Cc1onc(-c2ccc(Cl)cn2)c1COC(O)Cc1ccc(C(N)=O)cn1 CHEMBL3681588 Ki 0.1 nM
Cc1onc(-c2ccc(Cl)cn2)c1COC(c1ccc(C(N)=O)cn1)C(F)(F)F CHEMBL3681586 Ki 0.2 nM
Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3676421 Ki 0.3 nM
Cc1onc(-c2ccc(Cl)cn2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676424 Ki 0.3 nM
Cc1onc(-c2ccc(Cl)cn2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3676425 Ki 0.3 nM
Cc1onc(-c2ccc(Cl)cn2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3676426 Ki 0.3 nM
Cc1onc(C2CCC(F)CN2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3676436 Ki 0.3 nM
Cc1onc(-c2ccc(Cl)cn2)c1COC(c1ccc(C(N)=O)cn1)C1CC1 CHEMBL3681585 Ki 0.3 nM
CCOC(=O)c1ncn2c1c(=O)n(Cc1cccnc1)c1ccccc12 CHEMBL5268764 Ki 0.3 nM
Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)NCCO)cn1 CHEMBL3676422 Ki 0.4 nM
Cc1onc(C2CCC(F)CN2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676435 Ki 0.4 nM
Cc1onc(C2CCC(F)CN2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3639753 Ki 0.4 nM
Cc1onc(-c2ccc(Cl)cn2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3681587 Ki 0.4 nM
Cc1onc(-c2ccc(Cl)cc2F)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681567 Ki 0.4 nM
CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1cc(OC)ccc1-2 CHEMBL52030 Ki 0.45 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2 CHEMBL407 Kd 0.5 nM
CCNC(=O)c1ccc(OCc2c(-c3ccc(F)cn3)noc2C)nc1 CHEMBL3676423 Ki 0.5 nM
Cc1onc(C2CCCCN2)c1COc1ccc(C(=O)NCCO)cn1 CHEMBL3676433 Ki 0.5 nM
Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)N[C@@H](C)C(F)(F)F)cn1 CHEMBL3681583 Ki 0.5 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N[C@@H](C)CO)cn1 CHEMBL3681554 Ki 0.5 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N[C@H]2CCC[C@@H]2O)cn1 CHEMBL3681557 Ki 0.5 nM
Cc1cc(-c2nnc3c4ccccc4c(OCc4ccccn4)nn23)no1 CHEMBL68684 Ki 0.5 nM
Cc1onc(C2CCC(F)CN2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3676437 Ki 0.6 nM
Cc1onc(C2CNCC(Cl)C2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676448 Ki 0.6 nM
Cc1onc(-c2ccc(F)cn2)c1COCc1ccc(C(N)=O)cn1 CHEMBL3681584 Ki 0.6 nM
Cc1onc(-c2ccc(Cl)cn2)c1COC(O)C(C)(C)c1ccc(C(N)=O)cn1 CHEMBL3681582 Ki 0.6 nM
Cc1onc(-c2ccc(Cl)cn2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3639804 Ki 0.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)C(F)(F)F)cn1 CHEMBL3681531 Ki 0.6 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681570 Ki 0.6 nM
Cn1c(=O)c2cc(Cl)ccc2n2cnc(C(=O)OC(C)(C)C)c12 CHEMBL458147 Ki 0.65 nM
Cc1cc(-c2nnc3c4ccccc4c(OCc4cn(C)nn4)nn23)no1 CHEMBL306422 Ki 0.66 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3676556 Ki 0.7 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N[C@@H]2CCC[C@H]2O)cn1 CHEMBL3681556 Ki 0.7 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681425 Ki 0.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H](C)CO)cn1 CHEMBL3681498 Ki 0.7 nM
CC[C@@H](CO)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681508 Ki 0.7 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681416 Ki 0.8 nM
Cc1ccc(-c2noc(C)c2COc2ccc(C(=O)NC(C)C)cn2)c(F)c1 CHEMBL3681550 Ki 0.8 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)Nc2cnn(C)c2)cn1 CHEMBL3681552 Ki 0.8 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N[C@H](C)CO)cn1 CHEMBL3681553 Ki 0.8 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681427 Ki 0.8 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(Cl)ccc1-2 CHEMBL415290 Ki 0.85 nM
Cc1ccc(-c2noc(C)c2COc2ccc(C(=O)NC3CCOCC3)cn2)cc1 CHEMBL3681548 Ki 0.9 nM
CCOC(=O)c1[nH]cc2nc3cc(OC)c(OC)cc3c-2c1CC CHEMBL85861 Kd 1.0 nM
Cc1ccc(-c2noc(C)c2COc2ccc(C(=O)NC(C)C)cn2)cc1 CHEMBL3681549 Ki 1.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)CO)cn1 CHEMBL3681492 Ki 1.0 nM
CCc1c(C(=O)OC)nc(C)c2[nH]c3cc(OC)c(OC)cc3c12 CHEMBL5290579 Ki 1.0 nM
CCNC(=O)c1ccc(OCc2c(C3CCCCN3)noc2C)nc1 CHEMBL3676431 Ki 1.1 nM
COCCNC(=O)c1ccc(OCc2c(C3CCCCN3)noc2C)nc1 CHEMBL3676434 Ki 1.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2cnn(C)c2)cn1 CHEMBL3681534 Ki 1.1 nM
Cc1nnc(-c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)[nH]1 CHEMBL3681543 Ki 1.1 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681415 Ki 1.1 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681569 Ki 1.1 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681426 Ki 1.1 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681572 Ki 1.1 nM
CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4c(F)cccc4C#N)c3)cnc2n1 CHEMBL204696 Ki 1.1 nM
Cc1onc(C2CCC(F)CN2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 CHEMBL3676438 Ki 1.2 nM
Cc1onc(C2CNCC(F)C2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676447 Ki 1.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CC(OCc3ccccc3)C2)cn1 CHEMBL3681524 Ki 1.2 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3676554 Ki 1.2 nM
CNC(=O)c1ccc(OCc2c(C3CCCCN3)noc2C)nc1 CHEMBL3676430 Ki 1.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3676478 Ki 1.3 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N[C@@H](C)C(F)(F)F)cn1 CHEMBL3681555 Ki 1.3 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3681424 Ki 1.3 nM
Cc1cc(-c2nncc3c(C(C)(C)C)c(OCc4ncnn4C)nn23)no1 CHEMBL363211 Ki 1.4 nM
Cc1cc(C(=O)NC2CCOCC2)cnc1OCc1c(-c2ccccc2)noc1C CHEMBL3676516 Ki 1.4 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2(C)COC2)cn1 CHEMBL3681529 Ki 1.4 nM
CCOC(=O)C1=NCN2c3ccc(CC)cc3C(=O)N(C)CC12 CHEMBL454865 Kd 1.5 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3676555 Ki 1.5 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3681573 Ki 1.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H]2CCC[C@H]2O)cn1 CHEMBL3681513 Ki 1.6 nM
COC(=O)c1ccc(OCc2c(-c3ccc(Cl)cn3)noc2C)nc1 CHEMBL3681580 Ki 1.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H]2CCOC2)cn1 CHEMBL3681502 Ki 1.6 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681574 Ki 1.6 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676542 Ki 1.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H](C)CO)cn1 CHEMBL3681497 Ki 1.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(CO)CO)cn1 CHEMBL3681501 Ki 1.7 nM
Cc1ncc(Cn2c(=O)c3cncn3c3ccccc32)cn1 CHEMBL5283158 Ki 1.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H](CO)C(C)C)cn1 CHEMBL3681506 Ki 1.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H](C)C(F)(F)F)cn1 CHEMBL3681532 Ki 1.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(F)F)cn1 CHEMBL3676463 Ki 2.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(O)CO)cn1 CHEMBL3681518 Ki 2.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H]2CCC[C@@H]2O)cn1 CHEMBL3681512 Ki 2.0 nM
COC(=O)c1ccc(OCc2c(-c3ccc(F)cn3)noc2C)nc1 CHEMBL3681577 Ki 2.0 nM
Clc1ccc2c(c1)-c1ncnn1Cc1c(Cl)ncn1-2 CHEMBL1077391 Ki 2.0 nM
CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1 CHEMBL49141 Ki 2.0 nM
CCOC(=O)c1ncn2c1c(=O)n(Cc1cccnc1)c1cccc(Cl)c12 CHEMBL5279431 Ki 2.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676483 Ki 2.1 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681423 Ki 2.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2(O)CC2)cn1 CHEMBL3681496 Ki 2.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3676464 Ki 2.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCCO)cn1 CHEMBL3681519 Ki 2.2 nM
Cn1ncnc1COc1nn2c(-c3cc(F)ccc3F)nnc2cc1C(C)(C)C CHEMBL373250 Ki 2.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCC(C)O)cn1 CHEMBL3681515 Ki 2.3 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3676540 Ki 2.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(O)C(F)(F)F)cn1 CHEMBL3681488 Ki 2.3 nM
Cc1onc(-c2ccc(F)cc2F)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681561 Ki 2.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(C)(C)O)cn1 CHEMBL3681495 Ki 2.3 nM
CC[C@H](CO)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681509 Ki 2.3 nM
Cc1onc(-c2ccc(F)cc2F)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681560 Ki 2.4 nM
Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681432 Ki 2.4 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(C)O)cn1 CHEMBL3676466 Ki 2.5 nM
CCOC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1cc(C#C[Si](C)(C)C)ccc1-2 CHEMBL130416 Kd 2.6 nM
Cc1nc(/C=C/c2c(C)nnn2-c2ccc(F)cc2)sc1C(=O)NC1CCOCC1 CHEMBL3675681 Ki 2.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCO)cn1 CHEMBL3676465 Ki 2.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCCCO)cn1 CHEMBL3681520 Ki 2.6 nM
CCCC(=O)N(C)Cc1c(-c2ccc(Cl)cc2)nc2ccccn12 CHEMBL73416 IC50 2.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3676479 Ki 2.7 nM
Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681430 Ki 2.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H]2CCC[C@H]2O)cn1 CHEMBL3681511 Ki 2.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H]2CCCC[C@H]2O)cn1 CHEMBL3676429 Ki 2.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCc2nc(C#N)cs2)cn1 CHEMBL3676473 Ki 2.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCC2)cn1 CHEMBL3676480 Ki 2.8 nM
Cc1onc(-c2ccc(Cl)cc2)c1CNc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676451 Ki 2.9 nM
CCNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3676461 Ki 2.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2(C#N)CC2)cn1 CHEMBL3681540 Ki 2.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCCC2O)cn1 CHEMBL3681494 Ki 2.9 nM
Cc1cc(C(=O)NC(C)C)cnc1OCc1c(-c2ccccc2)noc1C CHEMBL3676519 Ki 2.95 nM
CN1C(=O)CN=C(c2ccccc2F)c2cc([N+](=O)[O-])ccc21 CHEMBL13280 Kd 3.0 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3676538 Ki 3.0 nM
Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681590 Ki 3.0 nM
CCOC(=O)c1nc(C)c2[nH]c3cc(OC)c(OC)cc3c2c1CC CHEMBL5275690 Ki 3.0 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(N=[N+]=[N-])ccc1-2 CHEMBL6597 Ki 3.1 nM
Cc1cccc(OCc2c(-c3ccccc3)noc2C)n1 CHEMBL3676454 Ki 3.1 nM
Cc1cccc(-c2noc(C)c2COc2ccc(C(=O)NC(C)C)cn2)c1 CHEMBL3681547 Ki 3.1 nM
CCNC(=O)c1ccc(OCc2c(-c3ccncn3)noc2C)nc1 CHEMBL3681594 Ki 3.1 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3676539 Ki 3.2 nM
Cc1cccc(-c2noc(C)c2COc2ccc(C(=O)NC3CCOCC3)cn2)c1 CHEMBL3681546 Ki 3.2 nM
Cc1noc(-c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)n1 CHEMBL3681542 Ki 3.3 nM
Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NCC(C)(C)CO)cn1 CHEMBL3681565 Ki 3.3 nM
Cc1onc(-c2ccccc2F)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3676536 Ki 3.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2(C)CC2)cn1 CHEMBL3681536 Ki 3.6 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681479 Ki 3.7 nM
Cc1onc(-c2ccc(Cl)cn2)c1COc1ccc(C(=O)O)cn1 CHEMBL3681581 Ki 3.8 nM
COC(=O)c1ccc(OCc2c(-c3ccccn3)noc2C)nc1 CHEMBL3681568 Ki 3.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3676468 Ki 3.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCC2)cn1 CHEMBL3676481 Ki 3.9 nM
Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676550 Ki 3.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCC2O)cn1 CHEMBL3681500 Ki 3.9 nM
Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2 CHEMBL646 Kd 4.0 nM
CCOC(=O)c1ncn2c1C1CCCN1C(=O)c1cc(C#C[Si](C)(C)C)ccc1-2 CHEMBL518197 Kd 4.0 nM
Cc1onc(C2CCCCN2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 CHEMBL3676432 Ki 4.0 nM
CC(=O)NCCNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681505 Ki 4.0 nM
CCOC(=O)c1ncc2[nH]c3ccc(OC)cc3c2c1COC CHEMBL5280240 Ki 4.0 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3681452 Ki 4.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCCCCO)cn1 CHEMBL3681521 Ki 4.1 nM
Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3681579 Ki 4.1 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 CHEMBL3681551 Ki 4.1 nM
CNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3676460 Ki 4.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCN2CCNC2=O)cn1 CHEMBL3681514 Ki 4.3 nM
Cc1onc(-c2cc(F)ccc2F)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681563 Ki 4.3 nM
C[C@@H](CO)NC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681631 Ki 4.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCF)cn1 CHEMBL3676462 Ki 4.4 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H]2CCCC[C@H]2O)cn1 CHEMBL3681504 Ki 4.4 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3681419 Ki 4.4 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681454 Ki 4.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CN(C(=O)OC(C)(C)C)C2)cn1 CHEMBL3681516 Ki 4.5 nM
Cc1onc(-c2ccccc2F)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3676534 Ki 4.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCS(=O)(=O)C2)cn1 CHEMBL3639803 Ki 4.5 nM
COC(=O)c1ccc(OCc2c(-c3ccc(Cl)cc3)noc2C)nc1 CHEMBL3681421 Ki 4.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCc2ccccn2)cn1 CHEMBL3676474 Ki 4.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CCOC2)cn1 CHEMBL3676527 Ki 4.6 nM
Cc1onc(-c2ccccc2F)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676537 Ki 4.6 nM
FC(F)c1ncn2c1Cn1ncnc1-c1cc(Br)ccc1-2 CHEMBL1080588 Ki 4.6 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)OC(C)C)cn1 CHEMBL3676533 Ki 4.7 nM
Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681431 Ki 4.7 nM
CNC(=O)c1ccc(OCc2c(-c3ccncn3)noc2C)nc1 CHEMBL3681595 Ki 4.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H]2CCCC[C@@H]2O)cn1 CHEMBL3681503 Ki 4.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCS(=O)(=O)CC2)cn1 CHEMBL3676485 Ki 4.9 nM
CCOC(=O)c1ncn2c3ccc(C#C[Si](C)(C)C)cc3c(=O)n(C)c12 CHEMBL461716 Kd 5.0 nM
COc1ccc(-n2[nH]c3c(cnc4ccccc43)c2=O)cc1 CHEMBL3144739 Kd 5.0 nM
CCN1CCCC(NC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)C1 CHEMBL3676491 Ki 5.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CC(O)C2)cn1 CHEMBL3681493 Ki 5.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H]2CCC[C@@H]2O)cn1 CHEMBL3681510 Ki 5.0 nM
CCOC(=O)c1ncc2[nH]c3ccc(OCc4ccccc4)cc3c2c1COC CHEMBL1518572 Ki 5.0 nM
COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12 CHEMBL454095 Ki 5.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2ccn(C)n2)cn1 CHEMBL3681541 Ki 5.1 nM
COCCCNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3676467 Ki 5.2 nM
Cc1onc(-c2cccc(F)c2F)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681559 Ki 5.2 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3681428 Ki 5.4 nM
O=C(NC(CO)CO)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681629 Ki 5.5 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681455 Ki 5.6 nM
Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681591 Ki 5.6 nM
CC(C)NC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681620 Ki 5.6 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681451 Ki 5.9 nM
Cc1onc(-c2ccccc2)c1CNc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681469 Ki 5.9 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681477 Ki 5.9 nM
Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)NCCO)cn1 CHEMBL3681597 Ki 6.0 nM
COCc1ncn2c1CN(C)C(=O)c1cc(Cl)ccc1-2 CHEMBL45346 Ki 6.0 nM
Cc1nc(/C=C/c2c(-c3ccc(F)cc3)nnn2C)sc1C(=O)NC1CCOCC1 CHEMBL3675680 Ki 6.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCN(C)CC2)cn1 CHEMBL3676486 Ki 6.3 nM
O=C(NC1CCOCC1)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681621 Ki 6.4 nM
Cc1cc(CNC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)c(=O)[nH]n1 CHEMBL3676475 Ki 6.5 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681481 Ki 6.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H]2CCCC[C@@H]2O)cn1 CHEMBL3681499 Ki 6.5 nM
Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NCC(C)(C)O)cn1 CHEMBL3681566 Ki 6.7 nM
CC(C)NC(=O)c1ccc(OCc2conc2C2CCC(F)CN2)nc1 CHEMBL3676440 Ki 6.8 nM
Cc1nc(/C=C/c2c(C)nnn2-c2ccc(F)cc2)sc1C(=O)NC(C)C CHEMBL3675682 Ki 6.8 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3681575 Ki 6.8 nM
C#Cc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2C CHEMBL174535 Kd 7.0 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681453 Ki 7.1 nM
CC(O)CNC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681623 Ki 7.1 nM
COC(=O)C(=O)Nc1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681483 Ki 7.2 nM
CC(C)NC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681600 Ki 7.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCN(Cc3ccccc3)CC2)cn1 CHEMBL3676489 Ki 7.3 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681480 Ki 7.4 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3681429 Ki 7.5 nM
Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3676549 Ki 7.6 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3681478 Ki 7.6 nM
CCC(CC)CNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3676469 Ki 7.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(C)(C)CO)cn1 CHEMBL3681490 Ki 7.7 nM
Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3676547 Ki 7.8 nM
COCCNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681487 Ki 7.8 nM
Cc1c(F)c(Nc2ccc(-c3cn(C)cn3)cn2)cc2c1ncn2CC1CC1 CHEMBL4581355 Ki 7.9 nM
O=C(NC1CCOCC1)c1ccc(OCc2conc2C2CCC(F)CN2)nc1 CHEMBL3676439 Ki 8.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCOC(C)(C)C2)cn1 CHEMBL3676484 Ki 8.0 nM
O=C(N[C@H]1CCC[C@@H]1O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681628 Ki 8.0 nM
O=C(NCC(F)(F)F)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3686274 Ki 8.0 nM
Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 CHEMBL3681592 Ki 8.1 nM
Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3676548 Ki 8.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCCCCCO)cn1 CHEMBL3681522 Ki 8.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCNC(=O)OC(C)(C)C)cn1 CHEMBL3681517 Ki 8.4 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)NCCO)C2)cn1 CHEMBL3676497 Ki 8.4 nM
Cc1onc(-c2ccccc2)c1CNc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681471 Ki 8.8 nM
CC(CO)NC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681602 Ki 9.0 nM
Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 CHEMBL3681564 Ki 9.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)O)C2)cn1 CHEMBL3676493 Ki 9.3 nM
NC(=O)c1ccc(C(OCc2conc2-c2ccc(F)cn2)C(F)(F)F)nc1 CHEMBL3686278 Ki 9.3 nM
CCN1CCC(NC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)CC1 CHEMBL3676487 Ki 9.4 nM
CC(=O)Nc1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681482 Ki 9.4 nM
C[C@@H](O)CNC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681614 Ki 9.5 nM
Cn1c(=O)c2cc(Cl)ccc2n2cnc(C(=O)OCC3CC3)c12 CHEMBL458319 Ki 9.8 nM
Cc1onc(-c2ccccc2F)c1COc1ccc(C(=O)NCC(F)(F)C(F)(F)F)cn1 CHEMBL3676535 Ki 9.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCN(C(C)C)CC2)cn1 CHEMBL3676488 Ki 9.9 nM
Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2 CHEMBL661 EC50 10.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 CHEMBL3681486 Ki 10.0 nM
CCOC(=O)c1ncc2[nH]c3ccccc3c2c1COC CHEMBL5266498 Ki 10.0 nM
Cc1onc(C2CCCCN2)c1CNc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676452 Ki 10.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(NC(=O)C2CC2)cn1 CHEMBL3681485 Ki 10.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)NCC(F)(F)F)C2)cn1 CHEMBL3676496 Ki 10.1 nM
O=C(NCCCO)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681624 Ki 10.3 nM
Cc1onc(-c2ccccc2)c1CNc1ccc(C(=O)NCCO)cn1 CHEMBL3681467 Ki 10.4 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3681418 Ki 10.4 nM
Cc1onc(-c2ccccc2)c1CNc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681470 Ki 10.6 nM
O=C(NC1CCOCC1)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681601 Ki 10.6 nM
Cc1onc(-c2ccccc2)c1COc1cc(C(F)(F)F)c(C(=O)NC2CCOCC2)cn1 CHEMBL3676513 Ki 10.7 nM
C[C@H](CO)NC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681630 Ki 10.7 nM
O=C(NCCO)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681622 Ki 10.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@H](CO)CC(C)C)cn1 CHEMBL3681507 Ki 10.9 nM
O=c1c2cncn2c2ccc(Cl)cc2n1Cc1cccnc1 CHEMBL5276178 Ki 11.0 nM
Cc1nc(/C=C/c2c(-c3ccc(F)cc3)nnn2C)sc1C(=O)NC(C)C CHEMBL3675679 Ki 11.3 nM
COC(=O)c1ccc(OCc2c(-c3ccncn3)noc2C)nc1 CHEMBL3681589 Ki 11.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CCCOC2)cn1 CHEMBL3676526 Ki 11.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)(C)C)cn1 CHEMBL3676499 Ki 11.8 nM
O=c1c2c(Cl)ncn2c2ccccc2n1Cc1ccccn1 CHEMBL5267248 Ki 12.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2ccc(F)cc2)cn1 CHEMBL3676501 Ki 12.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)NC3CC3)C2)cn1 CHEMBL3676495 Ki 12.3 nM
O=C(NC1CC1)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681619 Ki 12.4 nM
O=C(NC1CCOCC1)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681449 Ki 12.5 nM
Cc1nc(/C=C/c2c(-c3ccccn3)nnn2C)sc1C(=O)NC1CCOCC1 CHEMBL3675684 Ki 12.7 nM
O=C(NC1CC1)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681606 Ki 12.9 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3681417 Ki 13.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C#N)cn1 CHEMBL3676457 Ki 13.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCc2nc(C3CC3)no2)cn1 CHEMBL3676471 Ki 13.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCCC2)cn1 CHEMBL3676482 Ki 13.1 nM
O=C(NCC(O)C(F)(F)F)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681610 Ki 13.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)NC3CCOCC3)C2)cn1 CHEMBL3676498 Ki 13.1 nM
CC(=O)NCCNC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681632 Ki 13.1 nM
CC(C)NC(=O)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3686271 Ki 13.1 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676545 Ki 13.4 nM
O=C(NC1CC1)c1ccc(OCc2conc2C2CCC(F)CN2)nc1 CHEMBL3676441 Ki 13.5 nM
CCNC(=O)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3686276 Ki 13.6 nM
CCNC(=O)CN1CCCC(NC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)C1 CHEMBL3676494 Ki 13.7 nM
CCOC(=O)CN1CCCC(NC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)C1 CHEMBL3676492 Ki 13.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC2)cn1 CHEMBL3681537 Ki 13.9 nM
C[C@@H](CO)NC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681604 Ki 13.9 nM
CCNC(=O)c1ccc(OCc2conc2C2CCC(F)CN2)nc1 CHEMBL3676442 Ki 14.1 nM
COC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3676459 Ki 14.2 nM
Cc1onc(-c2ccccc2)c1COc1cc(C(F)(F)F)c(C(=O)NC(C)C)cn1 CHEMBL3676512 Ki 14.6 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3681571 Ki 14.6 nM
Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3676427 Ki 14.9 nM
CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc21 CHEMBL12 Ki 15.0 nM
O=c1c2cncn2c2ccccc2n1Cc1cncnc1 CHEMBL5267241 Ki 15.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CC3(COC3)C2)cn1 CHEMBL3676531 Ki 15.1 nM
O=C(NCC(F)(F)F)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681607 Ki 15.1 nM
O=C(NCC(F)(F)F)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681618 Ki 15.1 nM
Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681474 Ki 15.4 nM
Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2CCOCC2)n(C)n1 CHEMBL3675676 Ki 15.7 nM
COC1CN(C(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)C1 CHEMBL3681538 Ki 16.0 nM
Cc1ccc(Cn2c(=O)c3cncn3c3ccccc32)cn1 CHEMBL5283624 Ki 16.0 nM
COC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C)nc1 CHEMBL3676552 Ki 16.2 nM
O=C(NCCO)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681444 Ki 16.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC23COC3)cn1 CHEMBL3676532 Ki 16.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC(F)(F)CC2)cn1 CHEMBL3676504 Ki 16.8 nM
Cc1ccncc1Cn1c(=O)c2cncn2c2ccccc21 CHEMBL5281879 Ki 17.0 nM
Cc1cncc(Cn2c(=O)c3cncn3c3ccccc32)c1 CHEMBL5282000 Ki 17.0 nM
COC(=O)c1ccc(OCc2c(-c3cccc(F)c3)noc2C)nc1 CHEMBL3639754 Ki 17.4 nM
O=C(NCC1CC1)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681605 Ki 17.4 nM
CSc1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681544 Ki 17.7 nM
O=C(NC1CCOCC1)c1ccc(OCc2conc2-c2ccccc2)nc1 CHEMBL3681599 Ki 17.7 nM
Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681473 Ki 17.8 nM
O=C(N[C@H]1CCC[C@@H]1O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681608 Ki 17.8 nM
O=C(NC1CCOCC1)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3681634 Ki 17.8 nM
Cc1ncn2c1c(=O)n(Cc1cccnc1)c1ccccc12 CHEMBL5279584 Ki 18.0 nM
Cc1onc(-c2ccccc2)c1COc1cc(C(F)(F)F)c(C(=O)O)cn1 CHEMBL3676511 Ki 18.4 nM
NC(=O)c1ccc(COCc2conc2-c2ccc(F)cn2)nc1 CHEMBL3686280 Ki 18.5 nM
Cc1onc(-c2ccccc2)c1COc1ncc(C(=O)NC(C)C)cc1Br CHEMBL3676518 Ki 18.6 nM
O=C(NC1CC1)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3686272 Ki 18.9 nM
O=C(NCC1CC1)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3686273 Ki 19.0 nM
CCOC(=O)c1ncc2[nH]c3ccc(O)cc3c2c1COC CHEMBL5290464 Ki 19.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(NC(=O)C(C)C)cn1 CHEMBL3681484 Ki 19.2 nM
Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)O)cn1 CHEMBL3681578 Ki 19.2 nM
CCOC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1C CHEMBL3676522 Ki 19.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CC(=O)NO2)cn1 CHEMBL3676470 Ki 19.4 nM
Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681475 Ki 19.4 nM
O=C(NC1CCS(=O)(=O)C1)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681617 Ki 19.4 nM
Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676551 Ki 19.5 nM
CNC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681442 Ki 19.8 nM
O=C(NCCO)c1ccc(OCc2conc2-c2ccccn2)nc1 CHEMBL3686275 Ki 19.9 nM
C[C@H](NC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1)C(F)(F)F CHEMBL3681633 Ki 20.0 nM
COc1ccc2c(c1)n(Cc1cccnc1)c(=O)c1cncn12 CHEMBL5276982 Ki 20.0 nM
Cc1onc(C2CCCNC2)c1COc1ccc(C(=O)N2CCC[C@H]2CO)cn1 CHEMBL3676446 Ki 20.2 nM
CCOC(=O)C(C)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3676477 Ki 20.2 nM
Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3681596 Ki 20.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N(C)C2CCOCC2)cn1 CHEMBL3676502 Ki 20.2 nM
Cc1nc(/C=C/c2c(-c3ccccn3)nnn2C)sc1C(=O)NC(C)C CHEMBL3675683 Ki 20.7 nM
Cc1onc(-c2ccccc2)c1COc1cccc(C#N)n1 CHEMBL3676523 Ki 20.9 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C2(O)COC2)cn1 CHEMBL3681420 Ki 20.9 nM
O=C(NC(CO)CO)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681611 Ki 21.2 nM
CC(C)NC(=O)c1ccc(OCc2conc2-c2ccccc2)nc1 CHEMBL3681598 Ki 21.4 nM
NC(=O)c1ccc(CC(O)OCc2conc2-c2ccc(F)cn2)nc1 CHEMBL3686279 Ki 21.4 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCc2cc(C3CC3)[nH]n2)cn1 CHEMBL3676472 Ki 21.6 nM
O=C(NC1CCOCC1)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681440 Ki 22.1 nM
Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)NN2CCOCC2)n(C)n1 CHEMBL3675677 Ki 22.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc([N+](=O)[O-])cn1 CHEMBL3676458 Ki 22.2 nM
Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)O)cn1 CHEMBL3681422 Ki 22.3 nM
Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)O)cn1 CHEMBL3681576 Ki 22.3 nM
O=C(NCC1CC1)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681446 Ki 22.5 nM
O=C(N[C@@H]1CCC[C@H]1O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681609 Ki 22.6 nM
Cc1onc(C2CCCNC2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676443 Ki 22.8 nM
CC(C)(CO)CNC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681626 Ki 22.9 nM
O=C(NCC1(O)CC1)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681616 Ki 23.1 nM
O=C(NCCO)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681615 Ki 23.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3676505 Ki 23.6 nM
O=C(NC1CC1)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681439 Ki 23.8 nM
Cc1onc(-c2cccnc2)c1COc1ccc(C(=O)NCC(F)(F)F)cn1 CHEMBL3681460 Ki 24.0 nM
CNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681434 Ki 24.3 nM
Cc1onc(-c2ccccc2)c1COc1ncc(C(=O)NC2CCOCC2)cc1Br CHEMBL3676515 Ki 24.4 nM
[O-][n+]1nc2c(I)cnn2c2cc(NCc3cccnc3)ccc21 CHEMBL2348441 Ki 24.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3676506 Ki 25.6 nM
COC(=O)c1ccc(NCc2c(-c3ccc(F)cc3)noc2C)nc1 CHEMBL3681476 Ki 25.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC(O)C2)cn1 CHEMBL3681523 Ki 26.1 nM
Cc1onc(-c2cccnc2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3681462 Ki 26.3 nM
Cc1onc(-c2cccc(F)c2F)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681558 Ki 26.5 nM
CCOC(=O)c1cc2c3ccccc3nc-2c[nH]1 CHEMBL11709 Kd 27.0 nM
CCOC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL454606 Ki 27.0 nM
Cc1onc(-c2cc(F)ccc2F)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681562 Ki 27.3 nM
COC(=O)c1ccc(NCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681466 Ki 27.4 nM
COC(=O)c1ccc(OCc2c(-c3cccc(Cl)c3)noc2C)nc1 CHEMBL3676546 Ki 27.4 nM
C[C@H](CO)NC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681603 Ki 27.7 nM
Cc1onc(-c2cccnc2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 CHEMBL3681464 Ki 27.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)O)cn1 CHEMBL3681528 Ki 28.0 nM
O=c1c2cncn2c2ccccc2n1Cc1cccnc1 CHEMBL5271002 Ki 28.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C2(O)COC2)cn1 CHEMBL3676524 Ki 28.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc([S+](C)[O-])cn1 CHEMBL3681545 Ki 28.1 nM
O=C(NCC1CC1)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681437 Ki 28.3 nM
Cn1nnc(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2CCOCC2)on1 CHEMBL3675674 Ki 28.8 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N[C@@H]2CCC[C@@H]2O)cn1 CHEMBL3676428 Ki 29.2 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3676449 Ki 29.2 nM
Cc1onc(-c2cccnc2)c1COc1ccc(C(=O)NCC2CC2)cn1 CHEMBL3681461 Ki 29.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCn3cnnc3C2)cn1 CHEMBL3676525 Ki 29.9 nM
Cc1cc(Cn2c(=O)c3c(C)ncn3c3ccccc32)no1 CHEMBL5290343 Ki 30.0 nM
CCNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681435 Ki 30.8 nM
Cc1onc(-c2ccccc2)c1COc1ccc(Br)cn1 CHEMBL3676455 Ki 31.1 nM
Cc1onc(-c2cccnc2)c1COc1ccc(C(=O)NC(C)C)cn1 CHEMBL3681463 Ki 31.7 nM
Cc1onc(-c2ccccc2)c1COc1cc(C2=CCN(C)CC2)ccn1 CHEMBL3676444 Ki 32.1 nM
CCCCS(=O)(=O)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681530 Ki 32.2 nM
O=c1c2cncn2c2ccccc2n1Cc1cnccn1 CHEMBL5287850 Ki 33.0 nM
Cc1csc(-c2cc(-c3ccncc3)c3n(c2=O)CCCc2ccncc2-3)n1 CHEMBL45198 Ki 33.3 nM
CCNC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681443 Ki 33.3 nM
CC(C)NC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681447 Ki 33.5 nM
O=C(NCCO)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681436 Ki 34.0 nM
COC(=O)c1cnc(OCc2c(-c3ccccc3)noc2C)c(Br)c1 CHEMBL3676514 Ki 34.4 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)n2ccc(=O)[nH]2)cn1 CHEMBL3681535 Ki 34.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(=O)OC(C)(C)C)cn1 CHEMBL3676476 Ki 35.0 nM
Cc1onc(-c2ccccc2)c1COc1cc(OCc2ccccc2)ccn1 CHEMBL3676507 Ki 35.1 nM
Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3681593 Ki 36.2 nM
Cc1onc(-c2ccccc2)c1COc1ccccn1 CHEMBL3676453 Ki 36.5 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N(C)S(=O)(=O)C2CC2)cn1 CHEMBL3681533 Ki 36.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCCC2)cn1 CHEMBL3681526 Ki 37.1 nM
Cc1onc(-c2ccccc2)c1CNc1ccc(C(=O)NCCN2CCCC2=O)cn1 CHEMBL3681468 Ki 37.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCSC2)cn1 CHEMBL3681539 Ki 37.3 nM
CC(=O)NCCNC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681612 Ki 37.6 nM
Cc1onc(-c2ccccc2)c1COc1cc(C(=O)NCC(F)(F)F)ccn1 CHEMBL3676508 Ki 37.8 nM
O=C(c1cccc(F)c1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL356806 EC50 38.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2ccccc2)cn1 CHEMBL3676500 Ki 38.0 nM
O=C(NC1CC1)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681448 Ki 38.4 nM
Cc1nc(OCc2c(-c3ccccc3)noc2C)ccc1C(=O)NC1CCOCC1 CHEMBL3676510 Ki 38.7 nM
Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)O)cn1 CHEMBL3676553 Ki 39.5 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3681457 Ki 39.7 nM
CC(C)(CO)NC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 CHEMBL3681625 Ki 39.9 nM
O=C1C2C=Nc3ccccc3C2=NN1c1ccc(Cl)cc1 CHEMBL20042 Kd 40.0 nM
c1ccc2c(c1)[nH]c1c2ncc2[nH]c3ccccc3c21 CHEMBL301605 Ki 40.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCCn3nccc32)cn1 CHEMBL3676528 Ki 40.7 nM
COCCNC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 CHEMBL3681613 Ki 40.7 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NC2CC2)cn1 CHEMBL3676541 Ki 41.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCOC(C)C)cn1 CHEMBL3681491 Ki 41.3 nM
CC(C)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681438 Ki 41.6 nM
Cc1onc(C2CCCNC2)c1COc1ccc(C(=O)N2CCC[C@@H]2CO)cn1 CHEMBL3676445 Ki 41.9 nM
Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)N2CC3CC(C2)O3)cn1 CHEMBL3676450 Ki 42.6 nM
Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2(C)COC2)n(C)n1 CHEMBL3675678 Ki 43.2 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(C(=O)OC(C)(C)C)C2)cn1 CHEMBL3676490 Ki 43.5 nM
COC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL453066 Ki 44.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCc2cc(C(C)C)no2)cn1 CHEMBL3676530 Ki 44.4 nM
CC(C)(c1ccc(C(N)=O)cn1)C(O)OCc1conc1-c1ccc(F)cn1 CHEMBL3686277 Ki 44.9 nM
Cn1nc(OCc2c(-c3ccc(F)cc3)nnn2C)cc1C(=O)NC1CCOCC1 CHEMBL3675675 Ki 45.3 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)N2CCSCC2)cn1 CHEMBL3676544 Ki 45.6 nM
Cc1nc(OCc2c(-c3ccccc3)noc2C)c(Br)cc1C(=O)NC1CCOCC1 CHEMBL3676517 Ki 47.3 nM
COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 CHEMBL3681527 Ki 47.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCCC2C)cn1 CHEMBL3681525 Ki 48.0 nM
CN1C(=O)COc2cc(Cn3c(=O)c4cncn4c4ccccc43)ccc21 CHEMBL5285035 Ki 48.0 nM
Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3676543 Ki 48.1 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCCCC2)cn1 CHEMBL3676503 Ki 50.8 nM
O=c1c2c(CO)ncn2c2ccccc2n1Cc1cccnc1 CHEMBL5287391 Ki 52.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N(C)C(C)C)cn1 CHEMBL3676520 Ki 53.1 nM
COC(=O)c1ccc(OCc2c(-c3cccnc3)noc2C)nc1 CHEMBL3681459 Ki 53.2 nM
C#Cc1ccc2c(c1)C(c1ccccc1F)=N[C@H](C)c1c(C(=O)NC)ncn1-2 CHEMBL4228824 Ki 55.0 nM
Cc1onc(-c2ccccc2)c1COc1cc(C(=O)NC2CCOCC2)ccn1 CHEMBL3676509 Ki 55.4 nM
CC(C)(C)OC(=O)N1CC(NC(=O)c2ccc(OCc3conc3-c3ccc(Cl)cc3)nc2)C1 CHEMBL3681627 Ki 55.5 nM
Cc1cc(Cn2c(=O)c3cncn3c3ccccc32)no1 CHEMBL5266848 Ki 56.0 nM
COC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681441 Ki 57.0 nM
O=C(NCC(F)(F)F)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 CHEMBL3681445 Ki 57.8 nM
Cn1c(=O)c2cc(C#C[Si](C)(C)C)ccc2n2cnc(C(=O)OC(C)(C)C)c12 CHEMBL461717 Kd 58.0 nM
O=C(c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1)N1CCS(=O)(=O)CC1 CHEMBL3681450 Ki 58.9 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(F)(F)F)cn1 CHEMBL3676456 Ki 60.8 nM
Cn1cc(Cn2c(=O)c3cncn3c3ccccc32)cn1 CHEMBL5283694 Ki 64.0 nM
Cc1ncn2c1c(=O)n(Cc1ccccn1)c1ccccc12 CHEMBL5285179 Ki 65.0 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 CHEMBL3681458 Ki 65.7 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2COCc3ccccc32)cn1 CHEMBL3676529 Ki 68.1 nM
COC(=O)c1ccc(NCc2c(-c3cccc(F)c3)noc2C)nc1 CHEMBL3681472 Ki 69.3 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC(O)CC2)cn1 CHEMBL3681489 Ki 73.4 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1ccccc1)CC2 CHEMBL356161 EC50 74.0 nM
C#Cc1ccc2c(c1)C(c1ccccc1F)=N[C@H](C)c1c(C(=O)NC3CC3)ncn1-2 CHEMBL4553352 Ki 79.0 nM
O=c1c2c(CC3CC3)ncn2c2ccccc2n1Cc1ccccn1 CHEMBL5289385 Ki 80.0 nM
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCOCC2(C)C)cn1 CHEMBL3676521 Ki 80.8 nM
CCOCc1ncn2c3ccc(Cl)cc3c(=O)n(C)c12 CHEMBL459031 Ki 83.0 nM
Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 CHEMBL3681456 Ki 84.5 nM
Cc1cccc2c1n1cncc1c(=O)n2Cc1cccnc1 CHEMBL5272704 Ki 86.0 nM
Cc1onc(-c2ccccc2)c1CNc1ccccn1 CHEMBL3681465 Ki 87.3 nM
COC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 CHEMBL3681433 Ki 88.5 nM
O=c1c2cncn2c2ccc(Br)cc2n1Cc1cccnc1 CHEMBL5284313 Ki 89.0 nM
Cc1ccc(C(=O)N2CCc3nc(O)n4cc(-c5ccccc5F)nc4c3C2)cc1 CHEMBL343471 EC50 90.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(CC1CC1)CC2 CHEMBL145970 EC50 94.0 nM
CC1=NN=C(c2cc3ccc(F)cc3s2)c2cc3oc(=O)[nH]c3cc2C1 CHEMBL3652873 IC50 100.0 nM
Cc1ncccc1Cn1c(=O)c2cncn2c2ccccc21 CHEMBL5290905 Ki 107.0 nM
CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL509197 Ki 110.0 nM
Cc1ccccc1C(=O)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL344120 EC50 111.0 nM
CC(C)(C)OC(=O)c1cc2c3ccccc3nc-2c[nH]1 CHEMBL307783 Kd 111.0 nM
COc1ccc(C(=O)N2CCc3nc(O)n4cc(-c5ccccc5F)nc4c3C2)cc1 CHEMBL146317 EC50 112.0 nM
O=c1c2cncn2c2cccnc2n1Cc1cccnc1 CHEMBL5278670 Ki 122.0 nM
CC1=NN=C(c2cc3ccccc3s2)c2cc3oc(=O)[nH]c3cc2C1 CHEMBL3652869 IC50 130.0 nM
O=c1c2cncn2c2ccccc2n1Cc1ccccn1 CHEMBL5272593 Ki 132.0 nM
O=c1c2cncn2c2c(Cl)cc(Cl)cc2n1Cc1cccnc1 CHEMBL5275441 Ki 138.0 nM
COc1cc(Cl)c2c(c1)n(Cc1cccnc1)c(=O)c1cncn12 CHEMBL5276966 Ki 142.0 nM
CCCCC(=O)c1ncn2c3ccc(Cl)cc3c(=O)n(C)c12 CHEMBL511685 Ki 166.0 nM
CCc1ncn2c3ccc(Cl)cc3c(=O)n(C)c12 CHEMBL458321 Ki 182.0 nM
O=C1C2C=Nc3ccccc3C2=NN1c1ccccc1 CHEMBL19732 Kd 200.0 nM
CC1=NN=C(c2cc3c(F)cccc3s2)c2cc3oc(=O)[nH]c3cc2C1 CHEMBL3652871 IC50 200.0 nM
c1ccc2c(c1)[nH]c1cnc3c4cccnc4[nH]c3c12 CHEMBL2008708 Ki 200.0 nM
CC1=NN=C(c2cc3c(C(F)(F)F)cccc3s2)c2cc3oc(=O)[nH]c3cc2C1 CHEMBL3652872 IC50 201.0 nM
CSC1SC(C(=O)c2ccc(Cl)cc2)C2CC(C)(C)CC(=O)C12 CHEMBL458144 IC50 210.0 nM
C#Cc1ccc2[nH]c3cnc(C(=O)OC(C)(C)C)cc3c2c1 CHEMBL1270038 Ki 210.0 nM
Clc1ccc2c(c1)[nH]c1c2ncc2[nH]c3ccccc3c21 CHEMBL496990 Ki 210.0 nM
CC(C)(C)c1ccc2c(c1)n(Cc1cccnc1)c(=O)c1cncn12 CHEMBL5281265 Ki 210.0 nM
CCCNC(=O)c1nnc2c(-c3c(F)cccc3OC)cccc2c1N CHEMBL1783282 Ki 230.0 nM
COc1ccc2c(c1)[nH]c1c2ncc2[nH]c3ccccc3c21 CHEMBL497197 Ki 230.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(CC1CCCCC1)CC2 CHEMBL146230 EC50 231.0 nM
c1ccc2c(c1)[nH]c1cnc3c4ccncc4[nH]c3c12 CHEMBL5281056 Ki 240.0 nM
COc1ccc(Cn2c(=O)c3cncn3c3ccccc32)cc1 CHEMBL5267297 Ki 244.0 nM
CC1=NN=C(c2sc3cccc(C(F)(F)F)c3c2Cl)c2cc3oc(=O)[nH]c3cc2C1 CHEMBL3652870 IC50 250.0 nM
CCCCN1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL147379 EC50 291.0 nM
O=c1c2cncn2c2c(Cl)cccc2n1Cc1cccnc1 CHEMBL5282970 Ki 295.0 nM
Oc1nc2c(c3nc(-c4ccc(F)cc4F)cn13)CN(Cc1ccccc1)CC2 CHEMBL343009 EC50 323.0 nM
O=C(c1ccccc1F)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL146302 EC50 346.0 nM
CCc1ncn2c1c(=O)n(Cc1ccccn1)c1ccccc12 CHEMBL5283190 Ki 360.0 nM
CCCCCc1ncn2c3ccc(Cl)cc3c(=O)n(C)c12 CHEMBL471115 Ki 369.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1cccs1)CC2 CHEMBL147364 EC50 375.0 nM
Cc1cc(Cc2ncn3c2c(=O)n(Cc2ccccn2)c2ccccc23)no1 CHEMBL5266379 Ki 379.0 nM
Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1c[nH]cn1)CC2 CHEMBL358874 EC50 439.0 nM
COC(=O)c1cc2c(cn1)[nH]c1ccc(NCc3ccccc3)cc12 CHEMBL5290746 Ki 480.0 nM
O=C(c1ccc(F)c(F)c1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL147590 EC50 491.0 nM
Cn1c(=O)c2cc(Cl)ccc2n2cnc(CCl)c12 CHEMBL461511 Ki 500.0 nM
CSC1SC(C(=O)c2ccc(Cl)cc2)C2CCCC(=O)C12 CHEMBL511684 IC50 550.0 nM
CCCOc1cc2c(cn1)[nH]c1ccccc12 CHEMBL499814 Ki 590.0 nM
CCCOc1cc2c3ccccc3nc-2c[nH]1 CHEMBL52750 Kd 591.0 nM
Cc1ccc(-c2cn3c(O)nc4c(c3n2)CN(Cc2ccccc2)CC4)cc1 CHEMBL147312 EC50 650.0 nM
COc1cc(Cl)c2c(c1)n(Cc1cnccc1C)c(=O)c1cncn12 CHEMBL5267056 Ki 687.0 nM
CCOc1cc2c3ccccc3nc-2c[nH]1 CHEMBL299250 Kd 826.0 nM
O=c1c2cncn2c2cc(Cl)ccc2n1Cc1cccnc1 CHEMBL5275509 Ki 840.0 nM
O=C(OCc1ccccc1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 CHEMBL146075 EC50 1000.0 nM
Nc1c(C(=O)c2ccc(Cl)cc2)sc2ccccc12 CHEMBL461925 IC50 1000.0 nM
CCCC(=O)c1cc2c(cn1)[nH]c1ccccc12 CHEMBL510764 Ki 1000.0 nM
CC(OC(=O)c1cc2c(cn1)[nH]c1ccccc12)c1ccccc1 CHEMBL1270841 Ki 1000.0 nM