CCCn1c(CNc2cccc(C(=O)NCc3c(F)cccc3F)c2)nnc1-c1ccncn1 CHEMBL1738878 IC50 1.2 nM
O=C(NCc1c(F)cccc1F)c1cccc(NCc2nnc3n2CCOc2cnccc2-3)c1 CHEMBL4073882 IC50 1.7 nM
O=C(NCc1ccccc1C(F)(F)F)c1cccc(NCc2nnc3n2CCOc2cnccc2-3)c1 CHEMBL4072828 IC50 1.8 nM
CCCn1c(CNc2cccc(C(=O)NCc3ccccc3C(F)(F)F)c2)nnc1-c1ccncn1 CHEMBL4086046 IC50 1.9 nM
CC(=O)Nc1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1Cl CHEMBL3716385 IC50 2.0 nM
CC(=O)Nc1cc(NC(C)(C)C(=O)Nc2nc3ccc4[nH]ncc4c3s2)ccc1Cl CHEMBL3718650 IC50 2.8 nM
COc1ccccc1CNC(=O)c1cccc(NCc2nnc(-c3ccncc3)[nH]2)c1 CHEMBL4095659 IC50 3.0 nM
CCC(=O)Nc1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1Cl CHEMBL3716440 IC50 3.2 nM
CC(C)(Nc1ccc(Cl)c(C(N)=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3719041 IC50 3.2 nM
CC(=O)Nc1cc(NC2(C(=O)Nc3nc4ccc5[nH]ncc5c4s3)CC2)ccc1F CHEMBL3718067 IC50 3.7 nM
O=C(Nc1nc2ccc3[nH]ncc3c2s1)C1(Nc2ccc(Cl)cc2)CC1 CHEMBL3718984 IC50 3.9 nM
CCC(=O)Nc1cc(NC(C)(C)C(=O)Nc2nc3ccc4[nH]ncc4c3s2)ccc1Cl CHEMBL3718849 IC50 3.9 nM
O=C(NCc1ccccc1Cl)c1cccc(NCc2nnc(-c3ccncc3)[nH]2)c1 CHEMBL4077447 IC50 3.9 nM
O=C(CNc1ccc(Cl)c(O)c1)Nc1nc2ccc3[nH]ncc3c2s1 CHEMBL3716298 IC50 4.0 nM
CCNC(=O)c1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1Cl CHEMBL3719096 IC50 4.5 nM
CCC(=O)Nc1cc(NC2(C(=O)Nc3nc4ccc5[nH]ncc5c4s3)CC2)ccc1F CHEMBL3715310 IC50 4.6 nM
O=C(NCc1ccccc1C(F)(F)F)c1cccc(NCc2nnc(-c3ccncc3)n2CCO)c1 CHEMBL4071398 IC50 5.5 nM
COc1cccc(Cn2cnc3ccc(-c4cn[nH]c4)cc3c2=O)c1 CHEMBL4742990 IC50 6.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4082775 IC50 6.1 nM
Cc1cc2[nH]ncc2c2sc(NC(=O)C3(Nc4ccc(Cl)cc4)CC3)nc12 CHEMBL3714916 IC50 6.2 nM
CNC(=O)c1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1Cl CHEMBL3717041 IC50 6.3 nM
CCNC(=O)c1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1F CHEMBL3716102 IC50 6.4 nM
Cn1c(CNc2cccc(C(=O)NCc3c(F)cccc3F)c2)nnc1-c1ccncn1 CHEMBL4103972 IC50 6.8 nM
CNC(=O)c1cc(NC2(C(=O)Nc3nc4ccc5[nH]ncc5c4s3)CC2)ccc1Cl CHEMBL3717989 IC50 7.5 nM
CCn1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 CHEMBL4083276 IC50 7.5 nM
O=C(Nc1nc2ccc3[nH]ncc3c2s1)C(CO)Nc1ccc(Cl)cc1 CHEMBL3716137 IC50 7.7 nM
CC(C)(Nc1ccc(Cl)c(C(=O)NCCCC(=O)O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3716175 IC50 7.7 nM
CC(C)(Nc1ccc(Cl)c(C(=O)NCC(=O)O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3717935 IC50 7.7 nM
CC(C)(Nc1cccc(O)c1)C(=O)Nc1nc2ccc3[nH]ncc3c2s1 CHEMBL3718495 IC50 7.8 nM
Cn1c(CNc2cccc(C(=O)NCc3ccccc3C(F)(F)F)c2)nnc1-c1ccncn1 CHEMBL4094447 IC50 7.8 nM
CC(C)(Nc1ccc(Cl)c(C(=O)NCCC(=O)O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3716523 IC50 7.9 nM
CC(Nc1ccc(Cl)cc1)C(=O)Nc1nc2ccc3[nH]ncc3c2s1 CHEMBL3719183 IC50 8.0 nM
CC(=O)Nc1cc(NCC(=O)Nc2nc3ccc4[nH]ncc4c3s2)ccc1Cl CHEMBL3716346 IC50 8.3 nM
CC(=O)Nc1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1F CHEMBL3716850 IC50 8.3 nM
CC(C)(Nc1ccc(Cl)c(O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3719241 IC50 8.7 nM
CCOC(=O)c1cc(NC2(C(=O)Nc3nc4ccc5[nH]ncc5c4s3)CC2)ccc1Cl CHEMBL3715386 IC50 8.7 nM
CC(C)(Nc1ccc(Cl)cc1)C(=O)Nc1nc2ccc3[nH]ncc3c2s1 CHEMBL3716615 IC50 8.8 nM
CC(C)(Nc1ccc(Cl)c(C(=O)NC2CC2)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3716279 IC50 8.8 nM
O=C(Nc1ccc(F)cc1)c1cccc(Cn2cnc3ccc(-c4cn[nH]c4)cc3c2=O)c1 CHEMBL4785990 IC50 9.0 nM
CCC(=O)Nc1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1F CHEMBL3715431 IC50 9.3 nM
CC(C)(Nc1cccc(S(N)(=O)=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3717691 IC50 9.3 nM
CC(=O)Nc1cc(NC(C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)c2ccccc2)ccc1Cl CHEMBL3714810 IC50 9.8 nM
CC(C)(Nc1ccc(Cl)c(C(=O)NCC(N)=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3716786 IC50 9.9 nM
Cc1c(-c2ccncc2)n[nH]c1CNc1cccc(C(=O)NCc2ccccc2)c1 CHEMBL4065690 IC50 9.9 nM
Cc1ccc(Oc2cccc(NCC(=O)N/N=C/c3ccncc3)c2)cc1 CHEMBL3731835 Ki 10.0 nM
O=C(CNc1cccc(Oc2ccc(F)cc2F)c1)N/N=C/c1ccncc1 CHEMBL3732726 Ki 10.0 nM
COc1ccc(Oc2cccc(NCC(=O)N/N=C/c3ccncc3)c2)cc1 CHEMBL3728531 Ki 10.0 nM
COc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3728772 Ki 10.0 nM
NC(=O)c1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3729453 Ki 10.0 nM
O=C(CNc1cccc(C(=O)NCCN2CCOCC2)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3732468 Ki 10.0 nM
COc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3732018 Ki 10.0 nM
O=C(NCC1CCOCC1)c1n[nH]c2ccc(-c3cncc(CO)c3)cc12 CHEMBL4640019 IC50 11.0 nM
CC(C)(Nc1ccc(Cl)c(-n2cc[nH]c2=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 CHEMBL3716599 IC50 12.0 nM
O=C(Cc1ccccc1)Nc1cc(NCc2nc(-c3ccncc3)n[nH]2)ccc1Cl CHEMBL4093075 IC50 12.0 nM
COc1cccc(CNC(=O)c2cccc(NCc3nnc(-c4ccncc4)[nH]3)c2)c1 CHEMBL4060973 IC50 12.0 nM
Cn1c(CNc2cccc(C(=O)NCc3ccccc3Cl)c2)nnc1-c1ccncc1 CHEMBL4061438 IC50 12.0 nM
CNCCC(c1cccc(OC)c1)n1cnc2ccc(-c3cn[nH]c3)cc2c1=O CHEMBL4753687 IC50 12.0 nM
COc1cccc([C@@H](C)n2cnc3ccc(-c4cn[nH]c4)cc3c2=O)c1 CHEMBL4782910 IC50 13.0 nM
COc1cccc(NCC(=O)N/N=C2\CCCc3cnccc32)c1 CHEMBL4082559 IC50 14.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2cc(-c3ccncc3)n[nH]2)c1 CHEMBL4087117 IC50 14.0 nM
COCCn1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 CHEMBL4064232 IC50 16.0 nM
COc1ccc(CNC(=O)c2cccc(NCc3nnc(-c4ccncc4)[nH]3)c2)cc1 CHEMBL4082853 IC50 17.0 nM
Cn1c(CNc2cccc(C(=O)NCc3ccccc3C(F)(F)F)c2)nnc1-c1ccncc1 CHEMBL1738877 IC50 18.0 nM
COc1cc(Cn2cnc3ccc(-c4cn[nH]c4)cc3c2=O)ccc1F CHEMBL4751285 IC50 18.0 nM
O=C(NCc1[nH]nc2ccccc12)c1cc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)ccc1F CHEMBL5414047 IC50 18.0 nM
O=C(NCc1ccccc1)Nc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4082805 IC50 19.0 nM
COc1cccc(Cn2ncc3ccc(-c4cn[nH]c4)cc3c2=O)c1 CHEMBL4744858 IC50 19.0 nM
Cn1cc(-c2cc(C(N)=O)nc3[nH]ncc23)c2cc(OCC(N)=O)ccc21 CHEMBL3715563 IC50 20.0 nM
O=C(CNc1cccc(C(=O)NCc2ccccc2)c1)N/N=C1\CCCc2cnccc21 CHEMBL4082713 IC50 20.0 nM
COc1cccc(OC)c1CNC(=O)c1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL3809020 IC50 20.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)c[nH]2)c1 CHEMBL4067877 IC50 21.0 nM
O=C(NCCCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4075063 IC50 23.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2cc(-c3ccncc3)on2)c1 CHEMBL4089087 IC50 24.0 nM
O=C(NCc1ccn[nH]1)c1cc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)ccc1F CHEMBL4090144 IC50 30.0 nM
CCCn1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 CHEMBL4070100 IC50 32.0 nM
O=C(NCCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4101739 IC50 38.0 nM
Cn1c(CNc2cccc(C(=O)NCc3cccc(C(F)(F)F)c3)c2)nnc1-c1ccncc1 CHEMBL4091573 IC50 39.0 nM
Clc1ccc(NCc2nc(-c3ccncc3)n[nH]2)cc1 CHEMBL4062560 IC50 41.0 nM
O=C(N[C@@H]1CNCCC[C@H]1OC(=O)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1)c1ccc(O)cc1 CHEMBL60254 IC50 42.0 nM
O=C(CNc1cccc(Oc2ccccc2)c1)N/N=C1\CCCc2cnccc21 CHEMBL4085247 IC50 42.0 nM
Cc1cnccc1-c1n[nH]c(CNc2cccc(C(=O)NCc3ccccc3)c2)n1 CHEMBL4062649 IC50 42.0 nM
NS(=O)(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4072686 IC50 44.0 nM
COc1ccccc1CNC(=O)c1cccc(NCc2nnc(-c3ccncc3)n2C)c1 CHEMBL4075992 IC50 44.0 nM
Cn1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 CHEMBL4086619 IC50 45.0 nM
Cn1c(CNc2cccc(C(=O)NCc3ccc(C(F)(F)F)cc3)c2)nnc1-c1ccncc1 CHEMBL4063774 IC50 45.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2cc(-c3ccncc3)no2)c1 CHEMBL4105466 IC50 46.0 nM
O=C(CNc1cccc(OCc2ccccc2)c1)N/N=C1\CCCc2cnccc21 CHEMBL4072224 IC50 53.0 nM
O=C(Nc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4076320 IC50 54.0 nM
O=C(c1ccccc1)c1c2c(cc3sc4ccccc4[n+]13)-c1cccc3cccc-2c13 CHEMBL1502014 EC50 60.0 nM
COc1ccccc1CNC(=O)c1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL3809965 IC50 60.0 nM
CNc1cc(-c2nnc(CNc3cccc(C(=O)NCc4c(F)cccc4F)c3)n2C)ccn1 CHEMBL4066027 IC50 62.0 nM
CNC(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4095595 IC50 65.0 nM
CC(=O)Nc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4085317 IC50 65.0 nM
Cn1c(CNc2cccc(C(=O)NCc3c(F)cccc3F)c2)nnc1-c1ccnc(NCc2ccccc2)c1 CHEMBL4095742 IC50 67.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nnc(-c3ccncc3)o2)c1 CHEMBL4096791 IC50 67.0 nM
NC(=O)c1cc[n+](CC2=C(C(=O)[O-])N3C(=O)[C@@H](NC(=O)[C@@H](c4ccccc4)S(=O)(=O)[O-])[C@H]3SC2)cc1 CHEMBL1590946 EC50 70.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3c(C)cccc3C)c2)NC(=O)N1 CHEMBL3809913 IC50 70.0 nM
O=c1c2cc(-c3cn[nH]c3)ccc2ncn1Cc1cccc(Oc2ccc(F)cc2)c1 CHEMBL4752236 IC50 78.0 nM
O=c1c2cc(-c3cn[nH]c3)ccc2ncn1Cc1ccccc1 CHEMBL4740635 IC50 95.0 nM
O=C(CNc1cccc(OCc2ccccc2)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3727997 Ki 100.0 nM
O=C(CNc1cccc(C(=O)Nc2ccccc2)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3728662 Ki 100.0 nM
O=C(CNc1cccc(C(=O)Nc2ccccc2)c1)N/N=C/c1ccncc1 CHEMBL3728346 Ki 100.0 nM
C/C(=N\NC(=O)CNc1cccc(C(=O)Nc2ccccc2)c1)c1ccncc1 CHEMBL3732155 Ki 100.0 nM
C/C(=N\NC(=O)CNc1cccc(Oc2ccccc2)c1)c1ccncc1 CHEMBL3729597 Ki 100.0 nM
COc1cccc(NCC(=O)N/N=C(\C)c2ccncc2)c1 CHEMBL3729044 Ki 100.0 nM
C/C(=N\NC(=O)CNc1cccc(OCc2ccccc2)c1)c1ccncc1 CHEMBL3731262 Ki 100.0 nM
O=C(CNc1cccc(Oc2cccnc2)c1)N/N=C/c1ccncc1 CHEMBL3728959 Ki 100.0 nM
O=C(CNc1cccc(Oc2ccc(F)c(F)c2)c1)N/N=C/c1ccncc1 CHEMBL3730343 Ki 100.0 nM
O=C(CNc1cccc(C(=O)Nc2cccnc2)c1)N/N=C/c1ccncc1 CHEMBL3727632 Ki 100.0 nM
O=C(CNc1cccc(C(=O)NCCN2CCOCC2)c1)N/N=C/c1ccncc1 CHEMBL3730425 Ki 100.0 nM
O=C(CNc1cccc(Oc2ccc(OC(F)(F)F)cc2)c1)N/N=C/c1ccncc1 CHEMBL3728261 Ki 100.0 nM
NS(=O)(=O)c1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3731114 Ki 100.0 nM
O=C(CNc1cccc(Oc2ccccc2)c1)N/N=C/c1ccncc1 CHEMBL3727728 Ki 100.0 nM
CNC(=O)c1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3729682 Ki 100.0 nM
O=C(CNc1cccc(I)c1)N/N=C/c1ccncc1 CHEMBL3729519 Ki 100.0 nM
CSc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3733136 Ki 100.0 nM
O=C(CNc1cccc(OCc2ccccc2)c1)N/N=C/c1ccncc1 CHEMBL3730555 Ki 100.0 nM
O=C(CNc1cccc(Br)c1)N/N=C/c1ccncc1 CHEMBL3732073 Ki 100.0 nM
O=C(CNc1ccccc1)N/N=C/c1ccncc1 CHEMBL3727506 Ki 100.0 nM
O=C(CNc1cccc(F)c1)N/N=C/c1ccncc1 CHEMBL3728684 Ki 100.0 nM
O=C(CNc1cccc(Cl)c1)N/N=C/c1ccncc1 CHEMBL3728445 Ki 100.0 nM
NS(=O)(=O)c1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3730586 Ki 100.0 nM
CCOc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3729412 Ki 100.0 nM
O=C(CNc1cccc(Oc2ccccc2)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3731472 Ki 100.0 nM
CNC(=O)c1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3729247 Ki 100.0 nM
CSc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3729970 Ki 100.0 nM
O=C(CNc1cccc(F)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3730250 Ki 100.0 nM
O=C(CNc1ccccc1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3730062 Ki 100.0 nM
c1ccc(NCc2nc(-c3ccncc3)n[nH]2)cc1 CHEMBL4091451 IC50 100.0 nM
O=S(=O)(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4091566 IC50 100.0 nM
C=C(C)C(=O)Nc1cccc(C2=NOC3(C2)C[C@@H](C(N)=O)N(C(=O)CCCCC)C3)c1 CHEMBL1517799 EC50 110.0 nM
Cn1c(CNc2cccc(C(=O)NCc3c(F)cccc3F)c2)nnc1-c1ccnc(NCCCc2ccccc2)c1 CHEMBL4088026 IC50 110.0 nM
C[C@@H](NC(=O)Nc1cc2[nH]ncc2c(CO)n1)c1ccccc1 CHEMBL4538174 Kd 110.0 nM
CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2CC)Sc2ccc3sccc3c21 CHEMBL1318350 EC50 120.0 nM
CCOc1cccc(NCC(=O)N/N=C2\CCCc3cnccc32)c1 CHEMBL4063621 IC50 120.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3c(Cl)cccc3Cl)c2)NC(=O)N1 CHEMBL3810271 IC50 130.0 nM
CC(=O)Nc1cc(NCc2nc(-c3ccncc3)n[nH]2)ccc1Cl CHEMBL4072308 IC50 130.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3CO)n[nH]2)c1 CHEMBL4098177 IC50 130.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2cc(-c3ccncc3)c[nH]2)c1 CHEMBL4104512 IC50 130.0 nM
Clc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4093686 IC50 140.0 nM
CC(C)n1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 CHEMBL4091067 IC50 140.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3ccccn3)c2)NC(=O)N1 CHEMBL3808660 IC50 150.0 nM
COc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4062967 IC50 160.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)cs2)c1 CHEMBL4100175 IC50 160.0 nM
COC(=O)C1(NC(=O)c2cc(C3NC(=O)NC(C)=C3C(=O)Nc3ccc4[nH]ncc4c3)ccc2F)CCCCC1 CHEMBL4228896 IC50 160.0 nM
CCc1nc(CNC(=O)c2cc(C3NC(=O)NC(C)=C3C(=O)Nc3ccc4[nH]ncc4c3)ccc2F)no1 CHEMBL4228779 IC50 160.0 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 CHEMBL4568087 IC50 160.0 nM
NC[C@@](O)(c1ccc(Cl)cc1)c1ccc(-c2cn[nH]c2)cc1 CHEMBL3544960 Kd apparent 170.0 nM
CC(=O)Nc1cc(-c2nnc(CNc3cccc(C(=O)NCc4ccccc4C(F)(F)F)c3)n2C)ccn1 CHEMBL4069432 IC50 170.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3cccc(F)c3)c2)NC(=O)N1 CHEMBL3809100 IC50 200.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)no2)c1 CHEMBL4082173 IC50 200.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(CC(=O)N3Cc4ccc(C)cc4C3)c2)NC(=O)N1 CHEMBL4225917 IC50 200.0 nM
O=c1c2cc(-c3cn[nH]c3)ccc2ncn1Cc1cccc(OC(F)F)c1 CHEMBL4782250 IC50 206.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3c(F)cccc3F)c2)NC(=O)N1 CHEMBL3808621 IC50 220.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCCc3c(C)cccc3C)c2)NC(=O)N1 CHEMBL3808918 IC50 230.0 nM
C[C@@]12C[C@@]3(O)O[C@H](O1)[C@@]1(COC(=O)c4ccccc4)[C@@H]3C[C@]12O[C@@H]1O[C@H](COS(=O)(=O)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1O CHEMBL5406336 IC50 236.4 nM
Clc1ccccc1NCc1nc(-c2ccncc2)n[nH]1 CHEMBL4060836 IC50 250.0 nM
Cn1c(CNc2cccc(C(=O)NCc3c(F)cccc3F)c2)nnc1-c1ccnc(NCCc2ccccc2)c1 CHEMBL4059737 IC50 250.0 nM
COCc1noc(CNC(=O)c2cc(C3NC(=O)NC(C)=C3C(=O)Nc3ccc4[nH]ncc4c3)ccc2F)n1 CHEMBL4225427 IC50 250.0 nM
CCOc1noc(CNC(=O)c2cc(C3NC(=O)NC(C)=C3C(=O)Nc3ccc4[nH]ncc4c3)ccc2F)n1 CHEMBL5412633 IC50 250.0 nM
Cn1cc(-c2cc(C(N)=O)cc3[nH]ncc23)c2ccccc21 CHEMBL3717114 IC50 270.0 nM
O=c1c2cc(-c3cn[nH]c3)c(F)cc2ncn1Cc1ccccc1 CHEMBL4755199 IC50 278.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCCc3ccccn3)c2)NC(=O)N1 CHEMBL3810107 IC50 280.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3nccc4ccccc34)c2)NC(=O)N1 CHEMBL3809796 IC50 280.0 nM
c1ccc(CCOc2cccc(NCc3nc(-c4ccncc4)n[nH]3)c2)cc1 CHEMBL4065514 IC50 280.0 nM
c1ccc(CSc2cccc(NCc3nc(-c4ccncc4)n[nH]3)c2)cc1 CHEMBL4064596 IC50 290.0 nM
c1ccc(Oc2cccc(NCc3nc(-c4ccncc4)n[nH]3)c2)cc1 CHEMBL4074131 IC50 300.0 nM
O=C(Cc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1)NCc1ccccc1 CHEMBL4100779 IC50 320.0 nM
CCOc1ccccc1NC(=O)CCS(=O)(=O)c1ccc(Br)cc1 CHEMBL1438650 EC50 337.2 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CN)C(=O)O CHEMBL2435840 IC50 340.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3cnc4c(c3)CCC4)c2)NC(=O)N1 CHEMBL4227081 IC50 340.0 nM
c1ccc(COc2cccc(NCc3nc(-c4ccncc4)n[nH]3)c2)cc1 CHEMBL4093174 IC50 360.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2nnc(-c3ccncc3)n2Cc2ccccc2)c1 CHEMBL4091972 IC50 370.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)cc2)NC(=O)N1 CHEMBL384073 IC50 390.0 nM
COc1ccccc1C(C)NC(=O)c1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL4227400 IC50 400.0 nM
COc1cccc(CNC(=O)c2cc(C3NC(=O)NC(C)=C3C(=O)Nc3ccc4[nH]ncc4c3)ccc2F)c1 CHEMBL3810312 IC50 420.0 nM
CCN(CC)c1ccc(NC(=O)CCS(=O)(=O)c2ccc(Br)cc2)c(C)c1 CHEMBL1371301 EC50 426.2 nM
CC#CCN(CCCC)C(=O)Cc1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL4225489 IC50 430.0 nM
COc1ccc(NCc2nc(-c3ccncc3)n[nH]2)cc1 CHEMBL4082714 IC50 440.0 nM
COc1cccc(OC)c1CNC(=O)Cc1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL3809124 IC50 450.0 nM
Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(N3CCCC3)cc2o1 CHEMBL3093151 IC50 460.0 nM
COc1ccc(CNC(=O)c2cc(C3NC(=O)NC(C)=C3C(=O)Nc3ccc4[nH]ncc4c3)ccc2F)cc1 CHEMBL3810073 IC50 460.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2c[nH]c(-c3ccncc3)n2)c1 CHEMBL4081217 IC50 460.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(CC(=O)N(CCO)Cc3ccco3)c2)NC(=O)N1 CHEMBL4229039 IC50 460.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2csc(-c3ccncc3)n2)c1 CHEMBL4072362 IC50 470.0 nM
O=c1c2cc(-c3cn[nH]c3)cc(F)c2ncn1Cc1ccccc1 CHEMBL4793755 IC50 472.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NC3CN4CCC3CC4)c2)NC(=O)N1 CHEMBL4225645 IC50 500.0 nM
O=C(NCc1ccccc1)c1cccc(NCc2[nH]nc(-c3ccncc3)c2-c2ccccc2)c1 CHEMBL4099309 IC50 510.0 nM
COCCN1CCC(CNC(=O)c2n[nH]c3ccc(-c4cccc(F)c4F)cc23)CC1 CHEMBL3735506 IC50 530.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3cn4ccccc4n3)c2)NC(=O)N1 CHEMBL4227138 IC50 540.0 nM
NC(=O)OCc1cnccc1-c1n[nH]c(CNc2cccc(C(=O)NCc3ccccc3)c2)n1 CHEMBL4090462 IC50 560.0 nM
O=C(NCC(F)(F)F)c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)cs1 CHEMBL4569508 IC50 610.0 nM
CC(CS(=O)(=O)c1ccc2c(c1)NC(=O)CS2)C(=O)NCc1ccccc1Cl CHEMBL1611255 EC50 638.3 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCCc3c(C)noc3C)c2)NC(=O)N1 CHEMBL4227666 IC50 640.0 nM
COc1ccc(N(C(=O)Nc2ccc3nc(-c4cc(-c5cnn(C6CCNCC6)c5)cnc4N)oc3c2)c2ccccc2)cc1 CHEMBL3093243 IC50 660.0 nM
CC(C)(CS(=O)(=O)[O-])NC(=O)CC[N+](C)(C)CCO CHEMBL1533230 EC50 670.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(CC(=O)NCC3CCN(C4CC4)CC3)c2)NC(=O)N1 CHEMBL4227350 IC50 680.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3ccccc3)c2)NC(=O)N1 CHEMBL3808840 IC50 690.0 nM
COc1ccc(CNC(=O)CCS(=O)(=O)c2ccc(Br)cc2)cc1 CHEMBL1730248 EC50 700.0 nM
Cn1cc(-c2cc(C(N)=O)nc3[nH]ncc23)c2cc(OCC3CCCNC3)ccc21 CHEMBL3715293 IC50 700.0 nM
CN(Cc1ccccc1)C(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 CHEMBL4063713 IC50 700.0 nM
CCCN(C(=O)c1cccc(-n2cccc2)c1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O CHEMBL1562896 EC50 720.0 nM
C=C(C)C(=O)Nc1cccc(C2=NOC3(C2)C[C@@H](C(N)=O)N(C(=O)c2ccc(Cl)cc2)C3)c1 CHEMBL1542453 EC50 730.0 nM
CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(CC(=O)N(CCCO)CCCO)c2)NC(=O)N1 CHEMBL4228314 IC50 750.0 nM
COc1ccc(Cl)cc1NC(=O)CCS(=O)(=O)c1ccc(Br)cc1 CHEMBL1538897 EC50 778.9 nM
CCC(C)CN(CCO)C(=O)Cc1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL4228055 IC50 830.0 nM
Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2cc(N3CCCCC3)ccc2o1 CHEMBL3093258 IC50 850.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 879.0 nM
C#CCN(Cc1ccco1)C(=O)Cc1cc(C2NC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]ncc3c2)ccc1F CHEMBL4228945 IC50 920.0 nM
Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(NC(=O)c3ccc(F)cc3)cc2o1 CHEMBL3093247 IC50 960.0 nM
Clc1ccc(CNc2nc(-c3ccncc3)n[nH]2)cc1 CHEMBL4071201 IC50 980.0 nM
O=C(CNc1cccc(Cl)c1)N/N=C/c1ccoc1 CHEMBL3731185 Ki 1000.0 nM
O=C(CNc1ccccc1Cc1ccccc1)N/N=C/c1ccncc1 CHEMBL3727587 Ki 1000.0 nM
N#Cc1ccc(NCC(=O)N/N=C/c2ccncc2)cc1 CHEMBL3731340 Ki 1000.0 nM
CCc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3732076 Ki 1000.0 nM
CC(C)Oc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3728377 Ki 1000.0 nM
O=C(CNc1ccc(Cl)cc1)N/N=C/c1ccncc1 CHEMBL3731521 Ki 1000.0 nM
O=C(CNc1ccc(F)cc1)N/N=C/c1ccncc1 CHEMBL3728275 Ki 1000.0 nM
O=C(CNc1cccc(C(F)(F)F)c1)N/N=C/c1ccncc1 CHEMBL3732237 Ki 1000.0 nM
Cc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3732001 Ki 1000.0 nM
N#Cc1cccc(NCC(=O)N/N=C/c2ccncc2)c1 CHEMBL3730458 Ki 1000.0 nM
O=C(CNc1ccc(Br)cc1)N/N=C/c1ccncc1 CHEMBL3727996 Ki 1000.0 nM
Cc1ccc(Oc2cccc(NCC(=O)N/N=C/c3c(Cl)cncc3Cl)c2)cc1 CHEMBL3729359 Ki 1000.0 nM
O=C(CNc1cccc(OCCN2CCOCC2)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3731839 Ki 1000.0 nM
CC(=O)Nc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3727962 Ki 1000.0 nM
CCc1ccccc1NCC(=O)N/N=C/c1c(Cl)cncc1Cl CHEMBL3730611 Ki 1000.0 nM
Cc1ccccc1NCC(=O)N/N=C/c1c(Cl)cncc1Cl CHEMBL3730286 Ki 1000.0 nM
CS(=O)(=O)Nc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3727573 Ki 1000.0 nM
CS(=O)(=O)c1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3731537 Ki 1000.0 nM
CC(C)Oc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3731647 Ki 1000.0 nM
O=C(CNc1ccc(Cl)cc1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3732611 Ki 1000.0 nM
Cc1ccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)cc1 CHEMBL3728666 Ki 1000.0 nM
O=C(CNc1ccc(F)cc1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3727963 Ki 1000.0 nM
O=C(CNc1cccc(I)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3728259 Ki 1000.0 nM
Cc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3729052 Ki 1000.0 nM
O=C(CNc1cccc([N+](=O)[O-])c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3728097 Ki 1000.0 nM
O=C(CNc1cccc(Br)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3730299 Ki 1000.0 nM
N#Cc1cccc(NCC(=O)N/N=C/c2c(Cl)cncc2Cl)c1 CHEMBL3733170 Ki 1000.0 nM
O=C(CNc1cccc(Cl)c1)N/N=C/c1c(Cl)cncc1Cl CHEMBL3732736 Ki 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM