL4211144 EC50 289.0 nM
CCOc1ccc(F)c(-c2ccc(OCCCC(=O)O)cc2)c1 CHEMBL3896714 EC50 290.0 nM
CC(Cc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c(F)c1)C(=O)O CHEMBL4214698 EC50 290.0 nM
O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(Br)cc2)cc1 CHEMBL2058523 pEC50 295.12 nM
COc1ccc(C(F)(F)F)cc1COc1ccc(CCC(=O)O)cc1C CHEMBL4065397 EC50 299.0 nM
CS(=O)(=O)CCCOCc1cccc(C#Cc2ccc(CCC(=O)O)c(F)c2)c1 CHEMBL2386371 EC50 300.0 nM
CS(=O)(=O)CCCOCc1ccccc1C#Cc1ccc(CCC(=O)O)c(F)c1 CHEMBL2386370 EC50 300.0 nM
CS(=O)(=O)CCOCc1cccc(C#Cc2ccc(CCC(=O)O)c(F)c2)c1 CHEMBL2386369 EC50 300.0 nM
CS(=O)(=O)CCOCc1ccccc1C#Cc1ccc(CCC(=O)O)c(F)c1 CHEMBL2386368 EC50 300.0 nM
O=C(O)C1CCN(c2ccc(-c3cc(OC(F)(F)F)ccc3F)cc2)CC1 CHEMBL3933619 EC50 300.0 nM
Cc1c(CCC(=O)O)ccc(OCc2ccccc2SC(F)(F)F)c1C CHEMBL4098969 EC50 304.0 nM
Cc1cc(-c2cc(OC(F)(F)F)ccc2F)ccc1OCCCC(=O)O CHEMBL3900990 EC50 308.0 nM
O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(Cl)cc2)cc1 CHEMBL2058522 pEC50 309.03 nM
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O CHEMBL267476 pEC50 316.23 nM
Cc1cc(C)c(NS(=O)(=O)c2ccc3c(c2)OCCO3)c(C)c1 CHEMBL3311325 pEC50 316.23 nM
C=CCc1cc(C)c(NS(=O)(=O)c2ccc(OC)cc2)c(C)c1 CHEMBL3311327 pEC50 316.23 nM
Fc1ccc(OC(F)(F)F)cc1-c1ccc2c(c1)CC[C@H](CCc1nnn[nH]1)O2 CHEMBL3979448 EC50 330.0 nM
OCCC1CCC2(CC1)CCN(c1cc(OC(F)(F)F)ccc1Cl)CC2 CHEMBL3967504 EC50 330.0 nM
CCc1ccc(-c2nsc(C(F)(F)C(F)(F)F)c2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4162353 EC50 332.0 nM
N#Cc1ccc(-c2nsc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1 CHEMBL4173280 EC50 332.0 nM
Cc1c(CCC(=O)O)ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(F)cc2)c1C CHEMBL4211967 EC50 346.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3cc(F)c(SCCCC(=O)O)c(F)c3)c2)C1 CHEMBL4243863 EC50 347.0 nM
Cc1noc(-c2ccc(Cl)cc2)c1COc1ccc(CCC(=O)O)c(C)c1C CHEMBL4065769 EC50 350.0 nM
N#Cc1cc(SC(F)(F)F)cc(N2CCC3(CCC(CC(=O)O)CC3)CC2)c1 CHEMBL3953289 EC50 360.0 nM
Cc1ccc(-n2nc(C)c3ccc(-c4ccc([C@H]5C[C@@H]5C(=O)O)cc4)cc32)cc1 CHEMBL4078553 EC50 360.0 nM
Cc1cc(=O)oc2cc(OCc3nc(N)nc(Nc4ccc(Cl)c(Cl)c4)n3)ccc12 CHEMBL5278642 EC50 360.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1cccc(Cl)c1 CHEMBL4085843 EC50 362.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)c(F)c2)c(F)c1 CHEMBL4218078 EC50 368.0 nM
O=C(O)CCc1ccc(OCc2ccccc2-c2ccccc2)cc1 CHEMBL1688455 pEC50 371.54 nM
[2H]C([2H])(Cc1ccc(OCc2ccccc2-c2ccccc2)cc1)C(=O)O CHEMBL4213909 EC50 396.2 nM
CCCc1ccc(S(=O)(=O)Nc2c(C)cc(C)cc2C)cc1 CHEMBL3311319 pEC50 398.11 nM
COc1ccc(S(=O)(=O)Nc2c(C)cc(OC)cc2C)cc1 CHEMBL3311198 pEC50 398.11 nM
CCc1onc(-c2ccc(Cl)cc2)c1COc1ccc(CCC(=O)O)c(C)c1C CHEMBL4101135 EC50 400.0 nM
Cc1cc(OCc2c(-c3ccc(Cl)cc3)noc2C(F)(F)F)c(F)cc1CCC(=O)O CHEMBL4070355 EC50 410.0 nM
O=C(O)CC1CCC2(CC1)CCN(c1cc(F)cc(Cl)c1F)CC2 CHEMBL3901994 EC50 420.0 nM
Cc1ccc(Oc2cc(F)cc(N3Cc4ccccc4S3(=O)=O)c2)cc1 CHEMBL3932897 pEC50 436.52 nM
CC1CC(CC(=O)O)CCC12CCN(c1cc(OC(F)(F)F)ccc1Cl)CC2 CHEMBL3940359 EC50 440.0 nM
O=C(O)CCc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2cccc(F)c2)c(F)c1 CHEMBL4217669 EC50 448.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3ccc4c(c3)CC[C@H](CCC(=O)O)O4)c2)C1 CHEMBL4242595 EC50 463.0 nM
O=C(O)CCc1ccc(-c2cc(F)c3cnn(-c4ccccn4)c3c2)cc1 CHEMBL4089919 EC50 470.0 nM
COc1nn(-c2ccccn2)c2cc(-c3ccc([C@H]4C[C@@H]4C(=O)O)cc3)ccc12 CHEMBL4097537 EC50 470.0 nM
O=C(O)CCCOc1ccc(-c2noc3ccccc23)c(Cl)c1Cl CHEMBL3984072 EC50 474.0 nM
O=C(O)CCc1ccc(OCc2cccc(Br)c2)cc1 CHEMBL1773254 pEC50 478.63 nM
COc1ccc(S(=O)(=O)Nc2c(C)cc(C)cc2C)cc1 CHEMBL3311308 pEC50 489.78 nM
COc1cccc(Oc2cccc(-c3ccc(OCCCC(=O)O)cc3)c2)c1 CHEMBL3934450 EC50 498.0 nM
COc1ccc(S(=O)(=O)Nc2c(C)cc(Cl)cc2C)cc1 CHEMBL3311197 pEC50 501.19 nM
Cc1cc(CCC(=O)O)ccc1OCc1ccccc1C(F)(F)F CHEMBL4072885 pEC50 501.19 nM
Cc1cc(CCC(=O)O)ccc1OCc1cccc(Oc2ccccc2)c1 CHEMBL4097919 pEC50 501.19 nM
COc1nn(-c2ccccn2)c2cc(-c3ccc([C@H]4C[C@@H]4C(=O)O)cc3)cc(F)c12 CHEMBL4080998 EC50 510.0 nM
Cc1ccc(-c2ccc(Cl)cc2COc2ccc(CCC(=O)O)cc2)cc1 CHEMBL2058531 pEC50 512.86 nM
Cc1ccc(-n2nc(C)c3c(F)cc(-c4ccc([C@H]5C[C@@H]5C(=O)O)cc4)cc32)cc1 CHEMBL4105241 EC50 520.0 nM
CCc1ccc(-n2nccc2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4073815 EC50 520.0 nM
Cc1c(CCCO)ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(Cl)cc2)c1C CHEMBL4210752 EC50 533.0 nM
O=C(O)CCc1cc2cc(-c3cccc(OC(F)(F)F)c3)ccc2o1 CHEMBL3952316 EC50 544.0 nM
O=C(O)CCCOc1ccc(-c2ccccc2Oc2ccccc2)cc1 CHEMBL3940493 EC50 546.0 nM
CC(Cc1cc(F)c(OCc2c(C(F)(F)F)ccn2-c2ccc(F)cc2)c(F)c1)C(=O)O CHEMBL4215446 EC50 547.0 nM
CCc1ccc(Nc2nc(N)nc(COc3ccc4c(C)cc(=O)oc4c3)n2)cc1Cl CHEMBL5273250 EC50 560.0 nM
O=C(O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1 CHEMBL1688458 pEC50 562.34 nM
Cc1nn(C)c2nc(NNC(=O)Nc3cc(Cl)nc(Cl)c3)cc(C(C)C)c12 CHEMBL1368758 EC50 585.29 nM
O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(F)cc2)cc1 CHEMBL2058521 pEC50 588.84 nM
Cc1ccc(Nc2nc(N)nc(COc3cccc(N4CCCC4=O)c3)n2)cc1Cl CHEMBL5278718 EC50 590.0 nM
Cc1nn(-c2ccccn2)c2cc(-c3ccc(CCC(=O)O)cc3F)ccc12 CHEMBL4075162 EC50 600.0 nM
Cc1cc(Nc2nc(N)nc(COc3ccc4c(C)cc(=O)oc4c3)n2)ccc1Cl CHEMBL5268389 EC50 600.0 nM
COc1cc(OCc2nc(N)nc(Nc3ccc(C)c(Cl)c3)n2)cc(N2CCCC2=O)c1 CHEMBL5287642 EC50 600.0 nM
Cc1cc(OCc2nc(N)nc(Nc3ccc(C)c(Cl)c3)n2)cc(N2CCCC2=O)c1 CHEMBL5268316 EC50 600.0 nM
Cc1c(CCC(=O)O)ccc(OCc2ccnn2-c2ccc(Cl)cc2)c1C CHEMBL4062462 EC50 610.0 nM
O=C(O)CCc1ccc(OCc2ccccc2SC(F)(F)F)cc1 CHEMBL4105013 pEC50 630.96 nM
Cc1cc(CCC(=O)O)cc(C)c1OCc1ccccc1SC(F)(F)F CHEMBL4070298 pEC50 630.96 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3cc(F)c(OCCCCCC(=O)O)c(F)c3)c2)C1 CHEMBL4250132 EC50 638.0 nM
Cc1nn(-c2ccccn2)c2cc(-c3ccc(CCC(=O)O)cc3)ccc12 CHEMBL4077507 EC50 640.0 nM
Cc1ccc(Nc2nc(N)nc(COc3cc(N4CCCC4=O)cc(C(C)(C)C)c3)n2)cc1Cl CHEMBL5266170 EC50 640.0 nM
CCc1ccc(-c2nsc(CC)c2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4174122 EC50 680.0 nM
Cc1nn(-c2ccccn2)c2cc(-c3ccc([C@H]4C[C@@H]4C(=O)O)cc3)ccc12 CHEMBL4060171 EC50 690.0 nM
O=C(O)C1CCC(C2CCN(c3cc(OC(F)(F)F)ccc3F)CC2)CC1 CHEMBL3906716 EC50 700.0 nM
Cc1nn(-c2ccccn2)c2cc(-c3ccc(CCC(=O)O)cc3Cl)ccc12 CHEMBL4101071 EC50 710.0 nM
COc1cc(CCC(=O)O)ccc1-c1ccc2c(C)nn(-c3ccccn3)c2c1 CHEMBL4070273 EC50 720.0 nM
Cc1cc(OCc2ccccc2SC(F)(F)F)ccc1CCC(=O)O CHEMBL4061630 EC50 722.0 nM
Cc1ccc(-n2nc(C)c3cnc(-c4ccc([C@H]5C[C@@H]5C(=O)O)cc4F)cc32)nc1 CHEMBL4070359 EC50 740.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1ccccc1 CHEMBL4083325 EC50 750.0 nM
CCc1nn(-c2ccccn2)c2cc(-c3ccc(CCC(=O)O)cc3)ccc12 CHEMBL4076004 EC50 760.0 nM
N#CCc1ccccc1C#Cc1ccc(CCC(=O)O)cc1 CHEMBL2315528 pEC50 776.25 nM
COc1cc(S(=O)(=O)Nc2c(C)cc(C)cc2C)ccc1Cl CHEMBL1581959 pEC50 794.33 nM
CC(CC(=O)O)c1cc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2o1 CHEMBL3914253 EC50 819.0 nM
O=C(O)CCc1ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(F)cc2)cc1C(F)(F)F CHEMBL4216937 EC50 834.0 nM
CO[C@H]1C[C@H](Oc2cc(F)c(F)c(-c3cc(C)c(OCCCC(=O)O)c(C)c3)c2)C1 CHEMBL4239630 EC50 874.0 nM
CCc1ccc(-n2ccc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cn1 CHEMBL4213710 EC50 877.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1cccc(C(F)(F)F)c1 CHEMBL4079893 EC50 898.0 nM
Cc1ccc(-n2nc(C)c3cnc(-c4ccc([C@H]5C[C@@H]5C(=O)O)cc4)cc32)cc1 CHEMBL4102951 EC50 900.0 nM
O=C(O)CCc1ccc(OCc2ccc(Cl)cc2-c2ccccc2)cc1 CHEMBL2058530 pEC50 912.01 nM
CCc1ccc(-c2nsc(OC)c2COc2ccc(CCC(=O)O)c(C)c2C)cc1 CHEMBL4164722 EC50 920.0 nM
O=C(O)CCc1ccc(OCc2c(C(F)(F)F)ccn2-c2ccc(F)cc2)cc1Cl CHEMBL4207603 EC50 923.0 nM
N#CCc1ccccc1C#Cc1ccc(CCC(=O)O)c(F)c1 CHEMBL2386353 pEC50 933.25 nM
CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL1707 EC50 944.41 nM
O=C(O)CCCOc1ccc(-c2cc(OC(F)(F)F)ccc2F)cc1 CHEMBL3915765 EC50 946.0 nM
Cc1cc(CCC(=O)O)ccc1OCc1ccccc1Cl CHEMBL4101323 EC50 972.0 nM
O=C(O)CCc1ccc(-c2ccc3cnn(-c4ccccn4)c3c2)cc1 CHEMBL4060517 EC50 990.0 nM
Cc1ccc(S(=O)(=O)Nc2c(C)cc(C)cc2C)cc1 CHEMBL3311314 pEC50 1000.0 nM
COc1ccc(S(=O)(=O)Nc2c(C)cc(F)cc2C)cc1 CHEMBL3311196 pEC50 1000.0 nM
O=C(O)CCC1CCC2(CC1)CCN(c1cc(OC(F)(F)F)ccc1Cl)CC2 CHEMBL3897637 EC50 1000.0 nM