CCOc1ccccc1NC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c1c(C)noc1C CHEMBL1612846 Potency 0.0316 nM
CCCCCCCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029773 Ki 0.4 nM
CCCCCCCCC[C@@H]1NC[C@@H](O)[C@H](O)[C@H]1CO CHEMBL5192083 IC50 0.6 nM
CC(F)[C@H]1CNC[C@@H](O)[C@@H]1O CHEMBL3684925 Ki 0.9 nM
CC1=CC(C)=[N+]2C1=C(CCCCc1cn(C[C@@H]3[C@@H](O)[C@H](O)[C@@H](O)[C@@H]4O[C@H]34)nn1)c1c(C)cc(C)n1[B-]2(F)F CHEMBL3692692 Ki 0.95 nM
CCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1OCCCCCCCCC CHEMBL2164231 Ki 1.0 nM
O[C@@H]1[C@@H](O)[C@@H](CCCCCOCC23CC4CC(CC(C4)C2)C3)NC[C@H]1O CHEMBL3289676 Ki 1.0 nM
CN(C)c1cccc2c(S(=O)(=O)NCCCCCCN(C)[C@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@H]3CO)cccc12 CHEMBL4080589 Ki 1.0 nM
CCN(CC)c1ccc2cc(C(=O)NC[C@H]3N[C@H](CO)[C@H](O)[C@@H]3O)c(=O)oc2c1 CHEMBL3350092 Ki 1.2 nM
CC(C)CCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029776 Activity 1.2 nM
O[C@@H]1[C@@H](O)[C@@H](CCSC2CCCCC2)NC[C@H]1O CHEMBL2029778 Activity 1.3 nM
COc1ccc(C2=[N+]3C(=C(CCCCc4cn(C[C@@H]5[C@@H](O)[C@H](O)[C@@H](O)[C@@H]6O[C@H]56)nn4)c4ccc(-c5ccc(OC)cc5)n4[B-]3(F)F)C=C2)cc1 CHEMBL3692694 Ki 1.56 nM
O[C@@H]1[C@@H](O)[C@@H](CCSCc2ccccc2)NC[C@H]1O CHEMBL2029779 Activity 1.6 nM
CCCCCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029772 Ki 1.8 nM
CN(C)c1cccc2c(S(=O)(=O)NCCCCCC(=O)NC[C@H]3N[C@H](CO)[C@H](O)[C@@H]3O)cccc12 CHEMBL3349997 Ki 2.1 nM
CCCCCCCCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL1091214 Ki 2.2 nM
CN(C)c1cccc2c(S(=O)(=O)NC[C@H]3N[C@H](CO)[C@H](O)[C@@H]3O)cccc12 CHEMBL3349996 Ki 2.4 nM
COc1cccc(NC(=S)N(CCCN2CCOCC2)Cc2cn(C)c3ccccc23)c1 CHEMBL1523867 Potency 2.5 nM
O[C@@H]1[C@@H](O)[C@@H](CCSCCc2ccccc2)NC[C@H]1O CHEMBL2029780 Activity 2.8 nM
O[C@H]1[C@H](O)CNC[C@@H]1C(F)F CHEMBL3684924 Ki 3.06 nM
CC(C)(C)c1ccc(C(=O)N2CCN(c3nc(N4CCCC4)nc4c3CCC4)CC2)cc1 CHEMBL5277174 IC50 3.7 nM
c1ccc2c(c1)CC(Nc1nc(-c3ccsc3)nc3ccccc13)C2 CHEMBL3976182 IC50 5.2 nM
O[C@@H]1[C@@H](O)[C@@H](CCSC2CCCC2)NC[C@H]1O CHEMBL2029777 Activity 5.3 nM
c1ccc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)cc1 CHEMBL3939100 IC50 6.5 nM
CC(C)(C)c1ccc(C(=O)N2CCN(c3nc(N4CCCC4)nc4c3CCCC4)CC2)cc1 CHEMBL5285901 IC50 6.5 nM
CCCCCCCCCC1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL5189151 IC50 6.8 nM
CN(C)c1cccc2c(S(=O)(=O)NC[C@H]3NC[C@@H](O)[C@H](O)[C@H]3O)cccc12 CHEMBL3289679 Ki 7.5 nM
COc1cc2c(cc1NC(=O)COC(=O)[C@@H](NC(=O)c1ccccc1)C(C)C)oc1ccccc12 CHEMBL1568014 Potency 7.9 nM
c1csc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3930102 IC50 8.2 nM
c1cncc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3923120 IC50 8.3 nM
c1cncc(-c2nc(N[C@H]3CCc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3950881 IC50 8.7 nM
O[C@@H]1[C@@H]([C@H](O)c2ccccc2)CNC[C@H]1O CHEMBL3684928 Ki 8.9 nM
CCCCCCO[C@H]1CNC[C@@H](O)[C@@H]1O CHEMBL3393682 IC50 9.0 nM
Cc1cc(N2CCN(C(=O)c3ccc(C(C)(C)C)cc3)CC2)nc(N2CCCC2)n1 CHEMBL5270898 EC50 9.6 nM
c1cncc(-c2nc(N[C@@H]3CCc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3923147 IC50 9.9 nM
CC(O)[C@H]1CNC[C@@H](O)[C@@H]1O CHEMBL3684926 Ki 10.0 nM
O=C(NCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O)Nc1ccccc1 CHEMBL2029782 Ki 12.0 nM
Cc1cncc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3976949 IC50 12.5 nM
OC[C@H]1CNC[C@@H](O)[C@@H]1O CHEMBL206468 Potency 12.6 nM
CC(C)(O)[C@H]1CNC[C@@H](O)[C@@H]1O CHEMBL3684929 Ki 15.0 nM
CCCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029771 Activity 18.0 nM
CCCCCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL1090540 IC50 19.0 nM
CCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1OC CHEMBL2164230 IC50 19.0 nM
OC[C@H]1CNC[C@@H](O)[C@@H]1O CHEMBL2105671 IC50 19.0 nM
CN(C)c1cccc2c(S(=O)(=O)NCCCCCCN[C@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@H]3CO)cccc12 CHEMBL4069909 Ki 19.0 nM
C[C@H]1CC[C@H](Nc2nc(-c3cccnc3)nc3ccccc23)CC1 CHEMBL3956777 IC50 20.0 nM
Cc1cc(N2CCOCC2)nc2ccc(NC(=O)C3CCCCC3)cc12 CHEMBL403714 Ki 21.0 nM
c1coc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3956552 IC50 21.1 nM
NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O CHEMBL3350086 Ki 25.0 nM
CCCCCCCCCN[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL2164227 IC50 25.0 nM
CCCCCCCCCN[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL2219816 IC50 25.0 nM
CCCCCCCCOC1OCC(CNC(=N)N2C[C@@H](O)[C@H](O)[C@@H](O)C2)O1 CHEMBL4278926 IC50 25.0 nM
CCCCCCCCCN[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1NCCCCCCCCC CHEMBL3216319 Ki 26.0 nM
c1cncc(-c2nc(NC3CCCCCCC3)c3ccccc3n2)c1 CHEMBL3964444 IC50 27.0 nM
CC(C)(C)SCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029775 Ki 29.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C)CC2)nc(N2CCCCCC2)n1 CHEMBL5266290 EC50 29.0 nM
Cc1ccc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)cn1 CHEMBL3968646 IC50 29.4 nM
CCCCCCCCCCCCn1cc(CN[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)nn1 CHEMBL1084109 IC50 30.0 nM
O=C(CSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O)NCc1ccccc1 CHEMBL2029783 Ki 30.0 nM
Cc1ccccc1C(=O)N1CCN(c2nc(N3CCCC3)nc3c2CCC3)CC1 CHEMBL5283935 EC50 30.0 nM
CC[C@@H](F)C1CNC[C@@H](O)[C@@H]1O CHEMBL3684930 Ki 31.0 nM
c1cncc(-c2nc(NC3COc4ccccc4C3)c3ccccc3n2)c1 CHEMBL3941104 IC50 35.0 nM
CSc1ccc(NC(=O)Nc2cc(C)ccn2)cc1 CHEMBL1408238 Potency 35.5 nM
CC(C)SCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029774 Activity 38.0 nM
Cc1cc(N2CCN(C(=O)c3ccc(Cl)cc3)CC2)nc(N2CCCC2)n1 CHEMBL5272738 EC50 40.0 nM
c1cncc(-c2nc(NC3CCCCCC3)c3ccccc3n2)c1 CHEMBL3974789 IC50 42.0 nM
O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1 CHEMBL1512531 Potency 44.7 nM
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](NCc2cn(Cc3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)nn2)[C@H](O)[C@H]1O CHEMBL1766350 IC50 50.0 nM
CCCCCCCCCCCn1cc(CN[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)nn1 CHEMBL1766482 Ki 50.0 nM
O=C(Nc1ccc(Oc2ccccc2)cc1)O/N=C1\N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CHEMBL3786789 Ki 50.0 nM
CCCCCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL450985 IC50 50.0 nM
CCc1nnc(NC(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)s1 CHEMBL406121 Ki 52.0 nM
CCCC1CCC(C(=O)Nc2ccc3nc(N4CCOCC4)cc(C)c3c2)CC1 CHEMBL259854 Ki 55.0 nM
Cc1cc(N2CCOCC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 CHEMBL259853 Ki 56.0 nM
CC1CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 CHEMBL3948124 IC50 56.0 nM
Cc1cc(N2CCN(C(=O)c3ccc(-c4ccccc4)cc3)CC2)nc(N2CCCC2)n1 CHEMBL5290073 EC50 58.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCCC12CC3CC(CC(C3)C1)C2 CHEMBL3354017 IC50 60.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3Cl)CC2)nc(N2CCCC2)n1 CHEMBL5276122 EC50 63.0 nM
O[C@@H]1[C@@H](Cc2ccccc2)CNC[C@H]1O CHEMBL3684927 Ki 67.0 nM
Cc1ccccc1-c1ccc(COCCCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)cc1 CHEMBL3354041 IC50 70.0 nM
Cc1ccc(C(=O)N2CCN(c3cc(C)nc(N4CCCC4)n3)CC2)cc1 CHEMBL5276663 EC50 70.0 nM
O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL2414884 Ki 71.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3)CC2)nc(N2CCCC2)n1 CHEMBL5291224 EC50 72.0 nM
O[C@@H]1c2c(C3CC3)n[nH]c2N[C@H](c2ccccc2Cl)[C@H]1n1nnc2ccccc21 CHEMBL5396941 IC50 74.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C)CC2)nc(N2CCCC2)n1 CHEMBL5271750 EC50 75.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccccc1Cl)N2 CHEMBL5404112 EC50 76.0 nM
Cc1ccccc1C(=O)N1CCN(c2nc(N3CCCC3)nc3ccccc23)CC1 CHEMBL5280450 EC50 79.0 nM
CCCCCCCCCCCCCCn1cc(CN[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)nn1 CHEMBL1086532 Ki 80.0 nM
CCCCCCCCCN[C@@H]1[C@H](N)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL3216774 IC50 81.0 nM
[N-]=[N+]=NC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O[C@H]12 CHEMBL3692693 Ki 83.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccccc1Br)N2 CHEMBL5396013 EC50 86.0 nM
CCCCCCCCCCn1cc(CN[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)nn1 CHEMBL1082596 Ki 90.0 nM
O=C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NCCCCNC(=S)N1[C@@H]2CO[C@H]1[C@H](O)[C@@H](O)[C@@H]2O CHEMBL4100971 Ki 90.0 nM
Cc1cc(N2CCN(C(=O)c3cc(-c4ccccc4)nc4c3cnn4C(C)C)CC2)nc(C(C)C)n1 CHEMBL4561657 EC50 90.0 nM
c1ccc(CCNc2nc(-c3cccnc3)nc3ccccc23)cc1 CHEMBL1193417 IC50 97.0 nM
O=S(=O)(NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O)c1cccc2ccccc12 CHEMBL3350089 Ki 100.0 nM
CCCCCCCCCCCC(=O)NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O CHEMBL3350087 Ki 100.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL574645 IC50 100.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(C(F)(F)F)c1 CHEMBL3354627 IC50 100.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nc(N2CCCC2)n1 CHEMBL5287675 EC50 100.0 nM
Cc1ccc(S(=O)(=O)Nc2ccc(C(=O)Nc3cc(C)on3)cc2)cc1 CHEMBL260582 Ki 102.0 nM
CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL408500 IC50 103.0 nM
OC[C@@H]1CNC[C@@H](O)[C@@H]1O CHEMBL1818432 Ki 110.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1cccc(F)c1Cl)N2 CHEMBL5425701 EC50 110.0 nM
Cc1cc(N2CCC(C)CC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 CHEMBL406704 Ki 120.0 nM
CCCCCCCCCO[C@H]1[C@@H](N)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL2164232 IC50 120.0 nM
Cc1ccccc1C(=O)N1CCN(c2nc(N3CCCC3)ncc2C)CC1 CHEMBL5289154 EC50 120.0 nM
Cc1cc(N2CCOCC2)nc2ccc(NC(=O)C3CC3)cc12 CHEMBL260291 Ki 121.0 nM
Cc1ccncc1-c1nc(NC2Cc3ccccc3C2)c2ccccc2n1 CHEMBL3906252 IC50 122.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CC(F)(F)CCCOCc1ccc(-c2ccccc2)cc1 CHEMBL3354620 IC50 125.0 nM
CCC1CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 CHEMBL3929224 IC50 126.0 nM
Cc1cccc(C(=O)N2CCN(c3cc(C)nc(N4CCCC4)n3)CC2)c1 CHEMBL5288960 EC50 130.0 nM
CCCCCCCCCCCCNC(=O)O/N=C1\N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CHEMBL3786086 Ki 140.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1cccc(Cl)c1Cl)N2 CHEMBL5401622 EC50 140.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1433409 Potency 141.3 nM
O=C(CCc1ccccc1)NC[C@@H]1N[C@H](CO)[C@H](O)[C@@H]1O CHEMBL3350088 Ki 150.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C)CC2)nc(C(C)C)n1 CHEMBL5265984 EC50 150.0 nM
CC(C)(C)c1ccc(C(=O)N2CCN(c3nc(N4CCCC4)nc4c3COC4)CC2)cc1 CHEMBL5282146 EC50 150.0 nM
Cc1cccc([C@H]2Nc3[nH]nc(C)c3[C@@H](O)[C@@H]2n2nnc3ccccc32)c1Cl CHEMBL5410576 EC50 150.0 nM
c1ccc2c(c1)CC(Nc1nc(-c3ccncc3)nc3ccccc13)C2 CHEMBL3957610 IC50 168.0 nM
CCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OCCCCCCCCC CHEMBL2164229 IC50 170.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C)CC2)nc(N2CCCCC2)n1 CHEMBL5278339 EC50 170.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3F)CC2)nc(N2CCCC2)n1 CHEMBL5287219 EC50 170.0 nM
c1cncc(-c2nc(NC3CCCCC3)c3ccccc3n2)c1 CHEMBL3920301 IC50 177.0 nM
CCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029770 Ki 180.0 nM
Cc1cc(N2CCCCC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 CHEMBL260290 Ki 184.0 nM
O=S(=O)(c1ccc(F)cc1)N1CCN(c2nc(-c3cccs3)nc3cc(Cl)ccc23)CC1 CHEMBL1434731 Potency 199.5 nM
OC[C@H]1N[C@H](CO)[C@@H](O)[C@H]1O CHEMBL469844 Ki 200.0 nM
OC1C(O)C2N=C(Nc3ccccc3)OC2C1O CHEMBL86865 IC50 200.0 nM
CCCCCCCCCn1cc(CN[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)nn1 CHEMBL1085393 IC50 200.0 nM
CCCC(=O)NCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029781 Ki 200.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL3354016 IC50 200.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(F)c1 CHEMBL3354625 IC50 200.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1C(F)(F)F CHEMBL3354626 IC50 200.0 nM
OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL1088158 IC50 200.0 nM
Cc1ccccc1C(=O)N1CCN(c2cc(CO)nc(N3CCCC3)n2)CC1 CHEMBL5289693 EC50 220.0 nM
COc1ccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)cc1OC CHEMBL1393956 Potency 223.9 nM
O=S(=O)(c1ccccc1C(F)(F)F)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1435323 Potency 223.9 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](C1CCCCCC1)N2 CHEMBL5404283 EC50 230.0 nM
FC1(F)CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 CHEMBL3980248 IC50 234.0 nM
CCN(CC)C(=O)CCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL2029784 Ki 250.0 nM
O=C(CCCN[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O)NC12CC3CC(CC(C3)C1)C2 CHEMBL3220377 Ki 250.0 nM
Cc1ccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)cc1 CHEMBL3354039 IC50 250.0 nM
Cc1cccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)c1 CHEMBL3354040 IC50 250.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2cccc(F)c2)cc1 CHEMBL3354049 IC50 250.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc3c(c2)OCCO3)cc1 CHEMBL3354055 IC50 250.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1F CHEMBL3354624 IC50 250.0 nM
O=C(NC(COCc1cn(CCOCCOc2ccc(-c3cn(C[C@H]4NC[C@@H](O)[C@H]4O)nn3)cc2)nn1)(COCc1cn(CCOCCOc2ccc(-c3cn(C[C@H]4NC[C@@H](O)[C@H]4O)nn3)cc2)nn1)COCc1cn(CCOCCOc2ccc(-c3cn(C[C@H]4NC[C@@H](O)[C@H]4O)nn3)cc2)nn1)c1cc(C(=O)NC(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)cc(C(=O)NC(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)c1 CHEMBL4792854 IC50 250.0 nM
Cc1ccccc1C(=O)N1CCN(c2nc(N3CCCC3)nc(C)c2C)CC1 CHEMBL5290054 EC50 250.0 nM
COC1CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 CHEMBL3965871 IC50 251.0 nM
O=S(=O)(c1ccc2ccccc2c1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1361379 Potency 251.2 nM
Cc1ccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)cc1 CHEMBL1357878 Potency 259.0 nM
O=S(=O)(c1ccccc1Cl)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1354978 Potency 259.0 nM
O=S(=O)(c1ccc2c(c1)CCCC2)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1314035 Potency 281.8 nM
c1cncc(-c2nc(NC3CC4CCC3C4)c3ccccc3n2)c1 CHEMBL3970989 IC50 282.0 nM
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](NCc2cn(CCCCC3CCCCC3)nn2)[C@H](O)[C@H]1O CHEMBL1766474 Ki 290.0 nM
O=S(=O)(c1ccc2c(c1)OCO2)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1472565 Potency 290.6 nM
Cc1ccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)c(C)c1 CHEMBL1434754 Potency 290.6 nM
CCCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O CHEMBL1083795 Ki 300.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccccc1 CHEMBL3354021 IC50 300.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1cccc(-c2ccccc2)c1 CHEMBL3354063 IC50 300.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCC(F)(F)COCc1ccc(-c2ccccc2)cc1 CHEMBL3354621 IC50 300.0 nM
C[C@@H](OCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccc(-c2ccccc2)cc1 CHEMBL3354623 IC50 300.0 nM
O=C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NCCCCNC(=S)N1[C@@H]2CO[C@H]1[C@H](O)[C@@H](O)[C@@H]2O CHEMBL4077472 Ki 300.0 nM
O=S(=O)(c1ccccc1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1336452 Potency 316.2 nM
S=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 CHEMBL103769 Potency 316.23 nM
COc1ccc(Cl)cc1Nc1nc(NCCO)nc(N2CCCC2)n1 CHEMBL429079 Ki 320.0 nM
CC(C)(C)Oc1ccccc1Nc1nc(NCCO)nc(N2CCCC2)n1 CHEMBL236925 IC50 330.0 nM
C#CCOc1ccc(C(=O)c2ccc(C(=O)NCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)cc1 CHEMBL590070 IC50 350.0 nM
N#Cc1ccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)cc1 CHEMBL3354045 IC50 350.0 nM
COc1ccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)cc1 CHEMBL1551656 Potency 354.8 nM
O=S(=O)(c1ccc(Cl)cc1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1348672 Potency 354.8 nM
Cc1cc(N2CCN(C(=O)C3CCCCC3)CC2)nc(N2CCCC2)n1 CHEMBL5287823 EC50 360.0 nM
O=S(=O)(c1ccc2ncsc2c1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1354192 Potency 365.9 nM
CCOC(=O)c1ccccc1S(=O)(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1395506 Potency 365.9 nM
OCCNc1nc(Nc2cc(-c3ccccc3)ccc2O)nc(N2CCCC2)n1 CHEMBL427852 IC50 370.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](C1CCCCC1)N2 CHEMBL5408859 EC50 370.0 nM
Cc1cc(C)cc(N(CC(=O)NC2CCC(C)CC2)S(=O)(=O)c2c(C)nc(O)nc2O)c1 CHEMBL1354148 Potency 398.1 nM
Cc1cc(C)cc(N(CC(=O)NC2CCCCCC2)S(=O)(=O)c2c(C)nc(O)nc2O)c1 CHEMBL1441203 Potency 398.1 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@]2(O)CC[C@H]1N2 CHEMBL1682493 IC50 400.0 nM
O=C(CC(c1ccccc1)(c1ccccc1)c1ccccc1)NCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL2414882 Ki 400.0 nM
O=C(CC1c2ccccc2-c2ccccc21)NCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL2414880 Ki 400.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC1C2CC3CC(C2)CC1C3 CHEMBL3354019 IC50 400.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1 CHEMBL3354025 IC50 400.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(F)cc2)cc1 CHEMBL3354048 IC50 400.0 nM
c1cncc(-c2nc(NCC3CCCCC3)c3ccccc3n2)c1 CHEMBL3963682 IC50 405.0 nM
Cc1ccccc1C(=O)N1CCN(c2nc(N3CCCC3)nc3c2COCC3)CC1 CHEMBL5285193 EC50 410.0 nM
CN(c1nc(-c2cccnc2)nc2ccccc12)[C@H]1CCc2ccccc2C1 CHEMBL4448041 IC50 430.0 nM
CC1(C)CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 CHEMBL3894465 IC50 431.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)CCN1CC1CCNCC1 CHEMBL3669171 Ki 440.0 nM
OC[C@H]1CN(CC2CCNCC2)C[C@@H](O)[C@@H]1O CHEMBL3926875 Ki 440.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C)CC2)nc(N2CCC2)n1 CHEMBL5271587 EC50 440.0 nM
O=C(CCCSCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O)N1CCOCC1 CHEMBL2029785 Ki 450.0 nM
Cc1cc(N2CCN(C(=O)Cc3ccccc3)CC2)nc(N2CCCC2)n1 CHEMBL5272952 EC50 460.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccccc1C(F)(F)F)N2 CHEMBL5395260 EC50 470.0 nM
CCc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccccc1Cl)N2 CHEMBL5436521 EC50 480.0 nM
CN(C)c1cccc2c(S(=O)(=O)NCCO)cccc12 CHEMBL27943 Ki 500.0 nM
CCCCCCCCCOCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL1651633 IC50 500.0 nM
CCCCCCCCOCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO CHEMBL1651632 IC50 500.0 nM
O=C(CCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)NC12CC3CC(CC(C3)C1)C2 CHEMBL2170199 IC50 500.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCC/C=C\C12CC3CC(CC(C3)C1)C2 CHEMBL3354015 IC50 500.0 nM
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCN5C[C@H](O)[C@@H](O)[C@H](O)[C@H]5CO)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3354018 IC50 500.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccc3cccc4ccc1c2c34 CHEMBL3354024 IC50 500.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL3354051 IC50 500.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc3c(c2)OCO3)cc1 CHEMBL3354054 IC50 500.0 nM
CCOC(=O)c1ccc(S(=O)(=O)N2CCN(c3nc(-c4ccccc4)nc4ccccc34)CC2)cc1 CHEMBL1396821 Potency 501.2 nM
O=S(=O)(c1ccccc1F)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1393971 Potency 501.2 nM
CCN(CC)c1cc(C)c2cc(NC(=O)C3CCC(C)CC3)ccc2n1 CHEMBL258515 Ki 514.0 nM
CCCCCCCCCN(CCCCCCCCC)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL2164233 IC50 530.0 nM
Cc1ccccc1C(=O)N1CCN(c2nc(N3CCCC3)nc3c2COC3)CC1 CHEMBL5267578 EC50 540.0 nM
O=C(NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O)c1cccc2ccccc12 CHEMBL3350093 Ki 550.0 nM
O=C(Nc1cccs1)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL264147 Ki 556.0 nM
CCC[C@H]1NC[C@@H](O)[C@H](O)[C@H]1O CHEMBL1089185 IC50 560.0 nM
O=S(=O)(c1ccccc1Br)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1314058 Potency 562.3 nM
O=[N+]([O-])c1ccccc1S(=O)(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1476627 Potency 562.3 nM
O[C@@H]1c2ccncc2N[C@H](c2ccccc2Cl)[C@H]1n1nnc2ccccc21 CHEMBL5440207 EC50 570.0 nM
CN1CCOc2cc(S(=O)(=O)N3CCN(c4nc(-c5cccs5)nc5ccccc45)CC3)ccc21 CHEMBL1550887 Potency 579.9 nM
O=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 CHEMBL1474351 IC50 600.0 nM
COc1ccccc1-c1ccc(COCCCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)cc1 CHEMBL3354044 IC50 600.0 nM
N#Cc1ccccc1-c1ccc(COCCCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)cc1 CHEMBL3354047 IC50 600.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2F)cc1 CHEMBL3354050 IC50 600.0 nM
O=C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NCCCCCCCCCNC(=S)N1[C@@H]2CO[C@H]1[C@H](O)[C@@H](O)[C@@H]2O CHEMBL4093241 Ki 600.0 nM
Cc1cc(N2CCN(C(=O)c3ccccc3C)CC2)nc(N(C)C)n1 CHEMBL5272591 EC50 630.0 nM
S=C(NCCCCN(Cc1ccc(Cl)cc1)c1ccc(Br)cn1)NCCCc1cnc[nH]1 CHEMBL1433325 Potency 635.2 nM
O=C(Nc1cccs1)O/N=C1\N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CHEMBL3787337 Ki 640.0 nM
Cc1cccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)n1 CHEMBL1400476 Potency 650.6 nM
Cc1cc(N2CC3CN(C(=O)c4ccccc4C)CC3C2)nc(N2CCCC2)n1 CHEMBL5283330 EC50 660.0 nM
CCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC CHEMBL2164228 IC50 670.0 nM
Cc1ccccc1C(=O)N1CCN(c2ccnc(N3CCCC3)n2)CC1 CHEMBL5270914 EC50 680.0 nM
CCCCCCCCCN1C(=O)N(CCCCCCCCC)[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]21 CHEMBL2012656 Ki 700.0 nM
N#Cc1cccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)c1 CHEMBL3354046 IC50 700.0 nM
CCCCC(C(=O)c1ccc(OCCN(C)C)cc1)c1ccccc1C(C)C CHEMBL4649463 EC50 700.0 nM
CC(C)(C)C(=O)OCCNc1nc(-c2ccccc2)nc2ccccc12 CHEMBL1415959 Potency 707.9 nM
O=S(=O)(c1ccc(F)cc1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1315035 Potency 712.7 nM
c1cncc(-c2nc(NC3CCCC3)c3ccccc3n2)c1 CHEMBL3968279 IC50 720.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1cc(Cl)ccc1Cl)N2 CHEMBL5422651 EC50 720.0 nM
OCCNc1nc(Nc2cc(Cl)ccc2O)nc(N2CCCC2)n1 CHEMBL237350 IC50 730.0 nM
COc1ccccc1S(=O)(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1398519 Potency 730.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccc(Cl)cc1Cl)N2 CHEMBL5413426 EC50 740.0 nM
CCOc1ccccc1Nc1nc(NCCO)nc(N2CCCC2)n1 CHEMBL441134 IC50 770.0 nM
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](NCc2cn(CCC(c3ccccc3)c3ccccc3)nn2)[C@H](O)[C@H]1O CHEMBL1766470 Ki 770.0 nM
CCCCCCCCCCCCC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O CHEMBL5172851 IC50 770.0 nM
CCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O CHEMBL2163840 IC50 780.0 nM
CCCCCCCCCN[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O CHEMBL2219956 IC50 780.0 nM
O=S(=O)(c1cccc(C(F)(F)F)c1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1472511 Potency 794.3 nM
O=S(=O)(c1ccc(Br)cc1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1354095 Potency 794.3 nM
N#Cc1ccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)cc1 CHEMBL1474062 Potency 794.3 nM
CCOC(=O)c1ccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)cc1 CHEMBL1550940 Potency 794.3 nM
O=S(=O)(c1ccc2ncccc2c1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1436663 Potency 799.7 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL3354052 IC50 800.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1 CHEMBL3354053 IC50 800.0 nM
O=S(=O)(c1cccc2ccccc12)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1472535 Potency 819.1 nM
O=S(=O)(c1cccs1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1314131 Potency 819.1 nM
COc1cccc(S(=O)(=O)N2CCN(c3nc(-c4cccs4)nc4ccccc34)CC2)c1 CHEMBL1550906 Potency 819.1 nM
OC[C@H]1N[C@H](CCCCCCCC2CCc3ccccc3C2)[C@@H](O)[C@@H]1O CHEMBL5190439 IC50 820.0 nM
c1cncc(-c2nc(NC3CCc4ccccc43)c3ccccc3n2)c1 CHEMBL3970658 IC50 821.0 nM
c1cncc(-c2nc(NCCC3CCCCC3)c3ccccc3n2)c1 CHEMBL3898722 IC50 857.0 nM
c1cncc(-c2nc(NC3CCCc4ccccc43)c3ccccc3n2)c1 CHEMBL3932095 IC50 872.0 nM
CC(C)CCCN1CC[C@@H](O)[C@H](O)[C@H]1CO CHEMBL3669176 Ki 880.0 nM
CC(C)CCCN1C[C@H](CO)[C@@H](O)[C@H](O)C1 CHEMBL3912485 Ki 880.0 nM
OCCCCCCCCCCn1cc(CN[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)nn1 CHEMBL1766489 Ki 890.0 nM
CN(CCOc1ccccc1)c1nc(-c2cncnc2)nc2ccccc12 CHEMBL4557217 AC50 890.0 nM
c1cncc(-c2nc(NC3CCCOC3)c3ccccc3n2)c1 CHEMBL3921895 IC50 891.0 nM
O=S(=O)(c1cnc2ccccc2c1)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1 CHEMBL1589703 Potency 897.2 nM
OC1CCN2C[C@H](O)[C@@H](O)[C@H](O)C12 CHEMBL421040 Ki 900.0 nM
O=C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NCCCCCCCCCNC(=S)N1[C@@H]2CO[C@H]1[C@H](O)[C@@H](O)[C@@H]2O CHEMBL4076141 Ki 900.0 nM
c1cncc(-c2nc(NC34CC5CC(CC(C5)C3)C4)c3ccccc3n2)c1 CHEMBL3908863 IC50 926.0 nM
CCOc1ccc(Cl)cc1Nc1nc(NCCO)nc(N2CCCC2)n1 CHEMBL237560 IC50 960.0 nM
Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccccc1F)N2 CHEMBL5440774 EC50 970.0 nM
Cc1cc(N2CCN(c3ncccn3)CC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 CHEMBL259330 Ki 975.0 nM