O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(C[C@@H]2CC[C@H](c3nnc(NC(=O)Cc4ccccn4)s3)C2)nn1 CHEMBL4538736 IC50 0.1 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(C[C@H]2C[C@@H](c3nnc(NC(=O)Cc4ccccn4)s3)C2)nn1 CHEMBL4547874 IC50 0.2 nM
CO[C@@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cncnn3)C2)s1)c1cccc(OC(F)(F)F)c1 CHEMBL3810168 IC50 0.206 nM
CO[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cncnn3)C2)s1)c1ccccc1 CHEMBL3810394 IC50 0.39 nM
COc1ccc([C@H](OC)C(=O)Nc2nnc(N[C@@H]3CCN(c4cccnn4)C3)s2)cc1 CHEMBL3809014 IC50 0.4006 nM
Cn1ccc(CC(=O)Nc2nnc([C@H]3CC4(C[C@H](c5nnc(NC(=O)Cc6ccn(C)n6)s5)C4)C3)s2)n1 CHEMBL4454263 IC50 0.5 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)[se]2)nn1 CHEMBL4469040 IC50 1.0 nM
Cn1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)[se]2)c2ccccc21 CHEMBL4475144 IC50 1.0 nM
O=C(Cc1cccc(C(=O)O)c1)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1 CHEMBL5420669 INH 1.48 nM
CCCCS(=O)(=O)Cc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3680041 IC50 2.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)c4ccccc4)c3)s2)nn1 CHEMBL3675017 IC50 2.0 nM
CC(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675018 IC50 2.0 nM
O=C(Cc1ccccc1)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675020 IC50 2.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CC(=O)N4CCCC4)c3)s2)nn1 CHEMBL3675057 IC50 2.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)c4ccc(Br)nn4)c3)s2)nn1 CHEMBL3675059 IC50 2.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)nn1 CHEMBL3639788 IC50 2.0 nM
Cn1ccc(CC(=O)Nc2nnc([C@H]3CC4(C[C@H](c5nnc(NC(=O)Cc6ccn(C)n6)s5)C4)C3)s2)n1 CHEMBL4462146 IC50 2.7 nM
CCOC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3674968 IC50 3.0 nM
CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3674970 IC50 3.0 nM
CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(=O)Cc1ccccc1 CHEMBL3675029 IC50 3.0 nM
CC(=O)Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675036 IC50 3.0 nM
CCNC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675038 IC50 3.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CCNC(=O)c4ccccc4)c3)s2)nn1 CHEMBL3675040 IC50 3.0 nM
CCOC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675041 IC50 3.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)C(F)(F)F)c3)s2)nn1 CHEMBL3675043 IC50 3.0 nM
CC(C)CNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675054 IC50 3.0 nM
CC(C)(C)CNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675055 IC50 3.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CC(=O)N4CCC(F)(F)CC4)c3)s2)nn1 CHEMBL3675058 IC50 3.0 nM
CCCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675067 IC50 3.0 nM
CCCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675079 IC50 3.0 nM
CC(C)N(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675081 IC50 3.0 nM
CCCCNC(=O)Cc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3675099 IC50 3.0 nM
CC(C)CNC(=O)Cc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3675100 IC50 3.0 nM
CCOC(=O)NC(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675140 IC50 3.0 nM
CCOC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675141 IC50 3.0 nM
CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(CNC(=O)OCC)c4)s3)nn2)c1 CHEMBL3675150 IC50 3.0 nM
CC(C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)c1ccc(O)cc1 CHEMBL3675153 IC50 3.0 nM
CS(=O)(=O)CCCOc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679964 IC50 3.0 nM
CCCCS(=O)(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCC(=N)CCC(=N)NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679978 IC50 3.0 nM
CO[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3nccnn3)C2)s1)c1ccccc1 CHEMBL3808443 IC50 3.9 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(Cn4cccn4)c3)s2)nn1 CHEMBL3674980 IC50 4.0 nM
CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(=O)OC(C)(C)C CHEMBL3674981 IC50 4.0 nM
COc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc(OC)c1 CHEMBL3674983 IC50 4.0 nM
CC(C)(C)OC(=O)NCCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675014 IC50 4.0 nM
CC(=O)N(C)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675030 IC50 4.0 nM
CS(=O)(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675037 IC50 4.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CN4CCCCC4=O)c3)s2)nn1 CHEMBL3675060 IC50 4.0 nM
CC1(C)CCN(C(=O)Cc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2)C1 CHEMBL3675064 IC50 4.0 nM
CCCCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675066 IC50 4.0 nM
CC(C)CN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675068 IC50 4.0 nM
CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675069 IC50 4.0 nM
CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675080 IC50 4.0 nM
O=C(Cc1cccc(Cn2cccn2)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675083 IC50 4.0 nM
CCOC(=O)Cc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675084 IC50 4.0 nM
Cc1nccn1Cc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3675101 IC50 4.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(F)c(O)c3)s2)nn1 CHEMBL3675117 IC50 4.0 nM
CC(NC(=O)OC(C)(C)C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675120 IC50 4.0 nM
CC(C)(C)NC(=O)Cc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675121 IC50 4.0 nM
CC(NC(=O)OC(C)(C)C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675122 IC50 4.0 nM
CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675134 IC50 4.0 nM
CC(C)(C)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675142 IC50 4.0 nM
COC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(CNC(=O)OC)c4)s3)nn2)c1 CHEMBL3675151 IC50 4.0 nM
O=C(CC(O)C(F)(F)F)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675154 IC50 4.0 nM
CC(O)(CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(F)(F)F CHEMBL3675155 IC50 4.0 nM
COC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675165 IC50 4.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OCCF)c3)nn2)s1)c1ccccc1 CHEMBL3675167 IC50 4.0 nM
CCNC(=O)OC(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675168 IC50 4.0 nM
CC(NC(=O)C(F)(F)F)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679963 IC50 4.0 nM
CC(NC(=O)CC(F)(F)F)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679965 IC50 4.0 nM
CC(C)CC(=O)NC(C)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679966 IC50 4.0 nM
CC(NS(C)(=O)=O)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679967 IC50 4.0 nM
CC(C)(C)OC(=O)NC(C)(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3679971 IC50 4.0 nM
CC(C)CNC(=O)COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679980 IC50 4.0 nM
Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1 CHEMBL3679981 IC50 4.0 nM
O=C(Cc1cccc2c1CNC2)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 CHEMBL3679982 IC50 4.0 nM
Cc1nnc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)o1 CHEMBL3679985 IC50 4.0 nM
O=C(Cc1cccc(OC(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3679999 IC50 4.0 nM
O=C(Cc1cccc(OCC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3680000 IC50 4.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)nn1 CHEMBL3680003 IC50 4.0 nM
CO[C@@H](C(=O)Nc1nnc(NC2CCN(c3nnc(NC(=O)CCc4cn(CC5=CC=C(C(F)(F)F)CC5)nn4)s3)CC2)s1)c1ccccc1 CHEMBL5207321 IC50 4.85 nM
COc1cc([C@@H](OC)C(=O)Nc2nnc(N[C@@H]3CCN(c4cncnn4)C3)s2)ccc1F CHEMBL3809081 IC50 4.99 nM
C[C@@](O)(C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(F)(F)F CHEMBL3680034 IC50 5.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3670037 IC50 5.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3670071 IC50 5.0 nM
CC(C)(C)OC(=O)Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3674984 IC50 5.0 nM
CC(C)(C)OC(=O)NCc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3674986 IC50 5.0 nM
CN(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675019 IC50 5.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 CHEMBL3675032 IC50 5.0 nM
O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 CHEMBL3675033 IC50 5.0 nM
CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)c4ccccc4)c3)s2)nn1 CHEMBL3675045 IC50 5.0 nM
CC(C)(C)OC(=O)NCc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675049 IC50 5.0 nM
COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(O)c4cccc(Cl)c4)s3)nn2)c1 CHEMBL3675052 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CN4CCCC4=O)c3)s2)nn1 CHEMBL3675062 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CC(=O)N4CCC4)c3)s2)nn1 CHEMBL3675070 IC50 5.0 nM
CC(C)(C)NC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675078 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc4[nH]ncc34)s2)nn1 CHEMBL3675095 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(C(F)(F)F)c3)s2)nn1 CHEMBL3675125 IC50 5.0 nM
COc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1C CHEMBL3675129 IC50 5.0 nM
COC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675132 IC50 5.0 nM
CCOc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1O CHEMBL3675135 IC50 5.0 nM
O=C(Cc1ccccc1Cl)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3Cl)s2)nn1 CHEMBL3675143 IC50 5.0 nM
CC1(C)OCC(C)(C(=O)NCc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2)CO1 CHEMBL3675156 IC50 5.0 nM
COc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1O CHEMBL3675158 IC50 5.0 nM
CS(=O)(=O)CCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675159 IC50 5.0 nM
CC(O)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675169 IC50 5.0 nM
CC(O)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(OC(F)(F)F)c4)s3)nn2)c1 CHEMBL3675173 IC50 5.0 nM
CC(C)NC(=O)OC(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675174 IC50 5.0 nM
CCOC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)s2)c1 CHEMBL3675176 IC50 5.0 nM
CCNC(=O)OC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675186 IC50 5.0 nM
COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(OC(F)(F)F)c4)s3)nn2)c1 CHEMBL3679958 IC50 5.0 nM
CC(C)C(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679961 IC50 5.0 nM
CCC(=O)NC(C)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679962 IC50 5.0 nM
CC(C)(C)OC(=O)NC(C)(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679972 IC50 5.0 nM
CS(=O)(=O)Cc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679976 IC50 5.0 nM
CC(NC(=O)OC(C)(C)C)c1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F CHEMBL3679986 IC50 5.0 nM
CC(NC(=O)OC(C)(C)C)c1cc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)ccc1F CHEMBL3679987 IC50 5.0 nM
COc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)s2)c1 CHEMBL3679991 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)F)c3)s2)nn1 CHEMBL3679997 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCC(F)(F)F)c3)s2)nn1 CHEMBL3679998 IC50 5.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 CHEMBL3670017 IC50 6.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Br)c3)s2)nn1 CHEMBL3675000 IC50 6.0 nM
CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)s2)nn1 CHEMBL3675009 IC50 6.0 nM
CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CN)c3)s2)nn1 CHEMBL3675010 IC50 6.0 nM
CC(C(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)s2)nn1)c1ccccc1 CHEMBL3675021 IC50 6.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(Oc4ccccc4)c3)s2)nn1 CHEMBL3675035 IC50 6.0 nM
CC(=O)NCCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675039 IC50 6.0 nM
CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)Cc4ccccc4)c3)s2)nn1 CHEMBL3675047 IC50 6.0 nM
O=C(O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675050 IC50 6.0 nM
CN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675056 IC50 6.0 nM
CC(C)(C)OC(=O)NCc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F CHEMBL3675075 IC50 6.0 nM
O=C(Cc1ccccc1Cl)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675104 IC50 6.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3Cl)nn2)s1 CHEMBL3675110 IC50 6.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3F)nn2)s1 CHEMBL3675111 IC50 6.0 nM
Cc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3F)nn2)s1 CHEMBL3675115 IC50 6.0 nM
COc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1F CHEMBL3675123 IC50 6.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(Cl)c3F)s2)nn1 CHEMBL3675124 IC50 6.0 nM
CCOc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1OC CHEMBL3675126 IC50 6.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(F)c(Cl)c3)s2)nn1 CHEMBL3675128 IC50 6.0 nM
CCCOc1ccc(C(O)C(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3675137 IC50 6.0 nM
O=C(Cc1ccccc1F)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3Cl)s2)nn1 CHEMBL3675144 IC50 6.0 nM
CN(Cc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F)C(=O)OC(C)(C)C CHEMBL3675147 IC50 6.0 nM
CCOC(=O)NCc1cc(C(C)C(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F CHEMBL3639740 IC50 6.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675161 IC50 6.0 nM
COC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675177 IC50 6.0 nM
CCOC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675178 IC50 6.0 nM
CC(O)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675187 IC50 6.0 nM
CS(=O)(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3679975 IC50 6.0 nM
CC(=O)N1Cc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2C1 CHEMBL3679984 IC50 6.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)nn1 CHEMBL3680005 IC50 6.0 nM
COc1cc(OC(F)(F)F)cc([C@@H](OC)C(=O)Nc2nnc(N[C@@H]3CCN(c4cccnn4)C3)s2)c1 CHEMBL4476832 IC50 6.0 nM
COc1cc(OC(F)(F)F)cc([C@H](OC)C(=O)Nc2nnc(N[C@@H]3CCN(c4cccnn4)C3)s2)c1 CHEMBL4557531 IC50 6.0 nM
O=C(Cc1ccccn1)Nc1ccc(CCCCn2cc(C(=O)NCc3cccc(OC(F)(F)F)c3)nn2)nn1 CHEMBL4760996 IC50 6.0 nM
O=C1Cc2cccc(c2)OCC/C=C/CCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4849357 IC50 6.0 nM
COc1cccc(C(O)C(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3670016 IC50 7.0 nM
CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1)C(=O)OC(C)(C)C CHEMBL3674976 IC50 7.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 CHEMBL3674998 IC50 7.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)C(O)c4cccc(Cl)c4)nn3)s2)c1 CHEMBL3675007 IC50 7.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCCO)c3)s2)nn1 CHEMBL3675012 IC50 7.0 nM
COCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675013 IC50 7.0 nM
CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675016 IC50 7.0 nM
O=C(CN1CCOCC1)NCc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3675027 IC50 7.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675053 IC50 7.0 nM
CC(C)(O)COc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675065 IC50 7.0 nM
O=C(Cc1cccc(OCCO)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675085 IC50 7.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3ccc(-c4ccccc4)cc3OCCO)s2)nn1 CHEMBL3675087 IC50 7.0 nM
CC(C)(O)Cc1cccc(CC(=O)Nc2nnc(CCCCC(=N)CCC(=N)NC(=O)Cc3ccccc3)s2)c1 CHEMBL3675096 IC50 7.0 nM
COc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F CHEMBL3675098 IC50 7.0 nM
O=C(Cc1ccccc1F)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675103 IC50 7.0 nM
CC(=O)N1CCN(Cc2cc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)ccc2F)CC1 CHEMBL3675107 IC50 7.0 nM
O=C(Cc1ccccc1Cl)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)nn1 CHEMBL3675112 IC50 7.0 nM
Cc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3Cl)nn2)s1 CHEMBL3675114 IC50 7.0 nM
COc1cc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)ccc1F CHEMBL3675116 IC50 7.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(F)c(OCCO)c3)s2)nn1 CHEMBL3675119 IC50 7.0 nM
CCC(O)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675152 IC50 7.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1)c1cccc(C(=O)c2ccccc2)c1 CHEMBL3675163 IC50 7.0 nM
CC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675166 IC50 7.0 nM
CCNC(=O)OC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675170 IC50 7.0 nM
CC(O)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675171 IC50 7.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)CC(O)C(F)(F)F)c3)nn2)s1)c1ccccc1 CHEMBL3675182 IC50 7.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)CC(C)(O)C(F)(F)F)c3)nn2)s1)c1ccccc1 CHEMBL3675183 IC50 7.0 nM
CC(C)(C)OC(=O)N1Cc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2C1 CHEMBL3675184 IC50 7.0 nM
CC(C)(N)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679974 IC50 7.0 nM
CCN(CC)C(=O)COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3679979 IC50 7.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(F)cc3)s2)nn1 CHEMBL3679994 IC50 7.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cc(F)cc(F)c3)s2)nn1 CHEMBL3679995 IC50 7.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(F)c3F)s2)nn1 CHEMBL3679996 IC50 7.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nnc(NC(=O)CC4CCOCC4)s3)C2)s1 CHEMBL4457936 IC50 7.0 nM
CCCCOc1cccc(CC(=O)Nc2ccc(N3CCC(Nc4nnc(NC(=O)CCCC)s4)CC3)nn2)c1 CHEMBL5415225 IC50 7.0 nM
COc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1OC CHEMBL3674982 IC50 8.0 nM
Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3674994 IC50 8.0 nM
O=C(CN1CCOCC1)Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675025 IC50 8.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)nn2)s1)c1ccccc1 CHEMBL3675072 IC50 8.0 nM
CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)nn2)s1 CHEMBL3675074 IC50 8.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccs3)s2)nn1 CHEMBL3675086 IC50 8.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(CO)CO)c3)s2)nn1 CHEMBL3675088 IC50 8.0 nM
O=C(Cc1ccccc1F)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)nn1 CHEMBL3675113 IC50 8.0 nM
COc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1O CHEMBL3675133 IC50 8.0 nM
CCOC(=O)c1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1OCC CHEMBL3675164 IC50 8.0 nM
O=C(Cc1ccccc1OC(F)(F)F)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3679955 IC50 8.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1)c1ccccc1 CHEMBL3679957 IC50 8.0 nM
O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 CHEMBL3679959 IC50 8.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)s1)c1ccccc1 CHEMBL3679977 IC50 8.0 nM
CSc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)s2)c1 CHEMBL3680006 IC50 8.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCC[C@H]2Nc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4437956 IC50 8.0 nM
O=C(Cc1ccccc1)Nc1nnc(NC2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(C(F)(F)F)cc5)nn4)s3)CC2)s1 CHEMBL5185488 IC50 8.66 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3ccc(N4CC[C@@H](Nc5nnc(NC(=O)Cc6ccccn6)s5)C4)nn3)nn2)cc1 CHEMBL5187492 IC50 8.9 nM
O=C(Cc1cccc(Oc2ccccc2)c1)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1 CHEMBL5398770 INH 8.9 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCCCO)c3)s2)nn1 CHEMBL3680035 IC50 9.0 nM
NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3670065 IC50 9.0 nM
Nc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3674995 IC50 9.0 nM
CN(C)CC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3675015 IC50 9.0 nM
CN(C)CC(=O)Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675042 IC50 9.0 nM
CC(C)(O)CNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675097 IC50 9.0 nM
N=C(CCCCc1nnc(NC(=O)Cc2cccc(OCCCO)c2)s1)CCC(=N)NC(=O)Cc1ccccc1 CHEMBL3675102 IC50 9.0 nM
O=C(Cc1cccc(OCCCO)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675118 IC50 9.0 nM
CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1)c1ccc(F)c(CNC(=O)OC(C)(C)C)c1 CHEMBL3675146 IC50 9.0 nM
CC(NC(=O)OC(C)(C)C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(C)c4ccccc4)s3)nn2)c1 CHEMBL3675179 IC50 9.0 nM
CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C(OC)c4ccccc4)s3)nn2)c1 CHEMBL3675185 IC50 9.0 nM
O=C(Cc1ccc(OC(F)(F)F)cc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3679956 IC50 9.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)F)c3)s2)nn1 CHEMBL3680001 IC50 9.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3669995 IC50 10.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cc(F)cc(C(F)(F)F)c3)s2)nn1 CHEMBL3674999 IC50 10.0 nM
O=C(Cc1cccs1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3675082 IC50 10.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC4COC(c5ccccc5)OC4)c3)s2)nn1 CHEMBL3675089 IC50 10.0 nM
COC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)nn2)s1)c1ccccc1 CHEMBL3675092 IC50 10.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(Cl)c(Cl)c3)s2)nn1 CHEMBL3675127 IC50 10.0 nM
CN1CCC(Oc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2)CC1 CHEMBL3675130 IC50 10.0 nM
CC(N)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3675139 IC50 10.0 nM
CC(C(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1)c1ccc(F)c(CN(C)C(=O)OC(C)(C)C)c1 CHEMBL3675175 IC50 10.0 nM
CC(C)(N)c1cccc(CC(=O)Nc2nnc(CCCCC(=N)CCC(=N)NC(=O)Cc3ccccc3)s2)c1 CHEMBL3679973 IC50 10.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cc(F)ccc3F)s2)nn1 CHEMBL3679992 IC50 10.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccncc3)s2)nn1 CHEMBL3680004 IC50 10.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)nn1 CHEMBL3670004 IC50 10.0 nM
C[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1)c1ccccc1 CHEMBL4573635 IC50 10.0 nM
COc1ccc2c(c1)c(CC(=O)Nc1nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)[se]1)cn2C CHEMBL4462204 IC50 10.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC2CCN(c3nnc(NC(=O)C4CC4)s3)CC2)s1 CHEMBL4469854 pIC50 10.0 nM
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(-c4cccc(OC(F)(F)F)c4)ccn3)nn2)nn1 CHEMBL4741606 IC50 10.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(-c4cccc(OC(F)(F)F)c4)ccn3)nn2)nn1 CHEMBL4740054 IC50 10.0 nM
O=C(CCc1cn(Cc2ccc(C(F)(F)F)cc2)nn1)Nc1ccc(N2CC[C@@H](Nc3nnc(NC(=O)Cc4ccccn4)s3)C2)nn1 CHEMBL5194100 IC50 10.25 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(CNC(=O)OC(C)(C)C)c4)s3)s2)c1 CHEMBL3670022 IC50 11.0 nM
CC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3675011 IC50 11.0 nM
NCCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675026 IC50 11.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3c(F)cccc3F)s2)nn1 CHEMBL3675028 IC50 11.0 nM
O=C(Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1)C(O)c1cccc(Cl)c1 CHEMBL3675031 IC50 11.0 nM
O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)C(OC(=O)Cc3cccc(Cl)c3)c3cccc(Cl)c3)s2)nn1 CHEMBL3675034 IC50 11.0 nM
CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)CC(C)C)c3)s2)nn1 CHEMBL3675046 IC50 11.0 nM
CN1CCN(C(=O)c2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2)CC1 CHEMBL3675073 IC50 11.0 nM
COC(C(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)s2)nn1)c1ccccc1 CHEMBL3675091 IC50 11.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(CNC(=O)OC(C)(C)C)c4)s3)nn2)c1 CHEMBL3675149 IC50 11.0 nM
CC(CO)(CO)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675157 IC50 11.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3ccc(N4CC[C@@H](Nc5nnc(NC(=O)Cc6ccccn6)s5)C4)nn3)nn2)cc1 CHEMBL5186321 IC50 11.29 nM
O=C(Cc1ccccc1)Nc1nnc(NC2CCN(c3nnc(NC(=O)c4nccn4Cc4ccc(C(F)(F)F)cc4)s3)CC2)s1 CHEMBL5194638 IC50 11.86 nM
NCc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3674992 IC50 12.0 nM
CC(N)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675138 IC50 12.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CCC(Nc5nnc(NC(=O)Cc6ccccc6)s5)CC4)s3)nn2)cc1 CHEMBL5204137 IC50 12.39 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(C(F)(F)F)cc5)nn4)s3)C2)s1 CHEMBL5207273 IC50 12.4 nM
NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3670038 IC50 13.0 nM
CCNC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)s2)nn1 CHEMBL3675005 IC50 13.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)C(O)(CO)c4ccccc4)nn3)s2)c1 CHEMBL3675090 IC50 13.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(OC(F)(F)F)c4)nn3)s2)c1 CHEMBL3675162 IC50 13.0 nM
COC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)CC(C)(O)C(F)(F)F)c3)nn2)s1)c1ccccc1 CHEMBL3675181 IC50 13.0 nM
CC(N)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)C(C)c3ccccc3)s2)c1 CHEMBL3679960 IC50 13.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc4c3CNC4)s2)nn1 CHEMBL3679983 IC50 13.0 nM
O=C(CCc1cn(Cc2ccc(OC(F)(F)F)cc2)nn1)Nc1ccc(N2CC[C@@H](Nc3nnc(NC(=O)Cc4ccccn4)s3)C2)nn1 CHEMBL5200244 IC50 13.65 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(Cn4cccn4)c3)s2)s1 CHEMBL3674977 IC50 14.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3770355 IC50 14.0 nM
O=C(Cc1ccccc1)Nc1nnc(NC[C@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4473143 IC50 14.0 nM
N#CCNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 CHEMBL4740758 IC50 14.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCn2cc(C(=O)NCc3ccccn3)nn2)nn1 CHEMBL4465413 IC50 14.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCn2cc(C(=O)NCc3ccccc3)nn2)nn1 CHEMBL4742245 IC50 14.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CCC(Nc5nnc(NC(=O)Cc6ccccc6)s5)CC4)s3)nn2)cc1 CHEMBL5172981 IC50 14.73 nM
CC(C)(C)OC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3674985 IC50 15.0 nM
CCNC(=O)OC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(OC(F)(F)F)c4)s3)nn2)c1 CHEMBL3675172 IC50 15.0 nM
COC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)CC(O)C(F)(F)F)c3)nn2)s1)c1ccccc1 CHEMBL3675180 IC50 15.0 nM
CN(C)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3674991 IC50 16.0 nM
CC(C(=O)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1)c1ccccc1 CHEMBL3639739 IC50 16.0 nM
O=C(Cc1ccccc1)Nc1nnc(NCCNc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4461749 IC50 16.0 nM
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)cc(C)n3)nn2)nn1 CHEMBL4741924 IC50 16.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CC[C@@H](Nc5nnc(NC(=O)Cc6ccccc6)s5)C4)s3)nn2)cc1 CHEMBL5208622 IC50 16.61 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(OC(F)(F)F)cc5)nn4)s3)C2)s1 CHEMBL5190676 IC50 16.75 nM
O=C(Cc1ccccc1)Nc1nnc(OC2CCN(c3nnc(NC(=O)C4CCC4)s3)CC2)s1 CHEMBL4436129 pIC50 16.98 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1 CHEMBL4469711 IC50 17.0 nM
CCCCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCCC)s3)nn2)c1 CHEMBL5396169 IC50 17.0 nM
CCCCCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCCC)s3)nn2)c1 CHEMBL5416007 IC50 17.0 nM
O=C(Cc1ccccc1)Nc1nnc(NC2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(OC(F)(F)F)cc5)nn4)s3)CC2)s1 CHEMBL5176889 IC50 17.08 nM
O=C(CCc1cn(Cc2ccc(OC(F)(F)F)cc2)nn1)Nc1ccc(N2CCC(Nc3nnc(NC(=O)Cc4ccccn4)s3)CC2)nn1 CHEMBL5204499 IC50 17.18 nM
O=C(Cc1ccccc1)Nc1nnc(NC2CCN(c3nnc(NC(=O)c4ccn(Cc5ccc(C(F)(F)F)cc5)n4)s3)CC2)s1 CHEMBL5188536 IC50 17.38 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nnc(NC(=O)CCc4cn(-c5ccc(C(F)(F)F)cc5)nn4)s3)C2)s1 CHEMBL5207147 IC50 17.92 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)NC3CCCC3)s2)nn1 CHEMBL3674988 IC50 18.0 nM
CNCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3674993 IC50 18.0 nM
CN(C)CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)s2)nn1 CHEMBL3675061 IC50 18.0 nM
CC(N)c1cc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)ccc1F CHEMBL3679989 IC50 18.0 nM
O=C(CCc1cn(Cc2ccc(C(F)(F)F)cc2)nn1)Nc1ccc(N2CCC(Nc3nnc(NC(=O)Cc4ccccn4)s3)CC2)nn1 CHEMBL5206446 IC50 18.31 nM
CC(C)(C)OC(=O)N1CCN(Cc2cc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)ccc2F)CC1 CHEMBL3675076 IC50 19.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(F)c(CN4CCNCC4)c3)s2)nn1 CHEMBL3675077 IC50 19.0 nM
CC(C(=O)Nc1ccc(CCCCc2nnc(NC(=O)C(C)c3ccccc3)s2)nn1)c1ccccc1 CHEMBL3679954 IC50 19.0 nM
CC(N)c1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F CHEMBL3679988 IC50 19.0 nM
CCCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCCC)s3)nn2)c1 CHEMBL5396294 IC50 19.0 nM
C=CCCOc1cccc(CC(=O)Nc2ccc(N3CCC(Nc4nnc(NC(=O)CCC=C)s4)CC3)nn2)c1 CHEMBL5439210 IC50 19.0 nM
CO[C@H](C(=O)Nc1nnc(NC2CCN(c3nnc(NC(=O)CCc4cn(-c5ccc(C(F)(F)F)cc5)nn4)s3)CC2)s1)c1ccccc1 CHEMBL5178036 IC50 19.26 nM
CO[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1)c1ccccc1 CHEMBL4437106 IC50 20.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cn3cc(F)c(=O)[nH]c3=O)[se]2)nn1 CHEMBL4474779 IC50 20.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3ccc(N4CCC(Nc5nnc(NC(=O)Cc6ccccn6)s5)CC4)nn3)nn2)cc1 CHEMBL5177350 IC50 20.04 nM
Cc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675106 IC50 21.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCC(F)(F)F)c3)s2)nn1 CHEMBL3680002 IC50 21.0 nM
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(C(F)(F)F)cc(C)n3)nn2)nn1 CHEMBL4784091 IC50 21.0 nM
NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)C(O)c4cccc(Cl)c4)nn3)s2)c1 CHEMBL3675008 IC50 22.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)C(C)(C)C)nn3)s2)c1 CHEMBL3675093 IC50 22.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(OC4CCC4)ccn3)nn2)nn1 CHEMBL4797071 IC50 22.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3Cl)s2)nn1 CHEMBL3675105 IC50 23.0 nM
COCCNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 CHEMBL4782339 IC50 23.0 nM
CO[C@H](C(=O)Nc1nnc(NC2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(C(F)(F)F)cc5)nn4)s3)CC2)s1)c1ccccc1 CHEMBL5199798 IC50 23.69 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)s1 CHEMBL3670043 IC50 24.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Nc3ccccc3)s2)nn1 CHEMBL3675004 IC50 24.0 nM
CN(CCN(C)c1nnc(NC(=O)Cc2ccccc2)s1)c1nnc(NC(=O)Cc2ccccc2)s1 CHEMBL4451434 IC50 24.0 nM
CCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCCC)s3)nn2)c1 CHEMBL5419657 IC50 24.0 nM
CCCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C4CC(F)(F)C4)s3)nn2)c1 CHEMBL5399021 IC50 24.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3ccc(N4CCC(Nc5nnc(NC(=O)Cc6ccccn6)s5)CC4)nn3)nn2)cc1 CHEMBL5177442 IC50 24.86 nM
CC(C)Cc1ccc(C(C)C(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 CHEMBL3675136 IC50 25.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 CHEMBL3679993 IC50 25.0 nM
CO[C@H](C(=O)Nc1ccc(N2CC[C@@H](Nc3cccnn3)C2)nn1)c1cccc(OC(F)F)c1 CHEMBL4569564 IC50 25.0 nM
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)ccn3)nn2)nn1 CHEMBL4764721 IC50 25.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL2177757 IC50 25.0 nM
O=C1CCc2cccc(c2)OCCCC/C=C/CCCC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4874803 IC50 25.0 nM
C=CCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCC=C)s3)nn2)c1 CHEMBL5415283 IC50 25.06 nM
CC(C)C(=O)Nc1nnc(N2CCC(Oc3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL4524344 pIC50 26.92 nM
COC(=O)Cc1cccc(OCC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3679969 IC50 27.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccn5)s4)nn3)nn2)cc1 CHEMBL4566446 IC50 27.0 nM
Cn1cc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cn(C)c5ccccc45)[se]3)[se]2)c2ccccc21 CHEMBL4474767 IC50 27.0 nM
CCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCCC)s3)nn2)c1 CHEMBL5416991 IC50 27.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(N)nn3)s2)c1 CHEMBL3674997 IC50 28.0 nM
O=C(O)Cc1cccc(OCC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3679968 IC50 28.0 nM
O=C1Cc2cccc(c2)OCCC/C=C/CCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4862317 IC50 28.0 nM
O=C(/C=C/c1ccc2c(c1)OCO2)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)nn1 CHEMBL5281625 IC50 28.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC2CCN(c3nnc(NC(=O)CC4CC4)s3)CC2)s1 CHEMBL4459383 pIC50 28.84 nM
O=C(Cc1ccccc1)Nc1nnc(NC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL3770617 IC50 29.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL3770889 IC50 30.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC[C@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3770945 IC50 30.0 nM
O=C(Cc1ccccc1)Nc1nnc(NC2CCN(c3nnc(NC(=O)CC4CC4)s3)CC2)s1 CHEMBL3769896 IC50 30.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2ccc(NC(=O)C(O)c3ccccc3)nn2)s1 CHEMBL3670061 IC50 30.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCSc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL4740067 IC50 30.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)s1)C(O)c1cccc(Cl)c1 CHEMBL3670005 IC50 31.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2C[C@H]3C[C@@H]2CN3c2cccnn2)s1 CHEMBL4802038 IC50 31.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)C4(C)COC(C)(C)OC4)nn3)s2)c1 CHEMBL3675108 IC50 32.0 nM
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1 CHEMBL4755823 IC50 32.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 CHEMBL4786715 IC50 32.0 nM
O=C1Cc2cccc(c2)OC/C=C/COc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4858033 IC50 32.0 nM
C=CCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C4CC(F)(F)C4)s3)nn2)c1 CHEMBL5433686 IC50 32.0 nM
C=CCCCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)CCC=C)nn3)s2)c1 CHEMBL5428990 IC50 34.0 nM
COc1cc(-n2c(-c3cccs3)cc(/C=C3\SC(=O)NC3=O)c2-c2cccs2)ccc1-c1ccc(/C=C2\SC(=O)NC2=O)cc1 CHEMBL4082885 IC50 35.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3ccc(N4CC[C@@H](Nc5nnc(NC(=O)Cc6ccccn6)s5)C4)nn3)nn2)cc1OC CHEMBL5178377 IC50 35.72 nM
O=C(Cc1ccccc1)Nc1nnc(O[C@@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3769701 IC50 36.0 nM
O=C(Cc1ccccc1)Nc1ccc(OC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)nn1 CHEMBL3771319 IC50 36.0 nM
C=CCCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)CCC=C)nn3)s2)c1 CHEMBL5394045 IC50 36.0 nM
CCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C4CC4)s3)nn2)c1 CHEMBL5396133 IC50 36.0 nM
O=C1Cc2ccccc2OCCCC/C=C/CCCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4851671 IC50 37.0 nM
CC(C)(C)C(=O)Nc1nnc(OC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL4578823 IC50 38.0 nM
CCc1cc(-c2ccc(-n3c(C)cc(/C=C4\SC(=O)NC4=O)c3C)cc2)ccc1/C=C1\SC(=O)NC1=O CHEMBL4072390 IC50 39.0 nM
O=C(Cc1ccccc1)Nc1nnc(O[C@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3769593 IC50 40.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)s1)C(CO)c1ccccc1 CHEMBL3664925 IC50 40.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(O)c3cccc(Br)c3)s2)s1)C(O)c1cccc(Br)c1 CHEMBL3669988 IC50 40.0 nM
CO[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cc(Cl)cnn3)C2)s1)c1ccccc1 CHEMBL4446717 IC50 40.0 nM
COc1cccc([C@H](OC)C(=O)Nc2nnc(N[C@@H]3CCN(c4ccc(F)nn4)C3)s2)c1 CHEMBL4446548 IC50 40.0 nM
O=C1Cc2cccc(c2)OC/C=C/COc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4868947 IC50 41.0 nM
Cc1cccc(C)c1Cn1cc(CCC(=O)Nc2ccc(N3CC[C@@H](Nc4nnc(NC(=O)Cc5ccccn5)s4)C3)nn2)nn1 CHEMBL5201913 IC50 41.8 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)s1 CHEMBL3680033 IC50 42.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(C(F)(F)F)ccn3)nn2)nn1 CHEMBL4764469 IC50 42.0 nM
COC(C(=O)Cc1cnc(NC2CCN(c3cncnn3)C2)s1)c1cccc(OC(F)(F)F)c1 CHEMBL5268913 IC50 43.0 nM
O=C(CCc1cn(Cc2ccc(C(F)(F)F)cc2)nn1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)nn1 CHEMBL4445509 IC50 44.0 nM
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(C(F)(F)F)ccn3)nn2)nn1 CHEMBL4760268 IC50 44.0 nM
O=C1NC(=O)/C(=C/c2ccc(-c3ccc(-n4c(-c5ccccc5)cc(/C=C5\SC(=O)NC5=O)c4-c4ccccc4)cc3)cc2)S1 CHEMBL4090687 IC50 45.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)ccn3)nn2)nn1 CHEMBL4794180 IC50 46.0 nM
O=C1Cc2cccc(c2)OCC/C=C/CCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4847666 IC50 47.0 nM
CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(C)=O)nn3)s2)c1 CHEMBL3675044 IC50 48.0 nM
COc1cc(-n2c(-c3ccccc3)cc(/C=C3\SC(=O)NC3=O)c2-c2ccccc2)ccc1-c1ccc(/C=C2\SC(=O)NC2=O)cc1 CHEMBL4061000 IC50 48.0 nM
COc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3670049 IC50 49.0 nM
O=C1NC(=O)/C(=C/c2ccc(-c3ccc(-n4c(-c5cccs5)cc(/C=C5\SC(=O)NC5=O)c4-c4cccs4)cc3)cc2)S1 CHEMBL4080388 IC50 49.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(OCC(F)(F)F)ccn3)nn2)nn1 CHEMBL4776071 IC50 49.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@H]2CC[C@H](Nc3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3771020 IC50 50.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)cn1 CHEMBL4562029 IC50 50.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4786465 IC50 50.0 nM
O=C(/C=C/c1ccc2c(c1)OCO2)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)[se]2)nn1 CHEMBL5267355 IC50 50.0 nM
NCc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675051 IC50 51.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3664910 IC50 51.0 nM
Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)c4ccccc4)c3)s2)nn1 CHEMBL3675048 IC50 52.0 nM
CN1CCc2ccccc2[C@H]1C(=O)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1 CHEMBL4528457 IC50 53.0 nM
CCc1cc(-c2ccc(-n3c(-c4cccs4)cc(/C=C4\SC(=O)NC4=O)c3-c3cccs3)cc2)ccc1/C=C1\SC(=O)NC1=O CHEMBL4099331 IC50 54.0 nM
COc1cccc(CNC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3675001 IC50 55.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)C(C)(CO)CO)nn3)s2)c1 CHEMBL3675109 IC50 55.0 nM
Cc1cccc(CNC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3675002 IC50 56.0 nM
O=C(Cc1cccc2[nH]ccc12)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc4[nH]ccc34)s2)s1 CHEMBL3670021 IC50 56.0 nM
CCc1cc(-c2ccc(-n3c(-c4ccccc4)cc(/C=C4\SC(=O)NC4=O)c3-c3ccccc3)cc2)ccc1/C=C1\SC(=O)NC1=O CHEMBL4087349 IC50 56.0 nM
Cc1cc(/C=C2\SC(=O)NC2=O)c(C)n1-c1ccc(-c2ccc(/C=C3\SC(=O)NC3=O)c(Cl)c2)cc1 CHEMBL4074218 IC50 57.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CC[C@@H](Nc5nnc(NC(=O)Cc6ccccc6)s5)C4)s3)nn2)cc1 CHEMBL5202257 IC50 57.0 nM
CCc1cc(-c2ccc(-n3c(C)cc(/C=C4\SC(=O)NC4=O)c3C)cc2C#N)ccc1/C=C1\SC(=O)NC1=O CHEMBL4065595 IC50 59.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC2CN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3769936 IC50 60.0 nM
COc1cccc(C(OC(=O)CCN2CCOCC2)C(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3674989 IC50 60.0 nM
Cn1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccn(C)c4)[se]3)[se]2)c1 CHEMBL4451104 IC50 60.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)[se]2)[se]1 CHEMBL4566474 IC50 60.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3ccc(N4CCC(Nc5nnc(NC(=O)Cc6ccccn6)s5)CC4)nn3)nn2)cc1OC CHEMBL5174131 IC50 60.72 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(Cl)c3)s2)nn1 CHEMBL3670033 IC50 62.0 nM
CNC(=O)c1cn(C[C@@H](F)CCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1 CHEMBL4754753 IC50 62.0 nM
CN1CCN(c2cccc(NC(=O)c3ccc(COCCC4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)cc3)c2)CC1 CHEMBL5399969 IC50 62.0 nM
CC(C)(C)OC(=O)N1Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5cccc(OC(F)(F)F)c5)s4)nn3)c2C1 CHEMBL3675188 IC50 65.0 nM
O=C(Cc1cccc(-n2ccnc2)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(-n4ccnc4)c3)s2)s1 CHEMBL3670060 IC50 65.0 nM
Nc1nnc(N[C@@H]2CCN(c3ccc(NC(=O)Cc4ccccc4)nn3)C2)s1 CHEMBL4448931 IC50 65.0 nM
CN1CCN(c2cccc(NC(=O)c3cccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)c3)c2)CC1 CHEMBL5431067 IC50 65.0 nM
CCc1cc(-c2ccc(-n3c(C)cc(/C=C4\SC(=O)NC4=O)c3C)cc2OC)ccc1/C=C1\SC(=O)NC1=O CHEMBL4065936 IC50 66.0 nM
CN1CCN(c2ccc(C(=O)Nc3ccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)cc3)cc2)CC1 CHEMBL5399803 IC50 66.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccnc3)nn2)nn1 CHEMBL4757740 IC50 67.0 nM
Cc1cccc(C)c1Cn1cc(CCC(=O)Nc2ccc(N3CCC(Nc4nnc(NC(=O)Cc5ccccn5)s4)CC3)nn2)nn1 CHEMBL5177105 IC50 67.85 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccc(O)c(Cl)c3)s2)nn1 CHEMBL3670034 IC50 68.0 nM
C=CCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccc(OCCC=C)c4)s3)nn2)c1 CHEMBL4864113 IC50 68.0 nM
CCCCCCN1CCC(CNC(=O)c2cccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5428029 IC50 68.0 nM
CCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C4CC(F)(F)C4)s3)nn2)c1 CHEMBL5399039 IC50 68.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)NCc3ccccc3)s2)nn1 CHEMBL3670048 IC50 69.0 nM
Cc1cccc(C)c1Cn1cc(CCC(=O)Nc2nnc(N3CCC(Nc4nnc(NC(=O)Cc5ccccc5)s4)CC3)s2)nn1 CHEMBL5207567 IC50 69.12 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3771098 IC50 70.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(O)cc3)s2)s1 CHEMBL3814265 IC50 70.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 CHEMBL3670008 IC50 70.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)s1 CHEMBL3670009 IC50 70.0 nM
NCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3675022 IC50 70.0 nM
CC(=O)Nc1nnc(N2CC[C@@H](Nc3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4472367 IC50 70.0 nM
CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1 CHEMBL4758709 IC50 71.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3OC)s2)s1 CHEMBL3669965 IC50 72.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(O)c3)s2)nn1 CHEMBL3670035 IC50 73.0 nM
COc1ccc2[se]n(CCCCCCn3[se]c4ccc(OCCCCC[C@@H]5SC[C@@H]6NC(=O)N[C@@H]65)cc4c3=O)c(=O)c2c1 CHEMBL4444708 IC50 73.0 nM
COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3670063 IC50 74.0 nM
O=C1CC/C=C/CCC(=O)Nc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)NC(=O)Cc2cccc(c2)N1 CHEMBL4873845 IC50 75.0 nM
O=C1Cc2ccc(cc2)OC/C=C/COc2ccc(cc2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4868178 IC50 76.0 nM
CN1CCN(c2cccc(C(=O)Nc3cccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)c3)c2)CC1 CHEMBL5412671 IC50 77.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CCC(Nc5nnc(NC(=O)Cc6ccccc6)s5)CC4)s3)nn2)cc1OC CHEMBL5192275 IC50 77.5 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)[C@@H](O)c3ccccc3)s2)nn1 CHEMBL3670046 IC50 79.0 nM
CN1CCN(c2cccc(NC(=O)c3ccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)cc3)c2)CC1 CHEMBL5430127 IC50 79.0 nM
C=CCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCC=C)s3)nn2)c1 CHEMBL5428837 IC50 79.0 nM
O=C(Cc1ccccc1)Nc1ccc(SCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL4751180 IC50 80.0 nM
O=C1Cc2ccc(cc2)OCC/C=C/CCOc2ccc(cc2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4872964 IC50 80.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2ccc(NC(=O)NCc3ccccc3)nn2)s1 CHEMBL3674990 IC50 81.0 nM
O=C(Cc1ccccc1Br)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3Br)s2)s1 CHEMBL3669983 IC50 82.0 nM
O=C1Cc2cccc(c2)OCCC/C=C/CCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4849467 IC50 82.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(OC(=O)CCN3CCOCC3)c3cccc(Cl)c3)s2)nn1 CHEMBL3674975 IC50 84.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)OCc3ccccc3)s2)nn1 CHEMBL3674972 IC50 85.0 nM
Cc1ccccc1CN1CCC(CNC(=O)c2cccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5439110 IC50 85.0 nM
O=C(Cc1ccccn1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 CHEMBL3674969 IC50 86.0 nM
C=CCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CCC=C)s3)nn2)c1 CHEMBL5429833 IC50 87.0 nM
CN(C)Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3674979 IC50 88.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCn2cc(C(=O)NCCO)nn2)nn1 CHEMBL4761178 IC50 88.0 nM
CCCCCCN1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5433758 IC50 88.0 nM
CN1CCN(c2ccc(C(=O)Nc3cccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)c3)cc2)CC1 CHEMBL5427647 IC50 89.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2ccc(NC(=O)C(O)c3cccc(Cl)c3)nn2)s1 CHEMBL3670062 IC50 92.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)[C@H](O)c3cccc(Cl)c3)s2)nn1 CHEMBL3680029 IC50 96.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(-n4ccnc4)c3)s2)nn1 CHEMBL3670075 IC50 97.0 nM
O=C(Cc1ccccc1)Nc1ccc(OC2CCN(c3ccc(NC(=O)Cc4ccccc4)nn3)CC2)nn1 CHEMBL3770102 IC50 98.0 nM
CC(=O)N1CCCCC1CC(=O)Nc1nnc(N2CC[C@@H](Nc3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4444363 IC50 99.0 nM
CNCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3674978 IC50 100.0 nM
COc1ccc(OC)c(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 CHEMBL3669972 IC50 100.0 nM
Cc1nccn1Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(Cn5ccnc5C)c4)s3)s2)c1 CHEMBL3669996 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3CO)s2)s1 CHEMBL3670031 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)nn1 CHEMBL3670050 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)nn1 CHEMBL3670051 IC50 100.0 nM
O=C(Cc1ccccn1)Nc1ccc([C@H]2CCN(c3nnc(C(=O)NCc4cc(C(F)(F)F)ccn4)s3)C2)nn1 CHEMBL4455802 IC50 100.0 nM
O=C(Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1)[C@@H](c1cccc(OC(F)(F)F)c1)N1CCC1 CHEMBL4563113 IC50 100.0 nM
O=C(NCc1ccccc1)c1cn(CCCCn2cc(C(=O)NCc3cccc(C(F)(F)F)n3)nn2)nn1 CHEMBL4539656 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1nnc([C@H]2CC[C@H](c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4588102 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1nnc(C[C@H]2C[C@@H]2Cc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4555453 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSc2nnc(NC(=O)Cc3ccccn3)s2)s1 CHEMBL4778536 IC50 100.0 nM
CC(C)NC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 CHEMBL4745830 IC50 100.0 nM
O=C(Cc1ccccc1)Nc1nnc([C@@H]2CCC[C@@H](c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4556013 IC50 100.0 nM
Cc1cc(/C=C2\SC(=O)NC2=O)c(C)n1-c1ccc(-c2ccc(/C=C3\SC(=O)NC3=O)cc2)cc1 CHEMBL4098413 IC50 102.0 nM
CCC(=O)Nc1nnc(N2CCC(Oc3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL4454551 pIC50 102.33 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)NCCNc4ccccc4)cc3)CC2)s1 CHEMBL5401295 IC50 106.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(C(=O)O)cc3)s2)s1 CHEMBL3814401 IC50 110.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)[C@H](O)c3cc(F)cc(F)c3)s2)nn1 CHEMBL3680031 IC50 110.0 nM
COc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(OC)c4)s3)s2)c1 CHEMBL3669870 IC50 110.0 nM
N=C(CCCCc1nnc(NC(=O)Cc2cccc(OCCO)c2)s1)SC(=N)NC(=O)Cc1cccc(OCCO)c1 CHEMBL3669938 IC50 110.0 nM
O=C(Cc1ccccc1Cl)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3Cl)s2)s1 CHEMBL3669957 IC50 110.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cc(F)cc(F)c3)s2)nn1 CHEMBL3670047 IC50 110.0 nM
O=C(Cc1cccc(OCCO)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(OCCO)c3)s2)s1 CHEMBL4560800 IC50 110.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccn5)s4)nn3)nn2)c(C)c1 CHEMBL4461569 IC50 110.0 nM
O=C(Cc1ccccn1)Nc1nnc(CCSc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4759659 IC50 110.0 nM
C=CCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)CC=C)s3)nn2)c1 CHEMBL5412557 IC50 110.0 nM
O=C(NCc1ccccc1)c1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1 CHEMBL4594003 IC50 114.0 nM
CC(C)(O)CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 CHEMBL4788554 IC50 118.0 nM
CC(=O)Oc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccnc4)s3)s2)cc1 CHEMBL3814214 IC50 120.0 nM
O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(O)cc3)s2)s1 CHEMBL3813967 IC50 120.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(O)c3)s2)s1 CHEMBL3814231 IC50 120.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)[C@H](O)c3ccccc3)s2)nn1 CHEMBL3680030 IC50 120.0 nM
O=C(Cc1cccc2[nH]ncc12)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc4[nH]ncc34)s2)s1 CHEMBL3680039 IC50 120.0 nM
COc1cccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cccc(OC)c4)s3)s2)c1 CHEMBL3669867 IC50 120.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3669906 IC50 120.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCSCc2nnc(NC(=O)Cc3ccccc3OC)s2)s1 CHEMBL3669950 IC50 120.0 nM
COc1cccc(CC(=O)Nc2nnc(CCSCc3nnc(NC(=O)Cc4cccc(OC)c4)s3)s2)c1 CHEMBL3669951 IC50 120.0 nM
COc1cccc(C(CO)C(=O)Nc2nnc(CCCCc3nnc(NC(=O)C(CO)c4cccc(OC)c4)s3)s2)c1 CHEMBL3669958 IC50 120.0 nM
O=C(Cc1ccccc1F)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1 CHEMBL3669992 IC50 120.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3ccccc3)s2)nn1 CHEMBL3670014 IC50 120.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(F)c(O)c3F)s2)s1 CHEMBL3670042 IC50 120.0 nM
CC(C)(C)OC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 CHEMBL3670064 IC50 120.0 nM
Cc1nccn1Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3670076 IC50 120.0 nM
CCCCN1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5399908 IC50 120.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCC(CCOCc3ccc(C(=O)NCC4CCN(Cc5cc(F)cc(F)c5)CC4)cc3)CC2)s1 CHEMBL5427092 IC50 120.0 nM
O=C1CCCC/C=C/CCCCOc2cccc(c2)CCC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4867002 IC50 123.0 nM
CN1CCN(c2cccc(C(=O)Nc3ccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)cc3)c2)CC1 CHEMBL5399812 IC50 123.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCC(CCOCc3cccc(C(=O)NCC4CCN(Cc5cc(F)cc(F)c5)CC4)c3)CC2)s1 CHEMBL5402230 IC50 126.0 nM
COc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(OC)cc4)s3)s2)cc1 CHEMBL3669874 IC50 130.0 nM
Cn1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccn(C)c4)s3)s2)c1 CHEMBL4442957 IC50 130.0 nM
CCCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OCCC)c3)nn2)s1 CHEMBL5423461 IC50 130.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)NC4CCCC4)cc3)CC2)s1 CHEMBL5412885 IC50 132.0 nM
Cc1ccccc1CN1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5436285 IC50 135.0 nM
O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 CHEMBL3814899 IC50 140.0 nM
O=C(Cc1cccc2ncccc12)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc4ncccc34)s2)s1 CHEMBL3680040 IC50 140.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)[C@@H](O)c3ccccc3)s2)s1)[C@@H](O)c1ccccc1 CHEMBL3664974 IC50 140.0 nM
CCNC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675003 IC50 140.0 nM
O=C(Cc1cccc(F)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(F)c3)s2)s1 CHEMBL3669974 IC50 140.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)nn1 CHEMBL3670013 IC50 140.0 nM
O=C(Cc1cccc(OC(F)(F)F)c1)Nc1nnc(CCSc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4777997 IC50 140.0 nM
C=CCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OC(=O)CCC=C)c3)nn2)s1 CHEMBL5411562 IC50 140.0 nM
CC(C)CNC(=O)c1ccc(CN2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)cc1 CHEMBL5401042 IC50 146.0 nM
CC(C)(C)OC(=O)N1CCN(Cc2cccc(CC(=O)Nc3nnc(CCSCc4nnc(NC(=O)Cc5cccc(CN6CCN(C(=O)OC(C)(C)C)CC6)c5)s4)s3)c2)CC1 CHEMBL3669976 IC50 150.0 nM
COc1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(OC)cc4)s3)s2)cc1 CHEMBL3669872 IC50 150.0 nM
COc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(OC)c4OC)s3)s2)c1OC CHEMBL3669961 IC50 150.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCc4ccccc4)c3)s2)nn1 CHEMBL3670036 IC50 150.0 nM
CO[C@@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1)c1ccccc1 CHEMBL4573807 IC50 150.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccn5)s4)nn3)nn2)cc1 CHEMBL4554275 IC50 150.0 nM
O=C(CC1CC1)Nc1nnc(OC2CCN(c3nnc(NC(=O)CC4CC4)s3)CC2)s1 CHEMBL3769897 IC50 157.0 nM
COc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(OC)c(OC)c4)s3)s2)cc1OC CHEMBL3669871 IC50 160.0 nM
CCOc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3OCC)s2)s1 CHEMBL3670000 IC50 160.0 nM
COc1ccc(Cl)c(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1F CHEMBL3670040 IC50 160.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3c(Cl)ccc(O)c3F)s2)s1 CHEMBL3670041 IC50 160.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3cccc(Cl)c3)s2)s1 CHEMBL3670068 IC50 160.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)nn1 CHEMBL3670077 IC50 160.0 nM
CCCCN1CCC(CNC(=O)c2cccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5427312 IC50 160.0 nM
CCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)C4CC4)s3)nn2)c1 CHEMBL5414772 IC50 160.0 nM
O=C(CC1CC1)Nc1nnc(N2CCC(Oc3nnc(NC(=O)C4CCC4)s3)CC2)s1 CHEMBL4588969 IC50 162.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)NCCN4CCCCC4)cc3)CC2)s1 CHEMBL5426166 IC50 162.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)NCCN4CCCC4)cc3)CC2)s1 CHEMBL5396735 IC50 163.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(Br)cn3)s2)s1 CHEMBL3814007 IC50 170.0 nM
O=C(Cc1cccc2cnccc12)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc4cnccc34)s2)s1 CHEMBL3680038 IC50 170.0 nM
NCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(CN)c4)s3)s2)c1 CHEMBL3670023 IC50 170.0 nM
O=C(Cc1ccccc1CO)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3CO)s2)s1 CHEMBL3669915 IC50 170.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3OC)s2)s1 CHEMBL3669926 IC50 170.0 nM
Nc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(N)c4)s3)s2)c1 CHEMBL3670027 IC50 170.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3ccccn3)s2)s1 CHEMBL3670069 IC50 170.0 nM
CCCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(O)c3)nn2)s1 CHEMBL5417938 IC50 170.0 nM
CO[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3nccnn3)C2)s1)c1ccc(F)cc1 CHEMBL3808882 IC50 175.1 nM
O=C(Cc1cccs1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccs3)s2)s1 CHEMBL3664970 IC50 180.0 nM
NS(=O)(=O)c1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(S(N)(=O)=O)cc4)s3)s2)cc1 CHEMBL3669905 IC50 180.0 nM
COc1cc(CC(=O)NC(=N)SC(=N)CCSCCc2nnc(NC(=O)Cc3cc(OC)cc(OC)c3)s2)cc(OC)c1 CHEMBL3669909 IC50 180.0 nM
CN(C)[C@H](C(=O)Nc1nnc(N[C@@H]2CCN(c3cccnn3)C2)s1)c1cccc(OC(F)(F)F)c1 CHEMBL4446391 IC50 180.0 nM
O=C1Cc2cccc(c2)OCCOc2cccc(c2)CC(=O)Nc2ccc(nn2)CCCCc2ccc(nn2)N1 CHEMBL5277719 IC50 180.0 nM
O=C1Cc2cccc(c2)OCCCOc2cccc(c2)CC(=O)Nc2ccc(nn2)CCCCc2cnnc(c2)N1 CHEMBL5288019 IC50 180.0 nM
O=C(Cc1ccccc1)Nc1nnc(OCC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL3770229 IC50 190.0 nM
Nc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(N)cc4)s3)s2)cc1 CHEMBL3669904 IC50 190.0 nM
Cc1cccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cccc(C)c4)s3)s2)c1 CHEMBL3669948 IC50 190.0 nM
COc1cccc(C(CO)C(=O)Nc2nnc(CCSCc3nnc(NC(=O)C(CO)c4cccc(OC)c4)s3)s2)c1 CHEMBL3669959 IC50 190.0 nM
O=C(Cc1cccc(-n2cccn2)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(-n4cccn4)c3)s2)s1 CHEMBL3669986 IC50 190.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)s1 CHEMBL3670015 IC50 190.0 nM
CCCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OC)c3)nn2)s1 CHEMBL5437177 IC50 190.0 nM
O=C1Cc2ccc(cc2)OCCCC/C=C/CCCCOc2ccc(cc2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4868584 IC50 193.0 nM
CC(C)C(=O)Nc1nnc(N2CCC(Oc3nnc(NC(=O)CC4CC4)s3)CC2)s1 CHEMBL4454980 pIC50 199.53 nM
O=C(Cc1ccsc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccsc3)s2)s1 CHEMBL3664971 IC50 200.0 nM
O=C(Cc1cccc(OCCO)c1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccc(OCCO)c3)s2)s1 CHEMBL3669939 IC50 200.0 nM
O=C(Cc1cccs1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3cccs3)s2)s1 CHEMBL3669940 IC50 200.0 nM
O=C(Cc1ccccc1F)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1 CHEMBL3669994 IC50 200.0 nM
O=C(Cc1cccnc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 CHEMBL3670010 IC50 200.0 nM
COc1ccc([C@@H](C(=O)Nc2nnc(N[C@@H]3CCN(c4cccnn4)C3)s2)N(C)C)cc1 CHEMBL4445730 IC50 200.0 nM
CN(C)c1ccc(CC(=O)Nc2nnc(CCSc3nnc(NC(=O)Cc4ccccc4)s3)s2)cc1 CHEMBL4783740 IC50 200.0 nM
O=c1c2ccccc2[se]n1CCCCCCn1[se]c2ccccc2c1=O CHEMBL2035464 IC50 200.0 nM
Cc1nn(CC[Se][Se]CCn2nc(C)c3ccccc32)c2ccccc12 CHEMBL5395264 IC50 200.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3664957 IC50 202.0 nM
Nc1nnc(N2CCC(Oc3nnc(NC(=O)Cc4ccccc4)s3)CC2)s1 CHEMBL3769551 IC50 207.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nccnn3)C2)s1 CHEMBL4447951 IC50 207.0 nM
COc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)cc1 CHEMBL3813769 IC50 210.0 nM
CCCCOC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3674974 IC50 210.0 nM
Cc1ccc(NC(=O)c2ccc(CN3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)cc1 CHEMBL5429509 IC50 212.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3cccc(C(=O)NCCN4CCCCC4)c3)CC2)s1 CHEMBL5422733 IC50 212.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@H]2CCN(c3nnc(NC(=O)CCc4cn(-c5ccc(C(F)(F)F)cc5)nn4)s3)C2)s1 CHEMBL5196439 IC50 215.93 nM
Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 CHEMBL3674996 IC50 220.0 nM
Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 CHEMBL3675160 IC50 220.0 nM
CS(=O)(=O)c1cccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cccc(S(C)(=O)=O)c4)s3)s2)c1 CHEMBL3669869 IC50 220.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 CHEMBL3670044 IC50 220.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)s1 CHEMBL3670074 IC50 220.0 nM
CCCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OCC)c3)nn2)s1 CHEMBL5436876 IC50 220.0 nM
CCNCCNC(=O)c1ccc(CN2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)cc1 CHEMBL5436092 IC50 221.0 nM
O=C1Cc2cccc(c2)OCCCC/C=C/CCCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL4873841 IC50 225.0 nM
Nc1nnc(N2CC(Nc3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3769973 IC50 227.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@H]2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(C(F)(F)F)cc5)nn4)s3)C2)s1 CHEMBL5169461 IC50 227.03 nM
O=C(Cc1ccsc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccsc3)s2)s1 CHEMBL3664967 IC50 230.0 nM
CN(C)c1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(N(C)C)cc4)s3)s2)cc1 CHEMBL3669873 IC50 230.0 nM
COc1cccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cccc(OC)c4OC)s3)s2)c1OC CHEMBL3669960 IC50 230.0 nM
CC(C)C(=O)Nc1nnc(N2CCC(Oc3nnc(NC(=O)C4CCC4)s3)CC2)s1 CHEMBL4441341 pIC50 239.88 nM
Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)s1 CHEMBL3679990 IC50 240.0 nM
O=C(Cc1cccc(F)c1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccc(F)c3)s2)s1 CHEMBL3664984 IC50 240.0 nM
O=C(Cc1cccs1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccs3)s2)s1 CHEMBL3664998 IC50 240.0 nM
CN(C)c1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(N(C)C)cc4)s3)s2)cc1 CHEMBL3669875 IC50 240.0 nM
NS(=O)(=O)c1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(S(N)(=O)=O)cc4)s3)s2)cc1 CHEMBL3669924 IC50 240.0 nM
O=C(Cc1c(F)cccc1F)Nc1nnc(CCCCc2nnc(NC(=O)Cc3c(F)cccc3F)s2)s1 CHEMBL3669993 IC50 240.0 nM
CNc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(NC)cc4)s3)s2)cc1 CHEMBL4436330 IC50 240.0 nM
C=CCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)CCC=C)nn3)s2)c1 CHEMBL5411575 IC50 240.0 nM
COc1cc(-n2c(C)cc(/C=C3\SC(=O)NC3=O)c2C)ccc1-c1ccc(/C=C2\SC(=O)NC2=O)cc1 CHEMBL4069677 IC50 243.0 nM
CN1CCC(CC(=O)Nc2nnc(N3CC[C@@H](Nc4nnc(NC(=O)Cc5ccccc5)s4)C3)s2)CC1 CHEMBL4548654 IC50 244.0 nM
Cc1cc(/C=C2\SC(=O)NC2=O)c(C)n1-c1ccc(-c2ccc(/C=C3\SC(=O)NC3=O)cc2)c(O)c1 CHEMBL4087025 IC50 247.0 nM
CCCC(=O)OC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1)c1cccc(Cl)c1 CHEMBL3675024 IC50 250.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(CO)c3cccs3)s2)s1)C(CO)c1cccs1 CHEMBL3669898 IC50 250.0 nM
CN1CCN(c2ccc(NC(=O)c3ccc(CN4CCN(c5nnc(NC(=O)Cc6ccccc6)s5)CC4)cc3)cc2)CC1 CHEMBL5437334 IC50 250.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)NCc4cccc(C(F)(F)F)c4)cc3)CC2)s1 CHEMBL5431922 IC50 253.0 nM
O=C(Cc1ccc2ncccc2c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc4ncccc4c3)s2)s1 CHEMBL3669970 IC50 260.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)OCc3ccccc3)s2)s1 CHEMBL3670070 IC50 260.0 nM
Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCc4ccccc4)c3)s2)nn1 CHEMBL3674971 IC50 260.0 nM
CCCN1CCC(CNC(=O)c2cccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5407314 IC50 260.0 nM
CCN(CC)CCNC(=O)c1ccc(CN2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)cc1 CHEMBL5439818 IC50 264.0 nM
C=CCCC(=O)N1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5435169 IC50 268.0 nM
N#Cc1cccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cccc(C#N)c4)s3)s2)c1 CHEMBL3669866 IC50 270.0 nM
COc1ccc(OC)c(CC(=O)Nc2nnc(CCCc3nnc(NC(=O)Cc4cc(OC)ccc4OC)s3)s2)c1 CHEMBL3669966 IC50 270.0 nM
O=C(O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(CC(=O)O)c4)s3)s2)c1 CHEMBL3670012 IC50 270.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C3CC(O)c4ccccc43)s2)s1)C1CC(O)c2ccccc21 CHEMBL3664976 IC50 280.0 nM
COc1cccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccccn4)s3)s2)c1 CHEMBL3670056 IC50 280.0 nM
CC(C)COC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3670066 IC50 280.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)[C@@H](O)c3ccccc3)s2)s1 CHEMBL3670073 IC50 280.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3nnc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)s3)nn2)c(C)c1 CHEMBL4526354 IC50 280.0 nM
Cn1cc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4cn(C)c5ccccc45)s3)s2)c2ccccc21 CHEMBL3669907 IC50 280.0 nM
O=C(Cc1ccccc1)Nc1nnc([C@H]2CCC[C@H](c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4466771 IC50 280.0 nM
C=CCCCCOc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(N)s3)nn2)c1 CHEMBL5411945 IC50 280.0 nM
CCNC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CN)c3)s2)nn1 CHEMBL3675006 IC50 290.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(O)c3ccccc3)s2)s1)C(O)c1ccccc1 CHEMBL3669884 IC50 290.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)C(O)(CO)c3ccccc3)s2)s1 CHEMBL3669981 IC50 290.0 nM
CCCN1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5426671 IC50 290.0 nM
C#CCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OCCC=C)c3)nn2)s1 CHEMBL5415915 IC50 290.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C3COc4ccccc43)s2)s1)C1COc2ccccc21 CHEMBL3665014 IC50 300.0 nM
Nc1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(N)cc4)s3)s2)cc1 CHEMBL3669903 IC50 300.0 nM
N=C(CCSCC(=N)SC(=N)NC(=O)C(CO)c1ccccc1)SC(=N)NC(=O)C(CO)c1ccccc1 CHEMBL3669942 IC50 300.0 nM
O=C(CCc1cn(Cc2ccc(OC(F)(F)F)cc2)nn1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)nn1 CHEMBL4461687 IC50 300.0 nM
Nc1nnc(CCSCCc2nnc(NC(=O)CC34CC5CC(CC(C5)C3)C4)[se]2)[se]1 CHEMBL4590724 IC50 300.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)NCCc4ccc(F)cc4)cc3)CC2)s1 CHEMBL5417574 IC50 300.0 nM
O=C1Cc2cccc(c2)OCCCOCCCOc2cccc(c2)CC(=O)Nc2ccc(nn2)CCCCc2ccc(nn2)N1 CHEMBL5271248 IC50 310.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CC[C@H](Nc5nnc(NC(=O)Cc6ccccc6)s5)C4)s3)nn2)cc1 CHEMBL5170548 IC50 312.3 nM
CCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 CHEMBL3675071 IC50 320.0 nM
O=C(Cc1ccco1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccco3)s2)s1 CHEMBL3664969 IC50 320.0 nM
COc1ccccc1C(C)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(C)c3ccccc3OC)s2)s1 CHEMBL3669964 IC50 320.0 nM
Cc1cccc(C)c1Cn1cc(CCC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccn4)s3)nn2)nn1 CHEMBL4527166 IC50 320.0 nM
CN1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5439476 IC50 320.0 nM
O=C(Cc1ccccc1CO)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3CO)s2)s1 CHEMBL3669891 IC50 330.0 nM
CCOc1ccccc1CC(=O)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3OCC)s2)s1 CHEMBL3669999 IC50 330.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccn5)s4)nn3)nn2)cc1OC CHEMBL4447580 IC50 330.0 nM
COc1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(OC)c(OC)c4)s3)s2)cc1OC CHEMBL3669868 IC50 340.0 nM
CCN(CC)CCNC(=O)c1cccc(CN2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)c1 CHEMBL5397823 IC50 345.0 nM
Nc1nnc(N2CC[C@@H](Nc3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL4438255 IC50 347.0 nM
O=C(Cc1cccc(Cn2cccn2)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(Cn4cccn4)c3)s2)s1 CHEMBL3670059 IC50 350.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)s1 CHEMBL3670072 IC50 350.0 nM
C=CCCC(=O)N1CCC(CNC(=O)c2cccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5409517 IC50 350.0 nM
N=C(CCSCC(=N)SC(=N)NC(=O)[C@@H](O)c1ccccc1)SC(=N)NC(=O)[C@@H](O)c1ccccc1 CHEMBL3669945 IC50 360.0 nM
Cc1ccccc1C(C)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(C)c3ccccc3C)s2)s1 CHEMBL3669963 IC50 360.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCN(Cc3ccc(C(=O)N4CCC(CO)CC4)cc3)CC2)s1 CHEMBL5405323 IC50 363.0 nM
CC(C)N1CCC(CNC(=O)c2ccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)cc2)CC1 CHEMBL5398509 IC50 365.0 nM
O=C1CCc2cccc(c2)OCC/C=C/CCCC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL4875193 IC50 372.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(Oc4ccccc4)cc3)s2)s1 CHEMBL3813734 IC50 380.0 nM
COc1cc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cc(OC)cc(OC)c4)s3)s2)cc(OC)c1 CHEMBL3669912 IC50 380.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)[C@@H](O)c3ccccc3Cl)s2)s1)[C@@H](O)c1ccccc1Cl CHEMBL3669917 IC50 380.0 nM
N=C(CCCCc1nnc(NC(=O)Cc2cccc(OCCN3CCOCC3)c2)s1)SC(=N)NC(=O)Cc1cccc(OCCN2CCOCC2)c1 CHEMBL3669944 IC50 380.0 nM
O=C(Cc1ccccc1Cl)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3Cl)s2)s1 CHEMBL3669956 IC50 380.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(O)(CO)c3ccccc3)s2)s1)C(O)(CO)c1ccccc1 CHEMBL3669979 IC50 380.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccn3)s2)s1 CHEMBL3670055 IC50 380.0 nM
O=C(Cc1cccc(OCCN2CCOCC2)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)s1 CHEMBL4473578 IC50 380.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3664901 IC50 380.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@H]2CCN(c3nnc(NC(=O)CCc4cn(Cc5ccc(OC(F)(F)F)cc5)nn4)s3)C2)s1 CHEMBL5183225 IC50 381.48 nM
O=C(Nc1nnc(CCSCCc2nnc(NC(=O)c3cccs3)s2)s1)c1cccs1 CHEMBL4456690 IC50 390.0 nM
C#CCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(OC(=O)CCC#C)c3)nn2)s1 CHEMBL5409568 IC50 390.0 nM
COc1ccccc1CC(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(CO)c3ccccc3OC)s2)s1 CHEMBL3669947 IC50 400.0 nM
COc1ccc(C(O)C(=O)Nc2nnc(CCCCc3nnc(NC(=O)C(O)c4ccc(OC)cc4)s3)s2)cc1 CHEMBL3670019 IC50 400.0 nM
O=C1Cc2cccc(c2)OCCOCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL5288599 IC50 400.0 nM
O=[N+]([O-])c1ccc2c(cnn2CC[Se][Se]CCn2ncc3cc([N+](=O)[O-])ccc32)c1 CHEMBL5397149 IC50 400.0 nM
O=C1c2ccccc2C(=O)N1CC[Se][Se]CCN1C(=O)c2ccccc2C1=O CHEMBL5440854 IC50 400.0 nM
O=C1Cc2cccc(c2)OCC/C=C/CCCC(=O)Nc2nnc(s2)CCCCc2nnc(s2)C1 CHEMBL4869707 IC50 410.0 nM
Cc1ccc(Cn2cc(CCC(=O)Nc3nnc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)s3)nn2)cc1 CHEMBL4456304 IC50 420.0 nM
CCCNC(=O)c1ccc(COCCC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)cc1 CHEMBL5420513 IC50 420.0 nM
CCCC(=O)OCN(C(=O)C(CO)c1cccc(CNC(=O)OC(C)(C)C)c1)c1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675145 IC50 430.0 nM
CCCC(=O)OCN(C(=O)Cc1cccc(CC(=O)N2CCC(F)(F)CC2)c1)c1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 CHEMBL3675148 IC50 430.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)[C@@H](O)Cc3ccccc3)s2)s1)[C@@H](O)Cc1ccccc1 CHEMBL3669860 IC50 430.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Oc3ccccc3)s2)s1 CHEMBL3670067 IC50 430.0 nM
O=C1Cc2cccc(c2)OCCOCCOc2cccc(c2)CC(=O)Nc2ccc(nn2)CCCCc2ccc(nn2)N1 CHEMBL5270634 IC50 430.0 nM
CN1CCC(CNC(=O)c2cccc(CN3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5415662 IC50 432.0 nM
CCN(CC)CCNC(=O)c1ccc(COCCC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)cc1 CHEMBL5438137 IC50 440.0 nM
CC(C)(C)OC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)cc1 CHEMBL3815103 IC50 450.0 nM
O=C(CCCC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)nn1)NCCNC(=S)Nc1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21 CHEMBL4593229 Kd 450.0 nM
COc1ccc(C(=O)Nc2nnc(CCSCCc3nnc(NC(=O)c4ccc(OC)cc4)s3)s2)cc1 CHEMBL3664893 IC50 460.0 nM
O=C(Cc1cccnc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 CHEMBL3680037 IC50 480.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCC(CCOCc3cccc(C(=O)NCCN4CCCC4)c3)CC2)s1 CHEMBL5431271 IC50 489.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC2CCCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3770357 IC50 490.0 nM
O=C(Cc1ccccn1)Nc1nnc([C@@H]2CC[C@H](c3nnc(NC(=O)Cc4ccccn4)s3)C2)s1 CHEMBL4578477 IC50 500.0 nM
O=C(Cc1ccccn1)Nc1nnc(C[C@@H]2C[C@H]2Cc2nnc(NC(=O)Cc3ccccn3)s2)s1 CHEMBL4532984 IC50 500.0 nM
O=C(Cc1ccccn1)Nc1nnc(C[C@H]2CC[C@H](Cc3nnc(NC(=O)Cc4ccccn4)s3)CC2)s1 CHEMBL4454895 IC50 500.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3nnc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)s3)nn2)cc1OC CHEMBL4435743 IC50 500.0 nM
O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)s1 CHEMBL3813810 IC50 510.0 nM
O=C(Nc1nnc(CCSCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)s1)C(CO)c1ccccc1 CHEMBL3664913 IC50 510.0 nM
CC(C)(C)OC(=O)N1CCCC(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)CC4CCCN(C(=O)OC(C)(C)C)C4)s3)s2)C1 CHEMBL3664994 IC50 510.0 nM
O=C(Nc1nnc(CCSCCc2nnc(NC(=O)C3COc4ccccc43)s2)s1)C1COc2ccccc21 CHEMBL3665012 IC50 510.0 nM
COCC(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(COC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3669876 IC50 510.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3nnc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)s3)nn2)cc1 CHEMBL4436657 IC50 510.0 nM
COc1ccccc1C(CO)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(CO)c3ccccc3OC)s2)s1 CHEMBL3669946 IC50 520.0 nM
Cc1cccc(C)c1Cn1cc(CCC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)nn1 CHEMBL4450088 IC50 520.0 nM
CCCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(N)c3)nn2)s1 CHEMBL5422173 IC50 520.0 nM
CCCCNC(=O)c1ccc(COCC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)cc1 CHEMBL5414948 IC50 530.0 nM
C=CCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(O)c3)nn2)s1 CHEMBL5396896 IC50 530.0 nM
Nc1nnc(N2CC(Oc3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3770218 IC50 540.0 nM
CC(=O)Oc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)cc1 CHEMBL3814398 IC50 540.0 nM
O=C(Cc1cccc(OCCN2CCOCC2)c1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)s1 CHEMBL3669943 IC50 540.0 nM
O=C(Cc1cccc(CN2CCNCC2)c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(CN4CCNCC4)c3)s2)s1 CHEMBL3669977 IC50 540.0 nM
Cc1nn(CC[Se][Se]CCn2nc(C)c(Cl)c2C)c(C)c1Cl CHEMBL5416840 IC50 540.0 nM
COc1ccc(Cn2cc(CCC(=O)Nc3nnc(N4CC[C@H](Nc5nnc(NC(=O)Cc6ccccc6)s5)C4)s3)nn2)cc1 CHEMBL5174974 IC50 544.11 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCC(CCOCc3cccc(C(=O)N4CCN(c5cccc(F)c5)CC4)c3)CC2)s1 CHEMBL5414977 IC50 546.0 nM
O=C(Cc1ccccc1)Nc1nnc(N2CCC(CCOCc3cccc(C(=O)NCCN4CCCCC4)c3)CC2)s1 CHEMBL5431644 IC50 555.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)s1 CHEMBL3664918 IC50 560.0 nM
Cc1cc(C)n(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cn4nc(C)cc4C)s3)s2)n1 CHEMBL3664979 IC50 560.0 nM
CCC(O)(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(O)(CC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3680017 IC50 570.0 nM
O=C(Nc1nnc(CCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)s1)C(CO)c1ccccc1 CHEMBL3669886 IC50 570.0 nM
O=C(CCN1CCOCC1)OCC(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(CO)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3669931 IC50 570.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(O)c3ccccc3Br)s2)s1)C(O)c1ccccc1Br CHEMBL3669987 IC50 570.0 nM
CC[C@](O)(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)[C@@](O)(CC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL4454485 IC50 570.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)CC3=CN4CCCN=C4S3)s2)nn1 CHEMBL3675094 IC50 580.0 nM
CS(=O)(=O)c1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(S(C)(=O)=O)cc4)s3)s2)cc1 CHEMBL3669892 IC50 580.0 nM
C#CCCC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(O)c3)nn2)s1 CHEMBL5427008 IC50 580.0 nM
CO[C@H](C(=O)Nc1nnc(CCCCc2nnc(NC(=O)[C@@H](OC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3669861 IC50 590.0 nM
O=C(NCc1ccccc1)c1nnc(N[C@@H]2CCN(c3nccnn3)C2)s1 CHEMBL4534437 IC50 590.0 nM
CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)CC4CCN(C(=O)OC(C)(C)C)CC4)s3)s2)CC1 CHEMBL3664996 IC50 600.0 nM
O=C(Cc1ccc2ncccc2c1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccc4ncccc4c3)s2)s1 CHEMBL3669969 IC50 600.0 nM
O=C(Cc1ccccn1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccn3)s2)s1 CHEMBL3670007 IC50 600.0 nM
O=C(Cc1cccc(OCCN2CCOCC2)c1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)s1 CHEMBL3669968 IC50 610.0 nM
CO[C@H](C(=O)Nc1nnc(CCCCc2nnc(NC(=O)[C@H](OC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3680018 IC50 620.0 nM
CC(C)(C)OC(=O)N1CCCC(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)CC4CCCN(C(=O)OC(C)(C)C)C4)s3)s2)C1 CHEMBL3664997 IC50 620.0 nM
CO[C@@H](C(=O)Nc1nnc(CCCCc2nnc(NC(=O)[C@H](OC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL4456954 IC50 620.0 nM
CCN(CC)CCNC(=O)c1cccc(COCCC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)c1 CHEMBL5407097 IC50 621.0 nM
COc1cc(C(O)C(=O)Nc2nnc(CCCCc3nnc(NC(=O)C(O)c4ccc(O)c(OC)c4)s3)s2)ccc1O CHEMBL3670018 IC50 640.0 nM
O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)C(OC(=O)CCN3CCOCC3)c3ccccc3)s2)nn1 CHEMBL3670032 IC50 640.0 nM
O=C(Cc1ccccc1Br)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3Br)s2)s1 CHEMBL3669984 IC50 660.0 nM
CC1(C)OCC(C(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)(c2ccccc2)O1 CHEMBL3669980 IC50 680.0 nM
O=C(Nc1nnc(CCCCc2nnc(NC(=O)C(O)Cc3ccccc3)s2)s1)C(O)Cc1ccccc1 CHEMBL3639638 IC50 690.0 nM
CC(C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(C)c3ccccc3Cl)s2)s1)c1ccccc1Cl CHEMBL3669962 IC50 700.0 nM
O=C(C[C@@H](O)Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)C[C@@H](O)Cc3ccccc3)s2)s1 CHEMBL3680021 IC50 710.0 nM
CC(=O)Nc1nnc(N[C@@H]2CCN(c3nnc(NC(C)=O)s3)C2)s1 CHEMBL3769558 IC50 720.0 nM
CC(CO)(CO)C(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc(F)c3)s2)s1 CHEMBL3669865 IC50 730.0 nM
O=C(Cc1c(F)cccc1F)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3c(F)cccc3F)s2)s1 CHEMBL3669998 IC50 730.0 nM
CC(C)NC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3675023 IC50 740.0 nM
C=C(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(COC(=O)CCN3CCOCC3)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3669982 IC50 740.0 nM
O=C(CCc1ccccc1)N[C@H](CO)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)[C@@H](CO)NC(=O)CCc3ccccc3)s2)s1 CHEMBL3680015 IC50 750.0 nM
O=C(CCc1ccccc1)N[C@@H](CO)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)[C@H](CO)NC(=O)OCc3ccccc3)s2)s1 CHEMBL3669856 IC50 750.0 nM
CC(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(C)c3ccccc3Cl)s2)s1)c1ccccc1Cl CHEMBL3669975 IC50 750.0 nM
O=C1NC(=O)/C(=C/c2cc(-c3cccs3)n(-c3ccc(Br)cc3)c2-c2cccs2)S1 CHEMBL4100814 IC50 754.0 nM
O=C(Cc1ccccc1)Nc1nnc(OC[C@@H]2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 CHEMBL3770066 IC50 790.0 nM
O=C(Cc1ccco1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccco3)s2)s1 CHEMBL3664965 IC50 800.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)[C@H]3CCCC[C@@H]3C(=O)c3ccccc3)s2)s1 CHEMBL3669990 IC50 800.0 nM
O=C1Cc2cccc(c2)OCCCOCCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2ccc(nn2)N1 CHEMBL5266308 IC50 800.0 nM
CN1CCC(CNC(=O)c2cccc(COCCC3CCN(c4nnc(NC(=O)Cc5ccccc5)s4)CC3)c2)CC1 CHEMBL5412204 IC50 802.0 nM
CCOC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL3680032 IC50 810.0 nM
NCCC(C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(CN)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3669921 IC50 820.0 nM
O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)C(c3ccccc3)N3CCNCC3)s2)s1 CHEMBL3664963 IC50 840.0 nM
N#Cc1ccc(Cn2cc(CCC(=O)Nc3nnc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)s3)nn2)cc1 CHEMBL4589700 IC50 840.0 nM
O=C(Cc1ccccc1)Nc1nnc(N[C@@H]2CCN(c3nncs3)C2)s1 CHEMBL4570299 IC50 873.0 nM
N#Cc1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(C#N)cc4)s3)s2)cc1 CHEMBL3669923 IC50 890.0 nM
O=C(Nc1nnc(CCSCCc2nnc(NC(=O)[C@@H](O)c3ccccc3)s2)s1)[C@@H](O)c1ccccc1 CHEMBL3664975 IC50 900.0 nM
O=C(CCc1cn(Cc2ccccc2)nn1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4566122 IC50 900.0 nM
COCC(C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(COC)c3ccccc3)s2)s1)c1ccccc1 CHEMBL3669911 IC50 920.0 nM
CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)CC4CCN(C(=O)OC(C)(C)C)CC4)s3)s2)CC1 CHEMBL3664993 IC50 950.0 nM
O=C(CCc1cn(Cc2ccc(Br)cc2)nn1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 CHEMBL4474044 IC50 980.0 nM
O=C1Cc2cccc(c2)OCCOc2cccc(c2)CC(=O)Nc2nnc(s2)CCCCc2nnc(s2)N1 CHEMBL5275641 IC50 980.0 nM