N=C(NCc1cc(Cl)cc(Cl)c1)c1ccc(OC(F)(F)F)cc1 CHEMBL161180 Ki 0.6 nM
COc1ccccc1C/N=C(N)/C=C/c1ccccc1 CHEMBL158737 Ki 0.7 nM
Cc1cc(C)cc(C/N=C(\N)c2ccc(OC(F)(F)F)cc2)c1 CHEMBL159744 Ki 1.2 nM
O=C(OCc1ccccc1)N1CCC(CNc2ccncc2)CC1 CHEMBL219060 EC50 1.6 nM
O=[N+]([O-])c1ccc2c(c1)CCC(NCCCc1ccccc1)CC2 CHEMBL3735947 Ki 1.6 nM
Cc1cc(C)cc(CN2Cc3cc(OC(F)(F)F)ccc3C2=N)c1 CHEMBL429656 Ki 2.0 nM
Clc1ccc2c(c1)CCC(NCCCc1ccccc1)CC2 CHEMBL4637295 Ki 2.1 nM
N=C1c2ccc(OC(F)(F)F)cc2CN1Cc1cccc2ccoc12 CHEMBL393670 Ki 2.2 nM
c1ccc([C@H]2CC[C@@H](NC3CCc4ccccc4CC3)CC2)cc1 CHEMBL3357791 Ki 2.3 nM
c1ccc(CC2CCN(C3CCc4ccccc4CC3)CC2)cc1 CHEMBL3357790 Ki 2.9 nM
c1ccc(CC2CCN(C3Cc4ccccc4C3)CC2)cc1 CHEMBL4758763 Ki 3.2 nM
O=[N+]([O-])c1ccc2c(c1)CCC(NCCc1ccccc1)CC2 CHEMBL3735485 Ki 3.3 nM
Cc1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1 CHEMBL218713 Ki 3.4 nM
COc1ccccc1CN1Cc2cc(OC(F)(F)F)ccc2C1=N CHEMBL247323 Ki 3.6 nM
CCc1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1 CHEMBL218211 Ki 3.7 nM
O=[N+]([O-])c1ccc2c(c1)CCC(NCCCCc1ccccc1)CC2 CHEMBL3736502 Ki 3.8 nM
Cc1cc(C)cc(C/N=C(\N)c2ccc(C(F)(F)F)cc2)c1 CHEMBL162080 Ki 3.9 nM
COc1ccccc1C/N=C(\N)c1ccc(OC(F)(F)F)cc1 CHEMBL159560 IC50 4.1 nM
O=C1[C@H](N2CCC(c3ccc(O)cc3)CC2)CCN1Cc1ccc(F)cc1 CHEMBL4111330 IC50 4.2 nM
Nc1nccn1Cc1cn(-c2ccc(Cl)c(C(=O)C(F)F)c2)nn1 CHEMBL5416465 IC50 4.2 nM
c1ccc(C2CCN(C3Cc4ccccc4C3)CC2)cc1 CHEMBL4745685 Ki 4.5 nM
COc1ccc2c(c1)CCN(CCCCc1ccccc1)CC2O CHEMBL1289403 Ki 5.4 nM
c1ccc([C@H]2CC[C@H](NC3CCc4ccccc4CC3)CC2)cc1 CHEMBL3357792 Ki 5.7 nM
c1ccc(CC2CCN(CCCc3ccc4[nH]ncc4c3)CC2)cc1 CHEMBL5410173 Ki 5.7 nM
C[C@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL493054 Ki 5.8 nM
CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL305187 Ki 5.8 nM
c1ccc(CCCNC2CCc3ccsc3CC2)cc1 CHEMBL4634358 Ki 5.9 nM
CN(CCCc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4645707 Ki 6.0 nM
Cc1ccc(CN2CC[C@@H](N3CC[C@@H](c4ccc(O)cc4)[C@H](F)C3)C2=O)cc1 CHEMBL3892956 Ki 6.3 nM
C(=C/c1ccc2[nH]ncc2c1)\CN1CCC(Cc2ccccc2)CC1 CHEMBL5421604 Ki 6.6 nM
c1ccc(C2CCN(C3CCc4ccccc4CC3)CC2)cc1 CHEMBL3357788 Ki 6.9 nM
O=[N+]([O-])c1ccc2c(c1)CCC(NCc1ccccc1)CC2 CHEMBL3735173 Ki 7.6 nM
C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL49623 Kd 7.6 nM
CC(C)c1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1 CHEMBL386184 Ki 7.8 nM
C[C@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL113830 Ki 7.8 nM
Oc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCCCC1 CHEMBL2013195 pIC50 7.943 nM
Oc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCCCCC1 CHEMBL2013196 pIC50 7.943 nM
Oc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCCC1 CHEMBL2013197 pIC50 7.943 nM
N=C1c2ccc(OC(F)(F)F)cc2CN1Cc1cccc(Cl)c1 CHEMBL247718 Ki 8.0 nM
c1ccc(CC2CCN(C3CCc4ccccc4C3)CC2)cc1 CHEMBL4740593 Ki 8.0 nM
c1ccc(C2CCN(C3CCc4ccccc4C3)CC2)cc1 CHEMBL4746028 Ki 8.4 nM
N=C(/C=C/c1ccccc1)NCc1ccccc1 CHEMBL158874 Ki 9.0 nM
N#Cc1cccc2c1C=Cc1ncc(-c3ccccc3)cc1C2O CHEMBL570613 IC50 9.0 nM
C[C@@H](CN1CCC(Cc2ccccc2)CC1)[C@@H](O)c1ccc(O)cc1 CHEMBL305195 IC50 9.0 nM
CN(CCCCc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4648500 Ki 9.0 nM
COc1cccc(C/N=C(\N)c2ccc(OC(F)(F)F)cc2)c1 CHEMBL349727 IC50 9.7 nM
COc1ccc2c(c1)CCC(NCCCc1ccccc1)CC2 CHEMBL3357784 Ki 10.0 nM
C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL319706 Ki 10.0 nM
c1ccc(CCCCNC2CCc3ccsc3CC2)cc1 CHEMBL4646690 Ki 11.0 nM
C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCC(O)(c2ccccc2)CC1 CHEMBL17350 IC50 11.0 nM
C(#Cc1ccc2[nH]ncc2c1)CN1CCC(Cc2ccccc2)CC1 CHEMBL114644 Ki 11.0 nM
N=C(NCc1ccccc1OC(F)(F)F)c1ccc(Cl)c(Cl)c1 CHEMBL161876 Ki 12.0 nM
c1ccc(N2CCN(C3CCc4ccccc4CC3)CC2)cc1 CHEMBL3357789 Ki 12.0 nM
COc1ccc2c(c1)CC[C@H](NCCCc1ccccc1)C[C@@H]2O CHEMBL4287203 IC50 12.0 nM
Cc1nccn1Cc1cc(-c2ccc(F)c(C(F)F)c2)cnn1 CHEMBL3545350 IC50 12.0 nM
Oc1ccc(C#CCN2CCC(Cc3ccc(F)cc3)CC2)cc1 CHEMBL5441115 Ki 12.0 nM
Oc1ccc2[nH]c(-c3cccc(F)c3F)nc2c1CN1CCCC1 CHEMBL2013204 pIC50 12.59 nM
OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 CHEMBL28564 Ki 13.0 nM
Brc1cc2c(s1)CCC(NCCCc1ccccc1)CC2 CHEMBL4632765 Ki 13.0 nM
Fc1ccc(CC2CCN(CC#Cc3ccc4[nH]ncc4c3)CC2)cc1 CHEMBL5435194 Ki 13.0 nM
Fc1ccc(CC2CCN(CCCc3ccc4[nH]ncc4c3)CC2)cc1 CHEMBL5432456 Ki 13.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2cnccn2)CC1 CHEMBL220660 Ki 14.0 nM
N=C(NCc1cccc(Cl)c1)c1ccc(Cl)c(Cl)c1 CHEMBL159818 Ki 16.0 nM
COc1ccc2c(c1)CCC(NCCCc1ccccc1)CC2O CHEMBL3357783 Ki 16.0 nM
c1ccc(CCCNC2CCc3ccccc3CC2)cc1 CHEMBL296601 Ki 16.0 nM
COc1ccc2c(c1)CC[C@@H](NCCCc1ccccc1)C[C@H]2O CHEMBL4294561 Ki 16.0 nM
c1ccc(CCCCNC2CCc3ccccc3CC2)cc1 CHEMBL3357787 Ki 17.0 nM
FC(CNC1CCc2ccccc2CC1)Cc1ccccc1 CHEMBL4283845 Ki 17.0 nM
O=C(OCc1ccc(F)cc1)N1CCC(CNc2ncccn2)CC1 CHEMBL218275 Ki 18.0 nM
O=C(OCc1ccccc1F)N1CCC(CNc2ncccn2)CC1 CHEMBL221605 Ki 18.0 nM
O=C(CCN1CCC(Cc2ccccc2)CC1)c1ccc2[nH]ncc2c1 CHEMBL5398972 Ki 18.0 nM
N=C(NCc1cccc(Cl)c1)c1ccc(C(F)(F)F)cc1 CHEMBL159558 Ki 20.0 nM
c1ccc(CCNC2CCc3ccccc3CC2)cc1 CHEMBL3357786 Ki 20.0 nM
O=C(CCN1CCC(Cc2ccccc2F)CC1)c1ccc2[nH]ncc2c1 CHEMBL5406518 Ki 20.0 nM
Fc1ccc(CC2CCN(C/C=C/c3ccc4[nH]ncc4c3)CC2)cc1 CHEMBL5423529 Ki 20.0 nM
Oc1ccc2c(c1)CCC(NCCCCc1ccccc1)CC2 CHEMBL4284348 Ki 21.0 nM
O=C(OC1Cc2ccccc2C1)N1CCC(CNc2ncccn2)CC1 CHEMBL221133 Ki 23.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2ncccn2)CC1 CHEMBL435316 Ki 23.0 nM
Brc1cc2c(s1)CCC(NCCCCc1ccccc1)CC2 CHEMBL4645300 Ki 23.0 nM
Fc1ccccc1CC1CCN(CC#Cc2ccc3[nH]ncc3c2)CC1 CHEMBL5409908 Ki 25.0 nM
c1ccc(CNC2CCc3ccsc3CC2)cc1 CHEMBL4574247 Ki 26.0 nM
N#Cc1cccc2c1C=Cc1ncc(N3CCCCC3)cc1C2O CHEMBL569802 IC50 27.0 nM
FC(CCc1ccccc1)CNC1CCc2ccccc2CC1 CHEMBL4288292 Ki 27.0 nM
Oc1ccc2c(c1)CCC(NCCCc1ccccc1)CC2 CHEMBL4286654 Ki 28.0 nM
Cn1ncc2cc(C#CCN3CCC(Cc4ccc(F)cc4)CC3)ccc21 CHEMBL5396018 Ki 29.0 nM
O=c1[nH]c2ccc([S+]([O-])CCN3CCC(Cc4ccc(F)cc4)CC3)cc2o1 CHEMBL219631 Ki 30.0 nM
FCC[C@H]1Cc2ccccc2C2(CCC(N3CCN(C4CCCCC4)CC3)CC2)O1 CHEMBL4170858 Ki 31.0 nM
Oc1ccc2[nH]c(-c3ccccc3)nc2c1CNC1CCCC1 CHEMBL2013198 pIC50 31.62 nM
c1ccc(CCCCN2CCCc3ccccc3CC2)cc1 CHEMBL4778291 Ki 32.0 nM
OC(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc2[nH]ncc2c1 CHEMBL5410339 Ki 32.0 nM
c1ccc(CCNC2CCc3ccsc3CC2)cc1 CHEMBL4646841 Ki 33.0 nM
CCN(CCCCc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4641623 Ki 33.0 nM
O[C@H]1Cc2ccccc2C2(CCC(N3CCN(C4CCCCC4)CC3)CC2)O1 CHEMBL4169479 Ki 34.0 nM
Nc1n[nH]c(SCCN2CCC(Cc3ccccc3)CC2)n1 CHEMBL151901 IC50 35.0 nM
Fc1ccc(CC2CCN(CC#Cc3ccc4cn[nH]c4c3)CC2)cc1 CHEMBL5429038 Ki 35.0 nM
c1ccc(CCCN2CCCc3ccccc3CC2)cc1 CHEMBL4754021 Ki 36.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2ccccn2)CC1 CHEMBL218017 Ki 37.0 nM
Cn1ncc2cc(C#CCN3CCC(Cc4ccccc4)CC3)ccc21 CHEMBL5425955 Ki 38.0 nM
OC(CCN1CCC(Cc2ccccc2)CC1)c1ccc2[nH]ncc2c1 CHEMBL5432037 Ki 38.0 nM
OC(CCN1CCC(Cc2ccccc2F)CC1)c1ccc2[nH]ncc2c1 CHEMBL5416753 Ki 38.0 nM
CCCNCc1c(O)ccc2[nH]c(-c3ccccc3)nc12 CHEMBL2013199 pIC50 39.81 nM
Oc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCOCC1 CHEMBL2013200 pIC50 39.81 nM
Cc1ccc(-c2nc3c(CNC4CC4)c(O)ccc3[nH]2)cc1 CHEMBL2013207 pIC50 39.81 nM
Fc1ccc(CC2CCN(C/C=C\c3ccc4[nH]ncc4c3)CC2)cc1 CHEMBL5408501 Ki 42.0 nM
N=C(NCc1ccccc1)c1ccc(OC(F)(F)F)cc1 CHEMBL161421 IC50 46.0 nM
N=C(NCc1ccccc1C(F)(F)F)c1ccc(OC(F)(F)F)cc1 CHEMBL159279 IC50 47.0 nM
N=C(NCc1ccccc1Cl)c1ccc(C(F)(F)F)cc1 CHEMBL421976 IC50 48.0 nM
COc1ccc2c(c1)CC[C@H](NCCCc1ccccc1)C[C@H]2O CHEMBL4590193 Ki 48.0 nM
Oc1ccc2c3c([nH]c2c1)CN(CCCCc1ccccc1)CC3 CHEMBL44301 IC50 50.0 nM
CCN(CCCc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4648377 Ki 51.0 nM
C(#Cc1ccc2cn[nH]c2c1)CN1CCC(Cc2ccccc2)CC1 CHEMBL5435626 Ki 53.0 nM
CCOC(=O)C[C@H]1Cc2ccccc2C2(CCC(N3CCN(C4CCCCC4)CC3)CC2)O1 CHEMBL4159233 Ki 54.0 nM
O=C(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc2[nH]ncc2c1 CHEMBL5431988 Ki 56.0 nM
c1ccc(CNC2CCc3ccccc3CC2)cc1 CHEMBL3357785 Ki 57.0 nM
Cc1ccc(CN2CCCN(C(=O)c3cc4ccccc4o3)CC2)c(C)c1 CHEMBL4643805 Ki 59.0 nM
Oc1ccc(-c2cc3c(s2)CCC(NCCCc2ccccc2)CC3)cc1 CHEMBL4649725 Ki 60.0 nM
Cc1cccc2sc(NC(=O)CCN3CCN(CC4CCCCC4)CC3)nc12 CHEMBL5204934 Ki 60.0 nM
CCN(Cc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4647186 Ki 61.0 nM
O[C@H](CCN1CCC(Cc2ccccc2)CC1)c1ccc2[nH]ncc2c1 CHEMBL5435354 IC50 62.0 nM
N=C(NCc1cccc(Cl)c1)c1ccc(Cl)cc1 CHEMBL161871 Ki 63.0 nM
FCC[C@@H]1Cc2ccccc2C2(CCC(N3CCN(C4CCCCC4)CC3)CC2)O1 CHEMBL4170683 Ki 65.0 nM
FC(F)(F)Oc1ccc(C2=NCC(c3cccc(Cl)c3)N2)cc1Cl CHEMBL429475 Ki 66.0 nM
c1ccc(CCCCNC2Cc3ccccc3C2)cc1 CHEMBL4800530 Ki 66.0 nM
c1ccc(CC2CCN(CCSc3ncc[nH]3)CC2)cc1 CHEMBL147355 IC50 70.0 nM
CN(Cc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4647243 Ki 72.0 nM
O[C@@H](CCN1CCC(Cc2ccccc2)CC1)c1ccc2[nH]ncc2c1 CHEMBL5417143 IC50 72.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2ccncn2)CC1 CHEMBL218068 Ki 75.0 nM
COc1ccccc1C1CN=C(c2ccc(OC(F)(F)F)c(Cl)c2)N1 CHEMBL397784 Ki 75.0 nM
Cc1ccc(CN2CCCN(C(=O)c3cccc4ccccc34)CC2)c(C)c1 CHEMBL4644807 Ki 79.0 nM
Oc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCC(c2ccccc2)CC1 CHEMBL2013201 pIC50 79.43 nM
Fc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCCC1 CHEMBL2010883 pIC50 79.43 nM
Fc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCCCC1 CHEMBL2010884 pIC50 79.43 nM
Oc1ccc2c(c1)CCN(CCCCc1ccccc1)CC2O CHEMBL1289626 Ki 84.0 nM
Oc1ccc(CCCN2CCc3c([nH]c4ccccc34)C2)cc1 CHEMBL44412 IC50 87.0 nM
c1ccc(COc2ccc(CCNc3ccncc3)cc2)cc1 CHEMBL48029 Ki 93.0 nM
Oc1ccc(C#CCCN2CCC(Cc3ccccc3)CC2)cc1 CHEMBL83781 IC50 100.0 nM
Oc1ccc(SCCN2CCC(Cc3ccccc3)CC2)cc1 CHEMBL151174 IC50 100.0 nM
OCc1ccc2c(c1)CCC(NCCCc1ccccc1)CC2 CHEMBL4294991 Ki 101.0 nM
Cc1ccc(CN2CCCN(C(=O)c3ccc4ccccc4n3)CC2)c(C)c1 CHEMBL4640137 Ki 108.0 nM
CCCCCCN1CCN(CCC(=O)Nc2nc3c(C)cccc3s2)CC1 CHEMBL5192784 Ki 115.0 nM
Cc1ccc(CN2CCCN(C(=O)c3ccncc3)CC2)c(C)c1 CHEMBL4643145 Ki 116.0 nM
c1ccc(CCCNC2Cc3ccccc3C2)cc1 CHEMBL55317 Ki 117.0 nM
C(=C\c1ccc2[nH]ncc2c1)\CN1CCC(Cc2ccccc2)CC1 CHEMBL5440346 Ki 120.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2nccs2)CC1 CHEMBL218547 Ki 122.0 nM
Nc1ccc2c(c1)CCC(NCc1ccccc1)CC2 CHEMBL4570472 Ki 128.0 nM
c1ccc(CC2CCN(CCSc3nc[nH]n3)CC2)cc1 CHEMBL347753 IC50 130.0 nM
CN(CCc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4632628 Ki 130.0 nM
Cn1cc2cc(C#CCN3CCC(Cc4ccccc4)CC3)ccc2n1 CHEMBL5403196 Ki 136.0 nM
Oc1ccc2[nH]c3c(c2c1)CCN(CCCCc1ccccc1)C3 CHEMBL43928 IC50 140.0 nM
CN(CCCc1ccccc1)C1CCc2cc(CO)sc2CC1 CHEMBL4637655 Ki 141.0 nM
Cc1n[nH]c(SCCN2CCC(Cc3ccccc3)CC2)n1 CHEMBL146764 IC50 150.0 nM
O=C(OCc1cccc(F)c1)N1CCC(CNc2ncccn2)CC1 CHEMBL374865 Ki 150.0 nM
c1ccc(CCCNC2CCc3ccccc3C2)cc1 CHEMBL25858 Ki 163.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2cccnc2)CC1 CHEMBL218067 Ki 180.0 nM
Cn1cc2cc(C#CCN3CCC(Cc4ccc(F)cc4)CC3)ccc2n1 CHEMBL5394862 Ki 182.0 nM
OCc1cc2c(s1)CCC(NCCCc1ccccc1)CC2 CHEMBL4637229 Ki 183.0 nM
Cc1cccc2sc(NC(=O)CCN3CCN(c4ccncc4)CC3)nc12 CHEMBL5206534 Ki 184.0 nM
OCc1ccc2c(c1)CCC(NCCCCc1ccccc1)CC2 CHEMBL4287755 Ki 186.0 nM
CC(=O)c1ccc(N2CCN(CCC(=O)Nc3nc4c(C)cccc4s3)CC2)cc1 CHEMBL5176580 Ki 187.0 nM
O=C(OCc1ccccc1)N1CCC(CNc2nncs2)CC1 CHEMBL219113 Ki 190.0 nM
Oc1ccc2c(c1)CCN(CCCCc1ccc(OCCF)cc1)CC2O CHEMBL4439555 Ki 193.0 nM
CCN(CCc1ccccc1)C1CCc2ccsc2CC1 CHEMBL4644644 Ki 196.0 nM
Fc1ccc2[nH]c(-c3ccccc3)nc2c1CN1CCCCCC1 CHEMBL2010885 pIC50 199.53 nM
Cc1cccc2sc(NC(=O)CCN3CCN(CCN(C(C)C)C(C)C)CC3)nc12 CHEMBL5205006 Ki 202.0 nM
OC1CC(NCc2ccccc2)CCc2sccc21 CHEMBL4513837 Ki 204.0 nM
Cc1cccc(COC(=O)N2CCC(CNc3ncccn3)CC2)c1 CHEMBL218104 Ki 206.0 nM
Nc1nnc(SCCN2CCC(Cc3ccccc3)CC2)s1 CHEMBL358256 IC50 210.0 nM
Cc1cccc2sc(NC(=O)CCN3CCN(C4CCCCC4)CC3)nc12 CHEMBL5203777 Ki 213.0 nM
O=C(OCc1ccccc1)N1CCC(Cc2nc3ccccc3[nH]2)CC1 CHEMBL218546 Ki 220.0 nM
FC(F)(F)Oc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)N2)cc1Cl CHEMBL247113 Ki 223.0 nM
Cc1ccccc1COC(=O)N1CCC(CNc2ncccn2)CC1 CHEMBL425462 Ki 227.0 nM
O=C(OCCc1ccccc1)N1CCC(CNc2ncccn2)CC1 CHEMBL219114 Ki 227.0 nM
CCCCN1CCN(CCC(=O)Nc2nc3c(C)cccc3s2)CC1 CHEMBL5192987 Ki 229.0 nM
FC(F)Oc1cc(-c2cnn(Cc3cc[nH]n3)c2)ccc1Cl CHEMBL3897632 IC50 230.0 nM
c1ccc(CCNC2CCc3ccccc3C2)cc1 CHEMBL4745317 Ki 237.0 nM
c1ccc(CC2CCN(CCSc3nc4ccc[nH]c-4n3)CC2)cc1 CHEMBL150641 IC50 240.0 nM
CN(C)Cc1c(O)ccc2[nH]c(-c3ccccc3)nc12 CHEMBL2013202 pIC50 251.19 nM
COc1cc(F)ccc1-c1cncc(CNC(=O)c2cnccn2)c1 CHEMBL1779012 IC50 262.0 nM
c1ccc(CCCN2CCC(CNc3ncccn3)CC2)cc1 CHEMBL218075 Ki 266.0 nM
c1ccc(CCCCNC2CCc3ccccc3C2)cc1 CHEMBL4759924 Ki 266.0 nM
Cc1ccc(CN2CCCN(C(=O)c3ccccc3)CC2)c(C)c1 CHEMBL4636728 Ki 294.0 nM
FC(F)(F)Oc1ccc(C2=NCC(c3cccc(Cl)c3)N2)cc1 CHEMBL247717 Ki 296.0 nM
O=C(CCc1ccccc1)N1CCC(CNc2ncccn2)CC1 CHEMBL217955 Ki 310.0 nM
FC(F)Oc1cc(-c2cnn(Cc3cn[nH]c3)c2)ccc1Cl CHEMBL3927856 IC50 350.0 nM
FC(F)(F)Oc1ccc(C2=NCC(c3ccccc3C(F)(F)F)N2)cc1Cl CHEMBL247114 Ki 353.0 nM
N=C(NCc1ccccc1)c1ccc(C(F)(F)F)cc1 CHEMBL159530 IC50 360.0 nM
Fc1ccc(-c2cnn(Cc3cc[nH]n3)c2)cc1OC(F)F CHEMBL3954438 IC50 370.0 nM
c1ccc(CC2CCN(CCSc3nc4ccccc4[nH]3)CC2)cc1 CHEMBL148767 IC50 380.0 nM
CN1CCN(Cc2c(O)ccc3[nH]c(-c4ccccc4)nc23)CC1 CHEMBL2013203 pIC50 398.11 nM
c1ccc(-c2nc3c(CN4CCCCC4)cccc3[nH]2)cc1 CHEMBL2010880 pIC50 398.11 nM
N=C(NCc1cccc(Cl)c1)c1cccc(Cl)c1 CHEMBL162081 IC50 420.0 nM
N=C(NCc1cccc(Cl)c1)c1ccc(F)cc1 CHEMBL159879 IC50 450.0 nM
c1ccc(CCNC2Cc3ccccc3C2)cc1 CHEMBL4759856 Ki 455.0 nM
Cc1cccc2sc(NC(=O)CCN3CCN(CC4CCCO4)CC3)nc12 CHEMBL5207817 Ki 457.0 nM
COc1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1 CHEMBL217904 Ki 460.0 nM
COc1ccc2c(c1)CCN(CCCC#Cc1ccccc1)CC2O CHEMBL4472450 Ki 460.0 nM
Cc1cccc2sc(NC(=O)CCN3CCN(C(C)(C)C)CC3)nc12 CHEMBL5171428 Ki 476.0 nM
FC(F)(F)Oc1ccc(C2=NCC(c3ccccc3OC(F)(F)F)N2)cc1Cl CHEMBL247115 Ki 505.0 nM
COc1cc(F)ccc1-c1cncc(CNCC2CC2)n1 CHEMBL1778865 IC50 508.0 nM
CC(OC(=O)N1CCC(CNc2ncccn2)CC1)c1ccccc1 CHEMBL425642 Ki 540.0 nM
Nc1nnc(SCCCN2CCC(Cc3ccccc3)CC2)s1 CHEMBL150403 IC50 560.0 nM
c1ccc(CC2CCN(CCCSc3ncc[nH]3)CC2)cc1 CHEMBL151339 IC50 610.0 nM
c1ccc(CC2CCN(CCCSc3nc[nH]n3)CC2)cc1 CHEMBL151428 IC50 630.0 nM
Nc1n[nH]c(SCCCN2CCC(Cc3ccccc3)CC2)n1 CHEMBL151389 IC50 630.0 nM
Oc1ccc2[nH]c(-c3cccc(F)c3F)nc2c1CNCc1cccs1 CHEMBL2013205 pIC50 630.96 nM
N=C(NCc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 CHEMBL348360 IC50 660.0 nM
COc1cc(F)ccc1-c1cncc(CNC(=O)c2ccccn2)c1 CHEMBL1779013 IC50 673.0 nM
Cn1c(=O)n(C)c2cc3c(cc21)CCCC(NCCCc1ccccc1)C3 CHEMBL3797704 Ki 697.0 nM
N=C(NCc1ccccc1)c1ccc(Cl)cc1 CHEMBL161977 IC50 720.0 nM
CC(C)(C)c1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1 CHEMBL217940 Ki 720.0 nM
CN(CCc1ccccc1)C1CCc2cc(CO)sc2CC1 CHEMBL4642875 Ki 726.0 nM
OCc1cc2c(s1)CCC(NCCCCc1ccccc1)CC2 CHEMBL4644834 Ki 764.0 nM
O=C(CN1CCC(Cc2ccccc2)CC1)c1c[nH]c2ccccc12 CHEMBL444384 IC50 769.0 nM
COc1cc(F)ccc1-c1cncc(CNC2CCCC2)c1 CHEMBL1779003 IC50 770.0 nM
Oc1ccc2[nH]c(-c3cccc(F)c3F)nc2c1CNCc1ccco1 CHEMBL2013206 pIC50 794.33 nM
CC(C)NCc1c(F)ccc2[nH]c(-c3ccccc3)nc12 CHEMBL2010886 pIC50 794.33 nM
FC(F)c1cc(-c2cnn(Cc3cc[nH]n3)c2)ccc1Cl CHEMBL3975087 IC50 890.0 nM
O=[N+]([O-])c1ccc2[nH]c(SCCCN3CCC(Cc4ccccc4)CC3)nc2c1 CHEMBL147200 IC50 910.0 nM
c1ccc(CC2CCN(CCSc3ccccc3)CC2)cc1 CHEMBL151489 IC50 930.0 nM
c1ccc(CC2CCN(CCCSc3nc4ccccc4[nH]3)CC2)cc1 CHEMBL147295 IC50 1000.0 nM
Cc1n[nH]c(SCCCN2CCC(Cc3ccccc3)CC2)n1 CHEMBL358601 IC50 1000.0 nM
CCC1CCCCN1Cc1c(F)ccc2[nH]c(-c3ccccc3)nc12 CHEMBL2010887 pIC50 1000.0 nM