CNC(=O)c1ccccc1Sc1ccc2c(CCc3ccccn3)n[nH]c2c1 CHEMBL3939307 IC50 0.1 nM
CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1 CHEMBL1289926 IC50 0.1 nM
COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1 CHEMBL24828 IC50 0.11 nM
Cc1cc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(N)c34)cc2)ccc1F CHEMBL273187 pKi 0.1259 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C)c(F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5403470 IC50 0.18 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C5CCCC5)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5421802 IC50 0.18 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cncc21 CHEMBL404366 pKi 0.1995 nM
COCCOc1cc2ncnc(Oc3cnn(CC(=O)Nc4cccc(OC)c4)c3)c2cc1OC CHEMBL1940109 IC50 0.2 nM
COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC CHEMBL1289494 IC50 0.24 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)cc2)c1 CHEMBL271441 pKi 0.3162 nM
Cc1cc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)ccc1F CHEMBL1986979 pKi 0.3162 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)cc2)c1 CHEMBL272938 pKi 0.3162 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(OC(F)(F)F)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5407330 IC50 0.35 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5412144 IC50 0.38 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5410264 IC50 0.39 nM
Cc1cc(NC(=O)Nc2ccc(-c3c(F)ccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL1993996 pKi 0.3981 nM
Cc1cc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL374044 pKi 0.3981 nM
COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)c1 CHEMBL1940108 IC50 0.4 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5394759 IC50 0.42 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5421149 IC50 0.43 nM
COc1cc(O)c2c(c1)/C=C/C[C@@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL1668411 IC50 0.5 nM
CCCCNC(=O)Nc1ccc(Oc2ncnc3cc(OCCCN4CCCC4)c(OC)cc23)cc1Cl CHEMBL5436823 IC50 0.54 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5393865 IC50 0.58 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc5c(ccn5C)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5410108 IC50 0.58 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 0.7 nM
COc1cc(O)c2c(c1)CCC[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL2012519 IC50 0.73 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL373798 pKi 0.7943 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1 CHEMBL402846 pKi 0.7943 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)c1 CHEMBL1994638 pKi 0.7943 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2[nH]cc(C(=O)O)c2C)cc1 CHEMBL1173411 IC50 0.8 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc5occc5c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5403747 IC50 0.8 nM
COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(OCCCN5CCCC5)c(OC)cc34)cc2Cl)c(OC)c1 CHEMBL5411025 IC50 0.87 nM
O=C(Nc1c[nH]nc1-c1nc2ccc(CN3CCOCC3)cc2[nH]1)NC1CC1 CHEMBL495727 IC50 1.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3c(F)ccc4[nH]nc(N)c34)cc2)c1 CHEMBL1996255 pKi 1.0 nM
Nc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL403402 pKi 1.0 nM
CN1CCC(c2ccc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1 CHEMBL3891581 IC50 1.0 nM
COc1cc2ncc(-c3cccc(NC4CCNC4)n3)n2cc1-c1cnn(C)c1 CHEMBL5176837 IC50 1.0 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccccc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5408069 IC50 1.03 nM
Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2C)n(C)n1 CHEMBL2180604 IC50 1.1 nM
COc1cc(O)c2c(c1)-c1cccc(c1)[C@@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL4453304 IC50 1.1 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccc(F)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5433332 IC50 1.14 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#C[C@@](C)(O)COC)nc21 CHEMBL4303275 IC50 1.2 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(Cl)c3)ncnc2cc1OCCN1CCCC1 CHEMBL5414216 IC50 1.21 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(-c5ccccc5)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5400860 IC50 1.23 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC/C2=C1/C(=O)Nc2ccc(F)cc21 CHEMBL2180602 IC50 1.3 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Kd 1.5 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4ccc(F)c(C(F)(F)F)c4)cc3)ccnc21 CHEMBL1966836 pKi 1.585 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccnc21 CHEMBL1985888 pKi 1.585 nM
NC(=O)C1=C(N)C(=O)C=C(Nc2ccccc2O)C1=O CHEMBL2332119 IC50 1.8 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)c1 CHEMBL409349 pKi 1.995 nM
COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(Cl)cc5)cccc4c3)c2cc1OC CHEMBL429743 IC50 2.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)c3ccsc3)nc21 CHEMBL3644873 IC50 2.0 nM
CC(NC(=O)OC(C)(C)C)c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cc1 CHEMBL3908239 IC50 2.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc(F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5412761 IC50 2.04 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc5c4oc4ccccc45)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5426431 IC50 2.46 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1 CHEMBL196363 pKi 2.512 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cn[nH]c5)cnc(N)c34)cc2)c1 CHEMBL1969102 pKi 2.512 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 pIC50 2.512 nM
CNC(=O)c1ncc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(CCO)CC4)c(C(F)(F)F)c3)ccc2C)n1C CHEMBL1784637 IC50 2.6 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C(C)C)c4)c(F)c3)ncnc2cc1OCc1ccccc1 CHEMBL5401823 IC50 2.66 nM
CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCOc5ccccc5)c4)n[nH]c2-3)CC1 CHEMBL390156 IC50 3.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCCN(C)C)C(C)=O)cc1)c1ccccc1 CHEMBL525909 IC50 3.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 IC50 3.0 nM
COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1 CHEMBL491473 IC50 3.0 nM
CN1CCC(n2cc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1 CHEMBL3982717 IC50 3.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cn[nH]c3)ncc2Cl)CC1 CHEMBL3959306 IC50 3.0 nM
Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C(C)(C)C(N)=O)n2)cn1 CHEMBL3981577 IC50 3.0 nM
Cn1cc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3898744 IC50 3.0 nM
COCCn1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3894588 IC50 3.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL502835 IC50 3.0 nM
CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1 CHEMBL1970142 pKi 3.162 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)c(F)c3)c12 CHEMBL2000652 pKi 3.162 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4c3c(N)nn4C)cc2)c1 CHEMBL1985491 pKi 3.162 nM
Cn1cc(-c2cnn3c(N)c(-c4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4)cnc23)cn1 CHEMBL1988717 pKi 3.162 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c12 CHEMBL1980904 pKi 3.162 nM
O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 CHEMBL1973540 pKi 3.162 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CC(C)(C)N)cnc(N)c34)cc2)c1 CHEMBL1979577 pKi 3.162 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1980297 pKi 3.162 nM
CCN1CCC(Nc2ccc3c(c2)C(=C(c2ccc(Cl)cc2)c2ncc[nH]2)C(=O)N3)CC1 CHEMBL2086760 IC50 3.2 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cccc(OC(F)(F)F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5432573 IC50 3.32 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccccc4F)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5396911 IC50 3.41 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(Br)cc4F)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5405000 IC50 3.56 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)c1 CHEMBL1988778 pKi 3.981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCCC5)cnc(N)c34)cc2)c1 CHEMBL1973211 pKi 3.981 nM
CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2004716 pKi 3.981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN(C)C)cnc(N)c34)cc2)c1 CHEMBL1979883 pKi 3.981 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1 CHEMBL404367 pKi 3.981 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1982466 pKi 3.981 nM
CC(C)OCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 CHEMBL150894 IC50 4.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL376951 IC50 4.0 nM
COCCOCC#Cc1cc(-c2n[nH]c3c2Cc2ccc(Cn4cncn4)cc2-3)cs1 CHEMBL223971 IC50 4.0 nM
CNC(=O)c1cc(COc2nnc(Nc3ccc(Cl)cc3)c3ccoc23)ccn1 CHEMBL2079588 IC50 4.0 nM
Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1 CHEMBL3764474 IC50 4.0 nM
Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3918309 IC50 4.0 nM
CC(C)n1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3911152 IC50 4.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(CCO)c3)ncc2Cl)CC1 CHEMBL3931510 IC50 4.0 nM
COC(=O)c1ccc2c(C(Nc3ccc(N(C)C(=O)CN4CCN(C)CC4)cc3)c3ccccc3)c(O)[nH]c2c1 CHEMBL5201102 IC50 4.0 nM
CCS(=O)(=O)N1CCN(c2ccc(Nc3ncc(C(N)=O)c(NC4CC4)n3)cc2)CC1 CHEMBL4116008 IC50 4.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5411585 IC50 4.18 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5414550 IC50 4.2 nM
CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4sccc34)cc2)CC1 CHEMBL4075720 IC50 4.5 nM
[2H]C([2H])([2H])Oc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC([2H])([2H])[2H] CHEMBL3426917 IC50 4.55 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5438830 IC50 4.93 nM
COc1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL201511 IC50 5.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCN(C)C)C(C)=O)cc1)c1ccccc1 CHEMBL498265 IC50 5.0 nM
COc1cc2c(Oc3ccc(-c4cnc(Nc5ccc(F)cc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL453737 IC50 5.0 nM
CCCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1082829 IC50 5.0 nM
CNC(=O)c1c(N)n(C2CCCCC2)c2nc(C#CC(C)(O)COC)ccc2c1=O CHEMBL3644871 IC50 5.0 nM
Cc1cnc(Nc2cnn(C)c2)nc1CCc1ccccc1C1(C(N)=O)CC1 CHEMBL3973562 IC50 5.0 nM
Cn1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)cn1 CHEMBL3964954 IC50 5.0 nM
NS(=O)(=O)c1cccc(Nc2ncc3ccn(-c4ccccc4)c3n2)c1 CHEMBL1988163 pKi 5.012 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCNS(C)(=O)=O)cnc(N)c34)cc2)c1 CHEMBL1994321 pKi 5.012 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN)cnc(N)c34)cc2)c1 CHEMBL1965988 pKi 5.012 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1 CHEMBL1982465 pKi 5.012 nM
Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CHEMBL1967878 pKi 5.012 nM
CC(C)(C(N)=O)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1967720 pKi 5.012 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccnn4C4CCCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5425976 IC50 5.1 nM
COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O CHEMBL1289601 IC50 5.2 nM
COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)NC5CC5)CC4)c(Cl)c3)c2cc1C(N)=O CHEMBL5201128 IC50 5.2 nM
CC1=[N+](c2ccccc2)C(=O)C(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c(F)c2)C=C1 CHEMBL3765306 IC50 5.5 nM
Cc1[nH]c(/C=C2\C(=O)Nc3cc(NC(=O)Nc4ccccc4)ccc32)c(C)c1C(=O)O CHEMBL1173107 IC50 5.8 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CCCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5438648 IC50 5.82 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CC(=O)N(C)C)C(C)=O)cc1)c1ccccc1 CHEMBL498088 IC50 6.0 nM
CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc21 CHEMBL572881 IC50 6.0 nM
O=C(Nc1ccc(Oc2ncnc3sccc23)cc1)Nc1cccc(Br)c1 CHEMBL3628808 IC50 6.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)c3cccc(OC)c3)nc21 CHEMBL3644865 IC50 6.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(C4CNC4)c3)ncc2Cl)CC1 CHEMBL3963494 IC50 6.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)c2cc1OC CHEMBL2105717 IC50 6.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4c3OCCCN4)cc2)no1 CHEMBL4793380 IC50 6.0 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4)csc23)cn1 CHEMBL1988387 pKi 6.31 nM
CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL1980995 pKi 6.31 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc1)CCN2 CHEMBL411903 pKi 6.31 nM
COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)(C)O)c5)cnc(N)c34)cc2)cc1 CHEMBL2004290 pKi 6.31 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc1)CCN2 CHEMBL260092 pKi 6.31 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)Cn2ccnc2)cc1)c1ccccc1 CHEMBL524453 IC50 7.0 nM
COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OCCN5CCCC5)c(OC)cc34)cn2)c1 CHEMBL1940112 IC50 7.0 nM
O=C(Nc1ccc(Oc2ncnc3ccccc23)cc1)Nc1cccc(Br)c1 CHEMBL3628807 IC50 7.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(C4CCNC4)c3)ncc2Cl)CC1 CHEMBL3893827 IC50 7.0 nM
CN1CCC(n2cc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)C1 CHEMBL3970373 IC50 7.0 nM
Cc1n[nH]cc1Nc1ncc(Cl)c(CCc2ccccc2C2(C(N)=O)CC2)n1 CHEMBL3918369 IC50 7.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(CC(F)F)c3)ncc2Cl)CC1 CHEMBL3891977 IC50 7.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(C4CCNCC4)c3)ncc2C(F)(F)F)CC1 CHEMBL3907640 IC50 7.0 nM
CN1CCC(n2cc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1 CHEMBL3928029 IC50 7.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL247228 Log IC50 7.586 nM
COc1cc2ncnc(Nc3ccc4c(c3)CCCN4C(=O)Nc3cccc(Cl)c3)c2cc1OC CHEMBL4589270 IC50 7.8 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 7.943 nM
COC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)c2c(N)ncnn2c1C CHEMBL1977041 pKi 7.943 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 pKi 7.943 nM
CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCOCC5CC5)c4)n[nH]c2-3)CC1 CHEMBL2002446 pKi 7.943 nM
COc1cccc(NC(=O)Cc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)c1 CHEMBL1940259 IC50 8.0 nM
COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cnn(C(C)C)c4)cc3)c2cc1OC CHEMBL1940274 IC50 8.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cccnc3)ncc2Cl)CC1 CHEMBL3922174 IC50 8.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(CC(F)(F)F)c3)ncc2Cl)CC1 CHEMBL3938170 IC50 8.0 nM
COc1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3963900 IC50 8.0 nM
Cc1cnc(Nc2ccc(N3CCC(N(C)CCO)CC3)c(F)c2)nc1-c1cnn(C(C)C)c1 CHEMBL4447631 IC50 8.0 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1 CHEMBL3989870 Ki 8.0 nM
O=C(Nc1ccc(Cl)cc1)Nc1ccc2c(c1)NC(=O)/C2=C\c1ccc[nH]1 CHEMBL1172886 IC50 8.7 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 IC50 8.9 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5401089 IC50 8.97 nM
CC(C)Cn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1084337 IC50 9.0 nM
COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c2cc1OC CHEMBL2018882 IC50 9.0 nM
CN1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cc2)CC1 CHEMBL3948670 IC50 9.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(C4CCNCC4)c3)ncc2Cl)CC1 CHEMBL3954050 IC50 9.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cn[nH]c2)ncc1Cl CHEMBL3960972 IC50 9.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCN(C)CC3)c2)ncc1Cl CHEMBL3970712 IC50 9.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 9.1 nM
COc1cc(O)c2c(c1)-c1cccc(c1)[C@H](O)[C@@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL4452766 IC50 9.2 nM
CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)Nc5cccc(F)c5)cc4)ncnc3c2)CC1 CHEMBL1934327 IC50 9.6 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(-n2cccc2CN(C)C)cc1)c1ccccc1 CHEMBL4069394 IC50 9.6 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5409075 IC50 9.83 nM
COc1cc(O)c2c(c1)-c1cccc(c1)[C@@H](O)[C@H](O)C(=O)C/C=C/[C@H](C)OC2=O CHEMBL4530473 IC50 9.9 nM
CO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL258015 IC50 10.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN(C)C(=O)N(C)C)cc1)c1ccccc1 CHEMBL525203 IC50 10.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCN(C)C)S(C)(=O)=O)cc1)c1ccccc1 CHEMBL498266 IC50 10.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL223360 pKi 10.0 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)cncc21 CHEMBL1964692 pKi 10.0 nM
CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12 CHEMBL2180605 IC50 10.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)cc3)ncc2C(F)(F)F)CC1 CHEMBL3909401 IC50 10.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)cc3)ncc2Cl)CC1 CHEMBL3917694 IC50 10.0 nM
CN1CCC(c2ccc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cc2)CC1 CHEMBL3893200 IC50 10.0 nM
CC(=O)NC(C)c1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cc1 CHEMBL3913725 IC50 10.0 nM
CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12 CHEMBL2220486 IC50 10.0 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CCCCC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5424340 IC50 10.9 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2[nH]c(C)c(CC(=O)O)c2C)cc1 CHEMBL1173150 IC50 11.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)nc3)ncc2Cl)CC1 CHEMBL3980022 IC50 11.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccccc3)ncc2Cl)CC1 CHEMBL3981765 IC50 11.0 nM
COc1cc2ncnc3c2cc1OCCCCCN(C)Cc1ccc(Br)cc1N3 CHEMBL3109738 IC50 11.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccncc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5405595 IC50 11.6 nM
CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cn1 CHEMBL1940273 IC50 12.0 nM
Cc1nn(C)cc1Nc1ncc(Cl)c(CCc2ccccc2C2(C(N)=O)CC2)n1 CHEMBL3925575 IC50 12.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1Cl CHEMBL3906184 IC50 12.0 nM
Cc1cnc(Nc2cnn(C3CCN(C)CC3)c2)nc1CCc1ccccc1C1(C(N)=O)CC1 CHEMBL3944075 IC50 12.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)c2c(N)noc12 CHEMBL1973178 pKi 12.59 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3cc(F)c4[nH]c(C)cc4c3)csc12 CHEMBL2006778 pKi 12.59 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1984162 pKi 12.59 nM
CCC(N)(C#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12)CC CHEMBL1983025 pKi 12.59 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2ccc[nH]2)cc1 CHEMBL1173149 IC50 12.8 nM
O=C(Nc1ccc(-c2ccc3ccccc3c2)cc1)Nc1ccc2c(c1)NC(=O)/C2=C\c1ccc[nH]1 CHEMBL1172838 IC50 13.0 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2[nH]c(C)c(CCC(=O)O)c2C)cc1 CHEMBL1173541 IC50 13.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL3039504 IC50 13.0 nM
Cc1cnc(Nc2cn[nH]c2)nc1CCc1ccccc1C1(C(N)=O)CC1 CHEMBL3949389 IC50 13.0 nM
O=C(Nc1cccc(Cl)c1)Nc1ncc(CCNc2ncnc3ccsc23)s1 CHEMBL518051 IC50 14.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)c3ccccc3)nc21 CHEMBL3644870 IC50 14.0 nM
CC(N)c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cc1 CHEMBL3890328 IC50 14.0 nM
COc1cccc(NC(=O)N2CCCc3cc(Nc4ncnc5cc(OC)c(OC)cc45)ccc32)c1 CHEMBL4539051 IC50 14.2 nM
Cc1cnc(Nc2cnn(C)c2)nc1CCc1ccccc1C(C)C(N)=O CHEMBL3986746 IC50 15.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C)c2)ncc1C(F)(F)F CHEMBL3975577 IC50 15.0 nM
Oc1c2ccccc2c2c3c(cccc13)N=N2 CHEMBL1725279 pKi 15.85 nM
Cc1cc2cc(-c3csc4c(-c5cccc(S(C)(=O)=O)c5)cnc(N)c34)ccc2[nH]1 CHEMBL1997822 pKi 15.85 nM
CCOc1cccc2c1c(/C=C1\C(=O)NN=C1c1snnc1C)cn2C CHEMBL398610 IC50 16.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C)c2)ncc1Cl CHEMBL3933224 IC50 16.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4cnn(C)c4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5406841 IC50 16.6 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 17.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cn[nH]c2)ncc1C(F)(F)F CHEMBL3946260 IC50 17.0 nM
COc1cc2c(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5406253 IC50 17.1 nM
COc1cc2ncnc(Nc3ccc4c(c3)CCCN4C(=O)Nc3ccc(C(C)=O)cc3)c2cc1OC CHEMBL4548316 IC50 17.3 nM
O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccncc1 CHEMBL153843 IC50 18.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc2[nH]c(C(=O)N3CCN(C)CC3)cc2c1)c1ccccc1 CHEMBL4165429 IC50 18.2 nM
O=C(Nc1n[nH]c2cc(C(=O)N[C@H](CN3CCCC3)c3ccccc3)sc12)c1ccc(N2CCOCC2)cc1 CHEMBL1258913 IC50 19.0 nM
C[C@H](C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCN(C)CC3)c2)ncc1C(F)(F)F CHEMBL3895625 IC50 19.0 nM
COc1cc2c(Oc3ccc(Nc4nn(C)cc4C(=O)NC4CCCCC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL5197792 Kd 19.0 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C CHEMBL2000335 pKi 19.95 nM
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC CHEMBL1241473 pKi 19.95 nM
CNC(=O)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 CHEMBL1988437 pKi 19.95 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccnnc3)ncc2Cl)CC1 CHEMBL3899188 IC50 20.0 nM
CCn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc21 CHEMBL4281823 IC50 20.0 nM
COc1cc(C2=C(c3c[nH]c4ccc(Br)cc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL605957 IC50 21.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC3(O)CCC3)nc21 CHEMBL3644863 IC50 21.0 nM
COc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc(N(C)C)cn4)cc3)c2cc1OC CHEMBL1940118 IC50 22.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CNC4)cc3)ncc2C(F)(F)F)CC1 CHEMBL3903877 IC50 22.0 nM
CC(=O)N1CCC(n2cc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C(C)C(N)=O)n3)cn2)CC1 CHEMBL3967214 IC50 22.0 nM
CC(N)c1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cc1 CHEMBL3892486 IC50 22.0 nM
O=C(Nc1ccccc1)Nc1ccc2c(c1)NC(=O)/C2=C\c1ccc[nH]1 CHEMBL1173482 IC50 22.4 nM
Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL214258 IC50 23.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(C)O)nc21 CHEMBL3644860 IC50 23.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)COC)nc21 CHEMBL3644872 IC50 23.0 nM
Cc1cnc(Nc2ccc(C3CCN(C)CC3)nc2)nc1CCc1ccccc1C1(C(N)=O)CC1 CHEMBL3926124 IC50 23.0 nM
O=C(O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)cc3)ncc2C(F)(F)F)CCC1 CHEMBL4113489 IC50 23.0 nM
COc1cc(O)c2c(c1)-c1cccc(c1)[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL4533447 IC50 23.0 nM
Cc1nc2c(c(Nc3c[nH]nc3C(=O)Nc3ccc(N4CCNCC4)cc3)n1)CCC2 CHEMBL4163870 IC50 23.01 nM
CCCNC(=O)c1cc(Oc2ccc(NC(=O)c3cc4cccnc4n(-c4ccc(F)cc4)c3=O)cc2)ccn1 CHEMBL4204920 IC50 23.6 nM
O=C1Nc2ccc(F)cc2/C1=C1/Nc2ccccc2/C1=N\OCCN1CCNCC1 CHEMBL4791998 IC50 23.8 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(NC(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL465015 IC50 24.0 nM
COc1cccc(NC(=O)Cn2cc(Nc3ncnc4cc(OC)c(OC)cc34)cn2)c1 CHEMBL1940104 IC50 25.0 nM
Cc1cnc(Nc2cnn(C)c2)nc1CCc1ccccc1[C@@H](C)C(N)=O CHEMBL4114236 IC50 25.0 nM
NS(=O)(=O)c1cccc(Nc2ncc3ccn(Cc4ccccc4)c3n2)c1 CHEMBL1993424 pKi 25.12 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 25.12 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c1C CHEMBL1990885 pKi 25.12 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C(F)(F)F)nc3)ncc2Cl)CC1 CHEMBL3908745 IC50 26.0 nM
Cc1cccc(C(=O)Nc2cccc([C@H](C)Nc3cncc(Cl)n3)c2)c1 CHEMBL504075 Kd 27.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 Kd 27.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1C(F)(F)F CHEMBL3950340 IC50 27.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCN(C)CC3)c2)ncc1C(F)(F)F CHEMBL3900906 IC50 27.0 nM
COc1cc(O)c2c(c1)-c1cccc(c1)CCC(=O)/C=C\C[C@H](C)OC2=O CHEMBL4515000 IC50 27.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)nc3)ncc2C(F)(F)F)CC1 CHEMBL3931458 IC50 28.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCN(C)CC3)nc2)ncc1C(F)(F)F CHEMBL3938508 IC50 28.0 nM
CCn1cc(NC(=O)Cc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)cn1 CHEMBL1940272 IC50 29.0 nM
COc1cc(C2=C(c3c[nH]c4ccc(I)cc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL597492 IC50 29.51 nM
COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)cc(OC)c34)cn2)c1 CHEMBL1940113 IC50 30.0 nM
CNc1cc2ccc(C#CCOc3ccc(CN4CCNCC4)c(C(F)(F)F)c3)cc2cn1 CHEMBL3355065 IC50 30.0 nM
O=C1c2ccc(-c3cnc4[nH]ccc4c3)cc2OCCN1Cc1ccc(F)cc1 CHEMBL5181357 IC50 30.0 nM
COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OCCN5CCCCC5)cc34)cn2)c1 CHEMBL1940111 IC50 31.0 nM
Cc1nc(Nc2nc3ccc(-c4cccc(C(=O)Nc5cccc(C(F)(F)F)c5)c4)nc3s2)cc(N2CCNCC2)n1 CHEMBL2148120 Kd 31.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCNCC3)nc2)ncc1Cl CHEMBL3957259 IC50 31.0 nM
C[C@@H](C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1C(F)(F)F CHEMBL4112177 IC50 31.0 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1 CHEMBL1991429 pKi 31.62 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#Cc5cccnc5)cnc(N)c34)cc2)c1 CHEMBL1971947 pKi 31.62 nM
Cc1cccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)c1 CHEMBL1983963 pKi 31.62 nM
O=C(NCCCCCCNC(=O)Nc1cccnc1)Nc1cccnc1 CHEMBL1998193 pKi 31.62 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(Cl)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1987054 pKi 31.62 nM
NC1C2CN(c3nc4c(cc3F)c(=O)c(C(=O)O)cn4-c3ccc(F)cc3F)CC12 CHEMBL1624529 pKi 31.62 nM
CN1CCN(C2CCC(n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1997617 pKi 31.62 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN2CCCCC2)cc1)c1ccccc1 CHEMBL497049 IC50 32.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCN(C)CC3)nc2)ncc1Cl CHEMBL3892658 IC50 32.0 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2[nH]c(C)c(C(=O)O)c2C)cc1 CHEMBL1173174 IC50 32.9 nM
Cc1[nH]c(/C=C2\C(=O)Nc3cc(NC(=O)Nc4ccccc4)ccc32)c(C)c1CC(=O)O CHEMBL1172422 IC50 34.0 nM
CNC(=O)c1c(N)n(C2CCOCC2)c2nc(C#CC(C)(O)COC)ccc2c1=O CHEMBL3644866 IC50 34.0 nM
CCn1cc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cn1 CHEMBL1940116 IC50 35.0 nM
COc1cc(C2=C(c3c[nH]c4ccccc34)CNC2=O)cc(OC)c1OC CHEMBL529663 IC50 37.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(O)C3CC3)nc21 CHEMBL3644862 IC50 37.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)c12 CHEMBL4160854 IC50 37.0 nM
C[C@@H](C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCN(C)CC3)c2)ncc1C(F)(F)F CHEMBL4110384 IC50 38.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 CHEMBL576982 Kd 38.0 nM
CCSCc1ccc2c(c1)c1c3c(c4c5cc(CSCC)ccc5n5c4c1n2[C@H]1C[C@](O)(C(=O)OC)[C@]5(C)O1)CNC3=O CHEMBL290352 IC50 39.0 nM
Cc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2[nH]c(C)c(C(=O)O)c2C)cc1 CHEMBL1172420 IC50 39.0 nM
COc1cc2ncnc(Oc3cnn(CC(=O)Nc4ccc(N(C)C)cn4)c3)c2cc1OC CHEMBL1940107 IC50 39.0 nM
NC(=O)C1(c2ccccc2CCc2nc(Nc3cncnc3)ncc2Cl)CC1 CHEMBL3970850 IC50 39.0 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C(C)C(=O)N(C)C)c5)cnc(N)c34)cc2)cc1 CHEMBL2001485 pKi 39.81 nM
Cc1cnc(Nc2cccc(S(N)(=O)=O)c2)nc1Nc1ccc(OCC(N)=O)cc1 CHEMBL1988838 pKi 39.81 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL220057 pKi 39.81 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)c1 CHEMBL1090356 pKi 39.81 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c12 CHEMBL1976220 pKi 39.81 nM
C[C@H](Nc1nc(Nc2cn(C)cn2)c2cc[nH]c2n1)c1ncc(F)cn1 CHEMBL3116050 IC50 40.0 nM
CNC(=O)c1c(N)n(CC2CCCO2)c2nc(C#CC(C)(C)O)ccc2c1=O CHEMBL3644867 IC50 40.0 nM
Cc1cnc(Nc2cnn(C)c2)nc1CCc1ccccc1[C@H](C)C(N)=O CHEMBL3913700 IC50 41.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3cc(NC(=O)Nc4ccc(Cl)cc4)ccc32)c(C)c1C(=O)O CHEMBL1172421 IC50 42.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)ccn1 CHEMBL1946170 IC50 42.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)CO)nc21 CHEMBL3644869 IC50 43.0 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 CHEMBL4063500 IC50 43.0 nM
CC(=O)c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3920100 IC50 44.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cccnc2)ncc1Cl CHEMBL3971001 IC50 44.0 nM
Cc1ccc(Nc2ncc(Cl)c(CCc3ccccc3C(C)C(N)=O)n2)cn1 CHEMBL3915153 IC50 45.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)cn1 CHEMBL4171543 IC50 45.0 nM
C[C@@H](Nc1ccc2[nH]nc(/C=C/c3ccccn3)c2c1)c1cc(F)cc(F)c1 CHEMBL4792981 Kd 45.0 nM
CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC3(O)CCCC3)nc21 CHEMBL3644861 IC50 46.0 nM
Cc1cnc(Nc2ccc(C(C)N)cc2)nc1CCc1ccccc1C1(C(N)=O)CC1 CHEMBL3901596 IC50 46.0 nM
Cc1c2ccc(N(C)c3ccnc(Nc4ccc(C(=O)Nc5ccccc5N)cc4)n3)cc2nn1C CHEMBL4213341 IC50 46.0 nM
O=C(Nc1ccc(Nc2ncnc3ccccc23)cc1)Nc1cccc(Br)c1 CHEMBL3628797 IC50 47.0 nM
Cc1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)n[nH]1 CHEMBL3937825 IC50 47.0 nM
COc1c(Nc2ncc(Cl)c(N[C@H]3[C@@H](C(N)=O)[C@@H]4C=C[C@H]3C4)n2)ccc2c1CC[C@@H](N1CCOCC1)CC2 CHEMBL2064666 IC50 48.0 nM
[C-]#[N+]c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3948616 IC50 48.0 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccncc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5394767 IC50 48.2 nM
COc1cc2c(Oc3ccc(NC(=O)NCc4ccc(C#N)cc4)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5395547 IC50 48.3 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5419881 IC50 48.5 nM
Cc1cc(C)c(/C=C2\C(=O)Nc3ccccc32)[nH]1 CHEMBL276711 IC50 50.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 50.0 nM
Nc1cc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)ncn1 CHEMBL5288744 IC50 50.0 nM
CNC(=O)COc1ccc(Nc2nc(Nc3ccc(C)c(S(N)(=O)=O)c3)ncc2F)cc1 CHEMBL1978099 pKi 50.12 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL262433 pKi 50.12 nM
COc1ccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)cc1OC CHEMBL1964399 pKi 50.12 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)c1 CHEMBL1090360 pKi 50.12 nM
O=C1NN=Cc2c[nH]c3cc(NC(=O)C4CC4c4ccccc4)cc1c23 CHEMBL1969502 pKi 50.12 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371206 pKi 50.12 nM
Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4ccccc4F)cc3)c12 CHEMBL1965570 pKi 50.12 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2C)c1 CHEMBL183844 pKi 50.12 nM
Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 CHEMBL1969523 pKi 50.12 nM
COc1cc2ncnc(Nc3cnn(CC(=O)Nc4cccc(F)c4)c3)c2cc1OC CHEMBL1940103 IC50 51.0 nM
O=C(Nc1cccc(-c2cncc3ccccc23)c1)c1ccccc1NCc1ccncc1 CHEMBL347537 IC50 52.0 nM
NC(=O)c1c(OCc2c(F)cc(Br)cc2F)nsc1NC(=O)NCCCCN1CCCC1 CHEMBL253969 IC50 54.2 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccccc4)c(F)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5424131 IC50 54.6 nM
Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)O)c(C)c34)ccc2[nH]1 CHEMBL377300 Kd 56.0 nM
COc1cccc(NC(=O)Cn2cc(Oc3ccnc4cc(OC)c(OC)cc34)cn2)c1 CHEMBL1940115 IC50 57.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(C(=O)N(C)CCN(C)C)cc1)c1ccccc1 CHEMBL525550 IC50 59.0 nM
Cc1c2cc(cc1C(=O)Nc1cc(CN3CCN(C)CC3)cc(C3CC3)c1)OCCCCCCCNC(=O)c1ccc3ncc(n3n1)C#C2 CHEMBL5423601 IC50 59.37 nM
COc1cc2c(Oc3ccc(-c4nc5ccccc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595143 EC50 60.0 nM
CC(N)c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 CHEMBL3986325 IC50 60.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 61.0 nM
CN1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1 CHEMBL3892145 IC50 63.0 nM
OC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1991674 pKi 63.1 nM
COc1cccc(C(C)NC(=O)N2CC=C(c3c[nH]c4ncccc34)CC2)c1 CHEMBL1965845 pKi 63.1 nM
O=c1c(NCCc2ccc(Oc3ccccc3)cc2)c(Nc2ccncc2)c1=O CHEMBL1999321 pKi 63.1 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12 CHEMBL394790 pKi 63.1 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1ccccc1 CHEMBL1999931 pKi 63.1 nM
Nc1ncc(-c2ccncc2)c2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1970083 pKi 63.1 nM
CC(C)Oc1cc(-n2cnc3ccc(N[C@@H](C)c4ccc(F)cn4)nc32)n[nH]1 CHEMBL2151321 IC50 64.0 nM
CC(NC(=O)OC(C)(C)C)c1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cc1 CHEMBL3983276 IC50 64.0 nM
Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL75232 IC50 64.0 nM
CNC(=O)c1c(N)n(Cc2ccccn2)c2nc(C#CC(C)(O)COC)ccc2c1=O CHEMBL3644868 IC50 65.0 nM
COc1cc(C2=C(c3c[nH]c4ccc(F)cc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL606168 IC50 66.0 nM
O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2c(c1)NC(=O)/C2=C\c1ccc[nH]1 CHEMBL1172887 IC50 68.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595615 IC50 69.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 CHEMBL1081198 IC50 71.0 nM
CC(C)n1nc(-c2cc(C3CC3)on2)c2c(N)ncnc21 CHEMBL3753341 IC50 72.0 nM
Cc1cc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(C)c34)cc2)ccc1N1CCOCC1 CHEMBL4072731 IC50 72.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN(C)C)cc1)c1ccccc1 CHEMBL498105 IC50 73.0 nM
CCn1cc(-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1 CHEMBL1090479 IC50 74.0 nM
CC[C@H](C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCNCC3)cc2)ncc1C(F)(F)F CHEMBL3918323 IC50 75.0 nM
CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 CHEMBL1822792 IC50 78.0 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 78.0 nM
Nc1ncnc2onc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213505 pKi 79.43 nM
O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1)c1c(F)cccc1F CHEMBL2006715 pKi 79.43 nM
Cc1ccc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1988075 pKi 79.43 nM
Nc1ncc(C=CC(=O)NCCCn2ccnc2)c2scc(-c3ccc(Br)cc3)c12 CHEMBL1994938 pKi 79.43 nM
Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1966514 pKi 79.43 nM
CCN1CCC(n2cc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C(C)C(N)=O)n3)cn2)CC1 CHEMBL3970470 IC50 86.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cc1 CHEMBL381207 IC50 87.0 nM
O=C(Nc1ccc(-c2ccccc2)cc1)Nc1ccc2c(c1)NC(=O)/C2=C\c1ccc[nH]1 CHEMBL1172837 IC50 88.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCN(C(C)C)CC3)c2)ncc1C(F)(F)F CHEMBL3938601 IC50 89.0 nM
CCC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCNCC3)cc2)ncc1C(F)(F)F CHEMBL3946227 IC50 91.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL514499 IC50 92.0 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2ccc[nH]2)cc1OC CHEMBL1172814 IC50 92.0 nM
C[C@H](C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1C(F)(F)F CHEMBL3892144 IC50 93.0 nM
CNC(=O)c1cc(-n2ccc3cc(NC(=O)Nc4ccc(N5CCN(C)CC5)c(C(F)(F)F)c4)ccc32)ccn1 CHEMBL4797840 IC50 95.7 nM
Cc1cc(N2CCOCC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 CHEMBL2005886 pKi 100.0 nM
Cc1cc(O)ccc1-n1c2cc(Cl)ccc2c(=O)c2c(N)nc(N)nc21 CHEMBL1995592 pKi 100.0 nM
CC1(O)CC(c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)nccn23)C1 CHEMBL1996234 pKi 100.0 nM
CCN(CC)CC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2001257 pKi 100.0 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4sc(C)nc4c3)csc12 CHEMBL1968590 pKi 100.0 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(N3CCN(C(C)=O)CC3)ccc2OC)ncc1Br CHEMBL1971029 pKi 100.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(=O)O)s3)c2cc1OC CHEMBL474432 pKi 100.0 nM
NC(COc1cncc(-c2cc3ccncc3s2)c1)Cc1c[nH]c2ccccc12 CHEMBL1966524 pKi 100.0 nM
COc1cc2ncnc(Nc3cnn(CC(=O)Nc4ccc(N(C)C)cc4)c3)c2cc1OC CHEMBL1940105 IC50 101.0 nM
COc1cc2c(Oc3ccc(NC(=O)NC(C)(C)C)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5438351 IC50 101.42 nM
CC[C@@H](C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCNCC3)cc2)ncc1C(F)(F)F CHEMBL4107713 IC50 103.0 nM
CN1CCN(c2ccc(-c3cc4c(N5CCN(C(=O)Nc6ccc(Cl)c(C(F)(F)F)c6)CC5)ncnc4s3)cc2)CC1 CHEMBL4874448 IC50 110.4 nM
Cc1c2ccc(N(C)c3ccnc(Nc4ccc(C(=O)NCCCCCCC(=O)NO)cc4)n3)cc2nn1C CHEMBL4212117 IC50 113.0 nM
COc1cc(O)c2c(c1)CCC[C@H](O)[C@H](O)C(=O)CCC[C@H](C)OC2=O CHEMBL4099337 IC50 114.5 nM
CC(C)(O)COc1ccc2c(Oc3ccc(Nc4nccc5[nH]cc(-c6ccccc6)c(=O)c45)cc3F)ccnc2c1 CHEMBL4747900 IC50 116.0 nM
COc1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C(C)C(N)=O)n2)cn1 CHEMBL3968164 IC50 118.0 nM
COc1cc2c(Oc3ccc(-c4cnc(Cc5ccccc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL505896 IC50 120.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 120.0 nM
O=C(NCCCN1CCCC1=O)c1cnccc1Nc1nc(-c2cc(Br)ccc2F)nc2nccnc12 CHEMBL234655 IC50 123.0 nM
CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl CHEMBL406381 IC50 125.0 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 125.89 nM
Cc1cc(NC(=O)Cc2ccc(-c3cccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL1984363 pKi 125.89 nM
CCc1cccc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1968406 pKi 125.89 nM
COCCOCC#Cc1cc(-c2n[nH]c3c2C(=O)c2cc(CN4CCN(C)CC4)ccc2-3)cs1 CHEMBL387971 pKi 125.89 nM
COc1ccc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)cc1Cl CHEMBL272453 pKi 125.89 nM
Cn1c2ccccc2c2c3c(c4c5ccccc5n(CCC#N)c4c21)CNC3=O CHEMBL302449 pKi 125.89 nM
COc1cccc(COc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)c1 CHEMBL1940267 IC50 128.0 nM
COc1cc2c(Oc3ccc(-c4nc5ccccc5s4)cc3)ncnc2cc1OCCCN1CCCC1 CHEMBL595373 IC50 140.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(-n3nc(-c4ccc(OCCN5CCOCC5)cc4)c4c(N)ncnc43)cc2)no1 CHEMBL4101411 IC50 141.0 nM
Cc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2ccc[nH]2)cc1 CHEMBL1172815 IC50 146.8 nM
Cc1cccc(C)c1/C=C/n1cnc2c(Nc3ccc(P(C)(C)=O)cc3)ncnc21 CHEMBL488840 IC50 151.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccnnc2)ncc1Cl CHEMBL3976872 IC50 154.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4nc(N)nc(N)c34)cc2)c1 CHEMBL1973145 pKi 158.49 nM
CC(C)(C)c1ccc2nc(-c3n[nH]c4ccccc34)[nH]c2c1 CHEMBL1970104 pKi 158.49 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4c(c3)OCO4)csc12 CHEMBL1993243 pKi 158.49 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cc(CO)ccc4F)cc3)c12 CHEMBL1985311 pKi 158.49 nM
O=C1Cc2c([nH]c3ccc([N+](=O)[O-])cc23)-c2ccccc2N1 CHEMBL50894 pKi 158.49 nM
Cc1cccc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1242373 pKi 158.49 nM
COC(C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 CHEMBL1981047 pKi 158.49 nM
CCc1cc(Nc2nccc(-c3c(-c4ccc(OC)c(C(=O)Nc5c(F)cccc5F)c4)nc4ccccn34)n2)c(OC)cc1N1CCC(N2CCN(S(C)(=O)=O)CC2)CC1 CHEMBL466397 IC50 159.0 nM
CC(C(N)=O)c1ccccc1CCc1nc(Nc2cncnc2)ncc1Cl CHEMBL3981693 IC50 160.0 nM
CO[C@@H](C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 CHEMBL402548 IC50 161.0 nM
c1cn(Cc2ccc3c(c2)-c2[nH]nc(-c4ccsc4)c2C3)cn1 CHEMBL212084 IC50 169.0 nM
CCn1ccc(NC(=O)Cc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)n1 CHEMBL1940269 IC50 172.0 nM
COc1cccc(NC(=O)Cc2ccc(Nc3ncnc4cc(OC)c(OC)cc34)cc2)c1 CHEMBL1940260 IC50 175.0 nM
COc1cccc(NC(=O)NCc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)c1 CHEMBL1940262 IC50 177.0 nM
Nc1nccc(Oc2ccc3c(C(=O)Nc4ccc(F)c(C(F)(F)F)c4)cccc3c2)n1 CHEMBL5276611 IC50 177.0 nM
COc1cc2c(Oc3ccc(NC(=O)c4cc5cccnc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 CHEMBL4279457 IC50 183.1 nM
Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 CHEMBL101253 Kd 190.0 nM
COc1cc2c(Oc3ccc(-c4nc5ccccc5s4)cc3F)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL604483 IC50 190.0 nM
COc1cc(O)c2c(c1)-c1cccc(c1)[C@H](O)[C@@H](O)C(=O)CCC[C@H](C)OC2=O CHEMBL4515912 IC50 190.0 nM
OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1986943 pKi 199.53 nM
Cc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL1970074 pKi 199.53 nM
Cc1c[nH]c2nccc(Oc3c(F)cc(Nc4cc(Cl)nc(N)n4)cc3F)c12 CHEMBL1971943 pKi 199.53 nM
COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC CHEMBL1991078 pKi 199.53 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1 CHEMBL1983268 pKi 199.53 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 CHEMBL1967531 pKi 199.53 nM
Cc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)n[nH]c12 CHEMBL1973937 pKi 199.53 nM
CN1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4CC(N)=O)n3)c(F)c2)CC1 CHEMBL3689081 IC50 205.0 nM
COc1cccc(CC(=O)Nc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)c1 CHEMBL1940266 IC50 209.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(F)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593987 IC50 210.0 nM
COc1ccc(Nc2nccc(-c3cn(C)c4ccccc34)n2)cc1OCCOCCn1ccnc1[N+](=O)[O-] CHEMBL5426036 IC50 226.6 nM
NC(=O)C1(c2cccc(CCc3nc(Nc4cnn(C5CCNCC5)c4)ncc3C(F)(F)F)c2)CC1 CHEMBL3916024 IC50 228.0 nM
Nc1cc(Oc2ccc3c(C(=O)Nc4ccc(F)c(C(F)(F)F)c4)cccc3c2)ncn1 CHEMBL5280119 IC50 235.0 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 Kd 240.0 nM
Cc1cc(C2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1 CHEMBL3689080 IC50 240.0 nM
CCC(=O)NCC1CCN(c2ccc(NC(=O)Nc3cccc(Oc4ccnc5cc(OC)c(OC)cc45)c3)cc2C(F)(F)F)CC1 CHEMBL4445808 GI50 240.0 nM
Cc1cccc(NC(=O)Cc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL1964307 pKi 251.19 nM
Nc1n[nH]c2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc12 CHEMBL1997623 pKi 251.19 nM
NC(=O)c1cccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)c1 CHEMBL1982957 pKi 251.19 nM
Nc1ccc(-c2csc3c(C=Cc4nc5ccccc5[nH]4)cnc(N)c23)cc1 CHEMBL1988300 pKi 251.19 nM
Fc1cnc(Nc2ccccc2)nc1Nc1ccccc1 CHEMBL491758 pKi 251.19 nM
CN(c1ncccc1CNc1nc(Nc2ccc3c(c2)CC(=O)N3)ncc1C(F)(F)F)S(C)(=O)=O CHEMBL1084546 pKi 251.19 nM
Clc1cc(-c2c[nH]c3ncccc23)nc(NC2CCCCC2)n1 CHEMBL2006439 pKi 251.19 nM
Nc1c(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ccc2nccnc12 CHEMBL2004438 pKi 251.19 nM
CNC(=O)c1c(N)n(CCOC)c2nc(C#CC(C)(O)COC)ccc2c1=O CHEMBL3644864 IC50 257.0 nM
Cn1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)n1 CHEMBL3912708 IC50 268.0 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1 CHEMBL103667 IC50 270.0 nM
O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1 CHEMBL3301607 IC50 274.0 nM
COc1cc(N2CCNCC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1 CHEMBL3689069 IC50 275.0 nM
COc1cccc(NC(=O)Cn2cc(Oc3ccnc4cc(OC)c(C#N)cc34)cn2)c1 CHEMBL1940114 IC50 282.0 nM
CN1CCN(c2nc(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc3n2)CC1 CHEMBL565612 pKi 316.23 nM
Cc1cc(C)c(C=C2C(=O)Nc3ccccc32)[nH]1 CHEMBL2002702 pKi 316.23 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)c1 CHEMBL185569 pKi 316.23 nM
Cc1n[nH]c2ncc(C#N)c(-c3ccccc3)c12 CHEMBL1965495 pKi 316.23 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12 CHEMBL271381 pKi 316.23 nM
COc1ccc(-c2ccc(NC(=O)Nc3ccc(F)c(C)c3)cc2)c2c(N)noc12 CHEMBL1979093 pKi 316.23 nM
COc1cccc(CNC(=O)c2cc3c(-c4ccccc4)n[nH]c3s2)c1 CHEMBL1987009 pKi 316.23 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3C)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595406 IC50 340.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3F)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL594228 IC50 350.0 nM
COCC/C(=N\S(=O)(=O)Cc1ccc(Cl)cc1)Nc1ccc(Oc2ccnc3cc(OCCCN4CCOCC4)c(OC)cc23)c(F)c1 CHEMBL4799113 IC50 358.0 nM
CNc1nc2[nH]c(-c3cccc(CNC(=O)COC)n3)cc2c2c1ncn2C CHEMBL1923983 IC50 360.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(C)c34)cc2)c1 CHEMBL4103605 IC50 376.0 nM
COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1 CHEMBL1908396 Kd 390.0 nM
COc1ccc2c(c1)C(=Cc1c[nH]cn1)C(=O)N2 CHEMBL2002649 pKi 398.11 nM
O=C(Nc1cccc(C(F)(F)F)n1)Nc1ccnc2c(F)cccc12 CHEMBL1966816 pKi 398.11 nM
O=C(NCc1ccc(Cl)cc1)c1cc2c(-c3ccccc3)n[nH]c2s1 CHEMBL1967094 pKi 398.11 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]ncc34)cc2)c1 CHEMBL375284 pKi 398.11 nM
Cn1cc(C=C2C(=O)Nc3cccnc32)c2ccccc21 CHEMBL1516890 pKi 398.11 nM
O=c1[nH]c2cnc(-n3cnc4ccc(F)cc43)nc2n1C1CCOc2c(F)cccc21 CHEMBL2000393 pKi 398.11 nM
O=C(NN=Cc1ccc(O)cc1O)Nc1cccc2nsnc12 CHEMBL1999811 pKi 398.11 nM
CCCCOc1ncnc2[nH]cc(-c3ccccc3)c12 CHEMBL1996817 pKi 398.11 nM
COc1cc(C=C(C#N)c2nc3cc(C)ccc3[nH]2)c(Br)cc1O CHEMBL2000345 pKi 398.11 nM
O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccccc2N1 CHEMBL296586 pKi 398.11 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL231209 pKi 398.11 nM
Cc1cc(OCC2CCC(C(=O)O)C2)c(NC(=O)Nc2cnc(C#N)cn2)cc1Cl CHEMBL1991285 pKi 398.11 nM
C=CC(=O)N1CCN(CCCn2c(=O)c(-c3c(Cl)c(OC)cc(OC)c3Cl)cc3cnc(NC)nc32)CC1 CHEMBL4068509 IC50 410.0 nM
O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1)c1ccccc1 CHEMBL2380845 IC50 417.0 nM
O=C(Nc1ccc(Nc2ncnc3sc4c(c23)CCCC4)cc1)Nc1cccc(Br)c1 CHEMBL3628799 IC50 420.0 nM
Nc1nccc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)n1 CHEMBL4104297 IC50 420.0 nM
O=C(c1cccc(CNc2n[nH]c3cccc(Cl)c23)c1)N1CCN(C(=O)c2ccc(Cl)cc2Cl)CC1 CHEMBL5393904 IC50 423.2 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C#N)cc(S(F)(F)(F)(F)F)c1 CHEMBL3907057 IC50 440.0 nM
COc1cc2ncnc(Nc3cnn(CC(=O)Nc4ccc(N(C)C)cn4)c3)c2cc1OC CHEMBL1940106 IC50 453.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(Cl)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593274 IC50 470.0 nM
COc1cc2ncnc(Nc3ccc(CC(=O)Nc4cnn(C(C)C)c4)cc3)c2cc1OC CHEMBL1940275 IC50 485.0 nM
CN(c1ccc(C2CCNCC2)nc1)c1ncc(C(F)(F)F)c(CCc2ccccc2C(N)C(N)=O)n1 CHEMBL3918715 IC50 492.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1-c1nc2c(C(N)=O)cccc2[nH]1 CHEMBL5437375 IC50 499.0 nM
COc1cc2c(Oc3ccc(NC(=O)Nc4ccnn4C)c(Cl)c3)ncnc2cc1OCCCN1CCCC1 CHEMBL5397253 IC50 501.0 nM
O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21 CHEMBL1997129 pKi 501.19 nM
CCc1nc(-c2cccc(C)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 CHEMBL363648 pKi 501.19 nM
Oc1cccc(Nc2ncnc3scc(Cl)c23)c1 CHEMBL1982992 pKi 501.19 nM
Nc1ncnc2sc(Br)c(-c3ccc(NC(=O)Cc4cccc(Cl)c4)cc3)c12 CHEMBL1980896 pKi 501.19 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 CHEMBL219722 pKi 501.19 nM
O=C(O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2F)=NC3)cc1 CHEMBL259084 pKi 501.19 nM
O=C(NCC1CCCCC1)c1cc2c(-c3ccccc3)n[nH]c2s1 CHEMBL2005475 pKi 501.19 nM
CCS(=O)(=O)c1ccc(-c2cncc3sc(C(N)=O)cc23)cc1 CHEMBL2000104 pKi 501.19 nM
CC(NC(=O)c1ccc(-c2ccncc2)cc1)c1ccccc1 CHEMBL1999428 pKi 501.19 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(O)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL606466 IC50 520.0 nM
COc1cc(C2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1 CHEMBL3689071 IC50 538.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)C(OC(=O)c4ccc(F)cc4)C(C)(C)C)cc3F)c2cc1OC CHEMBL4779315 IC50 540.0 nM
O=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)[C@H]1CCCN1 CHEMBL2208034 IC50 554.5 nM
COc1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094408 IC50 587.0 nM
Cn1cc(-c2ccc(F)cc2)c(=O)c2c(Nc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)c(F)c3)nccc21 CHEMBL4584949 IC50 591.0 nM
CN1CCN(c2ccc(-c3cnc4ccccc4c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3799275 IC50 600.0 nM
Cc1c(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc2n1C1CC(CN2CCCC2)C1 CHEMBL1968791 pKi 630.96 nM
Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1964687 pKi 630.96 nM
Cc1ccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)cc1 CHEMBL2005828 pKi 630.96 nM
Cc1ccc(-c2nn(C(C)(C)C)c3ncnc(N)c23)cc1 CHEMBL306380 pKi 630.96 nM
Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2C1CCC(N2CCCC2)CC1 CHEMBL1965910 pKi 630.96 nM
NC(=O)c1ccc(-c2c[nH]c3nccc(Cl)c23)cc1 CHEMBL1982711 pKi 630.96 nM
O=C(Nc1cnccn1)Nc1ccnc2cc(C(F)(F)F)ccc12 CHEMBL2003817 pKi 630.96 nM
CO[C@H]1CC[C@H](N2C(=O)CNc3ncc(-c4ccc(C(C)(C)O)nc4)nc32)CC1 CHEMBL3586404 IC50 651.0 nM
COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cnn(C)c4)cc3)c2cc1OC CHEMBL1940271 IC50 667.0 nM
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL608533 Kd 670.0 nM
Clc1ccc(CNc2ccnc3oc4ccccc4c23)cc1 CHEMBL1290177 Ki 680.0 nM
CC(C)(C)c1nc2c3ccc(F)cc3c3c(=O)[nH]ccc3c2[nH]1 CHEMBL21156 IC50 690.0 nM
CN(C)CC(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1 CHEMBL1908395 Kd 700.0 nM
COc1cc(O)c2c(c1)CCCCCC(=O)/C=C/C[C@H](C)OC2=O CHEMBL1668419 IC50 720.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 740.0 nM
O=C(NCCCNc1cc(-c2cn(-c3ccccc3)nc2-c2cccc(O)c2)ccn1)Nc1ccc(F)cc1 CHEMBL5191468 IC50 791.0 nM
CNC(=O)c1cc2c(-c3ccccc3F)n[nH]c2s1 CHEMBL1977681 pKi 794.33 nM
CCc1nc2c(c3cc(OC)c(OC)cc13)C(=O)NC2=O CHEMBL2003524 pKi 794.33 nM
C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 CHEMBL553 pKi 794.33 nM
N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCCN4CCOCC4)cc2-3)cn1 CHEMBL398951 pKi 794.33 nM
COc1ccc(-c2cnc3c(Br)cnn3c2)cc1 CHEMBL443962 pKi 794.33 nM
COc1ccc(-c2ccc(NC(=O)Nc3cc(F)cc(F)c3)cc2)c2c(N)noc12 CHEMBL1969190 pKi 794.33 nM
COc1cc(C=C(C#N)c2nc3ccccc3[nH]2)c(Br)cc1O CHEMBL1994241 pKi 794.33 nM
Cc1c(C=O)c(O)n2c(nc3ccccc32)c1C#N CHEMBL1989856 pKi 794.33 nM
Cc1cc(C)c2oc(Nc3ccc(-c4cccc(C(N)=O)c4N)cc3F)nc2c1 CHEMBL1990884 pKi 794.33 nM
Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCC(=O)O CHEMBL2007064 pKi 794.33 nM
NC(=O)c1cc2c(-c3ccc(F)cc3F)cncc2s1 CHEMBL1975787 pKi 794.33 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccccc4C(F)(F)F)cc3)c12 CHEMBL1987910 pKi 794.33 nM
COc1cc2c(Nc3ccc(-c4nc5ccc(F)cc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL604992 IC50 865.0 nM
O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1)c1ccc(F)cc1C(F)(F)F CHEMBL2380834 IC50 867.0 nM
CNC(=O)c1nn(C)c2c1C(C)(C)Cc1cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc1-2 CHEMBL564829 IC50 920.0 nM
Cc1cccc(-c2[nH]c(Cc3cccc(C(N)=O)c3)nc2-c2ccc3ncccc3c2)n1 CHEMBL1164957 IC50 940.0 nM
COc1ccc(-c2ccc(Cn3cc(CCN)c4cc(OCCc5ccc(O)cc5)ccc43)cc2)cc1 CHEMBL1094196 IC50 960.0 nM
N#CCCc1ccc2c(c1)-c1[nH]c3ccc([N+](=O)[O-])cc3c1CC(=O)N2 CHEMBL260138 Log IC50 1000.0 nM
O=C(NC(=S)Nc1ccc(O)c(-c2nc3ccccc3s2)c1)c1ccc([N+](=O)[O-])cc1 CHEMBL460746 IC50 1000.0 nM
COCCNc1nccc(-c2c(-c3ccc(F)cc3)nc3cnccn23)n1 CHEMBL1969372 pKi 1000.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3ccc4nccnc4c3N)cc2)c1 CHEMBL507936 pKi 1000.0 nM
CN(C)c1ccc(CNC(=O)c2cc3c(-c4ccccc4)n[nH]c3s2)cc1 CHEMBL1984367 pKi 1000.0 nM
COc1cc2cnc3c(c2cc1OC)C(=O)NC3=O CHEMBL1982506 pKi 1000.0 nM
S=c1[nH]nc2c3c4c(sc3n3c(=S)[nH]nc3n12)CCC4 CHEMBL1969537 pKi 1000.0 nM
NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(-c3ccncc3)ccc2c1=O CHEMBL340384 pKi 1000.0 nM
NCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL592030 pKi 1000.0 nM
Cc1ccc2nccc(NC(=O)Nc3cccc(C(F)(F)F)n3)c2c1 CHEMBL1964444 pKi 1000.0 nM
CN1CCN(c2ccc(-c3cnc4c(c3)N(Cc3c(F)ccc(F)c3Cl)CCN4)cn2)CC1 CHEMBL1164265 pKi 1000.0 nM
NC(=O)c1cc2c(-c3cccc(F)c3)cncc2s1 CHEMBL1971017 pKi 1000.0 nM
COc1cc(C=O)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 CHEMBL207995 pKi 1000.0 nM
CN1CCC(NC(=O)c2cc3c(-c4ccccc4)n[nH]c3s2)CC1 CHEMBL1987007 pKi 1000.0 nM
Clc1cc(NC2CCCCC2)nc(-c2c[nH]c3ncccc23)n1 CHEMBL1997846 pKi 1000.0 nM
COc1cc(C=C(C#N)c2n[nH]c(N)c2C#N)ccc1O CHEMBL2002407 pKi 1000.0 nM
Cc1ccc(Nc2nc3ccc([N+](=O)[O-])cc3[nH]2)nc1 CHEMBL1992937 pKi 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM