Cc1cc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(N)c34)cc2)ccc1F CHEMBL273187 pKi 0.007943 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)cc2)c1 CHEMBL272938 pKi 0.05012 nM
Cc1cc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)ccc1F CHEMBL1986979 pKi 0.0631 nM
Cc1cc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL374044 pKi 0.07943 nM
Cc1cc(NC(=O)Nc2ccc(-c3c(F)ccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL1993996 pKi 0.1 nM
CNC(=O)c1ccccc1Sc1ccc2c(CCc3ccccn3)n[nH]c2c1 CHEMBL3939307 IC50 0.1 nM
CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1 CHEMBL1289926 IC50 0.1 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)c1 CHEMBL1994638 pKi 0.1259 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL373798 pKi 0.1585 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)cc2)c1 CHEMBL271441 pKi 0.1585 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)c1 CHEMBL1967116 pKi 0.1995 nM
Nc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL403402 pKi 0.1995 nM
COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC CHEMBL1289494 IC50 0.21 nM
CCOc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1974254 pKi 0.2512 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3c(F)ccc4[nH]nc(N)c34)cc2)c1 CHEMBL1996255 pKi 0.2512 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C CHEMBL2000335 pKi 0.2512 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3coc4c(-c5cccnc5)cnc(N)c34)cc2)c1 CHEMBL1978601 pKi 0.2512 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cn[nH]c5)cnc(N)c34)cc2)c1 CHEMBL1969102 pKi 0.2512 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)c1 CHEMBL409349 pKi 0.2512 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c12 CHEMBL1980904 pKi 0.3162 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccnc21 CHEMBL1985888 pKi 0.3162 nM
CNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)csc12 CHEMBL2005631 pKi 0.3162 nM
CCCn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1993941 pKi 0.3981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)O)c5)cnc(N)c34)cc2)c1 CHEMBL1989708 pKi 0.3981 nM
CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2004716 pKi 0.3981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN)cnc(N)c34)cc2)c1 CHEMBL1965988 pKi 0.3981 nM
Cn1cc(-c2cnn3c(N)c(-c4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4)cnc23)cn1 CHEMBL1988717 pKi 0.3981 nM
CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCOCC5CC5)c4)n[nH]c2-3)CC1 CHEMBL2002446 pKi 0.3981 nM
COc1ccc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)cc1Cl CHEMBL272453 pKi 0.3981 nM
COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(Cl)cc5)cccc4c3)c2cc1OC CHEMBL429743 IC50 0.5 nM
CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1 CHEMBL1970142 pKi 0.5012 nM
CC(O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL2002165 pKi 0.5012 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4)csc23)cn1 CHEMBL1988387 pKi 0.5012 nM
Cc1cccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)c1 CHEMBL1983963 pKi 0.5012 nM
COCCOCC#Cc1cc(-c2n[nH]c3c2C(=O)c2cc(CN4CCN(C)CC4)ccc2-3)cs1 CHEMBL387971 pKi 0.5012 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccc[nH]2)C(=O)N3)c1)Cc1ccccc1 CHEMBL1980407 pKi 0.631 nM
COc1ccc(-c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)c2c(N)noc12 CHEMBL1973178 pKi 0.631 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)c(F)c3)c12 CHEMBL2000652 pKi 0.631 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3cc(F)c4[nH]c(C)cc4c3)csc12 CHEMBL2006778 pKi 0.631 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc1)CCN2 CHEMBL411903 pKi 0.631 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL220057 pKi 0.631 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1982466 pKi 0.631 nM
Clc1cc2c(cc1Cl)Oc1cc(Cl)c(Cl)cc1O2 CHEMBL30327 Ki 0.697 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(OC(F)(F)F)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5407330 IC50 0.73 nM
COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1 CHEMBL491473 Kd 0.74 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc5c(ccn5C)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5410108 IC50 0.76 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCNS(C)(=O)=O)cnc(N)c34)cc2)c1 CHEMBL1994321 pKi 0.7943 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCCC5)cnc(N)c34)cc2)c1 CHEMBL1973211 pKi 0.7943 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)cncc21 CHEMBL1964692 pKi 0.7943 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN(C)C)cnc(N)c34)cc2)c1 CHEMBL1979883 pKi 0.7943 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cncc21 CHEMBL404366 pKi 0.7943 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 IC50 0.8 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5412144 IC50 0.86 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C)c(F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5403470 IC50 0.88 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5394759 IC50 0.98 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C5CCCC5)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5421802 IC50 0.99 nM
CC(C)(C)NC(=O)Nc1ccc2[nH]nc(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)c2c1 CHEMBL378024 IC50 1.0 nM
CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl CHEMBL406381 IC50 1.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)c1 CHEMBL1988778 pKi 1.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cnc4c(-c5cnn(C)c5)cnn4c3N)cc2)c1 CHEMBL508928 pKi 1.0 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4ccc(F)c(C(F)(F)F)c4)cc3)ccnc21 CHEMBL1966836 pKi 1.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1 CHEMBL1982465 pKi 1.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CC(C)(C)N)cnc(N)c34)cc2)c1 CHEMBL1979577 pKi 1.0 nM
CC(C)(C(N)=O)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1967720 pKi 1.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 IC50 1.0 nM
Cc1n[nH]c2ccc(-c3cc(N[C@@H](CO)c4ccccc4)cnc3-c3cc(F)ccc3O)cc12 CHEMBL4062877 IC50 1.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5393865 IC50 1.03 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5438830 IC50 1.07 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1980297 IC50 1.25 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#Cc5cccnc5)cnc(N)c34)cc2)c1 CHEMBL1971947 pKi 1.259 nM
Cc1ccc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1988075 pKi 1.259 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc1)CCN2 CHEMBL260092 pKi 1.259 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC/C2=C1/C(=O)Nc2ccc(F)cc21 CHEMBL2180602 IC50 1.3 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5411585 IC50 1.41 nM
COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C[C@H](O)CO)c5)cnc(N)c34)cc2)cc1 CHEMBL3646211 IC50 1.45 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)ccn1 CHEMBL1946170 IC50 1.5 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ccnc(N)c34)cc2)c1 CHEMBL394619 pKi 1.585 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 CHEMBL219722 pKi 1.585 nM
Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1966514 pKi 1.585 nM
CCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)csc12 CHEMBL1979516 pKi 1.585 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c12 CHEMBL1976220 pKi 1.585 nM
Cc1cc2cc(-c3csc4c(-c5cccc(S(C)(=O)=O)c5)cnc(N)c34)ccc2[nH]1 CHEMBL1997822 pKi 1.585 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1 CHEMBL402846 pKi 1.995 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1984162 pKi 1.995 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1 CHEMBL404367 pKi 1.995 nM
Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4ccccc4F)cc3)c12 CHEMBL1965570 pKi 1.995 nM
NC(=O)C1CCN(Cc2ccc(-c3cc4ncnc(Nc5ccc6[nH]ccc6c5)c4s3)cc2)CC1 CHEMBL311109 IC50 2.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1 CHEMBL196363 IC50 2.0 nM
FC(F)(F)c1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 CHEMBL377230 IC50 2.0 nM
CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCOc5ccccc5)c4)n[nH]c2-3)CC1 CHEMBL390156 IC50 2.0 nM
Oc1ccc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)cc1O CHEMBL1271641 IC50 2.0 nM
CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc21 CHEMBL572881 IC50 2.0 nM
Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)O)c[nH]4)c3)cc2)c1 CHEMBL3660275 IC50 2.0 nM
CN1CCN(Cc2ccc(NC(=O)CCSc3ccc4c(/C=C/c5ccccn5)n[nH]c4c3)cc2C(F)(F)F)CC1 CHEMBL4439424 GI50 2.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C[C@H](C)O)c5)cnc(N)c34)cc2)c1 CHEMBL3646210 IC50 2.04 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5421149 IC50 2.11 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5410264 IC50 2.18 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1998585 pKi 2.512 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4c3c(N)nn4C)cc2)c1 CHEMBL1985491 pKi 2.512 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4ccc(OC(F)F)cc4)cc3)c12 CHEMBL1972220 pKi 2.512 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccccc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5408069 IC50 2.53 nM
CCCCNC(=O)Nc1ccc(Oc2ncnc3cc(OCCCN4CCCC4)c(OC)cc23)cc1Cl CHEMBL5436823 IC50 2.86 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc5occc5c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5403747 IC50 2.89 nM
Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CNCCN6CCNCC6)cc5)sc34)ccc2[nH]1 CHEMBL79060 IC50 3.0 nM
Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CN(C)CCO)cc5)sc34)ccc2[nH]1 CHEMBL81375 IC50 3.0 nM
CC(C)(CO)NCc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL308498 IC50 3.0 nM
COCCOc1cc2nccc(Nc3cc(O)c(Cl)cc3F)c2cc1OC CHEMBL433936 IC50 3.0 nM
CN1CCN(c2ccc3[nH]c(-c4c(O)nc5cnccc5c4N)nc3c2)CC1 CHEMBL205893 IC50 3.0 nM
c1ccc(COc2ccc3[nH]nc(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c3c2)cc1 CHEMBL377346 IC50 3.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL223360 IC50 3.0 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 IC50 3.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cnc4c(-c5cnn(C)c5)ccn4c3N)cc2)c1 CHEMBL453057 IC50 3.0 nM
CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010872 IC50 3.0 nM
Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)O)c[nH]4)c3)cc2F)c1 CHEMBL3656096 IC50 3.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3nsc(NC(=O)NCCCN4CCOCC4)c3C(N)=O)cc2)c1 CHEMBL3696074 IC50 3.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCCC(=O)O)c[nH]4)c3)cc2F)c1 CHEMBL3656087 IC50 3.0 nM
Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1 CHEMBL3764474 IC50 3.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCCC(CO)C5)sc34)cc2)c1 CHEMBL3932948 IC50 3.0 nM
CCN(CC)CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 CHEMBL3934424 IC50 3.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(-c5ccccc5)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5400860 IC50 3.12 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5409075 IC50 3.12 nM
COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(OCCCN5CCCC5)c(OC)cc34)cc2Cl)c(OC)c1 CHEMBL5411025 IC50 3.16 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4nc(N)nc(N)c34)cc2)c1 CHEMBL1973145 pKi 3.162 nM
CCN(CC)CCCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL1999414 pKi 3.162 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL262433 pKi 3.162 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cc(CO)ccc4F)cc3)c12 CHEMBL1985311 pKi 3.162 nM
Cc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)n[nH]c12 CHEMBL1973937 pKi 3.162 nM
CCN1CCN(c2ccc(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6ccccc6F)c5)nc5ccccn45)n3)cc2)CC1 CHEMBL1981725 pKi 3.162 nM
Nc1ncc(-c2ccncc2)c2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1970083 pKi 3.162 nM
Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2C)n(C)n1 CHEMBL2180604 IC50 3.2 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc(F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5412761 IC50 3.43 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccnn4C4CCCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5425976 IC50 3.52 nM
Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)ccc2F)n(C)n1 CHEMBL2409778 IC50 3.6 nM
Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12 CHEMBL1171837 IC50 3.7 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C(C)C(=O)N(C)C)c5)cnc(N)c34)cc2)cc1 CHEMBL2001485 pKi 3.981 nM
Nc1n[nH]c2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc12 CHEMBL1997623 pKi 3.981 nM
CCC(N)(C#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12)CC CHEMBL1983025 pKi 3.981 nM
CCN(CC)CC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2001257 pKi 3.981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]ncc34)cc2)c1 CHEMBL375284 pKi 3.981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)c1 CHEMBL185569 pKi 3.981 nM
c1ccc(CCCN(c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)n2ccnc2)cc1 CHEMBL312818 IC50 4.0 nM
CC(=O)NCCNCc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL80809 IC50 4.0 nM
OCCOCCNCc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL421326 IC50 4.0 nM
CN(CCO)Cc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL79206 IC50 4.0 nM
OCCCNCc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL77452 IC50 4.0 nM
Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CNCCO)cc5)sc34)ccc2[nH]1 CHEMBL80164 IC50 4.0 nM
Nc1c(-c2nc3cc(N4CCOCC4)ccc3[nH]2)c(O)nc2cnccc12 CHEMBL205108 IC50 4.0 nM
Nc1c(-c2nc3ccccc3[nH]2)c(O)nc2cnccc12 CHEMBL383618 IC50 4.0 nM
CC(C)(C)NC(=O)Nc1cccc2[nH]nc(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)c12 CHEMBL379740 IC50 4.0 nM
c1cc(-c2cnc3c(-c4cn[nH]c4)cnn3c2)ccc1OCCN1CCOCC1 CHEMBL1271532 IC50 4.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCCC(=O)O)c[nH]4)c3)cc2)c1 CHEMBL3656099 IC50 4.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCC(C(=O)O)C5)c[nH]4)c3)cc2F)c1 CHEMBL3656086 IC50 4.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)O)c[nH]4)c3)cc2)c1 CHEMBL3660294 IC50 4.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCc5nn[nH]n5)sc34)cc2)c1 CHEMBL3944753 IC50 4.0 nM
CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5cccc(F)c5)cccc4c3)n2)c1 CHEMBL3740487 IC50 4.2 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccc(F)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5433332 IC50 4.24 nM
COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)(C)O)c5)cnc(N)c34)cc2)cc1 CHEMBL2004290 IC50 4.29 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 4.7 nM
CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5cccnc5)cccc4c3)n2)c1 CHEMBL3739732 IC50 4.9 nM
Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CN6CCOCC6)cc5)sc34)ccc2[nH]1 CHEMBL311111 IC50 5.0 nM
c1cc(Nc2ccc3[nH]ccc3c2)c2sc(-c3ccc(CN4CCOCC4)cc3)cc2n1 CHEMBL312482 IC50 5.0 nM
Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CNCCOCCO)cc5)sc34)ccc2[nH]1 CHEMBL77342 IC50 5.0 nM
Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CNCCCO)cc5)sc34)ccc2[nH]1 CHEMBL78700 IC50 5.0 nM
Nc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL255955 IC50 5.0 nM
CCNC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cccc(C)c4)cc3)ccn2)c1 CHEMBL3656114 IC50 5.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCC(=O)O)c[nH]4)c3)cc2F)c1 CHEMBL3656090 IC50 5.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCC(C(=O)O)C5)c[nH]4)c3)cc2)c1 CHEMBL3656104 IC50 5.0 nM
CCOC(=O)CN1CCN(CCCNC(=O)c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)ccc5F)cc4)c3s2)CC1 CHEMBL3917483 IC50 5.0 nM
CCN(CC)CCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 CHEMBL3961927 IC50 5.0 nM
Cc1cc(NC(=O)Cc2ccc(-c3cccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL1984363 pKi 5.012 nM
COC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)c2c(N)ncnn2c1C CHEMBL1977041 pKi 5.012 nM
Cc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL1970074 pKi 5.012 nM
CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL1980995 pKi 5.012 nM
Nc1ccc(-c2csc3c(C=Cc4nc5ccccc5[nH]4)cnc(N)c23)cc1 CHEMBL1988300 pKi 5.012 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12 CHEMBL394790 pKi 5.012 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(Cl)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1987054 pKi 5.012 nM
Nc1ncc(C=CC(=O)NCCCn2ccnc2)c2scc(-c3ccc(Br)cc3)c12 CHEMBL1994938 pKi 5.012 nM
CNC(=O)c1ncc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(CCO)CC4)c(C(F)(F)F)c3)ccc2C)n1C CHEMBL1784637 IC50 5.2 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(Cl)c3)ncnc2cc1OCCN1CCCC1 CHEMBL5414216 IC50 5.31 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 5.4 nM
COc1cccc(NC(=O)N2CCCc3cc(Nc4ncnc5cc(OC)c(OC)cc45)ccc32)c1 CHEMBL4539051 IC50 5.5 nM
CNC(=O)c1cccc2cc(Oc3ccnc(NC(=O)c4ccc(N5CCN(CCO)CC5)cc4)c3)ccc12 CHEMBL4278642 IC50 5.6 nM
Cc1cccc(C(=O)Nc2cccc([C@H](C)Nc3cncc(Cl)n3)c2)c1 CHEMBL504075 Kd 5.7 nM
OCCNCc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL310740 IC50 6.0 nM
Nc1c(-c2nc3ccc[nH]c-3n2)c(O)nc2cnccc12 CHEMBL204985 IC50 6.0 nM
CN1CCN(CC(=O)Nc2cccc3c2Cc2c-3n[nH]c2-c2csc(C#CCOc3ccccc3)c2)CC1 CHEMBL245377 IC50 6.0 nM
Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCC[C@@H](O)C5)c[nH]4)c3)cc2)c1 CHEMBL3656111 IC50 6.0 nM
COC(=O)CNCCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 CHEMBL3896004 IC50 6.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCN(C)CC5)sc34)cc2F)c1 CHEMBL3934764 IC50 6.0 nM
CCc1cccc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1968406 pKi 6.31 nM
COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(O)CO)c5)cnc(N)c34)cc2)cc1 CHEMBL1965170 pKi 6.31 nM
Cc1cccc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1242373 pKi 6.31 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4sc(C)nc4c3)csc12 CHEMBL1968590 pKi 6.31 nM
Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n(C)n1 CHEMBL2409779 IC50 6.4 nM
c1cc(Nc2ccc3[nH]ccc3c2)c2sc(-c3ccc(CNCCN4CCNCC4)cc3)cc2n1 CHEMBL80540 IC50 7.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2ccc(Cl)cc2)c2ncc[nH]2)C(=O)N3)CC1 CHEMBL2086760 IC50 7.0 nM
CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12 CHEMBL2180605 IC50 7.0 nM
Cc1ccc(NC(=O)Nc2ccc(-c3nsc(NC(=O)NCCCN4CCOCC4)c3C(N)=O)cc2)cc1 CHEMBL3696076 IC50 7.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCOCC5)sc34)cc2F)c1 CHEMBL3918251 IC50 7.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCC(=O)O)sc34)cc2F)c1 CHEMBL3927233 IC50 7.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCC(=O)O)sc34)cc2)c1 CHEMBL3897945 IC50 7.0 nM
CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12 CHEMBL2220486 IC50 7.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL273564 Log IC50 7.079 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CCCCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5424340 IC50 7.09 nM
COc1cc2ncnc(Nc3ccc4c(c3)CCCN4C(=O)Nc3cccc(Cl)c3)c2cc1OC CHEMBL4589270 IC50 7.1 nM
Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)n(C)n1 CHEMBL2348996 IC50 7.4 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5414550 IC50 7.4 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(Br)cc4F)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5405000 IC50 7.45 nM
CC1=[N+](c2ccccc2)C(=O)C(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c(F)c2)C=C1 CHEMBL3765306 IC50 7.7 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL247228 Log IC50 7.762 nM
Cc1cccc(NC(=O)Cc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL1964307 pKi 7.943 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2C)c1 CHEMBL183844 pKi 7.943 nM
Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CHEMBL1967878 pKi 7.943 nM
CNC(=O)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 CHEMBL1988437 pKi 7.943 nM
Cc1cc(C)c(/C=C2\C(=O)Nc3ccccc32)[nH]1 CHEMBL276711 IC50 8.0 nM
CN1CCC(N(C)c2ccc3[nH]c(-c4[nH]nc5ccccc45)nc3c2)CC1 CHEMBL212429 IC50 8.0 nM
CO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL258015 IC50 8.0 nM
COC(=O)CNCCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 CHEMBL3979830 IC50 8.0 nM
COC(=O)C1CCN(C(=O)c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)ccc5F)c(F)c4)c3s2)C1 CHEMBL3966952 IC50 8.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCCC(CO)C5)sc34)cc2F)c1 CHEMBL3967877 IC50 8.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCC(O)CC5)sc34)cc2F)c1 CHEMBL3910242 IC50 8.0 nM
COC(=O)[C@@H]1C[C@@H](O)CN1CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 CHEMBL4109002 IC50 8.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4c3OCCCN4)cc2)no1 CHEMBL4793380 IC50 8.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc5c4oc4ccccc45)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5426431 IC50 8.39 nM
O=C(Nc1cccc(Oc2ccc3nccn3n2)c1)c1cccc(C(F)(F)F)c1 CHEMBL2206666 IC50 8.4 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccccc4F)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5396911 IC50 8.87 nM
NC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)nsc1NC(=O)NCCCN1CCOCC1 CHEMBL3696072 IC50 9.0 nM
COC(=O)CN(CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1)CC(=O)OC CHEMBL3918564 IC50 9.0 nM
CCOC(=O)N1CCN(CCCNC(=O)c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)ccc5F)c(F)c4)c3s2)CC1 CHEMBL3906005 IC50 9.0 nM
COC(=O)CNCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 CHEMBL3890891 IC50 9.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCOC(CO)C5)sc34)cc2F)c1 CHEMBL3964131 IC50 9.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCN(C)CC5)sc34)cc2)c1 CHEMBL3906088 IC50 9.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5419881 IC50 9.29 nM
CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5ccccc5)cccc4c3)n2)c1 CHEMBL3740721 IC50 9.3 nM
Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL101253 Kd 9.6 nM
COc1cc2ncnc(Nc3ccc4c(c3)CCCN4C(=O)Nc3ccc(C(C)=O)cc3)c2cc1OC CHEMBL4548316 IC50 9.6 nM
Nc1c(-c2nc3ccc(N4CCOCC4)[nH]c-3n2)c(O)nc2ccccc12 CHEMBL380702 IC50 10.0 nM
CN1CCN(c2ccc3[nH]c(-c4c(N)c5ccccc5[nH]c4=O)nc3c2)CC1 CHEMBL204427 IC50 10.0 nM
Fc1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 CHEMBL212054 IC50 10.0 nM
O=C(Nc1c[nH]nc1-c1nc2ccc(CN3CCOCC3)cc2[nH]1)NC1CC1 CHEMBL495727 IC50 10.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 IC50 10.0 nM
CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 CHEMBL1822792 IC50 10.0 nM
Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)O)c(C)c34)ccc2[nH]1 CHEMBL377300 Kd 10.0 nM
Nc1ncnc2onc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213505 pKi 10.0 nM
Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1964687 pKi 10.0 nM
CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CHEMBL1983111 pKi 10.0 nM
O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 CHEMBL1973540 pKi 10.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3noc4ncnc(N)c34)cc2)c1 CHEMBL211378 pKi 10.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12 CHEMBL271381 pKi 10.0 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL231209 pKi 10.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCCO)c[nH]4)c3)cc2)c1 CHEMBL3660270 IC50 10.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCc5nn[nH]n5)sc34)cc2)c1 CHEMBL3911718 IC50 10.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCOC(CO)C5)sc34)cc2)c1 CHEMBL3904954 IC50 10.0 nM
COC(=O)[C@@H]1C[C@@H](O)CN1CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 CHEMBL4107173 IC50 10.0 nM
COC(=O)CN(CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1)CC(=O)OC CHEMBL3972255 IC50 10.0 nM
CCOC(=O)CN1CCN(C(=O)CN2CCN(C(=O)c3cc4nccc(Oc5ccc(NC(=O)Nc6cc(C)ccc6F)c(F)c5)c4s3)CC2)CC1 CHEMBL3895671 IC50 10.0 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5406253 IC50 10.9 nM
c1ccc(COc2ccc3c(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)[nH]nc3c2)cc1 CHEMBL209704 IC50 11.0 nM
c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)ccn1 CHEMBL478629 IC50 11.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2cc(F)cc(F)c2)c2nc(C)c[nH]2)C(=O)N3)CC1 CHEMBL2087168 IC50 11.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc(NC(=O)NCCCN4CCOCC4)c3C(N)=O)cc2)c1 CHEMBL3696073 IC50 11.0 nM
COC(=O)CN(CCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1)CC(=O)OC CHEMBL3975323 IC50 11.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCN)sc34)cc2F)c1 CHEMBL3951242 IC50 11.0 nM
[2H]C([2H])([2H])Oc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC([2H])([2H])[2H] CHEMBL3426917 IC50 11.2 nM
Nc1c(-c2nc3cc(N4CCOCC4)ccc3[nH]2)c(=O)[nH]c2ccccc12 CHEMBL204426 IC50 12.0 nM
COc1cc(O)c2c(c1)/C=C/C[C@@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL1668411 IC50 12.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)c2cc1OC CHEMBL2105717 IC50 12.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccccc4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5424131 IC50 12.0 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4c(c3)OCO4)csc12 CHEMBL1993243 pKi 12.59 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371206 pKi 12.59 nM
CCN1CCN(c2ccc(Nc3ncc(C#N)c(Nc4ccc5[nH]ncc5c4)n3)cc2)CC1 CHEMBL1973516 pKi 12.59 nM
COc1ccc(-c2ccc(NC(=O)Nc3ccc(F)c(C)c3)cc2)c2c(N)noc12 CHEMBL1979093 pKi 12.59 nM
Cc1cccc(NC(=O)c2cccc(Oc3ccnc(-c4cc(C(=O)O)c[nH]4)c3)c2)c1 CHEMBL3639549 IC50 13.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NO)c[nH]4)c3)cc2)c1 CHEMBL3660268 IC50 13.0 nM
NC(=O)c1c(-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)nsc1NC(=O)NCCCN1CCOCC1 CHEMBL3696075 IC50 13.0 nM
CCOC(=O)N1CCN(CCNC(=O)c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)ccc5F)c(F)c4)c3s2)CC1 CHEMBL3890520 IC50 13.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL502835 IC50 13.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc(OC(F)(F)F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5432573 IC50 13.7 nM
CN1CCN(c2ccc3[nH]c(-c4c(O)nc5ccccc5c4N)nc3n2)CC1 CHEMBL204524 IC50 14.0 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5cccc(C(F)(F)F)c5)s4)c2C3)CC1 CHEMBL213910 IC50 14.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O CHEMBL2205426 Ki 14.0 nM
COc1cc2c(Oc3ccc(Nc4nn(C)cc4C(=O)NC4CCCCC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL5197792 Kd 14.0 nM
COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)on4)c3)c2cc1OC CHEMBL2029988 Kd 14.0 nM
COC(=O)c1ccc2[nH]nc(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)c2c1 CHEMBL380372 IC50 15.0 nM
O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 CHEMBL202011 IC50 15.0 nM
Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c21 CHEMBL1254007 IC50 15.0 nM
CCNC(=O)c1c[nH]c(-c2cc(Oc3cccc(C(=O)Nc4occc4C)c3)ccn2)c1 CHEMBL3656037 IC50 15.0 nM
CCOC(=O)CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 CHEMBL3919480 IC50 15.0 nM
Cc1ccc(NC(=O)c2ccc(C)c(C(F)(F)F)c2)cc1C#Cc1nn([C@H]2CC[C@H](O)CC2)c2ncnc(N)c12 CHEMBL4798527 IC50 15.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)cc1 CHEMBL194911 Log IC50 15.49 nM
COc1ccc(-c2ccc(NC(=O)Nc3cc(F)cc(F)c3)cc2)c2c(N)noc12 CHEMBL1969190 pKi 15.85 nM
N#Cc1ccc2nc(N)n(-c3nc(-c4ccccc4)cs3)c2c1 CHEMBL1996066 pKi 15.85 nM
CC(C)OCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 CHEMBL150894 IC50 16.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)c2c(N)noc12 CHEMBL430090 IC50 16.0 nM
CC(C)Cn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1084337 IC50 16.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 16.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)OCC(O)CO)c[nH]4)c3)cc2)c1 CHEMBL3660290 IC50 16.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)O)sc34)cc2)c1 CHEMBL3986507 IC50 16.0 nM
CCOC(=O)CCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 CHEMBL3942670 IC50 16.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCCCC5)sc34)cc2)c1 CHEMBL3926026 IC50 16.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCCC5)sc34)cc2)c1 CHEMBL3939959 IC50 16.0 nM
NC(=O)C1CCN(Cc2ccc(-c3cc4nccc(Nc5ccc6[nH]ccc6c5)c4s3)cc2)CC1 CHEMBL431977 IC50 17.0 nM
CCOC(=O)CN1CCN(C(=O)c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)ccc5F)c(F)c4)c3s2)CC1 CHEMBL3965868 IC50 17.0 nM
NCc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL78018 IC50 18.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 IC50 18.0 nM
NC(=O)C1=C(N)C(=O)C=C(Nc2ccccc2O)C1=O CHEMBL2332119 IC50 18.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCC(C(=O)O)C5)sc34)cc2F)c1 CHEMBL3936588 IC50 18.0 nM
CN1CCN(Cc2ccc3c(c2)Cc2c-3n[nH]c2-c2ccc(CN(C)C(=O)Nc3cccc(OC(F)(F)F)c3)s2)CC1 CHEMBL379088 IC50 19.0 nM
CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4sccc34)cc2)CC1 CHEMBL4075720 IC50 19.8 nM
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC CHEMBL1241473 pKi 19.95 nM
O=C1Nc2cc(-c3ccc(O)cc3)ccc2C1=Cc1ccc[nH]1 CHEMBL1980329 pKi 19.95 nM
Cc1cc(C)c(C=C2C(=O)Nc3ccccc32)[nH]1 CHEMBL2002702 pKi 19.95 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)c1 CHEMBL1090356 pKi 19.95 nM
COc1cc2c(Nc3cc(O)c(Cl)cc3F)ncnc2cc1OCC1CCN(C)CC1 CHEMBL2448066 IC50 20.0 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5cccc(Cl)c5)s4)c2C3)CC1 CHEMBL378831 IC50 20.0 nM
COC(=O)C(=O)Nc1cccc2c1Cc1c-2n[nH]c1-c1csc(C#CCOc2ccccc2)c1 CHEMBL246166 IC50 20.0 nM
CN1CCN(c2ccc(C(=O)Nc3cc(-c4ccc(CNC(=O)OCc5ccccc5)cc4)n[nH]3)cc2)CC1 CHEMBL2063323 IC50 20.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2cccc(F)c2)c2nc(C)c[nH]2)C(=O)N3)CC1 CHEMBL2087167 IC50 20.0 nM
CNc1cc2ccc(C#CCOc3ccc(CN4CCNCC4)c(C(F)(F)F)c3)cc2cn1 CHEMBL3355065 IC50 20.0 nM
O=C(Nc1ccc(Oc2ccnc(-c3cc(C(=O)O)c[nH]3)c2)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 CHEMBL3660281 IC50 20.0 nM
Cc1ccoc1C(=O)Nc1cccc(Oc2ccnc(-c3cc(C(=O)N4CC[C@H](O)C4)c[nH]3)c2)c1 CHEMBL3656053 IC50 20.0 nM
c1cc2[nH]nc(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)c2cc1NCC1CCCCC1 CHEMBL379108 IC50 21.0 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CCCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5438648 IC50 21.1 nM
CN(C)CCc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL77782 IC50 22.0 nM
Nc1c(-c2nc3ccc[nH]c-3n2)c(O)nc2ccccc12 CHEMBL204727 IC50 22.0 nM
COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1 CHEMBL24828 IC50 22.0 nM
Cc1c2ccc(N(C)c3ccnc(Nc4ccc(C(=O)Nc5ccccc5N)cc4)n3)cc2nn1C CHEMBL4213341 IC50 22.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O CHEMBL1289601 IC50 22.0 nM
Cc1cnc(Nc2ccc(N3CCC(N(C)CCO)CC3)c(F)c2)nc1-c1cnn(C(C)C)c1 CHEMBL4447631 IC50 22.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)NC5CC5)CC4)c(Cl)c3)c2cc1C(N)=O CHEMBL5201128 IC50 22.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccncc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5405595 IC50 22.4 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 23.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)c12 CHEMBL4160854 IC50 23.0 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccncc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5394767 IC50 23.1 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccc(C#N)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5395547 IC50 23.1 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4ccc5ccccc5c4)cc3)c12 CHEMBL436806 Log IC50 23.99 nM
CC(=O)NCCNCc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL418909 IC50 24.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)c2c(N)noc12 CHEMBL270084 IC50 24.0 nM
COc1cc2c(Nc3cc(O)c(C)cc3F)ncnc2cc1OCC1CCN(C)CC1 CHEMBL1202473 IC50 25.0 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(OC(F)(F)F)cc5)s4)c2C3)CC1 CHEMBL212932 IC50 25.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2cccc(F)c2)c2ncc[nH]2)C(=O)N3)CC1 CHEMBL2086759 IC50 25.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)cn1 CHEMBL4171543 IC50 25.0 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 25.12 nM
Cc1cccc(NC(=O)Nc2ccc(-c3ccc4nccnc4c3N)cc2)c1 CHEMBL507936 pKi 25.12 nM
COc1ccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)cc1OC CHEMBL1964399 pKi 25.12 nM
Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 CHEMBL1969523 pKi 25.12 nM
NC(=O)c1c(OCc2c(F)cc(Br)cc2F)nsc1NC(=O)NCCCCN1CCCC1 CHEMBL253969 pKi 25.12 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4sncc34)cc2)c1 CHEMBL1992242 pKi 25.12 nM
CCN(CC)CCCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)csc12 CHEMBL1996649 pKi 25.12 nM
Cc1cc(C)c2oc(Nc3ccc(-c4cccc(C(N)=O)c4N)cc3F)nc2c1 CHEMBL1990884 pKi 25.12 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(C=Cc3ccccc3)n2)n[nH]1 CHEMBL1983923 pKi 25.12 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 25.12 nM
Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)cn1 CHEMBL3964954 IC50 26.0 nM
Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12 CHEMBL383417 IC50 28.0 nM
c1ccc(Oc2ccc3n[nH]c(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c3c2)cc1 CHEMBL211662 IC50 28.0 nM
c1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 CHEMBL378299 IC50 28.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCCN(C)C)C(C)=O)cc1)c1ccccc1 CHEMBL525909 IC50 28.0 nM
CCCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1082829 IC50 28.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccccc32)c(C)c1CCC(=O)O CHEMBL274654 IC50 28.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2nc(C)c[nH]2)c2ccccc2F)C(=O)N3)CC1 CHEMBL2087169 IC50 29.0 nM
COc1cc2c(Oc3ccc(NC(=O)NC(C)(C)C)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5438351 IC50 29.3 nM
COCCOc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC CHEMBL421961 IC50 30.0 nM
COc1cc2ncnc(Nc3cc(O)c(C)cc3F)c2cc1OC CHEMBL440727 IC50 30.0 nM
COCC(=O)Nc1cccc2c1Cc1c-2n[nH]c1-c1ccsc1 CHEMBL442273 IC50 30.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(-n2c(C)ccc2CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL4644718 IC50 31.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 pKi 31.62 nM
c1ccc(CNc2nc(Nc3cc(C4CC4)[nH]n3)c3sccc3n2)cc1 CHEMBL1997924 pKi 31.62 nM
CN1CCN(C2CCC(n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1997617 pKi 31.62 nM
O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccncc1 CHEMBL153843 IC50 32.0 nM
CN1CCN(Cc2ccc3c(c2)Cc2c-3n[nH]c2-c2ccc(CN(C)C(=O)Nc3cc(F)cc(C(F)(F)F)c3)s2)CC1 CHEMBL378895 IC50 33.0 nM
Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)n(C)n1 CHEMBL2409775 IC50 33.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL3039504 IC50 34.0 nM
Cc1ccc(F)c(NC(=O)c2cccc(Oc3ccnc(-c4cc(C(=O)NO)c[nH]4)c3)c2)c1 CHEMBL3656035 IC50 34.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCN(C)C)C(C)=O)cc1)c1ccccc1 CHEMBL498265 IC50 35.0 nM
Cc1c2ccc(N(C)c3ccnc(Nc4ccc(C(=O)NCCCCCCC(=O)NO)cc4)n3)cc2nn1C CHEMBL4212117 IC50 35.0 nM
Nc1ncnc2scc(-c3ccc4c(C(=O)Nc5ccccc5)cccc4c3)c12 CHEMBL3288526 IC50 35.1 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(F)c3)ncnc2cc1OCc1ccccc1 CHEMBL5401823 IC50 35.1 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(Cl)c(Cl)c5)s4)c2C3)CC1 CHEMBL215948 IC50 36.0 nM
Nc1c(-c2nc3cc(N4CCOCC4)ccc3[nH]2)c(O)nc2ccncc12 CHEMBL381283 IC50 37.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5406841 IC50 37.0 nM
Cc1cccc(NC(=O)N(Cc2ccc(-c3n[nH]c4c3Cc3cc(CN5CCN(C)CC5)ccc3-4)s2)C2CC2)c1 CHEMBL214063 IC50 38.0 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(Br)cc5)s4)c2C3)CC1 CHEMBL211464 IC50 38.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)c2c(N)noc12 CHEMBL269884 IC50 38.0 nM
Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213504 IC50 39.0 nM
O=C1Nc2ccc(C(=O)O)cc2C1=C(c1ccccc1)c1nc2ccccc2[nH]1 CHEMBL2086736 IC50 39.0 nM
CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5ccc6[nH]ccc6c5)c4c3)cc2)CC1 CHEMBL2436978 IC50 39.0 nM
CNC(=O)COc1ccc(Nc2nc(Nc3ccc(C)c(S(N)(=O)=O)c3)ncc2F)cc1 CHEMBL1978099 pKi 39.81 nM
Cc1ccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)cc1 CHEMBL2005828 pKi 39.81 nM
CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 CHEMBL49120 pKi 39.81 nM
O=C1NN=Cc2c[nH]c3cc(NC(=O)C4CC4c4ccccc4)cc1c23 CHEMBL1969502 pKi 39.81 nM
CNCC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL1964441 pKi 39.81 nM
O=C(Cc1ccccc1)Nc1cc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)ccc1Cl CHEMBL2005482 pKi 39.81 nM
Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCC(=O)O CHEMBL2007064 pKi 39.81 nM
COC(C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 CHEMBL1981047 pKi 39.81 nM
CNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)s1 CHEMBL1999484 pKi 39.81 nM
Cc1cccc(Nc2nnc(Cc3ccncc3)c3ccccc23)c1 CHEMBL78303 IC50 40.0 nM
Nc1cc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)ccn1 CHEMBL1271533 IC50 40.0 nM
CN1CCN(c2ccc(C(=O)Nc3cc(-c4cccc(NS(=O)(=O)c5cccc(Cl)c5)c4)n[nH]3)cc2)CC1 CHEMBL1807467 IC50 40.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)N1CCOCCOCCOCC1 CHEMBL3950152 IC50 40.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 CHEMBL576982 Kd 41.0 nM
CCn1cc(-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1 CHEMBL1090479 IC50 42.0 nM
c1ccc(NCCN(c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)n2cccc2)cc1 CHEMBL79215 IC50 43.0 nM
CN1CCN(c2ccc3[nH]c(-c4[nH]nc5ccccc45)nc3c2)CC1 CHEMBL208600 IC50 44.0 nM
Cc1cccc(NC(=O)N(C)Cc2ccc(-c3n[nH]c4c3Cc3ccc(CN5CCN(C)CC5)cc3-4)s2)c1 CHEMBL223220 IC50 44.0 nM
COc1cc2c(Oc3ccc(-c4cnc(Nc5ccc(F)cc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL453737 IC50 45.0 nM
Cc1ccc(C(=C2C(=O)Nc3ccc(C(=O)O)cc32)c2nc3ccccc3[nH]2)cc1 CHEMBL2086740 IC50 45.0 nM
COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c2cc1OC CHEMBL2018882 IC50 46.0 nM
O=C(NCCCN1CCCC1=O)c1cnccc1Nc1nc(-c2cc(Br)ccc2F)nc2nccnc12 CHEMBL234655 IC50 47.0 nM
c1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL76432 IC50 48.0 nM
c1ccc2c(-c3nc4cc(OCCCN5CCCC5)ccc4[nH]3)[nH]nc2c1 CHEMBL208775 IC50 48.0 nM
COCCOc1cc2nncc(Nc3cc(O)c(Cl)cc3F)c2cc1OC CHEMBL150826 IC50 50.0 nM
c1ccc2c(-c3nc4cc(N5CCOCC5)ccc4[nH]3)[nH]nc2c1 CHEMBL209783 IC50 50.0 nM
O=C(Nc1cccc2c1Cc1c-2n[nH]c1-c1ccsc1)c1ccccc1 CHEMBL247585 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@@H]2CN(C)C[C@@H]2C1 CHEMBL3544983 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3977450 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3959516 IC50 50.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3956820 IC50 50.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCOC[C@H]2CO1 CHEMBL3946242 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CCOCC2CO1 CHEMBL3943570 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CN2CCOC[C@H]2CO1 CHEMBL3908311 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1CN2CCOC[C@H]2CO1 CHEMBL3905501 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1CN2CCOC[C@H]2CO1 CHEMBL3924147 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3971781 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOC[C@H]2CO1 CHEMBL3914441 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@H]1CN2CCC[C@@H]2CO1 CHEMBL3917220 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1 CHEMBL3968522 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1CN2CCC[C@@H]2CO1 CHEMBL3977759 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1 CHEMBL3928883 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@H]1CN2CCC[C@H]2CO1 CHEMBL3931623 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1 CHEMBL3959774 IC50 50.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1 CHEMBL3922278 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1 CHEMBL3924998 IC50 50.0 nM
COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1 CHEMBL3896122 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCCC[C@H]2C(=O)N1 CHEMBL3940489 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCCC[C@@H]2C(=O)N1 CHEMBL3900059 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1 CHEMBL3947712 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@@H]2C(=O)N1 CHEMBL3945072 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1 CHEMBL3986135 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1C CHEMBL3983466 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CSC[C@H]2CO1 CHEMBL3917294 IC50 50.0 nM
COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2OC(F)F CHEMBL3921689 IC50 50.0 nM
CCO[C@H]1CO[C@H]2[C@@H]1OC[C@@H]2Oc1cc2ncnc(Nc3ccc(Br)c(Cl)c3)c2cc1OC CHEMBL3907230 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cscn1 CHEMBL3968322 IC50 50.0 nM
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cccnc1 CHEMBL3965901 IC50 50.0 nM
CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(NC(=O)c5cc6ccccc6n5C)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1972584 pKi 50.12 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3coc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1 CHEMBL1983640 pKi 50.12 nM
CN(C(=O)C1CCCCC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2CCC(N)=O CHEMBL485556 pKi 50.12 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 CHEMBL1967531 pKi 50.12 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(=O)O)s3)c2cc1OC CHEMBL474432 pKi 50.12 nM
COc1cc2c(cc1F)C(c1ccccc1Cl)=Nc1c(n[nH]c1C)N2 CHEMBL1980391 pKi 50.12 nM
CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1 CHEMBL1908395 Kd 53.0 nM
CN1CCN(c2ccc(C(=O)Nc3cc(-c4ccc(CNC(=O)Oc5ccccc5)cc4)n[nH]3)cc2)CC1 CHEMBL2063321 IC50 54.0 nM
c1csc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)c1 CHEMBL76751 IC50 55.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)Cn2ccnc2)cc1)c1ccccc1 CHEMBL524453 IC50 55.0 nM
O=C(Nc1cccc(Br)c1)c1nscc1NCc1ccncc1 CHEMBL473287 IC50 55.0 nM
COc1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL201511 IC50 55.0 nM
OCc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 CHEMBL312753 IC50 56.0 nM
Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4n3)c2)n(C)n1 CHEMBL2409781 IC50 56.0 nM
CCCN(Cc1ccc(-c2[nH]nc3c2Cc2cc(CN4CCN(C)CC4)ccc2-3)s1)C(=O)Nc1cccc(C)c1 CHEMBL380068 IC50 59.0 nM
CCN1CCN(Cc2ccc(-c3cc4c(N[C@H](C)c5ccccc5)ncnc4[nH]3)cc2)CC1 CHEMBL587723 IC50 59.0 nM
COC(=O)CNCCCNC(=O)c1cc2nccc(Oc3cccc(C(=O)Nc4cc(C)ccc4F)c3)c2s1 CHEMBL3944929 IC50 59.0 nM
Clc1ccc(Oc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL74850 IC50 60.0 nM
c1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL74587 IC50 60.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCNC(=O)OC(C)(C)C)sc34)cc2F)c1 CHEMBL3980166 IC50 60.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CC(=O)N(C)C)C(C)=O)cc1)c1ccccc1 CHEMBL498088 IC50 61.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2cccc(F)c2)c2nc4ccccc4[nH]2)C(=O)N3)CC1 CHEMBL2086756 IC50 62.0 nM
CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(C#Cc4cncc(N5CCOCC5)c4)c3)cc2C(F)(F)F)CC1 CHEMBL4091628 IC50 62.7 nM
c1ccc(COc2cccc3[nH]nc(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c23)cc1 CHEMBL425247 IC50 63.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCCCCCCCCN)cnc(N)c34)cc2)c1 CHEMBL1978166 pKi 63.1 nM
Nc1ncnc2sc3c(c12)-c1ccc(NC(=O)Nc2ccccc2)cc1CC3 CHEMBL1994693 pKi 63.1 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1970317 pKi 63.1 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1081312 pKi 63.1 nM
O=C(Nc1ccc(-c2cccc3sncc23)cc1)Nc1ccc(F)c(C(F)(F)F)c1 CHEMBL2000801 pKi 63.1 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(Cl)cc5)s4)c2C3)CC1 CHEMBL380243 IC50 64.0 nM
FC(F)(F)c1cccc(-n2cc(-c3ccccc3NCc3ccncc3)nn2)c1 CHEMBL490968 IC50 66.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2cc(F)cc(F)c2)c2nc4ccccc4[nH]2)C(=O)N3)CC1 CHEMBL2086757 IC50 66.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCN(C)C)S(C)(=O)=O)cc1)c1ccccc1 CHEMBL498266 IC50 69.0 nM
Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3)c2)n(C)n1 CHEMBL2409790 IC50 69.0 nM
COc1cc(C2=C(c3c[nH]c4ccc(I)cc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL597492 IC50 69.4 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5401089 IC50 69.9 nM
Clc1ccc(Sc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL74391 IC50 70.0 nM
Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1Cl CHEMBL75196 IC50 70.0 nM
Cc1cc(C(=O)Nc2cccc3c2Cc2c-3n[nH]c2-c2ccsc2)no1 CHEMBL395695 IC50 70.0 nM
O=C(NCc1ccc(-c2cc(NC(=O)c3ccc(OCCN4CCCC4)cc3)[nH]n2)cc1)OCc1ccccc1 CHEMBL2063324 IC50 70.0 nM
FC(F)(F)Oc1cccc(-n2cc(-c3ccccc3NCc3ccncc3)nn2)c1 CHEMBL491502 IC50 72.0 nM
COc1cc(C2=C(c3c[nH]c4ccc(Br)cc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL605957 IC50 72.4 nM
COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 CHEMBL271188 IC50 73.0 nM
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 CHEMBL1908397 Kd 73.0 nM
CN1CCN(c2ccc3[nH]c(-c4c(O)nc5cccnc5c4N)nc3c2)CC1 CHEMBL205405 IC50 74.0 nM
NS(=O)(=O)c1ccc(Nc2ncc(-c3ccc(O)c(O)c3)o2)cc1 CHEMBL1271642 IC50 74.0 nM
Cc1nc(Nc2nc3ccc(-c4cccc(C(=O)Nc5cccc(C(F)(F)F)c5)c4)nc3s2)cc(N2CCNCC2)n1 CHEMBL2148120 Kd 74.0 nM
CCNC(=O)c1cc2nccc(Oc3cccc(C(=O)Nc4cc(C)ccc4F)c3)c2s1 CHEMBL3907284 IC50 74.0 nM
Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL214258 IC50 75.0 nM
CCn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc21 CHEMBL4281823 IC50 76.0 nM
Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL75232 IC50 77.0 nM
COc1ccc2[nH]c(C(=C3C(=O)Nc4ccc(C(=O)O)cc43)c3ccccc3)nc2c1 CHEMBL2086742 IC50 77.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL376951 IC50 79.0 nM
CC(C)(C)c1ccc2nc(-c3n[nH]c4ccccc34)[nH]c2c1 CHEMBL1970104 pKi 79.43 nM
Cc1cc(=O)n2ccc(CN(C)C)c(O)c2n1 CHEMBL1988581 pKi 79.43 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 pKi 79.43 nM
O=C1Nc2ccccc2Nc2nnc(I)cc21 CHEMBL1977346 pKi 79.43 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc4nccnc4c3N)cc2)c1 CHEMBL1971649 pKi 79.43 nM
Cc1cnc(Nc2cccc(S(N)(=O)=O)c2)nc1Nc1ccc(OCC(N)=O)cc1 CHEMBL1988838 pKi 79.43 nM
CCNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)n2)s1 CHEMBL1983715 pKi 79.43 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)c(C)c2)c1 CHEMBL2004311 pKi 79.43 nM
CN1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccc5[nH]ncc5c4)n3)cc2)CC1 CHEMBL1979690 pKi 79.43 nM
Oc1cccc(Nc2nnc(Cc3ccncc3)c3ccccc23)c1 CHEMBL306295 IC50 80.0 nM
COC(=O)C(=O)Nc1cccc2c1Cc1c-2n[nH]c1-c1ccsc1 CHEMBL247388 IC50 80.0 nM
Nc1cc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)ncn1 CHEMBL5288744 IC50 81.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN(C)C(=O)N(C)C)cc1)c1ccccc1 CHEMBL525203 IC50 82.0 nM
Cc1nc(Nc2cc(-c3ccc(CNC(=O)OCc4ccccc4)cc3)n[nH]2)cc(N2CCNCC2)n1 CHEMBL2063436 IC50 82.0 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(F)cc5)s4)c2C3)CC1 CHEMBL384294 IC50 83.0 nM
Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(C(C)(C)C)cc1 CHEMBL393779 IC50 87.0 nM
O=C(Nc1cccc2c1Cc1c-2n[nH]c1-c1ccsc1)c1ccco1 CHEMBL247389 IC50 90.0 nM
c1ccc2c(-c3nc4cc(-n5ccnc5)ccc4[nH]3)[nH]nc2c1 CHEMBL378003 IC50 96.0 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2ccc(OC)cc2)c2nc4ccccc4[nH]2)C(=O)N3)CC1 CHEMBL2086755 IC50 96.0 nM
Cc1cc(CCC(=O)O)c(/C=C2\C(=O)Nc3ccccc32)[nH]1 CHEMBL5278067 IC50 96.0 nM
O=C(Nc1ccc(Cl)cc1)c1ccnn1CCc1ccncc1 CHEMBL397323 IC50 97.0 nM
COC(=O)c1ccc2c(C(Nc3ccc(N(C)C(=O)CN4CCN(C)CC4)cc3)c3ccccc3)c(O)[nH]c2c1 CHEMBL5201102 IC50 99.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(-n2cccc2CN(C)C)cc1)c1ccccc1 CHEMBL4069394 IC50 99.2 nM