COc1cc(F)c([C@@H]2CN3CCON=C3[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL5271637 EC50 0.02 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)c(O)c2)c(F)c1 CHEMBL4776349 EC50 0.05 nM
O=C(NCCCCN1CCCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730217 EC50 0.07 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)c(O)c2)c(F)c1 CHEMBL4790836 EC50 0.078 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)cc1 CHEMBL4743917 EC50 0.085 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(O)c2)c(F)c1 CHEMBL4755590 EC50 0.087 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4744094 EC50 0.092 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728769 EC50 0.1 nM
CCCCC[C@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C CHEMBL4440913 IC50 0.1 nM
COc1ccc([C@@H]2CCNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4784400 EC50 0.11 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cc2)c(F)c1 CHEMBL4758920 EC50 0.11 nM
NC[C@H]1CC[C@@H](NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3729012 EC50 0.13 nM
CCN1C[C@@H](c2ccc(OC)cc2)[C@H](NC(=O)Nc2ccc(F)cc2)C1=O CHEMBL5288361 EC50 0.13 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4781596 EC50 0.14 nM
CS(=O)(=O)Nc1ccccc1-c1ccc(N2CCC[C@@H](NC(=O)Nc3ccc(Cl)cc3)C2=O)cc1 CHEMBL5284349 EC50 0.14 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)cc1F CHEMBL4744835 EC50 0.15 nM
NCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727613 EC50 0.16 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(F)c2)c(F)c1 CHEMBL4762030 EC50 0.16 nM
COc1ccc(C[C@H](NC(=O)Nc2ccc(Cl)cc2)c2noc(CCO)n2)cc1 CHEMBL5281870 EC50 0.17 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Br)cc2)c(F)c1 CHEMBL4761554 EC50 0.19 nM
O=C(NC1CCNCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728932 EC50 0.2 nM
CS(=O)(=O)NCC1(c2ccc(N3CCC[C@@H](NC(=O)Nc4ccc(C(F)(F)F)cc4)C3=O)cc2)CC1 CHEMBL5270733 EC50 0.21 nM
CC(C)CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729214 EC50 0.24 nM
COc1ccc([C@@H]2COC[C@@H]2NC(=O)Nc2ccc(F)cc2)cc1 CHEMBL4794375 EC50 0.25 nM
COc1ccc(C[C@H](NC(=O)Nc2ccc(Cl)cc2)c2nnn(CCO)n2)cc1 CHEMBL5287715 EC50 0.25 nM
COc1ccc(NC(=O)N[C@@H]2/C(=N/OCCO)NC[C@H]2c2c(F)cc(OC)cc2F)cc1 CHEMBL5273168 EC50 0.27 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 CHEMBL4760897 EC50 0.29 nM
COc1ccc([C@@H]2CN3C(=O)CON=C3[C@H]2NC(=O)Nc2ccc(F)cc2)cc1 CHEMBL5275581 EC50 0.29 nM
O=C(NCCCCN1CCC[C@H]1F)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730056 EC50 0.3 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cc(C)ns2)c(F)c1 CHEMBL4778725 EC50 0.32 nM
NCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730438 EC50 0.34 nM
O=C(NCCCCN1CCC[C@@H]1F)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730133 EC50 0.35 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731671 EC50 0.35 nM
COc1cnc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4753713 EC50 0.36 nM
O=C(NCCCCN1CCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729434 EC50 0.4 nM
CN(C)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732621 EC50 0.41 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 CHEMBL4784510 EC50 0.41 nM
O=C(NCC1CCCNC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731259 EC50 0.45 nM
NCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731107 EC50 0.45 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4745044 EC50 0.45 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730874 EC50 0.46 nM
CP(C)(=O)c1ccccc1-c1ccc(N2CC3(CC3)[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F CHEMBL5288386 EC50 0.48 nM
NCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3727601 EC50 0.5 nM
CCCCC[C@@H](O)c1nc(-c2ccccc2)n(-c2ccccc2)c1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC CHEMBL4574711 IC50 0.5 nM
O=C(NCCCCN1CCOCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728644 EC50 0.53 nM
NCc1cccc(CNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)c1 CHEMBL3731166 EC50 0.55 nM
CCc1ccc(C[C@H](NC(=O)Nc2ccc(Cl)cc2)/C(N)=N/OCCO)cc1 CHEMBL5274399 EC50 0.56 nM
NCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728245 EC50 0.61 nM
CCc1ccc(C[C@H](NC(=O)Nc2ccc(Cl)cc2)c2noc(N(C)CCO)n2)cc1 CHEMBL5270974 EC50 0.63 nM
O=C(NCCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729460 EC50 0.66 nM
N/C(=N\C(=O)CCO)[C@H](Cc1ccc(Cl)cc1)NC(=O)Nc1ccc(Cl)cc1 CHEMBL5286212 EC50 0.66 nM
CN(C)CCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732081 EC50 0.7 nM
CCCCC[C@H](O)c1nc(-c2ccccc2)n(-c2ccccc2)c1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC CHEMBL4462922 IC50 0.7 nM
CS(=O)(=O)NCC1(c2ccc(N3CCC[C@@H](NC(=O)Nc4cnc(Cl)cn4)C3=O)cc2)CCC1 CHEMBL5280720 EC50 0.7 nM
O=C(NCCOCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730159 EC50 0.72 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cc3ccccc3s2)c(F)c1 CHEMBL4749577 EC50 0.76 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C#N)cc2)c(F)c1 CHEMBL4742149 EC50 0.78 nM
CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(=O)O CHEMBL4785302 EC50 0.78 nM
O=C(NCC1CCNCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731113 EC50 0.82 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)cc2)c(F)c1 CHEMBL4763673 EC50 0.86 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)c(F)c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732902 EC50 0.87 nM
CN1CCCN(CCCCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3731635 EC50 0.89 nM
CCC[C@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C CHEMBL4436717 IC50 0.9 nM
COc1ccc(C2CNC(=O)C2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4740375 EC50 0.9 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)cc1F CHEMBL4751168 EC50 0.9 nM
COc1ccc([C@@H]2CNC(=O)[C@@H]2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4793814 EC50 0.91 nM
O=C(NC1CCNC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729013 EC50 0.94 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cccc(F)c2)c(F)c1 CHEMBL4763824 EC50 0.95 nM
CC(C)(CN)CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729228 EC50 0.98 nM
CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](CCSC)C(N)=O)C(C)C CHEMBL552527 EC50 1.0 nM
CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NC(C)(C)C(=O)O CHEMBL2408793 EC50 1.0 nM
O=C(NCCCO)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731461 EC50 1.0 nM
CCN(CC)CCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729246 EC50 1.0 nM
CCCCC[C@@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C CHEMBL4536276 IC50 1.0 nM
COc1cc(F)c([C@H]2CCN(CCC(F)F)C[C@@H]2NC(=O)Nc2ccc(Cl)cc2)c(F)c1 CHEMBL5286200 EC50 1.0 nM
COc1ccc([C@H]2CCN(c3ccnnc3)C[C@@H]2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL5290016 EC50 1.0 nM
COc1ccc([C@@H]2CCN(Cc3ccccn3)C(=O)[C@@H]2NC(=O)Nc2ccc(F)cc2)cc1 CHEMBL5275766 EC50 1.0 nM
COc1ccc([C@H]2CCN(Cc3cccnc3)C(=O)[C@@H]2NC(=O)Nc2ccc(F)cc2)cc1 CHEMBL5278464 EC50 1.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731849 EC50 1.1 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)nc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731163 EC50 1.1 nM
CC(C)(C)OC(=O)N1CCC(NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)C1 CHEMBL3730197 EC50 1.2 nM
CN1CCN(CCCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3CC[C@H]2C32CC2)CC1 CHEMBL3732566 EC50 1.3 nM
O=C(NC1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729500 EC50 1.3 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731889 EC50 1.3 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)nc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730330 EC50 1.3 nM
NCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732404 EC50 1.4 nM
COCC1CCCN1CCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728573 EC50 1.4 nM
CNc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4781488 EC50 1.4 nM
O=C(NCC1CCCO1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729487 EC50 1.5 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Cl)nc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727408 EC50 1.6 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(C)c1 CHEMBL4743084 EC50 1.6 nM
CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O CHEMBL392438 IC50 1.7 nM
O=C(NCCCO)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728559 EC50 1.8 nM
CCOCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733012 EC50 1.8 nM
CC(CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)N1CCCC1 CHEMBL3731167 EC50 1.8 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ncc(Cl)s2)c(F)c1 CHEMBL4790245 EC50 1.9 nM
N#Cc1ccc(NC(=O)N[C@@H]2C(=O)NC[C@H]2c2cc3c(cc2F)OCC3)cc1 CHEMBL5282261 EC50 1.92 nM
COc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cc1 CHEMBL3728297 EC50 2.0 nM
O=C(NCC1CCCN1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733084 EC50 2.0 nM
O=C(N[C@H]1CC[C@@H](CN2CCCC2)CC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729758 EC50 2.1 nM
O=C(NCC1CCCCN1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729130 EC50 2.1 nM
CC1CCC(C)N1CCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728238 EC50 2.1 nM
CC(C)C[C@H](NC(=O)Nc1ccc(C(F)(F)F)cc1)C(=O)NC(C)(C)C(=O)O CHEMBL2408792 EC50 2.3 nM
CCN1CCN(CCCCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3731035 EC50 2.3 nM
O=C(NCCN1CCNC1=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732225 EC50 2.4 nM
O=C(NCC(F)(F)F)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729752 EC50 2.4 nM
Cc1cccc(-c2oc(C)nc2C(=O)Cc2cnn(Cc3nc(C(C)(F)F)co3)n2)c1 CHEMBL5274258 EC50 2.4 nM
CCCCC[C@H](O)c1nc(-c2ccccc2)oc1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C CHEMBL4434857 IC50 2.5 nM
O=C(Nc1ccc(F)cc1)N[C@@H]1c2nnnn2C[C@H]1c1cc2c(cc1F)OCC2 CHEMBL5288663 EC50 2.5 nM
O=C(N[C@@H]1CC[C@@H](CN2CCCC2)OC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729306 EC50 2.7 nM
O=C(NCCF)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731469 EC50 2.7 nM
CNCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730502 EC50 2.8 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cn2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729170 EC50 2.9 nM
O=C(Nc1ccc(Br)nc1)C1C(C(=O)NC2CCNCC2)C2CCC1C21CC1 CHEMBL4747556 EC50 2.9 nM
CP(C)(=O)c1ccccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3csc(Cl)c3)C2=O)c(F)c1F CHEMBL5276954 EC50 2.9 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N[C@@H]1CCCN(c2ccc(N3CCCCC3)cc2)C1=O CHEMBL5287909 EC50 3.0 nM
O=C(Nc1ccc(F)cc1)N[C@@H]1C(=O)NC[C@H]1c1ccc(Cl)cc1F CHEMBL4793557 EC50 3.1 nM
CNC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730852 EC50 3.2 nM
O=C(NCC1CCCO1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730354 EC50 3.2 nM
COc1ccc(NC(=O)N[C@@H]2C(=O)NC[C@H]2c2c(F)cc(OC)cc2F)cc1 CHEMBL4789579 EC50 3.2 nM
O=C(NCC1CCC(O)CC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728753 EC50 3.3 nM
CN(C)C(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727840 EC50 3.4 nM
CCC[C@@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C CHEMBL4551559 IC50 3.4 nM
CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(=O)O CHEMBL5285150 EC50 3.57 nM
COc1ccc(CC(NC(=O)Nc2ccc(Cl)cc2)C(N)=O)cc1 CHEMBL4796468 EC50 3.6 nM
CCSCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730279 EC50 3.7 nM
COC(=O)CCC[C@H](O)[C@H](O)/C=C/c1nc(C)n(C)c1[C@@H](C)O CHEMBL4534051 IC50 3.8 nM
CC(C)CNC(=O)[C@H]1[C@H](C(=O)NCc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728562 EC50 3.9 nM
CCN(CC)CCCC(C)NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732049 EC50 3.9 nM
O=C(Nc1ccc(Br)cc1)N[C@@H](Cc1ccccc1)C(=O)NN1CCCCNC1=O CHEMBL3588929 EC50 4.0 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(Cl)c1 CHEMBL4743133 EC50 4.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3ccc(F)cc32)cc1 CHEMBL5207056 IC50 4.0 nM
CN1CCN(CCCCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3728649 EC50 4.1 nM
O=C(NCCCn1ccnc1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731739 EC50 4.1 nM
COc1ccc(C[C@H](CO)NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL5282051 EC50 4.12 nM
CC(C)(C)OC(=O)NCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732493 EC50 4.2 nM
O=C(NC1CCCNC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730024 EC50 4.2 nM
O=C(NCCCCN1CCC(F)(F)C1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729299 EC50 4.4 nM
CC(CO)NCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728401 EC50 4.5 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cn2)c(F)c1 CHEMBL4792002 EC50 4.5 nM
COCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728536 EC50 4.8 nM
O=C(NCCN1CCNC1=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730629 EC50 4.8 nM
O=C(NCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731297 EC50 4.9 nM
COCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731396 EC50 5.0 nM
O=C(NCCC(F)CN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732090 EC50 5.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N[C@@H]1CCCN(c2ccc(-c3ccccc3C(=O)O)cc2)C1=O CHEMBL5282707 EC50 5.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(C(F)(F)F)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731308 EC50 5.4 nM
O=C(NCCCc1nc2ccccc2[nH]1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732803 EC50 5.4 nM
O=C(NCC1CCNCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730960 EC50 5.7 nM
CN1CCCC1CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729542 EC50 5.8 nM
CCc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4783963 EC50 5.8 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)nc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731817 EC50 5.9 nM
O=C(NCCCC(=O)N1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728739 EC50 6.1 nM
COCCN(CCOC)C(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727426 EC50 6.1 nM
O=C(NCCO)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727812 EC50 6.1 nM
NCC1CCN(C(=O)[C@H]2[C@H](C(=O)Nc3ncc(Br)s3)[C@@H]3CC[C@H]2C32CC2)CC1 CHEMBL3728521 EC50 6.2 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729552 EC50 6.4 nM
NC(=O)CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732419 EC50 6.5 nM
CCCCC[C@@H](O)c1nc(-c2ccccc2)oc1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C CHEMBL4582724 IC50 6.5 nM
N#CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727442 EC50 6.7 nM
COc1ccc(CC(CO)NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4760555 EC50 6.8 nM
CCOC(=O)C1CCCN(C(=O)[C@H](Cc2ccccc2)NC(=O)Nc2ccc(Br)cc2)C1 CHEMBL3590206 EC50 7.0 nM
O=C(NCCCn1cccn1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727798 EC50 7.1 nM
NC(=O)CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729822 EC50 7.3 nM
O=C(NCC1CCNCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3733130 EC50 7.3 nM
NCc1ccc(CNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)cc1 CHEMBL3727801 EC50 7.5 nM
CCN(CC)CCN(CC)C(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729293 EC50 7.6 nM
Cc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C4(O)CC4)co3)n2)c1 CHEMBL3915698 EC50 7.6 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2cnc(Br)cn2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730451 EC50 7.9 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)nc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732086 EC50 7.9 nM
CC(C)(O)c1coc(Cn2ncc(NC(=O)c3ncoc3-c3ccccc3)n2)n1 CHEMBL3984386 EC50 8.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(C2CCN(c3ncccn3)CC2)C1=O CHEMBL5093348 EC50 8.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730856 EC50 8.1 nM
CN(C)CCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730991 EC50 8.2 nM
Cc1nc(CCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3CC[C@H]2C32CC2)[nH]c1C CHEMBL3727697 EC50 8.3 nM
O=C(NCC1CCCN1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729189 EC50 8.3 nM
O=C(NC1CCNC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731273 EC50 8.9 nM
O=C(NCCCn1ccnc1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732253 EC50 9.0 nM
O=C(NC1CCCNC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732729 EC50 9.1 nM
O=C(NCCN1CCNC1=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730714 EC50 9.1 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2c(F)cc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732403 EC50 9.4 nM
CN1CCN(CCCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3729352 EC50 9.5 nM
O=C(NCC1COCCO1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731632 EC50 9.5 nM
CN(C)CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729034 EC50 9.6 nM
O=C(NCCCCO)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731406 EC50 9.6 nM
N#Cc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4758129 EC50 9.7 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc3scnc3c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728025 EC50 10.0 nM
NCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729988 EC50 10.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4077102 IC50 10.0 nM
CC(=O)c1coc(Cn2ccc(NC(=O)c3ncoc3-c3ccccc3)n2)n1 CHEMBL4755656 EC50 10.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2cc(-c3ccc(Cl)cc3)on2)c(F)c1 CHEMBL5191583 EC50 10.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3ccccc32)cc1 CHEMBL5195186 IC50 10.0 nM
Cc1cccc(C2(NC(=O)N[C@@H]3C(=O)NC[C@H]3c3c(F)cc(Br)cc3F)CC2)n1 CHEMBL5265888 EC50 10.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N[C@@H]1CCCN(c2ccc(N3CC4(COC4)C3)cc2)C1=O CHEMBL5273483 EC50 10.0 nM
CN1CCN(c2ccc(N3CCC[C@@H](NC(=O)Nc4ccc(C(F)(F)F)cc4)C3=O)cc2)CC1 CHEMBL5270218 EC50 10.0 nM
Cn1c(C(C)(C)C)c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n1-c1ccccc1 CHEMBL377226 EC50 10.0 nM
Cc1nc(C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c(-c2cccc(Cl)c2)o1 CHEMBL3981311 EC50 10.1 nM
Cc1nc(C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c(-c2ccccc2)o1 CHEMBL3954589 EC50 10.3 nM
CC(C)(C)OC(=O)NCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731311 EC50 11.0 nM
CN(C)CCN(C)C(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730777 EC50 11.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(C(F)(F)F)nc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730922 EC50 11.0 nM
O=C(NCCOCCO)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729977 EC50 11.0 nM
Cc1cccc(-c2ocnc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 CHEMBL3984964 EC50 11.3 nM
Cc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 CHEMBL3976318 EC50 11.8 nM
O=C(NCCn1cncn1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732504 EC50 12.0 nM
O=C(NCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731600 EC50 12.0 nM
CN(CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)C(=O)OC(C)(C)C CHEMBL3730902 EC50 12.0 nM
CC(C)(CN)CNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729617 EC50 12.0 nM
COc1ccc([C@@H]2NC(=O)[C@@H]2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4778312 EC50 12.0 nM
N#Cc1ccc(C[C@@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCCc3ccccc32)cc1 CHEMBL5190571 IC50 12.0 nM
CP(C)(=O)c1ccccc1-c1ccc(N2CC(CO)[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F CHEMBL5267353 EC50 12.0 nM
COc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 CHEMBL3932747 EC50 12.7 nM
Cc1cc(C)n(CCC(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)n1 CHEMBL3727417 EC50 13.0 nM
O=C(NCc1ccoc1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727544 EC50 13.0 nM
NC[C@H]1CC[C@H](NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3730760 EC50 13.0 nM
CNCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3733217 EC50 13.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730919 EC50 13.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729082 EC50 13.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4066521 IC50 13.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCCc3ccccc32)cc1 CHEMBL5187135 IC50 13.0 nM
COc1ccc(Cc2c(C)c(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)cc1 CHEMBL5284145 EC50 13.0 nM
Cc1nc(C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c(-c2cccc(F)c2)o1 CHEMBL3981821 EC50 13.2 nM
CNCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731053 EC50 14.0 nM
CCOc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 CHEMBL4756320 EC50 14.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731133 EC50 15.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4081147 IC50 15.0 nM
O=C(NCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729242 EC50 16.0 nM
CCN1CCCC1CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728012 EC50 16.0 nM
COCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732748 EC50 16.0 nM
CC(C)(C)OC(=O)NCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728451 EC50 17.0 nM
O=C(NC1CCNCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730548 EC50 17.0 nM
O=C(Nc1ccc(Cl)cn1)N[C@@H]1CCCN(c2ccc(C3(CN4CCOCC4)CC3)cc2)C1=O CHEMBL5265951 EC50 17.0 nM
CS(=O)(=O)NCC1(c2ccc(N3C[C@@H](O)C[C@@H](NC(=O)Nc4ncc(Cl)cc4F)C3=O)cc2)CC1 CHEMBL5273627 EC50 17.0 nM
COc1cc(-c2ccccc2NS(C)(=O)=O)ccc1N1CCC[C@@H](NC(=O)Nc2ncc(C(F)(F)F)cc2F)C1=O CHEMBL5284802 EC50 17.0 nM
COc1cccc(-c2ocnc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 CHEMBL3983228 EC50 17.2 nM
CC(C)(O)c1coc(Cn2ncc(NC(=O)c3ncoc3-c3cccc(Cl)c3)n2)n1 CHEMBL3938248 EC50 17.8 nM
CC(C)(C)OC(=O)N1CCCC(NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)C1 CHEMBL3728062 EC50 18.0 nM
O=C(NCCCn1cncn1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730013 EC50 18.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4090485 IC50 18.0 nM
Cc1nc(CCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)[nH]c1C CHEMBL3731599 EC50 19.0 nM
NCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3729077 EC50 19.0 nM
NCC1CCN(C(=O)[C@H]2[C@H](C(=O)Nc3ncc(Br)s3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3727924 EC50 19.0 nM
CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(=O)O CHEMBL4454321 EC50 19.0 nM
CC(C)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728852 EC50 20.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)Nc1cccnc1)C1CCCC1 CHEMBL4762142 EC50 20.0 nM
CC(=O)c1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3CC[C@@H]2C32CC2)o1 CHEMBL3727620 EC50 21.0 nM
CC(C)C[C@@H](CO)NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730283 EC50 21.0 nM
Cc1nc(C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c(-c2cccc(C(F)(F)F)c2)o1 CHEMBL3960228 EC50 21.7 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3727795 EC50 22.0 nM
COC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732895 EC50 22.0 nM
NCCCCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729885 EC50 22.0 nM
Cc1cnc(NC(=O)N[C@@H]2CCCN(c3ccc(-c4ccccc4NS(C)(=O)=O)cc3F)C2=O)cn1 CHEMBL5278986 EC50 22.0 nM
CC(=O)c1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cc1 CHEMBL3728508 EC50 23.0 nM
NS(=O)(=O)c1ccc(CCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)cc1 CHEMBL3733264 EC50 23.0 nM
O=C(NC1CCNCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728546 EC50 23.0 nM
COc1ccc(CC(C)NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4782531 EC50 23.0 nM
CCn1nc(CCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)cc1C CHEMBL3730881 EC50 24.0 nM
O=C(NC1CCNCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732094 EC50 24.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Cl)nc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728771 EC50 24.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4062611 IC50 24.0 nM
CC(C)C(C(=O)O)C(C)NC(=O)Nc1ccc(Br)cc1 CHEMBL5284816 EC50 25.0 nM
CP(C)(=O)c1ccccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3)C2=O)c(F)c1F CHEMBL5284060 EC50 25.0 nM
C[C@H](NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)C(N)=O CHEMBL3733280 EC50 26.0 nM
CC(C)(CN)CNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728857 EC50 26.0 nM
CC(C)(C)OC(=O)NCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731561 EC50 27.0 nM
COC(=O)CCC[C@H](O)[C@H](O)/C=C/c1nc(C)n(C)c1[C@H](C)O CHEMBL4460558 IC50 27.8 nM
CC(=O)c1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)o1 CHEMBL3732960 EC50 28.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2c(F)cc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729342 EC50 28.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4082093 IC50 28.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(Cl)cc3)o2)c(F)c1 CHEMBL5190385 IC50 28.0 nM
CSc1ccc(NC(=O)Nc2c(C(C)C)n(C)n(-c3cnc4ccccc4c3)c2=O)cc1 CHEMBL379762 EC50 30.0 nM
Cc1c(NC(=O)Nc2ccc(I)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL208884 EC50 30.0 nM
NCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3733340 EC50 30.0 nM
CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)Nc1cccnc1 CHEMBL4742937 EC50 30.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3ccccc3C2)cc1 CHEMBL5196551 IC50 30.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Cl)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728125 EC50 31.0 nM
O=C(NCCC(=O)N1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730211 EC50 31.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Cl)nc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732192 EC50 31.0 nM
COc1ccc(CC(NC(=O)Nc2ccc(Cl)cc2)C(=O)O)cc1 CHEMBL4765025 EC50 31.0 nM
COc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCC(N)=O)[C@H]3C=C[C@@H]2C32CC2)cc1 CHEMBL3728506 EC50 32.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729722 EC50 32.0 nM
Cc1nc(C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c(-c2cccc(OC(F)(F)F)c2)o1 CHEMBL3906325 EC50 32.3 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2csc(Br)c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733287 EC50 33.0 nM
CCc1nc2ccccc2n1[C@@H]1CCN(C(=O)c2cc3cc(OC)ccc3[nH]2)C1 CHEMBL249132 EC50 34.0 nM
CCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730944 EC50 34.0 nM
CCN(CC)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730231 EC50 34.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4062488 IC50 34.0 nM
COc1ccc([C@H]2CNC(=O)[C@@H]2NC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL4793603 EC50 34.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)NC2(c3ccc4cc(OC)ccc4c3)CC2)c(F)c1 CHEMBL5277178 EC50 34.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4072333 IC50 35.0 nM
O=C(NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)c1cnoc1-c1ccccc1 CHEMBL3729471 EC50 37.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(Cl)cc3)s2)c(F)c1 CHEMBL5201495 EC50 37.0 nM
CC(=O)N1CCN(CCCCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3729805 EC50 38.0 nM
O=C(Nc1ccc(Cl)cc1F)N[C@@H]1CCN(c2ccc(-c3cnn(C(F)F)c3)c(F)c2F)C1=O CHEMBL5288141 EC50 39.0 nM
O=C(Nc1ccc(Br)cc1)N[C@@H](Cc1ccccc1)C(=O)N1CCCCC1 CHEMBL3588926 EC50 40.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)c(F)c2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732345 EC50 40.0 nM
Cc1cc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)no1 CHEMBL3730873 EC50 40.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2c2nc3cc(Cl)cnc3[nH]2)c(F)c1 CHEMBL5185842 EC50 40.0 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(Cl)cc3)o2)c(F)c1 CHEMBL5181627 EC50 40.0 nM
NC(=O)c1ccccc1-c1ccc(N2CCCC(NC(=O)Nc3ccc(C(F)(F)F)cc3)C2=O)cc1 CHEMBL5271664 EC50 40.0 nM
NC(=O)c1ccccc1-c1ccc(N2CCC[C@H](NC(=O)Nc3ccc(C(F)(F)F)cc3)C2=O)cc1 CHEMBL5287828 EC50 40.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N[C@H]1CCCN(c2ccc(-c3ccccc3F)cc2)C1=O CHEMBL5278412 EC50 40.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N[C@H]1CCCN(c2ccc(-c3ccccc3C(=O)O)cc2)C1=O CHEMBL5270967 EC50 40.0 nM
O=C(Nc1ccccc1F)N[C@@H]1CCCN(c2ccc(-c3ccccc3F)cc2)C1=O CHEMBL5277119 EC50 40.0 nM
CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL379761 pEC50 40.74 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4073052 IC50 41.0 nM
CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1 CHEMBL3588930 IC50 41.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(I)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731221 EC50 42.0 nM
CSc1ccc(NC(=O)Nc2c(C(C)C)n(C)n(-c3cncnc3)c2=O)cc1 CHEMBL211220 EC50 43.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2F)c(F)c1 CHEMBL4797598 EC50 43.0 nM
COc1cccc(Cc2c(C)c(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)c1 CHEMBL5271505 EC50 43.0 nM
CC(C)c1c(NC(=O)Nc2ccc(C(F)(F)F)cc2)c(=O)n(-c2cnc3ccccc3c2)n1C CHEMBL380389 EC50 44.0 nM
COCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727690 EC50 44.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4072201 IC50 44.0 nM
NCc1ccc(CNC(=O)[C@H]2[C@H](C(=O)Nc3ncc(Br)s3)[C@@H]3C=C[C@H]2C32CC2)cc1 CHEMBL3729184 EC50 45.0 nM
Cc1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cc1 CHEMBL3728190 EC50 46.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2cc(F)c(Br)c(F)c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730955 EC50 46.0 nM
O=C(CCCN1CCCC1=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731426 EC50 47.0 nM
O=C(NCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730671 EC50 49.0 nM
CN1CCN(CCCNC(=O)[C@H]2[C@H](C(=O)Nc3ncc(Br)s3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3730506 EC50 49.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)NC2(c3cccc(C(F)(F)F)c3)CC2)c(F)c1 CHEMBL5283221 EC50 49.0 nM
O=C(Nc1ccc(Cl)cc1)N[C@@H](Cc1ccccc1)C(=O)N1CCCCC1 CHEMBL3588927 EC50 50.0 nM
CC(C)(O)c1coc(Cn2ncc(NC(=O)c3ncoc3-c3ccc(F)cc3)n2)n1 CHEMBL3959136 EC50 51.0 nM
CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2ccccc2OC)c1=O CHEMBL4454594 pEC50 51.29 nM
COC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3731492 EC50 52.0 nM
NCCCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730697 EC50 52.0 nM
CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O CHEMBL4536334 pEC50 52.48 nM
Cc1cccc(-c2oc(C3CC3)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 CHEMBL3935685 EC50 52.9 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4079416 IC50 53.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(OC(F)(F)F)cc3)o2)c(F)c1 CHEMBL5197524 EC50 53.0 nM
O=C(NCC1CCNCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732223 EC50 54.0 nM
CCN(CC)CCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727646 EC50 54.0 nM
NCCCCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733163 EC50 55.0 nM
O=C(NC1CNC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730324 EC50 57.0 nM
CC1(C)CN(c2ccc(-c3ccccc3P(C)(C)=O)c(F)c2F)C(=O)[C@@H]1NC(=O)Nc1cnc(Cl)cn1 CHEMBL5283999 EC50 57.0 nM
CC(C)CCN1CCC(NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3732502 EC50 58.0 nM
NCc1cccc(CNC(=O)[C@H]2[C@H](C(=O)NCc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)c1 CHEMBL3732601 EC50 59.0 nM
COc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCC(N)=O)[C@H]3CC[C@@H]2C32CC2)cc1 CHEMBL3730815 EC50 59.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccc(OC)cn3)CCCCC2)cc1 CHEMBL3588871 EC50 60.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCC2CCCCC2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728471 EC50 60.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4103322 IC50 60.0 nM
CC(C)(C)OC(=O)N1CCC[C@H](N2CCC(NC(=O)Nc3ccc(Br)cc3)C2=O)C1 CHEMBL5087410 EC50 60.0 nM
O=C(Cc1ccccc1Cl)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731223 EC50 61.0 nM
O=C(NCCc1ccccn1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732870 EC50 61.0 nM
O=C(N[C@H]1CC[C@@H](CO)CC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730665 EC50 61.0 nM
CN(C)CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729600 EC50 61.0 nM
O=C(NC1CC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730609 EC50 63.0 nM
CC(C)(CNC(=O)OC(C)(C)C)CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732602 EC50 63.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCN(C)C)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3728633 EC50 65.0 nM
O=C(Nc1ccc(Br)cc1)N[C@@H](CC1CC1)C(=O)Nc1cccnc1 CHEMBL4779558 EC50 68.0 nM
O=C(NC1CCC(O)CC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728538 EC50 69.0 nM
O=C(Nc1ccnn1-c1ccccc1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729807 EC50 70.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)Nc1cccnn1)C1CCCC1 CHEMBL4748148 EC50 70.0 nM
Cc1nc(CC(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)c(C)s1 CHEMBL3732813 EC50 71.0 nM
CC1CCC(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)CC1 CHEMBL3728342 EC50 71.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728499 EC50 71.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(Oc4ccc(C(F)(F)F)nc4)cc3)o2)c(F)c1 CHEMBL5273792 EC50 71.0 nM
COCCC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732041 EC50 72.0 nM
CCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729543 EC50 72.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)Nc1cccnc1)C1CCOCC1 CHEMBL4791407 EC50 72.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2nc(Br)cs2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728393 EC50 73.0 nM
CCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732418 EC50 73.0 nM
NCCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727378 EC50 76.0 nM
Cc1nc(CCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@H]3C=C[C@@H]2C32CC2)[nH]c1C CHEMBL3730664 EC50 77.0 nM
CCn1nc(C)cc1CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728092 EC50 77.0 nM
CCCCCNC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3732930 EC50 79.0 nM
CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2cnc3ccccc3c2)n1C CHEMBL210303 EC50 80.0 nM
CC(C)[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@@H](Cc1ccc2ccccc2c1)N1C[C@@H](Cc2ccc(O)cc2)N(CC2CCCCC2)C(=O)C1=O CHEMBL3590218 IC50 80.0 nM
CN(C)C(=O)CCC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728947 EC50 80.0 nM
CCN(CC)CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732416 EC50 80.0 nM
O=C(NCC(c1ccccc1)N1CCOCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732008 EC50 80.0 nM
O=C(NCCCCO)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730490 EC50 80.0 nM
Cc1ccc(NC(=O)Nc2c(C(C)C)n(C)n(-c3ccccc3)c2=O)cc1F CHEMBL211957 EC50 81.0 nM
O=C(NC1CC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730215 EC50 82.0 nM
CC(C)CNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732014 EC50 82.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCN3CCNC3=O)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3730255 EC50 82.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(C(F)(F)F)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729485 EC50 82.0 nM
CC(C)(O)c1coc(Cn2ncc(NC(=O)c3ncsc3-c3cccc(F)c3)n2)n1 CHEMBL3977012 EC50 82.3 nM
Cc1ccc(NC(=O)Nc2c(C(C)(C)C)n(C)n(-c3ccccc3)c2=O)cc1F CHEMBL211595 EC50 83.0 nM
N#Cc1ccc(C[C@@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3ccc(F)cc32)cc1 CHEMBL5185982 IC50 85.0 nM
CC1(C(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1(Cl)Cl CHEMBL3731870 EC50 87.0 nM
COC(=O)CCCC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729231 EC50 88.0 nM
Cc1nn(C)cc1NC(=O)C1(NC(=O)Nc2ccc(Br)cc2)CCCC1 CHEMBL4779714 EC50 89.0 nM
Cc1c(NC(=O)Nc2ccc(Br)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL377969 EC50 90.0 nM
CCCCOc1ccc(C(=O)NN2Cc3ccccc3NC2c2ccc(OC)cc2)cc1 CHEMBL3590217 IC50 90.0 nM
CC(=O)c1ncc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)o1 CHEMBL3728344 EC50 92.0 nM
CC(C)Cc1cc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)no1 CHEMBL3730804 EC50 93.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccc(C(F)(F)F)cc3)Cc3ccc(C(F)(F)F)cc3)Cc3ccc(C(F)(F)F)cc3)Cc3ccc(C(F)(F)F)cc3)Cc3ccc(C(F)(F)F)cc3)Cc3ccc(C(F)(F)F)cc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4082656 IC50 94.0 nM
CC(=O)CCCCNC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3730358 EC50 95.0 nM
Cc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)nc1 CHEMBL3732432 EC50 95.0 nM
CC(C)(C)OC(=O)N1CCCC1CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728558 EC50 96.0 nM
O=C(NCCCO)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730036 EC50 96.0 nM
O=C(NCCN1CCOCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729813 EC50 97.0 nM
CCN(CC)CCCCNC(=O)[C@H]1[C@H](C(=O)NCc2nc(C(C)=O)cs2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730658 EC50 97.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)Nc1cccnc1)C1CC1 CHEMBL4756434 EC50 97.0 nM
CNCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729979 EC50 98.0 nM
CCn1c(C(C)C)c(NC(=O)Nc2ccc(C)c(F)c2)c(=O)n1-c1ccccc1 CHEMBL378064 EC50 100.0 nM
Cc1c(NC(=O)Nc2ccc(C(F)(F)F)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL211885 EC50 100.0 nM
COc1ccc(CCNC(=O)Nc2ccc(Br)cc2)cc1 CHEMBL1289381 EC50 100.0 nM
NC(=O)C1CCCCC1NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728007 EC50 100.0 nM
Cc1cccc(C2(NC(=O)N[C@@H]3C(=O)NC[C@H]3c3c(F)cc(Cl)cc3F)CC2)n1 CHEMBL5281612 EC50 100.0 nM
CC(=O)N1CCN(c2ccc(N3CCC[C@@H](NC(=O)Nc4ccc(C(F)(F)F)cc4)C3=O)cc2)CC1 CHEMBL5277650 EC50 100.0 nM
CCCCC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733047 EC50 103.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2cc(F)c(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733207 EC50 103.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCCc3nc4ccccc4[nH]3)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3733092 EC50 106.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccccc3)CC2)cc1 CHEMBL4168567 EC50 110.0 nM
O=C(Nc1ccc(Br)cc1)NC1(C(=O)Nc2ccc(Cl)nc2)CCCC1 CHEMBL4760670 EC50 110.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2c2nc3cc(Cl)ccc3[nH]2)c(F)c1 CHEMBL5169641 EC50 110.0 nM
O=C(NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)c1ccnn1-c1ccccc1 CHEMBL3730474 EC50 112.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732166 EC50 113.0 nM
NC(=O)CCC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731489 EC50 114.0 nM
Cc1cc(C(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)nn1C CHEMBL3731544 EC50 115.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(Br)c(F)c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728830 EC50 117.0 nM
Cc1ccncc1C(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732516 EC50 118.0 nM
CC(NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)C(=O)N1CCCCC1 CHEMBL3729615 EC50 118.0 nM
COc1c(F)cc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cc1F CHEMBL3728119 EC50 119.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ncc([N+](=O)[O-])s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727914 EC50 120.0 nM
O=C(Nc1ccc([N+](=O)[O-])cc1)N[C@H](Cc1cccnc1)C(=O)NCC1(c2ccccc2)CC1 CHEMBL4172556 EC50 120.0 nM
COc1cccc(-c2cc(C#N)c(C)n(CC(=O)Nc3ccc(Br)cc3)c2=O)c1 CHEMBL5278883 EC50 120.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ncc(Cl)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729966 EC50 121.0 nM
CCN(CC)CCCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732195 EC50 121.0 nM
O=C(NC1CCN(Cc2ccccc2)CC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730675 EC50 123.0 nM
CC(C)C(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729198 EC50 125.0 nM
O=C(NCC1(O)CCCCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3732017 EC50 129.0 nM
CCc1nc2ccccc2n1C1CCN(C(=O)c2cc3cc(OC)ccc3[nH]2)C1 CHEMBL248928 EC50 130.0 nM
CCOC(=O)C1CCN(C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)Nc2ccc(Br)cc2)CC1 CHEMBL3588923 EC50 130.0 nM
CCN1CCC(C(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3728768 EC50 131.0 nM
Cc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cn1 CHEMBL3727715 EC50 131.0 nM
CCCCCCN(C)C(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729626 EC50 133.0 nM
O=C(CCc1cccnc1)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732149 EC50 136.0 nM
CCc1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL209995 EC50 140.0 nM
CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@@H](Cc1ccc2ccccc2c1)N1C[C@@H](Cc2ccc(O)cc2)N(CC2CCCCC2)C(=O)C1=O CHEMBL3588922 EC50 140.0 nM
O=C(Nc1ccc(Br)cc1)N[C@@H](Cc1ccccc1)C(=O)N1CCCC1 CHEMBL3588925 EC50 140.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3731264 EC50 140.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3729817 EC50 140.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3cccnc32)cc1 CHEMBL5185462 IC50 140.0 nM
Cc1nn(C)cc1N1CCC(NC(=O)Nc2ccc(Br)cc2)C1=O CHEMBL5078594 EC50 142.0 nM
CC(C)(C)CCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729866 EC50 146.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732159 EC50 146.0 nM
CN1CCC(NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3729343 EC50 147.0 nM
CC(C)c1c(NC(=O)Nc2ccc(C(F)(F)F)cc2)c(=O)n(-c2cncnc2)n1C CHEMBL211555 EC50 150.0 nM
COc1cccc(Cc2c(-c3ccccc3)c(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)c1 CHEMBL5279627 EC50 150.0 nM
CC(=O)c1nc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)co1 CHEMBL3731379 EC50 153.0 nM
COCCC(=O)N(C)C[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727591 EC50 155.0 nM
O=C(NCCCN1CCOCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730081 EC50 156.0 nM
O=C(NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)c1cccc(F)c1Cl CHEMBL3728360 EC50 158.0 nM
O=C(NCCO)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3730683 EC50 158.0 nM
CCOC(=O)C1CCN(C(=O)[C@H](Cc2ccccc2)NC(=O)Nc2ccc(Br)cc2)CC1 CHEMBL3590207 EC50 160.0 nM
O=C(CCCN1CCCC1)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728805 EC50 160.0 nM
COc1ccc([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(Cl)cc3)o2)cc1 CHEMBL5204580 EC50 160.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3cc(F)ccc32)cc1 CHEMBL5199629 EC50 160.0 nM
N#Cc1cnc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)s1 CHEMBL3733176 EC50 166.0 nM
Cc1[nH]ncc1CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731458 EC50 168.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2cnc(Br)c(F)c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730082 EC50 168.0 nM
CSc1ccc(NC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1 CHEMBL214216 EC50 170.0 nM
CCCCOc1ccc(C(=O)NN2Cc3ccccc3NC2c2ccc(C)cc2)cc1 CHEMBL3590216 IC50 170.0 nM
CC(=O)c1coc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3731893 EC50 170.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)NC2CCCCNC2=O)cc1 CHEMBL5196771 EC50 170.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccco2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728843 EC50 173.0 nM
O=C(NCCCc1nc2ccccc2[nH]1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731251 EC50 174.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2ccc(C#N)cc2)C(=O)NCC2(c3cccc(O)c3)CC2)cc1 CHEMBL5265989 EC50 180.0 nM
O=C(NCCN1CCNC1=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733127 EC50 181.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)NCC2(c3ccc(F)c(Cl)c3)CC2)cc1 CHEMBL4162930 EC50 190.0 nM
CC(C)CNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728826 EC50 191.0 nM
CC(C)(C)OC(=O)CCCNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728883 EC50 191.0 nM
CC(C)(C)OC(=O)CNc1cccc(CNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)c1 CHEMBL3728708 EC50 194.0 nM
O=C(NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)C1CCCC1 CHEMBL3728585 EC50 200.0 nM
CCCN(CC1CC1)C(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728613 EC50 200.0 nM
CC(C)(C)OC(=O)N1CCC(CNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3728389 EC50 204.0 nM
O=C(N[C@H]1CC[C@H](CN2CCCC2)CC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732371 EC50 208.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2cnc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727792 EC50 213.0 nM
CN1CCN(CCCNC(=O)[C@H]2[C@H](C(=O)NCc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3730632 EC50 213.0 nM
O=C(NCCCc1nc2ccccc2[nH]1)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728352 EC50 216.0 nM
O=C(NC1CCCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730033 EC50 216.0 nM
CC(C)(C)OC(=O)N1CCC(NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)CC1 CHEMBL3730306 EC50 218.0 nM
CC(=O)c1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)s1 CHEMBL3729225 EC50 223.0 nM
NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728553 EC50 223.0 nM
CC(C)C[C@H](NC(=O)CNC(=O)Nc1ccc(Br)cc1)C(=O)O CHEMBL5276622 EC50 224.0 nM
COc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccc(OC)cn3)CCCCC2)cc1 CHEMBL3589946 EC50 230.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(C2CCNCC2)C1=O CHEMBL5075000 EC50 230.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)c(F)c2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730781 EC50 236.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730424 EC50 240.0 nM
N#Cc1ccc(C[C@@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3ccc(F)cc3C2)cc1 CHEMBL5184913 IC50 240.0 nM
CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2cncnc2)n1C CHEMBL379853 EC50 250.0 nM
O=C(Nc1ccc(Br)cc1)N[C@@H](Cc1ccccc1)C(=O)N1CCc2ccccc21 CHEMBL3590208 EC50 250.0 nM
O=C(Nc1ccc(Br)cc1)NC1(C(=O)Nc2cccnc2)CCCC1 CHEMBL4797594 EC50 250.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(CC2CCN(Cc3ccccc3)CC2)C1=O CHEMBL5085435 EC50 250.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccccc3)o2)c(F)c1 CHEMBL5187399 EC50 250.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2ncc(-c3ccc(Cl)cc3)o2)c(F)c1 CHEMBL5201015 EC50 250.0 nM
Cc1nc(CC(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)cs1 CHEMBL3731676 EC50 252.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cn2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733330 EC50 258.0 nM
COc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccccc3)CCCCC2)cc1 CHEMBL3590070 EC50 260.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3ccc(F)cc3C2)cc1 CHEMBL5187563 IC50 260.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(OC(F)(F)F)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729208 EC50 263.0 nM
CN(C)CC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729083 EC50 265.0 nM
CCc1ccc2[nH]c(C(=O)N3CC[C@@H](n4c(CC)nc5ccccc54)C3)cc2c1 CHEMBL249742 EC50 270.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3cccnc3)CCCCC2)cc1 CHEMBL3590071 EC50 270.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(CC2CCNCC2)C1=O CHEMBL5084374 EC50 270.0 nM
O=C(Nc1ccc(Br)cc1)NC1(C(=O)NCc2nn[nH]n2)CCCC1 CHEMBL4786842 EC50 272.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCCN)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3729427 EC50 273.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4094101 IC50 273.0 nM
Cc1cc(Br)ccc1NC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3730378 EC50 275.0 nM
Cc1nn(-c2ccccc2)c(C)c1N1CCC(NC(=O)Nc2ccc(Br)cc2)C1=O CHEMBL5076199 EC50 280.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCCN(C)C)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3733076 EC50 288.0 nM
COc1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)c(F)c1F CHEMBL3733253 EC50 290.0 nM
CN(C)CCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727453 EC50 290.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCC(N)=O)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3729761 EC50 297.0 nM
CN(C[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)C(=O)Cc1ccccc1Cl CHEMBL3732583 EC50 298.0 nM
CSc1ccc(NC(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCCCC2)cc1 CHEMBL3588928 EC50 300.0 nM
CNOC(=O)C1CCN(C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)Nc2ccc(Br)cc2)CC1C CHEMBL3588924 EC50 300.0 nM
N#Cc1ccc(C[C@@H](NC(=O)Nc2ccc(F)cc2)C(=O)NCC2(c3ccc(F)c(Cl)c3)CC2)cc1 CHEMBL4173645 EC50 300.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(c2ccccc2)C1=O CHEMBL5076914 EC50 300.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2cc(F)c(Br)cc2F)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731680 EC50 301.0 nM
Cc1cc(C(=O)N(C)C[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)nn1C CHEMBL3732650 EC50 303.0 nM
O=C(NCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3727729 EC50 305.0 nM
CCC[C@H](NC(=O)CNC(=O)Nc1ccc(Br)cc1)C(=O)O CHEMBL5276878 EC50 308.0 nM
CCc1c(NC(=O)Nc2ccc(C)c(F)c2)c(=O)n(-c2ccccc2)n1C CHEMBL212113 EC50 310.0 nM
COc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccccn3)CCCCC2)cc1 CHEMBL3590074 EC50 310.0 nM
O=C(CC1CC1)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728604 EC50 315.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCCOc2ccccc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728166 EC50 319.0 nM
Cc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCC(N)=O)[C@H]3C=C[C@@H]2C32CC2)nc1 CHEMBL3729765 EC50 330.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2ccc(C#N)cc2)C(=O)NCC2(c3ccc(F)c(Cl)c3)CC2)cc1 CHEMBL4159569 EC50 330.0 nM
CC(C)(CO)NC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3727702 EC50 333.0 nM
Cn1c(CCC(=O)NC[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)nc2ccccc21 CHEMBL3727668 EC50 336.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2Cc3ccccc3C2)cc1 CHEMBL5185921 EC50 340.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2cnc(Br)c(F)c2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3729273 EC50 349.0 nM
CNCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729916 EC50 350.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(C2CCN(Cc3ccccc3)CC2)C1=O CHEMBL5070452 EC50 350.0 nM
CC(C)CCNC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3731214 EC50 352.0 nM
O=C(NCCF)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728109 EC50 354.0 nM
O=C(CNC(=O)Nc1ccc(Br)cc1)N[C@@H](Cc1ccccc1)C(=O)O CHEMBL5280317 EC50 356.0 nM
CCCCNC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3728370 EC50 365.0 nM
O=C(Nc1ccc(Br)cc1)NC1(C(=O)Nc2cncnc2)CCCC1 CHEMBL4751781 EC50 366.0 nM
NCc1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)cc1 CHEMBL3728437 EC50 367.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc(Br)c(Cl)c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732539 EC50 367.0 nM
CC(=O)c1coc(CNC(=O)[C@H]2[C@H](C(=O)NCC(C)C)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3731384 EC50 369.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(C2CCN(Cc3ccccc3)C2)C1=O CHEMBL5085818 EC50 370.0 nM
CNC(=O)[C@H](NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1)C(C)(C)C CHEMBL3729032 EC50 373.0 nM
O=C(Nc1ccc(C(F)(F)F)cn1)N[C@@H]1CCCN(c2ccc(N3CC4(COC4)C3)cc2)C1=O CHEMBL5270501 EC50 380.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCC3CCNCC3)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3731785 EC50 384.0 nM
COc1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cc1F CHEMBL3729027 EC50 389.0 nM
CC(C)(C)OC(=O)NCc1ccc(CNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)cc1 CHEMBL3728252 EC50 391.0 nM
COc1ccc(CCNC(=O)Nc2ccc(Cl)cc2)cc1 CHEMBL1289260 EC50 400.0 nM
CC(C)(C)OC(=O)N1CCC(CN2CCC(NC(=O)Nc3ccc(Br)cc3)C2=O)CC1 CHEMBL5090603 EC50 400.0 nM
CC(C)(C)OC(=O)N1CC(N2CCC(NC(=O)Nc3ccc(Br)cc3)C2=O)C1 CHEMBL5080179 EC50 410.0 nM
N#Cc1ccc(C[C@@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCc3cc(F)ccc32)cc1 CHEMBL5184490 EC50 410.0 nM
COc1ccc(NC(=O)N[C@H](Cc2ccc(O)cc2)C(=O)NCC2(c3ccccc3)CC2)cc1 CHEMBL5282050 EC50 410.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccccn3)CCCCC2)cc1 CHEMBL3590073 EC50 430.0 nM
NC(=O)c1ccccc1-c1ccc(N2CCC[C@@H](NC(=O)Nc3ccc(F)cc3)C2=O)cc1 CHEMBL5288471 EC50 450.0 nM
Cc1cnc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)s1 CHEMBL3727588 EC50 463.0 nM
O=C(CCc1cc2ccccc2[nH]1)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731359 EC50 463.0 nM
CC(C)(C)OC(=O)NCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728194 EC50 467.0 nM
CC(C)(C)OC(=O)N1CC(NC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)C1 CHEMBL3731092 EC50 477.0 nM
CC(=O)c1csc(CNC(=O)[C@H]2[C@H](C(=O)NCCCN3CCN(C)CC3)[C@H]3C=C[C@@H]2C32CC2)n1 CHEMBL3728337 EC50 477.0 nM
Cc1nn(C)cc1NC(=O)C(NC(=O)Nc1ccc(Br)cc1)C1CCCC1 CHEMBL4754119 EC50 480.0 nM
Cc1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C CHEMBL210298 EC50 490.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)Nc2ccc3ncoc3c2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728646 EC50 492.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)NC1CNC1)C1CCCC1 CHEMBL4793549 EC50 500.0 nM
CCCC(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728603 EC50 505.0 nM
O=C(Nc1ccc(Br)cc1)NC1CCN(c2ccc(F)cc2)C1=O CHEMBL5085666 EC50 510.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCc2ccc(F)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732392 EC50 514.0 nM
COc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCC(=O)O)[C@H]3C=C[C@@H]2C32CC2)cc1 CHEMBL3731200 EC50 516.0 nM
CC(C)(C)OC(=O)NCCCCCNC(=O)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3728159 EC50 519.0 nM
O=C(CCc1ccc(F)cc1)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730596 EC50 529.0 nM
CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(C2=NCCS2)n1C CHEMBL377130 EC50 540.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)NCC1CCCO1)C1CCCC1 CHEMBL4759517 EC50 540.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N[C@H]1CCCN(c2ccc(N3CC4(COC4)C3)cc2)C1=O CHEMBL5273815 EC50 540.0 nM
CC(C)(C)OC(=O)N1CCCC(CCNC(=O)[C@H]2[C@H](C(=O)Nc3ccc(Br)cc3)[C@@H]3C=C[C@H]2C32CC2)C1 CHEMBL3727655 EC50 552.0 nM
Cc1ccc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)o1 CHEMBL3733305 EC50 556.0 nM
Cc1nc2ccc(NC(=O)[C@H]3[C@H](C(=O)NCCCCN4CCCC4)[C@H]4C=C[C@@H]3C43CC3)cc2s1 CHEMBL3732799 EC50 570.0 nM
COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccccc3)c2=O)c1 CHEMBL561375 EC50 600.0 nM
COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccc(Br)cc3)c2=O)c1 CHEMBL564392 EC50 600.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)NC1CCOCC1)C1CCCC1 CHEMBL4757408 EC50 600.0 nM
Cc1ccc(NC(=O)C2(NC(=O)Nc3ccc(Br)cc3)CCCC2)cn1 CHEMBL4794472 EC50 600.0 nM
CC1(C)CN(C(=O)[C@H](Cc2ccc(C#N)cc2)NC(=O)Nc2ccc(F)cc2)Cc2cc(F)ccc21 CHEMBL5193947 IC50 600.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)NC1COC1)C1CCCC1 CHEMBL4757032 EC50 620.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc([N+](=O)[O-])cc2)C(=O)NCC2(c3ccccc3)CC2)cc1 CHEMBL4172968 EC50 630.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccnc(F)c3)CCCCC2)cc1 CHEMBL3589947 EC50 660.0 nM
COc1ccc(NC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)cn1 CHEMBL3728237 EC50 673.0 nM
O=C(NCCF)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732201 EC50 673.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2c2nc3ccccc3[nH]2)c(F)c1 CHEMBL5208504 EC50 680.0 nM
CCc1nc2ccccc2n1C1CCN(C(=O)c2cc3cc(OC)ccc3[nH]2)CC1 CHEMBL250347 EC50 690.0 nM
O=C(/C=C/c1ccccc1)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732009 EC50 697.0 nM
O=C(Nc1ccc([N+](=O)[O-])cc1)N[C@@H](Cc1cccnc1)C(=O)NCC1(c2ccccc2)CC1 CHEMBL4164673 EC50 730.0 nM
COc1ccc(NC(=O)N[C@H](Cc2ccc(C#N)cc2)C(=O)NCC2(c3ccc(F)c(Cl)c3)CC2)cc1 CHEMBL4170201 EC50 730.0 nM
O=C(CNC(=O)Nc1ccc(Br)cc1)Nc1cccnc1 CHEMBL4762222 EC50 730.0 nM
CC(C)(C)OC(=O)N1CCC(N2CCC(NC(=O)Nc3ccc(Br)cc3)C2=O)CC1 CHEMBL5087710 EC50 730.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCCc2ccccc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3732365 EC50 731.0 nM
COC[C@H](Cc1ccccc1)NC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3731705 EC50 735.0 nM
CC(=O)CCCNC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1 CHEMBL3727528 EC50 748.0 nM
CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1 CHEMBL4067361 IC50 759.0 nM
CCc1ccc(NC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1 CHEMBL378679 EC50 770.0 nM
COc1ccc(NC(=O)N[C@@H]2CCCN(c3ccc(-c4ccccc4C(N)=O)cc3)C2=O)cc1Cl CHEMBL5276320 EC50 780.0 nM
O=C(Nc1ccc(Br)cc1)NC(C(=O)Nc1cncnc1)C1CCCC1 CHEMBL4761978 EC50 800.0 nM
CCc1nc2ccccc2n1[C@@H]1CCN(C(=O)c2cc3cc(Br)ccc3[nH]2)C1 CHEMBL249537 EC50 810.0 nM
Cc1onc(-c2ccccc2)c1CNC(=O)[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3733039 EC50 812.0 nM
COc1ccc2[nH]c(C(=O)N3CCC(n4c(CC(C)C)nc5ccccc54)CC3)cc2c1 CHEMBL400089 EC50 830.0 nM
O=C(NCCCCN1CCCC1)[C@H]1[C@H](C(=O)NCCCn2ccnc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730904 EC50 835.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2nnc(-c3ccc(Cl)cc3F)o2)c(F)c1 CHEMBL5203364 EC50 840.0 nM
O=C(N[C@H]1CC[C@H](CO)CC1)[C@H]1[C@H](C(=O)Nc2ncc(Br)s2)[C@@H]2CC[C@H]1C21CC1 CHEMBL3731851 EC50 855.0 nM
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccc(F)cc3)CCCCC2)cc1 CHEMBL3590075 EC50 860.0 nM
NC(=O)CCNC(=O)[C@H]1[C@H](C(=O)NCc2cnc(Br)s2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3728104 EC50 884.0 nM
CC(C)n1cc(N2CCC(NC(=O)Nc3ccc(Br)cc3)C2=O)cn1 CHEMBL5084099 EC50 884.0 nM
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2Nc2cc(-c3ccc(C(F)F)cc3)on2)c(F)c1 CHEMBL5291461 EC50 890.0 nM
CC(NC(=O)[C@H]1[C@H](C(=O)NCCCCN2CCCC2)[C@H]2C=C[C@@H]1C21CC1)c1ccc(Br)cc1 CHEMBL3732885 EC50 898.0 nM
CCOCCCNC(=O)[C@H]1[C@H](C(=O)NCc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3729806 EC50 899.0 nM
COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(C)cc3)c2=O)c1 CHEMBL539401 EC50 900.0 nM
COc1ccc(CCNC(=O)Nc2ccc(F)cc2)cc1 CHEMBL1289379 EC50 900.0 nM
CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)C(C)C CHEMBL4084411 IC50 900.0 nM
COc1cc(F)c(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)c(F)c1 CHEMBL3728165 EC50 912.0 nM
Cc1nn(C)c(Cl)c1C(=O)NC[C@H]1[C@H](C(=O)Nc2ccc(Br)cc2)[C@@H]2C=C[C@H]1C21CC1 CHEMBL3730978 EC50 963.0 nM
Cc1ccc(NC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1F CHEMBL212109 EC50 980.0 nM
N#Cc1ccc(C[C@H](NC(=O)Nc2ccc(F)cc2)C(=O)N2CCCCC2)cc1 CHEMBL5187530 EC50 980.0 nM
CC(=O)c1ncc(CNC(=O)[C@H]2[C@H](C(=O)NCCCCN3CCCC3)[C@H]3C=C[C@@H]2C32CC2)s1 CHEMBL3727461 EC50 994.0 nM
COc1cccc(C(=O)c2cc(C)nn(CC(=O)Nc3ccc(Br)cc3)c2=O)c1 CHEMBL2391446 EC50 1000.0 nM
N#Cc1ccc(C[C@@H](NC(=O)Nc2ccc(F)cc2)C(=O)NC2CCCCNC2=O)cc1 CHEMBL5176452 EC50 1000.0 nM