Cc1csc(-c2cc(-c3ccncc3)c3n(c2=O)CCCc2ccncc2-3)n1 CHEMBL45198 Ki 0.5 nM
Cc1cc(-c2nnc3c4ccccc4c(OCc4cn(C)nn4)nn23)no1 CHEMBL306422 Ki 0.61 nM
Cn1ncnc1COc1nn2c(-c3cc(F)ccc3F)nnc2cc1C(C)(C)C CHEMBL373250 Ki 0.7 nM
Cc1cc(-c2nncc3c(C(C)(C)C)c(OCc4ncnn4C)nn23)no1 CHEMBL363211 Ki 0.77 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2 CHEMBL407 pKi 1.0 nM
c1ccc2c(c1)[nH]c1c2ncc2[nH]c3ccccc3c21 CHEMBL301605 Ki 1.0 nM
CCCNC(=O)c1nnc2c(-c3c(F)cccc3OC)cccc2c1N CHEMBL1783282 Ki 1.3 nM
CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4c(F)cccc4C#N)c3)cnc2n1 CHEMBL204696 Ki 1.8 nM
CCOC(=O)c1ncc2[nH]c3ccc(OC)cc3c2c1COC CHEMBL5280240 Ki 2.0 nM
CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1 CHEMBL49141 Ki 2.0 nM
CCCNC(=O)c1nnc2c(-c3cc(OC)ccc3OC)cccc2c1N CHEMBL1783256 Ki 3.1 nM
COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12 CHEMBL454095 Ki 4.0 nM
CCc1c(C(=O)OC)nc(C)c2[nH]c3cc(OC)c(OC)cc3c12 CHEMBL5290579 Ki 4.0 nM
CCOC(=O)c1nc(C)c2[nH]c3cc(OC)c(OC)cc3c2c1CC CHEMBL5275690 Ki 4.0 nM
CCOC(=O)c1ncc2[nH]c3ccccc3c2c1COC CHEMBL5266498 Ki 5.0 nM
CCOC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL454606 Ki 6.0 nM
CCOC(=O)c1ncc2[nH]c3ccc(OCc4ccccc4)cc3c2c1COC CHEMBL1518572 Ki 6.0 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(N=[N+]=[N-])ccc1-2 CHEMBL6597 Ki 7.0 nM
CCOC(=O)c1ncc2[nH]c3ccc(O)cc3c2c1COC CHEMBL5290464 Ki 11.0 nM
COc1ccc2c(c1)[nH]c1c2ncc2[nH]c3ccccc3c21 CHEMBL497197 Ki 11.0 nM
c1ccc(-c2nnc3c4c(c(OCc5ccccn5)nn23)C2CCC4CC2)cc1 CHEMBL178942 Ki 12.0 nM
Clc1ccc2c(c1)-c1ncnn1Cc1c(Cl)ncn1-2 CHEMBL1077391 Ki 14.0 nM
c1ccc2c(c1)[nH]c1cnc3c4cccnc4[nH]c3c12 CHEMBL2008708 Ki 16.0 nM
CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc21 CHEMBL12 Ki 17.0 nM
CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1cc(OC)ccc1-2 CHEMBL52030 Ki 17.0 nM
C#Cc1ccc2c(c1)C(=O)N(C)Cc1c(C(=O)OC(C)(C)C)ncn1-2 CHEMBL58757 Ki 18.7 nM
CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL509197 Ki 19.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1ccccc1)CC2 CHEMBL356161 EC50 20.0 nM
CCCC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL510764 Ki 21.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1cccnc1)CC2 CHEMBL146086 EC50 23.0 nM
Cc1c(F)c(Nc2ccc(-c3cn(C)cn3)cn2)cc2c1ncn2CC1CC1 CHEMBL4581355 Ki 24.0 nM
Clc1ccc2c(c1)[nH]c1c2ncc2[nH]c3ccccc3c21 CHEMBL496990 Ki 24.0 nM
C#Cc1ccc2c(c1)C(=O)N(C)Cc1c(C(=O)OCC)ncn1-2 CHEMBL286594 Ki 25.8 nM
c1ccc2c(c1)[nH]c1cnc3c4ccncc4[nH]c3c12 CHEMBL5281056 Ki 31.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1ccncc1)CC2 CHEMBL342270 EC50 33.0 nM
COC(=O)c1cc2c(cn1)[nH]c1ccc(NCc3ccccc3)cc12 CHEMBL5290746 Ki 49.0 nM
O=C(c1cccc(F)c1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL356806 EC50 65.0 nM
Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2 CHEMBL661 EC50 69.0 nM
CCCOc1cc2c(cn1)[nH]c1ccccc12 CHEMBL499814 Ki 69.0 nM
CC(=O)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL149549 EC50 71.0 nM
COC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL453066 Ki 72.0 nM
FC(F)c1ncn2c1Cn1ncnc1-c1cc(Br)ccc1-2 CHEMBL1080588 Ki 80.0 nM
C#Cc1ccc2c(c1)C(c1ccccc1)=NCc1c(C(=O)OCC)ncn1-2 CHEMBL522055 Ki 96.0 nM
C#Cc1ccc2[nH]c3cnc(C(=O)OC(C)(C)C)cc3c2c1 CHEMBL1270038 Ki 100.0 nM
CCC(=O)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL358519 EC50 116.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(c1ncccn1)CC2 CHEMBL146488 EC50 117.0 nM
Cc1ccccc1C(=O)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL344120 EC50 119.0 nM
O=C(c1ccc(F)c(F)c1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL147590 EC50 148.0 nM
C#Cc1ccc2c(c1)c(=O)n(C)c1c(C(=O)OCC)ncn21 CHEMBL471978 Ki 198.0 nM
C#Cc1ccc2c(c1)C(c1ccccn1)=NCc1c(-c3cnco3)ncn1-2 CHEMBL4062225 Ki 205.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(CC1CCCCC1)CC2 CHEMBL146230 EC50 213.0 nM
O=C(c1ccccc1F)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL146302 EC50 242.0 nM
CN1CC2C(C(=O)OC(C)(C)C)=NCN2c2ccc(C#C[Si](C)(C)C)cc2C1=O CHEMBL471977 Ki 255.0 nM
Cc1ccc(C(=O)N2CCc3nc(O)n4cc(-c5ccccc5F)nc4c3C2)cc1 CHEMBL343471 EC50 265.0 nM
C#Cc1ccc2c(c1)C(c1ccccc1)=NCc1c(C(=O)OCCCOC(=O)c3ncn4c3CN=C(c3ccccc3)c3cc(C#C)ccc3-4)ncn1-2 CHEMBL505768 Ki 272.0 nM
COCc1ncn2c1CN(C)C(=O)c1cc(Cl)ccc1-2 CHEMBL45346 Ki 328.0 nM
C=CCN1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL358301 EC50 344.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1cccs1)CC2 CHEMBL147364 EC50 367.0 nM
COc1ccc(C(=O)N2CCc3nc(O)n4cc(-c5ccccc5F)nc4c3C2)cc1 CHEMBL146317 EC50 375.0 nM
CCCCN1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL147379 EC50 394.0 nM
Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1 CHEMBL911 Ki 400.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(CC1CC1)CC2 CHEMBL145970 EC50 424.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1c[nH]cn1)CC2 CHEMBL358874 EC50 425.0 nM
C#Cc1ccc2c(c1)C(c1ccccc1F)=N[C@H](C)c1c(C(=O)NC3CC3)ncn1-2 CHEMBL4553352 Ki 480.0 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3681419 Ki 489.0 nM
Oc1nc2c(c3nc(-c4ccc(F)cc4F)cn13)CN(Cc1ccccc1)CC2 CHEMBL343009 EC50 500.0 nM
C#Cc1ccc2c(c1)C(c1ccccc1F)=N[C@H](C)c1c(C(=O)NC)ncn1-2 CHEMBL4228824 Ki 660.0 nM
C#Cc1ccc2c(c1)C(=O)N(C)Cc1c(C(=O)OCCCOC(=O)c3ncn4c3CN(C)C(=O)c3cc(C#C)ccc3-4)ncn1-2 CHEMBL35571 Ki 858.0 nM
CCN1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL147217 EC50 935.0 nM
C#Cc1ccc2c(c1)C(c1ccccn1)=NCc1c(C(=O)OC)ncn1-2 CHEMBL4537371 Ki 1000.0 nM
CC(OC(=O)c1cc2c(cn1)[nH]c1ccccc12)c1ccccc1 CHEMBL1270841 Ki 1000.0 nM