COc1cc(/C=N/Nc2ccc(Cl)nn2)cc(OC)c1O CHEMBL2001554 AC50 5.0 nM
Oc1ccc(/C=N/n2c(S)nnc2COc2ccccc2)cc1O CHEMBL3194699 AC50 5.0 nM
COc1ccc(CSC2=NCCN2)cc1Br CHEMBL1314092 AC50 7.0 nM
COc1ccc(-c2n[nH]c(S)n2)cc1 CHEMBL1334528 AC50 8.0 nM
CC[C@@H]1[C@H]2CCCC(=O)N3CC[C@@H](C[C@@H]1Nc1ccccc1)[C@@H]23 CHEMBL1590507 AC50 8.0 nM
COc1ccc(N/N=C(\C=N\O)C(=O)c2ccc(OC)cc2)cc1 CHEMBL1994372 AC50 9.0 nM
CCCN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3 CHEMBL538542 AC50 9.0 nM
O=C(O)c1ccc(N2C(=O)/C(=C/c3nc4ccccc4[nH]3)SC2=S)cc1 CHEMBL1451763 AC50 9.0 nM
COc1ccc(Cn2c(S)nnc2-c2ccc(OC)cc2)cc1 CHEMBL1321939 AC50 9.0 nM
COc1ccccc1C(=O)N1CCN=C1SCc1cccnc1 CHEMBL1383770 AC50 9.0 nM
O=C(NCCCN1CCCC1)c1ccc2c(Cl)c3c(nc2c1)CCCC3 CHEMBL1384636 AC50 10.0 nM
Sc1nnc(-c2ccc3ccccc3n2)o1 CHEMBL1421202 AC50 10.0 nM
O=C(NCc1cccs1)C(=O)NCC(c1ccco1)N1CCN(c2ccccc2)CC1 CHEMBL1345455 AC50 10.0 nM
O=C(O)c1cccc(NC(=O)c2cc(-c3cccc(Cl)c3)nc3ccccc23)c1 CHEMBL1393642 AC50 10.0 nM
CCN(CCNC(=O)C1CCCN(Cc2nc(-c3ccc(OC)cc3)oc2C)C1)c1ccccc1 CHEMBL1568298 AC50 10.0 nM
COc1ccc(-c2n[nH]c(S)n2)cc1OC CHEMBL1608601 AC50 11.0 nM
COc1cc(/C=N/n2c(S)nnc2-c2[nH]nc3c2CCC3)cc(OC)c1O CHEMBL3197392 AC50 11.0 nM
C/C(=N\Nc1ccc(C(=O)O)cc1)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL3197936 AC50 13.0 nM
CCN(CCNC(=O)C1CCN(S(=O)(=O)CC)CC1)c1ccccc1 CHEMBL1727288 AC50 13.0 nM
CC1(c2ccc(O)cc2)NC(=O)N(c2ccccc2)N1 CHEMBL1509716 AC50 15.0 nM
COc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 CHEMBL52101 AC50 16.0 nM
Cc1cccc(C(=O)Nc2scc(CC(C)C)c2C(=O)O)c1 CHEMBL1391665 AC50 16.0 nM
CN(C)S(=O)(=O)c1ccc(C(=O)N2CCN=C2SCc2cccnc2)cc1 CHEMBL1726783 AC50 17.0 nM
Cc1ccc2[nH]c(CCc3ccc(N)cc3)nc2c1 CHEMBL1461059 AC50 18.0 nM
COc1ccc(CSc2[nH]c(C)nc2[N+](=O)[O-])cc1[N+](=O)[O-] CHEMBL1353098 AC50 20.0 nM
C/C(=N\Nc1nc2ccccc2[nH]1)c1cccs1 CHEMBL3209857 AC50 20.0 nM
COc1ccc(CSC2=NCCN2)cc1Cl CHEMBL1580609 AC50 21.0 nM
O=C(NCCCN1CCCC1)c1ccc2c(c1)N(Cc1ccccc1)CCS2 CHEMBL1549086 AC50 22.0 nM
COc1ccccc1NS(=O)(=O)c1ccc(C)c(C(=O)N2CCN(c3ccc(O)cc3)CC2)c1 CHEMBL1730847 AC50 22.0 nM
CCN(CCNC(=O)C1CCN(Cc2nc(-c3cccc(Cl)c3)oc2C)CC1)c1ccccc1 CHEMBL1362247 AC50 24.0 nM
Cc1nc2c(C)cccc2cc1C(=O)N/N=C/c1ccc(O)cc1 CHEMBL2005764 AC50 25.0 nM
CC(=O)Nc1ccc(N2C(=O)CSC2c2ccccc2)cc1 CHEMBL1708249 AC50 25.0 nM
COc1cc(/C=N/Nc2nc3ccccc3o2)cc(OC)c1O CHEMBL3199692 AC50 25.0 nM
COc1cc(C)c(N)cc1C(C)C CHEMBL1376053 AC50 27.0 nM
Cc1nc(SCc2ccc(Cl)c(Cl)c2)ncc1C(=O)O CHEMBL1491555 AC50 27.0 nM
COc1cc(/C=N/NC2=NCCCCC2)ccc1O CHEMBL3208276 AC50 28.0 nM
CCCn1c2ccc(/C(C)=N\O)cc2c2cc(/C(C)=N/O)ccc21 CHEMBL3210311 AC50 28.0 nM
CC(=O)Nc1ccc(S(=O)(=O)NC(C)C(=O)NCCc2ccc(F)cc2)cc1 CHEMBL1411640 AC50 31.0 nM
CN1C(=O)C(=CNNc2ccccc2)C(=O)N(C)C1=O CHEMBL1093074 AC50 31.0 nM
O=C(C1CCCC1)N1CCN=C1SCc1cccc([N+](=O)[O-])c1 CHEMBL1462827 AC50 32.0 nM
O=c1oc2cc(Br)ccc2n1CSC1=NCCS1 CHEMBL1586957 AC50 33.0 nM
c1ccc2nc(N3CCCC3)c(N3CCCC3)nc2c1 CHEMBL1412545 AC50 34.0 nM
CCN(CC)C(=N)/C(C#N)=N/Nc1ccc(C)cc1 CHEMBL2369291 AC50 35.0 nM
COc1ccc2[nH]c3c(S)ncnc3c2c1 CHEMBL1409203 AC50 35.0 nM
COc1ccc(CNc2ncc(-c3cccc([N+](=O)[O-])c3)n2C)c(OC)c1OC CHEMBL1387497 AC50 35.0 nM
COc1ccc(-n2nnnc2S(=O)(=O)Cc2ccc(C(=O)O)cc2)cc1 CHEMBL1610977 AC50 38.0 nM
COc1cc(/C=N/NC(=O)c2cccc(S(=O)(=O)N3CCCC3)c2)cc(OC)c1O CHEMBL3196427 AC50 39.0 nM
COc1cc(C(=O)c2ccccc2)c(OC)cc1C(=O)Nc1ccc(O)cc1 CHEMBL1599886 AC50 39.0 nM
O=[N+]([O-])c1ccc(CSC2=NCCN2)cc1 CHEMBL1491577 AC50 40.0 nM
COc1cccc(OC)c1C(=O)N1CCN=C1SCc1cccnc1 CHEMBL1712248 AC50 43.0 nM
O=C(O)c1ccc(Sc2nnc(-c3cccc(Br)c3)o2)c([N+](=O)[O-])c1 CHEMBL1359763 AC50 44.0 nM
Sc1n[nH]c(-c2csc3c2CCCC3)n1 CHEMBL1407081 AC50 44.0 nM
Cc1ccc2nc(-c3cccc(S(=O)(=O)N(C)C)c3)cn2c1 CHEMBL1339120 AC50 45.0 nM
Cc1ccc(S(=O)(=O)N2CCN=C2SCc2cccnc2)cc1 CHEMBL1507790 AC50 46.0 nM
CNc1nnc(-c2cccc(N(C)C)c2)s1 CHEMBL1443752 AC50 46.0 nM
COc1ccc(C2SCC(=O)N2c2ccc(F)cc2)cc1 CHEMBL1721801 AC50 49.0 nM
O=C(NCc1cccnc1)c1ccc(COc2ccccc2Cl)cc1 CHEMBL1389995 AC50 55.0 nM
COc1ccccc1-c1nnc(S)n1-c1ccccc1 CHEMBL1510509 AC50 58.0 nM
COc1cc(-c2csc(CCn3nc(C)cc3C)n2)cc(OC)c1OC CHEMBL1469726 AC50 59.0 nM
O=C(NNc1c2ccccc2nc2ccccc12)c1ccc(O)cc1O CHEMBL1404929 AC50 62.0 nM
COc1ccc(C(=O)N2CCN=C2SCc2cccnc2)c(OC)c1 CHEMBL1332041 AC50 67.0 nM
O=S(=O)(c1ccc2ccccc2c1)N1CCN=C1SCc1cccnc1 CHEMBL1500343 AC50 72.0 nM
O=C(OCc1ccccc1)Oc1cncc(C(=O)O)c1 CHEMBL1409733 AC50 72.0 nM
CCSC1=NSC2=NC(=O)/C(=C\c3cccs3)C(=N)N12 CHEMBL1532785 AC50 75.0 nM
COc1ccccc1C(=O)Nc1ccc2c(c1)nc1n2CCSC1 CHEMBL1529007 AC50 76.0 nM
O=C(c1ccc2c(c1)OCO2)N1CCN=C1SCc1cccnc1 CHEMBL1336543 AC50 76.0 nM
COc1ccc(N/N=C(\C#N)C(=N)N2CCCCC2)cc1 CHEMBL2369243 AC50 77.0 nM
NNS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NN)ccc1-2 CHEMBL1477749 AC50 79.0 nM
O=C(NNc1c2ccccc2nc2ccccc12)c1ccccc1O CHEMBL1308971 AC50 80.0 nM
CC(=O)Nc1ccc(S(=O)(=O)NC(C)C(=O)NC(C)c2ccccc2)cc1 CHEMBL1415000 AC50 83.0 nM
O=C(O)C1CSC(c2coc3ccccc3c2=O)N1 CHEMBL1418892 AC50 83.0 nM
CN(CCCNC(=O)C1CCCN(S(=O)(=O)c2c[nH]cn2)C1)c1ccccc1 CHEMBL1470571 AC50 85.0 nM
COC(=O)c1sc(-c2ccc(C(C)(C)C)cc2)cc1NC(=O)c1ccccc1C(=O)O CHEMBL1596373 AC50 87.0 nM
Cc1cccc(C(=O)O/N=C2\C(=O)N(C)c3ccccc32)c1 CHEMBL3192061 AC50 88.0 nM
O=C(CN1C(=O)CCC1=O)NNc1ccc2ccccc2c1 CHEMBL1385093 AC50 90.0 nM
CC/C(C)=N/Nc1nc(-c2cc3cccc(OC)c3oc2=O)cs1 CHEMBL3193979 AC50 91.0 nM
COc1ccc(C2NC(=O)CS2)cc1OC CHEMBL1500593 AC50 93.0 nM
O=C(c1cc2ccccc2o1)N1CCN=C1SCc1cccnc1 CHEMBL1736762 AC50 95.0 nM
O=C(NNc1ccc(O)cc1)c1ccc(Br)cc1 CHEMBL1541889 AC50 96.0 nM
Sc1n[nH]c(-c2cccc(Cl)c2)n1 CHEMBL1352830 AC50 97.0 nM
Oc1ccc(-c2cn3ccccc3n2)cc1 CHEMBL1464022 AC50 97.0 nM
O=C(C1CCCCC1)N1CCN=C1SCc1cccnc1 CHEMBL1455000 AC50 97.0 nM
CCCCCC(=O)N/N=C/c1cc(Br)c(O)c(OC)c1 CHEMBL3207601 AC50 98.0 nM
Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)no1 CHEMBL1359781 AC50 98.0 nM
CN1CCCC(CN2c3ccccc3Sc3ccccc32)C1 CHEMBL1712842 AC50 98.0 nM
CC12CCC(C(=O)N/N=C/c3ccc(O)cc3)(OC1=O)C2(C)C CHEMBL3193304 AC50 99.0 nM
CC(=N\Nc1ccc(Cl)cc1)/C(=N/O)C(=O)Nc1ccccc1 CHEMBL3199548 AC50 104.0 nM
COc1cc(/C=N/NC(=O)c2cc(-c3c(C)nn(-c4ccccc4)c3C)[nH]n2)ccc1O CHEMBL1992164 AC50 105.0 nM
C/C(=N\NC(=O)c1ccc(N/N=C(\C)c2ccncc2)cc1)c1ccncc1 CHEMBL3211246 AC50 107.0 nM
CCCCN(CCCNc1[nH]cnc2ncnc1-2)c1ccccc1 CHEMBL1499041 AC50 108.0 nM
Cc1cc(NS(=O)(=O)c2ccc(Nc3nc(-c4ccc(O)cc4)cs3)cc2)no1 CHEMBL1577794 AC50 108.0 nM
O=C(O)CCn1cc(C=C2C(=O)NC(=O)NC2=O)c(-c2cc3ccccc3oc2=O)n1 CHEMBL1312932 AC50 109.0 nM
Cc1cc(-c2nnc(S)n2/N=C/C(Cl)=C/c2ccccc2)[nH]n1 CHEMBL1968326 AC50 109.0 nM
O=C1NN(c2ccccc2)C(=O)/C1=C/c1ccc(-c2ccc(C(=O)O)cc2)o1 CHEMBL1332506 AC50 110.0 nM
CC(=O)c1ccc(S(=O)(=O)NCC(=O)NC(c2nc3ccccc3[nH]2)C(C)C)cc1 CHEMBL1730480 AC50 113.0 nM
C/C(=N\Nc1nc2ccccc2[nH]1)c1ccc2c(c1)OCO2 CHEMBL3191810 AC50 116.0 nM
Cc1ccc(C(=O)NCCSc2snnc2C)cc1 CHEMBL1462337 AC50 117.0 nM
COC(=O)/C=C/S(=O)(=O)c1ccc(NC(C)=O)cc1 CHEMBL1353522 AC50 118.0 nM
CC(C)=NNc1nc(-c2ccc(N3C(=O)CCC3=O)cc2)cs1 CHEMBL1300856 AC50 119.0 nM
O=C1CC(N2CCN(c3ccc(O)cc3)CC2)C(=O)N1Cc1cccs1 CHEMBL1353353 AC50 123.0 nM
O=C(c1cccc(F)c1)N1CCN=C1SCc1cccnc1 CHEMBL1354038 AC50 123.0 nM
COc1ccc(N2C(=O)CSC2c2ccncc2)cc1 CHEMBL1735257 AC50 124.0 nM
Nc1c(-c2ccccc2)cnn1-c1cccc([N+](=O)[O-])c1 CHEMBL1326159 AC50 125.0 nM
O=C(N/N=C/c1ccc(O)c(O)c1)C1CC1 CHEMBL3195242 AC50 127.0 nM
Clc1ccc2[nH]c3c(c2c1)CCc1c[nH]nc1-3 CHEMBL1423096 AC50 129.0 nM
COc1cc(/C=N/NC(=O)c2cc(-c3ccco3)nc3ccccc23)cc(OC)c1O CHEMBL3199715 AC50 130.0 nM
CC(=O)Nc1ccc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccccc2)cc1 CHEMBL1580443 AC50 130.0 nM
CCCCN(CCCNC(=O)C1CCN(S(=O)(=O)CC)CC1)c1ccccc1 CHEMBL1310834 AC50 131.0 nM
Nn1c(S)nnc1Cc1ccccc1 CHEMBL1698033 AC50 134.0 nM
C/C(=N\Nc1ccc([N+](=O)[O-])cc1)c1ccc(O)cc1 CHEMBL324389 AC50 136.0 nM
CCCNC(=O)c1cc2c3ccccc3n(C)c2s1 CHEMBL1301245 AC50 137.0 nM
C/C(=N\Nc1ccc(Cl)c(C(=O)O)c1)c1cc2ccccc2o1 CHEMBL1986394 AC50 138.0 nM
C/C(=N\Nc1ccc([N+](=O)[O-])cc1)c1cccc(N)c1 CHEMBL1980031 AC50 140.0 nM
COc1cc(/C=C/c2cc(C(=O)O)c3ccccc3n2)cc(OC)c1O CHEMBL1310236 AC50 141.0 nM
COc1ccc(CNc2nc3ccccc3n2C(C)C)c(O)c1 CHEMBL1408233 AC50 146.0 nM
CCCC(=O)N1CCc2cc(-c3nc(N)sc3C)ccc21 CHEMBL1530938 AC50 149.0 nM
COc1cc(OC)cc(C(=O)N2CCN=C2SCc2cccnc2)c1 CHEMBL1328312 AC50 154.0 nM
Nc1ccc2oc(-c3cccs3)nc2c1 CHEMBL1346510 AC50 155.0 nM
CN(C)c1nc(Oc2ccc(/C=N/O)cc2)nc(N(C)C)n1 CHEMBL3213783 AC50 156.0 nM
Cc1cc(S(=O)(=O)N2CCN(c3ccccc3O)CC2)c(C)s1 CHEMBL1393567 AC50 156.0 nM
COc1cc(/C=C2/SC(=O)NC2=O)ccc1Oc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] CHEMBL1382299 AC50 156.0 nM
NC(=NO)c1ccc(NC(=O)c2ccc(Br)o2)cc1 CHEMBL1529010 AC50 160.0 nM
Cc1cccc(CS(=O)(=O)c2ncc(Cl)c(C(=O)Nc3c(C)cccc3C)n2)c1 CHEMBL1363679 AC50 164.0 nM
NC(=O)c1c(NC(=O)c2ccc(N3C(=O)CCC3=O)cc2)sc2c1CCCC2 CHEMBL1444580 AC50 165.0 nM
O=C1CCC(=O)N1CNc1ccc(Oc2ccccc2)cc1 CHEMBL1571944 AC50 166.0 nM
CC(=O)Nc1cccc(-c2csc(Nc3ccc(C)cn3)n2)c1 CHEMBL1598581 AC50 169.0 nM
CC(=O)Nc1nc(C)c(-c2csc(Nc3ccc(O)cc3)n2)s1 CHEMBL1455993 AC50 170.0 nM
CN(C)CCCSc1nc2ccccc2s1 CHEMBL1461615 AC50 171.0 nM
COc1cc(/C=N/NC(=O)CC(=O)NC2CCCCC2)ccc1O CHEMBL3213852 AC50 175.0 nM
Cc1nnc2sc(SCc3cccc(Cl)c3)nn2c1=O CHEMBL1567547 AC50 175.0 nM
O=C(O)c1cccc(S(=O)(=O)Nc2ccc(O)c(Sc3nc4ccccc4s3)c2)c1 CHEMBL1492448 AC50 176.0 nM
O=C1NC(=O)N(c2ccc(C(=O)O)cc2)C(=O)/C1=C/c1c[nH]c2ccccc12 CHEMBL1422585 AC50 177.0 nM
COc1cc(/C=N/NS(=O)(=O)c2ccc(C)c([N+](=O)[O-])c2)ccc1O CHEMBL3194974 AC50 181.0 nM
O=C(Nc1ccc(Cl)c(Cl)c1)Nc1ccccc1C(=O)O CHEMBL1489087 AC50 182.0 nM
Cc1nc(C)c(-c2csc(Nc3ccc(F)cc3)n2)s1 CHEMBL1472347 AC50 185.0 nM
Nc1nc(-c2ccc3ccccc3c2)cs1 CHEMBL1372017 AC50 188.0 nM
CN(C)c1ccc(C(=O)Nc2nc3c(s2)CCCC3)cc1 CHEMBL1450386 AC50 188.0 nM
CC(C)n1cc(/C=N/Nc2ccc(C(=O)O)cc2)c2ccccc21 CHEMBL3191946 AC50 192.0 nM
O=C(NNc1cc(Br)c(O)c(Br)c1)c1ccccc1 CHEMBL1458709 AC50 192.0 nM
Cc1ccc(N2C(=O)CSC2c2cccnc2)cc1F CHEMBL1389463 AC50 193.0 nM
c1ccc2[nH]c(SCc3cn4cccnc4n3)nc2c1 CHEMBL1424687 AC50 194.0 nM
Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 CHEMBL1382060 AC50 195.0 nM
Cc1cc(C)c(S(=O)(=O)Nc2ccc(N(C)C)cc2)c(C)c1-n1cnnn1 CHEMBL1503539 AC50 197.0 nM
CC(=O)N1CCN(c2ccc(NCc3ccc(F)cc3)cc2)CC1 CHEMBL1432345 AC50 198.0 nM
Cc1ccc(Oc2ccc(C(=N)NO)cc2)cc1C CHEMBL1330075 AC50 200.0 nM
COc1ccccc1NC(=O)c1cc(O)nc2ccccc12 CHEMBL1567500 AC50 202.0 nM
CN(C)c1ccc(NC(=O)Nc2ccc3snnc3c2)cc1 CHEMBL1330018 AC50 204.0 nM
C=C(c1ccc(O)cc1)c1ccc(O)cc1 CHEMBL1456900 AC50 205.0 nM
C/C(=N\NC(=O)c1cccc(N/N=C(\C)c2ccncc2)c1)c1ccncc1 CHEMBL3195202 AC50 205.0 nM
O=C(O)C(c1ccccc1)N1C(=O)/C(=C\c2ccc(O)c(O)c2)SC1=S CHEMBL1412423 AC50 208.0 nM
CCN(CC)S(=O)(=O)c1cccc(C(=O)N/N=C/c2cc(OC)c(O)c(OC)c2)c1 CHEMBL3195588 AC50 210.0 nM
Cc1cccc(Oc2ccc3c(c2)cc(C(=O)O)n3C)c1 CHEMBL1585213 AC50 211.0 nM
Cc1ccc(S(=O)(=O)NNC(=O)C(=O)NNc2ccccn2)cc1 CHEMBL1345687 AC50 213.0 nM
CCN(CC)c1ccc(NC(=O)c2cnn(CC)c2)cc1 CHEMBL1544764 AC50 215.0 nM
COC(=O)c1c(C(=O)OC)c(-c2ccc(F)cc2)n2c1CSC2 CHEMBL1317624 AC50 218.0 nM
O=C(O)c1ccccc1C(=O)Nc1ccc(-c2csc(-c3ccccc3)n2)cc1 CHEMBL1582181 AC50 218.0 nM
O=C(C[N+]1=C2SC=C(c3ccccc3)N2CC1)c1ccc(Br)cc1 CHEMBL1343516 AC50 221.0 nM
CCN(CC)CC(=O)Nc1ccc2c(c1)Nc1ccccc1CC2 CHEMBL1547549 AC50 221.0 nM
Cc1ccc(NNC(=O)c2ccno2)cc1Cl CHEMBL1463877 AC50 223.0 nM
O=C(CNCc1ccco1)Nc1ccc(N2CCCCCC2)cc1 CHEMBL1497149 AC50 224.0 nM
O=C1CSC(c2ccccn2)N1c1ccccc1 CHEMBL1700296 AC50 225.0 nM
COc1ccc(NC2CCCN(C(=O)c3csc(C(C)C)n3)C2)cc1 CHEMBL1499541 AC50 226.0 nM
Cc1ccc(-c2nc(-c3ccccn3)sc2CC(=O)O)cc1 CHEMBL1431998 AC50 226.0 nM
O=C1NN(c2ccccc2)C(=O)/C1=C/c1ccc(-c2cccc(C(=O)O)c2)o1 CHEMBL1359054 AC50 228.0 nM
Cc1ccc(N/N=C(\C#N)C(=N)N2CCCCC2)cc1 CHEMBL2369297 AC50 228.0 nM
COc1c(O)cc2oc(-c3ccc(O)c(O)c3)cc(=O)c2c1O CHEMBL172350 AC50 230.0 nM
Nc1cccc(-c2cn3cccnc3n2)c1 CHEMBL1528830 AC50 232.0 nM
Cc1ccc(-c2nc3ccccn3c2Nc2ccccc2)o1 CHEMBL1413585 AC50 235.0 nM
COc1cc(/C=N/NC(=O)CCn2nnc3ccccc32)ccc1O CHEMBL3209753 AC50 236.0 nM
O=C(O)c1ccc(S(=O)(=O)Nc2ccc(O)c(Sc3nc4ccccc4s3)c2)cc1 CHEMBL1391464 AC50 236.0 nM
O=C(CN1CCN(c2ccc(O)cc2)CC1)N(C1CC1)C1CCS(=O)(=O)C1 CHEMBL1708892 AC50 238.0 nM
CCc1ccc2cccc3c2c1N=CN3C CHEMBL1592490 AC50 240.0 nM
Nc1[nH]c(N=NC(=O)c2ccc(F)cc2)c2ccccc12 CHEMBL1313488 AC50 240.0 nM
COc1ccc(S(=O)(=O)N2CCN=C2SCc2cccnc2)cc1 CHEMBL1358996 AC50 243.0 nM
O=C(O)c1ccccc1NS(=O)(=O)c1cccc(-n2sc3ccccc3c2=O)c1 CHEMBL1333250 AC50 243.0 nM
O=C(CN1C(=O)NC2(CCCC2)C1=O)Nc1cc(Cl)ccc1N1CCCC1 CHEMBL1324456 AC50 244.0 nM
CC(C)C(=O)Nc1ccc2c(c1)nc1n2CCSC1 CHEMBL1359534 AC50 245.0 nM
Cc1ccc(Nc2ccc(C(=O)O)cc2N)cc1 CHEMBL1477639 AC50 246.0 nM
COc1ccc(C(=O)Oc2ccc(/C=N/O)cc2)cc1 CHEMBL3207730 AC50 247.0 nM
FC(F)(F)c1ccc(-c2n[nH]c(S)n2)cc1 CHEMBL1323804 AC50 248.0 nM
COc1cc(/C=N/NC2=NC(=O)C(c3ccccc3)S2)ccc1O CHEMBL3199415 AC50 249.0 nM
Cc1ccc(Sc2ccc(C=C3C(=O)N(C)C(=O)N(C)C3=O)o2)cc1 CHEMBL1492148 AC50 250.0 nM
CC(=O)Nc1ccc(SCCN2CC[C@@H](C(C)(C)C)CCC2=O)cc1 CHEMBL1354480 AC50 250.0 nM
CC(=O)Nc1ccc(S(=O)(=O)N2CCN=C2SCc2ccc([N+](=O)[O-])cc2)cc1 CHEMBL1542566 AC50 252.0 nM
Cc1csc(/C(=N/OC(=O)c2ccco2)C(N)=O)n1 CHEMBL3189366 AC50 252.0 nM
Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3cnc4n(c3=O)CCS4)cc2)c1C CHEMBL1448462 AC50 255.0 nM
O=C1NN(c2ccc(Cl)c(Cl)c2)C(=O)/C1=C/c1ccc(-c2ccccc2C(=O)O)o1 CHEMBL1433919 AC50 260.0 nM
O=C(O)c1cccc2c1-c1ccccc1/C2=N\Nc1ccccc1 CHEMBL3192368 AC50 264.0 nM
Cc1cccc(Sc2c([N+](=O)[O-])ncn2C)c1 CHEMBL1423986 AC50 265.0 nM
CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(Nc3ccccc3)cc2)cc1 CHEMBL1607166 AC50 268.0 nM
O=S(=O)(c1ccc(-c2csc(-c3cccnc3)n2)cc1)N1CCCC1 CHEMBL1500570 AC50 268.0 nM
Nc1cc([N+](=O)[O-])ccc1Nc1ccc(O)cc1 CHEMBL1608593 AC50 269.0 nM
Cc1ccc(Sc2c([N+](=O)[O-])ncn2C)cc1 CHEMBL1488395 AC50 270.0 nM
CC1(C)CC(Nc2ccc(Nc3ccccc3)cc2)CC(C)(C)N1 CHEMBL1367933 AC50 270.0 nM
COc1cc(/C=N/NC(=O)C2C3CCCCC32C)cc(Br)c1O CHEMBL3209332 AC50 272.0 nM
CC(=O)NC(C)C(c1cccs1)N1CCN(c2ccccc2)CC1 CHEMBL1440255 AC50 273.0 nM
Clc1ccccc1CSc1cn2c(n1)CCC2 CHEMBL1461809 AC50 273.0 nM
Cc1nc2cc(N)ccc2n1C1CCCCC1 CHEMBL1584895 AC50 277.0 nM
CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 CHEMBL1390362 AC50 278.0 nM
COc1ccc(/C=N/Nc2nc3ccccc3[nH]2)c(OC)c1OC CHEMBL3190073 AC50 278.0 nM
O=S1(=O)C=C(Sc2nnc(-c3ccccc3)o2)c2ccccc21 CHEMBL1602759 AC50 281.0 nM
COc1ccc(/C=N/Nc2nc3ccccc3[nH]2)cc1OC CHEMBL2037345 AC50 285.0 nM
Cc1cccc(-c2cnn(-c3cccc([N+](=O)[O-])c3)c2N)c1 CHEMBL1557147 AC50 287.0 nM
Cc1cc2oc3cc(NCCC4CCCN4C)ccc3c(=O)c2cc1C CHEMBL1306033 AC50 287.0 nM
CCN(CCNC(=O)C1CC(=O)N(CCc2ccccc2)C1)c1ccccc1 CHEMBL1384595 AC50 288.0 nM
Cc1ccc(Nc2nc(-c3ccc(O)cc3O)cs2)nc1 CHEMBL1400505 AC50 288.0 nM
Cc1ccc(/C=N\Nc2nc3cc(Cl)ccc3[nH]2)o1 CHEMBL3195732 AC50 289.0 nM
Nc1ccc(-c2nc3cc(N)ccc3o2)cc1 CHEMBL1380161 AC50 289.0 nM
CCN(CC)c1ccc(NC(=O)C2=CC=CN3CCS(=O)(=O)N=C23)cc1 CHEMBL1595897 AC50 295.0 nM
C/C(=N\Nc1nc2ccccc2[nH]1)c1ccc(C)o1 CHEMBL3197360 AC50 299.0 nM
CCC(C)C(=O)N1CCc2cc(-c3csc(N)n3)ccc21 CHEMBL1569243 AC50 300.0 nM
O=C(CN1CCN(c2ccccc2O)CC1)NCCCc1ccccc1 CHEMBL1350548 AC50 301.0 nM
Fc1ccc(-c2ccnc(S)n2)cc1 CHEMBL1498152 AC50 301.0 nM
Oc1cc2ccccc2cc1-c1nnc(S)o1 CHEMBL1599981 AC50 301.0 nM
C(=N/Nc1nc2ccccc2[nH]1)\c1c[nH]c2ccccc12 CHEMBL2002487 AC50 309.0 nM
Cc1cc(C)nc(Nc2n[nH]c(-c3ccc(N)cc3)n2)n1 CHEMBL1392281 AC50 311.0 nM
Cc1ccc(N/N=C2\CCS(=O)(=O)c3sccc32)cc1 CHEMBL3211664 AC50 311.0 nM
O=C1N=C(c2ccccc2)C(c2ccccc2)N1 CHEMBL1529823 AC50 318.0 nM
Cc1ccc(S(=O)(=O)NNc2ccccc2)c(C)c1 CHEMBL1350506 AC50 319.0 nM
O=C1CC(NNc2ccccc2)C(=O)N1c1cccc(Cl)c1 CHEMBL1420412 AC50 319.0 nM
Cc1ccc(N2NC(=O)/C(=C\c3cc4c(cc3[N+](=O)[O-])OCO4)C2=O)cc1C CHEMBL1309568 AC50 321.0 nM
C/C(=C\c1ccc(N)cc1)c1nc2ccccc2[nH]1 CHEMBL1452933 AC50 321.0 nM
Oc1cnnc(Nc2ccc(Nc3ccccc3)cc2)n1 CHEMBL1407882 AC50 323.0 nM
Oc1[nH]c2ccccc2c1C1=NCCCC1 CHEMBL1562995 AC50 325.0 nM
COc1ccc(-c2cn3c4c(sc3n2)CCCC4)cc1 CHEMBL194594 AC50 325.0 nM
Nc1n[nH]c(N2CCN(c3ccc(Cl)cc3)CC2)n1 CHEMBL1468967 AC50 325.0 nM
CCN(CC)c1ccc(NC(=O)c2cccnc2)cc1 CHEMBL1332872 AC50 327.0 nM
CCCS(=O)(=O)N1CCCC(C(=O)NCCN(CC)c2ccccc2)C1 CHEMBL1520203 AC50 330.0 nM
COc1cc(/C=N/NC(=O)C(C)n2nnc3ccccc32)ccc1O CHEMBL3190975 AC50 332.0 nM
Oc1ccc(/C(Cc2ccccn2)=N\Nc2ccccc2)c(O)c1 CHEMBL3190152 AC50 332.0 nM
O=C1CSC(NC(=O)N2c3ccccc3Sc3ccccc32)=N1 CHEMBL1527022 AC50 335.0 nM
CC(=O)Nc1ccc2c(c1)nc1n2CCSC1 CHEMBL1506094 AC50 340.0 nM
Nc1cc(C(=O)O)ccc1Nc1ccc(F)c(F)c1 CHEMBL1358818 AC50 345.0 nM
CC(C(=O)NC1C=CS(=O)(=O)C1)N1C(=O)/C(=C\c2ccccc2)SC1=S CHEMBL1346705 AC50 359.0 nM
CC(NC(=O)C1CC1)C(c1cccs1)N1CCN(c2ccccc2)CC1 CHEMBL1722578 AC50 362.0 nM
CC(CN1c2ccccc2Sc2ccccc21)N(C)C CHEMBL1200750 AC50 367.0 nM
Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1 CHEMBL715 AC50 369.0 nM
O=C1CC(NNc2ccccc2)C(=O)N1c1ccccc1 CHEMBL1510485 AC50 382.0 nM
CCN(CC)c1ccc(NS(=O)(=O)c2ccc(-c3ccc(O)nn3)o2)c(C)c1 CHEMBL1588970 AC50 382.0 nM
CCN(CC)c1ccc(NC(=O)CN2CCN(c3ccccn3)CC2)cc1 CHEMBL1368543 AC50 384.0 nM
Cn1c(-c2ccc3nc(N)sc3c2)nc2cc(N)ccc21 CHEMBL1468601 AC50 384.0 nM
O=C(Nc1ccc(-c2nnc(S)o2)cc1)c1cccc(Br)c1 CHEMBL1590193 AC50 386.0 nM
O=C(c1cccc(C(F)(F)F)c1)C1CCCN(C(=O)c2cc(C3CC3)[nH]n2)C1 CHEMBL1375445 AC50 392.0 nM
Cc1ccc2occ(C3N[C@H](C(=O)O)CS3)c(=O)c2c1 CHEMBL1564951 AC50 392.0 nM
COc1cc(/C=N/NC(=O)c2cc3ccccc3[nH]2)ccc1O CHEMBL3186069 AC50 393.0 nM
COc1cc(NC(=O)CN2c3ccccc3CC2C)cc(OC)c1OC CHEMBL1464800 AC50 394.0 nM
CCN(CCNC(=O)C1CCCN(S(=O)(=O)c2c[nH]cn2)C1)c1ccccc1 CHEMBL1558470 AC50 394.0 nM
O=C1CSC(c2ccccn2)N1c1cccc(Cl)c1 CHEMBL1341099 AC50 394.0 nM
Cn1c(=O)c2nc(Nc3ccccc3)[nH]c2n(C)c1=O CHEMBL1449587 AC50 398.0 nM
CN(CCCNC(=O)C1CCC(=O)N1Cc1ccccc1Cl)c1ccccc1 CHEMBL1490634 AC50 398.0 nM
COc1cc(/C=N/O)ccc1OS(=O)(=O)c1ccc(C)cc1 CHEMBL3211656 AC50 401.0 nM
CC1=NN2C(=N)/C(=C\c3cc(C)n(Cc4ccccc4)c3C)C(=O)N=C2S1 CHEMBL1520050 AC50 405.0 nM
O=C(O)Cn1cc(C(=S)N2CCCCC2)c2ccccc21 CHEMBL1363799 AC50 407.0 nM
CCn1c(=O)c(=O)[nH]c2cc(C(=O)NC(C)c3ccc(S(N)(=O)=O)cc3)ccc21 CHEMBL1537389 AC50 407.0 nM
COc1cc(/C=N/NC(=O)c2cc(-c3ccc4c(c3)OCO4)[nH]n2)ccc1O CHEMBL3192164 AC50 408.0 nM
Cc1cc(Oc2ncccc2[N+](=O)[O-])c2cc(Cl)ccc2n1 CHEMBL1312131 AC50 409.0 nM
CCN(CC)c1ccc(NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)c(C)c1 CHEMBL1410058 AC50 409.0 nM
COc1cc(/C=C2/C(=O)NN(c3ccc(Cl)c(Cl)c3)C2=O)cc([N+](=O)[O-])c1O CHEMBL1605103 AC50 409.0 nM
O=C(c1ccco1)N1CCN=C1SCc1ccccc1Cl CHEMBL1429819 AC50 410.0 nM
COc1ccc(-c2c[nH]nc2N)c(OC)c1 CHEMBL1441773 AC50 411.0 nM
CC(=O)N/N=C/c1cc(C)n(-c2ccc(Br)cc2)c1C CHEMBL3209009 AC50 414.0 nM
CN(C)c1ccc(/C=C/c2cc[n+](C)cc2)cc1 CHEMBL1368428 AC50 416.0 nM
O=C(Nc1ccc(N2CCCCCC2)cc1)c1ccc[nH]1 CHEMBL1435749 AC50 420.0 nM
C[n+]1c2n(c3ccccc31)N=C(c1ccc(Cl)cc1)CS2 CHEMBL1385794 AC50 425.0 nM
Clc1ccc(N/N=C/c2cccnc2)cc1 CHEMBL3196840 AC50 426.0 nM
CCN(CC)c1ccc(NC(=O)C2CC3CCC2C3)cc1 CHEMBL1385837 AC50 431.0 nM
[O-][n+]1ccccc1S CHEMBL1356238 AC50 432.0 nM
O=C(c1cccc(F)c1)N1CCC(c2nc3ccccc3s2)CC1 CHEMBL1390628 AC50 433.0 nM
CNc1nc(N)c(C(=O)C23CC4CC(CC(C4)C2)C3)s1 CHEMBL1562264 AC50 437.0 nM
O=C1NC(=O)N(Cc2ccc(F)cc2)C(=O)/C1=C/NNc1ccccc1 CHEMBL1600756 AC50 438.0 nM
O=C(N/N=C/c1ccc(O)c(O)c1)C1c2ccccc2Oc2ccccc21 CHEMBL3199413 AC50 439.0 nM
Cc1ccc(NNC(=O)c2ccno2)cc1C CHEMBL1388116 AC50 439.0 nM
CN(C)CCNC(=O)C(=O)NCC(c1ccc2c(c1)OCO2)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1698633 AC50 439.0 nM
CC(=O)Nc1ccc(SCc2ncc(-c3ccccc3)o2)cc1 CHEMBL1383996 AC50 440.0 nM
CCc1ccc(CNc2ccc(N3CCN(C(C)=O)CC3)cc2)cc1 CHEMBL1408033 AC50 445.0 nM
CC1CCN(CC(=O)Nc2ccc(N3CCCCCC3)cc2)CC1 CHEMBL1477039 AC50 448.0 nM
O=C1NC(=O)N(c2ccccc2)C(=O)/C1=C/C=C/c1ccco1 CHEMBL1418103 AC50 449.0 nM
CCN(CC)c1ccc(/C=C/c2cccc[n+]2C)c(OC)c1 CHEMBL1382191 AC50 452.0 nM
CCN(CC)c1ccc(/C=N/Nc2nc(C)cc(O)n2)cc1 CHEMBL3190647 AC50 456.0 nM
CC1CC(N(C(=O)c2ccco2)c2ccccc2)c2ccccc2N1 CHEMBL1372336 AC50 465.0 nM
C=CCc1cc(/C=C/c2nc(O)c([N+](=O)[O-])c(O)n2)cc(OC)c1O CHEMBL1307247 AC50 469.0 nM
Cc1ccc(-c2nn(-c3ccccc3)cc2CN(Cc2ccccc2)C(=O)CCC(=O)O)o1 CHEMBL1412664 AC50 471.0 nM
CC(=O)c1cccc(Oc2cc(NN3CCCCC3)c([N+](=O)[O-])cc2[N+](=O)[O-])c1 CHEMBL1596420 AC50 471.0 nM
CN1CC(=O)N(CC(=O)Nc2ccc(SC(F)F)cc2)C1=O CHEMBL1710197 AC50 477.0 nM
Cc1nc(C(=O)N2CCCC(Nc3ccc(C)c(C)c3)C2)cs1 CHEMBL1299433 AC50 479.0 nM
COc1ccc(/C=N/Nc2ccccn2)c(OC)c1OC CHEMBL3209990 AC50 484.0 nM
COc1cc(/C=C2/C(=O)NN(c3ccccc3)C2=O)cc(Br)c1O CHEMBL1489115 AC50 484.0 nM
Cc1occc1C(=O)NCCCCc1ccccc1 CHEMBL1385638 AC50 488.0 nM
NC(=NO)c1cn(Cc2ccccc2Cl)c2ccccc12 CHEMBL1467908 AC50 488.0 nM
COc1c2ccoc2nc2c(OC)c(O)ccc12 CHEMBL455007 AC50 490.0 nM
O=C(CN1C(=O)C2CC=CCC2C1=O)Nc1nc2ccc(F)cc2s1 CHEMBL1494549 AC50 494.0 nM
Cc1ccc(/C=C2\C(=O)NC(=O)N(Cc3ccccc3Cl)C2=O)o1 CHEMBL1548074 AC50 494.0 nM
COc1cc(/C=N/N2C(C)CCCC2C)cc(Br)c1O CHEMBL3210526 AC50 495.0 nM
[O-][n+]1onc2c3c4c(n(O)c3ccc21)CCCC4 CHEMBL1468104 AC50 497.0 nM
CCC(=O)Nc1ccc(SC#N)cc1C CHEMBL1455660 AC50 497.0 nM
Cc1cc(C)cc(N2C(=O)NC(=O)/C(=C\C=C\c3ccco3)C2=O)c1 CHEMBL1335687 AC50 501.0 nM
COc1ccc([N+](=O)[O-])c(S(=O)(=O)c2ccccc2)n1 CHEMBL213580 AC50 501.0 nM
O=C(NCc1ccc2c(c1)OCO2)c1nc(S(=O)(=O)Cc2ccccc2)ncc1Cl CHEMBL1585742 AC50 505.0 nM
C=CCN1C(=O)NC(=O)/C(=C\c2ccc(-c3ccccc3[N+](=O)[O-])o2)C1=O CHEMBL1390246 AC50 507.0 nM
CCN(CCNC(=O)c1cccc(N2CCCC2=O)c1)c1ccccc1 CHEMBL1384300 AC50 508.0 nM
Nc1cc([N+](=O)[O-])ccc1Nc1ccccc1 CHEMBL1492242 AC50 509.0 nM
Nc1nc(C2CC2)c(Sc2sc(N)nc2C2CC2)s1 CHEMBL1335881 AC50 511.0 nM
O=C(NCc1ccccn1)c1ccc2c(c1)N(Cc1ccccc1)CCS2 CHEMBL1539508 AC50 511.0 nM
COc1ccc(Nc2c3c(nc4ccccc24)CCCC3)cc1OC CHEMBL1422970 AC50 511.0 nM
Cc1ccc(-c2cn3c(n2)SCC3)cc1 CHEMBL1323486 AC50 513.0 nM
Nc1ccc(NC(=O)c2cccs2)cc1 CHEMBL1567637 AC50 515.0 nM
CC(=O)Nc1ccc(N2C(=O)CSC2c2ccccc2[N+](=O)[O-])cc1 CHEMBL1574229 AC50 517.0 nM
CCN1/C(=C/C=C/c2sc3ccccc3[n+]2CC)Sc2ccccc21 CHEMBL81782 AC50 522.0 nM
CN1C(=O)/C(=C/c2cccc([N+](=O)[O-])c2)C(=O)N1c1ccccc1 CHEMBL1422185 AC50 533.0 nM
C/C(=N\Nc1cccc(Cl)c1)c1ccncc1 CHEMBL3212126 AC50 536.0 nM
Oc1ccc(/C=N/N=C/c2ccc(O)c(O)c2)cc1O CHEMBL1968928 AC50 543.0 nM
Cc1nnc(SCc2cnc(-c3ccccc3)o2)nc1O CHEMBL1419835 AC50 547.0 nM
O=C(NC1CC1)c1ccc(CSCc2ccccc2Cl)o1 CHEMBL585651 AC50 549.0 nM
O=C(c1ccccc1F)N1CCN=C1SCc1cccnc1 CHEMBL1453312 AC50 552.0 nM
Nc1ccc(-c2nc3c(Cl)cc(N)cc3[nH]2)cc1 CHEMBL1301573 AC50 556.0 nM
Cc1ccn2cc(-c3ccc(O)c(O)c3)nc2c1 CHEMBL1519731 AC50 558.0 nM
CCc1nc(SCc2cccnc2)nc(O)c1C CHEMBL1361898 AC50 563.0 nM
Sc1nnc(-c2ccccc2)c(-c2ccccc2)n1 CHEMBL95862 AC50 567.0 nM
CC(=O)N1CCN(c2ccc(NCc3ccccc3)cc2)CC1 CHEMBL1415169 AC50 570.0 nM
COc1c(O)cc2oc(-c3ccc(O)cc3)cc(=O)c2c1O CHEMBL293776 AC50 572.0 nM
O=C1OC(Nc2ccc3c(c2)OCO3)c2ccccc21 CHEMBL1518540 AC50 577.0 nM
CCCc1nc2ccccc2c(=O)n1/N=C/c1ccc(O)c(O)c1 CHEMBL3214200 AC50 577.0 nM
Cc1c(Br)cnn1C(C)C(=O)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1705882 AC50 578.0 nM
CC(=O)NNc1nc(-c2ccc(NC(C)=O)cc2)cs1 CHEMBL1587421 AC50 580.0 nM
COc1ccc2[nH]c(S)nc2c1 CHEMBL1509639 AC50 581.0 nM
O=C(NC1=NCCS1)c1csc2ccccc12 CHEMBL1442502 AC50 582.0 nM
Oc1c(Cl)cc(Cl)cc1CNc1nc2ccccc2[nH]1 CHEMBL1352254 AC50 587.0 nM
Nc1cccc(/C=C/c2ccncc2)c1 CHEMBL3193752 AC50 590.0 nM
c1ccc(-c2nc(-c3ccco3)cs2)nc1 CHEMBL1419870 AC50 593.0 nM
c1ccc(NNC2=NCCCCC2)cc1 CHEMBL1325346 AC50 596.0 nM
Cc1ccc(-n2cccc2/C=C2/C(=N)N3C(=NC2=O)SN=C3S(C)(=O)=O)cc1 CHEMBL1340228 AC50 598.0 nM
CCS(=O)(=O)Nc1c(C(=O)O)[nH]c2ccccc12 CHEMBL1362624 AC50 600.0 nM
CC(C)=NNc1nc(-c2ccccc2)cs1 CHEMBL1508937 AC50 601.0 nM
Cc1ccn2cc(-c3cccc(NC(=O)CCC(=O)O)c3)nc2c1 CHEMBL1321420 AC50 618.0 nM
CCc1nc(SCc2ccc(F)cc2)nc(O)c1C#N CHEMBL1563536 AC50 622.0 nM
Cc1ccc(S(=O)(=O)NNc2ccccc2)cc1 CHEMBL1330954 AC50 623.0 nM
CC1CC/C(=N/Nc2ccccc2)C(=O)N1 CHEMBL3190156 AC50 623.0 nM
Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3oc4ccc(Cl)cc4c3C)cc2)c1C CHEMBL1564636 AC50 626.0 nM
Cn1c(=O)c2c(nc(N/N=C/c3ccncc3)n2Cc2ccccc2)n(C)c1=O CHEMBL3189888 AC50 628.0 nM
Cc1ccc(C(=O)Nc2ccccc2C(=O)O)cc1S(=O)(=O)Nc1ccc(Br)cc1 CHEMBL1725519 AC50 628.0 nM
CC(=O)N1CCN=C1SCc1c(F)cccc1Cl CHEMBL1419560 AC50 631.0 nM
COc1cc(/C=N/N2CCCCC2)cc(OC)c1O CHEMBL3195310 AC50 639.0 nM
O=C(N/N=C\c1cccc(Cl)c1)c1ccc(Cn2cccn2)o1 CHEMBL3193233 AC50 641.0 nM
Cc1cc(N2CCCC2)ccc1NC(=O)CN1C(=O)NC2(CCCCC2)C1=O CHEMBL1435811 AC50 644.0 nM
O=P(CN1CCN(c2ccccc2)CC1)(N1CCCCC1)N1CCCCC1 CHEMBL1305204 AC50 656.0 nM
O=C(CN1CCN(c2ccc(Cl)cc2)CC1)N1CCCC1 CHEMBL1385257 AC50 657.0 nM
Cc1[nH]c2ccccc2c1N=Nc1cccc(C(=O)O)c1 CHEMBL1504067 AC50 663.0 nM
Sc1nccc(-c2cccs2)n1 CHEMBL1577873 AC50 664.0 nM
CNc1ccc(C2(O)C(=O)c3ccccc3C2=O)cc1 CHEMBL1720415 AC50 664.0 nM
Cc1[nH]c2ccc(-c3nnc(S)n3C)cc2c1C CHEMBL1347556 AC50 664.0 nM
CCc1nn(C)c(-c2nnc(S)n2N)c1Cl CHEMBL1488098 AC50 673.0 nM
Cc1[nH]n(C(N)=S)c(=O)c1/N=N/c1ccc(Cl)cc1Cl CHEMBL3145365 AC50 674.0 nM
CC1(c2ccccc2)NC(=O)N(CC(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)C1=O CHEMBL1433997 AC50 675.0 nM
Cc1ccc(C(=O)Nc2nc(-c3ccc([N+](=O)[O-])cc3)cs2)o1 CHEMBL1391172 AC50 675.0 nM
Nc1ccc(Oc2cccc(Oc3ccc(N)cc3)c2)cc1 CHEMBL1332684 AC50 677.0 nM
O=C1CC(N2CCc3ccccc32)C(=O)N1c1ccccc1 CHEMBL1589467 AC50 677.0 nM
CCN(CCCNC(=O)C1CCC(=O)N1Cc1ccc(C)cc1)c1cccc(C)c1 CHEMBL1582027 AC50 677.0 nM
c1csc(-c2nc3ccccn3c2NC2CCCCC2)c1 CHEMBL1425603 AC50 678.0 nM
N#Cc1ccc(CSc2nnc(NC(=O)c3ccc(O)nc3)s2)cc1 CHEMBL1363086 AC50 679.0 nM
CCN(CC)c1ccc(CNc2nc3ccccc3n2CCN2CCCCC2)cc1 CHEMBL1531172 AC50 680.0 nM
COc1ccc(/C=N/NC(=O)c2cc[nH]n2)cc1CSc1ccccn1 CHEMBL3194203 AC50 680.0 nM
COc1cc(SC)ccc1C(=O)N1CCN(c2ccc(O)cc2)CC1 CHEMBL1430557 AC50 680.0 nM
CC(=O)Nc1ccc(SC[C@H](C)CN2CC[C@H](C(C)(C)C)CCC2=O)cc1 CHEMBL1457360 AC50 687.0 nM
O=C1CSC(c2ccccc2[N+](=O)[O-])N1c1cccc(F)c1 CHEMBL1429255 AC50 689.0 nM
Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 CHEMBL69863 AC50 689.0 nM
Cc1cc(C)c(S(=O)(=O)Nc2ccc(O)cc2)c(C)c1 CHEMBL1411518 AC50 694.0 nM
O=C(NNCc1ccc(O)cc1)c1ccccc1Cl CHEMBL1728840 AC50 695.0 nM
O=C(CN1CCN(c2ccc(O)cc2)CC1)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1705550 AC50 699.0 nM
O=C(O)c1ccccc1NC(=O)c1cc(-c2ccccc2)nc2ccccc12 CHEMBL1545389 AC50 703.0 nM
Cc1cc(S(=O)(=O)Nc2ccc(N(C)C)cc2)c(C)s1 CHEMBL1483284 AC50 704.0 nM
Cc1ccc(Nc2c(-c3ccccc3O)nc3cnccn23)cc1 CHEMBL1458203 AC50 705.0 nM
CC(C)c1ccc(NC2CCCN(C(=O)c3cc(C(C)C)nc(N)n3)C2)cc1 CHEMBL1724886 AC50 714.0 nM
Cc1ccc(Oc2ccc(S(=O)(=O)Nc3ccc(C(=O)O)cc3)cc2)cc1 CHEMBL1731659 AC50 714.0 nM
CNc1nnc(CSc2nc3ccccc3s2)s1 CHEMBL1561532 AC50 714.0 nM
Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1 CHEMBL1564800 AC50 719.0 nM
Cc1c(C(=O)N(C)C)c2cc(Cl)ccc2n1O CHEMBL1502225 AC50 722.0 nM
O=S(=O)(Nc1ccc(N2CCCCC2)cc1)c1cccc2cccnc12 CHEMBL1602070 AC50 723.0 nM
CCN(CCCNC(=O)CNC(=O)Cn1cnc2ccccc2c1=O)c1ccccc1 CHEMBL1334679 AC50 729.0 nM
CC(C)CN1C(=O)NC(NS(=O)(=O)c2ccc(N)cc2)(C(F)(F)F)C1=O CHEMBL1713525 AC50 730.0 nM
NC(=O)c1ccc(CSc2nc3ccccc3s2)cc1 CHEMBL1345289 AC50 730.0 nM
Cc1ccc(NC(NC(=O)c2ccccn2)C(Cl)(Cl)Cl)cc1 CHEMBL1569284 AC50 731.0 nM
Cc1cc(C)cc(N2C(=O)CSC2c2ccccn2)c1 CHEMBL1483455 AC50 731.0 nM
Cc1ccc(-c2csc(N)n2)s1 CHEMBL1550451 AC50 732.0 nM
Cc1nc2ccc(-c3nc4cc(N)ccc4[nH]3)cc2[nH]1 CHEMBL525103 AC50 736.0 nM
CC(=O)Nc1ccc(NC2CCCCC2NS(=O)(=O)c2ccccc2)cc1 CHEMBL1712627 AC50 736.0 nM
O=[N+]([O-])c1c(O)nc(/C=C\c2cccc(Cl)c2)nc1O CHEMBL1613189 AC50 737.0 nM
O=C(NNc1c2ccccc2nc2ccccc12)c1cccc(O)c1 CHEMBL1351342 AC50 738.0 nM
CCN(CC)c1ccc(CNCc2cccs2)cc1 CHEMBL1556476 AC50 742.0 nM
CC(=O)N1CCN(c2ccc(NCc3ccc(Br)o3)cc2)CC1 CHEMBL1354816 AC50 743.0 nM
CCN(CC)c1ccc(NC(=O)c2ccc(Br)o2)cc1 CHEMBL1331097 AC50 745.0 nM
CC(C)(C)c1ccc(-c2nc3cc(N)ccc3o2)cc1 CHEMBL1341926 AC50 751.0 nM
Cc1nc(N)sc1N=Nc1ccc(Br)cc1 CHEMBL1471700 AC50 753.0 nM
CCn1c(=O)n(CC)c2cc(N)ccc21 CHEMBL1466601 AC50 754.0 nM
Cn1cnnc1SCc1ccc(C(=O)N/N=C(\CCC(=O)O)c2ccc(C(C)(C)C)cc2)cc1 CHEMBL3191285 AC50 755.0 nM
COc1ccc(Nc2c(-c3ccc(C)cc3)nc3cnccn23)cc1 CHEMBL1305451 AC50 763.0 nM
[O-][S+](c1ccc2ccccc2c1)c1cnns1 CHEMBL1459259 AC50 769.0 nM
COc1ccc(/C=N/Nc2ccccn2)cc1OC CHEMBL3191000 AC50 771.0 nM
c1ccc(Nc2ccccc2Nc2ccccn2)nc1 CHEMBL1368821 AC50 773.0 nM
CCn1c(C)cc(/C=C2/SC(=S)N(CC(=O)O)C2=O)c1C CHEMBL1540680 AC50 776.0 nM
COc1cc(/C=C/c2ccc(O)cc2)cc(OC)c1 CHEMBL83527 AC50 778.0 nM
CCN(CC)S(=O)(=O)c1ccc(/N=N/c2c(C)[nH]n(C(N)=S)c2=O)cc1 CHEMBL3145369 AC50 782.0 nM
COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2C)c(OC)c1C CHEMBL367741 AC50 784.0 nM
O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 CHEMBL1393131 AC50 785.0 nM
O=C(NNc1ccccn1)C(=O)NNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL1409617 AC50 786.0 nM
CC(=O)N1CCN(c2ccc(NCc3cccc(C)c3)cc2)CC1 CHEMBL1704789 AC50 787.0 nM
CCN(CC)c1ccc(NS(=O)(=O)c2cn(C)c(=O)n(C)c2=O)c(C)c1 CHEMBL1395951 AC50 789.0 nM
COc1ccc(-c2cc(-c3ccc(N)cc3)nc(N)c2C#N)cc1OC CHEMBL1307432 AC50 794.0 nM
NC(=O)NC(=O)C(Nc1ccc(N2CCCCC2)cc1)c1ccccc1 CHEMBL1398590 AC50 797.0 nM
O=C(N/N=C/c1cccc(O)c1)N/N=C/c1cccc(O)c1 CHEMBL3196316 AC50 797.0 nM
Sc1nnc(-c2ccco2)n1/N=C/C(Cl)=C/c1ccccc1 CHEMBL2002332 AC50 798.0 nM
Nc1ccc(-c2cc(N)n(-c3ccccc3)n2)cc1 CHEMBL1362056 AC50 800.0 nM
Cc1cc(Sc2nnc(/N=C/N(C)C)s2)c2ccccc2n1 CHEMBL1981002 AC50 801.0 nM
Nc1ccc(N2CCN(c3ccc(F)cc3)CC2)cc1 CHEMBL1362893 AC50 821.0 nM
CN(C)c1ccc(CN(Cc2ccco2)C(=O)c2ccco2)cc1 CHEMBL1588746 AC50 822.0 nM
CN(CCCNC(=O)c1cccc(N2CCCC2=O)c1)c1ccccc1 CHEMBL1488901 AC50 823.0 nM
CCN(CC)c1ccc(/C=N\NC(N)=O)cc1 CHEMBL3213363 AC50 825.0 nM
O=C1Nc2ccccc2/C1=N/N=C/c1ccc(O)c(O)c1 CHEMBL607979 AC50 830.0 nM
COc1ccc(S(=O)(=O)N/N=C(/C)c2ccncc2)c(OC)c1 CHEMBL3195917 AC50 832.0 nM
CN(C)NC(=O)c1ccsc1NC(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1440054 AC50 835.0 nM
COc1ccc(/C=N/Nc2ccc(C(=O)O)cc2)cc1Br CHEMBL3190653 AC50 837.0 nM
Cc1ccc2[nH]c(-c3cccc(N)c3)nc2c1 CHEMBL1527186 AC50 838.0 nM
Nc1ccc(-c2nc3ccc(C(=O)O)cc3s2)cc1 CHEMBL1468011 AC50 839.0 nM
CCN(CC)c1ccc(NC(=O)c2c(OC)cccc2OC)c(C)c1 CHEMBL1547699 AC50 840.0 nM
C[C@H](N)CN1CCc2ccc(Br)cc21 CHEMBL1256648 AC50 840.0 nM
O=C(Nc1cccc([N+](=O)[O-])c1)c1[nH]ncc1Cl CHEMBL1391443 AC50 847.0 nM
CCCC(=O)Nc1ccc(-c2csc(NNC(C)=O)n2)cc1 CHEMBL1459961 AC50 859.0 nM
Oc1ccc(/C=N/n2cc(-c3ccccc3)nc2S)cc1 CHEMBL1979530 AC50 860.0 nM
COc1cc(/C=N/n2c(C)nnc2S)ccc1OCc1ccccc1 CHEMBL3208621 AC50 861.0 nM
COc1cc(SC)ccc1C(=O)Nc1c(Cl)cncc1Cl CHEMBL1430126 AC50 867.0 nM
N#CCC(=O)Nc1ccc(C(=O)Nc2cccnc2)cc1 CHEMBL1733170 AC50 870.0 nM
O=C(Nc1ccc(Nc2ccccc2)cc1)C1CC1 CHEMBL1489834 AC50 875.0 nM
CCN(CC)c1ccc(NC(=O)c2cccnc2)c(C)c1 CHEMBL1605436 AC50 877.0 nM
O=C(NN=C1CCC(=NNC(=O)c2cccnc2)CC1)c1cccnc1 CHEMBL1508164 AC50 879.0 nM
Cc1ccc2nc(-c3ccc(O)c(O)c3)cn2c1 CHEMBL1300836 AC50 885.0 nM
COc1cc(/C=N/Nc2ccccc2)ccc1O CHEMBL304953 AC50 887.0 nM
CN(C)c1ccc(/C=C/c2nnnn2-c2ccccc2)cc1 CHEMBL1607208 AC50 894.0 nM
COc1ccc(Cc2nc3ccccc3n2CC(=O)N/N=C/c2ccc(O)cc2)cc1OC CHEMBL3190136 AC50 901.0 nM
COc1ccccc1NC(=O)Nc1ncccc1C CHEMBL1492549 AC50 903.0 nM
Sc1nc(-c2ccccc2)c[nH]1 CHEMBL1531403 AC50 904.0 nM
Cc1nn(-c2ccccc2)c(Cl)c1/C=N/Nc1ccc(Cl)c(C(=O)O)c1 CHEMBL3191171 AC50 907.0 nM
CCN(CC)c1ccc(/C=N/NC(=O)CNC(=O)c2ccccn2)cc1 CHEMBL3192488 AC50 910.0 nM
O=C(Nc1ccc2snnc2c1)N1CCN(c2ccccc2)CC1 CHEMBL1455653 AC50 913.0 nM
CC1CCN(C(=S)c2ccc(N(C)C)cc2)CC1 CHEMBL1491681 AC50 915.0 nM
NC(=O)Nc1ccc(Nc2ccccc2)cc1 CHEMBL1454784 AC50 916.0 nM
CCCCC(=O)NNC(=O)N1c2ccccc2Sc2ccccc21 CHEMBL1722434 AC50 919.0 nM
Cc1cc(C)c(S(=O)(=O)Nc2ccc(O)cc2)cc1C CHEMBL1594342 AC50 926.0 nM
COc1cc(/C=C2\SC(N3CCC(C)CC3)=NC2=O)ccc1O CHEMBL1462751 AC50 929.0 nM
O=C1CCCN1CCCNc1ncnc2c1[nH]c1ccc(Cl)cc12 CHEMBL1565575 AC50 943.0 nM
COc1ccc(CSc2nc(O)cc(=O)n2CC(C)C)cc1F CHEMBL1393850 AC50 949.0 nM
Nc1ccc2nc(NC(=O)C3CCCCC3)sc2c1 CHEMBL1391694 AC50 957.0 nM
COc1cccc(-c2noc(Cn3nc(C)c([N+](=O)[O-])c3C)n2)c1 CHEMBL1562643 AC50 983.0 nM
COc1cc(/C=N\Nc2nc3ccccc3[nH]2)cc(OC)c1OC CHEMBL3193000 AC50 997.0 nM