CNc1nc(NCc2ccc(NS(C)(=O)=O)cc2Cl)cc(-c2ccccn2)n1 CHEMBL3342358 EC50 0.06 nM
CNc1nc(NCc2ccc(NS(C)(=O)=O)cc2)cc(-c2ccccn2)n1 CHEMBL3342376 EC50 0.18 nM
CNc1nc(NCc2ccc(NC(C)=O)cc2F)cc(-c2ccccn2)n1 CHEMBL3342379 EC50 0.35 nM
CNc1nc(NCc2ccc(NC(C)=O)cc2)cc(-c2ccccn2)n1 CHEMBL3342377 EC50 0.55 nM
CNc1nc(NCc2ccc(Cl)cc2Cl)cc(-c2ccccn2)n1 CHEMBL3342370 EC50 0.8 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccc(F)cc1)CC(=O)N2 CHEMBL4072160 EC50 1.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1cc(F)cc3c1OCOC3)CC(=O)N2 CHEMBL4100119 EC50 1.5 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccccc1Cl)CC(=O)N2 CHEMBL4083614 EC50 2.0 nM
COc1ccc(CCOC2CC(=O)Nc3c2c(C)nn3-c2ncnc3nc[nH]c23)cc1 CHEMBL4089047 EC50 2.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OC1CCCC1)CC(=O)N2 CHEMBL4104345 EC50 2.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCCc1ccccc1)CC(=O)N2 CHEMBL4099134 EC50 3.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCC(=O)c1ccc(F)cc1)CC(=O)N2 CHEMBL4101617 EC50 3.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(NC(=O)c1ccccc1)CC(=O)N2 CHEMBL4062704 EC50 3.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(NC(=O)Cc1ccccc1)CC(=O)N2 CHEMBL4098394 EC50 3.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(NC(=O)Cc1cccs1)CC(=O)N2 CHEMBL4071347 EC50 3.0 nM
CNc1nc(NCc2ccccc2Cl)cc(-c2ccccn2)n1 CHEMBL5207240 EC50 3.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OC(=O)c1ccc(F)cc1)CC(=O)N2 CHEMBL4063554 EC50 4.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccc(Cl)cc1Cl)CC(=O)N2 CHEMBL4091396 EC50 4.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccc(C#N)cc1)CC(=O)N2 CHEMBL4067834 EC50 4.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccccc1F)CC(=O)N2 CHEMBL4082109 EC50 4.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)NCc1ccc(F)cc1)CC(=O)N2 CHEMBL4059978 EC50 4.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCC(C)C)CC(=O)N2 CHEMBL4080106 EC50 4.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccc(C(C)C)cc1)CC(=O)N2 CHEMBL4081167 EC50 5.0 nM
Cc1noc(C)c1COC1CC(=O)Nc2c1c(C)nn2-c1ncnc2nc[nH]c12 CHEMBL4105417 EC50 5.0 nM
CCC(C(=O)NC1CC(=O)Nc2c1c(C)nn2-c1ncnc2nc[nH]c12)c1ccccc1 CHEMBL4090669 EC50 5.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)NCc1ccccc1)CC(=O)N2 CHEMBL4081885 EC50 5.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OC(=O)Cc1ccccc1)CC(=O)N2 CHEMBL4060772 EC50 6.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)NCc1ccc3c(c1)OCO3)CC(=O)N2 CHEMBL4075137 EC50 7.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCc1ccccc1C#N)CC(=O)N2 CHEMBL4104470 EC50 8.0 nM
CCCCCCCCOC1CC(=O)Nc2c1c(C)nn2-c1ncnc2nc[nH]c12 CHEMBL4087979 EC50 8.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(c1ccc(F)cc1Cl)CC(=O)N2 CHEMBL4077818 EC50 9.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCCn1nccc1C)CC(=O)N2 CHEMBL4086570 EC50 10.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)Nc1ccccc1)CC(=O)N2 CHEMBL4068635 EC50 10.0 nM
CNc1nc(NCC2CCCCC2)cc(-c2ccccn2)n1 CHEMBL3342366 EC50 11.0 nM
O=S(=O)(NC[C@H]1CC[C@H](CNc2cc(-c3ccccn3)nc(NC3CC3)n2)CC1)c1cccc(F)c1 CHEMBL3341764 EC50 11.0 nM
CNc1nc(NCc2ccc(OC(F)(F)F)cc2)cc(-c2ccccn2)n1 CHEMBL3342374 EC50 13.0 nM
CNc1nc(NCc2ccc(Cl)cc2)cc(-c2ccccn2)n1 CHEMBL3342367 EC50 15.0 nM
Cc1cc(NCc2ccc(F)cc2)n2ncc(-c3ccccn3)c2n1 CHEMBL5182651 EC50 15.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCCn1cccn1)CC(=O)N2 CHEMBL4096749 EC50 16.0 nM
Cc1cc(C)n(CCOC2CC(=O)Nc3c2c(C)nn3-c2ncnc3nc[nH]c23)n1 CHEMBL4078723 EC50 16.0 nM
CNc1nc(NC2CCCCC2)cc(-c2ccccn2)n1 CHEMBL5195894 EC50 16.0 nM
Cc1cc(NC(C)c2ccc(F)cc2)n2ncc(-c3ccccn3)c2n1 CHEMBL5177479 EC50 17.0 nM
Cc1cc(N2CCCC2c2ccccc2)n2ncc(-c3ccccn3)c2n1 CHEMBL5192920 EC50 17.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)N(C)c1nccs1)CC(=O)N2 CHEMBL4101801 EC50 18.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(c1ccc(OC(C)C)cc1)CC(=O)N2 CHEMBL4093273 EC50 18.0 nM
CNc1nc(Oc2ccccc2)cc(-c2ccccn2)n1 CHEMBL5200611 EC50 23.0 nM
CNc1nc(NC2(c3ccc(Cl)cc3)CCC2)cc(-c2ccccn2)n1 CHEMBL3342373 EC50 25.0 nM
CNC(=O)c1ccc(CNc2cc(-c3ccccn3)nc(NC)n2)cc1 CHEMBL3342378 EC50 30.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)N(C)c1ccccc1)CC(=O)N2 CHEMBL4089753 EC50 32.0 nM
CNc1nc(NCc2ccc(S(C)(=O)=O)cc2)cc(-c2ccccn2)n1 CHEMBL3342375 EC50 36.0 nM
N#Cc1ccc(N2CCN(Cc3cn4cc(Cl)ccc4n3)CC2)nc1 CHEMBL3092413 EC50 56.0 nM
FC(F)(F)CNc1nc(NCc2ccc(Cl)cc2)cc(-c2ccccn2)n1 CHEMBL3342371 EC50 60.0 nM
Cc1cc(NC(C)(C)c2ccc(F)cc2)n2ncc(-c3ccccn3)c2n1 CHEMBL5180126 EC50 63.0 nM
CNc1nc(NCC(C)(C)C)cc(-c2ccccn2)n1 CHEMBL3342365 EC50 73.0 nM
CNC(=O)C(Nc1cc(C)nc2c(-c3ccccn3)cnn12)c1ccc(F)cc1 CHEMBL5181574 EC50 78.0 nM
Cc1cc(N2CCCC2c2cccnc2)n2ncc(-c3ccccn3)c2n1 CHEMBL5181167 EC50 79.0 nM
Cc1nc(NCc2ccc(Cl)cc2)cc(-c2ccccn2)n1 CHEMBL3342372 EC50 81.0 nM
CNc1nc(NCc2ccncc2)cc(-c2ccccn2)n1 CHEMBL3342368 EC50 87.0 nM
Cc1cc(N2CCC(c3ccccc3)C2)n2ncc(-c3ccccn3)c2n1 CHEMBL5170821 EC50 142.0 nM
CNc1nc(NCC2CC2)cc(-c2ccccn2)n1 CHEMBL3342359 EC50 164.0 nM
CCc1nc(CN2C[C@@H](C(=O)NCc3ccccc3Cl)[C@H](c3cccnc3)C2)c[nH]1 CHEMBL3092410 EC50 190.0 nM
O=C1/C(=C/NCCCO)C(c2ccccc2)=NN1c1nc2ccccc2s1 CHEMBL4093427 EC50 200.0 nM
O=S(=O)(NC[C@H]1CC[C@H](CNc2nc(NC3CC3)cc(-c3ccccn3)n2)CC1)c1cccc(F)c1 CHEMBL3342357 EC50 202.0 nM
CC(C)(C)c1cc(C(=O)N/N=C/c2ccc(O)cc2O)[nH]n1 CHEMBL4069386 EC50 240.0 nM
NC(Cc1cnc[nH]1)c1nc2ccc(-c3ccccc3)cc2c(=O)[nH]1 CHEMBL5193472 EC50 251.0 nM
CCc1nc(CN2C[C@H](C(=O)NCc3ccccc3Cl)[C@@H](c3cccnc3)C2)c[nH]1 CHEMBL3092411 EC50 310.0 nM
C=CCN1c2c(n(C)c(=O)n(C)c2=O)NC1N/N=C/c1ccc(O)cc1O CHEMBL4088923 EC50 340.0 nM
Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(c1ccc(F)cc1F)CC(=O)N2 CHEMBL4066831 EC50 460.0 nM
CNc1cc(-c2ccccn2)nc(NC2CCCCC2)n1 CHEMBL5195424 EC50 487.0 nM
FC(F)(F)Oc1ccc(CNc2nc(NCC3CC3)cc(-c3ccccn3)n2)cc1 CHEMBL3342362 EC50 600.0 nM
Cn1cc(-c2ccc3nc(C(N)CCOCc4ccccc4)[nH]c(=O)c3c2)cn1 CHEMBL5203229 EC50 641.0 nM
OCC(O)/C=N/Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1 CHEMBL3198662 EC50 750.0 nM