CC1(C)CC(C(Nc2cnc(-n3cc(C(F)(F)F)cn3)nc2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3617567 Ki 5.55 nM
Cc1cc(OC(c2ccc(C(=O)NCCC(=O)O)cc2)C2CCC2)cc(C)c1-n1cc(C(F)(F)F)cn1 CHEMBL3648156 Ki 5.75 nM
CC1(C)CC(C(Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3648139 Ki 7.6 nM
O=C(O)CCNC(=O)c1ccc([C@@H](Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)C2CCCCC2)cc1 CHEMBL3648191 Ki 9.05 nM
Cc1cc2cc(F)ccc2nc1NC(c1ccc(C(=O)NCCC(=O)O)cc1)C1CC(C)(C)C1 CHEMBL3617569 Ki 14.0 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)C2CCCCC2)cc1 CHEMBL3648133 Ki 17.0 nM
CCC[C@H](Nc1ccc(-n2cc(C(C)(C)C)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648188 Ki 20.2 nM
CC1(C)CC(C(Nc2cnc3cc(F)ccc3c2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3681967 Ki 25.0 nM
CCCC(Nc1ccc(-n2cc(-c3ccccc3)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648167 Ki 25.7 nM
O=C(O)CCNC(=O)c1ccc([C@H](Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)C2CCCCC2)cc1 CHEMBL3648192 Ki 26.7 nM
Cc1cc([C@@H](CC(C)C)Nc2ccc(C(=O)NCCC(=O)O)cn2)cc(C)c1-n1cc(C(F)(F)F)cn1 CHEMBL3648171 Ki 27.4 nM
Cc1cc(C(Nc2ccc(C(=O)NCCC(=O)O)cn2)C2CCCC2)cc(C)c1-n1cc(C(F)(F)F)cn1 CHEMBL3648173 Ki 28.0 nM
CCCC(Nc1ccc(-n2cnc(-c3ccccc3)c2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648151 Ki 29.3 nM
CCC[C@@H](Nc1ccc(-n2cc(C(C)(C)C)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648187 Ki 30.2 nM
CCCC(Oc1cc(C)c(-n2cc(C(F)(F)F)cn2)c(OC)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648164 Ki 32.3 nM
O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3Cl)cc2)cc1 CHEMBL3617574 Ki 33.0 nM
CC1(C)CC([C@H](Nc2ccc(-n3cnc(C(F)(F)F)c3)nc2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3648186 Ki 35.0 nM
Cc1cc(OC(c2ccc(C(=O)NCCC(=O)O)cc2)C2CC(C)(C)C2)cc(C)c1-n1cc(C(F)(F)F)cn1 CHEMBL3648163 Ki 35.2 nM
O=C(O)CCNC(=O)c1ccc(-c2ccccc2CNc2ccc(-c3ccc(F)c([N+](=O)[O-])c3)cc2)cc1 CHEMBL3673117 Ki 38.0 nM
CCCC(Nc1cnc(-n2cc(C(F)(F)F)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL2381823 Ki 38.2 nM
CCOC(=O)CCNC(=O)c1ccc(C(Nc2cnc(-n3cc(C(F)(F)F)cn3)nc2)C2CC(C)(C)C2)cc1 CHEMBL3648195 Ki 41.0 nM
CC1(C)CC(C(Nc2ccc(-n3cnc(C(F)(F)F)c3)nc2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3648181 Ki 42.2 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2cnc(-n3cnc(C(F)(F)F)c3)nc2)C2CCCC2)cc1 CHEMBL3648183 Ki 44.7 nM
Cc1cc(C(=O)NCCC(=O)O)ccc1-c1ccccc1CNc1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL3673116 Ki 45.0 nM
CC(C)(C)c1cn(-c2ccc(NC(c3ccc(C(=O)NCCC(=O)O)cc3)C3CCCC3)cn2)cn1 CHEMBL3648145 Ki 45.7 nM
CCC[C@H](Oc1cc(C)c(-n2cc3ccccc3n2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648184 Ki 47.8 nM
CC1(C)CC(C(Nc2cnc3ccc(F)cc3c2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3681968 Ki 50.0 nM
Cc1cc(OC(c2ccc(C(=O)NCCC(=O)O)cc2)C2CCCC2)cc(C)c1-n1cnc(C(F)(F)F)c1 CHEMBL3648153 Ki 51.0 nM
Cc1cc2ccccc2nc1NC(c1ccc(C(=O)NCCC(=O)O)cc1)C1CC(C)(C)C1 CHEMBL3617568 Ki 53.0 nM
CCCC(Nc1ccc(-n2cc(C(F)(F)F)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1F CHEMBL3648137 Ki 57.2 nM
CC(C)C[C@H](Nc1ccc(-n2cc(C(F)(F)F)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cn1 CHEMBL3648190 Ki 57.4 nM
CCCC(Oc1ccc(-n2cc(-c3ccccc3)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648155 Ki 58.0 nM
O=C(O)CCNC(=O)c1ccc(-c2ccccc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cc1 CHEMBL3673123 Ki 60.0 nM
CCCC(Oc1cc(C)c(-n2cc(C3CC3)cn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648160 Ki 62.6 nM
CCCC(Oc1ccc(-n2cc3cc(Cl)ccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648158 Ki 62.8 nM
Cc1nn(-c2ccc(NC(c3ccc(C(=O)NCCC(=O)O)cc3)C3CCCC3)cn2)cc1Cl CHEMBL3648168 Ki 65.9 nM
Cc1cc(NC(CC(C)C)c2ccc(C(=O)NCCC(=O)O)cc2)cnc1-n1cc(C(F)(F)F)cn1 CHEMBL3648134 Ki 69.8 nM
O=C(O)CCNC(=O)c1ccc(C(CC2CC2)Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)cc1 CHEMBL3648136 Ki 71.6 nM
Cc1cc2ccccc2nc1NC(CC(C)C)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681959 Ki 76.0 nM
CC(C)(C)C(Nc1ccc(-n2cnc(C(F)(F)F)c2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648176 Ki 87.2 nM
CC(C)c1cn(-c2ccc(NC(c3ccc(C(=O)NCCC(=O)O)cc3)C3CCCC3)cn2)cn1 CHEMBL3648146 Ki 88.4 nM
CCCC(Oc1cc(C)c(-n2cnc(C(F)(F)F)c2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648159 Ki 89.5 nM
CC(C)CC(Nc1ccc2cc(C(F)(F)F)ccc2n1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681963 Ki 91.0 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)C2CCC2)cc1 CHEMBL3648135 Ki 91.9 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cnc(C(F)(F)F)c3)nc2)C2CCCC2)cc1 CHEMBL3648132 Ki 93.0 nM
CCCC(Oc1cc(C)c(-n2cc(Cl)cn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648152 Ki 93.2 nM
CC1(C)CC(C(Oc2cnc(-n3cc(C(F)(F)F)cn3)nc2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3648193 Ki 94.9 nM
CCCC(Oc1ccc(-n2cc3cccc(C)c3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648147 Ki 98.2 nM
CCCC(Nc1ccc(-n2cc(C3CC3)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648174 Ki 101.0 nM
O=C(O)CCNC(=O)c1ccc(C(Oc2ccc(-n3cc4ccccc4n3)cc2)C2CCCC2)cc1 CHEMBL3648142 Ki 103.0 nM
CCCC(Oc1ccc(-n2cc3ccccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL2381825 Ki 109.0 nM
CCCC(Oc1cc(C)c(-n2cc3ccccc3n2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648180 Ki 109.0 nM
Cc1c(NC(CC(C)C)c2ccc(C(=O)NCCC(=O)O)cc2)cnc2ccccc12 CHEMBL3681965 Ki 109.0 nM
CC1(C)CC([C@@H](Nc2ccc(-n3cnc(C(F)(F)F)c3)nc2)c2ccc(C(=O)NCCC(=O)O)cc2)C1 CHEMBL3648185 Ki 110.0 nM
O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cc1F CHEMBL3673118 Ki 120.0 nM
CCCC(Oc1cc(C)c(-n2cc(C(F)(F)F)nn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648161 Ki 125.0 nM
CCCC(Nc1ccc(-n2cc(-c3ccccc3)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cn1 CHEMBL3648154 Ki 132.0 nM
Cc1cc2ccc(F)cc2nc1NC(c1ccc(C(=O)NCCC(=O)O)cc1)C1CC(C)(C)C1 CHEMBL3681966 Ki 133.0 nM
CCCC(Oc1ccc(-n2cc3cc(F)ccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648178 Ki 137.0 nM
CCCC(Nc1ccc(-n2cc(-c3ccccc3)cn2)nc1)c1ccc(C(=O)N(C)CCC(=O)O)cc1 CHEMBL3648170 Ki 142.0 nM
CCCC(Nc1ccc(-n2cc(C(F)(F)F)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1C CHEMBL3648138 Ki 143.0 nM
Cc1ccc2ncc(NC(CC(C)C)c3ccc(C(=O)NCCC(=O)O)cc3)cc2c1 CHEMBL3681969 Ki 160.0 nM
CCCC(Oc1ccc(-n2cc3ccc(C)cc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648148 Ki 161.0 nM
CCC[C@@H](Nc1nc2ccccc2cc1C)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681950 Ki 173.0 nM
CCCC(Oc1ccc(-n2cc3ccc(F)cc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648179 Ki 175.0 nM
Cc1cc(-n2cc(C(F)(F)F)cn2)ccc1C(Nc1ccc(C(=O)NCCC(=O)O)cn1)C1CCCCC1 CHEMBL3648141 Ki 183.0 nM
CCCC(Nc1ccc(-n2cc(-c3ccccn3)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648169 Ki 192.0 nM
Cc1cc([C@H](CC(C)C)Nc2ccc(C(=O)NCCC(=O)O)cn2)cc(C)c1-n1cc(C(F)(F)F)cn1 CHEMBL3648172 Ki 193.0 nM
Cc1cc(NC(CC(C)C)c2ccc(C(=O)NCCC(=O)O)cc2)nc2ccccc12 CHEMBL3681958 Ki 198.0 nM
CC(C)CC(Nc1ccc2cccc(Cl)c2n1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681961 Ki 199.0 nM
CCCC(Oc1ccc(-n2cc(C(F)(F)F)cn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL2381850 Ki 203.0 nM
CCCC(Oc1ccc(-n2cc3cc(C)ccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648150 Ki 208.0 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cnc(Cl)c3)nc2)C2CCCC2)cc1 CHEMBL3648143 Ki 225.0 nM
CCCC(Oc1ccc(-n2cc(C(F)(F)F)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL2381829 Ki 233.0 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cnc(C(F)(F)F)c3)nc2)C2CC(F)(F)C2)cc1 CHEMBL3648165 Ki 235.0 nM
CCCC(Oc1cc(F)c(-n2cc(C(F)(F)F)cn2)c(F)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648177 Ki 240.0 nM
CC(C)CC(Nc1cnc2ccccc2c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681952 Ki 240.0 nM
O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(F)cc3)cc2)cc1F CHEMBL3673119 Ki 240.0 nM
O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3Cl)cc2)cc1F CHEMBL3673120 Ki 240.0 nM
Cc1cc(NC(CC(C)C)c2ccc(C(=O)NCCC(=O)O)cc2)nc2cc(F)ccc12 CHEMBL3681960 Ki 242.0 nM
CCOC(=O)CCNC(=O)c1ccc(C(Oc2cnc(-n3cc(C(F)(F)F)cn3)nc2)C2CC(C)(C)C2)cc1 CHEMBL3648194 Ki 251.0 nM
CCCC(Oc1ccc(-c2ccc(CC(C)C)cc2)nc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3645574 Ki 254.0 nM
Cc1ccc(-c2ccc(SC(CC(C)C)c3ccc(C(=O)NCCC(=O)O)cc3)cc2)cc1C CHEMBL3645573 Ki 265.0 nM
CC(Nc1ccc(-c2ccc(Cl)cc2)cc1)c1ccc(Cl)cc1-c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3673121 Ki 270.0 nM
CCC[C@H](Nc1nc2ccccc2cc1C)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681951 Ki 280.0 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cnc(C(F)(F)F)c3)nc2)C(F)(F)F)cc1 CHEMBL3648144 Ki 298.0 nM
CCCC(Oc1ccc(-n2cc(C(F)(F)F)cn2)cc1C)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648166 Ki 315.0 nM
CCCC(Oc1ccc(-n2cc3c(C)cccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648149 Ki 316.0 nM
CCCC(Oc1ccc(-n2cc3cccc(Cl)c3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648157 Ki 354.0 nM
Cc1nc2ccccc2cc1NC(CC(C)C)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681964 Ki 360.0 nM
CCCC(Nc1ccc(C(=O)NCCC(=O)O)cn1)c1ccc(-n2cc(C(F)(F)F)cn2)nc1 CHEMBL3648182 Ki 399.0 nM
O=C(O)CCNC(=O)c1ccc(C(Nc2ccc(-n3cc(C(F)(F)F)cn3)nc2)C2CCOCC2)cc1 CHEMBL3648175 Ki 432.0 nM
CCCC(Oc1cnc(-n2cc(C(F)(F)F)cn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648162 Ki 446.0 nM
CC(C)CC(Nc1ccc2ccccc2n1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681954 Ki 452.0 nM
CCCC(Oc1ccc(-n2cc3ccccc3n2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648140 Ki 464.0 nM
CC(C)CC(Nc1ccc2ccc(C(F)(F)F)cc2n1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681962 Ki 479.0 nM
CC(C)CC(Nc1cc2ccccc2cn1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681957 Ki 531.0 nM
CCCC(Oc1ccc(-c2cc(C(F)(F)F)nn2C)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648131 Ki 556.0 nM
CC(C)C[C@@H](Nc1ccc(-n2cc(C(F)(F)F)cn2)nc1)c1ccc(C(=O)NCCC(=O)O)cn1 CHEMBL3648189 Ki 636.0 nM
CCCC(Oc1ccc(-n2cc(Cl)c(C)n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3648129 Ki 665.0 nM
CC(Nc1ccc(-c2ccc(F)cc2)cc1)c1ccc(Cl)cc1-c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3673122 Ki 770.0 nM
O=C(O)CCNC(=O)c1ccc(C(CC(F)(F)F)Nc2cnc3ccccc3c2)cc1 CHEMBL3681970 Ki 930.0 nM
Cc1nc2ccccc2nc1NC(CC(C)C)c1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL3681956 Ki 979.0 nM