COc1cc(C)c(C)cc1S(=O)(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 CHEMBL1509159 Potency 5.6 nM
OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O CHEMBL110458 IC50 13.0 nM
NC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O CHEMBL3350086 IC50 53.0 nM
CC1CCCC(C)N1C(=O)Cc1ccccc1 CHEMBL1506331 Potency 63.1 nM
Cn1nc(C(F)(F)F)c(-c2ccccc2)c1NC(=O)c1nccnc1C(=O)O CHEMBL1505819 Potency 89.1 nM
Cc1ccc2nc(NCc3ccco3)c(/C=N/Cc3ccco3)c(=O)n2c1 CHEMBL1898790 Potency 100.0 nM
CCS(=O)(=O)c1cc([N+](=O)[O-])c(Sc2ccccc2N)s1 CHEMBL1422806 Potency 100.0 nM
CCOC(=O)C1=CN(C(=O)OC(C)(C)C)C(CN2C(=O)COCC2=O)C1 CHEMBL1591251 Potency 100.0 nM
CCCCOC(=O)c1ccc(NC(=O)C(=O)NCCN(C)C)cc1 CHEMBL1337610 Potency 100.0 nM
CCC(=O)CC(c1ccccc1)c1c([O-])c2ccccc2sc1=O CHEMBL1544563 Potency 100.0 nM
CN1C(=O)C(Cc2c[nH]c3ccccc23)NC1=S CHEMBL195008 Potency 112.2 nM
CCOc1cc(C(=O)Nc2ncccn2)cc(OCC)c1OCC CHEMBL1495385 Potency 158.5 nM
COc1cccc(CN2CCN(Cc3ccc4c(c3)OCCO4)CC2CCO)c1 CHEMBL1468715 Potency 158.5 nM
CCNc1ncc2nc(-c3ccccc3)c(=O)n(Cc3cccc(OC)c3)c2n1 CHEMBL1602568 Potency 158.5 nM
Cc1c(C(=O)NC(C(C)C)C(C)C)cccc1[N+](=O)[O-] CHEMBL1361851 Potency 177.8 nM
COCCCNC(=O)CCCn1c(=O)[nH]c2ccccc2c1=O CHEMBL1527829 Potency 177.8 nM
N#Cc1nc(COc2ccc(Br)cc2)oc1NCCN1CCOCC1 CHEMBL1414631 Potency 177.8 nM
O=C(NCc1ccc(F)cc1)c1cnc(-c2ccccn2)nc1C(F)(F)F CHEMBL1385184 Potency 177.8 nM
Nc1nc(NS(=O)(=O)c2ccccc2)nn1-c1ccccc1 CHEMBL1503116 Potency 177.8 nM
c1ccc(-n2ncc3c(NCc4cccnc4)ncnc32)cc1 CHEMBL1346258 Potency 177.8 nM
O=C(Oc1ccnc2cc(Cl)ccc12)N1CCCCCC1 CHEMBL1581772 Potency 177.8 nM
Cc1nc2ccc(NC(=O)NCCCO)cc2s1 CHEMBL1494572 Potency 177.8 nM
COc1ccc(/N=C2\SC(CC(=O)Nc3ccc(OC)cc3OC)C(=O)N2C)cc1 CHEMBL3208544 Potency 177.8 nM
CCOc1ccc(NC(=O)C2CC(=O)N=C(N3CCc4ccccc43)N2)cc1 CHEMBL1606610 Potency 177.8 nM
CCCN(CCC)CCc1c[nH]c2ccc(C(N)=O)cc12 CHEMBL1256720 Potency 177.8 nM
Cc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3sc4c(c3c2=O)CC(C)(C)SC4)cc1 CHEMBL1523038 Potency 177.8 nM
Cc1noc(/C=C/N(C)C)c1S(=O)(=O)N1CCC(C(=O)O)CC1 CHEMBL1326103 Potency 177.8 nM
Cc1nnc(-c2cccc(Br)c2)c2cn(-c3ccccc3Cl)nc12 CHEMBL1563819 Potency 177.8 nM
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 CHEMBL1700 Potency 177.8 nM
O=C1NC(c2ccccc2)Nc2c1sc(=S)n2-c1ccccc1 CHEMBL1341217 Potency 177.8 nM
Cc1nc2c(-c3ccccc3)c(C)nn2c(C)c1CCC(=O)O CHEMBL1401427 Potency 199.5 nM
CCc1nc(Cl)c(C#N)c2c1CCCC2 CHEMBL1306659 Potency 199.5 nM
O=C(NC(COCc1cn(CCOCCOc2ccc(-c3cn(C[C@H]4NC[C@@H](O)[C@H]4O)nn3)cc2)nn1)(COCc1cn(CCOCCOc2ccc(-c3cn(C[C@H]4NC[C@@H](O)[C@H]4O)nn3)cc2)nn1)COCc1cn(CCOCCOc2ccc(-c3cn(C[C@H]4NC[C@@H](O)[C@H]4O)nn3)cc2)nn1)c1cc(C(=O)NC(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)cc(C(=O)NC(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)(COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)COCc2cn(CCOCCOc3ccc(-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)cc3)nn2)c1 CHEMBL4792854 Ki 200.0 nM
C[C@]12CC(O)C3C(CCC4=CC(=O)CC[C@@]43C)C1CCC2c1csc(-c2ccccc2)n1 CHEMBL1502697 Potency 223.9 nM
CC1CN=C(Nc2ccccc2)S1 CHEMBL1600521 Potency 223.9 nM
Cc1ccccc1C(=O)NC1CCS(=O)(=O)C1 CHEMBL1529604 Potency 223.9 nM
CCC1Oc2ccc(C)cc2N(CC(=O)NCc2ccccc2OC)C1=O CHEMBL1568449 Potency 251.2 nM
CN1C(=O)N(C)C2(c3ccccc3)Nn3c(s/c(=C/c4ccco4)c3=O)=NC12c1ccccc1 CHEMBL3212680 Potency 251.2 nM
Cc1ccc(S(=O)(=O)N(CC#N)CC#N)cc1 CHEMBL1546078 Potency 281.8 nM
CCCc1c(O)c2ccccc2n(-c2ccccc2)c1=O CHEMBL1539061 Potency 316.2 nM
CC(C)(C)OC(=O)NCCc1nnc(S(=O)(=O)Cc2ccc(Cl)cc2Cl)o1 CHEMBL259018 Potency 316.2 nM
COc1ccc2c(c1)-c1c(sn(-c3ccccc3)c1=S)C(C)(C)N2 CHEMBL1601549 Potency 316.2 nM
Cc1ccc(OCCCC(=O)N2CCOCC2)c(C)c1 CHEMBL1366740 Potency 316.2 nM
CCCn1c(S)nnc1C(C)NC(=O)c1ccccc1 CHEMBL1352596 Potency 316.2 nM
O=C(CN1CCCCCC1)Nc1ccc(Oc2ccccc2)cc1 CHEMBL1390842 Potency 398.1 nM
O=C(c1ccc(Cl)cc1Cl)n1nnc2ccccc21 CHEMBL1394350 Potency 398.1 nM
CCOC(=O)N1CCN(C(=O)c2cccn3c(=O)c4cc(Cl)ccc4nc23)CC1 CHEMBL1427581 Potency 446.7 nM
Cc1ccc(S(=O)(=O)Nc2ccc(NC(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)cc1 CHEMBL1429822 Potency 446.7 nM
COc1ccc(N(C)S(=O)(=O)c2cccc(C(=O)OCC(=O)NCc3ccccc3OC)c2)cc1 CHEMBL1447352 Potency 446.7 nM
Cc1ccc(C)c(NC(=O)C2C3CCCC2C3c2ccccc2)c1 CHEMBL1589049 Potency 446.7 nM
Cc1c(NC(=O)C2CCCNC2=O)c(=O)n(-c2ccccc2)n1C CHEMBL1420200 Potency 446.7 nM
Cc1nc(NCCN2CCOCC2)c2oc3ccccc3c2n1 CHEMBL1381044 Potency 446.7 nM
OC[C@H]1N[C@H](CO)[C@@H](O)[C@H]1O CHEMBL469844 Ki 500.0 nM
CCN(c1cccc(C)c1)S(=O)(=O)c1cccc2nsnc12 CHEMBL1455398 Potency 501.2 nM
O=S(=O)(Nc1ccc(-c2nc3cccnc3s2)cc1)c1cccs1 CHEMBL1353698 Potency 562.3 nM
N#Cc1cc(-c2ccccc2)nc(Oc2ccccc2)n1 CHEMBL1300420 Potency 562.3 nM
CC(=O)N/C(=C/c1ccc2c(c1)OCO2)C(=O)NCCO CHEMBL1338859 Potency 707.9 nM
Cc1nc(O)nc(O)c1/C=N/NC(=O)[C@H](C)NC(=O)OC(C)(C)C CHEMBL3189967 Potency 707.9 nM
Cc1cc(O)cc(=O)o1 CHEMBL54907 Potency 794.3 nM
Cc1ccc(O)c(C2=NOC(O)(C(F)(F)C(F)F)C2)c1 CHEMBL1482983 Potency 794.3 nM
Cc1nc2oc3c(O)ncnc3c2c2c1COC(C)(C)C2 CHEMBL1465907 Potency 794.3 nM
COC(=O)c1ccc(Oc2nc(C(N)=O)cc(-c3ccccc3)n2)cc1 CHEMBL1466630 Potency 794.3 nM
CC1CN(S(=O)(=O)c2cccc(-c3cn4cccnc4n3)c2)CC(C)O1 CHEMBL1612476 Potency 794.3 nM
NC(=O)c1cccc2c(=O)oc3ccccc3c12 CHEMBL1372486 Potency 794.3 nM
CC(=O)Oc1ccc(N2C(=O)CCC2=O)cc1 CHEMBL1507269 Potency 794.3 nM
COc1ccc(-c2cc(C(F)(F)F)nc(-n3cncn3)n2)cc1 CHEMBL1536065 Potency 794.3 nM
COC(=O)c1sccc1N=C(S)N1CCCCC1 CHEMBL1586604 Potency 794.3 nM
CC(C)(N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O CHEMBL58547 Potency 794.3 nM
CCOc1ccc(Cn2c(=O)sc3ccccc32)cc1OC CHEMBL1367324 Potency 794.3 nM
Clc1cccc(-c2csc(Nc3cccnc3)n2)c1 CHEMBL1470189 Potency 794.3 nM
COc1ccc(-n2cnnc2SCC(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)cc1 CHEMBL1432073 Potency 794.3 nM
COC(=O)c1cc(Cl)c(NC(=O)/C=C/c2ccc(Cl)cc2Cl)cc1OC CHEMBL1511124 Potency 794.3 nM
O=S(=O)(NCC(c1ccccc1)N1CCNCC1)c1ccc(Cl)cc1 CHEMBL1492724 Potency 794.3 nM
CN(c1ccccc1)S(=O)(=O)c1ccccc1C(=O)Nc1nccs1 CHEMBL1447706 Potency 794.3 nM
Cc1ccc(/C=c2\sc3nc(-c4ccco4)nn3c2=O)o1 CHEMBL1976499 Potency 794.3 nM
Cc1cc(C)c(S(=O)(=O)N(C)CC(=O)NCc2ccccn2)c(C)c1 CHEMBL1556941 Potency 794.3 nM
CCCCCn1c(=O)c(C(=O)c2ccccc2)nc2ccccc21 CHEMBL1538481 Potency 891.3 nM
CSC1=NCCN1C(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1 CHEMBL1533042 Potency 891.3 nM
COC(=O)C(O)(c1cn(C)c2ccccc12)C(F)(F)F CHEMBL1544047 Potency 891.3 nM
CCS(=O)(=O)c1ccc2oc(SCC(=O)N3CCCCC3)nc2c1 CHEMBL1561231 Potency 891.3 nM
CC/C(NNC(=O)c1ccccc1O)=C1/C(=O)NC(=O)N(Cc2ccccc2)C1=O CHEMBL1505420 Potency 891.3 nM
CCN(C(=O)c1cn(C)c(=O)c2cc(OC)c(OC)cc12)c1cc(OC)ccc1OC CHEMBL1568538 Potency 891.3 nM
CCNc1ncc2nc(-c3cccc(C#N)c3)c(=O)n(C)c2n1 CHEMBL1554763 Potency 891.3 nM