COc1ccc(Cc2ccnc(N3CCc4c(C(=O)NC5CCN(CCO)CC5)cccc43)c2)cc1F CHEMBL4852000 EC50 1.06 nM
NC(=O)c1cccc2c1CCN2c1cccc(Cc2cccc(C(F)(F)F)c2)n1 CHEMBL4846914 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4872227 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1ccnc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4865057 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cncc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4869139 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cncc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4868643 EC50 1.1 nM
O=C(N[C@H]1CCOC1)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)c[n+]([O-])c1 CHEMBL4858187 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)c[n+]([O-])c1 CHEMBL4878069 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(F)c2)ccn1 CHEMBL4846416 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(F)c2)ccn1 CHEMBL4848812 EC50 1.1 nM
CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(F)c2)ccn1 CHEMBL4851368 EC50 1.1 nM
CNC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)cc(C)n1 CHEMBL4855829 EC50 1.1 nM
O=C(N[C@H]1CCOC1)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(F)c2)ccn1 CHEMBL4875443 EC50 1.1 nM
O=C(NC[C@@H](O)CO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4853555 EC50 1.1 nM
O=C(NC[C@H](O)CO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4865653 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Oc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4863386 EC50 1.1 nM
O=C(NCCCO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4863198 EC50 1.1 nM
C[C@@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4866463 EC50 1.1 nM
N#CCNC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4848606 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4858042 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Sc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4871052 EC50 1.1 nM
O=C(NC[C@@H](O)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4863576 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4861950 EC50 1.1 nM
CN(C)CCNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4847685 EC50 1.1 nM
O=C(NC(CO)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4866193 EC50 1.1 nM
CN(C)CCNC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4876504 EC50 1.1 nM
O=C(NC(CO)CO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4864049 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cncc(Cc2cccc(C(F)(F)F)c2)n1 CHEMBL4877909 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)n2)ccn1 CHEMBL4864476 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)n2)ccn1 CHEMBL4867044 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4848379 EC50 1.1 nM
CN(C)CCNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4855290 EC50 1.1 nM
O=C(Nc1ccncc1)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4875102 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cncc(Cl)c2)ccn1 CHEMBL4863447 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cncc(C(F)(F)F)c2)ccn1 CHEMBL4850812 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cncc(C(F)(F)F)c2)ccn1 CHEMBL4846330 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccnc(C(F)(F)F)c2)ccn1 CHEMBL4846775 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cnc(F)c(Cl)c2)ccn1 CHEMBL4876282 EC50 1.1 nM
CN1CCC(NC(=O)c2cccc3c2CCN3c2cc(Cc3cccc(C(F)(F)F)c3)ccn2)CC1 CHEMBL4854218 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1C(F)(F)F CHEMBL4849904 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(Cl)c(F)c2)ccn1 CHEMBL4865996 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(Cl)c2)ccn1 CHEMBL4852273 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(C(F)(F)F)c2)ccn1 CHEMBL4877494 EC50 1.1 nM
CC(=O)c1cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)ccc1F CHEMBL4878221 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4860064 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc3c(c2)CCO3)ccn1 CHEMBL4852339 EC50 1.1 nM
COc1cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)ccc1F CHEMBL4845846 EC50 1.1 nM
N#Cc1cc(F)cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)c1 CHEMBL4877713 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(Cl)c2)ccn1 CHEMBL4872112 EC50 1.1 nM
COc1cc(F)cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)c1 CHEMBL4868214 EC50 1.1 nM
COc1ncc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cn1 CHEMBL4858047 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cnc(Cl)nc2)ccn1 CHEMBL4848378 EC50 1.1 nM
COc1cc(Cc2ccnc(N3CCc4c(C(=O)NCCO)cccc43)c2)ccc1F CHEMBL4877278 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(C(F)(F)F)c2)ccn1 CHEMBL4850054 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccc3c(c2)CCO3)ccn1 CHEMBL4869015 EC50 1.1 nM
O=C(NC1CCN(CCO)CC1)c1cccc2c1CCN2c1cc(Cc2ccc3c(c2)CCO3)ccn1 CHEMBL4861454 EC50 1.1 nM
CC(=O)c1cc(Cc2ccnc(N3CCc4c(C(=O)NC5CCN(CCO)CC5)cccc43)c2)ccc1F CHEMBL4861199 EC50 1.1 nM
CC(=O)c1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1F CHEMBL4869262 EC50 1.1 nM
COc1ncc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1F CHEMBL4859593 EC50 1.1 nM
COc1ncc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1Cl CHEMBL4851800 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cn1 CHEMBL4876095 EC50 1.1 nM
N#Cc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cn1 CHEMBL4870751 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(CO)c(F)c2)ccn1 CHEMBL4870029 EC50 1.1 nM
N#Cc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1F CHEMBL4864397 EC50 1.1 nM
O=C(NC1CCN(CCO)CC1)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4867659 EC50 1.1 nM
O=C(NC1CCN(CCO)CC1)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4865128 EC50 1.1 nM
O=C(NC1CCN(CCO)CC1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4846586 EC50 1.1 nM
O=C(NCCCN1CCOCC1)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4856676 EC50 1.1 nM
O=C(NCCCN1CCCC1)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4875342 EC50 1.1 nM
COc1cccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)c1 CHEMBL4856786 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1C CHEMBL4868562 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1Cl CHEMBL4877524 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc3c(c2)OCO3)ccn1 CHEMBL4852734 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccco2)ccn1 CHEMBL4866434 EC50 1.1 nM
Cc1noc(C)c1Cc1ccnc(N2CCc3c(C(N)=O)cccc32)c1 CHEMBL4853689 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccoc2)ccn1 CHEMBL4854849 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4851533 EC50 1.1 nM
COc1cc(Cl)cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)c1 CHEMBL4846333 EC50 1.1 nM
O=C(NCCO)c1c(F)ccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4865786 EC50 1.1 nM
O=C(NC1CCN(CCO)CC1)c1c(F)ccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4872358 EC50 1.1 nM
CCOc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1F CHEMBL4853824 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cccc3ncccc23)ccn1 CHEMBL4868799 EC50 1.1 nM
O=C(NC(CO)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4854092 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(O)c2)ccn1 CHEMBL4876057 EC50 1.1 nM
COc1cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)ccc1Cl CHEMBL4865124 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(F)c2)ccn1 CHEMBL4871344 EC50 1.1 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cccc3[nH]ccc23)ccn1 CHEMBL4849698 EC50 1.1 nM
COc1c(F)cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1F CHEMBL4870024 EC50 1.1 nM
NC(=O)c1c(F)ccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4869072 EC50 1.1 nM
O=C(NC[C@@H](O)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4856937 EC50 1.1 nM
O=C(NC[C@H](O)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4864933 EC50 1.1 nM
O=C(NCC(O)c1ccccn1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4875163 EC50 1.1 nM
O=C(NCC(O)c1cccnc1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4878142 EC50 1.1 nM
O=C(NCC(O)c1ccncc1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4877331 EC50 1.1 nM
O=C1CCC(NC(=O)c2cccc3c2CCN3c2cc(Cc3cc(F)c(F)c(F)c3)ccn2)CN1 CHEMBL4861879 EC50 1.1 nM
CC(=O)NCCNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4870900 EC50 1.1 nM
COCC(O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4867681 EC50 1.1 nM
O=C(NCCN1CCCC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4855414 EC50 1.1 nM
C[C@H](O)[C@@H](CO)NC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4866874 EC50 1.1 nM
O=C(N[C@H]1CCOC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4853193 EC50 1.1 nM
COC[C@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4854146 EC50 1.1 nM
COC[C@@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4846977 EC50 1.1 nM
O=C(NCCn1ccnc1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4871971 EC50 1.1 nM
O=C(NC(CO)CO)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4862500 EC50 1.1 nM
O=C(NC[C@@H](O)CO)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4847708 EC50 1.1 nM
O=C(NCC(O)Cc1cccnc1)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4856315 EC50 1.1 nM
COC[C@H](O)CNC(=O)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4869524 EC50 1.1 nM
CC(=O)NCCNC(=O)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4858574 EC50 1.1 nM
O=C(N[C@@H]1CCNC1=O)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4869305 EC50 1.1 nM
O=C(N[C@H]1CCNC1=O)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4875637 EC50 1.1 nM
O=C(NC[C@@H](O)c1cccnc1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4847735 EC50 1.1 nM
COC[C@@H](O)CNC(=O)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4863091 EC50 1.1 nM
O=C(N[C@@H]1CCNC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4874627 EC50 1.1 nM
O=C(N[C@H]1CCNC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4860294 EC50 1.1 nM
O=C(NCCc1cnc[nH]1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4858448 EC50 1.1 nM
O=C(NCC1(CO)COC1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4853557 EC50 1.1 nM
COC[C@@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(OC)c(F)c2)ccn1 CHEMBL4849398 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(=O)N[C@H]5CCNC5=O)cccc43)c2)cc1F CHEMBL4851069 EC50 1.1 nM
O=C(NCCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4869130 EC50 1.1 nM
O=C(NCCF)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4853351 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c3ccc(F)c4C(=O)NCCO)c2)cc1F CHEMBL4863562 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c3ccc(F)c4C(=O)NCCF)c2)cc1F CHEMBL4868949 EC50 1.1 nM
O=C(NCC(O)CF)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4855110 EC50 1.1 nM
Cc1c(Cc2cccc(C(F)(F)F)c2)ccnc1N1CCc2c(C(=O)NCCO)cccc21 CHEMBL4850541 EC50 1.1 nM
O=C(NCC(O)CF)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4849056 EC50 1.1 nM
O=C(N[C@H]1CCNC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4863613 EC50 1.1 nM
O=C(NC[C@@H](F)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4866626 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4860274 EC50 1.1 nM
O=C(N[C@H]1CCNC1=O)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4863658 EC50 1.1 nM
O=C(NC[C@@H](F)CO)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4855646 EC50 1.1 nM
O=C(NCC(F)CF)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4856051 EC50 1.1 nM
COC[C@@H](F)CNC(=O)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4856557 EC50 1.1 nM
C[C@@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4858311 EC50 1.1 nM
C[C@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4878629 EC50 1.1 nM
O=C(NC[C@H](F)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4874029 EC50 1.1 nM
O=C(NC[C@H](F)CO)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4876839 EC50 1.1 nM
O=C(NC[C@H](O)CF)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4852404 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1ccnc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4873808 EC50 1.1 nM
CC(=O)c1cccc(Cc2cc(N3CCc4c(C(=O)NCCO)cccc43)ccn2)c1 CHEMBL4851936 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4850965 EC50 1.1 nM
O=C(NCCO)c1cccc2c1CCN2c1ccnc(Cc2ccc(F)c(C(F)(F)F)c2)c1 CHEMBL4865910 EC50 1.1 nM
O=C(NCCF)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4853939 EC50 1.1 nM
COC[C@H](O)CNC(=O)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4849645 EC50 1.1 nM
O=C(NCC(O)CF)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4879330 EC50 1.1 nM
O=C(NC[C@@H](F)CO)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4849970 EC50 1.1 nM
O=C(N[C@H]1CCNC1=O)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4851577 EC50 1.1 nM
C[C@@H](O)CNC(=O)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4869851 EC50 1.1 nM
C[C@H](O)CNC(=O)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4855055 EC50 1.1 nM
COc1ccc(Cc2cc(N3CCc4c(C(=O)NC[C@@H](O)CF)cccc43)ccn2)cc1F CHEMBL4866746 EC50 1.1 nM
COc1ccc(Cc2cc(N3CCc4c(C(=O)NC[C@H](O)CF)cccc43)ccn2)cc1F CHEMBL4873801 EC50 1.1 nM
O=C(NC[C@H](O)CF)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4854701 EC50 1.1 nM
O=C(NC[C@@H](O)CF)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4866543 EC50 1.1 nM
O=C(NC[C@@H](O)CF)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4870894 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(=O)NC[C@@H](F)CO)cccc43)c2)cc1F CHEMBL4878529 EC50 1.1 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(=O)NCC5(CO)COC5)cccc43)c2)cc1F CHEMBL4862529 EC50 1.1 nM
O=C(NCCOCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4851394 EC50 1.1 nM
O=C(NCCOCCO)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4863892 EC50 1.1 nM
O=C(NCCF)c1cccc2c1CCN2c1cc(Cc2ccc3occc3c2)ccn1 CHEMBL4856011 EC50 1.1 nM
Cc1nn(-c2ccnc(Cc3cc(F)cc(C(F)F)c3)c2)c2c1C(=O)NCC2 CHEMBL5277794 pEC50 2.512 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(=O)NCCO)cccc43)c2)cc1F CHEMBL4849417 EC50 3.11 nM
Cc1nn(-c2ccnc(Cc3cc(F)cc(C(F)(F)F)c3)c2)c2c1C(=O)NCC2 CHEMBL5278598 pEC50 3.981 nM
Cc1nn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)cc1C(=O)NCCO CHEMBL4226295 EC50 5.2 nM
O=C(N[C@H]1CCOC1)c1cccc2c1CCN2c1cncc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4847995 EC50 5.21 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(=O)NCCF)cccc43)c2)cc1F CHEMBL4861734 EC50 5.54 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1F CHEMBL4862064 EC50 5.57 nM
Cc1nn(-c2ccnc(Cc3cc(F)cc(OC(F)F)c3)c2)c2c1C(=O)NCC2 CHEMBL5287320 pEC50 6.31 nM
CN(C)CC(O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4864354 EC50 6.76 nM
CNC(=O)c1cccc2c1CCN2c1cncc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4871721 EC50 7.45 nM
COc1ccc(Cc2ccnc(N3CCc4c(C(=O)NCCOCCO)cccc43)c2)cc1F CHEMBL4869490 EC50 8.56 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4873666 EC50 8.87 nM
COCCNC(=O)c1cn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)nc1C CHEMBL4229128 EC50 9.6 nM
O=C(Nc1cnn(CCO)c1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4861218 EC50 9.74 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4868910 EC50 9.76 nM
O=C1NCCc2c1cnn2-c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL5287006 pEC50 10.0 nM
Cc1nn(-c2cncc(Cc3cc(F)cc(C(F)(F)F)c3)c2)c2c1C(=O)NCC2 CHEMBL5282094 pEC50 10.0 nM
O=C(N[C@H]1CCOC1)c1cccc2c1CCN2c1ccnc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL4868685 EC50 10.3 nM
CC(=O)c1cc(Cc2ccnc(N3CCc4c(C(=O)NCCO)cccc43)c2)ccc1F CHEMBL4862971 EC50 10.7 nM
COc1ccc(Cc2ccnc(N3CCc4c3ccc(F)c4C(=O)NCCNC(C)=O)c2)cc1F CHEMBL4872333 EC50 10.9 nM
Cc1cc(-c2sc(Cc3cc(F)cc(C(F)(F)F)c3)nc2C)ccc1C(N)=O CHEMBL4059658 EC50 11.0 nM
CC(=O)c1cccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)c1 CHEMBL4857429 EC50 11.2 nM
N#Cc1cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)ccc1F CHEMBL4865212 EC50 11.7 nM
O=C(NC[C@@H](F)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4862838 EC50 12.2 nM
O=C(N[C@H]1CCOC1)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4862614 EC50 12.3 nM
O=C1NCCc2c1cnn2-c1cccc(Cc2cc(F)cc(C(F)(F)F)c2)c1 CHEMBL5289682 pEC50 12.59 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4749272 EC50 12.6 nM
O=C(NCCO)c1cccc2c1CCN2c1ccnc(Cc2cc(F)cc(Cl)c2)c1 CHEMBL4871179 EC50 12.9 nM
Cc1nn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c(C)c1C(=O)NCCO CHEMBL4229063 EC50 15.0 nM
CC(=O)c1ccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cc1 CHEMBL4875581 EC50 16.0 nM
COCCNC(=O)c1c(C)nn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1C CHEMBL4226695 EC50 17.0 nM
Cc1cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)cnc1F CHEMBL4869553 EC50 17.4 nM
CNC(=O)CCNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4846042 EC50 18.0 nM
COc1ccc(Cc2ccnc(N3CCc4c3ccc(F)c4C(=O)NC[C@@H](F)CO)c2)cc1F CHEMBL4864048 EC50 18.2 nM
O=C(NCCN1CCNC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4848165 EC50 18.3 nM
O=C1NCCc2c1cnn2-c1ccnc(Cc2cc(F)cc(C(F)F)c2)c1 CHEMBL5287950 pEC50 19.95 nM
Cc1nn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c(CO)c1C(=O)NCCO CHEMBL4228912 EC50 21.0 nM
CC(=O)Oc1cccc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)c1 CHEMBL4857269 EC50 21.4 nM
COC[C@@H](O)CNC(=O)c1cccc2c1CCN2c1ccnc(Cc2cc(F)c(F)c(F)c2)c1 CHEMBL4856037 EC50 21.9 nM
Cc1cc(-c2cc(Cc3cc(F)cc(C(F)(F)F)c3)nn2C)ccc1C(N)=O CHEMBL4087237 EC50 23.0 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(OC(F)(F)F)c2)ccn1 CHEMBL4871459 EC50 23.1 nM
Cn1cc(NC(=O)c2cccc3c2CCN3c2cc(Cc3cc(F)c(F)c(F)c3)ccn2)cn1 CHEMBL4860543 EC50 23.6 nM
Cc1cc(-c2sc(Cc3cc(F)cc(Cl)c3)nc2C)ccc1C(N)=O CHEMBL4075971 EC50 25.0 nM
O=C1CCCc2c1cnn2-c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL5284809 pEC50 25.12 nM
CN1CCc2c(cnn2-c2cc(Cc3cc(F)cc(C(F)(F)F)c3)ccn2)C1=O CHEMBL5274093 pEC50 25.12 nM
O=C1NCCc2c1cnn2-c1ccnc(Cc2cc(F)cc(C(F)(F)F)c2)c1 CHEMBL5284353 EC50 27.5 nM
O=C(NCCO)c1cccc(-c2cccc3oc(Cc4cccc(C(F)(F)F)c4)cc23)c1 CHEMBL3299119 pEC50 28.18 nM
COCCNC(=O)c1cccc(-c2cccc3cc(Cc4cc(F)cc(Cl)c4)sc23)c1 CHEMBL3298233 pEC50 29.51 nM
O=C(NCCO)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4877187 EC50 30.1 nM
COC[C@@H](O)CNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(Cl)c2)ccn1 CHEMBL4873066 EC50 31.6 nM
O=C(NCCO)c1cccc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)oc23)c1 CHEMBL3299120 pEC50 34.67 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(O)c(F)c2)ccn1 CHEMBL4871096 EC50 35.9 nM
N#CCCNC(=O)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4873264 EC50 36.3 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc(F)c(CO)c2)ccn1 CHEMBL4867455 EC50 36.5 nM
O=C(NC[C@H](O)c1cccnc1)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4855685 EC50 37.0 nM
O=C(NCCO)c1cccc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 CHEMBL3299122 pEC50 37.15 nM
O=C(NCCO)c1cccc(-c2cccc3sc(Cc4cccc(C(F)(F)F)c4)cc23)c1 CHEMBL3299121 pEC50 38.02 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cc3ccccc3o2)ccn1 CHEMBL4876570 EC50 38.7 nM
O=C(NCCO)c1cccc(-c2cccc3nn(Cc4cccc(C(F)(F)F)c4)cc23)c1 CHEMBL3299123 pEC50 38.9 nM
O=C1NCCc2c1cnn2-c1ccnc(Cc2cc(F)c(Cl)c(C(F)(F)F)c2)c1 CHEMBL5278255 pEC50 39.81 nM
COCCNC(=O)c1cccc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 CHEMBL3297811 pEC50 42.66 nM
Cn1nc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)cc1C(=O)NCCO CHEMBL4228734 EC50 45.0 nM
O=C1NCCCc2c1cnn2-c1ccnc(Cc2cc(F)cc(C(F)(F)F)c2)c1 CHEMBL5273936 pEC50 50.12 nM
NC(=O)CNC(=O)c1cccc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 CHEMBL3297810 pEC50 54.95 nM
O=C(NCC1(CO)COC1)c1c(F)ccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4871931 EC50 55.9 nM
Cc1cc(-n2cc(Cc3cc(F)cc(C(F)(F)F)c3)nc2C)ccc1C(N)=O CHEMBL4101517 EC50 59.0 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cnc3ccccc3c2)ccn1 CHEMBL4876029 EC50 61.0 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2cnc(F)c(F)c2)ccn1 CHEMBL4856067 EC50 61.6 nM
COCCNC(=O)c1cnn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1C CHEMBL4226750 EC50 62.0 nM
COCCNC(=O)c1cnn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 CHEMBL4226253 EC50 62.0 nM
O=C1NCCc2c1cnn2-c1cc(Cc2cccc(C(F)(F)F)c2)ccn1 CHEMBL5271921 pEC50 63.1 nM
O=C(NCCO)c1cccc(-c2cccc3cn(Cc4cccc(C(F)(F)F)c4)nc23)c1 CHEMBL3299124 pEC50 64.57 nM
O=C(NC[C@H](O)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4862739 EC50 72.0 nM
Cc1cc(-c2sc(Cc3cccc(C(F)(F)F)c3)nc2C)ccc1C(N)=O CHEMBL4080724 EC50 73.0 nM
Cc1cc(-n2nc(Cc3cc(F)cc(C(F)(F)F)c3)nc2C)ccc1C(N)=O CHEMBL4082756 EC50 75.0 nM
Cc1cc(Cc2cccc(C(F)(F)F)c2)cc(N2CCc3c(C(N)=O)cccc32)n1 CHEMBL4847476 EC50 80.4 nM
Cc1c(Cc2cccc(C(F)(F)F)c2)oc2c(-c3cccc(C(=O)NCCO)c3)cccc12 CHEMBL3297809 pEC50 81.28 nM
CCc1cc(-c2sc(Cc3cccc(C(F)(F)F)c3)nc2C)ccc1C(N)=O CHEMBL4099668 EC50 83.0 nM
NC(=O)CNC(=O)c1cccc(-c2ccc(F)c3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 CHEMBL3298234 pEC50 83.18 nM
O=C(NCCO)c1cnn(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 CHEMBL4226225 EC50 87.0 nM
Cc1cccc(Cc2cc(N3CCc4c(C(=O)NCCO)cccc43)ncn2)c1 CHEMBL4761381 EC50 90.0 nM
Cc1cc(C)cc(Cc2cc(N3CCc4c(C(=O)NCCO)cccc43)ncn2)c1 CHEMBL4741200 EC50 97.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Oc2cc(F)cc(C(F)(F)F)c2)ccn1 CHEMBL4874102 EC50 98.4 nM
O=C1NCCc2c1cnn2-c1cncc(Cc2cc(F)cc(C(F)(F)F)c2)c1 CHEMBL5280513 pEC50 100.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cccc(C(F)(F)F)c2)ncn1 CHEMBL4779158 EC50 101.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cccc(F)c2)ncn1 CHEMBL4762205 EC50 106.0 nM
O=C(N[C@H]1CCOC1)c1cccc2c1CCN2c1cccc(Cc2cccc(C(F)(F)F)c2)n1 CHEMBL4848041 EC50 106.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccc(C(F)(F)F)cc2)ncn1 CHEMBL4780640 EC50 109.0 nM
Cc1nc(Cc2cccc(C(F)(F)F)c2)sc1-c1ccc(C(N)=O)c(C(F)(F)F)c1 CHEMBL4073584 EC50 110.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(F)c2)ncn1 CHEMBL4755625 EC50 115.0 nM
Cc1cc(-c2sc(Cc3cccc(Cl)c3)nc2C)ccc1C(N)=O CHEMBL4095110 EC50 130.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cccc(OC(F)(F)F)c2)ncn1 CHEMBL4756386 EC50 131.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4780654 EC50 135.0 nM
O=C(N[C@@H]1CCOC1=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4877497 EC50 142.0 nM
Cc1c(C(=O)NCCO)c(CO)nn1-c1cccc2cc(Cc3cccc(C(F)(F)F)c3)sc12 CHEMBL4226751 EC50 146.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)cnn1 CHEMBL4761453 EC50 158.0 nM
COc1cccc(Cc2nc(C)c(-c3ccc(C(N)=O)c(C)c3)s2)c1 CHEMBL4081439 EC50 160.0 nM
COc1cc(-c2sc(Cc3cccc(C(F)(F)F)c3)nc2C)ccc1C(N)=O CHEMBL4062229 EC50 170.0 nM
O=C(NCCO)c1cccc2c1CCN2c1nccc(Cc2cc(F)cc(C(F)(F)F)c2)n1 CHEMBL4757616 EC50 186.0 nM
O=C(NCCO)c1cccc(-c2cccc3c2OC(Cc2cccc(C(F)(F)F)c2)C3)c1 CHEMBL3297807 pEC50 208.93 nM
Cc1cc(-c2sc(Cc3ccc(Cl)cc3)nc2C)ccc1C(N)=O CHEMBL4064577 EC50 210.0 nM
NC(=O)c1cccc2c1CCN2c1cc(Cc2ccc3c(c2)OCCCO3)ccn1 CHEMBL4862638 EC50 212.0 nM
Cc1nc(Cc2cccc(C(F)(F)F)c2)sc1-c1ccc(C(N)=O)cc1 CHEMBL4091030 EC50 220.0 nM
CNC(=O)c1cc(Cc2ccnc(N3CCc4c(C(N)=O)cccc43)c2)ccc1F CHEMBL4849975 EC50 223.0 nM
O=C1NCc2c1cnn2-c1ccnc(Cc2cc(F)cc(C(F)(F)F)c2)c1 CHEMBL5272124 pEC50 251.19 nM
Cc1cc(-c2sc(Cc3cccc(F)c3)nc2C)ccc1C(N)=O CHEMBL4070849 EC50 260.0 nM
O=C(NCCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4740473 EC50 275.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccccc2)ncn1 CHEMBL4783576 EC50 292.0 nM
O=C(NC[C@H](O)C(F)(F)F)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4847442 EC50 292.0 nM
COCC(COC)NC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)c(F)c(F)c2)ccn1 CHEMBL4850677 EC50 307.0 nM
O=C(NCCO)c1cccc2c1CCN2c1nccc(C(F)c2cc(F)cc(C(F)(F)F)c2)n1 CHEMBL4754435 EC50 329.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(C(F)c2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4797286 EC50 330.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(C(O)c2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4797830 EC50 338.0 nM
O=C(NC(CO)CO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4755614 EC50 346.0 nM
O=C(NCCO)c1cccc(-c2cccc(OCCc3cc(F)cc(Cl)c3)n2)c1 CHEMBL3299118 pEC50 346.74 nM
COc1cccc(Cc2cc(N3CCc4c(C(=O)NCCO)cccc43)ncn2)c1 CHEMBL4792434 EC50 351.0 nM
Cc1nc(Cc2cccc(C(F)(F)F)c2)sc1-c1ccc(C(N)=O)c(C(C)C)c1 CHEMBL4072782 EC50 370.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Sc2cccc(C(F)(F)F)c2)ncn1 CHEMBL4751311 EC50 371.0 nM
O=C(NCCO)c1cccc2c1CCN2c1ccnc(Cc2cc(F)cc(C(F)(F)F)c2)n1 CHEMBL4799772 EC50 373.0 nM
Cc1nc(Cc2cccc(C(F)(F)F)c2)sc1-c1ccc(C(N)=O)c(F)c1 CHEMBL4083957 EC50 380.0 nM
O=C(NCCCCO)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4754346 EC50 399.0 nM
O=C(NCCO)c1cccc2c1CCN2c1nccc(C(O)c2cc(F)cc(C(F)(F)F)c2)n1 CHEMBL4755935 EC50 399.0 nM
Cc1nc(Cc2cccc(C(F)(F)F)c2)sc1-c1ccc(C(N)=O)cn1 CHEMBL4099457 EC50 400.0 nM
NC(=O)c1cccc2c1CCN2c1cc(Sc2cccc(C(F)(F)F)c2)ccn1 CHEMBL4857044 EC50 428.0 nM
O=C(NCCF)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4741318 EC50 431.0 nM
COCCNC(=O)c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1 CHEMBL4748048 EC50 489.0 nM
O=C1NCCc2nn(-c3ccnc(Cc4cc(F)cc(C(F)(F)F)c4)c3)cc21 CHEMBL5291296 pEC50 501.19 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(C(F)c2cccc(C(F)(F)F)c2)ncn1 CHEMBL4790115 EC50 557.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(C(O)c2cccc(C(F)(F)F)c2)ncn1 CHEMBL4781520 EC50 560.0 nM
O=C(NCCO)c1cccc2c1CCN2c1nncc(Cc2cc(F)cc(C(F)(F)F)c2)c1Cl CHEMBL4757171 EC50 565.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cncc(Cc2cccc(C(F)(F)F)c2)n1 CHEMBL4867123 EC50 601.0 nM
O=C(/C=C/CCc1ccccc1)c1ccco1 CHEMBL4780703 IC50 630.0 nM
O=C(/C=C/CCc1ccccc1)c1cccs1 CHEMBL4782344 IC50 630.0 nM
O=C1NCCc2c1nnn2-c1ccnc(Cc2cc(F)cc(C(F)(F)F)c2)c1 CHEMBL5267002 pEC50 630.96 nM
O=C(NCCO)c1cccc(-c2cccc(OCCc3cccc(C(F)(F)F)c3)n2)c1 CHEMBL3299117 pEC50 645.65 nM
O=C(NCCO)c1cccc(-c2cccc3c2CC(Cc2cccc(C(F)(F)F)c2)O3)c1 CHEMBL3299125 pEC50 645.65 nM
O=C(/C=C/CCc1ccccc1)c1ccccc1 CHEMBL2375494 IC50 650.0 nM
O=C(c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1)N(CCO)CCO CHEMBL4761550 EC50 673.0 nM
Cc1cc(-c2sc(Cc3cccc(N(C)C)c3)nc2C)ccc1C(N)=O CHEMBL4091718 EC50 690.0 nM
O=C(NCCO)c1cccc2c1CCN2c1cc(Cc2ccccc2C(F)(F)F)ncn1 CHEMBL4779620 EC50 711.0 nM
Cc1c(Cc2cc(F)cc(C(F)(F)F)c2)cnnc1N1CCc2c(C(=O)NCCO)cccc21 CHEMBL4789517 EC50 754.0 nM
O=C(c1cccc2c1CCN2c1cc(Cc2cc(F)cc(C(F)(F)F)c2)ncn1)N1CC(O)C1 CHEMBL4788591 EC50 760.0 nM
COc1cc(Cc2cc(N3CCc4c(C(=O)NCCO)cccc43)ncn2)cc(OC)c1 CHEMBL4746394 EC50 850.0 nM
O=C(/C=C/CCc1ccccc1)c1ccsc1 CHEMBL4796964 IC50 910.0 nM