O=C(O)c1cc2c3ccccc3c3cc(C(=O)O)c(=O)oc3c2oc1=O CHEMBL4857772 EC50 0.31 nM
COc1cc(F)c(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)c(F)c1 CHEMBL2425821 Ki 0.589 nM
CCCOc1ccccc1-c1nc2[nH]nnc2c(=O)[nH]1 CHEMBL28079 EC50 0.71 nM
Cc1c2[nH]c(C(=O)O)cc(=O)c2cc2c(=O)cc(C(=O)O)[nH]c12 CHEMBL3306990 IC50 0.74 nM
O=C(O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1 CHEMBL2392171 Ki 0.938 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)c(Cl)c1 CHEMBL2392179 Ki 1.12 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)c(F)c1 CHEMBL2425819 Ki 1.37 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1F CHEMBL2425820 Ki 1.64 nM
COc1ccc(C(=O)Nc2cc(Cl)cc3c(=O)cc(C(=O)O)oc23)c(F)c1 CHEMBL2425824 Ki 1.92 nM
O=C(O)c1cc2ccccc2c(Cc2c(O)c(C(=O)O)cc3ccccc23)c1O CHEMBL177880 EC50 2.0 nM
COc1ccc(-c2c3oc(=O)c(C(=O)O)cc3cc3cc(C(=O)O)c(=O)oc23)cc1 CHEMBL4870213 IC50 2.0 nM
O=C(Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12)c1ccc(Cl)c(Cl)c1 CHEMBL2392172 Ki 2.18 nM
COc1ccc(-c2cc3cc(C(=O)O)c(=O)oc3c3cc(C(=O)O)c(=O)oc23)cc1 CHEMBL4856506 IC50 2.45 nM
COc1cccc(-c2cc3cc(C(=O)O)c(=O)oc3c3cc(C(=O)O)c(=O)oc23)c1 CHEMBL4859764 IC50 3.0 nM
O=c1oc2c([N+](=O)[O-])c(O)c(Br)cc2cc1-c1nnn[nH]1 CHEMBL4100677 EC50 3.0 nM
O=C1N/C(=N/c2ccccc2F)S/C1=C\c1ccc(C(=O)O)cc1 CHEMBL2392141 EC50 3.2 nM
Cc1c2nc(C(=O)O)cc(Cl)c2cc2c(Cl)cc(C(=O)O)nc12 CHEMBL4876009 IC50 3.52 nM
CC1=CC(C)=[N+]2C1=C(c1ccc(OCCn3cc(CCCCOc4cc(C(=O)O)nc5c(C)c6nc(C(=O)O)cc(O)c6cc45)nn3)cc1)c1nc(C)cn1[B-]2(F)F CHEMBL5281778 Kd 3.9 nM
CC(/C=C1\SC(=S)N(CCCC(=O)Nc2ccc(C(=O)O)c(O)c2)C1=O)=C\c1ccccc1 CHEMBL1384502 Ki 4.0 nM
N#Cc1cc(NC(=O)C(=O)O)c(Cl)c(NC(=O)C(=O)O)c1 CHEMBL1201266 EC50 4.0 nM
O=C(O)c1cc(=O)c2cc(F)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1 CHEMBL2392160 Ki 4.12 nM
O=C(Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12)c1ccc(Cl)cc1 CHEMBL2392170 Ki 4.79 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392174 Ki 5.18 nM
[3H]C([3H])([3H])Oc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2425818 Kd 5.27 nM
COc1ccc(C(=O)Nc2cc(Cl)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392167 Ki 5.5 nM
CC1=CC(C)=[N+]2C1=C(c1ccc(OCCn3cc(CCCCCOc4cc(C(=O)O)nc5c(C)c6nc(C(=O)O)cc(O)c6cc45)nn3)cc1)c1nc(C)cn1[B-]2(F)F CHEMBL5285029 IC50 5.6 nM
O=[N+]([O-])c1cc(C(=C(Cl)Cl)c2cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c2)cc([N+](=O)[O-])c1O CHEMBL3347474 EC50 6.0 nM
O=C(O)c1cc2c(oc1=O)c(-c1ccccc1F)cc1cc(C(=O)O)c(=O)oc12 CHEMBL4861414 IC50 6.0 nM
O=C(O)c1cc2c(oc1=O)c(-c1cccc(F)c1)cc1cc(C(=O)O)c(=O)oc12 CHEMBL4869539 IC50 6.0 nM
COc1cc(C(=O)O)nc2c(C)c3nc(C(=O)O)cc(OC)c3cc12 CHEMBL4852667 IC50 6.11 nM
CC1=CC(C)=[N+]2C1=C(c1ccc(OCCn3cc(CCCOc4cc(C(=O)O)nc5c(C)c6nc(C(=O)O)cc(O)c6cc45)nn3)cc1)c1nc(C)cn1[B-]2(F)F CHEMBL5289040 Kd 7.4 nM
CC1=CC(C)=[N+]2C1=C(c1ccc(OCCn3cc(CCOCCOc4cc(C(=O)O)nc5c(C)c6nc(C(=O)O)cc(O)c6cc45)nn3)cc1)c1nc(C)cn1[B-]2(F)F CHEMBL5288015 IC50 7.8 nM
CC(C)c1ccc(-c2cc3cc(C(=O)O)c(=O)oc3c3cc(C(=O)O)c(=O)oc23)cc1 CHEMBL4848109 IC50 8.0 nM
O=C(O)c1cc2cc3cc(C(=O)O)c(=O)oc3c(Br)c2oc1=O CHEMBL4850743 IC50 9.31 nM
COc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)cc1 CHEMBL4175848 Ki 10.0 nM
O=C(Nc1cc(F)cc2c(=O)cc(C(=O)O)oc12)c1ccc(Cl)c(Cl)c1 CHEMBL2392161 Ki 11.5 nM
O=C(O)c1cc(=O)c2c(ccc3c(=O)cc(C(=O)O)[nH]c32)[nH]1 CHEMBL3277775 EC50 13.0 nM
O=c1oc2c([N+](=O)[O-])c(O)c([N+](=O)[O-])cc2cc1-c1nnn[nH]1 CHEMBL4079816 IC50 13.0 nM
CCCCc1cc2c(=O)cc(C(=O)O)[nH]c2c2c(=O)cc(C(=O)O)[nH]c12 CHEMBL150764 EC50 13.0 nM
COc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c(F)c1 CHEMBL4159575 IC50 14.0 nM
O=C(Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12)c1ccc2c(c1)OCO2 CHEMBL2392178 Ki 15.0 nM
O=C(O)c1cc2c(oc1=O)c(-c1cccs1)cc1cc(C(=O)O)c(=O)oc12 CHEMBL4865638 IC50 15.0 nM
O=C(O)c1cc2c(oc1=O)c(Br)cc1cc(-c3nnn[nH]3)c(=O)oc12 CHEMBL4856029 IC50 15.9 nM
O=C(O)c1sc2c(Br)c(Br)sc2c1O CHEMBL2037456 EC50 16.0 nM
O=C(O)c1cc2c(oc1=O)c(-c1ccccc1)cc1cc(C(=O)O)c(=O)oc12 CHEMBL4856069 IC50 16.0 nM
O=C(O)c1cc2sc3cc(C(=O)O)sc3c2s1 CHEMBL4865971 IC50 20.0 nM
COc1ccc(C(=O)Nc2cc(OC)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2425823 Ki 20.5 nM
COc1ccccc1-c1cc2cc(C(=O)O)c(=O)oc2c2cc(C(=O)O)c(=O)oc12 CHEMBL4878979 IC50 22.0 nM
O=c1oc2c(Br)c(O)c(Br)cc2cc1-c1nnn[nH]1 CHEMBL4092954 IC50 23.0 nM
COc1ccc(C(=O)Nc2cc(F)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392162 Ki 25.4 nM
CCOC(=O)C(=O)Nc1cc(C(=O)OCC(C)C)cc(NC(=O)C(=O)OCC)c1Cl CHEMBL5423540 EC50 25.5 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cn1 CHEMBL2392183 Ki 25.7 nM
O=C(O)C(=O)Nc1cc(Br)cc(NC(=O)C(=O)O)c1Cl CHEMBL5430512 EC50 25.8 nM
O=C(O)c1cc2c(oc1=O)c(Br)cc1cc(C(=O)O)c(=O)oc12 CHEMBL4848949 IC50 26.0 nM
COc1cccc(-c2c3oc(=O)c(C(=O)O)cc3cc3cc(C(=O)O)c(=O)oc23)c1 CHEMBL4847100 IC50 26.0 nM
COc1ccc(-c2cc3cc(C(=O)O)c(=O)oc3c3cc(C(=O)O)c(=O)oc23)c(F)c1 CHEMBL4875009 IC50 27.0 nM
COc1ccccc1-c1c2oc(=O)c(C(=O)O)cc2cc2cc(C(=O)O)c(=O)oc12 CHEMBL4871203 IC50 27.0 nM
CCOC(=O)C(=O)Nc1cc(Br)cc(NC(=O)C(=O)OCC)c1Cl CHEMBL5415083 EC50 28.8 nM
CCOC(=O)C(=O)Nc1cc(C#N)cc(NC(=O)C(=O)OCC)c1Cl CHEMBL2107161 EC50 29.2 nM
O=C(O)c1cc(C(=O)O)c2c(n1)C(=O)C(=O)c1cc(C(=O)O)[nH]c1-2 CHEMBL1235421 IC50 30.0 nM
O=C(O)c1cc2cc(Br)c(O)c([N+](=O)[O-])c2oc1=O CHEMBL4082281 IC50 31.0 nM
COC(=O)C(=O)Nc1cc(C(F)(F)F)cc(NC(=O)C(=O)OC)c1Cl CHEMBL5437161 EC50 31.1 nM
CC1=C(C#N)C(=C(C#N)C#N)OC1(C)c1ccc(Cl)c(Cl)c1 CHEMBL1914576 EC50 32.0 nM
O=C(O)c1cc2c(oc1=O)c(-c1ccc(F)cc1)cc1cc(C(=O)O)c(=O)oc12 CHEMBL4852718 EC50 33.0 nM
COc1ccc(C(=O)Nc2cc(C)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2425822 EC50 37.7 nM
O=c1oc2ccccc2c(O)c1Cc1c(O)c2ccccc2oc1=O CHEMBL1466 Ki 39.0 nM
Cc1cc(NC(=O)C(=O)O)c(Cl)c(NC(=O)C(=O)O)c1 CHEMBL3245049 EC50 41.8 nM
Cc1c2oc(=O)c(C(=O)O)cc2cc2cc(C(=O)O)c(=O)oc12 CHEMBL4862654 IC50 42.0 nM
COC(=O)c1cnn(-c2ccc(F)cc2F)c1/C=N/NC(=S)NC(C)(C)C CHEMBL1708510 Ki 42.2 nM
O=C(O)COc1ccc(/C=C2\SC(=O)NC2=O)cc1 CHEMBL2425825 Ki 50.8 nM
O=C(O)c1cc(=O)c2c(OCC(O)COc3cccc4oc(C(=O)O)cc(=O)c34)cccc2o1 CHEMBL428880 EC50 52.0 nM
O=C(O)c1cc(=O)c2c(CCC(O)CCc3cccc4oc(C(=O)O)cc(=O)c34)cccc2o1 CHEMBL3558475 EC50 52.0 nM
O=C(O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 CHEMBL559337 EC50 54.0 nM
O=C(O)c1cc2cc(Br)c(O)c(Br)c2oc1=O CHEMBL4081238 IC50 56.0 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)nc1 CHEMBL2392182 Ki 56.8 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccc(F)cc1F CHEMBL4171782 IC50 60.0 nM
Cc1c(C(=O)O)sc2c(Br)csc12 CHEMBL1914588 EC50 61.0 nM
O=C(O)C(=O)Nc1cc(C(F)(F)F)cc(NC(=O)C(=O)O)c1Cl CHEMBL3245052 EC50 63.3 nM
CN(C)c1c(NC(=O)C(=O)O)cc(C#N)cc1NC(=O)C(=O)O CHEMBL5418035 EC50 64.6 nM
O=C(Nc1cc(C(F)(F)F)cc(NC(=O)C(=O)OC2CC2)c1Cl)C(=O)OC1CC1 CHEMBL5424229 EC50 75.0 nM
CCOC(=O)C(=O)Nc1cc(C(F)(F)F)cc(NC(=O)C(=O)OCC)c1Cl CHEMBL3245030 EC50 76.0 nM
CCOC(=O)C(=O)Nc1cccc(NC(=O)C(=O)OCC)c1Cl CHEMBL3245010 EC50 79.5 nM
O=C(Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12)c1ccccc1 CHEMBL2392168 Ki 81.6 nM
COc1ccc(C(=O)Nc2cc(F)ccc2-c2nnn[nH]2)cc1 CHEMBL4171326 IC50 82.0 nM
COc1c(NC(=O)C(=O)O)cc(C#N)cc1NC(=O)C(=O)O CHEMBL5410743 EC50 92.1 nM
CCOc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392175 Ki 98.4 nM
O=C(Nc1cc(C(F)(F)F)cc(NC(=O)C(=O)OC2CCC2)c1Cl)C(=O)OC1CCC1 CHEMBL5399225 EC50 98.6 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 IC50 100.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccc(Cl)cc1Cl CHEMBL4171772 IC50 110.0 nM
COc1ccc(C(=O)Nc2ccc(Br)cc2-c2nnn[nH]2)cc1 CHEMBL4160729 IC50 110.0 nM
CCOC(=O)c1cc(=O)c2cc(F)cc(NC(=O)c3ccc(OC)cc3)c2o1 CHEMBL2392163 EC50 112.0 nM
O=C(O)c1cc(=O)c2cc(F)cc(NC(=O)c3cccc(Cl)c3Cl)c2o1 CHEMBL2392159 Ki 119.0 nM
COc1ccccc1-c1cc2cc(C(=O)O)c(=O)oc2cc1O CHEMBL4854346 IC50 120.0 nM
O=C(O)C(=O)Nc1cc(C(=O)O)cc(NC(=O)C(=O)O)c1Cl CHEMBL5436420 EC50 125.0 nM
Cc1cccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)c1 CHEMBL2392169 Ki 128.0 nM
O=C(O)c1cc2cc(Br)c(O)cc2oc1=O CHEMBL4077503 IC50 130.0 nM
O=C(Nc1cc(Cl)cc2c(=O)cc(C(=O)O)oc12)c1ccccc1 CHEMBL2392164 Ki 138.0 nM
O=C(Nc1cc(C(F)(F)F)cc(NC(=O)C(=O)OC2CCCCC2)c1Cl)C(=O)OC1CCCCC1 CHEMBL5422437 EC50 141.0 nM
O=C(O)C(=O)Nc1cc(NC(=O)C(=O)O)cc(C(F)(F)F)c1 CHEMBL5416593 EC50 143.0 nM
N#Cc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392173 Ki 148.0 nM
COc1ccc(-c2cc3cc(C(=O)O)c(=O)oc3cc2O)cc1 CHEMBL4856916 IC50 150.0 nM
Cc1c(C(=O)O)sc2cc(Br)c(O)c(Br)c12 CHEMBL2089229 EC50 160.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccc(F)cc1 CHEMBL4169062 IC50 160.0 nM
O=C(O)c1cc2cc(-c3cccs3)c(O)cc2oc1=O CHEMBL4847144 IC50 160.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccccc1F CHEMBL4177096 IC50 170.0 nM
COC(=O)c1cnn(-c2ccc(F)cc2F)c1/C=N/NC(=S)Nc1ccc(Cl)cc1 CHEMBL1700467 IC50 171.0 nM
O=C(O)C(=O)Nc1cccc(NC(=O)C(=O)O)c1Cl CHEMBL3245042 EC50 174.0 nM
O=C(Nc1cc(Cl)cc2c(=O)cc(C(=O)O)oc12)c1ccc([N+](=O)[O-])cc1 CHEMBL2392166 Ki 183.0 nM
Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O CHEMBL3183248 EC50 190.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)C1CCCCC1 CHEMBL4162653 IC50 200.0 nM
CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1 CHEMBL225963 IC50 209.52 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccc(Cl)cc1 CHEMBL4163894 IC50 210.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1cccc(F)c1 CHEMBL4166473 IC50 210.0 nM
COC(=O)c1cnn(-c2ccc(Cl)cc2)c1/C=N/NC(=S)Nc1ccccc1 CHEMBL1709632 IC50 211.0 nM
COc1ccc(C(=O)Nc2cccc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392157 Ki 221.0 nM
COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1OC CHEMBL2392177 Ki 228.0 nM
O=C(Nc1cccc2c(=O)cc(C(=O)O)oc12)c1ccc(Br)cc1 CHEMBL2392158 Ki 233.0 nM
O=C([O-])c1cc2ccccc2c(Cc2c(O)c(C(=O)[O-])cc3ccccc23)c1O CHEMBL4784835 EC50 237.38 nM
Cc1c(C(=O)O)sc2c(-c3cccnc3)csc12 CHEMBL2037462 EC50 240.0 nM
Cc1cccc(C(=O)Nc2cc(Cl)cc3c(=O)cc(C(=O)O)oc23)c1 CHEMBL2392165 Ki 250.0 nM
O=C(O)c1cc2cc3cc(C(=O)O)c(=O)oc3c(O)c2oc1=O CHEMBL4870255 IC50 250.0 nM
Cc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(O)cc3)C2=O)cc1 CHEMBL1312928 IC50 253.3 nM
Cc1c(C(=O)O)sc2c(-c3ccsc3)csc12 CHEMBL2037463 EC50 260.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1cccs1 CHEMBL4168042 IC50 260.0 nM
COc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)cc1OC CHEMBL4167991 IC50 260.0 nM
CC(C)C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1 CHEMBL4176719 IC50 280.0 nM
COc1ccc(C(=O)Nc2ccccc2-c2nn[nH]n2)cc1 CHEMBL1704189 IC50 280.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccccc1 CHEMBL4172188 IC50 300.0 nM
O=C(O)c1cc2c(ccc3cc(C(=O)O)c(=O)oc32)oc1=O CHEMBL4879017 IC50 300.0 nM
COC(=O)c1cnn(-c2ccccc2)c1/C=N/NC(=S)NC(C)(C)C CHEMBL1720530 IC50 307.0 nM
COC(=O)c1cnn(-c2ccccc2)c1/C=N/NC(=S)Nc1ccc(Cl)cc1 CHEMBL1704074 IC50 319.0 nM
O=c1oc2c([N+](=O)[O-])cc(Br)cc2cc1-c1nnn[nH]1 CHEMBL4085211 EC50 330.0 nM
O=C(O)c1cc2cc(-c3ccccc3)c(O)cc2oc1=O CHEMBL4875041 IC50 330.0 nM
COc1ccccc1C(=O)Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12 CHEMBL2392176 Ki 331.0 nM
CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc21 CHEMBL50588 IC50 352.52 nM
Cc1cccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c1 CHEMBL4175617 IC50 360.0 nM
Cc1c(C(=O)O)sc2c(-c3cn[nH]c3)csc12 CHEMBL2037464 EC50 370.0 nM
COC(=O)c1cnn(-c2ccc(F)cc2F)c1/C=N/NC(=S)Nc1ccccc1 CHEMBL1718866 IC50 379.0 nM
O=c1oc2c(Br)cc(Br)cc2cc1-c1nnn[nH]1 CHEMBL4065291 IC50 380.0 nM
CC(=O)NCCc1ccc(O)c(-c2c(O)c(O)c3c(c2O)C(=O)c2c(cc(O)c(C(=O)O)c2C(=O)O)C3=O)c1 CHEMBL2037378 EC50 390.0 nM
COc1ccccc1C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1 CHEMBL4172440 IC50 400.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccccc1Cl CHEMBL4160515 IC50 410.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1ccco1 CHEMBL4173352 IC50 440.0 nM
CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL1707 EC50 444.0 nM
COc1c(Br)cc2cc(-c3nnn[nH]3)c(=O)oc2c1Br CHEMBL4103143 IC50 460.0 nM
CC(C)c1ccc(-c2cc3cc(C(=O)O)c(=O)oc3cc2O)cc1 CHEMBL4853043 IC50 470.0 nM
O=C(Nc1cc(Br)ccc1-c1nnn[nH]1)c1cccc(Cl)c1 CHEMBL4168406 IC50 480.0 nM
O=c1oc2cc(O)c(Br)cc2cc1-c1nnn[nH]1 CHEMBL4073902 IC50 483.0 nM
COc1ccc(NC(=O)c2cnn3c(O)cc(C4CCN(C(=O)OC(C)(C)C)CC4)nc23)cc1Cl CHEMBL1354041 EC50 506.0 nM
O=C(O)c1sc2c(Br)c(Br)sc2c1C(F)(F)F CHEMBL2035007 EC50 510.0 nM
Cc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)cc1 CHEMBL4164993 IC50 510.0 nM
COc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(C(=O)O)c(O)c3)C2=O)cc1OC CHEMBL1552304 IC50 521.8 nM
CN(C)/C=C/C(=O)c1ccc(N2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)cc1 CHEMBL1386711 IC50 529.71 nM
CC(=O)Nc1sc(/C(C#N)=C/c2ccc(Cl)c(Cl)c2)nc1-c1ccc(C)cc1 CHEMBL1424929 IC50 533.78 nM
O=C(Nc1ccc2nc(SCc3ccc(Cl)cc3)sc2c1)c1ccccc1C(=O)N1CCOCC1 CHEMBL1368962 EC50 550.0 nM
C=CCCCCCCCCc1nc(SCC(=O)O)n[nH]1 CHEMBL1500763 IC50 553.11 nM
CCN(CC)c1ccc(/C=C(/C#N)c2nc3cc(C)ccc3[nH]2)c(OC(C)C)c1 CHEMBL1353925 IC50 556.59 nM
CC(C)c1ccc(NC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccc(C(=O)O)cc2)cc1 CHEMBL1372770 IC50 560.66 nM
O=C(CCCN1C(=O)/C(=C/c2ccc3c(c2)OCO3)SC1=S)Nc1ccc(C(=O)O)cc1 CHEMBL1532025 IC50 562.83 nM
COc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3cccc(C(=O)O)c3)C2=O)cc1OC CHEMBL1487024 IC50 563.64 nM
CCCCCCCCCCCc1c(C(=O)O)sc2c(Br)csc12 CHEMBL1914590 IC50 570.0 nM
CCCOc1cc(N(CC)CC)ccc1/C=C(/C#N)c1nc2cc(C)ccc2[nH]1 CHEMBL1304179 IC50 573.4 nM
N#Cc1cc2cc(Br)cc([N+](=O)[O-])c2oc1=O CHEMBL4066109 pEC50 576.77 nM
COc1c(Br)cc2cc(C#N)c(=O)oc2c1Br CHEMBL4093683 IC50 590.0 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(Cl)c4)CC3)ncnc12 CHEMBL256470 IC50 608.24 nM
Cc1nnc(NC(=O)c2sc3nc(-c4cccs4)cc(C(F)(F)F)c3c2N)s1 CHEMBL1442537 IC50 609.68 nM
Cc1ccccc1N1CCN(c2ncnc3c2cnn3Cc2ccc(Cl)cc2)CC1 CHEMBL1325250 IC50 615.09 nM
CCC(=O)Nc1cc(Br)ccc1-c1nnn[nH]1 CHEMBL4166100 pEC50 616.6 nM
CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 CHEMBL1307717 IC50 626.47 nM
Cc1c(C(=O)O)[nH]c2c(-c3cccnc3)csc12 CHEMBL2037466 EC50 630.0 nM
CCc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(C(=O)O)cc3)C2=O)cc1 CHEMBL1413629 IC50 635.7 nM
CN(C)c1ccc(/C=C2\NC(=S)N(Cc3ccccc3)C2=O)cc1 CHEMBL1303807 IC50 650.6 nM
COc1cccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(C(=O)O)cc3)C2=O)c1 CHEMBL1367928 IC50 691.0 nM
O=C(Nc1cccc2c(=O)cc(C(=O)O)oc12)c1ccc2ccccc2n1 CHEMBL2392152 Ki 691.0 nM
Cc1ccc(C(=O)Nc2cccc3c(=O)cc(C(=O)O)oc23)cc1 CHEMBL2392155 Ki 697.0 nM
Cc1c(C(=O)O)sc2c(Br)c(Br)sc12 CHEMBL2037454 EC50 700.0 nM
CCOc1ccc(N(C)c2ccc(/C=C3/SC(=S)NC3=O)cc2)cc1 CHEMBL1300169 IC50 701.49 nM
O=C(O)c1cc2cc(-c3cccc(F)c3)c(O)cc2oc1=O CHEMBL4859675 IC50 710.0 nM
O=C(Nc1cccc2c(=O)cc(C(=O)O)oc12)c1ccc2ccccc2c1 CHEMBL2392151 Ki 714.0 nM
N#Cc1cc2c(ccc3cc(-c4nnn[nH]4)c(=O)oc32)oc1=O CHEMBL4860550 IC50 730.0 nM
COc1c(Br)cc2cc(C(=O)O)c(=O)oc2c1Br CHEMBL4105535 IC50 750.0 nM
Cc1ccc(Cn2ncc3c(N4CCN(c5ccccc5C)CC4)ncnc32)cc1 CHEMBL1428840 IC50 760.98 nM
Nc1[nH]c2cc([N+](=O)[O-])ccc2c1-c1ccccn1 CHEMBL1430125 IC50 786.83 nM
O=C(O)c1cc2cc(-c3ccccc3F)c(O)cc2oc1=O CHEMBL4875771 IC50 800.0 nM
O=C(CCCN1C(=O)/C(=C/c2ccc3c(c2)OCO3)SC1=S)Nc1cccc(C(=O)O)c1 CHEMBL1560901 IC50 802.74 nM
O=C(CCCN1C(=O)/C(=C\c2ccccc2)SC1=S)Nc1cccc(C(=O)O)c1 CHEMBL1444708 IC50 804.54 nM
Cc1ccccc1C(=O)Nc1cc(Br)ccc1-c1nnn[nH]1 CHEMBL4161574 IC50 810.0 nM
COc1cccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c1 CHEMBL4164556 IC50 810.0 nM
CC(=O)C(=Cc1cc(O)c(O)c([N+](=O)[O-])c1)C(C)=O CHEMBL167055 EC50 820.0 nM
CC(C)c1ccc(N2C(=O)/C(=C/N(C)C)SC2=S)cc1 CHEMBL1464544 IC50 834.53 nM
CC/N=C1\S/C(=C\c2cc(OC)c(N3CCCC3)cc2OC)C(=O)N1CC CHEMBL1975147 IC50 898.37 nM
CC(C)(C)c1ccc(OCCC(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL1333832 IC50 929.42 nM
Cc1c(C(=O)O)sc2c(C3CC3)csc12 CHEMBL2037461 EC50 950.0 nM
CN1CC=C2C(C#N)=C(N)C(C#N)(C#N)C(c3ccsc3)C2C1 CHEMBL1497386 IC50 990.68 nM