Cn1nnc(-c2onc(O)c2C[C@H](N)C(=O)O)n1 CHEMBL370038 Ki 2.7 nM
N[C@@H](Cn1nc(Cl)c(=O)[nH]c1=O)C(=O)O CHEMBL331696 Ki 3.6 nM
N[C@@H](Cn1nc(Br)c(=O)[nH]c1=O)C(=O)O CHEMBL331644 Ki 7.9 nM
N[C@@H](Cn1nc(I)c(=O)[nH]c1=O)C(=O)O CHEMBL121553 Ki 19.9 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(I)cc1 CHEMBL63355 EC50 22.6 nM
CC(C)S(=O)(=O)N[C@H]1CCC[C@@H]1c1ccc(I)cc1 CHEMBL294506 EC50 32.8 nM
Cc1onc(O)c1CC(N)C(=O)O CHEMBL13378 Ki 40.0 nM
Cc1onc(O)c1C[C@H](N)C(=O)O CHEMBL276815 Ki 40.0 nM
CCn1nnc(-c2onc(O)c2CC(N)C(=O)O)n1 CHEMBL370941 Ki 44.4 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3C#N)cc2)c(C(=O)O)n1C CHEMBL384847 EC50 53.0 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(Br)cc1 CHEMBL63417 EC50 68.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3SC)cc2)c(C(=O)O)n1C CHEMBL215090 EC50 77.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3F)cc2)c(C(=O)O)n1C CHEMBL215575 EC50 80.0 nM
CC(C)S(=O)(=O)N[C@H]1CCC[C@@H]1c1ccc(Br)cc1 CHEMBL304375 EC50 82.1 nM
Cc1nn(C[C@H](N)C(=O)O)c(=O)[nH]c1=O CHEMBL120808 Ki 89.0 nM
NS(=O)(=O)c1cccc2c1c([N+](=O)[O-])cc1nc(O)c(O)nc12 CHEMBL222519 Kb 102.0 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1cc(F)cc(F)c1 CHEMBL67021 EC50 118.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(N)cc2)cc1 CHEMBL136801 EC50 130.0 nM
CCOc1ccccc1-c1ccc(-c2c(C#N)c(CC)n(C)c2C(=O)O)cc1 CHEMBL384271 EC50 146.0 nM
CC(C)S(=O)(=O)NC[C@H](C)c1ccc(-c2ccc(CCNS(C)(=O)=O)cc2)cc1 CHEMBL1277001 EC50 150.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3Cl)cc2)c(C(=O)O)n1C CHEMBL384402 EC50 157.0 nM
N[C@@H](Cc1nsnc1O)C(=O)O CHEMBL429594 Ki 182.0 nM
CCc1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL214833 EC50 183.0 nM
N[C@@H](Cn1ncc(=O)[nH]c1=O)C(=O)O CHEMBL122656 Ki 189.0 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc([N+](=O)[O-])cc1 CHEMBL63514 EC50 190.0 nM
N[C@@H](Cn1cc([N+](=O)[O-])c(=O)[nH]c1=O)C(=O)O CHEMBL121191 Ki 207.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3)cc2)c(C(=O)O)n1C CHEMBL385608 EC50 213.0 nM
CSc1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL213197 EC50 214.0 nM
CCc1c(C#N)c(-c2ccc(-c3cccc(F)c3)cc2)c(C(=O)O)n1C CHEMBL215574 EC50 223.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccc(F)cc3)cc2)c(C(=O)O)n1C CHEMBL214599 EC50 242.0 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(Cl)cc1 CHEMBL63816 EC50 247.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(C=O)cc2)cc1 CHEMBL343972 EC50 250.0 nM
Cc1ccc(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)cc1 CHEMBL343571 EC50 270.0 nM
CC(C)(C)c1ccc(-c2c(C(=O)O)sc(C(F)(F)F)c2C#N)cc1 CHEMBL214834 EC50 273.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(C#N)cc2)cc1 CHEMBL435582 EC50 290.0 nM
N[C@@H](Cn1cc(F)c(=O)[nH]c1=O)C(=O)O CHEMBL123132 Ki 305.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccc(C#N)cc3)cc2)c(C(=O)O)n1C CHEMBL384953 EC50 373.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3OC)cc2)c(C(=O)O)n1C CHEMBL215013 EC50 386.0 nM
CSc1c(C#N)c(-c2ccc(-c3ccccc3)cc2)c(C(=O)O)n1C CHEMBL385220 EC50 394.0 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(C#N)cc1 CHEMBL304468 EC50 403.0 nM
N=C(N)NCCC[C@H](N)C(=O)NCCCNCCCNCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1ccc(O)cc1O CHEMBL1098240 IC50 430.0 nM
Cc1ccc([C@H]2CCC[C@H]2NS(=O)(=O)C(C)C)cc1 CHEMBL67936 EC50 434.0 nM
CCSc1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL215987 EC50 440.0 nM
N[C@@H](Cn1cc(Cl)c(=O)[nH]c1=O)C(=O)O CHEMBL121388 Ki 451.0 nM
N[C@@H](Cn1cc(Br)c(=O)[nH]c1=O)C(=O)O CHEMBL333964 Ki 457.0 nM
CN(C)c1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL218347 EC50 474.0 nM
C[S+]([O-])c1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL378065 EC50 489.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(NC(=O)c3ccccc3)cc2)cc1 CHEMBL68282 EC50 520.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL105076 EC50 520.0 nM
Cc1c(C#N)c(-c2ccc(-c3ccccc3)cc2)c(C(=O)O)n1C CHEMBL215272 EC50 532.0 nM
N[C@@H](CC(C(=O)O)=C1CCCC1)C(=O)O CHEMBL51660 Ki 533.0 nM
CC(C)S(=O)(=O)N[C@H]1CCC[C@@H]1c1ccccc1 CHEMBL304865 EC50 551.0 nM
CSc1c(C#N)c(-c2ccc(C(C)(C)C)cc2)c(C(=O)O)n1C CHEMBL384010 EC50 554.0 nM
CCSc1c(C#N)c(-c2ccc(-c3ccccc3)cc2)c(C(=O)O)n1C CHEMBL214732 EC50 619.0 nM
CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1cccc(F)c1 CHEMBL307094 EC50 621.0 nM
CC(C)(C)c1ccc(-c2c(C(=O)O)sc(S(C)(=O)=O)c2C#N)cc1 CHEMBL217111 EC50 629.0 nM
CCc1c(C#N)c(-c2ccc(-c3cccc(C#N)c3)cc2)c(C(=O)O)n1C CHEMBL214804 EC50 631.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccsc2)cc1 CHEMBL334920 EC50 660.0 nM
Cn1c(Br)c(C#N)c(-c2ccc(-c3ccccc3)cc2)c1C(=O)O CHEMBL385704 EC50 679.0 nM
CCCn1nnc(-c2onc(O)c2CC(N)C(=O)O)n1 CHEMBL372643 Ki 732.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccc(OC)cc3)cc2)c(C(=O)O)n1C CHEMBL385384 EC50 738.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccccc3C)cc2)c(C(=O)O)n1C CHEMBL214903 EC50 790.0 nM
CSc1sc(C(=O)O)c(-c2ccc(-c3ccccc3)cc2)c1C#N CHEMBL377662 EC50 795.0 nM
N[C@@H](CCC(=O)O)C(=O)O CHEMBL575060 Ki 868.0 nM
CCc1c(C#N)c(-c2ccc(-c3ccc(Cl)cc3)cc2)c(C(=O)O)n1C CHEMBL385652 EC50 910.0 nM
N[C@@H](Cn1cc(I)c(=O)[nH]c1=O)C(=O)O CHEMBL121915 Ki 972.0 nM
CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccccc2)cc1 CHEMBL137506 EC50 1000.0 nM