Cc1ncc(CNNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)cn2)s1 CHEMBL4450420 IC50 7.9 nM
N#C[C@H]1C[C@H]1c1c(C(F)(F)F)sc2nc(Cn3nc(C(F)(F)F)cc3Cl)cc(=O)n12 CHEMBL5171984 EC50 11.0 nM
Cc1ncc(CNNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(F)c3)c(C)n2)s1 CHEMBL4555447 IC50 27.0 nM
C[C@]12N[C@H](Cc3ccccc31)c1ccccc12 CHEMBL284237 IC50 29.0 nM
N#C[C@H]1C[C@H]1c1c(Cl)ccc2nc(Cn3nc(C(F)(F)F)cc3Cl)cc(=O)n12 CHEMBL5180445 EC50 39.0 nM
O=C(NNC(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cc1)c1ccccc1 CHEMBL2333945 IC50 109.0 nM
CCN(Cc1cc(C)n(C[C@H]2C[C@@H]2C#N)c(=O)c1)c1ccc(F)cc1 CHEMBL5272286 EC50 110.0 nM
CCN(Cc1cc(C)n(C[C@@H]2C[C@H]2C#N)c(=O)c1)c1ccc(F)cc1 CHEMBL5266998 EC50 150.0 nM
Cc1cn([C@H](C)CC#N)c(=O)c2cc(Cn3nc(C(F)F)cc3Cl)nn12 CHEMBL5092058 EC50 510.0 nM
Cc1cc(Cn2nc(Br)cc2Cl)cc(=O)n1C[C@H]1C[C@@H]1C#N CHEMBL5273123 EC50 900.0 nM