[O-][n+]1cc(O)cc(CCCc2ccc(Cl)c3ccccc23)c1 CHEMBL5437237 EC50 0.003 nM
[O-][n+]1cc(O)cc(CCCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 CHEMBL5404956 EC50 0.006 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(COC3CCCCC3)ccc1-2 CHEMBL3717600 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(COCC3CCCC3)ccc1-2 CHEMBL3716527 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(OCC3CCCCO3)ccc1-2 CHEMBL3716889 IC50 0.01 nM
COC(CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O)C(C)C CHEMBL3716528 IC50 0.01 nM
CC(C)(C)C(O)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3717809 IC50 0.01 nM
CC(C)(C)COCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3714785 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(OCC3CC3)ccc1-2 CHEMBL3715088 IC50 0.01 nM
CC(C)C(O)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3716159 IC50 0.01 nM
CCC(C)(C)CNc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3716561 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(CCC3CC3)ccc1-2 CHEMBL3718720 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(C#CC3CC3)ccc1-2 CHEMBL3716365 IC50 0.01 nM
CCCCCc1ccc2c(c1)CCn1c-2cc(OC[C@H]2COCCO2)nc1=O CHEMBL3714783 IC50 0.01 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(COC3CCCC3)ccc1-2 CHEMBL3716784 IC50 0.01 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(CCC3CC3)ccc1-2 CHEMBL3715907 IC50 0.01 nM
CC(C)C#Cc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3715064 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(COC3CCCC3)ccc1-2 CHEMBL3717416 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CC(O)c3cccnc3)ccc1-2 CHEMBL3717753 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CCNc3ccccc3)ccc1-2 CHEMBL3715656 IC50 0.01 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(OCc3noc(C4CC4)n3)ccc1-2 CHEMBL3717743 IC50 0.01 nM
CCCC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3717641 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(NCc3ccco3)ccc1-2 CHEMBL3718005 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CCNCc3ccccc3)ccc1-2 CHEMBL3716958 IC50 0.01 nM
CC(C)C(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3716024 IC50 0.01 nM
CC(C)CC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3717853 IC50 0.01 nM
CN(CC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O)Cc1ccccc1 CHEMBL3717201 IC50 0.01 nM
CCCCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3717795 IC50 0.01 nM
CC(C)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3714904 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CC3CCCCC3)ccc1-2 CHEMBL3715192 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CC3CCCC3)ccc1-2 CHEMBL3718497 IC50 0.01 nM
CC(C)c1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)no1 CHEMBL3719374 IC50 0.01 nM
CCc1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)no1 CHEMBL3719101 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(OCc3noc(C4CC4)n3)ccc1-2 CHEMBL3718331 IC50 0.01 nM
CC(C)(C)c1cnc(COc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)o1 CHEMBL3718192 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(OCc3ncc(-c4ccccc4)o3)ccc1-2 CHEMBL3718244 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccc(N4CCCC4)nc3)ccc1-2 CHEMBL3718528 IC50 0.01 nM
CC(C)(C)OCc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715443 IC50 0.01 nM
COc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c(OC)n1 CHEMBL3716722 IC50 0.01 nM
CCOc1ncccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3717905 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccc(N4CCCCC4)nc3)ccc1-2 CHEMBL3716728 IC50 0.01 nM
COc1ccc(OC)c(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1 CHEMBL3717963 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccc(N4CCOCC4)nc3)ccc1-2 CHEMBL3718080 IC50 0.01 nM
CCOc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3718999 IC50 0.01 nM
CC(C)Oc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3719258 IC50 0.01 nM
CC(C)(C)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715923 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#Cc3ccccn3)ccc1-2 CHEMBL3718350 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CC3CC3)ccc1-2 CHEMBL3719092 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(CCc3ccccn3)ccc1-2 CHEMBL3716446 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(OCc3ccccn3)ccc1-2 CHEMBL3719364 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(COCC3CC3)ccc1-2 CHEMBL3715817 IC50 0.01 nM
COC(C)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3719100 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(CCCNc3ccccc3)ccc1-2 CHEMBL3716280 IC50 0.01 nM
CCC(O)(CC)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3719080 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(OCC3CCOCC3)ccc1-2 CHEMBL3717790 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(OCC3COC3)ccc1-2 CHEMBL3716123 IC50 0.01 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(OCCCC3CC3)ccc1-2 CHEMBL3714806 IC50 0.01 nM
COCCCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718618 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(CCC3(O)CCCC3)ccc1-2 CHEMBL3719143 IC50 0.01 nM
CCCOCCOc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3717755 IC50 0.01 nM
CC(C)OCCOc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3717086 IC50 0.01 nM
COCCCCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3716184 IC50 0.01 nM
CC(C)(C)c1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)no1 CHEMBL3715322 IC50 0.01 nM
CCCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715514 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccc4[nH]ccc4c3)ccc1-2 CHEMBL3718280 IC50 0.01 nM
Cn1ccc2cc(-c3ccc4c(c3)CCn3c-4cc(OCC4COCCO4)nc3=O)ccc21 CHEMBL3717390 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#Cc3cccnc3)ccc1-2 CHEMBL3717158 IC50 0.01 nM
COc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1OC CHEMBL3717251 IC50 0.01 nM
CCC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3717453 IC50 0.01 nM
CC(O)(C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O)c1ccccc1 CHEMBL3714875 IC50 0.01 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(C#CC3CC3)ccc1-2 CHEMBL3717363 IC50 0.01 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(CCC(O)c3cccnc3)ccc1-2 CHEMBL3715055 IC50 0.01 nM
COCCOCC#Cc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718818 IC50 0.01 nM
CC(O)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718174 IC50 0.01 nM
CC(O)CCCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718719 IC50 0.01 nM
CC(C)(C)COc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3715679 IC50 0.01 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(COCC3CCOCC3)ccc1-2 CHEMBL3715918 IC50 0.01 nM
COCCCc1ccc2c(c1)CCn1c-2cc(OC[C@H]2COCCO2)nc1=O CHEMBL3717924 IC50 0.01 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(CCC3(O)CCCC3)ccc1-2 CHEMBL3714986 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CCCO)ccc1-2 CHEMBL3715466 IC50 0.01 nM
Cc1cc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)nn1C CHEMBL3717888 IC50 0.01 nM
Cc1noc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)n1 CHEMBL3718310 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#Cc3ccncc3)ccc1-2 CHEMBL3718068 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CCO)ccc1-2 CHEMBL3716912 IC50 0.01 nM
Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3718542 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CC3(O)CCCC3)ccc1-2 CHEMBL3719234 IC50 0.01 nM
N#CCCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715145 IC50 0.01 nM
CC(C)(C)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715561 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOc3ccccc3)ccc1-2 CHEMBL3719036 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCC3COc4ccccc4O3)ccc1-2 CHEMBL3714958 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc([N+](=O)[O-])c3)ccc1-2 CHEMBL3718388 IC50 0.01 nM
NC(=O)c1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)c1 CHEMBL3715263 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3cncnc3)ccc1-2 CHEMBL3718025 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3ccc4[nH]ncc4c3)ccc1-2 CHEMBL3717155 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3cccnc3)ccc1-2 CHEMBL3717964 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCc3ccncc3)ccc1-2 CHEMBL3719180 IC50 0.01 nM
COc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3715970 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(-c3ccc4ccccc4c3)ccc1-2 CHEMBL3718872 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(COC3COC3)ccc1-2 CHEMBL3718246 IC50 0.01 nM
CC1(COCc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)COC1 CHEMBL3715069 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(CN3CCCCC3)ccc1-2 CHEMBL3719012 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CCNc3ccccc3)ccc1-2 CHEMBL3715684 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CCNCc3ccccc3)ccc1-2 CHEMBL3718687 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(COCCN3CCOCC3)ccc1-2 CHEMBL3717323 IC50 0.01 nM
O=c1nc(OC[C@H]2COc3ncccc3O2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 CHEMBL3714891 IC50 0.01 nM
CC(C)C(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3718693 IC50 0.01 nM
CC(O)(C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O)c1ccccc1 CHEMBL3719248 IC50 0.01 nM
CCC(O)(C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O)CC CHEMBL3715779 IC50 0.01 nM
CC(C)CC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715016 IC50 0.01 nM
CCCC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3718814 IC50 0.01 nM
CCC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3716828 IC50 0.01 nM
CC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3719339 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3cn[nH]c3)ccc1-2 CHEMBL3718482 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCC3CCCCO3)ccc1-2 CHEMBL3717805 IC50 0.01 nM
NC(=O)NCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3716815 IC50 0.01 nM
CN(C)CC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3718203 IC50 0.01 nM
N#CCCOCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715307 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CC(O)c3ccccc3)ccc1-2 CHEMBL3718309 IC50 0.01 nM
COc1ccc(OC)c(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)c1 CHEMBL3716622 IC50 0.01 nM
COc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)c1OC CHEMBL3716443 IC50 0.01 nM
COc1ncc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3719011 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3ccc(N4CCOCC4)nc3)ccc1-2 CHEMBL3718169 IC50 0.01 nM
CCOc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3715943 IC50 0.01 nM
CCOc1ncccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3717010 IC50 0.01 nM
N#Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3715639 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C3=CCOCC3)ccc1-2 CHEMBL3717958 IC50 0.01 nM
COc1nccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)c1Cl CHEMBL3718281 IC50 0.01 nM
Cc1cc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)on1 CHEMBL3714918 IC50 0.01 nM
CC(C)(C)c1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)no1 CHEMBL3715645 IC50 0.01 nM
CC(C)c1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)no1 CHEMBL3716930 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCc3noc(C4CC4)n3)ccc1-2 CHEMBL3717081 IC50 0.01 nM
CCc1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)no1 CHEMBL3718294 IC50 0.01 nM
Cc1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)no1 CHEMBL3718050 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(NCc3ncco3)ccc1-2 CHEMBL3717255 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(CN3CCOCC3)ccc1-2 CHEMBL3718521 IC50 0.01 nM
Cn1cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3716178 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3ccoc3)ccc1-2 CHEMBL3716242 IC50 0.01 nM
CNC(=O)c1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 CHEMBL3718580 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1ccccc1-2 CHEMBL3717782 IC50 0.01 nM
COc1ncccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3717267 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CC3CC3)ccc1-2 CHEMBL3718614 IC50 0.01 nM
COc1cncc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)c1 CHEMBL3719065 IC50 0.01 nM
CC(C)(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715691 IC50 0.01 nM
N#Cc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)c1 CHEMBL3718808 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3ccncc3)ccc1-2 CHEMBL3717169 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCc3nnn[nH]3)ccc1-2 CHEMBL3719334 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCc3ccccn3)ccc1-2 CHEMBL3716925 IC50 0.01 nM
N#CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715646 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3noc(-c4ccccc4)n3)ccc1-2 CHEMBL3716202 IC50 0.01 nM
CC(C)(C)c1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)no1 CHEMBL3719047 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 CHEMBL3718963 IC50 0.01 nM
CCOC(=O)c1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ccccc4O3)nc2=O)o1 CHEMBL3715990 IC50 0.01 nM
O=C(COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O)NCc1ccccc1 CHEMBL3715925 IC50 0.01 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCc3nnn[nH]3)ccc1-2 CHEMBL3719052 IC50 0.01 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCc3nnnn3C3CC3)ccc1-2 CHEMBL3717472 IC50 0.01 nM
N#CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3718064 IC50 0.01 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCCN3CCOCC3)ccc1-2 CHEMBL3718258 IC50 0.01 nM
CCCCn1nnnc1NC(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3716438 IC50 0.01 nM
CCCn1nnnc1NC(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3715985 IC50 0.01 nM
O=C(COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O)Nc1ccccc1 CHEMBL3716399 IC50 0.01 nM
CC(C)N(C)C(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3717326 IC50 0.01 nM
O=C(COc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O)Nc1ccccc1 CHEMBL3718511 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc(-c4ccoc4)n3)ccc1-2 CHEMBL3717729 IC50 0.01 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCC3CCCO3)ccc1-2 CHEMBL3716761 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOCc3ccccc3)ccc1-2 CHEMBL3718543 IC50 0.01 nM
CC(C)(Oc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O)C(N)=O CHEMBL3717695 IC50 0.01 nM
CN(C)C(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3716369 IC50 0.01 nM
NC(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3719276 IC50 0.01 nM
O=C(COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O)N1CCOCC1 CHEMBL3718620 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOc3ccc(Cl)cc3)ccc1-2 CHEMBL3717664 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOc3cccc(Cl)c3)ccc1-2 CHEMBL3715290 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOc3ccccc3Cl)ccc1-2 CHEMBL3718767 IC50 0.01 nM
COc1ccc(OCCOc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3719113 IC50 0.01 nM
COc1cccc(OCCOc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3715513 IC50 0.01 nM
COc1ccccc1OCCOc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3716125 IC50 0.01 nM
Cc1ccccc1COc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3715227 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccc4ccccc4c3)ccc1-2 CHEMBL3717594 IC50 0.01 nM
COc1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3716251 IC50 0.01 nM
Cc1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3717786 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccc([N+](=O)[O-])cc3)ccc1-2 CHEMBL3717358 IC50 0.01 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCC3COc4ccccc4O3)ccc1-2 CHEMBL3715436 IC50 0.01 nM
CC(C)(C)OC(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3716166 IC50 0.01 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCc3ccccn3)ccc1-2 CHEMBL3718158 IC50 0.01 nM
COC(=O)c1cccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3716311 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccccc3[N+](=O)[O-])ccc1-2 CHEMBL3715210 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc(Cl)c3)ccc1-2 CHEMBL3718642 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccc(Cl)cc3)ccc1-2 CHEMBL3717318 IC50 0.01 nM
N#Cc1ccccc1COc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3716734 IC50 0.01 nM
N#Cc1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3716482 IC50 0.01 nM
COc1ccc2c(c1)CCn1c-2cc(OCC2CCCCO2)nc1=O CHEMBL3716185 IC50 0.01 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccccc3)ccc1-2 CHEMBL3718668 IC50 0.01 nM
COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3714917 IC50 0.01 nM
O=C(COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O)N1CCCC1 CHEMBL3719089 IC50 0.01 nM
O=c1nc(OC[C@@H]2COc3ncccc3O2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 CHEMBL3717676 IC50 0.01 nM
N#Cc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3717108 IC50 0.01 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#Cc3cccnc3)ccc1-2 CHEMBL3715503 IC50 0.01 nM
COCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3716520 IC50 0.01 nM
[O-][n+]1cc(O)cc(CCCc2ccc(Cl)c(C(F)(F)F)c2)c1 CHEMBL5395893 pEC50 0.01862 nM
CCCCCCCCCc1cc(O)cc(O)n1 CHEMBL3828298 EC50 0.189 nM
CCCCCCSc1nc(O)cc(O)n1 CHEMBL3827756 Ki 0.219 nM
[3H]c1cccc(CCc2ccc3c(c2)CCn2c-3cc(OCCOc3cnccn3)nc2=O)c1 CHEMBL4742704 Kd 0.24 nM
O=c1cc(NCCc2ccc(Br)cc2)[nH]c(=O)[nH]1 CHEMBL4444010 Ki 0.317 nM
Oc1cc(O)nc(SCCCCc2ccccc2)n1 CHEMBL3827310 Ki 0.324 nM
Oc1cc(NCCCCc2ccccc2)nc(O)n1 CHEMBL88536 Ki 0.58 nM
CCc1ccc(CCNc2cc(=O)[nH]c(=O)[nH]2)cc1 CHEMBL4547165 Ki 0.582 nM
CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1 CHEMBL3827832 Ki 0.626 nM
O=c1cc(NCCc2ccc(Cl)cc2)[nH]c(=O)[nH]1 CHEMBL4538049 Ki 0.65 nM
Oc1cc(O)nc(SCCCc2ccccc2)n1 CHEMBL3828415 Ki 0.7 nM
CCCCCCCCCCNc1cc(O)nc(O)n1 CHEMBL125436 Ki 0.726 nM
CCCCCCCNc1cc(=O)[nH]c(=O)[nH]1 CHEMBL4468895 Ki 0.866 nM
CCCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1 CHEMBL4521587 Ki 1.12 nM
Cc1ccc(CCNc2cc(=O)[nH]c(=O)[nH]2)cc1 CHEMBL4439640 Ki 1.25 nM
CCCCCCCc1cc(O)cc(O)n1 CHEMBL13302 EC50 1.26 nM
CC(C)(C)c1ccc(CCNc2cc(=O)[nH]c(=O)[nH]2)cc1 CHEMBL4580884 Ki 1.27 nM
CCCCCCCCc1cc(O)cc(O)n1 CHEMBL3827638 EC50 1.34 nM
CCCCCCCCC1=C(O)C(=O)C=C(O)C1=O CHEMBL221598 EC50 1.6 nM
O=c1cc(NCCCOc2ccccc2)[nH]c(=O)[nH]1 CHEMBL4528940 Ki 2.1 nM
O=c1cc(NCCc2ccc(Cl)cc2Cl)[nH]c(=O)[nH]1 CHEMBL4571353 Ki 2.3 nM
O=c1cc(O)nc(SCCc2ccc(Cl)cc2)[nH]1 CHEMBL4438595 Ki 2.63 nM
CCCCCCNc1cc(O)nc(O)n1 CHEMBL124977 Ki 2.98 nM
O=c1cc(NCCOc2ccccc2)[nH]c(=O)[nH]1 CHEMBL4528577 Ki 3.12 nM
O=c1cc(O)nc(SCCc2ccc(Br)cc2)[nH]1 CHEMBL4562761 Ki 3.17 nM
Cc1ccc(CCSc2nc(O)cc(=O)[nH]2)cc1 CHEMBL4534827 Ki 3.28 nM
CCCCCCCCN(C)c1cc(=O)[nH]c(=O)[nH]1 CHEMBL4568775 Ki 3.6 nM
O=c1cc(O)nc(SCCc2ccc(F)cc2)[nH]1 CHEMBL4467630 Ki 3.77 nM
O=c1cc(NCCc2cccc(Br)c2)[nH]c(=O)[nH]1 CHEMBL4468678 Ki 3.99 nM
COc1cccc2c1Sc1cccc(F)c1C=C2OP(=O)([O-])OC1=Cc2c(F)cccc2Sc2c(OC)cccc21 CHEMBL5205352 IC50 4.58 nM
c1ccc(-c2nc(Cc3c[nH]c4cnccc34)nnc2-c2ccc(CN3CCOCC3)cc2)cc1 CHEMBL5170226 pIC50 4.677 nM
O=c1cc(NCCc2cccc(Cl)c2)[nH]c(=O)[nH]1 CHEMBL4473999 Ki 4.75 nM
O=c1nc(OCCOc2cnccn2)cc2n1CCc1cc(CCc3ccccc3)ccc1-2 CHEMBL4794652 IC50 5.0 nM
CC(=O)OCc1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5186088 pIC50 5.012 nM
c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccc(CN3CCOCC3)cc2)cc1 CHEMBL5180818 pIC50 5.248 nM
CCCCCCCCNc1nc(O)cc(O)n1 CHEMBL3828303 EC50 6.14 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5191944 IC50 6.67 nM
CCCCCCN(C)c1cc(=O)[nH]c(=O)[nH]1 CHEMBL4451909 Ki 6.94 nM
c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5171669 pIC50 7.244 nM
COc1cc2c(cc1OC)-c1cc(OCCOc3ccccn3)nc(=O)n1CC2 CHEMBL4776061 IC50 8.0 nM
c1ccc(-c2nnc(Cc3c[nH]c4cnccc34)nc2-c2ccccc2)cc1 CHEMBL5207823 pIC50 8.511 nM
[O-][n+]1cccc(CCCc2ccc(Cl)c3ccccc23)c1 CHEMBL5411044 pEC50 8.511 nM
CC(=O)OCc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5172567 pIC50 8.71 nM
O=P([O-])(OC1=Cc2c(Cl)cccc2Sc2ccccc21)OC1=Cc2c(Cl)cccc2Sc2ccccc21 CHEMBL5179395 IC50 8.95 nM
COc1cccc2c1Sc1cc(F)ccc1C=C2OP(=O)([O-])OC1=Cc2ccc(F)cc2Sc2c(OC)cccc21 CHEMBL5176994 IC50 9.36 nM
O=c1cc(NCCc2cccc(F)c2)[nH]c(=O)[nH]1 CHEMBL4474487 Ki 9.48 nM
CNC(=O)c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5172502 pIC50 9.772 nM
O=c1cc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3cccnc3)ccc1-2 CHEMBL4085616 IC50 10.0 nM
O=c1cc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3ccc4[nH]ncc4c3)ccc1-2 CHEMBL4103552 IC50 10.0 nM
NC(=O)c1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)cc2=O)c1 CHEMBL4082477 IC50 10.0 nM
O=c1cc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#Cc3ccncn3)ccc1-2 CHEMBL4060589 IC50 10.0 nM
O=c1cc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CCCO)ccc1-2 CHEMBL4090321 IC50 10.0 nM
Cc1cc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)cc2=O)nn1C CHEMBL4069275 IC50 10.0 nM
Cc1noc(COc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)cc2=O)n1 CHEMBL4098028 IC50 10.0 nM
O=c1cc(OCC2COc3ncccc3O2)cc2n1CCc1cc(-c3cncnc3)ccc1-2 CHEMBL4080004 IC50 10.0 nM
CC(=O)NCc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5181240 pIC50 10.47 nM
Oc1cc(NCCc2ccccc2)nc(O)n1 CHEMBL314575 Ki 10.8 nM
CCCCCCCCc1nc(O)cc(O)n1 CHEMBL3827580 EC50 11.4 nM
O=c1cc(NCCc2ccc(F)cc2)[nH]c(=O)[nH]1 CHEMBL4565153 Ki 11.4 nM
O=P([O-])(OC1=Cc2ccccc2Cc2ccccc21)OC1=Cc2ccccc2Cc2ccccc21 CHEMBL5206571 IC50 11.4 nM
COc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccc(OC)cc2)cc1 CHEMBL5180892 pIC50 11.75 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@@H]1OP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC(F)(F)F)cccc21 CHEMBL5413740 IC50 12.0 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c3ccccc23)c1 CHEMBL4743442 pEC50 12.3 nM
CCCCCCCc1nc(O)cc(O)n1 CHEMBL3828708 EC50 12.7 nM
O=c1cccc(CCOc2ccc(Cl)c3ccccc23)[nH]1 CHEMBL5394311 pEC50 12.88 nM
O=c1cc(N2CCN(C3CCc4ccccc43)CC2)[nH]c(=O)[nH]1 CHEMBL4575870 Ki 14.7 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@@H]1C(C)(C)[C@@H]2CC[C@@]1(C)C2 CHEMBL5411648 IC50 15.0 nM
Fc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccc(F)cc2)cc1 CHEMBL5204521 pIC50 15.49 nM
c1ccc(-c2nnc(Cc3c[nH]c4ccncc34)nc2-c2ccccc2)cc1 CHEMBL5186601 pIC50 16.6 nM
OCc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5191540 pIC50 17.38 nM
[O-][n+]1cc(F)cc(CCOc2ccc(Cl)c3ccccc23)c1 CHEMBL5394821 pEC50 17.78 nM
COc1ccc2c(c1)Sc1c(OC)cccc1C(OP(=O)([O-])OC1=Cc3ccc(OC)cc3Sc3c(OC)cccc31)=C2 CHEMBL5197375 IC50 18.0 nM
O=c1cc(N2CCC(Cc3ccccc3)CC2)[nH]c(=O)[nH]1 CHEMBL4517538 Ki 18.7 nM
Clc1ccccc1-c1nnc(Cc2c[nH]c3ccccc23)nc1-c1ccccc1Cl CHEMBL5191278 pIC50 19.05 nM
COc1cccc2c1Sc1ccc(F)cc1C=C2OP(=O)([O-])OC1=Cc2cc(F)ccc2Sc2c(OC)cccc21 CHEMBL5190809 IC50 19.3 nM
COCCNC(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5192235 pIC50 20.42 nM
CCCCCCOc1cc2n(c(=O)n1)CCc1cc(OC)c(OC)cc1-2 CHEMBL4750532 IC50 21.0 nM
COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL4755764 IC50 22.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])Oc1cc2ccccc2c2ccccc12 CHEMBL5433078 IC50 23.0 nM
CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O CHEMBL221137 Ki 23.6 nM
c1csc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2cccs2)c1 CHEMBL5188586 pIC50 23.99 nM
CS(=O)(=O)NCc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5183982 pIC50 24.55 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@H]1C(C)(C)[C@H]2CC[C@]1(C)C2 CHEMBL5395660 IC50 25.0 nM
Brc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccc(Br)cc2)cc1 CHEMBL5206221 pIC50 25.12 nM
COc1ccc2c(c1)Sc1ccccc1C=C2OP(=O)([O-])OC1=Cc2ccccc2Sc2cc(OC)ccc21 CHEMBL5202207 IC50 25.2 nM
O=P([O-])(OC1=Cc2c(F)cccc2Sc2ccccc21)OC1=Cc2c(F)cccc2Sc2ccccc21 CHEMBL5170437 IC50 26.2 nM
[O-][n+]1cccc(CCOc2ccc(Br)c3ccccc23)c1 CHEMBL5419003 pEC50 28.18 nM
c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccc(CN3CCOCC3)cc2)cc1 CHEMBL5180699 pIC50 30.9 nM
COc1cccc2c1Sc1c(F)cccc1C=C2OP(=O)([O-])OC1=Cc2cccc(F)c2Sc2c(OC)cccc21 CHEMBL5201979 IC50 32.3 nM
O=P(O)(OC1=Cc2ccccc2Sc2ccccc21)OC1=Cc2ccccc2Sc2ccccc21 CHEMBL5201755 IC50 33.2 nM
O=C(NCCO)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5194648 pIC50 34.67 nM
CCCCCCCCNc1[nH]c(=O)[nH]c(=O)c1Br CHEMBL4566117 Ki 34.7 nM
O=c1cc(NCCc2ccccc2F)[nH]c(=O)[nH]1 CHEMBL4449633 Ki 35.6 nM
COc1ccc2c(c1)C(OP(=O)([O-])OC1=Cc3ccccc3Sc3ccc(OC)cc31)=Cc1ccccc1S2 CHEMBL5171959 IC50 35.7 nM
O=c1cc(NCCc2ccccc2Cl)[nH]c(=O)[nH]1 CHEMBL4534071 Ki 36.0 nM
O=c1cc(O)nc(SCCc2ccc(C(F)(F)F)cc2)[nH]1 CHEMBL4574495 Ki 36.7 nM
CCCCCCCCNc1[nH]c(=O)[nH]c(=O)c1N=O CHEMBL4462370 Ki 37.0 nM
CCC/C=C/CNc1cc(=O)[nH]c(=O)[nH]1 CHEMBL4541166 Ki 37.4 nM
Cc1ccc2c(c1)Sc1ccccc1C=C2OP(=O)([O-])OC1=Cc2ccccc2Sc2cc(C)ccc21 CHEMBL5192281 IC50 38.4 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@@H]1C[C@@H]2CC[C@@]1(C)C2(C)C CHEMBL5428552 IC50 41.0 nM
Fc1cc(F)c2[nH]cc(Cc3c[nH]c4c(F)cc(F)cc34)c2c1 CHEMBL4088884 EC50 41.3 nM
O=P([O-])(OC1=Cc2cc(F)ccc2Sc2ccccc21)OC1=Cc2cc(F)ccc2Sc2ccccc21 CHEMBL5195150 IC50 41.4 nM
COC(=O)c1ccc(-c2nc(Cc3c[nH]c4cnccc34)nnc2-c2ccccc2)cc1 CHEMBL5201371 pIC50 42.66 nM
O=c1cc(N2CCN(c3ccc(Cl)cc3)CC2)[nH]c(=O)[nH]1 CHEMBL4584001 Ki 44.4 nM
O=P([O-])(OC1=Cc2ccccc2C2(CC2)c2ccccc21)OC1=Cc2ccccc2C2(CC2)c2ccccc21 CHEMBL5183789 IC50 45.2 nM
CCOc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC1=Cc2ccccc2Sc2c(OCC)cccc21 CHEMBL5198754 IC50 46.1 nM
CCCCCCCCCc1nc(O)cc(O)n1 CHEMBL3827526 EC50 48.7 nM
COC(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5194322 pIC50 48.98 nM
O=c1cc(NCCc2cccs2)[nH]c(=O)[nH]1 CHEMBL4466657 Ki 49.4 nM
CNC(=O)c1ccc(-c2nnc(Cc3c[nH]c4cnccc34)nc2-c2ccccc2)cc1 CHEMBL5187543 pIC50 51.29 nM
Fc1cc2[nH]cc(Cc3c[nH]c4cc(F)c(F)cc34)c2cc1F CHEMBL4078546 EC50 52.4 nM
c1ccc(-c2nnc(Cc3c[nH]c4cnccc34)nc2-c2ccc(CN3CCOCC3)cc2)cc1 CHEMBL5189536 pIC50 53.7 nM
COc1ccc2c(c1)C=C(OP(=O)([O-])OC1=Cc3cc(OC)ccc3Sc3c(OC)cccc31)c1cccc(OC)c1S2 CHEMBL5175363 IC50 55.6 nM
COc1cc(CCCc2ccc(Cl)c3ccccc23)c[n+]([O-])c1 CHEMBL5416844 pEC50 56.23 nM
CCCCCCCNc1[nH]c(=O)[nH]c(=O)c1N=O CHEMBL4574715 Ki 58.6 nM
Brc1ccc2[nH]cc(Cc3c[nH]c4ccc(Br)cc34)c2c1 CHEMBL246504 EC50 59.1 nM
Fc1cccc2c(Cc3c[nH]c4c(F)cccc34)c[nH]c12 CHEMBL4062512 EC50 61.8 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@H]1C[C@@H]2CC[C@@]1(C)C2(C)C CHEMBL5416118 IC50 62.0 nM
[O-][n+]1cccc(CCOc2ccc(F)c3ccccc23)c1 CHEMBL5436093 EC50 62.6 nM
O=c1cc(N2CCN(Cc3cccc4ccccc34)CC2)[nH]c(=O)[nH]1 CHEMBL4459188 Ki 62.7 nM
COc1cc2c(cc1OC)-c1cc(OCCOc3ccccc3)nc(=O)n1CC2 CHEMBL4756307 IC50 63.0 nM
O=C(c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1)N1CCOCC1 CHEMBL5185972 pIC50 64.57 nM
Cc1ccc2c(c1)C(OP(=O)([O-])OC1=Cc3ccccc3Sc3ccc(C)cc31)=Cc1ccccc1S2 CHEMBL5192624 IC50 65.3 nM
CNC(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5199559 pIC50 66.07 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@@H]1C[C@H](C)CC[C@H]1C(C)C CHEMBL5400040 IC50 68.0 nM
OCc1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5180745 pIC50 69.18 nM
O=P([O-])(OC1=Cc2ccccc2Sc2ccccc21)OC1=Cc2ccccc2Sc2ccccc21 CHEMBL5194984 IC50 74.0 nM
Cc1ccc(CCOc2ccc(Cl)c3ccccc23)c[n+]1[O-] CHEMBL5419327 pEC50 75.86 nM
Fc1ccc2[nH]cc(Cc3c[nH]c4ccc(F)cc34)c2c1 CHEMBL4101728 EC50 80.0 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c(I)c2)c1 CHEMBL5416693 EC50 82.8 nM
Fc1ccc2[nH]cc(Cc3c[nH]c4ccc(F)c(F)c34)c2c1F CHEMBL4096571 EC50 83.6 nM
O=C(O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5183310 pIC50 87.1 nM
CCc1ccc(CCc2nc(O)cc(O)n2)cc1 CHEMBL3828073 EC50 88.1 nM
O=P([O-])(OC1=Cc2cc(Cl)ccc2Sc2ccccc21)OC1=Cc2cc(Cl)ccc2Sc2ccccc21 CHEMBL5187339 IC50 88.5 nM
Cc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC1=Cc2ccccc2Sc2c(C)cccc21 CHEMBL5177531 IC50 89.0 nM
CCCCCNc1cc(O)nc(O)n1 CHEMBL124310 Ki 91.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@H]1C[C@@H](C)CC[C@@H]1C(C)C CHEMBL5407283 IC50 91.0 nM
O=C(NCCO)c1ccc(-c2nnc(Cc3c[nH]c4cnccc34)nc2-c2ccccc2)cc1 CHEMBL5198225 pIC50 91.2 nM
COC(=O)c1ccc(-c2nnc(Cc3c[nH]c4cnccc34)nc2-c2ccccc2)cc1 CHEMBL5205398 pIC50 95.5 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c(C3CC3)c2)c1 CHEMBL5426206 EC50 99.4 nM
N#Cc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3718710 IC50 100.0 nM
CN(C)c1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3717592 IC50 100.0 nM
COc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3718718 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(C#CC3CC3)ccc1-2 CHEMBL3718569 IC50 100.0 nM
Cc1noc(C)c1-c1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3715983 IC50 100.0 nM
COc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cn1 CHEMBL3715761 IC50 100.0 nM
Cc1cccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3719274 IC50 100.0 nM
CCNC1(C#Cc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)COC1 CHEMBL3717999 IC50 100.0 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(CN3CCCC3)ccc1-2 CHEMBL3715250 IC50 100.0 nM
O=C(NC1CCOCC1)c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3717979 IC50 100.0 nM
CCCCNCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3715903 IC50 100.0 nM
NC1(C#Cc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)CCCCC1 CHEMBL3715550 IC50 100.0 nM
CC(C)(N)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3714820 IC50 100.0 nM
CCN(CC)CC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3718037 IC50 100.0 nM
O=C1CN(CC#Cc2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)C(=O)N1 CHEMBL3717345 IC50 100.0 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(C#CCN3CCS(=O)(=O)CC3)ccc1-2 CHEMBL3715633 IC50 100.0 nM
CN(CC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O)Cc1ccccc1 CHEMBL3719006 IC50 100.0 nM
N#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3714825 IC50 100.0 nM
N#CCNc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3718644 IC50 100.0 nM
NC(=O)c1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3716183 IC50 100.0 nM
CN(C)c1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3718308 IC50 100.0 nM
COc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3716060 IC50 100.0 nM
COc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3718616 IC50 100.0 nM
COc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3715368 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(-c3ccccc3)ccc1-2 CHEMBL3718652 IC50 100.0 nM
N#Cc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3718615 IC50 100.0 nM
CN1CCCC1CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3714922 IC50 100.0 nM
O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(OCCN3CCOCC3)ccc1-2 CHEMBL3718109 IC50 100.0 nM
CN1CCN(CCCOc2ccc3c(c2)CCn2c-3cc(OCC3COc4ccccc4O3)nc2=O)CC1 CHEMBL3718572 IC50 100.0 nM
CN1CCCC1CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3718190 IC50 100.0 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCCCN3CCCCC3)ccc1-2 CHEMBL3716781 IC50 100.0 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCCN3CCCCC3)ccc1-2 CHEMBL3714804 IC50 100.0 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCCN3CCCC3)ccc1-2 CHEMBL3716334 IC50 100.0 nM
C=CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3716875 IC50 100.0 nM
O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 CHEMBL3718000 IC50 100.0 nM
CCN(CC)C(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3714809 IC50 100.0 nM
CCCn1nnnc1COc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3716807 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3nnnn3C3CC3)ccc1-2 CHEMBL3715120 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc(-c4cncnc4)n3)ccc1-2 CHEMBL3714897 IC50 100.0 nM
Cn1cc(-c2cccc(COc3ccc4c(c3)CCn3c-4cc(OCC4CCCO4)nc3=O)n2)cn1 CHEMBL3718451 IC50 100.0 nM
O=C(O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3717307 IC50 100.0 nM
COC(=O)c1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 CHEMBL3715086 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccc(F)cc3)ccc1-2 CHEMBL3714952 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccccc3Cl)ccc1-2 CHEMBL3716448 IC50 100.0 nM
N#Cc1cccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3716270 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccccn3)ccc1-2 CHEMBL3718778 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ccncc3)ccc1-2 CHEMBL3719373 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCc3ccccc3)ccc1-2 CHEMBL3715772 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCC3CC3)ccc1-2 CHEMBL3718406 IC50 100.0 nM
CCCCOc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3717237 IC50 100.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccnc3)ccc1-2 CHEMBL3718257 IC50 100.0 nM
CC(C)(C)CCCOc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3716619 IC50 101.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(NC3CCCCC3)ccc1-2 CHEMBL3717133 IC50 101.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(C#CCOCCF)ccc1-2 CHEMBL3715080 IC50 101.0 nM
CCOCCOCC#Cc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3716433 IC50 101.0 nM
CCOCCOc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3717561 IC50 101.0 nM
COCCOc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718802 IC50 101.0 nM
CCCCC(CC)CNc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3715870 IC50 101.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(COC3COC3)ccc1-2 CHEMBL3717016 IC50 101.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CCNCc3cccnc3)ccc1-2 CHEMBL3717471 IC50 101.0 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(COC3CCOCC3)ccc1-2 CHEMBL3718828 IC50 101.0 nM
C=CCOc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718413 IC50 101.0 nM
C=CCOc1ccc2c(c1)CCn1c-2cc(OC[C@H]2COCCO2)nc1=O CHEMBL3718289 IC50 101.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CCn3ccnc3)ccc1-2 CHEMBL3718332 IC50 101.0 nM
COC(C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O)C(C)C CHEMBL3716857 IC50 101.0 nM
C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3716050 IC50 101.0 nM
N#Cc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3717796 IC50 101.0 nM
N#Cc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OC[C@H]2COCCO2)nc1=O CHEMBL3718680 IC50 101.0 nM
CCCn1cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3717473 IC50 101.0 nM
Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)o1 CHEMBL3715594 IC50 101.0 nM
CC(C)CCn1cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3714813 IC50 101.0 nM
CCC(O)(C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O)CC CHEMBL3718036 IC50 101.0 nM
CC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3717415 IC50 101.0 nM
Cc1nc(COc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)no1 CHEMBL3717983 IC50 101.0 nM
N#Cc1ccncc1-c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3719137 IC50 101.0 nM
COc1nccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1Cl CHEMBL3719358 IC50 101.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C3=CCOCC3)ccc1-2 CHEMBL3718288 IC50 101.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1ccccc1-2 CHEMBL3715879 IC50 101.0 nM
COc1ncccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3718113 IC50 101.0 nM
Cc1cc(COc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)on1 CHEMBL3718290 IC50 101.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#Cc3ccncc3)ccc1-2 CHEMBL3714827 IC50 101.0 nM
NC(=O)c1cc(F)cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1 CHEMBL3716195 IC50 101.0 nM
NC(=O)c1ccc(F)c(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1 CHEMBL3716882 IC50 101.0 nM
COc1cccc(C#Cc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1 CHEMBL3716121 IC50 101.0 nM
CNC(=O)c1ccc(C#Cc2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cc1 CHEMBL3715009 IC50 101.0 nM
Cn1cncc1C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715095 IC50 101.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 CHEMBL3718012 IC50 101.0 nM
N#CCOc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715459 IC50 101.0 nM
N#Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cc1 CHEMBL3717967 IC50 101.0 nM
C=CCOc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715404 IC50 101.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(CCCCO)ccc1-2 CHEMBL3715690 IC50 101.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(NCC3CCCCC3)ccc1-2 CHEMBL3715540 IC50 101.0 nM
CC(C)(O)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3718393 IC50 101.0 nM
CCC(O)CCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3715265 IC50 101.0 nM
CC(C)(O)CCCc1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O CHEMBL3716157 IC50 101.0 nM
COc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3718436 IC50 101.0 nM
CCCOCCOc1ccc2c(c1)CCn1c-2cc(OC[C@H]2COCCO2)nc1=O CHEMBL3717285 IC50 101.0 nM
COc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O CHEMBL3715719 IC50 101.0 nM
Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3717653 IC50 101.0 nM
COc1ccc2[nH]cc(Cc3c[nH]c4ccc(OC)cc34)c2c1 CHEMBL246298 EC50 103.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C3CC3)ccc1-2 CHEMBL4744625 IC50 107.0 nM
CCCCCCCCCCC(=O)O CHEMBL108030 Ki 108.0 nM
CCCCCCCCOP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5429540 IC50 108.0 nM
CCCCCCCCCC(O)CC(=O)O CHEMBL4288936 Ki 110.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC1C(C)(C)CCCC1(C)C CHEMBL5394910 IC50 110.0 nM
O=P([O-])(OC1=Cc2ccc(Cl)cc2Sc2ccccc21)OC1=Cc2ccc(Cl)cc2Sc2ccccc21 CHEMBL5196560 IC50 114.0 nM
COC(=O)c1cccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)c1 CHEMBL5201724 pIC50 114.82 nM
CC(=O)NCc1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5174990 pIC50 117.49 nM
COc1ccc(-c2nnc(Cc3c[nH]c4ccc(F)cc34)nc2-c2ccc(OC)cc2)cc1 CHEMBL5179431 pIC50 120.23 nM
c1ccc(-c2nnc(Cc3c[nH]c4ncccc34)nc2-c2ccccc2)cc1 CHEMBL5195409 pIC50 120.23 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC12CC3CC(C)(CC(C)(C3)C1)C2 CHEMBL5423643 IC50 126.0 nM
Fc1cc2c(Cc3c[nH]c4cc(Cl)c(F)cc34)c[nH]c2cc1Cl CHEMBL4104992 EC50 129.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])Oc1cccc2ccccc12 CHEMBL5417993 IC50 130.0 nM
c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2cccnn2)cc1 CHEMBL5177839 pIC50 141.25 nM
O=C(NCCO)c1ccc(-c2nc(Cc3c[nH]c4cnccc34)nnc2-c2ccccc2)cc1 CHEMBL5177947 pIC50 144.54 nM
CCCCCCSc1nc(O)cc(C(=O)O)n1 CHEMBL4442407 Ki 145.0 nM
O=P([O-])(OC1=Cc2ccccc2Oc2ccccc21)OC1=Cc2ccccc2Oc2ccccc21 CHEMBL5189167 IC50 146.0 nM
COc1ccc2c(c1)CCn1c-2cc(OCCOc2ccccc2)nc1=O CHEMBL4757870 IC50 156.0 nM
COc1cc2c(cc1OC)-c1cc(OCc3ccccc3)nc(=O)n1CC2 CHEMBL4795786 IC50 157.0 nM
O=P([O-])(OC1=Cc2ccccc2Sc2ccc(F)cc21)OC1=Cc2ccccc2Sc2ccc(F)cc21 CHEMBL5203023 IC50 165.0 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@@H]1OP(=O)([O-])OC1=Cc2ccccc2Sc2ccccc21 CHEMBL5434490 IC50 166.0 nM
Clc1cccc2[nH]cc(Cc3c[nH]c4cccc(Cl)c34)c12 CHEMBL4066454 EC50 175.0 nM
COC(=O)c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5196547 pIC50 181.97 nM
O=Nc1c(NCCCc2ccccc2)[nH]c(=O)[nH]c1=O CHEMBL4434708 Ki 189.0 nM
CS(=O)(=O)NCc1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5179309 pIC50 190.55 nM
CCCCCCCCCOP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5396626 IC50 194.0 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c3c2CCCC3)c1 CHEMBL5407571 pEC50 194.98 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])Oc1cc(C(C)C)ccc1C CHEMBL5421575 IC50 196.0 nM
CN1CCN(C(=O)c2ccc(-c3nnc(Cc4c[nH]c5ccccc45)nc3-c3ccccc3)cc2)CC1=O CHEMBL5193904 pIC50 204.17 nM
CN(C)Cc1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5184825 pIC50 208.93 nM
COC(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccc(C(=O)OC)cc2)cc1 CHEMBL5175765 pIC50 213.8 nM
COc1ccc(-c2nnc(Cc3n[nH]c4ccccc34)nc2-c2ccc(OC)cc2)cc1 CHEMBL5181719 pIC50 213.8 nM
CCCCCCCCP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5420273 IC50 219.0 nM
O=P([O-])(O/C1=C/c2ccccc2/C=C\c2ccccc21)O/C1=C/c2ccccc2/C=C\c2ccccc21 CHEMBL5179740 IC50 220.0 nM
O=c1cc(CCOc2ccc(Cl)c3ccccc23)cc[nH]1 CHEMBL5436803 EC50 222.0 nM
Fc1ccc2c(Cc3nnc(-c4ccccc4)c(-c4ccccc4)n3)c[nH]c2c1 CHEMBL5179128 pIC50 223.87 nM
CCCCCCNc1[nH]c(=O)[nH]c(=O)c1Br CHEMBL4456565 Ki 225.0 nM
CCCCCCCSc1nc(O)cc(O)n1 CHEMBL3827763 EC50 231.0 nM
O=P([O-])(OC1=Cc2ccccc2Sc2cc(F)ccc21)OC1=Cc2ccccc2Sc2cc(F)ccc21 CHEMBL5190004 IC50 234.0 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@@H]1OP(=O)([O-])OC1=Cc2c(Cl)cccc2Sc2ccccc21 CHEMBL5395766 IC50 238.0 nM
Cc1cc(OCCc2ccc[n+]([O-])c2)cc(C)c1Cl CHEMBL5428112 pEC50 245.47 nM
Clc1ccc2[nH]cc(Cc3c[nH]c4ccc(Cl)cc34)c2c1 CHEMBL4096406 EC50 250.0 nM
[O-][n+]1cccc(CCOc2cccc3ccccc23)c1 CHEMBL5431514 pEC50 251.19 nM
c1ccc2c(Cc3c[nH]c4ccccc34)c[nH]c2c1 CHEMBL446452 EC50 252.0 nM
COc1cc2c(cc1OC)-c1cc(OCc3ccccc3F)nc(=O)n1CC2 CHEMBL4799579 IC50 252.0 nM
COc1ccc(OCCc2ccc[n+]([O-])c2)c2ccccc12 CHEMBL5411553 EC50 256.0 nM
[O-][n+]1cccc(CCCc2cccc3ccccc23)c1 CHEMBL5433568 EC50 257.0 nM
c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ncccn2)cc1 CHEMBL5195413 pIC50 263.03 nM
CCCCCCCCSc1nc(O)cc(O)n1 CHEMBL3827862 EC50 264.0 nM
Fc1ccc2[nH]cc(Cc3c[nH]c4ccccc34)c2c1 CHEMBL4075099 EC50 264.0 nM
O=c1cc(NCCCCCCCO)[nH]c(=O)[nH]1 CHEMBL4455292 Ki 267.0 nM
O=P([O-])(O/C1=C/c2ccccc2CCc2ccccc21)O/C1=C/c2ccccc2CCc2ccccc21 CHEMBL5170786 IC50 270.0 nM
CCc1ccc(CSc2nc(O)cc(O)n2)cc1 CHEMBL3827038 EC50 271.0 nM
O=P([O-])(OC1=Cc2cccc(F)c2Sc2ccccc21)OC1=Cc2cccc(F)c2Sc2ccccc21 CHEMBL5184044 IC50 277.0 nM
O=C(O)c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5194077 pIC50 281.84 nM
CCCCCCCC(C)c1nc(O)cc(O)n1 CHEMBL3828004 EC50 299.0 nM
Fc1ccc2c(Cc3c[nH]c4cc(F)ccc34)c[nH]c2c1 CHEMBL4082668 EC50 302.0 nM
O=P([O-])(OC1=Cc2ccc(F)cc2Sc2ccccc21)OC1=Cc2ccc(F)cc2Sc2ccccc21 CHEMBL5198261 IC50 305.0 nM
CCCCCCCCCCCCC(O)C(=O)O CHEMBL2004471 Ki 318.0 nM
CC(C)Oc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC(C)C)cccc21 CHEMBL5195223 IC50 321.0 nM
CNS(=O)(=O)c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5207475 pIC50 323.59 nM
CNC(=O)c1cccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)c1 CHEMBL5173991 pIC50 323.59 nM
[O-][n+]1cccc(CCCc2ccc(Cl)cc2)c1 CHEMBL5417376 pEC50 323.59 nM
CCCCCCOP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5407593 IC50 325.0 nM
Fc1cccc2[nH]cc(Cc3c[nH]c4cccc(F)c34)c12 CHEMBL4101219 EC50 328.0 nM
O=P([O-])(OC1=Cc2ccccc2Sc2c(F)cccc21)OC1=Cc2ccccc2Sc2c(F)cccc21 CHEMBL5207051 IC50 328.0 nM
CNC(=O)c1ccc(-c2nc(Cc3c[nH]c4cnccc34)nnc2-c2ccccc2)cc1 CHEMBL5196255 pIC50 331.13 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])OC12CC3CC(CC(C3)C1)C2 CHEMBL5431524 IC50 340.0 nM
N#CC1=Cc2ccccc2Sc2ccccc21 CHEMBL5170482 IC50 345.0 nM
COc1cc2c(cc1OC)-c1cc(OCc3ncccc3F)nc(=O)n1CC2 CHEMBL4760776 IC50 350.0 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c(Br)c2)c1 CHEMBL5426349 pEC50 363.08 nM
COc1cccc2c1Sc1c(OC)cccc1C(OP(=O)([O-])OC1=Cc3cccc(OC)c3Sc3c(OC)cccc31)=C2 CHEMBL5188247 IC50 369.0 nM
[O-][n+]1cccc(CCCOc2ccc(Cl)c3ccccc23)c1 CHEMBL5434775 EC50 370.0 nM
O=P([O-])(Oc1c2ccccc2cc2ccccc12)Oc1c2ccccc2cc2ccccc12 CHEMBL5174911 IC50 380.0 nM
COc1cc2c(cc1OC)-c1cc(OCC3CCCO3)nc(=O)n1CC2 CHEMBL4758226 IC50 383.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@H]1C[C@@H]2CC[C@H]1C2 CHEMBL5425683 IC50 396.0 nM
COC(=O)c1cccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)c1 CHEMBL5197127 pIC50 398.11 nM
Cc1cc(OCCc2ccc[n+]([O-])c2)cc(C)c1C CHEMBL5439662 pEC50 398.11 nM
O=P([O-])(OC1=Cc2cccc(Cl)c2Sc2ccccc21)OC1=Cc2cccc(Cl)c2Sc2ccccc21 CHEMBL5196283 IC50 403.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])O[C@H]1CCCC[C@@H]1C(C)C CHEMBL5433203 IC50 405.0 nM
CNS(=O)(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5177895 pIC50 407.38 nM
CCCCCCCCCCCC(O)CC(=O)O CHEMBL4456892 EC50 432.0 nM
CNC(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccncc34)nc2-c2ccccc2)cc1 CHEMBL5205576 pIC50 446.68 nM
CCCCCC#CCOP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5402662 IC50 450.0 nM
CCCCCCCCCCC[C@@H](O)CC(=O)O CHEMBL1232858 EC50 452.0 nM
CCCCCCc1nc(O)cc(O)n1 CHEMBL3827946 EC50 454.0 nM
CCCCCCNC(=O)c1cc(=O)[nH]c(=O)[nH]1 CHEMBL4518826 Ki 469.0 nM
COc1ccc2[nH]cc(Cc3c[nH]c4ccccc34)c2c1 CHEMBL4095532 EC50 495.0 nM
O=c1cc(NCCc2c[nH]c3ccccc23)[nH]c(=O)[nH]1 CHEMBL4470574 Ki 497.0 nM
[O-][n+]1cccc(COc2ccc(Cl)c3ccccc23)c1 CHEMBL5415598 EC50 497.0 nM
CC(C)(C)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3718208 IC50 500.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(-c3ccc(Cl)s3)ccc1-2 CHEMBL3716645 IC50 500.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(-c3cccc4ccccc34)ccc1-2 CHEMBL3717070 IC50 500.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc4ccccc34)ccc1-2 CHEMBL3718784 IC50 500.0 nM
CC(C)C1CC(COc2cc3n(c(=O)n2)CCc2cc(C#CC4CC4)ccc2-3)O1 CHEMBL3714950 IC50 500.0 nM
CNCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O CHEMBL3716896 IC50 500.0 nM
N#Cc1ccccc1-c1ccc2c(c1)CCn1c-2cc(OCC2CCCO2)nc1=O CHEMBL3716913 IC50 500.0 nM
O=C(O)c1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 CHEMBL3716749 IC50 500.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(-c3cccnc3)ccc1-2 CHEMBL3715834 IC50 500.0 nM
CN(C)CCCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O CHEMBL3716911 IC50 500.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 CHEMBL3717849 IC50 500.0 nM
O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCC3CCCO3)ccc1-2 CHEMBL3718665 IC50 500.0 nM
CC(C)(Oc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O)C(=O)N1CCOCC1 CHEMBL3714778 IC50 500.0 nM
COc1ccc2c(c1)CCn1c-2cc(OCC2Cc3ccccc3O2)nc1=O CHEMBL3717778 IC50 500.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(OCCF)ccc1-2 CHEMBL3719125 IC50 501.0 nM
CC1(COCc2ccc3c(c2)CCn2c-3cc(OC[C@@H]3COCCO3)nc2=O)COC1 CHEMBL3717001 IC50 501.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#Cc3ncccn3)ccc1-2 CHEMBL3718076 IC50 501.0 nM
CCn1cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3718711 IC50 501.0 nM
Cc1cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)ccn1 CHEMBL3719139 IC50 501.0 nM
N#Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cn1 CHEMBL3716848 IC50 501.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(C#CCCO)ccc1-2 CHEMBL3717936 IC50 501.0 nM
NC(=O)c1cc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)ccc1F CHEMBL3716729 IC50 501.0 nM
N#Cc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1 CHEMBL3718792 IC50 501.0 nM
O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccncc3)ccc1-2 CHEMBL3716680 IC50 501.0 nM
CN(c1ccc2c(c1)CCn1c-2cc(OC[C@@H]2COCCO2)nc1=O)C1CCCCC1 CHEMBL3718852 IC50 501.0 nM
O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1cc(NCC3CCOCC3)ccc1-2 CHEMBL3716225 IC50 501.0 nM
O=c1nc(OC[C@H]2COCCO2)cc2n1CCc1cc(C#CC3(O)CCOCC3)ccc1-2 CHEMBL3714871 IC50 501.0 nM
CC(C)OCCOc1ccc2c(c1)CCn1c-2cc(OC[C@H]2COCCO2)nc1=O CHEMBL3716099 IC50 501.0 nM
CC/C=C\CCCCOP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5439033 IC50 517.0 nM
CCCCCCCCNP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5404018 IC50 547.0 nM
CC(=O)NCCNC(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5176916 pIC50 549.54 nM
O=C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 CHEMBL4087824 EC50 553.0 nM
CN1c2ccccc2C=C(OP(=O)([O-])OC2=Cc3ccccc3N(C)c3ccccc32)c2ccccc21 CHEMBL5170871 IC50 553.0 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@@H]1OP(=O)([O-])OC1=Cc2c(F)cccc2Sc2ccccc21 CHEMBL5412502 IC50 554.0 nM
[O-][n+]1cccc(NCCc2ccc(Cl)cc2)c1 CHEMBL5397948 pEC50 588.84 nM
COc1ccc2c(c1)CCn1c-2cc(OCc2ncccc2F)nc1=O CHEMBL4757413 IC50 595.0 nM
CCc1cc(OCCc2ccc[n+]([O-])c2)ccc1Cl CHEMBL5420353 pEC50 602.56 nM
O=P([O-])(O/C(=C\c1ccccc1)C1C=CC=CC1)O/C(=C\c1ccccc1)C1C=CC=CC1 CHEMBL5196041 IC50 604.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])Oc1ccc2ccccc2c1 CHEMBL5418028 IC50 609.0 nM
O=c1c2ccccc2cc(OP(=O)([O-])Oc2cc3ccccc3c(=O)c3ccccc23)c2ccccc12 CHEMBL5184962 IC50 613.0 nM
c1ccc(-c2nc(Cc3c[nH]c4cnccc34)nnc2-c2ccnnc2)cc1 CHEMBL5187711 pIC50 616.6 nM
CN(C)Cc1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5175411 pIC50 630.96 nM
CC(C)CCCSc1nc(O)cc(O)n1 CHEMBL3828230 EC50 641.0 nM
CCC#CCCSc1nc(O)cc(O)n1 CHEMBL3828212 EC50 653.0 nM
COc1cccc2c1Sc1ccccc1C=C2OP(=O)([O-])Oc1cc(C)ccc1C(C)C CHEMBL5400422 IC50 658.0 nM
CS(=O)(=O)c1ccc(-c2nnc(Cc3c[nH]c4ccccc34)nc2-c2ccccc2)cc1 CHEMBL5195677 pIC50 660.69 nM
O=C(CCc1ccc(Cl)cc1)c1ccc[n+]([O-])c1 CHEMBL5408077 pEC50 660.69 nM
CC1(C)[C@@H]2CC[C@@](C)(C2)[C@@H]1OP(=O)([O-])OC1=Cc2ccccc2Oc2ccccc21 CHEMBL5413350 IC50 711.0 nM
COc1cc2c(cc1OC)-c1cc(NCc3ccccc3)nc(=O)n1CC2 CHEMBL1871173 IC50 735.0 nM
[O-][n+]1cccc(CCOc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 CHEMBL5406066 EC50 776.0 nM
COc1cc2c(cc1OC)-c1cc(OCCc3ccccc3)nc(=O)n1CC2 CHEMBL4752941 IC50 808.0 nM
CCCCCCCCc1cc(O)nc(O)n1 CHEMBL3827933 EC50 811.0 nM
CCCCCCCOP(=O)([O-])OC1=Cc2ccccc2Sc2c(OC)cccc21 CHEMBL5404966 IC50 817.0 nM
CS(=O)(=O)c1ccc(-c2nc(Cc3c[nH]c4ccccc34)nnc2-c2ccccc2)cc1 CHEMBL5205328 pIC50 870.96 nM
COc1ccc2c(c1)CCn1c-2cc(OCC2COc3cccnc3O2)nc1=O CHEMBL4748375 IC50 873.0 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c(Cl)c2)c1 CHEMBL5419261 pEC50 891.25 nM
[O-][n+]1cccc(CCOc2ccc(Cl)c(C(F)(F)F)c2)c1 CHEMBL5417372 pEC50 891.25 nM
CC/C=C\CCSc1nc(O)cc(O)n1 CHEMBL3828033 EC50 938.0 nM
[O-][n+]1cccc(CCOc2ccc(I)cc2)c1 CHEMBL5410540 pEC50 977.24 nM
Cc1cccc2[nH]cc(Cc3c[nH]c4cccc(C)c34)c12 CHEMBL4077871 EC50 987.0 nM