N[C@@]1(C(=O)O)CC(=O)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL2381640 EC50 0.11 nM
N[C@@]1(C(=O)O)C[S+]([O-])[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL218710 Ki 0.17 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccccc2O)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4068189 EC50 0.17 nM
N[C@@]1(C(=O)O)C[C@@H](F)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL2381652 EC50 0.24 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2cccc(Cl)c2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4071962 Ki 0.47 nM
COc1cccc(C(=O)N[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)c1 CHEMBL4081453 EC50 0.47 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2cccc(O)c2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4091735 EC50 0.71 nM
N[C@](CC1c2ccccc2Oc2ccccc21)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL432038 Ki 1.3 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2cccc(F)c2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4091203 EC50 2.0 nM
N[C@@]1(C(=O)O)CC(=O)[C@@H]2[C@H]1[C@@]2(F)C(=O)O CHEMBL121053 EC50 2.07 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccc(O)cc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4070866 EC50 2.12 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccc(Cl)cc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4095567 Ki 2.29 nM
COc1ccc(C(=O)N[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)cc1 CHEMBL4061162 EC50 2.44 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSc1ccc(F)c(F)c1 CHEMBL4751065 Ki 2.5 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](Sc2nc[nH]n2)[C@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3969063 Ki 2.7 nM
N[C@H](C(=O)O)[C@H]1[C@@H](O)[C@@H]1C(=O)O CHEMBL140197 Ki 3.0 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccc(F)cc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4063336 Ki 4.34 nM
N[C@]1(C(=O)O)[C@H]2[C@@H](C[C@H]1OCc1ccc(Cl)c(Cl)c1)[C@]2(F)C(=O)O CHEMBL186453 Ki 4.5 nM
Cc1cc(SC[C@@H]2[C@@H](Sc3nc[nH]n3)[C@H]3[C@H](C(=O)O)[C@H]3[C@]2(N)C(=O)O)ccc1F CHEMBL4759992 Ki 4.5 nM
N[C@@]1(C(=O)O)CO[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL275079 EC50 4.58 nM
N[C@@]1(C(=O)O)CS[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL8839 Ki 4.7 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4095995 EC50 4.96 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccccc2Cl)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4098939 EC50 4.96 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)c2ccccc2F)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4090293 EC50 5.1 nM
Cc1cc(SC[C@@H]2[C@@H](O)[C@H]3[C@H](C(=O)O)[C@H]3[C@]2(N)C(=O)O)ccc1F CHEMBL4780402 Ki 5.9 nM
N[C@@]1(C(=O)O)C[C@H](O)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL2381643 IC50 6.3 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSc1ccc(F)cc1 CHEMBL4776989 Ki 6.8 nM
COc1ccccc1C(=O)N[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL4099470 EC50 7.15 nM
N[C@@]1(C(=O)O)CSC2C1[C@H]2C(=O)O CHEMBL88999 Ki 7.6 nM
CC(=O)N[C@H]1[C@H]2[C@H](C(=O)O)[C@H]2[C@](N)(C(=O)O)[C@@H]1CSc1ccc(F)c(C)c1 CHEMBL4746125 Ki 7.7 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSc1ccc(Cl)c(Cl)c1 CHEMBL4748699 Ki 9.4 nM
N[C@@]1(C(=O)O)C[C@@H](O)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL2381642 IC50 11.2 nM
[N-]=[N+]=N[C@@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL2381644 EC50 12.3 nM
CC(=O)N[C@H]1[C@H]2[C@H](C(=O)O)[C@H]2[C@](N)(C(=O)O)[C@@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3913414 IC50 14.3 nM
C=C1C[C@@](N)(C(=O)O)[C@H]2[C@@H]1[C@@H]2C(=O)O CHEMBL2381641 EC50 15.5 nM
N[C@@](CC1c2ccccc2Oc2ccccc21)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL144151 IC50 16.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSCc1ccc(Cl)c(Cl)c1 CHEMBL4760856 Ki 16.3 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSc1ccccc1 CHEMBL4759209 Ki 19.2 nM
COC(=O)N[C@H]1[C@H]2[C@H](C(=O)O)[C@H]2[C@](N)(C(=O)O)[C@@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3939492 IC50 20.5 nM
N[C@@]1(C(=O)O)CC[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL8759 Activity 21.0 nM
[N-]=[N+]=N[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL2381645 EC50 23.5 nM
N[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL2381647 EC50 24.9 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSc1cccc(F)c1 CHEMBL4784701 Ki 25.1 nM
Cc1ccc(SC[C@@H]2[C@@H](O)[C@H]3[C@H](C(=O)O)[C@H]3[C@]2(N)C(=O)O)cc1C CHEMBL4757159 Ki 26.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1CSc1ccccc1 CHEMBL4781638 Ki 26.0 nM
N[C@@]1(C(=O)O)C[C@H](Sc2nnc(C(F)F)[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616857 EC50 27.3 nM
Cn1ncnc1S[C@H]1[C@H]2[C@H](C(=O)O)[C@H]2[C@](N)(C(=O)O)[C@@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3948272 IC50 29.6 nM
N[C@@]1(C(=O)O)C[C@H](Sc2nnc(C(F)(F)F)[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616856 EC50 30.5 nM
C[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL365368 EC50 34.0 nM
O=C1c2cc(COc3ccc(F)cc3)nn2CCN1c1ccc(F)cc1 CHEMBL3745812 EC50 34.0 nM
Cc1cc(SC[C@@H]2[C@@H](N)[C@H]3[C@H](C(=O)O)[C@H]3[C@]2(N)C(=O)O)ccc1F CHEMBL4756556 Ki 36.1 nM
C[C@H]1[C@H](C(=O)O)[C@H]1[C@H](N)C(=O)O CHEMBL334160 Activity 38.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](Sc2ncc[nH]2)[C@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3977508 IC50 38.5 nM
N[C@]1(C(=O)O)[C@H]2[C@@H](C[C@@H]1F)[C@@H]2C(=O)O CHEMBL334014 Activity 45.4 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3947221 IC50 46.1 nM
N[C@@]1(C(=O)O)CS(=O)(=O)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL375611 EC50 48.0 nM
[N-]=[N+]=N[C@H]1[C@H]2[C@H](C(=O)O)[C@H]2[C@](N)(C(=O)O)[C@@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3933829 IC50 54.1 nM
N[C@@]1(C(=O)O)C[C@@H](Sc2nnc(C(F)(F)F)[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616849 Ki 56.7 nM
N[C@@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL2381646 EC50 57.1 nM
N[C@@H](CCC(=O)O)C(=O)O CHEMBL575060 pKi 57.54 nM
Nc1nnc(S[C@@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)[nH]1 CHEMBL3616851 Ki 58.3 nM
Cc1nnc(S[C@@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)[nH]1 CHEMBL3616848 Ki 62.4 nM
N[C@@]1(C(=O)O)C[C@@H](Sc2nnc(C(F)F)[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616850 Ki 63.2 nM
N[C@@]1(C(=O)O)C[C@H](Sc2c[nH]nn2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616860 Ki 65.1 nM
Nc1nnc(S[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)[nH]1 CHEMBL3616858 Ki 69.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](F)[C@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3961306 IC50 71.0 nM
O=C1c2cc(COc3ccccc3)nn2CCN1c1ccc(F)cc1 CHEMBL3747735 EC50 74.0 nM
N[C@@]1(C(=O)O)[C@H](Cc2ccc(F)c(Cl)c2)C[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3956934 IC50 76.1 nM
CC(C)c1nnc(S[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)[nH]1 CHEMBL3616859 EC50 77.9 nM
Cc1nnc(S[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)[nH]1 CHEMBL3616855 Ki 79.0 nM
Cc1cccc(CC[C@](N)(C(=O)O)[C@H]2C[C@@H]2C(=O)O)c1 CHEMBL124501 IC50 80.0 nM
NC(CCc1cccc(C(=O)O)c1)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2112634 IC50 80.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1cccc(Cl)c1Cl CHEMBL3918170 IC50 83.2 nM
Cc1cc(CO[C@@H]2[C@H](O)[C@H]3[C@H](C(=O)O)[C@H]3[C@]2(N)C(=O)O)ccc1F CHEMBL3927108 IC50 85.0 nM
N[C@@]1(C(=O)O)CC[C@@H]2[C@H]1[C@@]2(F)C(=O)O CHEMBL333519 Activity 89.0 nM
N[C@]1(C(=O)O)C2C(C[C@H]1O)[C@@H]2C(=O)O CHEMBL330097 Ki 100.0 nM
N[C@@]1(C(=O)O)C[C@H](Sc2nnc[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616854 Ki 126.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1ccc(Cl)c(F)c1 CHEMBL3890112 IC50 127.0 nM
N[C@@]1(C(=O)O)C[C@@H](Sc2nnc[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616847 EC50 129.0 nM
N[C@@]1(C(=O)O)C[C@@H](Sc2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL2381650 Ki 138.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1ccc(Cl)cc1 CHEMBL3971347 IC50 145.0 nM
C[C@@H]1C[C@H]2[C@H](C(=O)O)[C@H]2[C@]1(N)C(=O)O CHEMBL192977 Ki 146.0 nM
Cc1ccc(N2CCn3nc(COc4ccccc4)cc3C2=O)cc1 CHEMBL3747073 EC50 150.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1ccc(Cl)c(Cl)c1 CHEMBL3909237 IC50 153.0 nM
CC(C)c1nnc(S[C@@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@@H]32)[nH]1 CHEMBL3616852 Ki 157.0 nM
COc1cccc(CC[C@](N)(C(=O)O)C2C[C@@H]2C(=O)O)c1 CHEMBL341457 IC50 160.0 nM
N[C@](CC(c1ccccc1)c1ccccc1)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL124078 IC50 170.0 nM
CC(=O)N[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL2381649 Ki 177.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1cccc(Cl)c1 CHEMBL3953570 IC50 178.0 nM
N[C@@](CCc1cccc(Cl)c1)(C(=O)O)C1C[C@@H]1C(=O)O CHEMBL333771 IC50 180.0 nM
CS(=O)(=O)c1cccc(CC[C@](N)(C(=O)O)C2C[C@@H]2C(=O)O)c1 CHEMBL2111822 IC50 180.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1cc(Cl)ccc1Cl CHEMBL3979475 IC50 185.0 nM
Clc1ccc(CN[C@H]2CCN(c3ncc(Br)cn3)C2)c(Cl)c1 CHEMBL2204436 IC50 190.0 nM
N[C@H](C(=O)O)[C@H]1[C@@H](CCC2c3ccccc3Oc3ccccc32)[C@@H]1C(=O)O CHEMBL90675 Ki 200.0 nM
Nc1cccc(CC[C@](N)(C(=O)O)C2C[C@@H]2C(=O)O)c1 CHEMBL123842 IC50 200.0 nM
N[C@H](C(=O)O)C1[C@@H](C(=O)O)[C@@H]1C(=O)O CHEMBL284193 Activity 200.0 nM
N[C@@](CCc1ccc(F)cc1)(C(=O)O)C1C[C@@H]1C(=O)O CHEMBL338282 IC50 210.0 nM
N[C@@]1(C(=O)O)C[C@@H](Sc2c[nH]nn2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL3616853 EC50 235.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@@H]1CSc1ccccc1 CHEMBL4779554 Ki 238.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@@H](O)[C@H]1OCc1ccccc1 CHEMBL3955458 IC50 239.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@@H]1CSc1ccccc1 CHEMBL4778355 Ki 251.0 nM
N[C@@](CCc1cccc(O)c1)(C(=O)O)C1C[C@@H]1C(=O)O CHEMBL124483 IC50 260.0 nM
Cc1cc(-c2cccc(C3=Nc4cc(C)c(C(F)(F)F)cc4NC(=O)C3)c2)cc(C)n1 CHEMBL1629855 IC50 270.0 nM
N[C@@]1(C(=O)O)C[C@H](Sc2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL2381651 Ki 272.0 nM
N[C@@](CC(c1ccccc1)c1ccccc1)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2311086 IC50 280.0 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)CCc2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4069251 Ki 281.0 nM
O=C1N(c2ccc(F)cc2)CCc2nc(COc3ccccc3)cn21 CHEMBL3401195 IC50 290.0 nM
O=C1c2cc(COc3ccccn3)nn2CCN1c1ccc(F)cc1 CHEMBL3747522 EC50 290.0 nM
C[C@@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]21 CHEMBL192051 Ki 302.0 nM
N[C@@]1(C(=O)O)C[C@H](NCc2ccccc2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4068679 EC50 356.0 nM
N[C@]1(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@@H]2[C@H](O)[C@H]1CSc1ccccc1F CHEMBL4755204 Ki 369.0 nM
N[C@@]1(C(=O)O)CN[C@@H](C(=O)O)C1 CHEMBL40086 Ki 410.0 nM
N[C@@](CCc1cccc(C(F)(F)F)c1)(C(=O)O)C1C[C@@H]1C(=O)O CHEMBL123847 IC50 420.0 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)CC2CCCCC2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4093017 Ki 425.0 nM
N[C@H](C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL280563 Ki 440.0 nM
NC(CCc1cccc2ccccc12)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2112583 IC50 470.0 nM
O=C1c2cc(COc3ccccc3)nn2CCCN1c1ccc(F)cc1 CHEMBL3746344 EC50 540.0 nM
NC(CCCc1ccccc1)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2112584 IC50 550.0 nM
NC(CCc1ccsc1)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2112581 IC50 570.0 nM
CC(C)SC[C@@H]1[C@@H](O)[C@H]2[C@H](C(=O)O)[C@H]2[C@]1(N)C(=O)O CHEMBL4749728 Ki 614.0 nM
O=c1n(-c2ccc(F)cc2)ccc2nc(COc3ccccc3)cn12 CHEMBL3401177 IC50 630.0 nM
CNC(=O)N1CCCC(CN2CCC(OC(c3ccccc3)c3ccccc3)CC2)C1 CHEMBL4447269 pEC50 630.96 nM
NC(CCc1ccccc1)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2112582 IC50 650.0 nM
COc1ccc(C#Cc2ccc(C(=O)N3CCC[C@@H](CO)C3)cc2)cc1 CHEMBL2204445 IC50 660.0 nM
N[C@@]1(C(=O)O)C[C@H](NC(=O)C2CCCCC2)[C@H]2[C@H](C(=O)O)[C@H]21 CHEMBL4060567 Ki 757.0 nM
NC(CCC12CC3CC(CC(C3)C1)C2)(C(=O)O)[C@H]1C[C@@H]1C(=O)O CHEMBL2112586 IC50 760.0 nM
FC(F)(F)c1c(OC[C@H]2C[C@@H]2c2ccc(Cl)cc2)ccn2c(CC3CC3)nnc12 CHEMBL3885379 EC50 890.0 nM